Amino acid dipepetide frequency for Sheep polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.429AlaAla: 5.429 ± 3.258
0.0AlaCys: 0.0 ± 0.0
3.455AlaAsp: 3.455 ± 0.63
4.936AlaGlu: 4.936 ± 1.87
2.962AlaPhe: 2.962 ± 1.19
4.442AlaGly: 4.442 ± 1.277
2.962AlaHis: 2.962 ± 1.904
4.442AlaIle: 4.442 ± 0.985
1.974AlaLys: 1.974 ± 1.09
6.91AlaLeu: 6.91 ± 1.811
1.481AlaMet: 1.481 ± 0.987
1.481AlaAsn: 1.481 ± 0.772
5.923AlaPro: 5.923 ± 1.519
4.442AlaGln: 4.442 ± 0.444
5.923AlaArg: 5.923 ± 2.1
6.417AlaSer: 6.417 ± 1.811
4.442AlaThr: 4.442 ± 1.007
3.949AlaVal: 3.949 ± 1.097
0.987AlaTrp: 0.987 ± 0.443
2.468AlaTyr: 2.468 ± 1.259
0.0AlaXaa: 0.0 ± 0.0
Cys
0.494CysAla: 0.494 ± 0.441
0.494CysCys: 0.494 ± 0.398
0.987CysAsp: 0.987 ± 0.443
0.494CysGlu: 0.494 ± 0.398
0.987CysPhe: 0.987 ± 0.565
0.494CysGly: 0.494 ± 0.398
0.0CysHis: 0.0 ± 0.0
0.494CysIle: 0.494 ± 0.398
2.962CysLys: 2.962 ± 0.854
1.974CysLeu: 1.974 ± 1.739
0.0CysMet: 0.0 ± 0.0
0.987CysAsn: 0.987 ± 0.796
0.987CysPro: 0.987 ± 0.835
0.987CysGln: 0.987 ± 0.565
0.494CysArg: 0.494 ± 0.441
2.468CysSer: 2.468 ± 1.146
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.494CysTrp: 0.494 ± 0.6
1.481CysTyr: 1.481 ± 1.273
0.0CysXaa: 0.0 ± 0.0
Asp
3.455AspAla: 3.455 ± 0.908
0.494AspCys: 0.494 ± 0.6
0.987AspAsp: 0.987 ± 0.443
0.494AspGlu: 0.494 ± 0.441
0.987AspPhe: 0.987 ± 0.882
5.923AspGly: 5.923 ± 1.724
0.494AspHis: 0.494 ± 0.398
3.455AspIle: 3.455 ± 1.868
1.974AspLys: 1.974 ± 1.09
8.391AspLeu: 8.391 ± 2.538
1.974AspMet: 1.974 ± 0.877
0.987AspAsn: 0.987 ± 0.443
1.974AspPro: 1.974 ± 1.2
2.962AspGln: 2.962 ± 0.776
2.962AspArg: 2.962 ± 0.495
1.481AspSer: 1.481 ± 0.717
2.468AspThr: 2.468 ± 0.682
1.481AspVal: 1.481 ± 1.194
0.494AspTrp: 0.494 ± 0.6
2.468AspTyr: 2.468 ± 1.115
0.0AspXaa: 0.0 ± 0.0
Glu
8.885GluAla: 8.885 ± 2.038
0.987GluCys: 0.987 ± 0.521
4.442GluAsp: 4.442 ± 0.864
11.352GluGlu: 11.352 ± 2.233
1.974GluPhe: 1.974 ± 1.09
2.468GluGly: 2.468 ± 1.442
0.0GluHis: 0.0 ± 0.0
2.468GluIle: 2.468 ± 0.778
1.974GluLys: 1.974 ± 1.114
7.404GluLeu: 7.404 ± 2.258
1.481GluMet: 1.481 ± 1.194
4.442GluAsn: 4.442 ± 1.192
1.481GluPro: 1.481 ± 0.559
0.987GluGln: 0.987 ± 1.068
1.481GluArg: 1.481 ± 0.978
2.962GluSer: 2.962 ± 1.322
1.481GluThr: 1.481 ± 0.758
5.429GluVal: 5.429 ± 1.502
1.974GluTrp: 1.974 ± 0.715
1.974GluTyr: 1.974 ± 0.685
0.0GluXaa: 0.0 ± 0.0
Phe
2.962PheAla: 2.962 ± 0.784
0.987PheCys: 0.987 ± 0.796
0.494PheAsp: 0.494 ± 0.441
2.962PheGlu: 2.962 ± 1.088
0.494PhePhe: 0.494 ± 0.441
2.468PheGly: 2.468 ± 1.256
0.987PheHis: 0.987 ± 0.635
0.987PheIle: 0.987 ± 0.635
2.468PheLys: 2.468 ± 0.735
3.455PheLeu: 3.455 ± 1.391
1.481PheMet: 1.481 ± 0.717
1.481PheAsn: 1.481 ± 0.477
3.949PhePro: 3.949 ± 0.863
0.494PheGln: 0.494 ± 0.398
2.468PheArg: 2.468 ± 1.256
2.962PheSer: 2.962 ± 1.137
2.962PheThr: 2.962 ± 1.002
0.494PheVal: 0.494 ± 0.398
1.481PheTrp: 1.481 ± 0.696
0.494PheTyr: 0.494 ± 0.441
0.0PheXaa: 0.0 ± 0.0
Gly
3.455GlyAla: 3.455 ± 1.626
0.494GlyCys: 0.494 ± 0.398
4.442GlyAsp: 4.442 ± 0.932
2.962GlyGlu: 2.962 ± 1.523
0.987GlyPhe: 0.987 ± 0.882
6.91GlyGly: 6.91 ± 0.604
0.987GlyHis: 0.987 ± 0.521
2.962GlyIle: 2.962 ± 0.785
0.987GlyLys: 0.987 ± 0.796
7.404GlyLeu: 7.404 ± 1.078
1.481GlyMet: 1.481 ± 0.698
2.962GlyAsn: 2.962 ± 1.593
3.455GlyPro: 3.455 ± 1.151
4.936GlyGln: 4.936 ± 1.731
2.962GlyArg: 2.962 ± 1.519
2.962GlySer: 2.962 ± 0.808
3.949GlyThr: 3.949 ± 1.144
5.923GlyVal: 5.923 ± 2.086
0.0GlyTrp: 0.0 ± 0.0
1.481GlyTyr: 1.481 ± 0.477
0.0GlyXaa: 0.0 ± 0.0
His
0.494HisAla: 0.494 ± 0.398
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.494HisPhe: 0.494 ± 0.398
0.987HisGly: 0.987 ± 0.815
0.494HisHis: 0.494 ± 0.398
0.987HisIle: 0.987 ± 0.465
0.494HisLys: 0.494 ± 0.827
4.442HisLeu: 4.442 ± 0.875
0.987HisMet: 0.987 ± 0.443
0.494HisAsn: 0.494 ± 0.441
1.481HisPro: 1.481 ± 0.772
0.987HisGln: 0.987 ± 0.635
6.417HisArg: 6.417 ± 1.69
2.962HisSer: 2.962 ± 0.985
0.494HisThr: 0.494 ± 0.434
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.494HisTyr: 0.494 ± 0.6
0.0HisXaa: 0.0 ± 0.0
Ile
2.962IleAla: 2.962 ± 1.414
0.494IleCys: 0.494 ± 0.398
1.481IleAsp: 1.481 ± 1.194
2.468IleGlu: 2.468 ± 0.736
0.494IlePhe: 0.494 ± 0.398
0.987IleGly: 0.987 ± 0.882
0.0IleHis: 0.0 ± 0.0
0.494IleIle: 0.494 ± 0.434
3.455IleLys: 3.455 ± 1.385
2.468IleLeu: 2.468 ± 0.97
0.987IleMet: 0.987 ± 0.494
2.962IleAsn: 2.962 ± 1.092
3.455IlePro: 3.455 ± 1.348
1.974IleGln: 1.974 ± 0.715
0.494IleArg: 0.494 ± 0.827
5.429IleSer: 5.429 ± 2.061
1.974IleThr: 1.974 ± 0.475
3.455IleVal: 3.455 ± 0.809
0.0IleTrp: 0.0 ± 0.0
0.987IleTyr: 0.987 ± 0.565
0.0IleXaa: 0.0 ± 0.0
Lys
4.442LysAla: 4.442 ± 1.933
0.987LysCys: 0.987 ± 0.565
1.481LysAsp: 1.481 ± 0.696
2.962LysGlu: 2.962 ± 1.243
1.481LysPhe: 1.481 ± 0.98
5.923LysGly: 5.923 ± 1.786
1.481LysHis: 1.481 ± 1.194
0.494LysIle: 0.494 ± 0.398
4.936LysLys: 4.936 ± 0.812
4.936LysLeu: 4.936 ± 2.406
0.987LysMet: 0.987 ± 0.443
1.974LysAsn: 1.974 ± 1.2
1.481LysPro: 1.481 ± 0.97
3.455LysGln: 3.455 ± 0.807
4.936LysArg: 4.936 ± 1.736
0.987LysSer: 0.987 ± 0.796
1.974LysThr: 1.974 ± 1.255
1.974LysVal: 1.974 ± 1.105
0.0LysTrp: 0.0 ± 0.0
0.987LysTyr: 0.987 ± 0.521
0.0LysXaa: 0.0 ± 0.0
Leu
8.391LeuAla: 8.391 ± 1.956
1.974LeuCys: 1.974 ± 0.685
7.897LeuAsp: 7.897 ± 1.62
6.91LeuGlu: 6.91 ± 2.668
6.417LeuPhe: 6.417 ± 1.809
2.468LeuGly: 2.468 ± 0.545
1.974LeuHis: 1.974 ± 1.35
3.455LeuIle: 3.455 ± 0.738
2.962LeuLys: 2.962 ± 1.386
10.365LeuLeu: 10.365 ± 2.045
5.429LeuMet: 5.429 ± 2.092
6.91LeuAsn: 6.91 ± 1.468
8.391LeuPro: 8.391 ± 1.111
5.429LeuGln: 5.429 ± 1.103
4.936LeuArg: 4.936 ± 1.987
4.936LeuSer: 4.936 ± 1.488
3.455LeuThr: 3.455 ± 1.275
1.974LeuVal: 1.974 ± 0.653
0.987LeuTrp: 0.987 ± 0.835
6.417LeuTyr: 6.417 ± 1.813
0.0LeuXaa: 0.0 ± 0.0
Met
1.974MetAla: 1.974 ± 0.475
0.987MetCys: 0.987 ± 0.565
0.987MetAsp: 0.987 ± 0.565
1.974MetGlu: 1.974 ± 1.09
1.481MetPhe: 1.481 ± 0.717
2.468MetGly: 2.468 ± 1.191
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
3.455MetLys: 3.455 ± 1.572
4.936MetLeu: 4.936 ± 1.426
1.481MetMet: 1.481 ± 0.57
0.987MetAsn: 0.987 ± 0.521
1.481MetPro: 1.481 ± 0.546
0.987MetGln: 0.987 ± 0.882
1.974MetArg: 1.974 ± 0.685
1.974MetSer: 1.974 ± 0.685
0.494MetThr: 0.494 ± 0.441
1.974MetVal: 1.974 ± 1.005
1.481MetTrp: 1.481 ± 0.698
0.494MetTyr: 0.494 ± 0.398
0.0MetXaa: 0.0 ± 0.0
Asn
1.974AsnAla: 1.974 ± 0.715
0.494AsnCys: 0.494 ± 0.534
0.494AsnAsp: 0.494 ± 0.441
2.468AsnGlu: 2.468 ± 1.123
0.494AsnPhe: 0.494 ± 0.398
0.494AsnGly: 0.494 ± 0.441
1.481AsnHis: 1.481 ± 0.717
2.468AsnIle: 2.468 ± 1.448
3.455AsnLys: 3.455 ± 1.145
4.442AsnLeu: 4.442 ± 1.574
2.468AsnMet: 2.468 ± 1.177
0.0AsnAsn: 0.0 ± 0.0
3.949AsnPro: 3.949 ± 1.726
1.974AsnGln: 1.974 ± 0.685
0.987AsnArg: 0.987 ± 0.565
1.974AsnSer: 1.974 ± 1.629
3.455AsnThr: 3.455 ± 1.63
3.455AsnVal: 3.455 ± 1.669
2.468AsnTrp: 2.468 ± 1.345
2.962AsnTyr: 2.962 ± 0.901
0.0AsnXaa: 0.0 ± 0.0
Pro
4.442ProAla: 4.442 ± 1.387
0.987ProCys: 0.987 ± 0.74
3.949ProAsp: 3.949 ± 1.156
1.481ProGlu: 1.481 ± 1.194
1.974ProPhe: 1.974 ± 0.685
4.936ProGly: 4.936 ± 1.137
0.494ProHis: 0.494 ± 0.434
1.481ProIle: 1.481 ± 0.546
3.455ProLys: 3.455 ± 0.809
5.429ProLeu: 5.429 ± 1.429
0.987ProMet: 0.987 ± 0.882
3.949ProAsn: 3.949 ± 0.867
6.91ProPro: 6.91 ± 2.316
5.923ProGln: 5.923 ± 2.1
5.429ProArg: 5.429 ± 1.524
2.962ProSer: 2.962 ± 1.563
4.442ProThr: 4.442 ± 0.804
5.429ProVal: 5.429 ± 1.537
0.494ProTrp: 0.494 ± 0.441
1.974ProTyr: 1.974 ± 0.475
0.0ProXaa: 0.0 ± 0.0
Gln
2.962GlnAla: 2.962 ± 1.414
0.494GlnCys: 0.494 ± 0.534
1.481GlnAsp: 1.481 ± 0.559
4.442GlnGlu: 4.442 ± 1.188
1.974GlnPhe: 1.974 ± 1.2
2.468GlnGly: 2.468 ± 1.123
0.494GlnHis: 0.494 ± 0.441
1.481GlnIle: 1.481 ± 0.546
2.468GlnLys: 2.468 ± 0.53
4.442GlnLeu: 4.442 ± 1.776
1.974GlnMet: 1.974 ± 1.09
0.987GlnAsn: 0.987 ± 0.443
5.429GlnPro: 5.429 ± 1.606
2.468GlnGln: 2.468 ± 1.115
4.936GlnArg: 4.936 ± 3.174
3.949GlnSer: 3.949 ± 1.173
4.442GlnThr: 4.442 ± 2.499
2.468GlnVal: 2.468 ± 1.099
0.0GlnTrp: 0.0 ± 0.0
0.987GlnTyr: 0.987 ± 0.443
0.0GlnXaa: 0.0 ± 0.0
Arg
5.429ArgAla: 5.429 ± 2.557
1.481ArgCys: 1.481 ± 0.94
3.455ArgAsp: 3.455 ± 1.043
6.417ArgGlu: 6.417 ± 1.557
2.468ArgPhe: 2.468 ± 0.53
1.481ArgGly: 1.481 ± 0.789
2.962ArgHis: 2.962 ± 1.519
1.974ArgIle: 1.974 ± 0.884
1.481ArgLys: 1.481 ± 0.559
1.481ArgLeu: 1.481 ± 0.772
1.481ArgMet: 1.481 ± 0.698
1.481ArgAsn: 1.481 ± 1.497
1.974ArgPro: 1.974 ± 1.185
2.962ArgGln: 2.962 ± 1.904
4.936ArgArg: 4.936 ± 1.197
5.923ArgSer: 5.923 ± 2.324
3.949ArgThr: 3.949 ± 0.743
5.429ArgVal: 5.429 ± 1.166
1.481ArgTrp: 1.481 ± 0.987
4.936ArgTyr: 4.936 ± 1.687
0.0ArgXaa: 0.0 ± 0.0
Ser
7.404SerAla: 7.404 ± 2.618
2.468SerCys: 2.468 ± 0.97
3.949SerAsp: 3.949 ± 1.704
3.455SerGlu: 3.455 ± 2.226
1.974SerPhe: 1.974 ± 0.643
2.962SerGly: 2.962 ± 1.136
3.455SerHis: 3.455 ± 1.108
3.949SerIle: 3.949 ± 0.446
2.468SerLys: 2.468 ± 1.46
7.404SerLeu: 7.404 ± 0.503
0.987SerMet: 0.987 ± 0.989
2.468SerAsn: 2.468 ± 0.958
3.455SerPro: 3.455 ± 1.208
4.442SerGln: 4.442 ± 0.742
2.468SerArg: 2.468 ± 1.02
2.468SerSer: 2.468 ± 1.586
2.962SerThr: 2.962 ± 0.859
2.962SerVal: 2.962 ± 1.686
1.974SerTrp: 1.974 ± 1.09
0.987SerTyr: 0.987 ± 0.815
0.0SerXaa: 0.0 ± 0.0
Thr
3.949ThrAla: 3.949 ± 1.312
1.481ThrCys: 1.481 ± 1.203
1.481ThrAsp: 1.481 ± 0.803
2.468ThrGlu: 2.468 ± 1.005
0.987ThrPhe: 0.987 ± 0.443
4.442ThrGly: 4.442 ± 1.054
2.468ThrHis: 2.468 ± 0.852
0.987ThrIle: 0.987 ± 0.882
0.494ThrLys: 0.494 ± 0.534
6.417ThrLeu: 6.417 ± 1.314
1.974ThrMet: 1.974 ± 1.09
2.468ThrAsn: 2.468 ± 1.201
6.417ThrPro: 6.417 ± 1.261
3.455ThrGln: 3.455 ± 1.242
1.481ThrArg: 1.481 ± 0.698
0.494ThrSer: 0.494 ± 0.398
7.404ThrThr: 7.404 ± 2.87
5.429ThrVal: 5.429 ± 2.091
1.481ThrTrp: 1.481 ± 0.879
0.987ThrTyr: 0.987 ± 0.598
0.0ThrXaa: 0.0 ± 0.0
Val
3.455ValAla: 3.455 ± 1.208
0.494ValCys: 0.494 ± 0.6
1.481ValAsp: 1.481 ± 0.696
3.455ValGlu: 3.455 ± 1.627
2.962ValPhe: 2.962 ± 1.136
5.429ValGly: 5.429 ± 1.636
0.987ValHis: 0.987 ± 0.443
1.481ValIle: 1.481 ± 0.717
4.442ValLys: 4.442 ± 0.963
5.429ValLeu: 5.429 ± 1.247
1.974ValMet: 1.974 ± 0.685
2.962ValAsn: 2.962 ± 0.808
2.962ValPro: 2.962 ± 1.386
0.494ValGln: 0.494 ± 0.398
1.974ValArg: 1.974 ± 1.765
6.91ValSer: 6.91 ± 0.808
3.455ValThr: 3.455 ± 0.946
3.949ValVal: 3.949 ± 0.863
0.494ValTrp: 0.494 ± 0.6
3.455ValTyr: 3.455 ± 0.839
0.0ValXaa: 0.0 ± 0.0
Trp
1.974TrpAla: 1.974 ± 1.269
0.0TrpCys: 0.0 ± 0.0
0.987TrpAsp: 0.987 ± 0.635
1.974TrpGlu: 1.974 ± 0.677
1.481TrpPhe: 1.481 ± 0.879
0.494TrpGly: 0.494 ± 0.441
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.481TrpLys: 1.481 ± 0.717
1.974TrpLeu: 1.974 ± 0.768
0.987TrpMet: 0.987 ± 0.635
0.987TrpAsn: 0.987 ± 0.565
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.987TrpArg: 0.987 ± 1.05
1.481TrpSer: 1.481 ± 0.696
0.494TrpThr: 0.494 ± 0.6
1.481TrpVal: 1.481 ± 0.879
0.494TrpTrp: 0.494 ± 0.398
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.494TyrAla: 0.494 ± 0.398
1.481TyrCys: 1.481 ± 0.772
1.974TyrAsp: 1.974 ± 1.131
1.974TyrGlu: 1.974 ± 0.475
3.455TyrPhe: 3.455 ± 0.946
3.455TyrGly: 3.455 ± 0.681
0.987TyrHis: 0.987 ± 0.905
2.962TyrIle: 2.962 ± 1.194
0.494TyrLys: 0.494 ± 0.434
1.974TyrLeu: 1.974 ± 0.475
0.494TyrMet: 0.494 ± 0.398
0.987TyrAsn: 0.987 ± 0.796
1.974TyrPro: 1.974 ± 0.98
0.987TyrGln: 0.987 ± 0.443
4.936TyrArg: 4.936 ± 1.548
3.455TyrSer: 3.455 ± 0.964
2.468TyrThr: 2.468 ± 0.53
0.987TyrVal: 0.987 ± 0.796
0.494TyrTrp: 0.494 ± 0.398
1.481TyrTyr: 1.481 ± 0.546
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2027 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski