Amino acid dipepetide frequency for Arthrobotrys flagrans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.083AlaAla: 8.083 ± 0.067	0.896AlaCys: 0.896 ± 0.017	3.714AlaAsp: 3.714 ± 0.028	4.92AlaGlu: 4.92 ± 0.049	2.769AlaPhe: 2.769 ± 0.026	5.318AlaGly: 5.318 ± 0.036	1.408AlaHis: 1.408 ± 0.018	4.211AlaIle: 4.211 ± 0.032	4.266AlaLys: 4.266 ± 0.042	6.558AlaLeu: 6.558 ± 0.048	1.674AlaMet: 1.674 ± 0.017	2.84AlaAsn: 2.84 ± 0.024	4.639AlaPro: 4.639 ± 0.047	2.855AlaGln: 2.855 ± 0.034	4.223AlaArg: 4.223 ± 0.033	6.557AlaSer: 6.557 ± 0.044	5.196AlaThr: 5.196 ± 0.041	4.887AlaVal: 4.887 ± 0.037	0.919AlaTrp: 0.919 ± 0.014	1.998AlaTyr: 1.998 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.8CysAla: 0.8 ± 0.017	0.237CysCys: 0.237 ± 0.008	0.614CysAsp: 0.614 ± 0.012	0.614CysGlu: 0.614 ± 0.014	0.494CysPhe: 0.494 ± 0.011	0.95CysGly: 0.95 ± 0.018	0.283CysHis: 0.283 ± 0.007	0.671CysIle: 0.671 ± 0.012	0.577CysLys: 0.577 ± 0.012	1.101CysLeu: 1.101 ± 0.015	0.246CysMet: 0.246 ± 0.006	0.46CysAsn: 0.46 ± 0.011	0.665CysPro: 0.665 ± 0.015	0.414CysGln: 0.414 ± 0.01	0.684CysArg: 0.684 ± 0.011	0.828CysSer: 0.828 ± 0.017	0.659CysThr: 0.659 ± 0.012	0.711CysVal: 0.711 ± 0.013	0.184CysTrp: 0.184 ± 0.006	0.381CysTyr: 0.381 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.021AspAla: 4.021 ± 0.03	0.613AspCys: 0.613 ± 0.013	4.412AspAsp: 4.412 ± 0.046	4.755AspGlu: 4.755 ± 0.047	2.217AspPhe: 2.217 ± 0.018	4.158AspGly: 4.158 ± 0.038	1.109AspHis: 1.109 ± 0.017	3.416AspIle: 3.416 ± 0.026	2.628AspLys: 2.628 ± 0.031	4.79AspLeu: 4.79 ± 0.034	1.183AspMet: 1.183 ± 0.015	1.99AspAsn: 1.99 ± 0.021	3.267AspPro: 3.267 ± 0.028	1.628AspGln: 1.628 ± 0.018	2.857AspArg: 2.857 ± 0.034	3.956AspSer: 3.956 ± 0.035	2.983AspThr: 2.983 ± 0.021	3.483AspVal: 3.483 ± 0.03	0.817AspTrp: 0.817 ± 0.014	1.662AspTyr: 1.662 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.242GluAla: 5.242 ± 0.053	0.626GluCys: 0.626 ± 0.012	4.605GluAsp: 4.605 ± 0.04	6.871GluGlu: 6.871 ± 0.089	2.19GluPhe: 2.19 ± 0.022	4.221GluGly: 4.221 ± 0.036	1.256GluHis: 1.256 ± 0.016	3.593GluIle: 3.593 ± 0.027	4.461GluLys: 4.461 ± 0.043	5.204GluLeu: 5.204 ± 0.041	1.49GluMet: 1.49 ± 0.017	2.654GluAsn: 2.654 ± 0.025	3.033GluPro: 3.033 ± 0.048	2.271GluGln: 2.271 ± 0.03	4.028GluArg: 4.028 ± 0.041	4.333GluSer: 4.333 ± 0.038	3.74GluThr: 3.74 ± 0.038	3.883GluVal: 3.883 ± 0.036	0.854GluTrp: 0.854 ± 0.014	1.925GluTyr: 1.925 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.687PheAla: 2.687 ± 0.029	0.534PheCys: 0.534 ± 0.011	2.264PheAsp: 2.264 ± 0.021	2.337PheGlu: 2.337 ± 0.025	1.549PhePhe: 1.549 ± 0.021	2.871PheGly: 2.871 ± 0.034	0.85PheHis: 0.85 ± 0.012	1.828PheIle: 1.828 ± 0.023	1.827PheLys: 1.827 ± 0.02	3.312PheLeu: 3.312 ± 0.029	0.755PheMet: 0.755 ± 0.011	1.488PheAsn: 1.488 ± 0.019	1.959PhePro: 1.959 ± 0.02	1.381PheGln: 1.381 ± 0.019	1.926PheArg: 1.926 ± 0.02	2.97PheSer: 2.97 ± 0.027	2.262PheThr: 2.262 ± 0.024	2.278PheVal: 2.278 ± 0.024	0.589PheTrp: 0.589 ± 0.011	1.126PheTyr: 1.126 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.773GlyAla: 4.773 ± 0.037	0.852GlyCys: 0.852 ± 0.016	3.695GlyAsp: 3.695 ± 0.033	3.949GlyGlu: 3.949 ± 0.029	2.811GlyPhe: 2.811 ± 0.031	6.453GlyGly: 6.453 ± 0.069	1.502GlyHis: 1.502 ± 0.021	3.657GlyIle: 3.657 ± 0.03	3.936GlyLys: 3.936 ± 0.034	5.572GlyLeu: 5.572 ± 0.037	1.505GlyMet: 1.505 ± 0.019	2.867GlyAsn: 2.867 ± 0.036	3.15GlyPro: 3.15 ± 0.036	2.281GlyGln: 2.281 ± 0.027	4.032GlyArg: 4.032 ± 0.031	5.717GlySer: 5.717 ± 0.044	4.011GlyThr: 4.011 ± 0.036	4.454GlyVal: 4.454 ± 0.036	1.125GlyTrp: 1.125 ± 0.016	2.295GlyTyr: 2.295 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.45HisAla: 1.45 ± 0.019	0.289HisCys: 0.289 ± 0.009	1.134HisAsp: 1.134 ± 0.017	1.222HisGlu: 1.222 ± 0.017	0.851HisPhe: 0.851 ± 0.013	1.501HisGly: 1.501 ± 0.018	0.91HisHis: 0.91 ± 0.019	1.217HisIle: 1.217 ± 0.018	0.984HisLys: 0.984 ± 0.016	2.079HisLeu: 2.079 ± 0.022	0.437HisMet: 0.437 ± 0.01	0.822HisAsn: 0.822 ± 0.013	1.616HisPro: 1.616 ± 0.02	0.994HisGln: 0.994 ± 0.018	1.419HisArg: 1.419 ± 0.019	1.707HisSer: 1.707 ± 0.025	1.228HisThr: 1.228 ± 0.018	1.179HisVal: 1.179 ± 0.015	0.284HisTrp: 0.284 ± 0.009	0.675HisTyr: 0.675 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.021IleAla: 4.021 ± 0.031	0.747IleCys: 0.747 ± 0.012	3.056IleAsp: 3.056 ± 0.023	3.232IleGlu: 3.232 ± 0.029	2.09IlePhe: 2.09 ± 0.024	3.259IleGly: 3.259 ± 0.027	1.216IleHis: 1.216 ± 0.018	2.814IleIle: 2.814 ± 0.027	2.749IleLys: 2.749 ± 0.024	4.852IleLeu: 4.852 ± 0.034	1.015IleMet: 1.015 ± 0.016	2.067IleAsn: 2.067 ± 0.021	3.513IlePro: 3.513 ± 0.029	1.964IleGln: 1.964 ± 0.021	2.979IleArg: 2.979 ± 0.026	4.335IleSer: 4.335 ± 0.033	3.318IleThr: 3.318 ± 0.031	3.275IleVal: 3.275 ± 0.03	0.706IleTrp: 0.706 ± 0.013	1.538IleTyr: 1.538 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.5LysAla: 4.5 ± 0.041	0.586LysCys: 0.586 ± 0.011	3.201LysAsp: 3.201 ± 0.028	4.274LysGlu: 4.274 ± 0.04	1.806LysPhe: 1.806 ± 0.02	3.401LysGly: 3.401 ± 0.031	1.141LysHis: 1.141 ± 0.016	2.868LysIle: 2.868 ± 0.025	4.359LysLys: 4.359 ± 0.05	4.624LysLeu: 4.624 ± 0.033	1.143LysMet: 1.143 ± 0.016	2.161LysAsn: 2.161 ± 0.024	3.197LysPro: 3.197 ± 0.033	1.94LysGln: 1.94 ± 0.02	3.813LysArg: 3.813 ± 0.033	4.084LysSer: 4.084 ± 0.03	3.285LysThr: 3.285 ± 0.032	3.239LysVal: 3.239 ± 0.029	0.726LysTrp: 0.726 ± 0.012	1.67LysTyr: 1.67 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	6.803LeuAla: 6.803 ± 0.045	1.055LeuCys: 1.055 ± 0.015	4.787LeuAsp: 4.787 ± 0.034	5.875LeuGlu: 5.875 ± 0.046	3.115LeuPhe: 3.115 ± 0.029	5.399LeuGly: 5.399 ± 0.039	1.999LeuHis: 1.999 ± 0.023	3.915LeuIle: 3.915 ± 0.033	4.908LeuLys: 4.908 ± 0.031	7.801LeuLeu: 7.801 ± 0.065	1.645LeuMet: 1.645 ± 0.017	3.295LeuAsn: 3.295 ± 0.028	5.412LeuPro: 5.412 ± 0.05	3.569LeuGln: 3.569 ± 0.029	5.266LeuArg: 5.266 ± 0.036	7.0LeuSer: 7.0 ± 0.048	4.756LeuThr: 4.756 ± 0.038	4.932LeuVal: 4.932 ± 0.036	1.078LeuTrp: 1.078 ± 0.018	2.282LeuTyr: 2.282 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	1.898MetAla: 1.898 ± 0.021	0.21MetCys: 0.21 ± 0.007	1.188MetAsp: 1.188 ± 0.018	1.374MetGlu: 1.374 ± 0.016	0.72MetPhe: 0.72 ± 0.013	1.386MetGly: 1.386 ± 0.018	0.429MetHis: 0.429 ± 0.01	0.986MetIle: 0.986 ± 0.014	1.177MetLys: 1.177 ± 0.015	1.659MetLeu: 1.659 ± 0.018	0.559MetMet: 0.559 ± 0.012	0.792MetAsn: 0.792 ± 0.014	1.147MetPro: 1.147 ± 0.018	0.786MetGln: 0.786 ± 0.014	1.147MetArg: 1.147 ± 0.015	1.729MetSer: 1.729 ± 0.02	1.195MetThr: 1.195 ± 0.015	1.266MetVal: 1.266 ± 0.017	0.238MetTrp: 0.238 ± 0.007	0.502MetTyr: 0.502 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.948AsnAla: 2.948 ± 0.025	0.484AsnCys: 0.484 ± 0.01	2.028AsnAsp: 2.028 ± 0.017	2.168AsnGlu: 2.168 ± 0.021	1.547AsnPhe: 1.547 ± 0.018	3.195AsnGly: 3.195 ± 0.037	0.91AsnHis: 0.91 ± 0.015	2.397AsnIle: 2.397 ± 0.025	1.832AsnLys: 1.832 ± 0.022	3.524AsnLeu: 3.524 ± 0.033	0.833AsnMet: 0.833 ± 0.015	1.851AsnAsn: 1.851 ± 0.032	2.832AsnPro: 2.832 ± 0.027	1.423AsnGln: 1.423 ± 0.02	2.12AsnArg: 2.12 ± 0.024	3.138AsnSer: 3.138 ± 0.031	2.497AsnThr: 2.497 ± 0.023	2.332AsnVal: 2.332 ± 0.021	0.569AsnTrp: 0.569 ± 0.011	1.16AsnTyr: 1.16 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.962ProAla: 4.962 ± 0.042	0.466ProCys: 0.466 ± 0.014	2.944ProAsp: 2.944 ± 0.028	3.989ProGlu: 3.989 ± 0.039	1.981ProPhe: 1.981 ± 0.022	3.861ProGly: 3.861 ± 0.037	1.283ProHis: 1.283 ± 0.018	2.925ProIle: 2.925 ± 0.026	3.214ProLys: 3.214 ± 0.031	4.609ProLeu: 4.609 ± 0.03	1.026ProMet: 1.026 ± 0.016	2.457ProAsn: 2.457 ± 0.025	6.289ProPro: 6.289 ± 0.094	2.609ProGln: 2.609 ± 0.041	3.291ProArg: 3.291 ± 0.036	6.19ProSer: 6.19 ± 0.052	4.822ProThr: 4.822 ± 0.043	3.71ProVal: 3.71 ± 0.039	0.637ProTrp: 0.637 ± 0.011	1.557ProTyr: 1.557 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	2.953GlnAla: 2.953 ± 0.037	0.397GlnCys: 0.397 ± 0.01	1.822GlnAsp: 1.822 ± 0.021	2.36GlnGlu: 2.36 ± 0.027	1.253GlnPhe: 1.253 ± 0.015	2.163GlnGly: 2.163 ± 0.026	0.958GlnHis: 0.958 ± 0.018	1.97GlnIle: 1.97 ± 0.019	2.191GlnLys: 2.191 ± 0.024	3.164GlnLeu: 3.164 ± 0.032	0.81GlnMet: 0.81 ± 0.015	1.669GlnAsn: 1.669 ± 0.023	2.497GlnPro: 2.497 ± 0.037	2.558GlnGln: 2.558 ± 0.067	2.335GlnArg: 2.335 ± 0.03	2.876GlnSer: 2.876 ± 0.032	2.335GlnThr: 2.335 ± 0.024	1.98GlnVal: 1.98 ± 0.022	0.467GlnTrp: 0.467 ± 0.01	1.129GlnTyr: 1.129 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.031ArgAla: 4.031 ± 0.031	0.641ArgCys: 0.641 ± 0.012	3.195ArgAsp: 3.195 ± 0.03	3.884ArgGlu: 3.884 ± 0.039	2.074ArgPhe: 2.074 ± 0.023	3.694ArgGly: 3.694 ± 0.035	1.37ArgHis: 1.37 ± 0.019	3.013ArgIle: 3.013 ± 0.027	3.913ArgLys: 3.913 ± 0.031	5.001ArgLeu: 5.001 ± 0.038	1.274ArgMet: 1.274 ± 0.017	2.432ArgAsn: 2.432 ± 0.023	3.261ArgPro: 3.261 ± 0.03	2.353ArgGln: 2.353 ± 0.023	4.938ArgArg: 4.938 ± 0.046	4.597ArgSer: 4.597 ± 0.039	3.276ArgThr: 3.276 ± 0.028	3.163ArgVal: 3.163 ± 0.028	0.825ArgTrp: 0.825 ± 0.014	1.726ArgTyr: 1.726 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	5.94SerAla: 5.94 ± 0.039	0.825SerCys: 0.825 ± 0.014	4.114SerAsp: 4.114 ± 0.036	4.378SerGlu: 4.378 ± 0.034	2.961SerPhe: 2.961 ± 0.03	5.577SerGly: 5.577 ± 0.041	1.877SerHis: 1.877 ± 0.022	4.354SerIle: 4.354 ± 0.03	4.306SerLys: 4.306 ± 0.034	6.901SerLeu: 6.901 ± 0.04	1.552SerMet: 1.552 ± 0.018	3.343SerAsn: 3.343 ± 0.027	5.683SerPro: 5.683 ± 0.056	3.125SerGln: 3.125 ± 0.034	4.886SerArg: 4.886 ± 0.04	9.083SerSer: 9.083 ± 0.071	6.036SerThr: 6.036 ± 0.053	4.395SerVal: 4.395 ± 0.035	0.968SerTrp: 0.968 ± 0.013	2.172SerTyr: 2.172 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.189ThrAla: 5.189 ± 0.036	0.762ThrCys: 0.762 ± 0.015	2.922ThrAsp: 2.922 ± 0.025	3.435ThrGlu: 3.435 ± 0.032	2.291ThrPhe: 2.291 ± 0.023	4.199ThrGly: 4.199 ± 0.04	1.229ThrHis: 1.229 ± 0.018	3.547ThrIle: 3.547 ± 0.028	3.129ThrLys: 3.129 ± 0.03	5.207ThrLeu: 5.207 ± 0.038	1.098ThrMet: 1.098 ± 0.015	2.386ThrAsn: 2.386 ± 0.024	4.971ThrPro: 4.971 ± 0.048	2.018ThrGln: 2.018 ± 0.021	3.088ThrArg: 3.088 ± 0.025	5.879ThrSer: 5.879 ± 0.048	5.574ThrThr: 5.574 ± 0.089	3.941ThrVal: 3.941 ± 0.035	0.75ThrTrp: 0.75 ± 0.013	1.678ThrTyr: 1.678 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.76ValAla: 4.76 ± 0.042	0.736ValCys: 0.736 ± 0.012	3.594ValAsp: 3.594 ± 0.03	4.287ValGlu: 4.287 ± 0.043	2.317ValPhe: 2.317 ± 0.024	3.998ValGly: 3.998 ± 0.033	1.232ValHis: 1.232 ± 0.02	3.081ValIle: 3.081 ± 0.027	3.333ValLys: 3.333 ± 0.029	5.129ValLeu: 5.129 ± 0.04	1.235ValMet: 1.235 ± 0.016	2.314ValAsn: 2.314 ± 0.022	3.617ValPro: 3.617 ± 0.03	2.119ValGln: 2.119 ± 0.019	3.174ValArg: 3.174 ± 0.03	4.427ValSer: 4.427 ± 0.033	3.599ValThr: 3.599 ± 0.036	4.288ValVal: 4.288 ± 0.04	0.789ValTrp: 0.789 ± 0.014	1.755ValTyr: 1.755 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.916TrpAla: 0.916 ± 0.014	0.189TrpCys: 0.189 ± 0.006	0.863TrpAsp: 0.863 ± 0.014	0.858TrpGlu: 0.858 ± 0.013	0.517TrpPhe: 0.517 ± 0.01	0.926TrpGly: 0.926 ± 0.014	0.288TrpHis: 0.288 ± 0.009	0.72TrpIle: 0.72 ± 0.013	0.873TrpLys: 0.873 ± 0.015	1.123TrpLeu: 1.123 ± 0.017	0.342TrpMet: 0.342 ± 0.008	0.602TrpAsn: 0.602 ± 0.011	0.487TrpPro: 0.487 ± 0.01	0.464TrpGln: 0.464 ± 0.011	0.835TrpArg: 0.835 ± 0.013	0.921TrpSer: 0.921 ± 0.015	0.778TrpThr: 0.778 ± 0.014	0.815TrpVal: 0.815 ± 0.013	0.263TrpTrp: 0.263 ± 0.008	0.431TrpTyr: 0.431 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.955TyrAla: 1.955 ± 0.023	0.428TyrCys: 0.428 ± 0.01	1.791TyrAsp: 1.791 ± 0.019	1.7TyrGlu: 1.7 ± 0.019	1.242TyrPhe: 1.242 ± 0.017	2.106TyrGly: 2.106 ± 0.028	0.748TyrHis: 0.748 ± 0.012	1.564TyrIle: 1.564 ± 0.02	1.355TyrLys: 1.355 ± 0.018	2.684TyrLeu: 2.684 ± 0.026	0.565TyrMet: 0.565 ± 0.012	1.297TyrAsn: 1.297 ± 0.018	1.588TyrPro: 1.588 ± 0.02	1.134TyrGln: 1.134 ± 0.016	1.618TyrArg: 1.618 ± 0.019	2.146TyrSer: 2.146 ± 0.023	1.744TyrThr: 1.744 ± 0.02	1.574TyrVal: 1.574 ± 0.019	0.422TyrTrp: 0.422 ± 0.01	1.019TyrTyr: 1.019 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10325 proteins (5006540 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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