Amino acid dipepetide frequency for Mesosutterella multiformis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.083AlaAla: 15.083 ± 0.249	1.258AlaCys: 1.258 ± 0.046	5.539AlaAsp: 5.539 ± 0.093	7.069AlaGlu: 7.069 ± 0.114	4.093AlaPhe: 4.093 ± 0.088	8.699AlaGly: 8.699 ± 0.128	1.679AlaHis: 1.679 ± 0.053	5.699AlaIle: 5.699 ± 0.098	5.708AlaLys: 5.708 ± 0.109	10.249AlaLeu: 10.249 ± 0.127	2.794AlaMet: 2.794 ± 0.062	2.645AlaAsn: 2.645 ± 0.061	4.376AlaPro: 4.376 ± 0.104	2.964AlaGln: 2.964 ± 0.077	5.597AlaArg: 5.597 ± 0.108	6.811AlaSer: 6.811 ± 0.119	4.34AlaThr: 4.34 ± 0.101	8.284AlaVal: 8.284 ± 0.113	1.296AlaTrp: 1.296 ± 0.039	2.349AlaTyr: 2.349 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.982CysAla: 0.982 ± 0.039	0.163CysCys: 0.163 ± 0.017	0.578CysAsp: 0.578 ± 0.029	0.586CysGlu: 0.586 ± 0.032	0.432CysPhe: 0.432 ± 0.029	1.281CysGly: 1.281 ± 0.051	0.312CysHis: 0.312 ± 0.026	0.526CysIle: 0.526 ± 0.03	0.305CysLys: 0.305 ± 0.02	1.038CysLeu: 1.038 ± 0.039	0.235CysMet: 0.235 ± 0.02	0.275CysAsn: 0.275 ± 0.02	0.711CysPro: 0.711 ± 0.038	0.268CysGln: 0.268 ± 0.02	0.837CysArg: 0.837 ± 0.034	0.713CysSer: 0.713 ± 0.036	0.584CysThr: 0.584 ± 0.03	0.819CysVal: 0.819 ± 0.033	0.129CysTrp: 0.129 ± 0.012	0.336CysTyr: 0.336 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	5.72AspAla: 5.72 ± 0.094	0.618AspCys: 0.618 ± 0.031	2.527AspAsp: 2.527 ± 0.074	3.577AspGlu: 3.577 ± 0.072	2.475AspPhe: 2.475 ± 0.057	4.029AspGly: 4.029 ± 0.09	1.038AspHis: 1.038 ± 0.039	3.125AspIle: 3.125 ± 0.071	2.339AspLys: 2.339 ± 0.067	5.083AspLeu: 5.083 ± 0.078	1.242AspMet: 1.242 ± 0.045	1.387AspAsn: 1.387 ± 0.046	3.549AspPro: 3.549 ± 0.072	1.614AspGln: 1.614 ± 0.052	3.492AspArg: 3.492 ± 0.076	2.949AspSer: 2.949 ± 0.067	2.901AspThr: 2.901 ± 0.071	3.519AspVal: 3.519 ± 0.078	0.928AspTrp: 0.928 ± 0.039	1.533AspTyr: 1.533 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	7.25GluAla: 7.25 ± 0.142	0.517GluCys: 0.517 ± 0.029	3.284GluAsp: 3.284 ± 0.079	4.831GluGlu: 4.831 ± 0.109	2.241GluPhe: 2.241 ± 0.063	4.36GluGly: 4.36 ± 0.089	1.208GluHis: 1.208 ± 0.042	3.757GluIle: 3.757 ± 0.071	4.673GluLys: 4.673 ± 0.077	5.726GluLeu: 5.726 ± 0.092	1.594GluMet: 1.594 ± 0.043	2.411GluAsn: 2.411 ± 0.059	2.41GluPro: 2.41 ± 0.058	1.84GluGln: 1.84 ± 0.058	3.818GluArg: 3.818 ± 0.075	3.833GluSer: 3.833 ± 0.082	3.724GluThr: 3.724 ± 0.079	4.052GluVal: 4.052 ± 0.074	0.72GluTrp: 0.72 ± 0.033	1.305GluTyr: 1.305 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	4.023PheAla: 4.023 ± 0.088	0.537PheCys: 0.537 ± 0.029	2.391PheAsp: 2.391 ± 0.066	2.187PheGlu: 2.187 ± 0.055	1.973PhePhe: 1.973 ± 0.066	3.529PheGly: 3.529 ± 0.079	0.806PheHis: 0.806 ± 0.039	2.293PheIle: 2.293 ± 0.07	1.431PheLys: 1.431 ± 0.046	3.806PheLeu: 3.806 ± 0.085	0.917PheMet: 0.917 ± 0.034	1.268PheAsn: 1.268 ± 0.044	1.893PhePro: 1.893 ± 0.051	0.987PheGln: 0.987 ± 0.039	2.386PheArg: 2.386 ± 0.058	2.937PheSer: 2.937 ± 0.073	2.381PheThr: 2.381 ± 0.065	2.663PheVal: 2.663 ± 0.066	0.569PheTrp: 0.569 ± 0.03	1.138PheTyr: 1.138 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	7.245GlyAla: 7.245 ± 0.117	1.139GlyCys: 1.139 ± 0.047	3.979GlyAsp: 3.979 ± 0.088	4.438GlyGlu: 4.438 ± 0.091	3.632GlyPhe: 3.632 ± 0.073	5.886GlyGly: 5.886 ± 0.122	1.635GlyHis: 1.635 ± 0.052	5.424GlyIle: 5.424 ± 0.087	4.846GlyLys: 4.846 ± 0.096	7.576GlyLeu: 7.576 ± 0.104	2.169GlyMet: 2.169 ± 0.063	2.757GlyAsn: 2.757 ± 0.069	2.455GlyPro: 2.455 ± 0.075	1.992GlyGln: 1.992 ± 0.06	4.648GlyArg: 4.648 ± 0.086	5.043GlySer: 5.043 ± 0.111	4.916GlyThr: 4.916 ± 0.111	6.113GlyVal: 6.113 ± 0.113	1.143GlyTrp: 1.143 ± 0.044	2.461GlyTyr: 2.461 ± 0.069	0.0GlyXaa: 0.0 ± 0.0
His	1.68HisAla: 1.68 ± 0.054	0.292HisCys: 0.292 ± 0.02	1.006HisAsp: 1.006 ± 0.038	1.078HisGlu: 1.078 ± 0.042	0.911HisPhe: 0.911 ± 0.036	1.601HisGly: 1.601 ± 0.047	0.569HisHis: 0.569 ± 0.031	1.074HisIle: 1.074 ± 0.044	0.681HisLys: 0.681 ± 0.032	1.82HisLeu: 1.82 ± 0.055	0.476HisMet: 0.476 ± 0.026	0.526HisAsn: 0.526 ± 0.027	1.347HisPro: 1.347 ± 0.043	0.628HisGln: 0.628 ± 0.025	1.142HisArg: 1.142 ± 0.041	1.082HisSer: 1.082 ± 0.036	0.931HisThr: 0.931 ± 0.034	1.237HisVal: 1.237 ± 0.04	0.316HisTrp: 0.316 ± 0.023	0.568HisTyr: 0.568 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.57IleAla: 6.57 ± 0.109	0.707IleCys: 0.707 ± 0.031	3.299IleAsp: 3.299 ± 0.063	3.634IleGlu: 3.634 ± 0.086	2.145IlePhe: 2.145 ± 0.053	4.781IleGly: 4.781 ± 0.106	1.164IleHis: 1.164 ± 0.038	2.449IleIle: 2.449 ± 0.063	1.911IleLys: 1.911 ± 0.054	5.392IleLeu: 5.392 ± 0.105	1.054IleMet: 1.054 ± 0.043	1.717IleAsn: 1.717 ± 0.057	3.316IlePro: 3.316 ± 0.069	1.672IleGln: 1.672 ± 0.053	4.233IleArg: 4.233 ± 0.084	3.649IleSer: 3.649 ± 0.078	3.292IleThr: 3.292 ± 0.067	4.049IleVal: 4.049 ± 0.09	0.616IleTrp: 0.616 ± 0.031	1.367IleTyr: 1.367 ± 0.046	0.0IleXaa: 0.0 ± 0.0
Lys	6.185LysAla: 6.185 ± 0.098	0.409LysCys: 0.409 ± 0.029	2.87LysAsp: 2.87 ± 0.073	3.373LysGlu: 3.373 ± 0.079	1.536LysPhe: 1.536 ± 0.047	3.857LysGly: 3.857 ± 0.078	0.851LysHis: 0.851 ± 0.034	2.808LysIle: 2.808 ± 0.068	3.617LysLys: 3.617 ± 0.09	4.641LysLeu: 4.641 ± 0.078	1.308LysMet: 1.308 ± 0.049	2.145LysAsn: 2.145 ± 0.064	2.737LysPro: 2.737 ± 0.059	1.445LysGln: 1.445 ± 0.052	3.041LysArg: 3.041 ± 0.067	2.948LysSer: 2.948 ± 0.064	3.493LysThr: 3.493 ± 0.08	3.163LysVal: 3.163 ± 0.078	0.56LysTrp: 0.56 ± 0.033	1.085LysTyr: 1.085 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	9.95LeuAla: 9.95 ± 0.122	1.037LeuCys: 1.037 ± 0.04	4.892LeuAsp: 4.892 ± 0.077	5.618LeuGlu: 5.618 ± 0.104	3.843LeuPhe: 3.843 ± 0.081	7.371LeuGly: 7.371 ± 0.107	1.646LeuHis: 1.646 ± 0.046	5.488LeuIle: 5.488 ± 0.092	5.253LeuLys: 5.253 ± 0.092	8.596LeuLeu: 8.596 ± 0.155	2.441LeuMet: 2.441 ± 0.065	2.88LeuAsn: 2.88 ± 0.064	5.196LeuPro: 5.196 ± 0.083	2.815LeuGln: 2.815 ± 0.077	5.676LeuArg: 5.676 ± 0.101	6.926LeuSer: 6.926 ± 0.112	5.917LeuThr: 5.917 ± 0.09	6.079LeuVal: 6.079 ± 0.094	1.075LeuTrp: 1.075 ± 0.047	2.333LeuTyr: 2.333 ± 0.069	0.0LeuXaa: 0.0 ± 0.0
Met	2.594MetAla: 2.594 ± 0.063	0.18MetCys: 0.18 ± 0.015	1.193MetAsp: 1.193 ± 0.043	1.339MetGlu: 1.339 ± 0.044	0.643MetPhe: 0.643 ± 0.026	1.884MetGly: 1.884 ± 0.053	0.415MetHis: 0.415 ± 0.025	1.387MetIle: 1.387 ± 0.043	1.825MetLys: 1.825 ± 0.044	2.189MetLeu: 2.189 ± 0.058	0.749MetMet: 0.749 ± 0.038	0.985MetAsn: 0.985 ± 0.038	1.384MetPro: 1.384 ± 0.048	0.846MetGln: 0.846 ± 0.036	1.418MetArg: 1.418 ± 0.044	1.577MetSer: 1.577 ± 0.041	1.891MetThr: 1.891 ± 0.046	1.616MetVal: 1.616 ± 0.05	0.19MetTrp: 0.19 ± 0.017	0.38MetTyr: 0.38 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.223AsnAla: 3.223 ± 0.072	0.36AsnCys: 0.36 ± 0.026	1.5AsnAsp: 1.5 ± 0.048	1.725AsnGlu: 1.725 ± 0.053	1.213AsnPhe: 1.213 ± 0.041	2.89AsnGly: 2.89 ± 0.068	0.674AsnHis: 0.674 ± 0.03	1.64AsnIle: 1.64 ± 0.057	1.252AsnLys: 1.252 ± 0.045	2.978AsnLeu: 2.978 ± 0.08	0.697AsnMet: 0.697 ± 0.033	0.905AsnAsn: 0.905 ± 0.042	2.313AsnPro: 2.313 ± 0.059	1.014AsnGln: 1.014 ± 0.034	2.068AsnArg: 2.068 ± 0.053	1.863AsnSer: 1.863 ± 0.058	1.788AsnThr: 1.788 ± 0.062	2.056AsnVal: 2.056 ± 0.058	0.374AsnTrp: 0.374 ± 0.024	0.89AsnTyr: 0.89 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	5.509ProAla: 5.509 ± 0.111	0.456ProCys: 0.456 ± 0.023	3.357ProAsp: 3.357 ± 0.082	4.658ProGlu: 4.658 ± 0.096	1.997ProPhe: 1.997 ± 0.056	4.043ProGly: 4.043 ± 0.077	0.844ProHis: 0.844 ± 0.032	2.482ProIle: 2.482 ± 0.06	2.588ProLys: 2.588 ± 0.066	4.195ProLeu: 4.195 ± 0.081	1.163ProMet: 1.163 ± 0.044	1.438ProAsn: 1.438 ± 0.05	1.611ProPro: 1.611 ± 0.058	1.412ProGln: 1.412 ± 0.043	2.333ProArg: 2.333 ± 0.064	2.643ProSer: 2.643 ± 0.066	2.284ProThr: 2.284 ± 0.054	4.216ProVal: 4.216 ± 0.087	0.637ProTrp: 0.637 ± 0.032	1.334ProTyr: 1.334 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.925GlnAla: 2.925 ± 0.071	0.28GlnCys: 0.28 ± 0.019	1.283GlnAsp: 1.283 ± 0.045	1.589GlnGlu: 1.589 ± 0.048	1.075GlnPhe: 1.075 ± 0.04	2.116GlnGly: 2.116 ± 0.056	0.548GlnHis: 0.548 ± 0.029	1.866GlnIle: 1.866 ± 0.051	2.067GlnLys: 2.067 ± 0.063	2.611GlnLeu: 2.611 ± 0.061	0.875GlnMet: 0.875 ± 0.04	1.075GlnAsn: 1.075 ± 0.04	1.281GlnPro: 1.281 ± 0.042	0.992GlnGln: 0.992 ± 0.042	1.521GlnArg: 1.521 ± 0.05	1.742GlnSer: 1.742 ± 0.056	1.74GlnThr: 1.74 ± 0.046	2.179GlnVal: 2.179 ± 0.061	0.364GlnTrp: 0.364 ± 0.023	0.917GlnTyr: 0.917 ± 0.046	0.0GlnXaa: 0.0 ± 0.0
Arg	5.385ArgAla: 5.385 ± 0.099	0.517ArgCys: 0.517 ± 0.029	3.33ArgAsp: 3.33 ± 0.074	4.348ArgGlu: 4.348 ± 0.094	2.675ArgPhe: 2.675 ± 0.07	4.01ArgGly: 4.01 ± 0.1	1.326ArgHis: 1.326 ± 0.04	3.753ArgIle: 3.753 ± 0.071	3.139ArgLys: 3.139 ± 0.061	5.929ArgLeu: 5.929 ± 0.117	1.653ArgMet: 1.653 ± 0.05	2.057ArgAsn: 2.057 ± 0.049	2.567ArgPro: 2.567 ± 0.064	1.871ArgGln: 1.871 ± 0.063	3.969ArgArg: 3.969 ± 0.091	3.466ArgSer: 3.466 ± 0.074	3.177ArgThr: 3.177 ± 0.071	4.352ArgVal: 4.352 ± 0.086	0.728ArgTrp: 0.728 ± 0.032	1.901ArgTyr: 1.901 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	6.317SerAla: 6.317 ± 0.116	0.647SerCys: 0.647 ± 0.033	3.911SerAsp: 3.911 ± 0.089	3.957SerGlu: 3.957 ± 0.082	2.558SerPhe: 2.558 ± 0.057	5.961SerGly: 5.961 ± 0.111	1.208SerHis: 1.208 ± 0.044	3.329SerIle: 3.329 ± 0.069	2.308SerLys: 2.308 ± 0.054	6.339SerLeu: 6.339 ± 0.091	1.446SerMet: 1.446 ± 0.044	1.619SerAsn: 1.619 ± 0.048	3.032SerPro: 3.032 ± 0.07	1.791SerGln: 1.791 ± 0.056	4.069SerArg: 4.069 ± 0.084	3.799SerSer: 3.799 ± 0.092	2.989SerThr: 2.989 ± 0.077	4.746SerVal: 4.746 ± 0.088	0.824SerTrp: 0.824 ± 0.032	1.561SerTyr: 1.561 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	5.917ThrAla: 5.917 ± 0.11	0.535ThrCys: 0.535 ± 0.032	3.121ThrAsp: 3.121 ± 0.07	3.549ThrGlu: 3.549 ± 0.071	2.029ThrPhe: 2.029 ± 0.057	5.339ThrGly: 5.339 ± 0.121	1.081ThrHis: 1.081 ± 0.044	2.907ThrIle: 2.907 ± 0.073	2.238ThrLys: 2.238 ± 0.055	6.016ThrLeu: 6.016 ± 0.095	1.122ThrMet: 1.122 ± 0.042	1.581ThrAsn: 1.581 ± 0.049	3.59ThrPro: 3.59 ± 0.072	1.411ThrGln: 1.411 ± 0.045	3.068ThrArg: 3.068 ± 0.069	3.022ThrSer: 3.022 ± 0.072	2.659ThrThr: 2.659 ± 0.072	4.635ThrVal: 4.635 ± 0.098	0.693ThrTrp: 0.693 ± 0.032	1.366ThrTyr: 1.366 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	6.472ValAla: 6.472 ± 0.104	0.935ValCys: 0.935 ± 0.034	3.517ValAsp: 3.517 ± 0.089	3.763ValGlu: 3.763 ± 0.074	2.959ValPhe: 2.959 ± 0.072	4.767ValGly: 4.767 ± 0.094	1.218ValHis: 1.218 ± 0.038	4.928ValIle: 4.928 ± 0.1	4.114ValLys: 4.114 ± 0.085	6.875ValLeu: 6.875 ± 0.091	1.847ValMet: 1.847 ± 0.055	2.523ValAsn: 2.523 ± 0.062	3.721ValPro: 3.721 ± 0.084	2.037ValGln: 2.037 ± 0.057	4.229ValArg: 4.229 ± 0.084	5.159ValSer: 5.159 ± 0.078	4.785ValThr: 4.785 ± 0.105	5.057ValVal: 5.057 ± 0.105	0.806ValTrp: 0.806 ± 0.038	1.735ValTyr: 1.735 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.979TrpAla: 0.979 ± 0.039	0.177TrpCys: 0.177 ± 0.016	0.64TrpAsp: 0.64 ± 0.033	0.704TrpGlu: 0.704 ± 0.036	0.526TrpPhe: 0.526 ± 0.029	0.878TrpGly: 0.878 ± 0.039	0.252TrpHis: 0.252 ± 0.021	0.829TrpIle: 0.829 ± 0.038	0.79TrpLys: 0.79 ± 0.034	1.452TrpLeu: 1.452 ± 0.05	0.356TrpMet: 0.356 ± 0.023	0.545TrpAsn: 0.545 ± 0.03	0.409TrpPro: 0.409 ± 0.027	0.48TrpGln: 0.48 ± 0.026	0.708TrpArg: 0.708 ± 0.032	0.64TrpSer: 0.64 ± 0.025	0.683TrpThr: 0.683 ± 0.034	0.953TrpVal: 0.953 ± 0.043	0.187TrpTrp: 0.187 ± 0.017	0.378TrpTyr: 0.378 ± 0.029	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.522TyrAla: 2.522 ± 0.069	0.343TyrCys: 0.343 ± 0.024	1.425TyrAsp: 1.425 ± 0.051	1.531TyrGlu: 1.531 ± 0.048	1.16TyrPhe: 1.16 ± 0.044	2.213TyrGly: 2.213 ± 0.057	0.487TyrHis: 0.487 ± 0.026	1.255TyrIle: 1.255 ± 0.038	0.987TyrLys: 0.987 ± 0.041	2.522TyrLeu: 2.522 ± 0.062	0.544TyrMet: 0.544 ± 0.028	0.686TyrAsn: 0.686 ± 0.037	1.305TyrPro: 1.305 ± 0.044	0.97TyrGln: 0.97 ± 0.037	1.9TyrArg: 1.9 ± 0.048	1.608TyrSer: 1.608 ± 0.052	1.402TyrThr: 1.402 ± 0.047	1.663TyrVal: 1.663 ± 0.055	0.412TyrTrp: 0.412 ± 0.025	0.715TyrTyr: 0.715 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2198 proteins (705911 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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