Amino acid dipepetide frequency for Tortoise microvirus 79

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.064AlaAla: 10.064 ± 1.915
0.53AlaCys: 0.53 ± 0.474
4.237AlaAsp: 4.237 ± 1.536
13.771AlaGlu: 13.771 ± 2.486
3.708AlaPhe: 3.708 ± 1.569
7.945AlaGly: 7.945 ± 2.743
2.648AlaHis: 2.648 ± 1.463
4.237AlaIle: 4.237 ± 1.311
4.767AlaLys: 4.767 ± 2.317
3.178AlaLeu: 3.178 ± 1.494
4.237AlaMet: 4.237 ± 1.097
3.708AlaAsn: 3.708 ± 1.645
5.826AlaPro: 5.826 ± 1.341
2.119AlaGln: 2.119 ± 1.058
5.297AlaArg: 5.297 ± 1.427
5.297AlaSer: 5.297 ± 1.832
3.708AlaThr: 3.708 ± 1.23
7.945AlaVal: 7.945 ± 1.287
1.059AlaTrp: 1.059 ± 0.735
2.648AlaTyr: 2.648 ± 1.118
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.059CysIle: 1.059 ± 0.949
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.53CysMet: 0.53 ± 0.632
0.53CysAsn: 0.53 ± 0.633
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.589CysArg: 1.589 ± 1.423
0.53CysSer: 0.53 ± 0.687
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.53CysTrp: 0.53 ± 0.474
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.767AspAla: 4.767 ± 0.882
0.53AspCys: 0.53 ± 0.474
1.059AspAsp: 1.059 ± 0.762
4.237AspGlu: 4.237 ± 1.086
2.119AspPhe: 2.119 ± 0.811
4.237AspGly: 4.237 ± 1.413
2.119AspHis: 2.119 ± 0.721
4.767AspIle: 4.767 ± 1.236
1.589AspLys: 1.589 ± 0.929
3.178AspLeu: 3.178 ± 1.217
2.119AspMet: 2.119 ± 1.15
1.589AspAsn: 1.589 ± 0.962
2.119AspPro: 2.119 ± 0.869
2.119AspGln: 2.119 ± 0.817
2.648AspArg: 2.648 ± 1.229
1.059AspSer: 1.059 ± 0.658
2.648AspThr: 2.648 ± 0.946
4.237AspVal: 4.237 ± 1.141
1.589AspTrp: 1.589 ± 0.592
1.059AspTyr: 1.059 ± 0.584
0.0AspXaa: 0.0 ± 0.0
Glu
10.064GluAla: 10.064 ± 1.961
0.0GluCys: 0.0 ± 0.0
1.589GluAsp: 1.589 ± 0.793
5.297GluGlu: 5.297 ± 2.575
2.648GluPhe: 2.648 ± 1.849
5.297GluGly: 5.297 ± 1.919
1.589GluHis: 1.589 ± 0.976
3.178GluIle: 3.178 ± 1.059
0.53GluLys: 0.53 ± 0.524
5.826GluLeu: 5.826 ± 1.973
2.119GluMet: 2.119 ± 0.972
2.119GluAsn: 2.119 ± 1.523
2.648GluPro: 2.648 ± 1.64
2.119GluGln: 2.119 ± 1.602
4.237GluArg: 4.237 ± 1.457
4.237GluSer: 4.237 ± 1.021
3.178GluThr: 3.178 ± 1.051
8.475GluVal: 8.475 ± 1.757
2.119GluTrp: 2.119 ± 0.851
2.119GluTyr: 2.119 ± 1.377
0.0GluXaa: 0.0 ± 0.0
Phe
4.237PheAla: 4.237 ± 1.152
0.0PheCys: 0.0 ± 0.0
1.589PheAsp: 1.589 ± 0.793
2.648PheGlu: 2.648 ± 1.073
0.53PhePhe: 0.53 ± 0.381
4.237PheGly: 4.237 ± 1.238
0.53PheHis: 0.53 ± 0.474
0.53PheIle: 0.53 ± 0.652
1.589PheLys: 1.589 ± 0.592
3.708PheLeu: 3.708 ± 1.082
0.53PheMet: 0.53 ± 0.652
2.119PheAsn: 2.119 ± 1.3
0.53PhePro: 0.53 ± 0.474
2.648PheGln: 2.648 ± 0.727
1.059PheArg: 1.059 ± 0.949
1.059PheSer: 1.059 ± 0.48
2.648PheThr: 2.648 ± 1.193
1.059PheVal: 1.059 ± 0.907
1.589PheTrp: 1.589 ± 0.929
1.589PheTyr: 1.589 ± 0.788
0.0PheXaa: 0.0 ± 0.0
Gly
9.534GlyAla: 9.534 ± 3.344
0.0GlyCys: 0.0 ± 0.0
3.708GlyAsp: 3.708 ± 1.052
3.708GlyGlu: 3.708 ± 1.83
2.648GlyPhe: 2.648 ± 0.837
11.123GlyGly: 11.123 ± 4.044
2.648GlyHis: 2.648 ± 1.158
2.648GlyIle: 2.648 ± 1.158
2.119GlyLys: 2.119 ± 0.818
8.475GlyLeu: 8.475 ± 2.05
2.119GlyMet: 2.119 ± 1.144
2.119GlyAsn: 2.119 ± 0.824
3.178GlyPro: 3.178 ± 1.436
3.708GlyGln: 3.708 ± 0.45
5.826GlyArg: 5.826 ± 2.478
5.297GlySer: 5.297 ± 1.437
4.767GlyThr: 4.767 ± 1.15
3.708GlyVal: 3.708 ± 0.73
0.0GlyTrp: 0.0 ± 0.0
0.53GlyTyr: 0.53 ± 0.381
0.0GlyXaa: 0.0 ± 0.0
His
2.648HisAla: 2.648 ± 0.971
0.0HisCys: 0.0 ± 0.0
0.53HisAsp: 0.53 ± 0.381
2.119HisGlu: 2.119 ± 0.992
0.53HisPhe: 0.53 ± 0.687
1.059HisGly: 1.059 ± 0.735
0.53HisHis: 0.53 ± 0.381
2.648HisIle: 2.648 ± 1.152
0.53HisLys: 0.53 ± 0.524
0.53HisLeu: 0.53 ± 0.477
1.589HisMet: 1.589 ± 0.976
1.059HisAsn: 1.059 ± 0.762
3.708HisPro: 3.708 ± 1.282
2.648HisGln: 2.648 ± 0.805
3.178HisArg: 3.178 ± 1.552
1.059HisSer: 1.059 ± 0.575
1.059HisThr: 1.059 ± 0.757
1.059HisVal: 1.059 ± 0.607
1.589HisTrp: 1.589 ± 0.592
1.059HisTyr: 1.059 ± 0.528
0.0HisXaa: 0.0 ± 0.0
Ile
4.237IleAla: 4.237 ± 1.616
0.53IleCys: 0.53 ± 0.687
2.119IleAsp: 2.119 ± 0.818
4.767IleGlu: 4.767 ± 1.147
0.0IlePhe: 0.0 ± 0.0
3.178IleGly: 3.178 ± 1.582
1.059IleHis: 1.059 ± 0.621
3.178IleIle: 3.178 ± 0.975
1.589IleLys: 1.589 ± 1.031
4.237IleLeu: 4.237 ± 1.018
2.648IleMet: 2.648 ± 0.805
1.059IleAsn: 1.059 ± 0.762
3.178IlePro: 3.178 ± 0.894
1.059IleGln: 1.059 ± 0.528
1.589IleArg: 1.589 ± 1.184
1.589IleSer: 1.589 ± 1.234
1.589IleThr: 1.589 ± 0.708
3.178IleVal: 3.178 ± 1.859
1.059IleTrp: 1.059 ± 0.48
0.53IleTyr: 0.53 ± 0.687
0.0IleXaa: 0.0 ± 0.0
Lys
3.708LysAla: 3.708 ± 0.939
0.0LysCys: 0.0 ± 0.0
1.589LysAsp: 1.589 ± 0.973
1.059LysGlu: 1.059 ± 0.801
2.119LysPhe: 2.119 ± 1.377
1.059LysGly: 1.059 ± 0.949
0.53LysHis: 0.53 ± 0.381
1.059LysIle: 1.059 ± 0.575
1.589LysLys: 1.589 ± 0.956
3.708LysLeu: 3.708 ± 1.797
3.178LysMet: 3.178 ± 1.401
1.589LysAsn: 1.589 ± 1.031
2.119LysPro: 2.119 ± 1.09
2.648LysGln: 2.648 ± 1.287
2.648LysArg: 2.648 ± 1.073
3.708LysSer: 3.708 ± 2.23
2.119LysThr: 2.119 ± 0.869
2.648LysVal: 2.648 ± 1.113
0.53LysTrp: 0.53 ± 0.524
1.059LysTyr: 1.059 ± 0.949
0.0LysXaa: 0.0 ± 0.0
Leu
7.945LeuAla: 7.945 ± 2.357
0.0LeuCys: 0.0 ± 0.0
5.297LeuAsp: 5.297 ± 0.977
4.237LeuGlu: 4.237 ± 3.028
2.648LeuPhe: 2.648 ± 1.017
6.356LeuGly: 6.356 ± 2.709
2.119LeuHis: 2.119 ± 0.721
3.708LeuIle: 3.708 ± 1.003
4.237LeuLys: 4.237 ± 1.54
3.708LeuLeu: 3.708 ± 1.193
2.648LeuMet: 2.648 ± 0.971
1.589LeuAsn: 1.589 ± 1.142
3.708LeuPro: 3.708 ± 1.625
2.648LeuGln: 2.648 ± 1.501
5.826LeuArg: 5.826 ± 1.834
8.475LeuSer: 8.475 ± 1.42
6.886LeuThr: 6.886 ± 1.581
4.767LeuVal: 4.767 ± 1.528
1.059LeuTrp: 1.059 ± 0.575
0.53LeuTyr: 0.53 ± 0.524
0.0LeuXaa: 0.0 ± 0.0
Met
4.237MetAla: 4.237 ± 0.579
1.059MetCys: 1.059 ± 0.672
2.119MetAsp: 2.119 ± 1.051
2.119MetGlu: 2.119 ± 0.741
3.178MetPhe: 3.178 ± 0.995
1.059MetGly: 1.059 ± 0.48
1.589MetHis: 1.589 ± 0.844
1.589MetIle: 1.589 ± 1.487
0.0MetLys: 0.0 ± 0.0
1.589MetLeu: 1.589 ± 0.592
1.059MetMet: 1.059 ± 0.755
1.589MetAsn: 1.589 ± 0.823
3.708MetPro: 3.708 ± 0.869
1.589MetGln: 1.589 ± 0.662
1.589MetArg: 1.589 ± 1.331
4.237MetSer: 4.237 ± 1.256
1.059MetThr: 1.059 ± 0.907
2.119MetVal: 2.119 ± 0.672
0.53MetTrp: 0.53 ± 0.524
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.119AsnAla: 2.119 ± 0.931
0.0AsnCys: 0.0 ± 0.0
0.53AsnAsp: 0.53 ± 0.474
1.589AsnGlu: 1.589 ± 0.722
0.53AsnPhe: 0.53 ± 0.633
3.708AsnGly: 3.708 ± 0.45
1.059AsnHis: 1.059 ± 0.762
0.53AsnIle: 0.53 ± 0.381
0.53AsnLys: 0.53 ± 0.565
4.767AsnLeu: 4.767 ± 1.46
1.059AsnMet: 1.059 ± 0.762
2.119AsnAsn: 2.119 ± 1.071
3.708AsnPro: 3.708 ± 1.311
1.059AsnGln: 1.059 ± 0.48
5.297AsnArg: 5.297 ± 1.928
1.589AsnSer: 1.589 ± 1.142
1.589AsnThr: 1.589 ± 0.708
3.708AsnVal: 3.708 ± 1.286
2.648AsnTrp: 2.648 ± 1.438
0.53AsnTyr: 0.53 ± 0.477
0.0AsnXaa: 0.0 ± 0.0
Pro
5.297ProAla: 5.297 ± 2.082
0.0ProCys: 0.0 ± 0.0
4.237ProAsp: 4.237 ± 1.875
2.119ProGlu: 2.119 ± 0.949
0.53ProPhe: 0.53 ± 0.381
3.178ProGly: 3.178 ± 1.573
2.648ProHis: 2.648 ± 1.011
2.648ProIle: 2.648 ± 1.279
2.119ProLys: 2.119 ± 1.726
9.004ProLeu: 9.004 ± 2.705
1.059ProMet: 1.059 ± 1.047
3.178ProAsn: 3.178 ± 1.855
1.589ProPro: 1.589 ± 0.973
3.708ProGln: 3.708 ± 1.579
3.178ProArg: 3.178 ± 1.393
3.178ProSer: 3.178 ± 0.799
1.589ProThr: 1.589 ± 0.811
4.237ProVal: 4.237 ± 2.0
1.059ProTrp: 1.059 ± 0.658
2.648ProTyr: 2.648 ± 0.803
0.0ProXaa: 0.0 ± 0.0
Gln
4.767GlnAla: 4.767 ± 0.957
0.53GlnCys: 0.53 ± 0.474
2.119GlnAsp: 2.119 ± 0.673
2.119GlnGlu: 2.119 ± 0.851
1.589GlnPhe: 1.589 ± 0.787
2.119GlnGly: 2.119 ± 0.778
0.53GlnHis: 0.53 ± 0.477
2.648GlnIle: 2.648 ± 1.614
4.237GlnLys: 4.237 ± 1.74
3.178GlnLeu: 3.178 ± 0.918
2.648GlnMet: 2.648 ± 1.229
1.589GlnAsn: 1.589 ± 1.432
1.589GlnPro: 1.589 ± 0.869
2.119GlnGln: 2.119 ± 1.954
4.237GlnArg: 4.237 ± 1.955
3.178GlnSer: 3.178 ± 1.098
1.059GlnThr: 1.059 ± 0.955
4.237GlnVal: 4.237 ± 1.121
0.53GlnTrp: 0.53 ± 0.474
1.589GlnTyr: 1.589 ± 0.823
0.0GlnXaa: 0.0 ± 0.0
Arg
5.826ArgAla: 5.826 ± 2.08
0.53ArgCys: 0.53 ± 0.474
5.297ArgAsp: 5.297 ± 1.573
3.708ArgGlu: 3.708 ± 1.184
3.178ArgPhe: 3.178 ± 1.27
2.648ArgGly: 2.648 ± 1.001
0.53ArgHis: 0.53 ± 0.381
2.648ArgIle: 2.648 ± 0.769
5.297ArgLys: 5.297 ± 1.306
5.826ArgLeu: 5.826 ± 1.565
2.648ArgMet: 2.648 ± 1.452
3.178ArgAsn: 3.178 ± 1.415
3.178ArgPro: 3.178 ± 2.468
3.178ArgGln: 3.178 ± 1.461
8.475ArgArg: 8.475 ± 5.604
5.826ArgSer: 5.826 ± 1.471
1.589ArgThr: 1.589 ± 0.626
4.237ArgVal: 4.237 ± 1.49
0.0ArgTrp: 0.0 ± 0.0
4.237ArgTyr: 4.237 ± 1.55
0.0ArgXaa: 0.0 ± 0.0
Ser
4.767SerAla: 4.767 ± 1.331
0.0SerCys: 0.0 ± 0.0
4.767SerAsp: 4.767 ± 1.551
5.826SerGlu: 5.826 ± 1.236
2.648SerPhe: 2.648 ± 0.761
4.767SerGly: 4.767 ± 1.593
2.119SerHis: 2.119 ± 0.921
1.589SerIle: 1.589 ± 0.722
4.767SerLys: 4.767 ± 2.172
4.237SerLeu: 4.237 ± 0.895
1.059SerMet: 1.059 ± 0.575
1.589SerAsn: 1.589 ± 0.722
4.237SerPro: 4.237 ± 1.806
2.648SerGln: 2.648 ± 1.358
4.237SerArg: 4.237 ± 1.781
4.767SerSer: 4.767 ± 1.86
3.178SerThr: 3.178 ± 1.048
3.708SerVal: 3.708 ± 0.816
1.589SerTrp: 1.589 ± 0.674
2.119SerTyr: 2.119 ± 0.895
0.0SerXaa: 0.0 ± 0.0
Thr
3.178ThrAla: 3.178 ± 1.414
0.0ThrCys: 0.0 ± 0.0
1.589ThrAsp: 1.589 ± 0.793
3.178ThrGlu: 3.178 ± 1.331
0.53ThrPhe: 0.53 ± 0.474
6.356ThrGly: 6.356 ± 1.565
1.589ThrHis: 1.589 ± 0.674
1.589ThrIle: 1.589 ± 0.63
0.53ThrLys: 0.53 ± 0.381
5.297ThrLeu: 5.297 ± 2.024
2.119ThrMet: 2.119 ± 1.316
1.059ThrAsn: 1.059 ± 0.745
3.708ThrPro: 3.708 ± 1.041
2.648ThrGln: 2.648 ± 1.02
2.119ThrArg: 2.119 ± 1.191
2.119ThrSer: 2.119 ± 1.49
3.178ThrThr: 3.178 ± 1.737
2.648ThrVal: 2.648 ± 0.91
0.0ThrTrp: 0.0 ± 0.0
2.119ThrTyr: 2.119 ± 1.078
0.0ThrXaa: 0.0 ± 0.0
Val
5.826ValAla: 5.826 ± 2.472
0.53ValCys: 0.53 ± 0.474
5.826ValAsp: 5.826 ± 1.745
2.648ValGlu: 2.648 ± 1.434
3.708ValPhe: 3.708 ± 1.052
4.767ValGly: 4.767 ± 1.45
3.178ValHis: 3.178 ± 0.998
1.589ValIle: 1.589 ± 0.817
1.059ValLys: 1.059 ± 0.801
3.708ValLeu: 3.708 ± 0.757
1.589ValMet: 1.589 ± 0.823
3.178ValAsn: 3.178 ± 1.047
5.826ValPro: 5.826 ± 2.458
4.767ValGln: 4.767 ± 1.141
5.826ValArg: 5.826 ± 1.407
5.826ValSer: 5.826 ± 1.166
3.708ValThr: 3.708 ± 0.873
3.708ValVal: 3.708 ± 1.449
2.119ValTrp: 2.119 ± 0.673
1.059ValTyr: 1.059 ± 0.757
0.0ValXaa: 0.0 ± 0.0
Trp
0.53TrpAla: 0.53 ± 0.381
0.53TrpCys: 0.53 ± 0.633
1.589TrpAsp: 1.589 ± 1.046
3.178TrpGlu: 3.178 ± 1.348
0.0TrpPhe: 0.0 ± 0.0
1.059TrpGly: 1.059 ± 0.575
0.53TrpHis: 0.53 ± 0.474
0.0TrpIle: 0.0 ± 0.0
2.119TrpLys: 2.119 ± 0.985
1.589TrpLeu: 1.589 ± 0.788
0.53TrpMet: 0.53 ± 0.477
2.119TrpAsn: 2.119 ± 0.959
1.589TrpPro: 1.589 ± 0.592
1.589TrpGln: 1.589 ± 1.423
2.119TrpArg: 2.119 ± 0.995
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.059TrpVal: 1.059 ± 0.584
0.0TrpTrp: 0.0 ± 0.0
0.53TrpTyr: 0.53 ± 0.652
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.178TyrAla: 3.178 ± 1.369
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
1.059TyrGlu: 1.059 ± 0.528
1.589TyrPhe: 1.589 ± 1.082
3.708TyrGly: 3.708 ± 1.423
1.589TyrHis: 1.589 ± 0.679
0.53TyrIle: 0.53 ± 0.474
0.0TyrLys: 0.0 ± 0.0
2.648TyrLeu: 2.648 ± 0.913
0.0TyrMet: 0.0 ± 0.0
1.589TyrAsn: 1.589 ± 0.722
1.059TyrPro: 1.059 ± 0.769
1.589TyrGln: 1.589 ± 0.976
1.059TyrArg: 1.059 ± 0.762
1.589TyrSer: 1.589 ± 0.683
0.0TyrThr: 0.0 ± 0.0
3.708TyrVal: 3.708 ± 1.026
1.059TyrTrp: 1.059 ± 0.949
0.53TyrTyr: 0.53 ± 0.474
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1889 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski