Amino acid dipepetide frequency for Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker s disease fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.934AlaAla: 16.934 ± 0.123
1.038AlaCys: 1.038 ± 0.017
6.027AlaAsp: 6.027 ± 0.042
5.628AlaGlu: 5.628 ± 0.062
3.255AlaPhe: 3.255 ± 0.028
8.123AlaGly: 8.123 ± 0.054
2.167AlaHis: 2.167 ± 0.024
3.92AlaIle: 3.92 ± 0.032
4.16AlaLys: 4.16 ± 0.039
8.592AlaLeu: 8.592 ± 0.055
2.162AlaMet: 2.162 ± 0.025
3.61AlaAsn: 3.61 ± 0.033
6.416AlaPro: 6.416 ± 0.067
3.93AlaGln: 3.93 ± 0.041
6.0AlaArg: 6.0 ± 0.042
9.757AlaSer: 9.757 ± 0.072
7.349AlaThr: 7.349 ± 0.048
7.133AlaVal: 7.133 ± 0.045
1.289AlaTrp: 1.289 ± 0.02
2.341AlaTyr: 2.341 ± 0.025
0.0AlaXaa: 0.0 ± 0.0
Cys
0.895CysAla: 0.895 ± 0.015
0.202CysCys: 0.202 ± 0.008
0.562CysAsp: 0.562 ± 0.011
0.457CysGlu: 0.457 ± 0.01
0.45CysPhe: 0.45 ± 0.011
0.803CysGly: 0.803 ± 0.02
0.262CysHis: 0.262 ± 0.008
0.543CysIle: 0.543 ± 0.01
0.344CysLys: 0.344 ± 0.009
1.022CysLeu: 1.022 ± 0.015
0.213CysMet: 0.213 ± 0.006
0.339CysAsn: 0.339 ± 0.009
0.537CysPro: 0.537 ± 0.014
0.347CysGln: 0.347 ± 0.008
0.653CysArg: 0.653 ± 0.014
0.708CysSer: 0.708 ± 0.013
0.614CysThr: 0.614 ± 0.013
0.728CysVal: 0.728 ± 0.013
0.154CysTrp: 0.154 ± 0.006
0.297CysTyr: 0.297 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
6.456AspAla: 6.456 ± 0.046
0.54AspCys: 0.54 ± 0.012
6.032AspAsp: 6.032 ± 0.071
4.681AspGlu: 4.681 ± 0.047
1.936AspPhe: 1.936 ± 0.021
5.041AspGly: 5.041 ± 0.04
1.237AspHis: 1.237 ± 0.016
2.524AspIle: 2.524 ± 0.023
2.401AspLys: 2.401 ± 0.029
4.752AspLeu: 4.752 ± 0.036
1.3AspMet: 1.3 ± 0.019
2.174AspAsn: 2.174 ± 0.023
3.143AspPro: 3.143 ± 0.027
1.665AspGln: 1.665 ± 0.019
3.43AspArg: 3.43 ± 0.043
3.903AspSer: 3.903 ± 0.033
3.192AspThr: 3.192 ± 0.026
4.133AspVal: 4.133 ± 0.03
0.775AspTrp: 0.775 ± 0.013
1.498AspTyr: 1.498 ± 0.021
0.0AspXaa: 0.0 ± 0.0
Glu
5.959GluAla: 5.959 ± 0.061
0.44GluCys: 0.44 ± 0.01
3.962GluAsp: 3.962 ± 0.044
4.309GluGlu: 4.309 ± 0.059
1.532GluPhe: 1.532 ± 0.018
3.245GluGly: 3.245 ± 0.033
1.22GluHis: 1.22 ± 0.018
2.179GluIle: 2.179 ± 0.025
2.729GluLys: 2.729 ± 0.035
4.412GluLeu: 4.412 ± 0.043
1.234GluMet: 1.234 ± 0.019
1.683GluAsn: 1.683 ± 0.023
2.577GluPro: 2.577 ± 0.055
2.177GluGln: 2.177 ± 0.023
3.624GluArg: 3.624 ± 0.036
3.432GluSer: 3.432 ± 0.033
3.336GluThr: 3.336 ± 0.033
2.973GluVal: 2.973 ± 0.03
0.661GluTrp: 0.661 ± 0.013
1.335GluTyr: 1.335 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
3.251PheAla: 3.251 ± 0.027
0.468PheCys: 0.468 ± 0.011
2.157PheAsp: 2.157 ± 0.022
1.675PheGlu: 1.675 ± 0.021
1.436PhePhe: 1.436 ± 0.02
2.811PheGly: 2.811 ± 0.033
0.813PheHis: 0.813 ± 0.013
1.288PheIle: 1.288 ± 0.018
1.084PheLys: 1.084 ± 0.016
3.061PheLeu: 3.061 ± 0.03
0.697PheMet: 0.697 ± 0.011
1.169PheAsn: 1.169 ± 0.016
1.726PhePro: 1.726 ± 0.022
1.204PheGln: 1.204 ± 0.018
1.885PheArg: 1.885 ± 0.02
2.626PheSer: 2.626 ± 0.025
1.822PheThr: 1.822 ± 0.021
2.516PheVal: 2.516 ± 0.027
0.544PheTrp: 0.544 ± 0.01
0.986PheTyr: 0.986 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
7.452GlyAla: 7.452 ± 0.056
0.732GlyCys: 0.732 ± 0.013
4.432GlyAsp: 4.432 ± 0.039
3.317GlyGlu: 3.317 ± 0.026
2.624GlyPhe: 2.624 ± 0.025
8.87GlyGly: 8.87 ± 0.088
1.969GlyHis: 1.969 ± 0.022
3.053GlyIle: 3.053 ± 0.033
2.958GlyLys: 2.958 ± 0.028
6.069GlyLeu: 6.069 ± 0.045
1.575GlyMet: 1.575 ± 0.02
2.779GlyAsn: 2.779 ± 0.033
3.949GlyPro: 3.949 ± 0.036
2.666GlyGln: 2.666 ± 0.026
4.817GlyArg: 4.817 ± 0.043
6.855GlySer: 6.855 ± 0.055
4.561GlyThr: 4.561 ± 0.036
4.706GlyVal: 4.706 ± 0.036
1.044GlyTrp: 1.044 ± 0.016
1.974GlyTyr: 1.974 ± 0.025
0.0GlyXaa: 0.0 ± 0.0
His
2.232HisAla: 2.232 ± 0.023
0.263HisCys: 0.263 ± 0.008
1.462HisAsp: 1.462 ± 0.021
1.154HisGlu: 1.154 ± 0.018
0.794HisPhe: 0.794 ± 0.014
1.988HisGly: 1.988 ± 0.025
1.032HisHis: 1.032 ± 0.024
1.022HisIle: 1.022 ± 0.013
0.792HisLys: 0.792 ± 0.014
2.056HisLeu: 2.056 ± 0.022
0.515HisMet: 0.515 ± 0.01
0.895HisAsn: 0.895 ± 0.015
1.593HisPro: 1.593 ± 0.02
1.102HisGln: 1.102 ± 0.022
1.607HisArg: 1.607 ± 0.019
1.741HisSer: 1.741 ± 0.021
1.277HisThr: 1.277 ± 0.016
1.501HisVal: 1.501 ± 0.018
0.299HisTrp: 0.299 ± 0.008
0.665HisTyr: 0.665 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
3.768IleAla: 3.768 ± 0.037
0.512IleCys: 0.512 ± 0.012
2.528IleAsp: 2.528 ± 0.022
2.14IleGlu: 2.14 ± 0.026
1.457IlePhe: 1.457 ± 0.021
2.822IleGly: 2.822 ± 0.031
0.939IleHis: 0.939 ± 0.015
1.626IleIle: 1.626 ± 0.023
1.532IleLys: 1.532 ± 0.021
3.547IleLeu: 3.547 ± 0.033
0.816IleMet: 0.816 ± 0.013
1.436IleAsn: 1.436 ± 0.02
2.382IlePro: 2.382 ± 0.026
1.471IleGln: 1.471 ± 0.02
2.35IleArg: 2.35 ± 0.024
2.712IleSer: 2.712 ± 0.025
2.212IleThr: 2.212 ± 0.026
3.077IleVal: 3.077 ± 0.03
0.533IleTrp: 0.533 ± 0.01
1.062IleTyr: 1.062 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.291LysAla: 4.291 ± 0.038
0.33LysCys: 0.33 ± 0.01
2.414LysAsp: 2.414 ± 0.028
2.519LysGlu: 2.519 ± 0.037
1.048LysPhe: 1.048 ± 0.016
2.408LysGly: 2.408 ± 0.026
0.902LysHis: 0.902 ± 0.013
1.613LysIle: 1.613 ± 0.023
2.841LysLys: 2.841 ± 0.054
3.135LysLeu: 3.135 ± 0.033
0.858LysMet: 0.858 ± 0.014
1.435LysAsn: 1.435 ± 0.019
2.306LysPro: 2.306 ± 0.029
1.591LysGln: 1.591 ± 0.021
2.92LysArg: 2.92 ± 0.033
2.71LysSer: 2.71 ± 0.03
2.718LysThr: 2.718 ± 0.028
2.238LysVal: 2.238 ± 0.026
0.465LysTrp: 0.465 ± 0.011
1.015LysTyr: 1.015 ± 0.016
0.0LysXaa: 0.0 ± 0.0
Leu
9.16LeuAla: 9.16 ± 0.066
1.014LeuCys: 1.014 ± 0.017
5.036LeuAsp: 5.036 ± 0.035
4.44LeuGlu: 4.44 ± 0.035
3.09LeuPhe: 3.09 ± 0.033
5.849LeuGly: 5.849 ± 0.046
2.13LeuHis: 2.13 ± 0.025
2.867LeuIle: 2.867 ± 0.032
3.071LeuLys: 3.071 ± 0.033
8.008LeuLeu: 8.008 ± 0.069
1.571LeuMet: 1.571 ± 0.019
2.503LeuAsn: 2.503 ± 0.025
5.672LeuPro: 5.672 ± 0.039
3.717LeuGln: 3.717 ± 0.037
5.798LeuArg: 5.798 ± 0.045
6.586LeuSer: 6.586 ± 0.045
4.487LeuThr: 4.487 ± 0.034
5.72LeuVal: 5.72 ± 0.045
1.093LeuTrp: 1.093 ± 0.016
2.164LeuTyr: 2.164 ± 0.024
0.0LeuXaa: 0.0 ± 0.0
Met
2.637MetAla: 2.637 ± 0.023
0.207MetCys: 0.207 ± 0.007
1.257MetAsp: 1.257 ± 0.019
1.002MetGlu: 1.002 ± 0.013
0.643MetPhe: 0.643 ± 0.012
1.439MetGly: 1.439 ± 0.02
0.511MetHis: 0.511 ± 0.01
0.734MetIle: 0.734 ± 0.015
0.699MetLys: 0.699 ± 0.012
1.748MetLeu: 1.748 ± 0.021
0.52MetMet: 0.52 ± 0.011
0.643MetAsn: 0.643 ± 0.012
1.349MetPro: 1.349 ± 0.019
0.85MetGln: 0.85 ± 0.015
1.263MetArg: 1.263 ± 0.017
1.76MetSer: 1.76 ± 0.017
1.255MetThr: 1.255 ± 0.015
1.257MetVal: 1.257 ± 0.015
0.224MetTrp: 0.224 ± 0.007
0.501MetTyr: 0.501 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.468AsnAla: 3.468 ± 0.032
0.36AsnCys: 0.36 ± 0.01
2.103AsnAsp: 2.103 ± 0.022
1.701AsnGlu: 1.701 ± 0.019
1.125AsnPhe: 1.125 ± 0.016
3.529AsnGly: 3.529 ± 0.035
0.775AsnHis: 0.775 ± 0.013
1.557AsnIle: 1.557 ± 0.016
1.372AsnLys: 1.372 ± 0.018
2.691AsnLeu: 2.691 ± 0.028
0.801AsnMet: 0.801 ± 0.015
1.889AsnAsn: 1.889 ± 0.039
1.986AsnPro: 1.986 ± 0.025
1.126AsnGln: 1.126 ± 0.019
1.858AsnArg: 1.858 ± 0.019
2.626AsnSer: 2.626 ± 0.03
2.189AsnThr: 2.189 ± 0.026
2.227AsnVal: 2.227 ± 0.025
0.449AsnTrp: 0.449 ± 0.01
0.924AsnTyr: 0.924 ± 0.014
0.0AsnXaa: 0.0 ± 0.0
Pro
7.27ProAla: 7.27 ± 0.062
0.439ProCys: 0.439 ± 0.011
3.233ProAsp: 3.233 ± 0.031
3.099ProGlu: 3.099 ± 0.036
1.903ProPhe: 1.903 ± 0.021
4.429ProGly: 4.429 ± 0.037
1.384ProHis: 1.384 ± 0.019
2.135ProIle: 2.135 ± 0.02
2.184ProLys: 2.184 ± 0.026
4.918ProLeu: 4.918 ± 0.035
1.112ProMet: 1.112 ± 0.02
2.004ProAsn: 2.004 ± 0.023
6.535ProPro: 6.535 ± 0.102
2.585ProGln: 2.585 ± 0.038
3.505ProArg: 3.505 ± 0.036
6.268ProSer: 6.268 ± 0.061
4.456ProThr: 4.456 ± 0.044
4.046ProVal: 4.046 ± 0.041
0.67ProTrp: 0.67 ± 0.013
1.443ProTyr: 1.443 ± 0.021
0.0ProXaa: 0.0 ± 0.0
Gln
3.903GlnAla: 3.903 ± 0.04
0.357GlnCys: 0.357 ± 0.009
1.855GlnAsp: 1.855 ± 0.022
1.898GlnGlu: 1.898 ± 0.023
1.207GlnPhe: 1.207 ± 0.019
2.279GlnGly: 2.279 ± 0.026
1.312GlnHis: 1.312 ± 0.026
1.505GlnIle: 1.505 ± 0.021
1.592GlnLys: 1.592 ± 0.021
3.443GlnLeu: 3.443 ± 0.031
0.884GlnMet: 0.884 ± 0.014
1.354GlnAsn: 1.354 ± 0.021
2.874GlnPro: 2.874 ± 0.04
4.204GlnGln: 4.204 ± 0.105
2.842GlnArg: 2.842 ± 0.027
2.84GlnSer: 2.84 ± 0.028
2.366GlnThr: 2.366 ± 0.025
2.023GlnVal: 2.023 ± 0.023
0.523GlnTrp: 0.523 ± 0.011
1.064GlnTyr: 1.064 ± 0.018
0.0GlnXaa: 0.0 ± 0.0
Arg
5.655ArgAla: 5.655 ± 0.037
0.645ArgCys: 0.645 ± 0.013
3.713ArgAsp: 3.713 ± 0.044
3.434ArgGlu: 3.434 ± 0.036
2.047ArgPhe: 2.047 ± 0.02
4.137ArgGly: 4.137 ± 0.044
1.71ArgHis: 1.71 ± 0.021
2.562ArgIle: 2.562 ± 0.023
2.911ArgLys: 2.911 ± 0.031
5.568ArgLeu: 5.568 ± 0.04
1.327ArgMet: 1.327 ± 0.016
2.135ArgAsn: 2.135 ± 0.023
3.97ArgPro: 3.97 ± 0.036
2.852ArgGln: 2.852 ± 0.025
5.945ArgArg: 5.945 ± 0.046
4.774ArgSer: 4.774 ± 0.046
3.476ArgThr: 3.476 ± 0.028
3.567ArgVal: 3.567 ± 0.03
0.887ArgTrp: 0.887 ± 0.014
1.585ArgTyr: 1.585 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
8.491SerAla: 8.491 ± 0.065
0.672SerCys: 0.672 ± 0.013
4.215SerAsp: 4.215 ± 0.037
3.274SerGlu: 3.274 ± 0.031
2.697SerPhe: 2.697 ± 0.025
6.66SerGly: 6.66 ± 0.051
1.853SerHis: 1.853 ± 0.021
3.214SerIle: 3.214 ± 0.03
2.987SerLys: 2.987 ± 0.026
6.58SerLeu: 6.58 ± 0.044
1.63SerMet: 1.63 ± 0.023
2.942SerAsn: 2.942 ± 0.028
5.727SerPro: 5.727 ± 0.059
2.907SerGln: 2.907 ± 0.029
4.883SerArg: 4.883 ± 0.045
10.355SerSer: 10.355 ± 0.119
6.058SerThr: 6.058 ± 0.049
4.877SerVal: 4.877 ± 0.036
0.91SerTrp: 0.91 ± 0.014
1.852SerTyr: 1.852 ± 0.023
0.0SerXaa: 0.0 ± 0.0
Thr
7.415ThrAla: 7.415 ± 0.049
0.617ThrCys: 0.617 ± 0.012
3.145ThrAsp: 3.145 ± 0.033
2.806ThrGlu: 2.806 ± 0.03
2.037ThrPhe: 2.037 ± 0.022
4.672ThrGly: 4.672 ± 0.034
1.241ThrHis: 1.241 ± 0.015
2.563ThrIle: 2.563 ± 0.022
2.417ThrLys: 2.417 ± 0.03
4.946ThrLeu: 4.946 ± 0.033
1.182ThrMet: 1.182 ± 0.015
2.205ThrAsn: 2.205 ± 0.024
4.84ThrPro: 4.84 ± 0.05
2.003ThrGln: 2.003 ± 0.022
3.193ThrArg: 3.193 ± 0.031
5.768ThrSer: 5.768 ± 0.049
5.389ThrThr: 5.389 ± 0.055
4.114ThrVal: 4.114 ± 0.034
0.746ThrTrp: 0.746 ± 0.012
1.469ThrTyr: 1.469 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
7.142ValAla: 7.142 ± 0.053
0.782ValCys: 0.782 ± 0.012
4.21ValAsp: 4.21 ± 0.033
3.489ValGlu: 3.489 ± 0.035
2.423ValPhe: 2.423 ± 0.029
4.371ValGly: 4.371 ± 0.033
1.537ValHis: 1.537 ± 0.019
2.376ValIle: 2.376 ± 0.026
2.255ValLys: 2.255 ± 0.022
5.904ValLeu: 5.904 ± 0.049
1.209ValMet: 1.209 ± 0.018
2.052ValAsn: 2.052 ± 0.024
4.163ValPro: 4.163 ± 0.035
2.432ValGln: 2.432 ± 0.022
3.882ValArg: 3.882 ± 0.032
4.74ValSer: 4.74 ± 0.04
3.675ValThr: 3.675 ± 0.031
5.049ValVal: 5.049 ± 0.046
0.868ValTrp: 0.868 ± 0.014
1.764ValTyr: 1.764 ± 0.02
0.0ValXaa: 0.0 ± 0.0
Trp
1.155TrpAla: 1.155 ± 0.018
0.162TrpCys: 0.162 ± 0.005
0.796TrpAsp: 0.796 ± 0.013
0.634TrpGlu: 0.634 ± 0.011
0.459TrpPhe: 0.459 ± 0.011
0.826TrpGly: 0.826 ± 0.017
0.34TrpHis: 0.34 ± 0.008
0.561TrpIle: 0.561 ± 0.012
0.558TrpLys: 0.558 ± 0.01
1.21TrpLeu: 1.21 ± 0.017
0.324TrpMet: 0.324 ± 0.008
0.487TrpAsn: 0.487 ± 0.011
0.607TrpPro: 0.607 ± 0.011
0.552TrpGln: 0.552 ± 0.012
0.903TrpArg: 0.903 ± 0.014
0.9TrpSer: 0.9 ± 0.015
0.881TrpThr: 0.881 ± 0.016
0.789TrpVal: 0.789 ± 0.012
0.251TrpTrp: 0.251 ± 0.008
0.368TrpTyr: 0.368 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.295TyrAla: 2.295 ± 0.022
0.346TyrCys: 0.346 ± 0.009
1.674TyrAsp: 1.674 ± 0.022
1.364TyrGlu: 1.364 ± 0.018
1.056TyrPhe: 1.056 ± 0.017
2.099TyrGly: 2.099 ± 0.023
0.659TyrHis: 0.659 ± 0.012
1.081TyrIle: 1.081 ± 0.017
0.869TyrLys: 0.869 ± 0.015
2.317TyrLeu: 2.317 ± 0.027
0.57TyrMet: 0.57 ± 0.011
1.025TyrAsn: 1.025 ± 0.016
1.264TyrPro: 1.264 ± 0.017
0.943TyrGln: 0.943 ± 0.017
1.54TyrArg: 1.54 ± 0.021
1.721TyrSer: 1.721 ± 0.023
1.453TyrThr: 1.453 ± 0.021
1.652TyrVal: 1.652 ± 0.018
0.376TyrTrp: 0.376 ± 0.009
0.902TyrTyr: 0.902 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8673 proteins (4783716 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski