Amino acid dipepetide frequency for Chitinophaga barathri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.618AlaAla: 8.618 ± 0.101
0.808AlaCys: 0.808 ± 0.022
4.533AlaAsp: 4.533 ± 0.057
4.593AlaGlu: 4.593 ± 0.053
3.627AlaPhe: 3.627 ± 0.05
7.279AlaGly: 7.279 ± 0.086
1.295AlaHis: 1.295 ± 0.028
4.895AlaIle: 4.895 ± 0.056
4.041AlaLys: 4.041 ± 0.047
7.478AlaLeu: 7.478 ± 0.074
2.022AlaMet: 2.022 ± 0.035
3.532AlaAsn: 3.532 ± 0.059
3.294AlaPro: 3.294 ± 0.065
3.105AlaGln: 3.105 ± 0.041
3.607AlaArg: 3.607 ± 0.045
4.77AlaSer: 4.77 ± 0.06
4.724AlaThr: 4.724 ± 0.116
5.678AlaVal: 5.678 ± 0.055
1.051AlaTrp: 1.051 ± 0.025
3.086AlaTyr: 3.086 ± 0.039
0.0AlaXaa: 0.0 ± 0.0
Cys
0.554CysAla: 0.554 ± 0.016
0.137CysCys: 0.137 ± 0.009
0.39CysAsp: 0.39 ± 0.025
0.367CysGlu: 0.367 ± 0.016
0.411CysPhe: 0.411 ± 0.015
0.683CysGly: 0.683 ± 0.024
0.177CysHis: 0.177 ± 0.01
0.566CysIle: 0.566 ± 0.019
0.433CysLys: 0.433 ± 0.015
0.812CysLeu: 0.812 ± 0.024
0.226CysMet: 0.226 ± 0.011
0.403CysAsn: 0.403 ± 0.026
0.326CysPro: 0.326 ± 0.014
0.222CysGln: 0.222 ± 0.01
0.411CysArg: 0.411 ± 0.017
0.498CysSer: 0.498 ± 0.019
0.493CysThr: 0.493 ± 0.028
0.469CysVal: 0.469 ± 0.016
0.112CysTrp: 0.112 ± 0.008
0.325CysTyr: 0.325 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
4.332AspAla: 4.332 ± 0.056
0.347AspCys: 0.347 ± 0.016
2.327AspAsp: 2.327 ± 0.041
3.049AspGlu: 3.049 ± 0.047
2.669AspPhe: 2.669 ± 0.041
4.067AspGly: 4.067 ± 0.061
1.042AspHis: 1.042 ± 0.023
3.651AspIle: 3.651 ± 0.042
3.282AspLys: 3.282 ± 0.048
4.559AspLeu: 4.559 ± 0.052
1.277AspMet: 1.277 ± 0.024
2.561AspAsn: 2.561 ± 0.042
2.454AspPro: 2.454 ± 0.039
1.749AspGln: 1.749 ± 0.031
2.389AspArg: 2.389 ± 0.032
2.78AspSer: 2.78 ± 0.051
2.776AspThr: 2.776 ± 0.056
3.493AspVal: 3.493 ± 0.047
0.816AspTrp: 0.816 ± 0.021
2.373AspTyr: 2.373 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
4.498GluAla: 4.498 ± 0.062
0.344GluCys: 0.344 ± 0.02
2.781GluAsp: 2.781 ± 0.047
3.775GluGlu: 3.775 ± 0.067
2.227GluPhe: 2.227 ± 0.033
3.794GluGly: 3.794 ± 0.052
1.104GluHis: 1.104 ± 0.029
3.638GluIle: 3.638 ± 0.048
4.501GluLys: 4.501 ± 0.061
5.45GluLeu: 5.45 ± 0.072
1.534GluMet: 1.534 ± 0.027
2.964GluAsn: 2.964 ± 0.038
1.881GluPro: 1.881 ± 0.037
2.475GluGln: 2.475 ± 0.044
2.76GluArg: 2.76 ± 0.043
2.564GluSer: 2.564 ± 0.034
3.115GluThr: 3.115 ± 0.047
3.678GluVal: 3.678 ± 0.051
0.763GluTrp: 0.763 ± 0.02
2.061GluTyr: 2.061 ± 0.034
0.0GluXaa: 0.0 ± 0.0
Phe
3.299PheAla: 3.299 ± 0.043
0.428PheCys: 0.428 ± 0.015
2.56PheAsp: 2.56 ± 0.036
2.479PheGlu: 2.479 ± 0.04
2.297PhePhe: 2.297 ± 0.042
3.346PheGly: 3.346 ± 0.045
0.885PheHis: 0.885 ± 0.02
2.915PheIle: 2.915 ± 0.044
2.364PheLys: 2.364 ± 0.041
4.16PheLeu: 4.16 ± 0.056
1.166PheMet: 1.166 ± 0.027
2.615PheAsn: 2.615 ± 0.035
1.931PhePro: 1.931 ± 0.03
1.441PheGln: 1.441 ± 0.027
2.534PheArg: 2.534 ± 0.038
3.692PheSer: 3.692 ± 0.044
3.359PheThr: 3.359 ± 0.051
2.716PheVal: 2.716 ± 0.043
0.596PheTrp: 0.596 ± 0.019
1.961PheTyr: 1.961 ± 0.034
0.0PheXaa: 0.0 ± 0.0
Gly
5.635GlyAla: 5.635 ± 0.072
0.69GlyCys: 0.69 ± 0.035
3.576GlyAsp: 3.576 ± 0.047
3.776GlyGlu: 3.776 ± 0.047
3.686GlyPhe: 3.686 ± 0.048
5.886GlyGly: 5.886 ± 0.086
1.34GlyHis: 1.34 ± 0.027
5.242GlyIle: 5.242 ± 0.055
5.253GlyLys: 5.253 ± 0.059
6.499GlyLeu: 6.499 ± 0.065
1.985GlyMet: 1.985 ± 0.033
4.116GlyAsn: 4.116 ± 0.063
2.046GlyPro: 2.046 ± 0.033
2.589GlyGln: 2.589 ± 0.04
3.455GlyArg: 3.455 ± 0.041
4.714GlySer: 4.714 ± 0.062
4.87GlyThr: 4.87 ± 0.115
4.797GlyVal: 4.797 ± 0.056
1.153GlyTrp: 1.153 ± 0.027
3.289GlyTyr: 3.289 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
1.375HisAla: 1.375 ± 0.029
0.208HisCys: 0.208 ± 0.011
0.824HisAsp: 0.824 ± 0.021
1.011HisGlu: 1.011 ± 0.029
1.144HisPhe: 1.144 ± 0.028
1.237HisGly: 1.237 ± 0.025
0.584HisHis: 0.584 ± 0.017
1.319HisIle: 1.319 ± 0.025
0.897HisLys: 0.897 ± 0.026
1.928HisLeu: 1.928 ± 0.035
0.434HisMet: 0.434 ± 0.016
0.956HisAsn: 0.956 ± 0.025
1.148HisPro: 1.148 ± 0.026
0.73HisGln: 0.73 ± 0.021
0.956HisArg: 0.956 ± 0.026
1.047HisSer: 1.047 ± 0.023
1.216HisThr: 1.216 ± 0.027
1.046HisVal: 1.046 ± 0.025
0.285HisTrp: 0.285 ± 0.013
0.878HisTyr: 0.878 ± 0.023
0.0HisXaa: 0.0 ± 0.0
Ile
5.219IleAla: 5.219 ± 0.057
0.637IleCys: 0.637 ± 0.02
3.246IleAsp: 3.246 ± 0.047
3.133IleGlu: 3.133 ± 0.045
2.768IlePhe: 2.768 ± 0.046
4.417IleGly: 4.417 ± 0.054
1.263IleHis: 1.263 ± 0.03
3.769IleIle: 3.769 ± 0.054
3.301IleLys: 3.301 ± 0.044
5.554IleLeu: 5.554 ± 0.057
1.306IleMet: 1.306 ± 0.029
3.077IleAsn: 3.077 ± 0.042
3.193IlePro: 3.193 ± 0.044
2.149IleGln: 2.149 ± 0.033
3.742IleArg: 3.742 ± 0.044
4.463IleSer: 4.463 ± 0.051
4.65IleThr: 4.65 ± 0.095
3.803IleVal: 3.803 ± 0.047
0.724IleTrp: 0.724 ± 0.021
2.336IleTyr: 2.336 ± 0.035
0.0IleXaa: 0.0 ± 0.0
Lys
4.721LysAla: 4.721 ± 0.064
0.279LysCys: 0.279 ± 0.011
3.771LysAsp: 3.771 ± 0.047
4.198LysGlu: 4.198 ± 0.065
2.036LysPhe: 2.036 ± 0.034
4.414LysGly: 4.414 ± 0.055
1.106LysHis: 1.106 ± 0.026
3.573LysIle: 3.573 ± 0.052
4.3LysLys: 4.3 ± 0.065
5.028LysLeu: 5.028 ± 0.06
1.761LysMet: 1.761 ± 0.033
2.992LysAsn: 2.992 ± 0.044
2.673LysPro: 2.673 ± 0.043
2.385LysGln: 2.385 ± 0.034
2.587LysArg: 2.587 ± 0.043
2.881LysSer: 2.881 ± 0.041
3.615LysThr: 3.615 ± 0.043
4.028LysVal: 4.028 ± 0.052
0.791LysTrp: 0.791 ± 0.02
2.343LysTyr: 2.343 ± 0.036
0.0LysXaa: 0.0 ± 0.0
Leu
7.395LeuAla: 7.395 ± 0.072
0.855LeuCys: 0.855 ± 0.021
4.732LeuAsp: 4.732 ± 0.049
5.288LeuGlu: 5.288 ± 0.064
4.352LeuPhe: 4.352 ± 0.055
6.017LeuGly: 6.017 ± 0.07
1.954LeuHis: 1.954 ± 0.035
5.173LeuIle: 5.173 ± 0.064
5.888LeuLys: 5.888 ± 0.06
9.643LeuLeu: 9.643 ± 0.099
2.266LeuMet: 2.266 ± 0.037
4.598LeuAsn: 4.598 ± 0.056
4.668LeuPro: 4.668 ± 0.052
4.246LeuGln: 4.246 ± 0.051
4.819LeuArg: 4.819 ± 0.056
6.336LeuSer: 6.336 ± 0.057
5.461LeuThr: 5.461 ± 0.067
5.522LeuVal: 5.522 ± 0.057
1.012LeuTrp: 1.012 ± 0.027
3.367LeuTyr: 3.367 ± 0.049
0.0LeuXaa: 0.0 ± 0.0
Met
2.084MetAla: 2.084 ± 0.033
0.13MetCys: 0.13 ± 0.008
1.339MetAsp: 1.339 ± 0.026
1.59MetGlu: 1.59 ± 0.031
0.876MetPhe: 0.876 ± 0.022
1.613MetGly: 1.613 ± 0.029
0.489MetHis: 0.489 ± 0.017
1.505MetIle: 1.505 ± 0.026
1.989MetLys: 1.989 ± 0.038
2.387MetLeu: 2.387 ± 0.036
0.638MetMet: 0.638 ± 0.019
1.272MetAsn: 1.272 ± 0.026
1.284MetPro: 1.284 ± 0.027
1.209MetGln: 1.209 ± 0.026
1.217MetArg: 1.217 ± 0.024
1.292MetSer: 1.292 ± 0.027
1.235MetThr: 1.235 ± 0.022
1.477MetVal: 1.477 ± 0.026
0.218MetTrp: 0.218 ± 0.011
0.764MetTyr: 0.764 ± 0.019
0.0MetXaa: 0.0 ± 0.0
Asn
3.929AsnAla: 3.929 ± 0.05
0.366AsnCys: 0.366 ± 0.021
2.517AsnAsp: 2.517 ± 0.051
2.459AsnGlu: 2.459 ± 0.039
2.269AsnPhe: 2.269 ± 0.044
4.356AsnGly: 4.356 ± 0.086
0.832AsnHis: 0.832 ± 0.02
3.64AsnIle: 3.64 ± 0.05
2.813AsnLys: 2.813 ± 0.041
4.318AsnLeu: 4.318 ± 0.055
1.152AsnMet: 1.152 ± 0.025
2.763AsnAsn: 2.763 ± 0.052
2.637AsnPro: 2.637 ± 0.038
1.581AsnGln: 1.581 ± 0.029
2.485AsnArg: 2.485 ± 0.038
2.854AsnSer: 2.854 ± 0.051
3.218AsnThr: 3.218 ± 0.052
3.199AsnVal: 3.199 ± 0.052
0.707AsnTrp: 0.707 ± 0.019
2.257AsnTyr: 2.257 ± 0.042
0.0AsnXaa: 0.0 ± 0.0
Pro
4.669ProAla: 4.669 ± 0.077
0.245ProCys: 0.245 ± 0.011
2.943ProAsp: 2.943 ± 0.037
3.137ProGlu: 3.137 ± 0.048
2.018ProPhe: 2.018 ± 0.038
4.032ProGly: 4.032 ± 0.052
0.778ProHis: 0.778 ± 0.02
1.972ProIle: 1.972 ± 0.029
1.96ProLys: 1.96 ± 0.035
3.853ProLeu: 3.853 ± 0.043
0.922ProMet: 0.922 ± 0.02
1.809ProAsn: 1.809 ± 0.032
1.599ProPro: 1.599 ± 0.041
1.625ProGln: 1.625 ± 0.032
1.67ProArg: 1.67 ± 0.029
2.493ProSer: 2.493 ± 0.034
1.995ProThr: 1.995 ± 0.034
3.985ProVal: 3.985 ± 0.059
0.533ProTrp: 0.533 ± 0.02
1.696ProTyr: 1.696 ± 0.041
0.0ProXaa: 0.0 ± 0.0
Gln
3.03GlnAla: 3.03 ± 0.046
0.243GlnCys: 0.243 ± 0.011
1.801GlnAsp: 1.801 ± 0.033
2.22GlnGlu: 2.22 ± 0.039
1.705GlnPhe: 1.705 ± 0.036
2.318GlnGly: 2.318 ± 0.031
0.966GlnHis: 0.966 ± 0.023
1.968GlnIle: 1.968 ± 0.035
2.199GlnLys: 2.199 ± 0.039
4.195GlnLeu: 4.195 ± 0.056
0.987GlnMet: 0.987 ± 0.023
1.763GlnAsn: 1.763 ± 0.027
2.006GlnPro: 2.006 ± 0.035
2.438GlnGln: 2.438 ± 0.039
1.855GlnArg: 1.855 ± 0.03
2.011GlnSer: 2.011 ± 0.032
2.058GlnThr: 2.058 ± 0.033
2.614GlnVal: 2.614 ± 0.042
0.557GlnTrp: 0.557 ± 0.017
1.722GlnTyr: 1.722 ± 0.03
0.0GlnXaa: 0.0 ± 0.0
Arg
3.146ArgAla: 3.146 ± 0.043
0.293ArgCys: 0.293 ± 0.012
2.322ArgAsp: 2.322 ± 0.04
3.008ArgGlu: 3.008 ± 0.052
2.557ArgPhe: 2.557 ± 0.037
2.739ArgGly: 2.739 ± 0.038
1.043ArgHis: 1.043 ± 0.024
3.531ArgIle: 3.531 ± 0.046
3.24ArgLys: 3.24 ± 0.051
4.773ArgLeu: 4.773 ± 0.053
1.364ArgMet: 1.364 ± 0.027
2.761ArgAsn: 2.761 ± 0.041
1.878ArgPro: 1.878 ± 0.033
2.229ArgGln: 2.229 ± 0.036
2.374ArgArg: 2.374 ± 0.041
2.656ArgSer: 2.656 ± 0.034
2.572ArgThr: 2.572 ± 0.031
2.923ArgVal: 2.923 ± 0.036
0.781ArgTrp: 0.781 ± 0.022
2.261ArgTyr: 2.261 ± 0.035
0.0ArgXaa: 0.0 ± 0.0
Ser
5.034SerAla: 5.034 ± 0.051
0.554SerCys: 0.554 ± 0.017
2.703SerAsp: 2.703 ± 0.039
2.688SerGlu: 2.688 ± 0.039
3.303SerPhe: 3.303 ± 0.044
5.228SerGly: 5.228 ± 0.06
1.048SerHis: 1.048 ± 0.023
3.956SerIle: 3.956 ± 0.049
2.849SerLys: 2.849 ± 0.041
6.055SerLeu: 6.055 ± 0.06
1.394SerMet: 1.394 ± 0.026
2.729SerAsn: 2.729 ± 0.047
2.617SerPro: 2.617 ± 0.041
1.938SerGln: 1.938 ± 0.032
3.019SerArg: 3.019 ± 0.043
3.661SerSer: 3.661 ± 0.057
3.397SerThr: 3.397 ± 0.058
4.139SerVal: 4.139 ± 0.057
0.92SerTrp: 0.92 ± 0.023
2.519SerTyr: 2.519 ± 0.043
0.0SerXaa: 0.0 ± 0.0
Thr
5.724ThrAla: 5.724 ± 0.138
0.4ThrCys: 0.4 ± 0.021
3.481ThrAsp: 3.481 ± 0.058
2.929ThrGlu: 2.929 ± 0.043
2.823ThrPhe: 2.823 ± 0.042
5.796ThrGly: 5.796 ± 0.086
0.996ThrHis: 0.996 ± 0.023
3.873ThrIle: 3.873 ± 0.064
2.668ThrLys: 2.668 ± 0.042
5.623ThrLeu: 5.623 ± 0.068
1.149ThrMet: 1.149 ± 0.026
2.557ThrAsn: 2.557 ± 0.051
3.097ThrPro: 3.097 ± 0.057
1.914ThrGln: 1.914 ± 0.032
2.574ThrArg: 2.574 ± 0.036
3.365ThrSer: 3.365 ± 0.055
3.535ThrThr: 3.535 ± 0.077
4.721ThrVal: 4.721 ± 0.113
0.825ThrTrp: 0.825 ± 0.023
2.355ThrTyr: 2.355 ± 0.056
0.0ThrXaa: 0.0 ± 0.0
Val
4.891ValAla: 4.891 ± 0.06
0.588ValCys: 0.588 ± 0.019
3.14ValAsp: 3.14 ± 0.041
3.38ValGlu: 3.38 ± 0.049
3.206ValPhe: 3.206 ± 0.041
3.572ValGly: 3.572 ± 0.045
1.173ValHis: 1.173 ± 0.028
4.528ValIle: 4.528 ± 0.057
4.295ValLys: 4.295 ± 0.055
6.191ValLeu: 6.191 ± 0.06
1.75ValMet: 1.75 ± 0.032
3.726ValAsn: 3.726 ± 0.062
2.984ValPro: 2.984 ± 0.044
2.41ValGln: 2.41 ± 0.036
3.017ValArg: 3.017 ± 0.033
4.365ValSer: 4.365 ± 0.055
4.641ValThr: 4.641 ± 0.097
4.213ValVal: 4.213 ± 0.052
0.807ValTrp: 0.807 ± 0.019
2.573ValTyr: 2.573 ± 0.034
0.0ValXaa: 0.0 ± 0.0
Trp
0.908TrpAla: 0.908 ± 0.026
0.113TrpCys: 0.113 ± 0.007
0.725TrpAsp: 0.725 ± 0.02
0.806TrpGlu: 0.806 ± 0.02
0.584TrpPhe: 0.584 ± 0.016
0.96TrpGly: 0.96 ± 0.022
0.294TrpHis: 0.294 ± 0.013
0.737TrpIle: 0.737 ± 0.022
0.935TrpLys: 0.935 ± 0.022
1.37TrpLeu: 1.37 ± 0.031
0.428TrpMet: 0.428 ± 0.014
0.767TrpAsn: 0.767 ± 0.021
0.442TrpPro: 0.442 ± 0.015
0.665TrpGln: 0.665 ± 0.019
0.66TrpArg: 0.66 ± 0.019
0.724TrpSer: 0.724 ± 0.022
0.734TrpThr: 0.734 ± 0.019
0.775TrpVal: 0.775 ± 0.02
0.27TrpTrp: 0.27 ± 0.013
0.575TrpTyr: 0.575 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.975TyrAla: 2.975 ± 0.042
0.349TyrCys: 0.349 ± 0.013
2.282TyrAsp: 2.282 ± 0.037
2.021TyrGlu: 2.021 ± 0.035
2.185TyrPhe: 2.185 ± 0.037
2.843TyrGly: 2.843 ± 0.042
0.853TyrHis: 0.853 ± 0.023
2.3TyrIle: 2.3 ± 0.034
2.277TyrLys: 2.277 ± 0.035
3.717TyrLeu: 3.717 ± 0.049
0.847TyrMet: 0.847 ± 0.023
2.391TyrAsn: 2.391 ± 0.043
1.775TyrPro: 1.775 ± 0.034
1.559TyrGln: 1.559 ± 0.03
2.319TyrArg: 2.319 ± 0.038
2.583TyrSer: 2.583 ± 0.043
2.741TyrThr: 2.741 ± 0.059
2.175TyrVal: 2.175 ± 0.038
0.55TyrTrp: 0.55 ± 0.015
1.859TyrTyr: 1.859 ± 0.036
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5481 proteins (2048369 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski