Amino acid dipepetide frequency for Tortoise microvirus 20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.632AlaAla: 0.632 ± 0.487
0.632AlaCys: 0.632 ± 0.487
2.528AlaAsp: 2.528 ± 0.943
4.425AlaGlu: 4.425 ± 1.612
1.264AlaPhe: 1.264 ± 0.973
6.953AlaGly: 6.953 ± 3.013
2.528AlaHis: 2.528 ± 0.91
4.425AlaIle: 4.425 ± 0.949
8.217AlaLys: 8.217 ± 2.685
1.896AlaLeu: 1.896 ± 0.989
1.896AlaMet: 1.896 ± 1.585
2.528AlaAsn: 2.528 ± 0.659
3.793AlaPro: 3.793 ± 1.563
1.264AlaGln: 1.264 ± 1.269
3.793AlaArg: 3.793 ± 1.352
3.793AlaSer: 3.793 ± 1.385
6.953AlaThr: 6.953 ± 1.728
1.896AlaVal: 1.896 ± 1.46
1.264AlaTrp: 1.264 ± 0.835
3.793AlaTyr: 3.793 ± 1.824
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.264CysAsp: 1.264 ± 0.905
1.264CysGlu: 1.264 ± 0.827
0.0CysPhe: 0.0 ± 0.0
0.632CysGly: 0.632 ± 0.526
0.0CysHis: 0.0 ± 0.0
0.632CysIle: 0.632 ± 0.526
1.264CysLys: 1.264 ± 1.241
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.632CysPro: 0.632 ± 0.526
0.0CysGln: 0.0 ± 0.0
0.632CysArg: 0.632 ± 0.487
0.632CysSer: 0.632 ± 0.487
1.896CysThr: 1.896 ± 1.581
0.632CysVal: 0.632 ± 0.526
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.161AspAla: 3.161 ± 1.685
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
3.793AspGlu: 3.793 ± 1.819
1.264AspPhe: 1.264 ± 0.455
0.632AspGly: 0.632 ± 0.487
0.0AspHis: 0.0 ± 0.0
1.264AspIle: 1.264 ± 1.212
5.057AspLys: 5.057 ± 2.327
4.425AspLeu: 4.425 ± 1.298
0.632AspMet: 0.632 ± 0.806
5.057AspAsn: 5.057 ± 1.313
2.528AspPro: 2.528 ± 0.93
1.896AspGln: 1.896 ± 0.781
2.528AspArg: 2.528 ± 1.418
0.632AspSer: 0.632 ± 0.878
3.161AspThr: 3.161 ± 1.685
3.161AspVal: 3.161 ± 1.182
1.896AspTrp: 1.896 ± 0.781
3.161AspTyr: 3.161 ± 2.118
0.0AspXaa: 0.0 ± 0.0
Glu
7.585GluAla: 7.585 ± 1.068
1.264GluCys: 1.264 ± 1.656
3.793GluAsp: 3.793 ± 1.198
5.057GluGlu: 5.057 ± 1.472
4.425GluPhe: 4.425 ± 1.16
2.528GluGly: 2.528 ± 0.659
2.528GluHis: 2.528 ± 1.638
10.114GluIle: 10.114 ± 4.43
4.425GluLys: 4.425 ± 1.612
2.528GluLeu: 2.528 ± 1.407
3.161GluMet: 3.161 ± 0.845
5.057GluAsn: 5.057 ± 1.32
1.264GluPro: 1.264 ± 0.963
3.793GluGln: 3.793 ± 2.393
3.161GluArg: 3.161 ± 1.33
4.425GluSer: 4.425 ± 1.242
3.161GluThr: 3.161 ± 1.382
3.793GluVal: 3.793 ± 1.557
1.896GluTrp: 1.896 ± 1.208
2.528GluTyr: 2.528 ± 0.801
0.0GluXaa: 0.0 ± 0.0
Phe
0.632PheAla: 0.632 ± 0.526
1.264PheCys: 1.264 ± 0.455
0.632PheAsp: 0.632 ± 0.526
1.264PheGlu: 1.264 ± 0.973
1.264PhePhe: 1.264 ± 0.455
1.896PheGly: 1.896 ± 0.855
0.0PheHis: 0.0 ± 0.0
2.528PheIle: 2.528 ± 1.947
3.161PheLys: 3.161 ± 1.511
3.793PheLeu: 3.793 ± 0.73
1.264PheMet: 1.264 ± 0.476
3.793PheAsn: 3.793 ± 1.709
0.0PhePro: 0.0 ± 0.0
0.632PheGln: 0.632 ± 0.487
3.793PheArg: 3.793 ± 1.025
1.896PheSer: 1.896 ± 0.781
1.264PheThr: 1.264 ± 0.973
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.425GlyAla: 4.425 ± 2.442
0.0GlyCys: 0.0 ± 0.0
3.793GlyAsp: 3.793 ± 1.702
5.057GlyGlu: 5.057 ± 0.725
1.264GlyPhe: 1.264 ± 0.973
11.378GlyGly: 11.378 ± 7.887
2.528GlyHis: 2.528 ± 1.399
1.264GlyIle: 1.264 ± 0.963
3.161GlyLys: 3.161 ± 0.665
5.689GlyLeu: 5.689 ± 2.749
2.528GlyMet: 2.528 ± 0.867
2.528GlyAsn: 2.528 ± 0.813
0.632GlyPro: 0.632 ± 0.487
1.264GlyGln: 1.264 ± 0.973
3.161GlyArg: 3.161 ± 1.258
2.528GlySer: 2.528 ± 1.947
3.793GlyThr: 3.793 ± 1.352
4.425GlyVal: 4.425 ± 1.194
1.264GlyTrp: 1.264 ± 1.052
1.896GlyTyr: 1.896 ± 1.075
0.0GlyXaa: 0.0 ± 0.0
His
3.161HisAla: 3.161 ± 1.182
0.0HisCys: 0.0 ± 0.0
0.632HisAsp: 0.632 ± 0.814
1.264HisGlu: 1.264 ± 0.835
1.264HisPhe: 1.264 ± 0.827
1.264HisGly: 1.264 ± 0.839
0.0HisHis: 0.0 ± 0.0
1.896HisIle: 1.896 ± 0.855
4.425HisLys: 4.425 ± 1.836
0.632HisLeu: 0.632 ± 0.526
0.0HisMet: 0.0 ± 0.0
1.896HisAsn: 1.896 ± 0.64
0.632HisPro: 0.632 ± 0.526
0.0HisGln: 0.0 ± 0.0
1.264HisArg: 1.264 ± 0.973
0.0HisSer: 0.0 ± 0.0
1.896HisThr: 1.896 ± 1.212
0.632HisVal: 0.632 ± 0.878
1.264HisTrp: 1.264 ± 0.764
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.321IleAla: 6.321 ± 1.262
0.632IleCys: 0.632 ± 0.828
4.425IleAsp: 4.425 ± 1.166
7.585IleGlu: 7.585 ± 4.073
1.896IlePhe: 1.896 ± 1.188
4.425IleGly: 4.425 ± 1.478
1.896IleHis: 1.896 ± 0.855
9.482IleIle: 9.482 ± 4.741
8.217IleLys: 8.217 ± 4.01
6.953IleLeu: 6.953 ± 2.591
1.896IleMet: 1.896 ± 1.316
8.217IleAsn: 8.217 ± 1.846
2.528IlePro: 2.528 ± 1.344
6.321IleGln: 6.321 ± 1.579
1.264IleArg: 1.264 ± 0.973
0.632IleSer: 0.632 ± 0.487
5.689IleThr: 5.689 ± 1.491
3.161IleVal: 3.161 ± 1.488
0.632IleTrp: 0.632 ± 0.526
1.896IleTyr: 1.896 ± 1.148
0.0IleXaa: 0.0 ± 0.0
Lys
3.161LysAla: 3.161 ± 1.246
1.264LysCys: 1.264 ± 1.036
6.321LysAsp: 6.321 ± 1.395
6.953LysGlu: 6.953 ± 3.064
1.896LysPhe: 1.896 ± 1.363
3.793LysGly: 3.793 ± 2.625
1.896LysHis: 1.896 ± 0.74
13.274LysIle: 13.274 ± 4.763
10.114LysLys: 10.114 ± 3.976
5.689LysLeu: 5.689 ± 2.907
4.425LysMet: 4.425 ± 1.287
5.057LysAsn: 5.057 ± 1.019
3.161LysPro: 3.161 ± 1.511
5.057LysGln: 5.057 ± 1.32
3.161LysArg: 3.161 ± 1.6
5.689LysSer: 5.689 ± 1.217
5.689LysThr: 5.689 ± 3.278
1.896LysVal: 1.896 ± 0.781
1.264LysTrp: 1.264 ± 0.839
0.632LysTyr: 0.632 ± 0.526
0.0LysXaa: 0.0 ± 0.0
Leu
5.057LeuAla: 5.057 ± 1.774
0.632LeuCys: 0.632 ± 0.487
1.264LeuAsp: 1.264 ± 0.455
3.793LeuGlu: 3.793 ± 2.915
1.264LeuPhe: 1.264 ± 0.855
4.425LeuGly: 4.425 ± 2.442
0.632LeuHis: 0.632 ± 0.878
8.217LeuIle: 8.217 ± 1.486
6.321LeuLys: 6.321 ± 2.895
6.321LeuLeu: 6.321 ± 1.788
1.896LeuMet: 1.896 ± 1.944
5.057LeuAsn: 5.057 ± 2.486
4.425LeuPro: 4.425 ± 2.327
3.161LeuGln: 3.161 ± 1.706
2.528LeuArg: 2.528 ± 0.659
3.161LeuSer: 3.161 ± 1.854
6.321LeuThr: 6.321 ± 1.911
3.793LeuVal: 3.793 ± 0.835
1.264LeuTrp: 1.264 ± 0.455
0.632LeuTyr: 0.632 ± 0.487
0.0LeuXaa: 0.0 ± 0.0
Met
0.632MetAla: 0.632 ± 0.814
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
5.689MetGlu: 5.689 ± 1.983
1.896MetPhe: 1.896 ± 0.855
0.632MetGly: 0.632 ± 0.487
0.632MetHis: 0.632 ± 0.878
3.161MetIle: 3.161 ± 1.292
1.896MetLys: 1.896 ± 1.163
1.896MetLeu: 1.896 ± 1.502
1.264MetMet: 1.264 ± 1.162
0.0MetAsn: 0.0 ± 0.0
1.896MetPro: 1.896 ± 0.989
1.896MetGln: 1.896 ± 1.148
3.161MetArg: 3.161 ± 1.258
3.793MetSer: 3.793 ± 0.73
0.632MetThr: 0.632 ± 0.526
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.896MetTyr: 1.896 ± 1.181
0.0MetXaa: 0.0 ± 0.0
Asn
6.321AsnAla: 6.321 ± 1.788
0.632AsnCys: 0.632 ± 0.526
7.585AsnAsp: 7.585 ± 1.872
6.321AsnGlu: 6.321 ± 1.924
0.632AsnPhe: 0.632 ± 0.487
2.528AsnGly: 2.528 ± 1.171
0.632AsnHis: 0.632 ± 0.487
5.057AsnIle: 5.057 ± 1.327
6.953AsnLys: 6.953 ± 1.977
5.057AsnLeu: 5.057 ± 1.578
1.896AsnMet: 1.896 ± 0.714
6.321AsnAsn: 6.321 ± 2.02
2.528AsnPro: 2.528 ± 0.813
4.425AsnGln: 4.425 ± 1.567
2.528AsnArg: 2.528 ± 1.06
2.528AsnSer: 2.528 ± 0.659
6.953AsnThr: 6.953 ± 1.027
3.161AsnVal: 3.161 ± 2.433
2.528AsnTrp: 2.528 ± 1.094
1.896AsnTyr: 1.896 ± 1.46
0.0AsnXaa: 0.0 ± 0.0
Pro
5.689ProAla: 5.689 ± 2.119
0.0ProCys: 0.0 ± 0.0
0.632ProAsp: 0.632 ± 0.487
3.793ProGlu: 3.793 ± 1.358
0.632ProPhe: 0.632 ± 0.487
0.632ProGly: 0.632 ± 0.814
0.0ProHis: 0.0 ± 0.0
3.161ProIle: 3.161 ± 0.86
3.161ProLys: 3.161 ± 1.854
2.528ProLeu: 2.528 ± 1.844
1.896ProMet: 1.896 ± 0.588
4.425ProAsn: 4.425 ± 1.596
1.896ProPro: 1.896 ± 0.781
0.0ProGln: 0.0 ± 0.0
1.264ProArg: 1.264 ± 0.855
1.264ProSer: 1.264 ± 0.455
2.528ProThr: 2.528 ± 0.91
0.632ProVal: 0.632 ± 0.526
0.632ProTrp: 0.632 ± 0.487
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.896GlnAla: 1.896 ± 1.18
0.632GlnCys: 0.632 ± 0.526
3.161GlnAsp: 3.161 ± 0.899
3.161GlnGlu: 3.161 ± 1.569
0.632GlnPhe: 0.632 ± 0.487
4.425GlnGly: 4.425 ± 1.596
1.264GlnHis: 1.264 ± 0.839
3.161GlnIle: 3.161 ± 1.927
3.793GlnLys: 3.793 ± 1.804
3.793GlnLeu: 3.793 ± 1.407
1.264GlnMet: 1.264 ± 0.764
1.264GlnAsn: 1.264 ± 0.963
0.0GlnPro: 0.0 ± 0.0
2.528GlnGln: 2.528 ± 1.404
3.793GlnArg: 3.793 ± 1.645
0.632GlnSer: 0.632 ± 0.487
3.793GlnThr: 3.793 ± 1.557
0.632GlnVal: 0.632 ± 0.487
1.264GlnTrp: 1.264 ± 0.963
3.161GlnTyr: 3.161 ± 0.865
0.0GlnXaa: 0.0 ± 0.0
Arg
1.896ArgAla: 1.896 ± 0.588
0.0ArgCys: 0.0 ± 0.0
1.896ArgAsp: 1.896 ± 1.048
3.161ArgGlu: 3.161 ± 1.733
2.528ArgPhe: 2.528 ± 1.359
1.896ArgGly: 1.896 ± 1.289
1.264ArgHis: 1.264 ± 0.455
3.793ArgIle: 3.793 ± 1.268
3.793ArgLys: 3.793 ± 2.018
4.425ArgLeu: 4.425 ± 2.098
1.896ArgMet: 1.896 ± 0.588
5.057ArgAsn: 5.057 ± 1.621
3.161ArgPro: 3.161 ± 1.258
4.425ArgGln: 4.425 ± 1.765
6.321ArgArg: 6.321 ± 3.103
1.264ArgSer: 1.264 ± 0.973
4.425ArgThr: 4.425 ± 2.224
2.528ArgVal: 2.528 ± 1.947
0.0ArgTrp: 0.0 ± 0.0
1.264ArgTyr: 1.264 ± 0.973
0.0ArgXaa: 0.0 ± 0.0
Ser
2.528SerAla: 2.528 ± 0.91
0.0SerCys: 0.0 ± 0.0
1.896SerAsp: 1.896 ± 0.64
3.161SerGlu: 3.161 ± 1.488
2.528SerPhe: 2.528 ± 0.91
3.161SerGly: 3.161 ± 1.686
1.264SerHis: 1.264 ± 0.973
1.264SerIle: 1.264 ± 0.455
6.321SerLys: 6.321 ± 2.556
3.793SerLeu: 3.793 ± 1.425
1.264SerMet: 1.264 ± 0.855
5.057SerAsn: 5.057 ± 1.934
0.632SerPro: 0.632 ± 0.526
0.632SerGln: 0.632 ± 0.487
1.896SerArg: 1.896 ± 0.781
4.425SerSer: 4.425 ± 1.94
2.528SerThr: 2.528 ± 1.359
1.896SerVal: 1.896 ± 1.46
0.0SerTrp: 0.0 ± 0.0
3.161SerTyr: 3.161 ± 1.33
0.0SerXaa: 0.0 ± 0.0
Thr
5.689ThrAla: 5.689 ± 2.075
1.896ThrCys: 1.896 ± 1.581
1.264ThrAsp: 1.264 ± 0.973
4.425ThrGlu: 4.425 ± 1.072
2.528ThrPhe: 2.528 ± 0.91
5.057ThrGly: 5.057 ± 1.934
0.632ThrHis: 0.632 ± 0.526
5.689ThrIle: 5.689 ± 2.223
4.425ThrLys: 4.425 ± 1.64
5.057ThrLeu: 5.057 ± 1.327
1.896ThrMet: 1.896 ± 0.989
8.217ThrAsn: 8.217 ± 1.801
3.161ThrPro: 3.161 ± 1.1
3.793ThrGln: 3.793 ± 1.5
3.793ThrArg: 3.793 ± 1.358
5.057ThrSer: 5.057 ± 0.784
5.057ThrThr: 5.057 ± 3.12
0.632ThrVal: 0.632 ± 0.487
1.896ThrTrp: 1.896 ± 0.64
2.528ThrTyr: 2.528 ± 1.657
0.0ThrXaa: 0.0 ± 0.0
Val
2.528ValAla: 2.528 ± 0.813
0.0ValCys: 0.0 ± 0.0
1.264ValAsp: 1.264 ± 0.764
1.264ValGlu: 1.264 ± 0.973
1.264ValPhe: 1.264 ± 0.455
3.793ValGly: 3.793 ± 2.16
0.632ValHis: 0.632 ± 0.487
3.793ValIle: 3.793 ± 1.557
1.896ValLys: 1.896 ± 0.781
2.528ValLeu: 2.528 ± 1.947
0.0ValMet: 0.0 ± 0.0
1.896ValAsn: 1.896 ± 0.781
1.896ValPro: 1.896 ± 1.048
0.632ValGln: 0.632 ± 0.487
3.793ValArg: 3.793 ± 1.151
1.896ValSer: 1.896 ± 1.46
2.528ValThr: 2.528 ± 1.22
1.264ValVal: 1.264 ± 0.973
2.528ValTrp: 2.528 ± 0.91
0.632ValTyr: 0.632 ± 0.878
0.0ValXaa: 0.0 ± 0.0
Trp
0.632TrpAla: 0.632 ± 0.917
0.0TrpCys: 0.0 ± 0.0
1.264TrpAsp: 1.264 ± 0.855
3.161TrpGlu: 3.161 ± 0.827
0.632TrpPhe: 0.632 ± 0.526
1.264TrpGly: 1.264 ± 1.052
2.528TrpHis: 2.528 ± 0.813
0.632TrpIle: 0.632 ± 0.526
1.896TrpLys: 1.896 ± 1.41
0.632TrpLeu: 0.632 ± 0.526
0.0TrpMet: 0.0 ± 0.0
1.896TrpAsn: 1.896 ± 1.066
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.264TrpArg: 1.264 ± 0.963
0.632TrpSer: 0.632 ± 0.487
2.528TrpThr: 2.528 ± 1.22
0.632TrpVal: 0.632 ± 0.487
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.528TyrAla: 2.528 ± 2.104
0.632TyrCys: 0.632 ± 0.526
0.632TyrAsp: 0.632 ± 0.487
1.896TyrGlu: 1.896 ± 1.227
0.0TyrPhe: 0.0 ± 0.0
1.264TyrGly: 1.264 ± 0.973
1.264TyrHis: 1.264 ± 0.75
1.264TyrIle: 1.264 ± 1.27
2.528TyrLys: 2.528 ± 1.171
2.528TyrLeu: 2.528 ± 0.93
1.264TyrMet: 1.264 ± 0.973
3.161TyrAsn: 3.161 ± 1.246
0.0TyrPro: 0.0 ± 0.0
2.528TyrGln: 2.528 ± 1.359
1.896TyrArg: 1.896 ± 0.714
2.528TyrSer: 2.528 ± 1.404
1.896TyrThr: 1.896 ± 1.075
1.264TyrVal: 1.264 ± 0.921
0.0TyrTrp: 0.0 ± 0.0
0.632TyrTyr: 0.632 ± 0.487
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1583 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski