Amino acid dipepetide frequency for Streptococcus phage Cp-1 (Bacteriophage Cp-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.338AlaAla: 0.338 ± 0.215
0.338AlaCys: 0.338 ± 0.226
4.565AlaAsp: 4.565 ± 0.943
5.241AlaGlu: 5.241 ± 1.322
4.227AlaPhe: 4.227 ± 0.961
3.55AlaGly: 3.55 ± 0.751
0.676AlaHis: 0.676 ± 0.284
3.043AlaIle: 3.043 ± 0.708
4.396AlaLys: 4.396 ± 0.938
8.453AlaLeu: 8.453 ± 1.452
1.352AlaMet: 1.352 ± 0.612
4.565AlaAsn: 4.565 ± 1.284
1.352AlaPro: 1.352 ± 0.42
2.874AlaGln: 2.874 ± 0.747
1.691AlaArg: 1.691 ± 0.491
5.241AlaSer: 5.241 ± 1.232
4.396AlaThr: 4.396 ± 1.051
2.536AlaVal: 2.536 ± 0.775
1.014AlaTrp: 1.014 ± 0.327
2.705AlaTyr: 2.705 ± 0.671
0.0AlaXaa: 0.0 ± 0.0
Cys
0.169CysAla: 0.169 ± 0.165
0.0CysCys: 0.0 ± 0.0
0.676CysAsp: 0.676 ± 0.272
0.169CysGlu: 0.169 ± 0.167
0.676CysPhe: 0.676 ± 0.286
0.0CysGly: 0.0 ± 0.0
0.338CysHis: 0.338 ± 0.195
1.183CysIle: 1.183 ± 0.425
0.507CysLys: 0.507 ± 0.299
1.183CysLeu: 1.183 ± 0.532
0.169CysMet: 0.169 ± 0.162
0.338CysAsn: 0.338 ± 0.262
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.169CysArg: 0.169 ± 0.171
0.507CysSer: 0.507 ± 0.303
0.338CysThr: 0.338 ± 0.22
0.507CysVal: 0.507 ± 0.298
0.169CysTrp: 0.169 ± 0.182
1.183CysTyr: 1.183 ± 0.354
0.0CysXaa: 0.0 ± 0.0
Asp
3.043AspAla: 3.043 ± 0.353
0.338AspCys: 0.338 ± 0.227
3.719AspAsp: 3.719 ± 1.034
4.057AspGlu: 4.057 ± 0.732
4.396AspPhe: 4.396 ± 1.01
4.057AspGly: 4.057 ± 0.65
0.338AspHis: 0.338 ± 0.222
3.719AspIle: 3.719 ± 0.76
6.255AspLys: 6.255 ± 1.042
4.903AspLeu: 4.903 ± 0.903
1.522AspMet: 1.522 ± 0.437
4.227AspAsn: 4.227 ± 0.936
1.352AspPro: 1.352 ± 0.362
1.183AspGln: 1.183 ± 0.458
1.183AspArg: 1.183 ± 0.413
2.705AspSer: 2.705 ± 0.653
3.888AspThr: 3.888 ± 0.931
3.043AspVal: 3.043 ± 0.759
1.014AspTrp: 1.014 ± 0.473
3.888AspTyr: 3.888 ± 0.814
0.0AspXaa: 0.0 ± 0.0
Glu
4.057GluAla: 4.057 ± 0.768
0.507GluCys: 0.507 ± 0.246
3.212GluAsp: 3.212 ± 0.8
6.424GluGlu: 6.424 ± 1.166
4.057GluPhe: 4.057 ± 0.87
2.874GluGly: 2.874 ± 0.666
0.845GluHis: 0.845 ± 0.502
5.241GluIle: 5.241 ± 0.877
5.241GluLys: 5.241 ± 0.865
5.748GluLeu: 5.748 ± 1.342
0.845GluMet: 0.845 ± 0.4
5.41GluAsn: 5.41 ± 0.66
1.183GluPro: 1.183 ± 0.462
2.198GluGln: 2.198 ± 0.491
4.396GluArg: 4.396 ± 1.064
3.719GluSer: 3.719 ± 1.028
4.734GluThr: 4.734 ± 1.008
6.086GluVal: 6.086 ± 1.07
0.676GluTrp: 0.676 ± 0.378
2.198GluTyr: 2.198 ± 0.521
0.0GluXaa: 0.0 ± 0.0
Phe
3.381PheAla: 3.381 ± 0.516
0.845PheCys: 0.845 ± 0.37
3.381PheAsp: 3.381 ± 0.809
3.381PheGlu: 3.381 ± 0.844
2.874PhePhe: 2.874 ± 0.766
2.367PheGly: 2.367 ± 0.603
0.845PheHis: 0.845 ± 0.394
4.057PheIle: 4.057 ± 1.047
5.579PheLys: 5.579 ± 0.724
3.888PheLeu: 3.888 ± 0.861
1.352PheMet: 1.352 ± 0.536
3.043PheAsn: 3.043 ± 0.954
1.691PhePro: 1.691 ± 0.685
2.705PheGln: 2.705 ± 0.494
2.705PheArg: 2.705 ± 0.606
3.212PheSer: 3.212 ± 0.801
3.55PheThr: 3.55 ± 0.841
3.888PheVal: 3.888 ± 0.677
1.014PheTrp: 1.014 ± 0.494
2.705PheTyr: 2.705 ± 0.824
0.0PheXaa: 0.0 ± 0.0
Gly
2.705GlyAla: 2.705 ± 0.615
0.507GlyCys: 0.507 ± 0.32
3.55GlyAsp: 3.55 ± 0.896
2.198GlyGlu: 2.198 ± 0.408
2.198GlyPhe: 2.198 ± 0.547
3.212GlyGly: 3.212 ± 1.158
0.676GlyHis: 0.676 ± 0.32
3.55GlyIle: 3.55 ± 0.847
3.888GlyLys: 3.888 ± 0.792
3.888GlyLeu: 3.888 ± 0.916
1.352GlyMet: 1.352 ± 0.459
3.55GlyAsn: 3.55 ± 1.179
0.169GlyPro: 0.169 ± 0.174
3.212GlyGln: 3.212 ± 1.176
3.381GlyArg: 3.381 ± 0.708
3.212GlySer: 3.212 ± 1.145
2.536GlyThr: 2.536 ± 0.64
3.888GlyVal: 3.888 ± 0.693
1.183GlyTrp: 1.183 ± 0.676
3.55GlyTyr: 3.55 ± 0.902
0.0GlyXaa: 0.0 ± 0.0
His
0.845HisAla: 0.845 ± 0.416
0.0HisCys: 0.0 ± 0.0
0.507HisAsp: 0.507 ± 0.359
0.845HisGlu: 0.845 ± 0.338
1.014HisPhe: 1.014 ± 0.34
0.338HisGly: 0.338 ± 0.253
0.338HisHis: 0.338 ± 0.334
1.183HisIle: 1.183 ± 0.466
1.014HisLys: 1.014 ± 0.349
1.014HisLeu: 1.014 ± 0.435
0.676HisMet: 0.676 ± 0.292
0.676HisAsn: 0.676 ± 0.292
0.169HisPro: 0.169 ± 0.167
0.507HisGln: 0.507 ± 0.269
0.169HisArg: 0.169 ± 0.171
1.014HisSer: 1.014 ± 0.399
0.845HisThr: 0.845 ± 0.372
1.352HisVal: 1.352 ± 0.346
0.338HisTrp: 0.338 ± 0.269
1.522HisTyr: 1.522 ± 0.457
0.0HisXaa: 0.0 ± 0.0
Ile
4.396IleAla: 4.396 ± 0.725
0.338IleCys: 0.338 ± 0.22
5.072IleAsp: 5.072 ± 0.844
5.579IleGlu: 5.579 ± 1.133
4.057IlePhe: 4.057 ± 0.634
4.227IleGly: 4.227 ± 1.06
1.183IleHis: 1.183 ± 0.533
4.057IleIle: 4.057 ± 0.69
5.579IleLys: 5.579 ± 0.788
6.255IleLeu: 6.255 ± 1.319
1.86IleMet: 1.86 ± 0.605
4.396IleAsn: 4.396 ± 0.817
3.043IlePro: 3.043 ± 0.623
3.212IleGln: 3.212 ± 0.758
2.536IleArg: 2.536 ± 0.69
4.227IleSer: 4.227 ± 1.069
4.227IleThr: 4.227 ± 0.717
3.381IleVal: 3.381 ± 0.675
0.507IleTrp: 0.507 ± 0.316
2.536IleTyr: 2.536 ± 0.605
0.0IleXaa: 0.0 ± 0.0
Lys
5.748LysAla: 5.748 ± 1.22
0.338LysCys: 0.338 ± 0.195
3.381LysAsp: 3.381 ± 0.722
5.41LysGlu: 5.41 ± 1.041
3.55LysPhe: 3.55 ± 0.934
4.057LysGly: 4.057 ± 1.068
1.691LysHis: 1.691 ± 0.711
6.255LysIle: 6.255 ± 0.96
5.917LysLys: 5.917 ± 1.041
5.917LysLeu: 5.917 ± 1.484
2.536LysMet: 2.536 ± 0.455
5.579LysAsn: 5.579 ± 1.07
2.705LysPro: 2.705 ± 0.702
4.227LysGln: 4.227 ± 0.922
3.381LysArg: 3.381 ± 0.832
6.932LysSer: 6.932 ± 1.255
3.212LysThr: 3.212 ± 0.676
3.043LysVal: 3.043 ± 0.84
1.183LysTrp: 1.183 ± 0.443
3.043LysTyr: 3.043 ± 0.71
0.0LysXaa: 0.0 ± 0.0
Leu
4.734LeuAla: 4.734 ± 0.929
0.507LeuCys: 0.507 ± 0.383
5.917LeuAsp: 5.917 ± 1.364
6.762LeuGlu: 6.762 ± 1.176
4.396LeuPhe: 4.396 ± 0.901
2.198LeuGly: 2.198 ± 0.896
1.014LeuHis: 1.014 ± 0.415
4.396LeuIle: 4.396 ± 0.855
9.637LeuLys: 9.637 ± 1.826
5.579LeuLeu: 5.579 ± 0.916
0.845LeuMet: 0.845 ± 0.385
7.101LeuAsn: 7.101 ± 0.807
1.86LeuPro: 1.86 ± 0.838
2.029LeuGln: 2.029 ± 0.574
4.057LeuArg: 4.057 ± 0.983
5.579LeuSer: 5.579 ± 0.925
6.086LeuThr: 6.086 ± 1.055
5.41LeuVal: 5.41 ± 0.783
1.014LeuTrp: 1.014 ± 0.422
4.734LeuTyr: 4.734 ± 0.932
0.0LeuXaa: 0.0 ± 0.0
Met
2.029MetAla: 2.029 ± 0.548
0.169MetCys: 0.169 ± 0.163
0.507MetAsp: 0.507 ± 0.372
2.029MetGlu: 2.029 ± 0.507
0.845MetPhe: 0.845 ± 0.37
1.183MetGly: 1.183 ± 0.427
0.169MetHis: 0.169 ± 0.162
1.691MetIle: 1.691 ± 0.526
1.86MetLys: 1.86 ± 0.644
2.536MetLeu: 2.536 ± 0.788
0.169MetMet: 0.169 ± 0.179
1.86MetAsn: 1.86 ± 0.592
0.338MetPro: 0.338 ± 0.214
0.845MetGln: 0.845 ± 0.441
0.676MetArg: 0.676 ± 0.282
1.522MetSer: 1.522 ± 0.482
2.367MetThr: 2.367 ± 0.712
1.014MetVal: 1.014 ± 0.503
0.0MetTrp: 0.0 ± 0.0
1.014MetTyr: 1.014 ± 0.515
0.0MetXaa: 0.0 ± 0.0
Asn
5.748AsnAla: 5.748 ± 0.893
0.0AsnCys: 0.0 ± 0.0
4.903AsnAsp: 4.903 ± 0.661
4.565AsnGlu: 4.565 ± 0.826
4.565AsnPhe: 4.565 ± 0.851
4.903AsnGly: 4.903 ± 0.917
1.352AsnHis: 1.352 ± 0.489
4.057AsnIle: 4.057 ± 0.877
4.396AsnLys: 4.396 ± 0.914
4.903AsnLeu: 4.903 ± 0.846
2.029AsnMet: 2.029 ± 0.75
5.241AsnAsn: 5.241 ± 0.963
3.381AsnPro: 3.381 ± 0.905
2.705AsnGln: 2.705 ± 0.776
2.367AsnArg: 2.367 ± 0.514
2.874AsnSer: 2.874 ± 0.569
3.719AsnThr: 3.719 ± 0.686
3.55AsnVal: 3.55 ± 0.727
0.507AsnTrp: 0.507 ± 0.268
2.874AsnTyr: 2.874 ± 0.738
0.0AsnXaa: 0.0 ± 0.0
Pro
1.86ProAla: 1.86 ± 0.526
0.507ProCys: 0.507 ± 0.271
1.691ProAsp: 1.691 ± 0.533
1.522ProGlu: 1.522 ± 0.514
1.86ProPhe: 1.86 ± 0.54
0.0ProGly: 0.0 ± 0.0
0.507ProHis: 0.507 ± 0.295
1.522ProIle: 1.522 ± 0.636
1.522ProLys: 1.522 ± 0.499
2.367ProLeu: 2.367 ± 0.679
0.338ProMet: 0.338 ± 0.266
2.705ProAsn: 2.705 ± 0.751
0.845ProPro: 0.845 ± 0.481
0.676ProGln: 0.676 ± 0.289
0.676ProArg: 0.676 ± 0.294
2.536ProSer: 2.536 ± 0.652
1.522ProThr: 1.522 ± 0.508
2.874ProVal: 2.874 ± 0.888
0.507ProTrp: 0.507 ± 0.322
1.352ProTyr: 1.352 ± 0.482
0.0ProXaa: 0.0 ± 0.0
Gln
3.55GlnAla: 3.55 ± 0.768
0.169GlnCys: 0.169 ± 0.207
2.367GlnAsp: 2.367 ± 0.852
2.536GlnGlu: 2.536 ± 0.529
1.86GlnPhe: 1.86 ± 0.507
1.691GlnGly: 1.691 ± 0.488
0.169GlnHis: 0.169 ± 0.171
2.705GlnIle: 2.705 ± 0.612
2.874GlnLys: 2.874 ± 0.544
2.874GlnLeu: 2.874 ± 0.73
1.014GlnMet: 1.014 ± 0.41
1.352GlnAsn: 1.352 ± 0.518
1.86GlnPro: 1.86 ± 0.513
2.874GlnGln: 2.874 ± 0.79
1.522GlnArg: 1.522 ± 0.53
2.536GlnSer: 2.536 ± 1.028
1.691GlnThr: 1.691 ± 0.468
2.198GlnVal: 2.198 ± 0.486
0.507GlnTrp: 0.507 ± 0.265
1.691GlnTyr: 1.691 ± 0.487
0.0GlnXaa: 0.0 ± 0.0
Arg
2.705ArgAla: 2.705 ± 0.573
0.338ArgCys: 0.338 ± 0.233
2.029ArgAsp: 2.029 ± 0.698
1.183ArgGlu: 1.183 ± 0.432
3.212ArgPhe: 3.212 ± 0.563
2.705ArgGly: 2.705 ± 0.607
0.338ArgHis: 0.338 ± 0.228
3.212ArgIle: 3.212 ± 0.698
3.55ArgLys: 3.55 ± 0.806
3.381ArgLeu: 3.381 ± 0.606
0.338ArgMet: 0.338 ± 0.272
2.705ArgAsn: 2.705 ± 0.839
1.352ArgPro: 1.352 ± 0.42
0.845ArgGln: 0.845 ± 0.361
2.536ArgArg: 2.536 ± 0.88
1.86ArgSer: 1.86 ± 0.703
2.705ArgThr: 2.705 ± 0.585
2.536ArgVal: 2.536 ± 0.847
0.507ArgTrp: 0.507 ± 0.276
1.691ArgTyr: 1.691 ± 0.525
0.0ArgXaa: 0.0 ± 0.0
Ser
4.227SerAla: 4.227 ± 0.699
0.676SerCys: 0.676 ± 0.3
3.719SerAsp: 3.719 ± 0.752
3.888SerGlu: 3.888 ± 0.508
2.029SerPhe: 2.029 ± 0.625
4.903SerGly: 4.903 ± 1.449
1.183SerHis: 1.183 ± 0.557
4.396SerIle: 4.396 ± 0.611
3.888SerLys: 3.888 ± 0.783
5.241SerLeu: 5.241 ± 0.959
2.367SerMet: 2.367 ± 0.601
4.565SerAsn: 4.565 ± 0.754
1.522SerPro: 1.522 ± 0.538
2.536SerGln: 2.536 ± 0.773
2.536SerArg: 2.536 ± 0.856
4.057SerSer: 4.057 ± 0.967
4.057SerThr: 4.057 ± 1.061
4.396SerVal: 4.396 ± 0.886
0.845SerTrp: 0.845 ± 0.334
3.212SerTyr: 3.212 ± 0.835
0.0SerXaa: 0.0 ± 0.0
Thr
4.227ThrAla: 4.227 ± 0.992
0.676ThrCys: 0.676 ± 0.3
2.198ThrAsp: 2.198 ± 0.585
4.227ThrGlu: 4.227 ± 0.935
4.227ThrPhe: 4.227 ± 0.884
4.565ThrGly: 4.565 ± 1.002
0.676ThrHis: 0.676 ± 0.314
4.734ThrIle: 4.734 ± 0.85
3.719ThrLys: 3.719 ± 1.008
6.086ThrLeu: 6.086 ± 1.171
0.676ThrMet: 0.676 ± 0.384
3.381ThrAsn: 3.381 ± 0.798
2.705ThrPro: 2.705 ± 0.764
1.352ThrGln: 1.352 ± 0.529
1.86ThrArg: 1.86 ± 0.65
4.057ThrSer: 4.057 ± 0.701
4.734ThrThr: 4.734 ± 1.058
3.212ThrVal: 3.212 ± 0.86
0.507ThrTrp: 0.507 ± 0.242
3.043ThrTyr: 3.043 ± 0.762
0.0ThrXaa: 0.0 ± 0.0
Val
5.072ValAla: 5.072 ± 0.816
1.183ValCys: 1.183 ± 0.425
3.719ValAsp: 3.719 ± 0.595
4.734ValGlu: 4.734 ± 0.792
2.536ValPhe: 2.536 ± 0.751
2.874ValGly: 2.874 ± 0.621
1.183ValHis: 1.183 ± 0.412
5.748ValIle: 5.748 ± 0.791
4.227ValLys: 4.227 ± 0.916
2.705ValLeu: 2.705 ± 0.705
1.86ValMet: 1.86 ± 0.498
3.719ValAsn: 3.719 ± 0.852
1.352ValPro: 1.352 ± 0.449
1.691ValGln: 1.691 ± 0.613
1.86ValArg: 1.86 ± 0.483
4.396ValSer: 4.396 ± 0.706
3.212ValThr: 3.212 ± 0.645
3.212ValVal: 3.212 ± 0.826
1.014ValTrp: 1.014 ± 0.468
2.536ValTyr: 2.536 ± 0.522
0.0ValXaa: 0.0 ± 0.0
Trp
1.014TrpAla: 1.014 ± 0.392
0.0TrpCys: 0.0 ± 0.0
0.507TrpAsp: 0.507 ± 0.316
0.676TrpGlu: 0.676 ± 0.288
1.183TrpPhe: 1.183 ± 0.492
0.676TrpGly: 0.676 ± 0.302
0.0TrpHis: 0.0 ± 0.0
1.352TrpIle: 1.352 ± 0.384
1.014TrpLys: 1.014 ± 0.494
1.352TrpLeu: 1.352 ± 0.499
0.0TrpMet: 0.0 ± 0.0
0.676TrpAsn: 0.676 ± 0.347
0.0TrpPro: 0.0 ± 0.0
0.507TrpGln: 0.507 ± 0.316
0.0TrpArg: 0.0 ± 0.0
0.676TrpSer: 0.676 ± 0.335
1.014TrpThr: 1.014 ± 0.466
0.676TrpVal: 0.676 ± 0.346
0.676TrpTrp: 0.676 ± 0.363
1.691TrpTyr: 1.691 ± 0.807
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.705TyrAla: 2.705 ± 0.86
0.845TyrCys: 0.845 ± 0.4
3.212TyrAsp: 3.212 ± 0.707
4.227TyrGlu: 4.227 ± 0.849
2.705TyrPhe: 2.705 ± 0.91
2.029TyrGly: 2.029 ± 0.508
0.845TyrHis: 0.845 ± 0.369
4.565TyrIle: 4.565 ± 0.713
3.043TyrLys: 3.043 ± 0.761
5.579TyrLeu: 5.579 ± 1.349
1.352TyrMet: 1.352 ± 0.437
3.55TyrAsn: 3.55 ± 0.732
0.507TyrPro: 0.507 ± 0.222
1.86TyrGln: 1.86 ± 0.596
2.198TyrArg: 2.198 ± 0.605
3.381TyrSer: 3.381 ± 0.685
2.029TyrThr: 2.029 ± 0.472
2.029TyrVal: 2.029 ± 0.667
0.507TyrTrp: 0.507 ± 0.271
3.381TyrTyr: 3.381 ± 1.042
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 28 proteins (5916 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski