Amino acid dipepetide frequency for Abalone shriveling syndrome-associated virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.08AlaAla: 8.08 ± 1.597
0.643AlaCys: 0.643 ± 0.283
5.05AlaAsp: 5.05 ± 0.886
5.05AlaGlu: 5.05 ± 1.044
2.479AlaPhe: 2.479 ± 0.423
6.244AlaGly: 6.244 ± 0.831
0.918AlaHis: 0.918 ± 0.29
4.591AlaIle: 4.591 ± 0.556
4.407AlaLys: 4.407 ± 0.701
8.631AlaLeu: 8.631 ± 0.921
1.653AlaMet: 1.653 ± 0.329
5.234AlaAsn: 5.234 ± 0.636
3.122AlaPro: 3.122 ± 0.582
2.846AlaGln: 2.846 ± 0.472
3.765AlaArg: 3.765 ± 0.528
7.346AlaSer: 7.346 ± 0.839
6.336AlaThr: 6.336 ± 0.869
5.785AlaVal: 5.785 ± 0.791
0.092AlaTrp: 0.092 ± 0.092
2.295AlaTyr: 2.295 ± 0.462
0.0AlaXaa: 0.0 ± 0.0
Cys
0.367CysAla: 0.367 ± 0.194
0.459CysCys: 0.459 ± 0.245
0.918CysAsp: 0.918 ± 0.354
0.275CysGlu: 0.275 ± 0.145
0.459CysPhe: 0.459 ± 0.207
0.551CysGly: 0.551 ± 0.233
0.367CysHis: 0.367 ± 0.24
0.551CysIle: 0.551 ± 0.213
0.551CysLys: 0.551 ± 0.268
0.643CysLeu: 0.643 ± 0.184
0.092CysMet: 0.092 ± 0.097
0.643CysAsn: 0.643 ± 0.225
0.275CysPro: 0.275 ± 0.168
0.184CysGln: 0.184 ± 0.128
0.551CysArg: 0.551 ± 0.262
0.367CysSer: 0.367 ± 0.231
0.459CysThr: 0.459 ± 0.202
0.275CysVal: 0.275 ± 0.177
0.0CysTrp: 0.0 ± 0.0
0.275CysTyr: 0.275 ± 0.154
0.0CysXaa: 0.0 ± 0.0
Asp
4.224AspAla: 4.224 ± 0.73
0.551AspCys: 0.551 ± 0.21
4.132AspAsp: 4.132 ± 0.653
2.846AspGlu: 2.846 ± 0.499
3.856AspPhe: 3.856 ± 0.877
5.325AspGly: 5.325 ± 1.244
1.01AspHis: 1.01 ± 0.435
4.775AspIle: 4.775 ± 0.782
2.571AspLys: 2.571 ± 0.371
5.05AspLeu: 5.05 ± 0.497
0.643AspMet: 0.643 ± 0.258
2.663AspAsn: 2.663 ± 0.41
2.295AspPro: 2.295 ± 0.398
1.836AspGln: 1.836 ± 0.362
2.571AspArg: 2.571 ± 0.47
4.683AspSer: 4.683 ± 0.502
2.02AspThr: 2.02 ± 0.494
4.04AspVal: 4.04 ± 0.625
0.643AspTrp: 0.643 ± 0.231
2.387AspTyr: 2.387 ± 0.382
0.0AspXaa: 0.0 ± 0.0
Glu
3.305GluAla: 3.305 ± 0.537
0.092GluCys: 0.092 ± 0.077
3.305GluAsp: 3.305 ± 0.669
3.765GluGlu: 3.765 ± 0.635
3.397GluPhe: 3.397 ± 0.558
2.112GluGly: 2.112 ± 0.315
1.194GluHis: 1.194 ± 0.474
3.581GluIle: 3.581 ± 0.525
3.397GluLys: 3.397 ± 0.541
5.601GluLeu: 5.601 ± 0.773
0.826GluMet: 0.826 ± 0.284
2.755GluAsn: 2.755 ± 0.466
1.561GluPro: 1.561 ± 0.329
2.02GluGln: 2.02 ± 0.42
2.387GluArg: 2.387 ± 0.627
2.295GluSer: 2.295 ± 0.491
2.571GluThr: 2.571 ± 0.38
2.755GluVal: 2.755 ± 0.681
0.367GluTrp: 0.367 ± 0.189
1.836GluTyr: 1.836 ± 0.464
0.0GluXaa: 0.0 ± 0.0
Phe
4.132PheAla: 4.132 ± 0.755
0.735PheCys: 0.735 ± 0.3
2.479PheAsp: 2.479 ± 0.464
1.561PheGlu: 1.561 ± 0.363
3.948PhePhe: 3.948 ± 0.613
3.03PheGly: 3.03 ± 0.519
0.735PheHis: 0.735 ± 0.3
3.305PheIle: 3.305 ± 0.484
2.938PheLys: 2.938 ± 0.538
5.325PheLeu: 5.325 ± 0.651
0.918PheMet: 0.918 ± 0.297
3.581PheAsn: 3.581 ± 0.494
2.02PhePro: 2.02 ± 0.466
0.826PheGln: 0.826 ± 0.221
1.745PheArg: 1.745 ± 0.421
5.234PheSer: 5.234 ± 0.519
3.673PheThr: 3.673 ± 0.514
3.03PheVal: 3.03 ± 0.361
0.367PheTrp: 0.367 ± 0.188
2.663PheTyr: 2.663 ± 0.651
0.0PheXaa: 0.0 ± 0.0
Gly
5.417GlyAla: 5.417 ± 0.919
0.275GlyCys: 0.275 ± 0.158
3.581GlyAsp: 3.581 ± 0.888
1.836GlyGlu: 1.836 ± 0.413
3.489GlyPhe: 3.489 ± 0.516
3.122GlyGly: 3.122 ± 0.617
0.184GlyHis: 0.184 ± 0.138
4.591GlyIle: 4.591 ± 0.596
4.499GlyLys: 4.499 ± 0.601
4.683GlyLeu: 4.683 ± 0.587
1.194GlyMet: 1.194 ± 0.309
3.489GlyAsn: 3.489 ± 0.549
0.918GlyPro: 0.918 ± 0.281
1.836GlyGln: 1.836 ± 0.381
2.479GlyArg: 2.479 ± 0.491
6.427GlySer: 6.427 ± 0.698
4.866GlyThr: 4.866 ± 0.984
4.315GlyVal: 4.315 ± 0.634
0.367GlyTrp: 0.367 ± 0.169
2.663GlyTyr: 2.663 ± 0.382
0.0GlyXaa: 0.0 ± 0.0
His
1.01HisAla: 1.01 ± 0.262
0.275HisCys: 0.275 ± 0.146
0.826HisAsp: 0.826 ± 0.303
1.469HisGlu: 1.469 ± 0.489
0.735HisPhe: 0.735 ± 0.312
0.459HisGly: 0.459 ± 0.174
0.367HisHis: 0.367 ± 0.251
1.469HisIle: 1.469 ± 0.428
0.643HisLys: 0.643 ± 0.242
1.653HisLeu: 1.653 ± 0.37
0.551HisMet: 0.551 ± 0.266
0.643HisAsn: 0.643 ± 0.229
1.102HisPro: 1.102 ± 0.398
0.459HisGln: 0.459 ± 0.19
0.551HisArg: 0.551 ± 0.241
0.459HisSer: 0.459 ± 0.223
0.367HisThr: 0.367 ± 0.216
1.102HisVal: 1.102 ± 0.293
0.0HisTrp: 0.0 ± 0.0
0.367HisTyr: 0.367 ± 0.215
0.0HisXaa: 0.0 ± 0.0
Ile
5.509IleAla: 5.509 ± 0.633
0.918IleCys: 0.918 ± 0.31
4.866IleAsp: 4.866 ± 0.897
3.581IleGlu: 3.581 ± 0.634
2.938IlePhe: 2.938 ± 0.536
3.03IleGly: 3.03 ± 0.488
1.102IleHis: 1.102 ± 0.274
3.305IleIle: 3.305 ± 0.725
3.948IleLys: 3.948 ± 0.629
6.978IleLeu: 6.978 ± 0.788
0.275IleMet: 0.275 ± 0.13
5.142IleAsn: 5.142 ± 0.738
2.938IlePro: 2.938 ± 0.655
2.02IleGln: 2.02 ± 0.349
2.938IleArg: 2.938 ± 0.51
6.244IleSer: 6.244 ± 0.714
3.948IleThr: 3.948 ± 0.643
5.509IleVal: 5.509 ± 0.592
0.275IleTrp: 0.275 ± 0.152
1.745IleTyr: 1.745 ± 0.36
0.0IleXaa: 0.0 ± 0.0
Lys
4.407LysAla: 4.407 ± 0.517
0.367LysCys: 0.367 ± 0.213
2.755LysAsp: 2.755 ± 0.486
2.204LysGlu: 2.204 ± 0.592
3.305LysPhe: 3.305 ± 0.54
1.377LysGly: 1.377 ± 0.34
0.826LysHis: 0.826 ± 0.247
3.856LysIle: 3.856 ± 0.657
4.958LysLys: 4.958 ± 0.827
6.06LysLeu: 6.06 ± 0.785
1.469LysMet: 1.469 ± 0.331
5.05LysAsn: 5.05 ± 0.786
2.387LysPro: 2.387 ± 0.371
2.295LysGln: 2.295 ± 0.496
2.387LysArg: 2.387 ± 0.419
3.305LysSer: 3.305 ± 0.562
4.775LysThr: 4.775 ± 0.554
4.315LysVal: 4.315 ± 0.871
0.367LysTrp: 0.367 ± 0.181
2.755LysTyr: 2.755 ± 0.505
0.0LysXaa: 0.0 ± 0.0
Leu
9.274LeuAla: 9.274 ± 1.159
0.826LeuCys: 0.826 ± 0.375
5.968LeuAsp: 5.968 ± 0.853
4.683LeuGlu: 4.683 ± 0.807
3.673LeuPhe: 3.673 ± 0.403
6.152LeuGly: 6.152 ± 0.928
2.387LeuHis: 2.387 ± 0.511
5.325LeuIle: 5.325 ± 0.554
6.152LeuLys: 6.152 ± 0.802
8.631LeuLeu: 8.631 ± 0.863
1.745LeuMet: 1.745 ± 0.385
4.224LeuAsn: 4.224 ± 0.67
3.856LeuPro: 3.856 ± 0.478
3.214LeuGln: 3.214 ± 0.526
4.224LeuArg: 4.224 ± 0.508
7.07LeuSer: 7.07 ± 0.773
6.611LeuThr: 6.611 ± 0.687
5.785LeuVal: 5.785 ± 0.616
0.643LeuTrp: 0.643 ± 0.209
1.928LeuTyr: 1.928 ± 0.361
0.0LeuXaa: 0.0 ± 0.0
Met
1.194MetAla: 1.194 ± 0.269
0.0MetCys: 0.0 ± 0.0
1.01MetAsp: 1.01 ± 0.284
1.01MetGlu: 1.01 ± 0.313
0.735MetPhe: 0.735 ± 0.25
0.643MetGly: 0.643 ± 0.213
0.367MetHis: 0.367 ± 0.172
1.745MetIle: 1.745 ± 0.342
1.102MetLys: 1.102 ± 0.332
1.653MetLeu: 1.653 ± 0.378
0.367MetMet: 0.367 ± 0.162
1.194MetAsn: 1.194 ± 0.308
0.367MetPro: 0.367 ± 0.161
0.551MetGln: 0.551 ± 0.17
1.102MetArg: 1.102 ± 0.293
1.561MetSer: 1.561 ± 0.397
1.653MetThr: 1.653 ± 0.352
1.285MetVal: 1.285 ± 0.299
0.275MetTrp: 0.275 ± 0.198
0.551MetTyr: 0.551 ± 0.227
0.0MetXaa: 0.0 ± 0.0
Asn
4.958AsnAla: 4.958 ± 0.663
0.184AsnCys: 0.184 ± 0.181
2.663AsnAsp: 2.663 ± 0.555
2.846AsnGlu: 2.846 ± 0.42
2.571AsnPhe: 2.571 ± 0.508
3.765AsnGly: 3.765 ± 0.89
0.735AsnHis: 0.735 ± 0.308
5.968AsnIle: 5.968 ± 0.761
3.03AsnLys: 3.03 ± 0.461
4.407AsnLeu: 4.407 ± 0.717
0.918AsnMet: 0.918 ± 0.267
4.958AsnAsn: 4.958 ± 0.707
2.204AsnPro: 2.204 ± 0.416
2.479AsnGln: 2.479 ± 0.451
2.479AsnArg: 2.479 ± 0.423
5.142AsnSer: 5.142 ± 0.715
4.499AsnThr: 4.499 ± 0.429
2.938AsnVal: 2.938 ± 0.405
0.367AsnTrp: 0.367 ± 0.182
2.02AsnTyr: 2.02 ± 0.435
0.0AsnXaa: 0.0 ± 0.0
Pro
4.407ProAla: 4.407 ± 0.668
0.275ProCys: 0.275 ± 0.165
2.295ProAsp: 2.295 ± 0.504
2.295ProGlu: 2.295 ± 0.449
1.653ProPhe: 1.653 ± 0.361
1.469ProGly: 1.469 ± 0.356
0.459ProHis: 0.459 ± 0.19
1.745ProIle: 1.745 ± 0.357
2.204ProLys: 2.204 ± 0.378
2.938ProLeu: 2.938 ± 0.42
0.551ProMet: 0.551 ± 0.201
1.836ProAsn: 1.836 ± 0.436
2.02ProPro: 2.02 ± 0.542
1.285ProGln: 1.285 ± 0.325
1.469ProArg: 1.469 ± 0.354
2.938ProSer: 2.938 ± 0.552
3.03ProThr: 3.03 ± 0.598
3.765ProVal: 3.765 ± 0.482
0.367ProTrp: 0.367 ± 0.16
1.194ProTyr: 1.194 ± 0.396
0.0ProXaa: 0.0 ± 0.0
Gln
2.387GlnAla: 2.387 ± 0.408
0.092GlnCys: 0.092 ± 0.093
1.194GlnAsp: 1.194 ± 0.29
1.836GlnGlu: 1.836 ± 0.441
1.653GlnPhe: 1.653 ± 0.525
2.204GlnGly: 2.204 ± 0.489
0.551GlnHis: 0.551 ± 0.212
2.387GlnIle: 2.387 ± 0.477
2.755GlnLys: 2.755 ± 0.546
3.03GlnLeu: 3.03 ± 0.536
0.643GlnMet: 0.643 ± 0.266
1.194GlnAsn: 1.194 ± 0.347
2.204GlnPro: 2.204 ± 0.375
2.295GlnGln: 2.295 ± 0.536
1.285GlnArg: 1.285 ± 0.38
2.938GlnSer: 2.938 ± 0.414
2.295GlnThr: 2.295 ± 0.599
1.745GlnVal: 1.745 ± 0.425
0.275GlnTrp: 0.275 ± 0.147
1.561GlnTyr: 1.561 ± 0.418
0.0GlnXaa: 0.0 ± 0.0
Arg
3.581ArgAla: 3.581 ± 0.705
0.551ArgCys: 0.551 ± 0.31
2.02ArgAsp: 2.02 ± 0.519
2.204ArgGlu: 2.204 ± 0.629
2.755ArgPhe: 2.755 ± 0.538
3.122ArgGly: 3.122 ± 0.487
0.551ArgHis: 0.551 ± 0.209
2.571ArgIle: 2.571 ± 0.472
2.846ArgLys: 2.846 ± 0.42
4.315ArgLeu: 4.315 ± 0.809
1.194ArgMet: 1.194 ± 0.252
2.479ArgAsn: 2.479 ± 0.427
1.194ArgPro: 1.194 ± 0.333
2.02ArgGln: 2.02 ± 0.34
1.928ArgArg: 1.928 ± 0.518
3.397ArgSer: 3.397 ± 0.485
2.663ArgThr: 2.663 ± 0.697
2.571ArgVal: 2.571 ± 0.357
0.184ArgTrp: 0.184 ± 0.13
1.469ArgTyr: 1.469 ± 0.323
0.0ArgXaa: 0.0 ± 0.0
Ser
7.162SerAla: 7.162 ± 0.871
0.735SerCys: 0.735 ± 0.273
4.315SerAsp: 4.315 ± 0.572
3.856SerGlu: 3.856 ± 0.748
5.417SerPhe: 5.417 ± 0.71
6.427SerGly: 6.427 ± 0.656
1.102SerHis: 1.102 ± 0.349
5.968SerIle: 5.968 ± 0.608
3.673SerLys: 3.673 ± 0.546
6.611SerLeu: 6.611 ± 0.585
2.112SerMet: 2.112 ± 0.56
4.04SerAsn: 4.04 ± 0.682
2.846SerPro: 2.846 ± 0.623
2.387SerGln: 2.387 ± 0.546
4.315SerArg: 4.315 ± 0.713
9.09SerSer: 9.09 ± 1.136
6.703SerThr: 6.703 ± 0.876
3.673SerVal: 3.673 ± 0.596
0.367SerTrp: 0.367 ± 0.179
2.479SerTyr: 2.479 ± 0.48
0.0SerXaa: 0.0 ± 0.0
Thr
6.519ThrAla: 6.519 ± 0.808
0.367ThrCys: 0.367 ± 0.194
4.866ThrAsp: 4.866 ± 0.931
3.122ThrGlu: 3.122 ± 0.43
3.305ThrPhe: 3.305 ± 0.58
4.591ThrGly: 4.591 ± 0.64
0.551ThrHis: 0.551 ± 0.239
5.601ThrIle: 5.601 ± 0.775
3.948ThrLys: 3.948 ± 0.625
4.958ThrLeu: 4.958 ± 0.553
1.469ThrMet: 1.469 ± 0.4
4.407ThrAsn: 4.407 ± 0.748
2.846ThrPro: 2.846 ± 0.405
1.745ThrGln: 1.745 ± 0.338
2.112ThrArg: 2.112 ± 0.333
5.417ThrSer: 5.417 ± 0.709
5.693ThrThr: 5.693 ± 0.76
5.05ThrVal: 5.05 ± 1.138
0.643ThrTrp: 0.643 ± 0.214
2.204ThrTyr: 2.204 ± 0.497
0.0ThrXaa: 0.0 ± 0.0
Val
6.336ValAla: 6.336 ± 0.826
0.367ValCys: 0.367 ± 0.215
4.132ValAsp: 4.132 ± 0.669
3.214ValGlu: 3.214 ± 0.388
3.581ValPhe: 3.581 ± 0.578
4.315ValGly: 4.315 ± 0.706
0.643ValHis: 0.643 ± 0.306
2.938ValIle: 2.938 ± 0.605
3.673ValLys: 3.673 ± 0.551
7.162ValLeu: 7.162 ± 0.817
1.01ValMet: 1.01 ± 0.245
3.214ValAsn: 3.214 ± 0.415
2.938ValPro: 2.938 ± 0.578
2.112ValGln: 2.112 ± 0.352
2.938ValArg: 2.938 ± 0.69
5.142ValSer: 5.142 ± 0.648
4.315ValThr: 4.315 ± 0.706
5.601ValVal: 5.601 ± 0.881
0.275ValTrp: 0.275 ± 0.131
2.295ValTyr: 2.295 ± 0.364
0.0ValXaa: 0.0 ± 0.0
Trp
0.275TrpAla: 0.275 ± 0.149
0.0TrpCys: 0.0 ± 0.0
0.367TrpAsp: 0.367 ± 0.186
0.275TrpGlu: 0.275 ± 0.16
0.551TrpPhe: 0.551 ± 0.227
0.367TrpGly: 0.367 ± 0.22
0.092TrpHis: 0.092 ± 0.109
0.367TrpIle: 0.367 ± 0.164
0.184TrpLys: 0.184 ± 0.136
0.367TrpLeu: 0.367 ± 0.15
0.275TrpMet: 0.275 ± 0.151
0.184TrpAsn: 0.184 ± 0.124
0.092TrpPro: 0.092 ± 0.082
0.459TrpGln: 0.459 ± 0.232
0.275TrpArg: 0.275 ± 0.176
0.735TrpSer: 0.735 ± 0.246
0.643TrpThr: 0.643 ± 0.167
0.367TrpVal: 0.367 ± 0.194
0.0TrpTrp: 0.0 ± 0.0
0.459TrpTyr: 0.459 ± 0.221
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.02TyrAla: 2.02 ± 0.409
0.551TyrCys: 0.551 ± 0.247
1.377TyrAsp: 1.377 ± 0.342
1.194TyrGlu: 1.194 ± 0.213
1.745TyrPhe: 1.745 ± 0.436
1.928TyrGly: 1.928 ± 0.443
0.367TyrHis: 0.367 ± 0.206
2.571TyrIle: 2.571 ± 0.592
1.745TyrLys: 1.745 ± 0.417
3.673TyrLeu: 3.673 ± 0.459
0.367TyrMet: 0.367 ± 0.147
2.204TyrAsn: 2.204 ± 0.616
1.01TyrPro: 1.01 ± 0.322
1.653TyrGln: 1.653 ± 0.432
2.112TyrArg: 2.112 ± 0.516
3.581TyrSer: 3.581 ± 0.604
2.295TyrThr: 2.295 ± 0.699
2.295TyrVal: 2.295 ± 0.413
0.459TyrTrp: 0.459 ± 0.172
1.928TyrTyr: 1.928 ± 0.597
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 31 proteins (10892 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski