Amino acid dipepetide frequency for Salmonella bongori

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.707AlaAla: 9.707 ± 0.12	1.241AlaCys: 1.241 ± 0.032	4.92AlaAsp: 4.92 ± 0.067	5.312AlaGlu: 5.312 ± 0.078	3.618AlaPhe: 3.618 ± 0.049	7.769AlaGly: 7.769 ± 0.087	1.99AlaHis: 1.99 ± 0.043	5.833AlaIle: 5.833 ± 0.07	3.826AlaLys: 3.826 ± 0.054	11.326AlaLeu: 11.326 ± 0.103	3.119AlaMet: 3.119 ± 0.056	3.147AlaAsn: 3.147 ± 0.059	3.733AlaPro: 3.733 ± 0.059	4.385AlaGln: 4.385 ± 0.07	5.696AlaArg: 5.696 ± 0.078	5.484AlaSer: 5.484 ± 0.076	4.969AlaThr: 4.969 ± 0.07	6.528AlaVal: 6.528 ± 0.083	1.673AlaTrp: 1.673 ± 0.038	2.01AlaTyr: 2.01 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	1.157CysAla: 1.157 ± 0.031	0.263CysCys: 0.263 ± 0.016	0.626CysAsp: 0.626 ± 0.021	0.629CysGlu: 0.629 ± 0.027	0.497CysPhe: 0.497 ± 0.021	1.201CysGly: 1.201 ± 0.032	0.388CysHis: 0.388 ± 0.017	0.651CysIle: 0.651 ± 0.022	0.382CysLys: 0.382 ± 0.018	1.139CysLeu: 1.139 ± 0.034	0.348CysMet: 0.348 ± 0.018	0.343CysAsn: 0.343 ± 0.018	0.621CysPro: 0.621 ± 0.026	0.534CysGln: 0.534 ± 0.02	0.96CysArg: 0.96 ± 0.03	0.747CysSer: 0.747 ± 0.023	0.552CysThr: 0.552 ± 0.02	0.841CysVal: 0.841 ± 0.031	0.271CysTrp: 0.271 ± 0.014	0.389CysTyr: 0.389 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	5.194AspAla: 5.194 ± 0.072	0.537AspCys: 0.537 ± 0.021	2.916AspAsp: 2.916 ± 0.054	3.35AspGlu: 3.35 ± 0.061	2.015AspPhe: 2.015 ± 0.043	3.809AspGly: 3.809 ± 0.067	1.006AspHis: 1.006 ± 0.027	3.525AspIle: 3.525 ± 0.058	2.561AspLys: 2.561 ± 0.047	4.432AspLeu: 4.432 ± 0.068	1.381AspMet: 1.381 ± 0.027	2.301AspAsn: 2.301 ± 0.047	2.207AspPro: 2.207 ± 0.046	1.428AspGln: 1.428 ± 0.036	2.639AspArg: 2.639 ± 0.047	2.862AspSer: 2.862 ± 0.05	2.676AspThr: 2.676 ± 0.059	3.719AspVal: 3.719 ± 0.065	0.797AspTrp: 0.797 ± 0.029	1.817AspTyr: 1.817 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	5.025GluAla: 5.025 ± 0.084	0.506GluCys: 0.506 ± 0.024	2.285GluAsp: 2.285 ± 0.045	3.203GluGlu: 3.203 ± 0.061	1.745GluPhe: 1.745 ± 0.039	3.533GluGly: 3.533 ± 0.06	1.336GluHis: 1.336 ± 0.037	3.219GluIle: 3.219 ± 0.061	3.27GluLys: 3.27 ± 0.054	5.499GluLeu: 5.499 ± 0.079	1.709GluMet: 1.709 ± 0.042	2.418GluAsn: 2.418 ± 0.042	1.987GluPro: 1.987 ± 0.039	3.126GluGln: 3.126 ± 0.06	3.593GluArg: 3.593 ± 0.062	2.866GluSer: 2.866 ± 0.05	2.946GluThr: 2.946 ± 0.044	3.442GluVal: 3.442 ± 0.05	0.745GluTrp: 0.745 ± 0.021	1.491GluTyr: 1.491 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.655PheAla: 3.655 ± 0.047	0.655PheCys: 0.655 ± 0.024	2.254PheAsp: 2.254 ± 0.046	1.677PheGlu: 1.677 ± 0.038	1.704PhePhe: 1.704 ± 0.043	2.994PheGly: 2.994 ± 0.059	0.847PheHis: 0.847 ± 0.028	2.611PheIle: 2.611 ± 0.047	1.234PheLys: 1.234 ± 0.031	3.369PheLeu: 3.369 ± 0.056	1.078PheMet: 1.078 ± 0.03	1.697PheAsn: 1.697 ± 0.037	1.532PhePro: 1.532 ± 0.039	1.06PheGln: 1.06 ± 0.027	2.007PheArg: 2.007 ± 0.04	3.133PheSer: 3.133 ± 0.053	2.616PheThr: 2.616 ± 0.057	2.447PheVal: 2.447 ± 0.048	0.659PheTrp: 0.659 ± 0.024	1.282PheTyr: 1.282 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	6.384GlyAla: 6.384 ± 0.083	1.13GlyCys: 1.13 ± 0.033	3.8GlyAsp: 3.8 ± 0.065	4.372GlyGlu: 4.372 ± 0.06	3.171GlyPhe: 3.171 ± 0.048	5.553GlyGly: 5.553 ± 0.085	1.69GlyHis: 1.69 ± 0.038	5.005GlyIle: 5.005 ± 0.062	3.926GlyLys: 3.926 ± 0.063	7.13GlyLeu: 7.13 ± 0.093	2.528GlyMet: 2.528 ± 0.046	2.912GlyAsn: 2.912 ± 0.065	2.044GlyPro: 2.044 ± 0.04	2.838GlyGln: 2.838 ± 0.049	4.158GlyArg: 4.158 ± 0.064	4.073GlySer: 4.073 ± 0.059	3.827GlyThr: 3.827 ± 0.075	5.838GlyVal: 5.838 ± 0.087	1.358GlyTrp: 1.358 ± 0.04	2.657GlyTyr: 2.657 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.901HisAla: 1.901 ± 0.043	0.401HisCys: 0.401 ± 0.019	1.197HisAsp: 1.197 ± 0.036	1.128HisGlu: 1.128 ± 0.031	1.094HisPhe: 1.094 ± 0.032	1.716HisGly: 1.716 ± 0.041	0.841HisHis: 0.841 ± 0.031	1.374HisIle: 1.374 ± 0.033	0.769HisLys: 0.769 ± 0.024	2.3HisLeu: 2.3 ± 0.046	0.598HisMet: 0.598 ± 0.023	0.873HisAsn: 0.873 ± 0.026	1.36HisPro: 1.36 ± 0.031	1.149HisGln: 1.149 ± 0.032	1.426HisArg: 1.426 ± 0.036	1.297HisSer: 1.297 ± 0.036	1.119HisThr: 1.119 ± 0.028	1.38HisVal: 1.38 ± 0.033	0.416HisTrp: 0.416 ± 0.017	1.006HisTyr: 1.006 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	6.354IleAla: 6.354 ± 0.082	0.76IleCys: 0.76 ± 0.026	3.463IleAsp: 3.463 ± 0.065	3.13IleGlu: 3.13 ± 0.053	2.177IlePhe: 2.177 ± 0.055	4.487IleGly: 4.487 ± 0.065	1.239IleHis: 1.239 ± 0.031	3.546IleIle: 3.546 ± 0.064	2.329IleLys: 2.329 ± 0.048	5.069IleLeu: 5.069 ± 0.07	1.361IleMet: 1.361 ± 0.035	2.687IleAsn: 2.687 ± 0.047	2.776IlePro: 2.776 ± 0.046	1.868IleGln: 1.868 ± 0.04	3.114IleArg: 3.114 ± 0.055	3.864IleSer: 3.864 ± 0.061	3.706IleThr: 3.706 ± 0.064	4.023IleVal: 4.023 ± 0.064	0.773IleTrp: 0.773 ± 0.027	1.601IleTyr: 1.601 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.172LysAla: 4.172 ± 0.062	0.342LysCys: 0.342 ± 0.017	1.942LysAsp: 1.942 ± 0.036	2.418LysGlu: 2.418 ± 0.05	1.145LysPhe: 1.145 ± 0.035	2.917LysGly: 2.917 ± 0.049	0.865LysHis: 0.865 ± 0.024	2.353LysIle: 2.353 ± 0.051	2.332LysLys: 2.332 ± 0.047	4.042LysLeu: 4.042 ± 0.058	1.311LysMet: 1.311 ± 0.033	1.869LysAsn: 1.869 ± 0.04	2.182LysPro: 2.182 ± 0.047	1.81LysGln: 1.81 ± 0.043	2.768LysArg: 2.768 ± 0.05	2.365LysSer: 2.365 ± 0.041	2.683LysThr: 2.683 ± 0.051	2.795LysVal: 2.795 ± 0.046	0.475LysTrp: 0.475 ± 0.021	1.19LysTyr: 1.19 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	11.007LeuAla: 11.007 ± 0.106	1.388LeuCys: 1.388 ± 0.04	5.098LeuAsp: 5.098 ± 0.069	5.144LeuGlu: 5.144 ± 0.071	4.165LeuPhe: 4.165 ± 0.07	6.94LeuGly: 6.94 ± 0.089	2.322LeuHis: 2.322 ± 0.05	5.737LeuIle: 5.737 ± 0.075	4.422LeuLys: 4.422 ± 0.069	11.509LeuLeu: 11.509 ± 0.137	2.968LeuMet: 2.968 ± 0.057	4.244LeuAsn: 4.244 ± 0.063	5.789LeuPro: 5.789 ± 0.077	3.949LeuGln: 3.949 ± 0.059	6.192LeuArg: 6.192 ± 0.068	7.205LeuSer: 7.205 ± 0.094	6.53LeuThr: 6.53 ± 0.07	6.701LeuVal: 6.701 ± 0.082	1.478LeuTrp: 1.478 ± 0.036	2.658LeuTyr: 2.658 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	3.05MetAla: 3.05 ± 0.049	0.248MetCys: 0.248 ± 0.014	1.218MetAsp: 1.218 ± 0.031	1.28MetGlu: 1.28 ± 0.028	0.948MetPhe: 0.948 ± 0.027	2.027MetGly: 2.027 ± 0.042	0.537MetHis: 0.537 ± 0.019	1.584MetIle: 1.584 ± 0.038	1.462MetLys: 1.462 ± 0.028	3.253MetLeu: 3.253 ± 0.055	0.889MetMet: 0.889 ± 0.027	1.157MetAsn: 1.157 ± 0.034	1.56MetPro: 1.56 ± 0.039	1.253MetGln: 1.253 ± 0.036	1.651MetArg: 1.651 ± 0.039	1.914MetSer: 1.914 ± 0.042	1.892MetThr: 1.892 ± 0.044	2.115MetVal: 2.115 ± 0.045	0.295MetTrp: 0.295 ± 0.016	0.554MetTyr: 0.554 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.754AsnAla: 3.754 ± 0.059	0.392AsnCys: 0.392 ± 0.018	2.146AsnAsp: 2.146 ± 0.05	1.937AsnGlu: 1.937 ± 0.044	1.289AsnPhe: 1.289 ± 0.036	3.149AsnGly: 3.149 ± 0.057	0.914AsnHis: 0.914 ± 0.03	2.408AsnIle: 2.408 ± 0.056	1.577AsnLys: 1.577 ± 0.038	3.421AsnLeu: 3.421 ± 0.061	0.975AsnMet: 0.975 ± 0.026	1.636AsnAsn: 1.636 ± 0.047	2.077AsnPro: 2.077 ± 0.04	1.488AsnGln: 1.488 ± 0.032	2.118AsnArg: 2.118 ± 0.041	2.106AsnSer: 2.106 ± 0.042	2.169AsnThr: 2.169 ± 0.051	2.669AsnVal: 2.669 ± 0.047	0.62AsnTrp: 0.62 ± 0.027	1.234AsnTyr: 1.234 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	4.732ProAla: 4.732 ± 0.061	0.468ProCys: 0.468 ± 0.02	2.865ProAsp: 2.865 ± 0.052	3.229ProGlu: 3.229 ± 0.061	1.932ProPhe: 1.932 ± 0.039	3.762ProGly: 3.762 ± 0.055	1.073ProHis: 1.073 ± 0.033	1.856ProIle: 1.856 ± 0.04	1.47ProLys: 1.47 ± 0.03	5.144ProLeu: 5.144 ± 0.067	1.174ProMet: 1.174 ± 0.03	1.257ProAsn: 1.257 ± 0.032	1.858ProPro: 1.858 ± 0.044	2.188ProGln: 2.188 ± 0.045	2.192ProArg: 2.192 ± 0.041	2.199ProSer: 2.199 ± 0.036	2.198ProThr: 2.198 ± 0.048	4.036ProVal: 4.036 ± 0.067	0.755ProTrp: 0.755 ± 0.025	1.305ProTyr: 1.305 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.369GlnAla: 4.369 ± 0.065	0.439GlnCys: 0.439 ± 0.02	1.73GlnAsp: 1.73 ± 0.04	2.219GlnGlu: 2.219 ± 0.048	1.462GlnPhe: 1.462 ± 0.034	2.877GlnGly: 2.877 ± 0.056	1.262GlnHis: 1.262 ± 0.032	2.202GlnIle: 2.202 ± 0.047	1.776GlnLys: 1.776 ± 0.043	4.661GlnLeu: 4.661 ± 0.07	1.204GlnMet: 1.204 ± 0.029	1.493GlnAsn: 1.493 ± 0.042	2.145GlnPro: 2.145 ± 0.051	2.964GlnGln: 2.964 ± 0.066	3.07GlnArg: 3.07 ± 0.052	2.258GlnSer: 2.258 ± 0.042	2.25GlnThr: 2.25 ± 0.046	2.681GlnVal: 2.681 ± 0.053	0.694GlnTrp: 0.694 ± 0.025	1.236GlnTyr: 1.236 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	4.615ArgAla: 4.615 ± 0.073	0.901ArgCys: 0.901 ± 0.028	3.009ArgAsp: 3.009 ± 0.063	3.752ArgGlu: 3.752 ± 0.065	2.7ArgPhe: 2.7 ± 0.047	3.554ArgGly: 3.554 ± 0.056	1.809ArgHis: 1.809 ± 0.041	3.435ArgIle: 3.435 ± 0.052	2.48ArgLys: 2.48 ± 0.048	6.642ArgLeu: 6.642 ± 0.086	1.937ArgMet: 1.937 ± 0.035	2.093ArgAsn: 2.093 ± 0.047	2.428ArgPro: 2.428 ± 0.045	3.205ArgGln: 3.205 ± 0.056	4.354ArgArg: 4.354 ± 0.075	3.029ArgSer: 3.029 ± 0.05	2.668ArgThr: 2.668 ± 0.059	3.785ArgVal: 3.785 ± 0.054	1.107ArgTrp: 1.107 ± 0.027	2.402ArgTyr: 2.402 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.687SerAla: 5.687 ± 0.07	0.656SerCys: 0.656 ± 0.026	3.04SerAsp: 3.04 ± 0.054	3.013SerGlu: 3.013 ± 0.053	2.278SerPhe: 2.278 ± 0.041	5.44SerGly: 5.44 ± 0.068	1.431SerHis: 1.431 ± 0.032	3.068SerIle: 3.068 ± 0.049	1.955SerLys: 1.955 ± 0.04	6.573SerLeu: 6.573 ± 0.078	1.565SerMet: 1.565 ± 0.038	1.847SerAsn: 1.847 ± 0.041	2.791SerPro: 2.791 ± 0.052	2.478SerGln: 2.478 ± 0.044	3.662SerArg: 3.662 ± 0.058	3.509SerSer: 3.509 ± 0.06	3.027SerThr: 3.027 ± 0.055	4.284SerVal: 4.284 ± 0.058	0.999SerTrp: 0.999 ± 0.03	1.641SerTyr: 1.641 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.178ThrAla: 5.178 ± 0.071	0.615ThrCys: 0.615 ± 0.024	2.757ThrAsp: 2.757 ± 0.056	2.544ThrGlu: 2.544 ± 0.049	2.124ThrPhe: 2.124 ± 0.044	4.759ThrGly: 4.759 ± 0.065	1.302ThrHis: 1.302 ± 0.033	3.152ThrIle: 3.152 ± 0.06	1.536ThrLys: 1.536 ± 0.037	7.536ThrLeu: 7.536 ± 0.087	1.243ThrMet: 1.243 ± 0.033	1.65ThrAsn: 1.65 ± 0.044	3.395ThrPro: 3.395 ± 0.052	2.245ThrGln: 2.245 ± 0.046	3.101ThrArg: 3.101 ± 0.052	2.907ThrSer: 2.907 ± 0.053	3.043ThrThr: 3.043 ± 0.053	4.103ThrVal: 4.103 ± 0.08	0.888ThrTrp: 0.888 ± 0.028	1.284ThrTyr: 1.284 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	6.722ValAla: 6.722 ± 0.086	0.898ValCys: 0.898 ± 0.028	3.666ValAsp: 3.666 ± 0.063	3.793ValGlu: 3.793 ± 0.057	2.544ValPhe: 2.544 ± 0.05	4.715ValGly: 4.715 ± 0.068	1.247ValHis: 1.247 ± 0.03	4.542ValIle: 4.542 ± 0.066	3.095ValLys: 3.095 ± 0.057	7.055ValLeu: 7.055 ± 0.082	2.246ValMet: 2.246 ± 0.046	2.848ValAsn: 2.848 ± 0.059	3.033ValPro: 3.033 ± 0.054	2.268ValGln: 2.268 ± 0.044	3.73ValArg: 3.73 ± 0.059	4.442ValSer: 4.442 ± 0.06	4.301ValThr: 4.301 ± 0.081	5.392ValVal: 5.392 ± 0.079	1.044ValTrp: 1.044 ± 0.03	1.791ValTyr: 1.791 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.073TrpAla: 1.073 ± 0.03	0.239TrpCys: 0.239 ± 0.014	0.641TrpAsp: 0.641 ± 0.023	0.579TrpGlu: 0.579 ± 0.022	0.689TrpPhe: 0.689 ± 0.024	0.915TrpGly: 0.915 ± 0.026	0.468TrpHis: 0.468 ± 0.018	0.785TrpIle: 0.785 ± 0.025	0.573TrpLys: 0.573 ± 0.022	2.324TrpLeu: 2.324 ± 0.046	0.532TrpMet: 0.532 ± 0.021	0.502TrpAsn: 0.502 ± 0.022	0.73TrpPro: 0.73 ± 0.024	1.163TrpGln: 1.163 ± 0.033	1.419TrpArg: 1.419 ± 0.04	0.865TrpSer: 0.865 ± 0.027	0.631TrpThr: 0.631 ± 0.026	0.929TrpVal: 0.929 ± 0.03	0.271TrpTrp: 0.271 ± 0.016	0.467TrpTyr: 0.467 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.552TyrAla: 2.552 ± 0.045	0.458TyrCys: 0.458 ± 0.018	1.601TyrAsp: 1.601 ± 0.046	1.237TyrGlu: 1.237 ± 0.032	1.212TyrPhe: 1.212 ± 0.031	2.278TyrGly: 2.278 ± 0.049	0.778TyrHis: 0.778 ± 0.025	1.443TyrIle: 1.443 ± 0.038	1.0TyrLys: 1.0 ± 0.028	3.023TyrLeu: 3.023 ± 0.056	0.723TyrMet: 0.723 ± 0.024	1.105TyrAsn: 1.105 ± 0.034	1.445TyrPro: 1.445 ± 0.037	1.59TyrGln: 1.59 ± 0.037	2.057TyrArg: 2.057 ± 0.041	1.818TyrSer: 1.818 ± 0.038	1.557TyrThr: 1.557 ± 0.042	1.664TyrVal: 1.664 ± 0.037	0.476TyrTrp: 0.476 ± 0.02	1.013TyrTyr: 1.013 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6192 proteins (1208264 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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