Amino acid dipepetide frequency for Peromyscus papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.343AlaAla: 5.343 ± 0.728
1.644AlaCys: 1.644 ± 1.072
2.466AlaAsp: 2.466 ± 0.87
3.699AlaGlu: 3.699 ± 1.409
3.699AlaPhe: 3.699 ± 0.818
6.165AlaGly: 6.165 ± 1.711
0.822AlaHis: 0.822 ± 0.447
2.055AlaIle: 2.055 ± 0.379
3.288AlaLys: 3.288 ± 1.204
3.699AlaLeu: 3.699 ± 1.179
1.233AlaMet: 1.233 ± 0.635
2.055AlaAsn: 2.055 ± 0.747
4.932AlaPro: 4.932 ± 1.553
1.644AlaGln: 1.644 ± 0.551
2.877AlaArg: 2.877 ± 0.57
4.521AlaSer: 4.521 ± 0.918
3.699AlaThr: 3.699 ± 1.339
3.288AlaVal: 3.288 ± 1.092
0.822AlaTrp: 0.822 ± 0.615
0.822AlaTyr: 0.822 ± 0.615
0.0AlaXaa: 0.0 ± 0.0
Cys
2.055CysAla: 2.055 ± 1.097
1.233CysCys: 1.233 ± 0.934
1.233CysAsp: 1.233 ± 1.112
0.0CysGlu: 0.0 ± 0.0
1.233CysPhe: 1.233 ± 0.694
1.233CysGly: 1.233 ± 0.559
0.0CysHis: 0.0 ± 0.0
1.233CysIle: 1.233 ± 0.66
2.466CysLys: 2.466 ± 0.487
0.0CysLeu: 0.0 ± 0.0
2.055CysMet: 2.055 ± 1.095
0.411CysAsn: 0.411 ± 0.308
2.055CysPro: 2.055 ± 0.825
0.411CysGln: 0.411 ± 0.308
2.055CysArg: 2.055 ± 1.095
1.644CysSer: 1.644 ± 1.23
1.644CysThr: 1.644 ± 0.784
0.411CysVal: 0.411 ± 0.572
0.0CysTrp: 0.0 ± 0.0
0.822CysTyr: 0.822 ± 0.76
0.0CysXaa: 0.0 ± 0.0
Asp
2.877AspAla: 2.877 ± 0.648
1.233AspCys: 1.233 ± 0.606
1.644AspAsp: 1.644 ± 0.551
4.521AspGlu: 4.521 ± 1.061
1.644AspPhe: 1.644 ± 0.57
6.576AspGly: 6.576 ± 1.303
0.411AspHis: 0.411 ± 0.379
2.466AspIle: 2.466 ± 1.218
1.233AspLys: 1.233 ± 0.364
4.521AspLeu: 4.521 ± 1.247
1.233AspMet: 1.233 ± 0.694
2.877AspAsn: 2.877 ± 1.076
4.932AspPro: 4.932 ± 1.142
1.644AspGln: 1.644 ± 0.775
2.877AspArg: 2.877 ± 0.895
3.699AspSer: 3.699 ± 0.83
5.754AspThr: 5.754 ± 1.186
3.288AspVal: 3.288 ± 0.994
1.233AspTrp: 1.233 ± 0.582
2.877AspTyr: 2.877 ± 0.96
0.0AspXaa: 0.0 ± 0.0
Glu
3.699GluAla: 3.699 ± 1.406
0.411GluCys: 0.411 ± 0.308
6.165GluAsp: 6.165 ± 1.24
9.864GluGlu: 9.864 ± 3.874
1.644GluPhe: 1.644 ± 0.895
4.932GluGly: 4.932 ± 1.592
0.822GluHis: 0.822 ± 0.535
2.466GluIle: 2.466 ± 0.862
2.877GluLys: 2.877 ± 1.229
2.466GluLeu: 2.466 ± 0.428
1.233GluMet: 1.233 ± 0.763
2.055GluAsn: 2.055 ± 1.217
2.055GluPro: 2.055 ± 1.011
2.877GluGln: 2.877 ± 1.018
2.877GluArg: 2.877 ± 0.979
6.165GluSer: 6.165 ± 1.685
4.11GluThr: 4.11 ± 1.54
4.11GluVal: 4.11 ± 0.397
0.411GluTrp: 0.411 ± 0.308
1.644GluTyr: 1.644 ± 0.517
0.0GluXaa: 0.0 ± 0.0
Phe
2.466PheAla: 2.466 ± 0.923
1.233PheCys: 1.233 ± 0.62
2.055PheAsp: 2.055 ± 0.336
1.644PheGlu: 1.644 ± 0.904
2.055PhePhe: 2.055 ± 0.764
1.233PheGly: 1.233 ± 0.648
1.644PheHis: 1.644 ± 0.728
2.466PheIle: 2.466 ± 0.461
2.877PheLys: 2.877 ± 1.094
2.877PheLeu: 2.877 ± 0.848
0.822PheMet: 0.822 ± 0.536
1.644PheAsn: 1.644 ± 0.661
0.411PhePro: 0.411 ± 0.339
2.466PheGln: 2.466 ± 0.719
2.055PheArg: 2.055 ± 0.455
2.055PheSer: 2.055 ± 0.723
1.644PheThr: 1.644 ± 0.641
1.233PheVal: 1.233 ± 1.145
1.233PheTrp: 1.233 ± 0.721
1.233PheTyr: 1.233 ± 0.373
0.0PheXaa: 0.0 ± 0.0
Gly
2.877GlyAla: 2.877 ± 1.031
2.466GlyCys: 2.466 ± 0.536
3.699GlyAsp: 3.699 ± 0.803
6.576GlyGlu: 6.576 ± 1.514
1.644GlyPhe: 1.644 ± 0.517
9.453GlyGly: 9.453 ± 4.458
2.055GlyHis: 2.055 ± 0.485
5.754GlyIle: 5.754 ± 0.913
1.644GlyLys: 1.644 ± 0.857
5.343GlyLeu: 5.343 ± 1.693
0.822GlyMet: 0.822 ± 0.412
4.521GlyAsn: 4.521 ± 1.208
7.809GlyPro: 7.809 ± 2.581
6.576GlyGln: 6.576 ± 1.262
5.343GlyArg: 5.343 ± 0.957
6.987GlySer: 6.987 ± 2.357
4.11GlyThr: 4.11 ± 0.756
7.398GlyVal: 7.398 ± 1.138
0.411GlyTrp: 0.411 ± 0.339
0.822GlyTyr: 0.822 ± 0.447
0.0GlyXaa: 0.0 ± 0.0
His
2.055HisAla: 2.055 ± 0.7
0.822HisCys: 0.822 ± 0.536
0.822HisAsp: 0.822 ± 0.409
0.411HisGlu: 0.411 ± 0.443
1.644HisPhe: 1.644 ± 0.478
2.877HisGly: 2.877 ± 0.858
1.233HisHis: 1.233 ± 0.573
1.644HisIle: 1.644 ± 1.018
0.411HisLys: 0.411 ± 0.379
2.466HisLeu: 2.466 ± 0.818
0.0HisMet: 0.0 ± 0.0
0.822HisAsn: 0.822 ± 0.402
1.233HisPro: 1.233 ± 0.696
0.411HisGln: 0.411 ± 0.382
0.411HisArg: 0.411 ± 0.379
0.822HisSer: 0.822 ± 0.441
0.822HisThr: 0.822 ± 0.409
2.877HisVal: 2.877 ± 0.648
1.233HisTrp: 1.233 ± 0.377
0.822HisTyr: 0.822 ± 0.364
0.0HisXaa: 0.0 ± 0.0
Ile
3.699IleAla: 3.699 ± 0.997
0.822IleCys: 0.822 ± 0.402
2.466IleAsp: 2.466 ± 0.661
3.288IleGlu: 3.288 ± 0.947
1.644IlePhe: 1.644 ± 0.517
3.699IleGly: 3.699 ± 1.555
2.055IleHis: 2.055 ± 0.85
0.822IleIle: 0.822 ± 0.514
0.0IleLys: 0.0 ± 0.0
5.343IleLeu: 5.343 ± 1.036
0.411IleMet: 0.411 ± 0.308
1.233IleAsn: 1.233 ± 0.696
2.466IlePro: 2.466 ± 0.702
2.055IleGln: 2.055 ± 1.149
2.466IleArg: 2.466 ± 0.776
4.932IleSer: 4.932 ± 1.577
2.466IleThr: 2.466 ± 0.442
2.055IleVal: 2.055 ± 1.11
0.411IleTrp: 0.411 ± 0.443
2.055IleTyr: 2.055 ± 1.077
0.0IleXaa: 0.0 ± 0.0
Lys
2.055LysAla: 2.055 ± 0.698
2.055LysCys: 2.055 ± 0.809
2.055LysAsp: 2.055 ± 1.104
2.466LysGlu: 2.466 ± 1.021
1.644LysPhe: 1.644 ± 0.91
2.877LysGly: 2.877 ± 1.142
0.411LysHis: 0.411 ± 0.308
0.822LysIle: 0.822 ± 0.409
1.233LysLys: 1.233 ± 0.377
2.466LysLeu: 2.466 ± 0.889
0.0LysMet: 0.0 ± 0.0
0.822LysAsn: 0.822 ± 0.441
0.822LysPro: 0.822 ± 0.536
1.644LysGln: 1.644 ± 0.661
6.987LysArg: 6.987 ± 1.236
2.877LysSer: 2.877 ± 1.337
2.466LysThr: 2.466 ± 0.514
3.288LysVal: 3.288 ± 0.774
1.233LysTrp: 1.233 ± 0.62
2.055LysTyr: 2.055 ± 1.013
0.0LysXaa: 0.0 ± 0.0
Leu
2.877LeuAla: 2.877 ± 1.09
1.644LeuCys: 1.644 ± 0.525
4.932LeuAsp: 4.932 ± 0.815
5.343LeuGlu: 5.343 ± 1.371
2.466LeuPhe: 2.466 ± 1.829
8.631LeuGly: 8.631 ± 1.897
3.699LeuHis: 3.699 ± 0.881
2.055LeuIle: 2.055 ± 0.735
2.466LeuLys: 2.466 ± 1.319
6.165LeuLeu: 6.165 ± 2.193
1.644LeuMet: 1.644 ± 0.857
1.644LeuAsn: 1.644 ± 0.168
4.11LeuPro: 4.11 ± 1.219
4.11LeuGln: 4.11 ± 1.37
3.288LeuArg: 3.288 ± 0.898
9.042LeuSer: 9.042 ± 1.225
2.877LeuThr: 2.877 ± 1.213
2.877LeuVal: 2.877 ± 0.936
0.822LeuTrp: 0.822 ± 0.412
2.877LeuTyr: 2.877 ± 1.087
0.0LeuXaa: 0.0 ± 0.0
Met
1.233MetAla: 1.233 ± 0.373
0.822MetCys: 0.822 ± 0.758
0.822MetAsp: 0.822 ± 0.536
0.411MetGlu: 0.411 ± 0.379
0.411MetPhe: 0.411 ± 0.379
0.822MetGly: 0.822 ± 0.409
0.411MetHis: 0.411 ± 0.379
0.822MetIle: 0.822 ± 0.704
0.822MetLys: 0.822 ± 0.536
2.055MetLeu: 2.055 ± 0.81
0.411MetMet: 0.411 ± 0.308
0.411MetAsn: 0.411 ± 0.308
0.411MetPro: 0.411 ± 0.308
2.055MetGln: 2.055 ± 0.747
1.644MetArg: 1.644 ± 0.706
2.055MetSer: 2.055 ± 0.809
0.411MetThr: 0.411 ± 0.382
2.466MetVal: 2.466 ± 1.212
0.0MetTrp: 0.0 ± 0.0
0.822MetTyr: 0.822 ± 0.758
0.0MetXaa: 0.0 ± 0.0
Asn
3.288AsnAla: 3.288 ± 1.734
0.411AsnCys: 0.411 ± 0.308
1.644AsnAsp: 1.644 ± 0.857
1.233AsnGlu: 1.233 ± 0.923
0.822AsnPhe: 0.822 ± 0.763
1.233AsnGly: 1.233 ± 0.655
0.0AsnHis: 0.0 ± 0.0
0.411AsnIle: 0.411 ± 0.339
3.699AsnLys: 3.699 ± 1.196
1.644AsnLeu: 1.644 ± 0.661
0.411AsnMet: 0.411 ± 0.382
2.466AsnAsn: 2.466 ± 1.206
3.288AsnPro: 3.288 ± 0.556
1.644AsnGln: 1.644 ± 0.625
3.288AsnArg: 3.288 ± 1.323
1.233AsnSer: 1.233 ± 0.606
2.877AsnThr: 2.877 ± 0.639
2.055AsnVal: 2.055 ± 1.518
0.822AsnTrp: 0.822 ± 0.412
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.699ProAla: 3.699 ± 0.479
1.233ProCys: 1.233 ± 0.831
4.932ProAsp: 4.932 ± 1.248
4.932ProGlu: 4.932 ± 1.363
0.822ProPhe: 0.822 ± 0.441
3.699ProGly: 3.699 ± 1.487
1.233ProHis: 1.233 ± 0.694
4.11ProIle: 4.11 ± 0.81
2.055ProLys: 2.055 ± 0.728
4.11ProLeu: 4.11 ± 0.739
0.822ProMet: 0.822 ± 0.615
2.877ProAsn: 2.877 ± 1.391
7.398ProPro: 7.398 ± 1.147
0.822ProGln: 0.822 ± 0.409
9.042ProArg: 9.042 ± 3.445
6.987ProSer: 6.987 ± 2.58
5.754ProThr: 5.754 ± 1.698
4.11ProVal: 4.11 ± 0.477
0.411ProTrp: 0.411 ± 0.379
2.055ProTyr: 2.055 ± 1.263
0.0ProXaa: 0.0 ± 0.0
Gln
2.055GlnAla: 2.055 ± 0.636
0.0GlnCys: 0.0 ± 0.0
2.466GlnAsp: 2.466 ± 1.007
1.644GlnGlu: 1.644 ± 1.047
1.644GlnPhe: 1.644 ± 0.707
4.521GlnGly: 4.521 ± 0.486
2.055GlnHis: 2.055 ± 0.84
2.466GlnIle: 2.466 ± 0.755
0.822GlnLys: 0.822 ± 0.447
3.288GlnLeu: 3.288 ± 0.774
0.822GlnMet: 0.822 ± 0.402
1.233GlnAsn: 1.233 ± 0.721
2.466GlnPro: 2.466 ± 0.478
2.055GlnGln: 2.055 ± 0.658
2.055GlnArg: 2.055 ± 0.98
1.644GlnSer: 1.644 ± 0.641
2.877GlnThr: 2.877 ± 0.979
4.521GlnVal: 4.521 ± 2.036
0.411GlnTrp: 0.411 ± 0.308
2.466GlnTyr: 2.466 ± 0.514
0.0GlnXaa: 0.0 ± 0.0
Arg
4.932ArgAla: 4.932 ± 1.056
1.644ArgCys: 1.644 ± 1.107
3.699ArgAsp: 3.699 ± 1.208
2.877ArgGlu: 2.877 ± 1.142
2.466ArgPhe: 2.466 ± 0.512
7.809ArgGly: 7.809 ± 1.032
2.055ArgHis: 2.055 ± 0.681
2.877ArgIle: 2.877 ± 0.648
4.932ArgLys: 4.932 ± 0.505
6.987ArgLeu: 6.987 ± 1.64
1.233ArgMet: 1.233 ± 0.794
1.233ArgAsn: 1.233 ± 0.527
7.398ArgPro: 7.398 ± 1.713
2.466ArgGln: 2.466 ± 1.021
4.521ArgArg: 4.521 ± 0.892
4.932ArgSer: 4.932 ± 0.876
3.699ArgThr: 3.699 ± 1.283
4.521ArgVal: 4.521 ± 0.883
0.411ArgTrp: 0.411 ± 0.308
2.055ArgTyr: 2.055 ± 0.455
0.0ArgXaa: 0.0 ± 0.0
Ser
5.343SerAla: 5.343 ± 1.081
0.822SerCys: 0.822 ± 0.704
5.343SerAsp: 5.343 ± 0.973
3.288SerGlu: 3.288 ± 0.601
2.466SerPhe: 2.466 ± 0.703
7.809SerGly: 7.809 ± 2.467
0.822SerHis: 0.822 ± 0.615
4.11SerIle: 4.11 ± 1.247
1.644SerLys: 1.644 ± 0.517
6.987SerLeu: 6.987 ± 0.924
2.055SerMet: 2.055 ± 1.239
1.644SerAsn: 1.644 ± 0.93
6.165SerPro: 6.165 ± 1.595
4.521SerGln: 4.521 ± 1.927
6.987SerArg: 6.987 ± 1.868
7.398SerSer: 7.398 ± 1.469
4.932SerThr: 4.932 ± 1.497
7.398SerVal: 7.398 ± 1.792
0.411SerTrp: 0.411 ± 0.308
0.822SerTyr: 0.822 ± 0.364
0.0SerXaa: 0.0 ± 0.0
Thr
2.466ThrAla: 2.466 ± 0.496
1.644ThrCys: 1.644 ± 0.563
3.288ThrAsp: 3.288 ± 1.358
2.877ThrGlu: 2.877 ± 0.613
2.055ThrPhe: 2.055 ± 0.98
4.11ThrGly: 4.11 ± 0.81
0.822ThrHis: 0.822 ± 0.441
3.288ThrIle: 3.288 ± 1.499
2.877ThrLys: 2.877 ± 0.777
4.11ThrLeu: 4.11 ± 1.195
1.233ThrMet: 1.233 ± 0.582
1.644ThrAsn: 1.644 ± 0.551
5.754ThrPro: 5.754 ± 1.095
0.411ThrGln: 0.411 ± 0.379
4.521ThrArg: 4.521 ± 0.711
4.932ThrSer: 4.932 ± 1.547
2.466ThrThr: 2.466 ± 0.818
5.754ThrVal: 5.754 ± 2.176
0.822ThrTrp: 0.822 ± 0.441
4.11ThrTyr: 4.11 ± 0.873
0.0ThrXaa: 0.0 ± 0.0
Val
3.699ValAla: 3.699 ± 0.785
1.644ValCys: 1.644 ± 1.315
5.343ValAsp: 5.343 ± 1.202
4.932ValGlu: 4.932 ± 1.125
3.699ValPhe: 3.699 ± 1.022
4.932ValGly: 4.932 ± 1.448
2.466ValHis: 2.466 ± 0.832
3.699ValIle: 3.699 ± 1.475
2.055ValLys: 2.055 ± 1.077
3.699ValLeu: 3.699 ± 0.447
1.644ValMet: 1.644 ± 0.789
0.0ValAsn: 0.0 ± 0.0
4.932ValPro: 4.932 ± 0.472
2.055ValGln: 2.055 ± 0.681
4.521ValArg: 4.521 ± 1.548
6.576ValSer: 6.576 ± 2.134
5.343ValThr: 5.343 ± 1.392
5.343ValVal: 5.343 ± 0.47
1.233ValTrp: 1.233 ± 0.377
2.466ValTyr: 2.466 ± 0.632
0.0ValXaa: 0.0 ± 0.0
Trp
0.411TrpAla: 0.411 ± 0.308
0.0TrpCys: 0.0 ± 0.0
0.411TrpAsp: 0.411 ± 0.308
0.411TrpGlu: 0.411 ± 0.379
0.411TrpPhe: 0.411 ± 0.308
0.822TrpGly: 0.822 ± 0.447
0.411TrpHis: 0.411 ± 0.339
0.411TrpIle: 0.411 ± 0.308
0.822TrpLys: 0.822 ± 0.615
2.055TrpLeu: 2.055 ± 0.681
0.411TrpMet: 0.411 ± 0.308
2.055TrpAsn: 2.055 ± 1.413
0.0TrpPro: 0.0 ± 0.0
0.411TrpGln: 0.411 ± 0.379
2.055TrpArg: 2.055 ± 1.095
0.411TrpSer: 0.411 ± 0.379
0.411TrpThr: 0.411 ± 0.379
1.233TrpVal: 1.233 ± 0.66
0.0TrpTrp: 0.0 ± 0.0
0.411TrpTyr: 0.411 ± 0.308
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.644TyrAla: 1.644 ± 0.742
0.411TyrCys: 0.411 ± 0.572
2.055TyrAsp: 2.055 ± 0.728
2.466TyrGlu: 2.466 ± 0.729
1.233TyrPhe: 1.233 ± 0.373
2.877TyrGly: 2.877 ± 1.004
0.411TyrHis: 0.411 ± 0.382
0.411TyrIle: 0.411 ± 0.339
2.055TyrLys: 2.055 ± 1.159
3.288TyrLeu: 3.288 ± 1.157
0.411TyrMet: 0.411 ± 0.379
0.822TyrAsn: 0.822 ± 0.364
2.466TyrPro: 2.466 ± 0.722
1.233TyrGln: 1.233 ± 0.606
3.288TyrArg: 3.288 ± 1.382
2.055TyrSer: 2.055 ± 0.969
0.822TyrThr: 0.822 ± 0.678
2.055TyrVal: 2.055 ± 0.747
1.233TyrTrp: 1.233 ± 0.377
2.466TyrTyr: 2.466 ± 0.937
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2434 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski