Amino acid dipepetide frequency for Alternaria alternata virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.768AlaAla: 11.768 ± 2.145
1.59AlaCys: 1.59 ± 0.356
8.906AlaAsp: 8.906 ± 0.505
8.588AlaGlu: 8.588 ± 1.833
5.089AlaPhe: 5.089 ± 0.117
7.316AlaGly: 7.316 ± 1.239
2.545AlaHis: 2.545 ± 0.431
3.817AlaIle: 3.817 ± 0.979
3.181AlaLys: 3.181 ± 1.361
7.952AlaLeu: 7.952 ± 2.146
1.59AlaMet: 1.59 ± 0.678
3.181AlaAsn: 3.181 ± 0.758
3.817AlaPro: 3.817 ± 0.741
1.59AlaGln: 1.59 ± 0.492
6.679AlaArg: 6.679 ± 1.476
6.997AlaSer: 6.997 ± 0.606
5.089AlaThr: 5.089 ± 0.731
6.679AlaVal: 6.679 ± 1.112
4.453AlaTrp: 4.453 ± 1.375
3.817AlaTyr: 3.817 ± 0.779
0.0AlaXaa: 0.0 ± 0.0
Cys
0.954CysAla: 0.954 ± 0.394
0.318CysCys: 0.318 ± 0.367
1.272CysAsp: 1.272 ± 0.655
0.318CysGlu: 0.318 ± 0.281
0.0CysPhe: 0.0 ± 0.0
2.545CysGly: 2.545 ± 1.102
0.318CysHis: 0.318 ± 0.253
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.954CysLeu: 0.954 ± 0.451
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.636CysPro: 0.636 ± 0.268
0.318CysGln: 0.318 ± 0.253
0.954CysArg: 0.954 ± 0.176
1.59CysSer: 1.59 ± 0.6
0.636CysThr: 0.636 ± 0.367
0.954CysVal: 0.954 ± 0.394
0.0CysTrp: 0.0 ± 0.0
1.272CysTyr: 1.272 ± 0.49
0.0CysXaa: 0.0 ± 0.0
Asp
6.997AspAla: 6.997 ± 1.18
0.318AspCys: 0.318 ± 0.253
5.089AspAsp: 5.089 ± 1.547
3.817AspGlu: 3.817 ± 1.035
3.181AspPhe: 3.181 ± 0.965
6.043AspGly: 6.043 ± 1.246
1.272AspHis: 1.272 ± 0.383
1.59AspIle: 1.59 ± 0.632
3.181AspLys: 3.181 ± 1.116
7.316AspLeu: 7.316 ± 1.188
1.272AspMet: 1.272 ± 0.384
0.0AspAsn: 0.0 ± 0.0
4.135AspPro: 4.135 ± 2.228
1.59AspGln: 1.59 ± 0.592
6.043AspArg: 6.043 ± 1.682
2.226AspSer: 2.226 ± 0.515
2.545AspThr: 2.545 ± 0.733
8.588AspVal: 8.588 ± 1.892
1.59AspTrp: 1.59 ± 0.632
2.226AspTyr: 2.226 ± 0.621
0.0AspXaa: 0.0 ± 0.0
Glu
3.817GluAla: 3.817 ± 0.677
0.636GluCys: 0.636 ± 0.343
2.863GluAsp: 2.863 ± 0.894
2.545GluGlu: 2.545 ± 0.431
0.954GluPhe: 0.954 ± 0.394
6.043GluGly: 6.043 ± 1.266
0.954GluHis: 0.954 ± 0.176
1.908GluIle: 1.908 ± 0.756
1.908GluLys: 1.908 ± 0.688
4.135GluLeu: 4.135 ± 1.308
2.226GluMet: 2.226 ± 0.251
0.0GluAsn: 0.0 ± 0.0
2.226GluPro: 2.226 ± 0.65
0.954GluGln: 0.954 ± 0.345
6.043GluArg: 6.043 ± 0.348
1.908GluSer: 1.908 ± 0.485
1.908GluThr: 1.908 ± 0.263
7.634GluVal: 7.634 ± 1.49
0.318GluTrp: 0.318 ± 0.253
1.272GluTyr: 1.272 ± 1.013
0.0GluXaa: 0.0 ± 0.0
Phe
2.863PheAla: 2.863 ± 1.566
1.272PheCys: 1.272 ± 0.659
1.59PheAsp: 1.59 ± 0.706
1.59PheGlu: 1.59 ± 0.196
1.59PhePhe: 1.59 ± 0.428
4.771PheGly: 4.771 ± 0.49
1.272PheHis: 1.272 ± 1.122
0.318PheIle: 0.318 ± 0.281
1.272PheLys: 1.272 ± 1.013
2.545PheLeu: 2.545 ± 0.761
0.318PheMet: 0.318 ± 0.281
0.636PheAsn: 0.636 ± 0.268
2.863PhePro: 2.863 ± 0.993
0.954PheGln: 0.954 ± 0.326
2.545PheArg: 2.545 ± 0.623
2.545PheSer: 2.545 ± 0.867
1.908PheThr: 1.908 ± 0.691
3.817PheVal: 3.817 ± 0.794
1.272PheTrp: 1.272 ± 0.459
0.954PheTyr: 0.954 ± 0.466
0.0PheXaa: 0.0 ± 0.0
Gly
7.316GlyAla: 7.316 ± 1.414
1.59GlyCys: 1.59 ± 0.196
6.679GlyAsp: 6.679 ± 0.834
3.181GlyGlu: 3.181 ± 0.984
5.089GlyPhe: 5.089 ± 1.022
15.267GlyGly: 15.267 ± 3.03
1.272GlyHis: 1.272 ± 0.681
0.954GlyIle: 0.954 ± 0.76
3.499GlyLys: 3.499 ± 1.535
9.542GlyLeu: 9.542 ± 2.52
3.181GlyMet: 3.181 ± 1.071
2.863GlyAsn: 2.863 ± 1.396
3.817GlyPro: 3.817 ± 0.73
2.226GlyGln: 2.226 ± 0.526
7.316GlyArg: 7.316 ± 0.617
9.86GlySer: 9.86 ± 1.429
4.135GlyThr: 4.135 ± 1.125
11.45GlyVal: 11.45 ± 2.111
4.453GlyTrp: 4.453 ± 0.998
2.226GlyTyr: 2.226 ± 0.789
0.0GlyXaa: 0.0 ± 0.0
His
1.908HisAla: 1.908 ± 0.263
0.0HisCys: 0.0 ± 0.0
0.954HisAsp: 0.954 ± 0.176
0.954HisGlu: 0.954 ± 0.57
0.954HisPhe: 0.954 ± 0.345
1.272HisGly: 1.272 ± 0.383
1.272HisHis: 1.272 ± 0.38
0.318HisIle: 0.318 ± 0.262
0.954HisLys: 0.954 ± 0.76
2.226HisLeu: 2.226 ± 0.526
0.954HisMet: 0.954 ± 0.406
0.0HisAsn: 0.0 ± 0.0
1.272HisPro: 1.272 ± 0.383
0.318HisGln: 0.318 ± 0.253
1.59HisArg: 1.59 ± 0.492
0.636HisSer: 0.636 ± 0.367
1.272HisThr: 1.272 ± 0.83
3.499HisVal: 3.499 ± 1.344
0.954HisTrp: 0.954 ± 0.326
0.636HisTyr: 0.636 ± 0.268
0.0HisXaa: 0.0 ± 0.0
Ile
1.59IleAla: 1.59 ± 0.635
0.0IleCys: 0.0 ± 0.0
2.545IleAsp: 2.545 ± 0.64
0.636IleGlu: 0.636 ± 0.507
0.954IlePhe: 0.954 ± 0.394
1.908IleGly: 1.908 ± 0.888
0.318IleHis: 0.318 ± 0.367
0.318IleIle: 0.318 ± 0.253
1.908IleLys: 1.908 ± 0.712
1.59IleLeu: 1.59 ± 0.313
0.954IleMet: 0.954 ± 0.488
0.0IleAsn: 0.0 ± 0.0
2.226IlePro: 2.226 ± 0.615
0.318IleGln: 0.318 ± 0.253
1.272IleArg: 1.272 ± 0.681
1.272IleSer: 1.272 ± 0.681
0.954IleThr: 0.954 ± 0.394
0.954IleVal: 0.954 ± 0.786
0.0IleTrp: 0.0 ± 0.0
1.59IleTyr: 1.59 ± 0.923
0.0IleXaa: 0.0 ± 0.0
Lys
4.135LysAla: 4.135 ± 1.717
0.318LysCys: 0.318 ± 0.253
1.59LysAsp: 1.59 ± 0.864
2.226LysGlu: 2.226 ± 1.077
1.908LysPhe: 1.908 ± 0.421
3.181LysGly: 3.181 ± 1.334
0.318LysHis: 0.318 ± 0.281
0.318LysIle: 0.318 ± 0.281
1.908LysLys: 1.908 ± 1.52
3.499LysLeu: 3.499 ± 0.698
0.318LysMet: 0.318 ± 0.253
0.318LysAsn: 0.318 ± 0.253
0.318LysPro: 0.318 ± 0.281
0.636LysGln: 0.636 ± 0.367
3.817LysArg: 3.817 ± 1.574
0.318LysSer: 0.318 ± 0.281
1.59LysThr: 1.59 ± 0.635
2.226LysVal: 2.226 ± 0.693
0.636LysTrp: 0.636 ± 0.268
1.272LysTyr: 1.272 ± 0.459
0.0LysXaa: 0.0 ± 0.0
Leu
9.542LeuAla: 9.542 ± 3.714
0.954LeuCys: 0.954 ± 0.76
6.361LeuAsp: 6.361 ± 1.185
5.407LeuGlu: 5.407 ± 0.818
1.59LeuPhe: 1.59 ± 0.483
10.178LeuGly: 10.178 ± 1.888
1.908LeuHis: 1.908 ± 0.51
2.226LeuIle: 2.226 ± 1.127
1.908LeuLys: 1.908 ± 1.257
14.631LeuLeu: 14.631 ± 2.092
1.908LeuMet: 1.908 ± 0.351
2.545LeuAsn: 2.545 ± 0.455
4.771LeuPro: 4.771 ± 1.257
2.545LeuGln: 2.545 ± 0.455
8.27LeuArg: 8.27 ± 0.282
8.906LeuSer: 8.906 ± 1.387
3.181LeuThr: 3.181 ± 0.322
4.135LeuVal: 4.135 ± 1.277
2.226LeuTrp: 2.226 ± 1.015
1.908LeuTyr: 1.908 ± 0.805
0.0LeuXaa: 0.0 ± 0.0
Met
3.817MetAla: 3.817 ± 1.139
0.318MetCys: 0.318 ± 0.281
0.954MetAsp: 0.954 ± 0.326
0.954MetGlu: 0.954 ± 0.394
0.636MetPhe: 0.636 ± 0.367
0.954MetGly: 0.954 ± 0.842
0.0MetHis: 0.0 ± 0.0
0.318MetIle: 0.318 ± 0.281
0.636MetLys: 0.636 ± 0.367
2.863MetLeu: 2.863 ± 1.154
0.318MetMet: 0.318 ± 0.253
0.636MetAsn: 0.636 ± 0.367
1.59MetPro: 1.59 ± 0.809
0.954MetGln: 0.954 ± 0.445
1.908MetArg: 1.908 ± 0.735
1.272MetSer: 1.272 ± 0.459
0.318MetThr: 0.318 ± 0.253
3.181MetVal: 3.181 ± 0.313
0.0MetTrp: 0.0 ± 0.0
1.272MetTyr: 1.272 ± 0.38
0.0MetXaa: 0.0 ± 0.0
Asn
1.908AsnAla: 1.908 ± 0.841
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.59AsnGlu: 1.59 ± 0.497
1.272AsnPhe: 1.272 ± 0.432
1.272AsnGly: 1.272 ± 0.383
0.318AsnHis: 0.318 ± 0.262
0.636AsnIle: 0.636 ± 0.507
0.636AsnLys: 0.636 ± 0.507
2.226AsnLeu: 2.226 ± 0.462
0.954AsnMet: 0.954 ± 0.466
0.318AsnAsn: 0.318 ± 0.253
0.318AsnPro: 0.318 ± 0.281
0.318AsnGln: 0.318 ± 0.253
1.59AsnArg: 1.59 ± 0.313
0.636AsnSer: 0.636 ± 0.268
0.318AsnThr: 0.318 ± 0.253
1.272AsnVal: 1.272 ± 0.707
0.0AsnTrp: 0.0 ± 0.0
0.954AsnTyr: 0.954 ± 0.466
0.0AsnXaa: 0.0 ± 0.0
Pro
7.316ProAla: 7.316 ± 1.831
0.954ProCys: 0.954 ± 0.46
4.135ProAsp: 4.135 ± 0.351
2.545ProGlu: 2.545 ± 0.867
1.272ProPhe: 1.272 ± 0.758
6.679ProGly: 6.679 ± 1.04
0.954ProHis: 0.954 ± 0.601
0.954ProIle: 0.954 ± 0.445
1.59ProLys: 1.59 ± 0.698
2.226ProLeu: 2.226 ± 0.662
0.636ProMet: 0.636 ± 0.268
0.954ProAsn: 0.954 ± 0.513
6.361ProPro: 6.361 ± 2.536
0.954ProGln: 0.954 ± 0.46
2.545ProArg: 2.545 ± 0.652
2.226ProSer: 2.226 ± 0.883
1.59ProThr: 1.59 ± 0.898
5.089ProVal: 5.089 ± 0.986
1.908ProTrp: 1.908 ± 0.38
1.272ProTyr: 1.272 ± 0.78
0.0ProXaa: 0.0 ± 0.0
Gln
3.817GlnAla: 3.817 ± 0.936
0.318GlnCys: 0.318 ± 0.253
1.272GlnAsp: 1.272 ± 0.621
0.636GlnGlu: 0.636 ± 0.343
0.954GlnPhe: 0.954 ± 0.394
4.453GlnGly: 4.453 ± 1.368
0.636GlnHis: 0.636 ± 0.268
0.318GlnIle: 0.318 ± 0.262
0.318GlnLys: 0.318 ± 0.367
2.545GlnLeu: 2.545 ± 0.455
0.636GlnMet: 0.636 ± 0.424
0.0GlnAsn: 0.0 ± 0.0
0.318GlnPro: 0.318 ± 0.281
0.954GlnGln: 0.954 ± 0.394
2.226GlnArg: 2.226 ± 0.534
1.59GlnSer: 1.59 ± 0.356
0.636GlnThr: 0.636 ± 0.367
2.863GlnVal: 2.863 ± 1.122
0.954GlnTrp: 0.954 ± 0.326
0.318GlnTyr: 0.318 ± 0.281
0.0GlnXaa: 0.0 ± 0.0
Arg
10.178ArgAla: 10.178 ± 2.58
0.318ArgCys: 0.318 ± 0.367
6.679ArgAsp: 6.679 ± 2.313
5.407ArgGlu: 5.407 ± 0.818
1.908ArgPhe: 1.908 ± 0.564
7.316ArgGly: 7.316 ± 0.922
2.226ArgHis: 2.226 ± 0.376
2.545ArgIle: 2.545 ± 0.455
2.545ArgLys: 2.545 ± 0.493
6.361ArgLeu: 6.361 ± 1.256
2.545ArgMet: 2.545 ± 0.453
1.59ArgAsn: 1.59 ± 0.492
4.135ArgPro: 4.135 ± 0.646
2.545ArgGln: 2.545 ± 1.019
5.725ArgArg: 5.725 ± 1.455
4.453ArgSer: 4.453 ± 1.013
3.499ArgThr: 3.499 ± 0.396
6.679ArgVal: 6.679 ± 2.525
1.272ArgTrp: 1.272 ± 0.536
3.817ArgTyr: 3.817 ± 0.387
0.0ArgXaa: 0.0 ± 0.0
Ser
9.224SerAla: 9.224 ± 1.44
0.954SerCys: 0.954 ± 0.763
5.725SerAsp: 5.725 ± 0.704
1.908SerGlu: 1.908 ± 0.616
3.181SerPhe: 3.181 ± 1.428
6.043SerGly: 6.043 ± 0.759
1.908SerHis: 1.908 ± 0.51
1.59SerIle: 1.59 ± 0.196
2.863SerLys: 2.863 ± 0.512
4.771SerLeu: 4.771 ± 0.587
0.636SerMet: 0.636 ± 0.507
0.954SerAsn: 0.954 ± 0.451
3.817SerPro: 3.817 ± 1.151
1.59SerGln: 1.59 ± 0.313
5.407SerArg: 5.407 ± 0.951
4.771SerSer: 4.771 ± 1.193
2.226SerThr: 2.226 ± 0.807
7.316SerVal: 7.316 ± 2.629
1.59SerTrp: 1.59 ± 0.483
0.636SerTyr: 0.636 ± 0.268
0.0SerXaa: 0.0 ± 0.0
Thr
3.817ThrAla: 3.817 ± 0.778
0.954ThrCys: 0.954 ± 0.326
2.226ThrAsp: 2.226 ± 0.688
1.908ThrGlu: 1.908 ± 0.351
1.59ThrPhe: 1.59 ± 0.492
3.499ThrGly: 3.499 ± 0.62
0.318ThrHis: 0.318 ± 0.262
0.636ThrIle: 0.636 ± 0.507
0.954ThrLys: 0.954 ± 0.176
4.453ThrLeu: 4.453 ± 0.993
0.636ThrMet: 0.636 ± 0.229
0.954ThrAsn: 0.954 ± 0.176
1.272ThrPro: 1.272 ± 0.384
1.272ThrGln: 1.272 ± 1.122
3.181ThrArg: 3.181 ± 1.132
4.135ThrSer: 4.135 ± 1.125
0.636ThrThr: 0.636 ± 0.343
4.135ThrVal: 4.135 ± 0.829
1.272ThrTrp: 1.272 ± 0.621
0.636ThrTyr: 0.636 ± 0.367
0.0ThrXaa: 0.0 ± 0.0
Val
9.542ValAla: 9.542 ± 0.999
1.272ValCys: 1.272 ± 0.38
5.089ValAsp: 5.089 ± 0.381
4.453ValGlu: 4.453 ± 0.865
3.181ValPhe: 3.181 ± 0.544
10.178ValGly: 10.178 ± 2.629
2.545ValHis: 2.545 ± 0.433
1.59ValIle: 1.59 ± 0.313
0.636ValLys: 0.636 ± 0.424
8.906ValLeu: 8.906 ± 1.104
2.545ValMet: 2.545 ± 0.455
1.272ValAsn: 1.272 ± 0.536
6.043ValPro: 6.043 ± 1.361
4.135ValGln: 4.135 ± 0.528
8.27ValArg: 8.27 ± 1.098
8.27ValSer: 8.27 ± 2.501
2.226ValThr: 2.226 ± 0.534
9.86ValVal: 9.86 ± 2.614
0.954ValTrp: 0.954 ± 0.466
1.59ValTyr: 1.59 ± 0.313
0.0ValXaa: 0.0 ± 0.0
Trp
1.272TrpAla: 1.272 ± 0.825
0.318TrpCys: 0.318 ± 0.253
2.545TrpAsp: 2.545 ± 0.765
0.636TrpGlu: 0.636 ± 0.229
0.0TrpPhe: 0.0 ± 0.0
4.453TrpGly: 4.453 ± 1.242
0.954TrpHis: 0.954 ± 0.445
0.318TrpIle: 0.318 ± 0.253
0.318TrpLys: 0.318 ± 0.262
3.499TrpLeu: 3.499 ± 0.654
0.954TrpMet: 0.954 ± 0.76
0.318TrpAsn: 0.318 ± 0.262
1.59TrpPro: 1.59 ± 0.706
0.954TrpGln: 0.954 ± 0.513
1.908TrpArg: 1.908 ± 0.735
1.908TrpSer: 1.908 ± 0.351
0.636TrpThr: 0.636 ± 0.268
0.636TrpVal: 0.636 ± 0.343
0.636TrpTrp: 0.636 ± 0.268
0.636TrpTyr: 0.636 ± 0.367
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.181TyrAla: 3.181 ± 0.669
0.636TyrCys: 0.636 ± 0.343
2.545TyrAsp: 2.545 ± 0.893
0.954TyrGlu: 0.954 ± 0.176
1.59TyrPhe: 1.59 ± 0.356
2.545TyrGly: 2.545 ± 0.433
0.636TyrHis: 0.636 ± 0.268
0.636TyrIle: 0.636 ± 0.424
0.636TyrLys: 0.636 ± 0.507
2.863TyrLeu: 2.863 ± 0.578
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.636TyrPro: 0.636 ± 0.268
0.636TyrGln: 0.636 ± 0.524
4.453TyrArg: 4.453 ± 0.421
1.59TyrSer: 1.59 ± 0.196
3.181TyrThr: 3.181 ± 0.669
1.59TyrVal: 1.59 ± 0.356
0.0TyrTrp: 0.0 ± 0.0
0.954TyrTyr: 0.954 ± 0.76
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3145 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski