Amino acid dipepetide frequency for Lymantria dispar cypovirus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.407AlaAla: 3.407 ± 0.623
1.136AlaCys: 1.136 ± 0.549
3.407AlaAsp: 3.407 ± 0.587
4.165AlaGlu: 4.165 ± 0.742
2.398AlaPhe: 2.398 ± 0.378
3.029AlaGly: 3.029 ± 0.684
2.019AlaHis: 2.019 ± 0.382
5.427AlaIle: 5.427 ± 0.626
3.155AlaLys: 3.155 ± 0.529
5.931AlaLeu: 5.931 ± 0.888
1.893AlaMet: 1.893 ± 0.411
4.291AlaAsn: 4.291 ± 0.657
2.272AlaPro: 2.272 ± 0.463
1.514AlaGln: 1.514 ± 0.378
4.038AlaArg: 4.038 ± 0.864
4.922AlaSer: 4.922 ± 0.733
3.786AlaThr: 3.786 ± 0.695
5.427AlaVal: 5.427 ± 1.06
0.379AlaTrp: 0.379 ± 0.174
3.029AlaTyr: 3.029 ± 0.551
0.0AlaXaa: 0.0 ± 0.0
Cys
0.252CysAla: 0.252 ± 0.171
0.379CysCys: 0.379 ± 0.325
0.757CysAsp: 0.757 ± 0.349
0.631CysGlu: 0.631 ± 0.285
0.757CysPhe: 0.757 ± 0.17
1.262CysGly: 1.262 ± 0.506
0.126CysHis: 0.126 ± 0.138
0.757CysIle: 0.757 ± 0.343
0.631CysLys: 0.631 ± 0.255
0.757CysLeu: 0.757 ± 0.334
0.252CysMet: 0.252 ± 0.18
0.505CysAsn: 0.505 ± 0.212
0.379CysPro: 0.379 ± 0.222
0.757CysGln: 0.757 ± 0.237
0.757CysArg: 0.757 ± 0.281
0.883CysSer: 0.883 ± 0.601
0.631CysThr: 0.631 ± 0.273
0.757CysVal: 0.757 ± 0.31
0.126CysTrp: 0.126 ± 0.11
0.505CysTyr: 0.505 ± 0.285
0.0CysXaa: 0.0 ± 0.0
Asp
3.912AspAla: 3.912 ± 0.503
0.631AspCys: 0.631 ± 0.412
4.165AspAsp: 4.165 ± 0.943
3.786AspGlu: 3.786 ± 0.496
2.398AspPhe: 2.398 ± 0.6
4.038AspGly: 4.038 ± 0.499
1.767AspHis: 1.767 ± 0.514
4.291AspIle: 4.291 ± 0.622
2.398AspLys: 2.398 ± 0.636
5.553AspLeu: 5.553 ± 0.614
2.398AspMet: 2.398 ± 0.488
2.272AspAsn: 2.272 ± 0.599
1.767AspPro: 1.767 ± 0.507
1.893AspGln: 1.893 ± 0.465
4.291AspArg: 4.291 ± 0.73
3.407AspSer: 3.407 ± 0.572
2.776AspThr: 2.776 ± 0.421
5.174AspVal: 5.174 ± 0.768
0.883AspTrp: 0.883 ± 0.388
2.398AspTyr: 2.398 ± 0.474
0.0AspXaa: 0.0 ± 0.0
Glu
2.903GluAla: 2.903 ± 0.596
0.505GluCys: 0.505 ± 0.246
2.272GluAsp: 2.272 ± 0.711
2.65GluGlu: 2.65 ± 0.644
1.893GluPhe: 1.893 ± 0.495
3.029GluGly: 3.029 ± 0.426
1.01GluHis: 1.01 ± 0.329
4.291GluIle: 4.291 ± 0.685
1.893GluLys: 1.893 ± 0.404
7.572GluLeu: 7.572 ± 1.083
2.398GluMet: 2.398 ± 0.65
3.029GluAsn: 3.029 ± 0.429
2.019GluPro: 2.019 ± 0.58
3.029GluGln: 3.029 ± 0.59
4.038GluArg: 4.038 ± 0.57
3.66GluSer: 3.66 ± 0.638
3.66GluThr: 3.66 ± 0.589
3.66GluVal: 3.66 ± 0.547
0.126GluTrp: 0.126 ± 0.108
3.534GluTyr: 3.534 ± 0.941
0.0GluXaa: 0.0 ± 0.0
Phe
2.903PheAla: 2.903 ± 0.989
0.252PheCys: 0.252 ± 0.15
2.903PheAsp: 2.903 ± 0.759
2.145PheGlu: 2.145 ± 0.654
1.262PhePhe: 1.262 ± 0.245
2.524PheGly: 2.524 ± 0.516
0.631PheHis: 0.631 ± 0.205
2.398PheIle: 2.398 ± 0.455
2.272PheLys: 2.272 ± 0.472
3.155PheLeu: 3.155 ± 0.702
2.019PheMet: 2.019 ± 0.47
2.903PheAsn: 2.903 ± 0.498
1.514PhePro: 1.514 ± 0.295
2.019PheGln: 2.019 ± 0.55
2.145PheArg: 2.145 ± 0.482
2.272PheSer: 2.272 ± 0.596
1.893PheThr: 1.893 ± 0.523
2.776PheVal: 2.776 ± 0.53
0.252PheTrp: 0.252 ± 0.166
0.757PheTyr: 0.757 ± 0.281
0.0PheXaa: 0.0 ± 0.0
Gly
3.029GlyAla: 3.029 ± 0.608
0.379GlyCys: 0.379 ± 0.189
3.155GlyAsp: 3.155 ± 0.452
2.398GlyGlu: 2.398 ± 0.61
2.019GlyPhe: 2.019 ± 0.524
2.65GlyGly: 2.65 ± 0.427
1.136GlyHis: 1.136 ± 0.431
3.281GlyIle: 3.281 ± 0.478
1.641GlyLys: 1.641 ± 0.578
4.291GlyLeu: 4.291 ± 0.842
1.262GlyMet: 1.262 ± 0.383
2.145GlyAsn: 2.145 ± 0.715
1.767GlyPro: 1.767 ± 0.404
2.019GlyGln: 2.019 ± 0.478
2.776GlyArg: 2.776 ± 0.612
3.912GlySer: 3.912 ± 0.572
2.903GlyThr: 2.903 ± 0.462
4.291GlyVal: 4.291 ± 0.828
0.631GlyTrp: 0.631 ± 0.27
2.272GlyTyr: 2.272 ± 0.47
0.0GlyXaa: 0.0 ± 0.0
His
1.262HisAla: 1.262 ± 0.402
0.252HisCys: 0.252 ± 0.15
1.893HisAsp: 1.893 ± 0.419
1.01HisGlu: 1.01 ± 0.27
0.757HisPhe: 0.757 ± 0.313
1.01HisGly: 1.01 ± 0.266
0.883HisHis: 0.883 ± 0.274
1.01HisIle: 1.01 ± 0.49
1.262HisLys: 1.262 ± 0.327
1.893HisLeu: 1.893 ± 0.383
1.262HisMet: 1.262 ± 0.343
0.505HisAsn: 0.505 ± 0.334
0.505HisPro: 0.505 ± 0.353
0.252HisGln: 0.252 ± 0.163
1.767HisArg: 1.767 ± 0.725
1.388HisSer: 1.388 ± 0.282
1.767HisThr: 1.767 ± 0.534
2.65HisVal: 2.65 ± 0.617
0.379HisTrp: 0.379 ± 0.188
0.883HisTyr: 0.883 ± 0.376
0.0HisXaa: 0.0 ± 0.0
Ile
4.417IleAla: 4.417 ± 0.565
0.883IleCys: 0.883 ± 0.341
4.922IleAsp: 4.922 ± 0.752
3.281IleGlu: 3.281 ± 0.511
2.524IlePhe: 2.524 ± 0.43
2.776IleGly: 2.776 ± 0.634
0.631IleHis: 0.631 ± 0.262
3.155IleIle: 3.155 ± 0.784
4.038IleLys: 4.038 ± 0.714
6.941IleLeu: 6.941 ± 0.87
2.903IleMet: 2.903 ± 0.452
4.291IleAsn: 4.291 ± 0.573
3.155IlePro: 3.155 ± 0.606
3.281IleGln: 3.281 ± 0.623
3.281IleArg: 3.281 ± 0.593
4.165IleSer: 4.165 ± 0.724
3.912IleThr: 3.912 ± 0.801
3.786IleVal: 3.786 ± 0.589
0.631IleTrp: 0.631 ± 0.202
2.272IleTyr: 2.272 ± 0.364
0.0IleXaa: 0.0 ± 0.0
Lys
2.65LysAla: 2.65 ± 0.52
0.505LysCys: 0.505 ± 0.267
2.776LysAsp: 2.776 ± 0.564
1.893LysGlu: 1.893 ± 0.42
2.019LysPhe: 2.019 ± 0.298
2.524LysGly: 2.524 ± 0.849
1.514LysHis: 1.514 ± 0.613
2.903LysIle: 2.903 ± 0.666
2.398LysLys: 2.398 ± 0.877
4.291LysLeu: 4.291 ± 0.669
1.388LysMet: 1.388 ± 0.568
1.767LysAsn: 1.767 ± 0.554
0.757LysPro: 0.757 ± 0.404
2.145LysGln: 2.145 ± 0.357
2.903LysArg: 2.903 ± 0.782
2.65LysSer: 2.65 ± 0.454
3.66LysThr: 3.66 ± 1.015
4.038LysVal: 4.038 ± 0.52
0.757LysTrp: 0.757 ± 0.234
3.029LysTyr: 3.029 ± 0.641
0.0LysXaa: 0.0 ± 0.0
Leu
4.669LeuAla: 4.669 ± 0.695
1.262LeuCys: 1.262 ± 0.436
5.553LeuAsp: 5.553 ± 0.682
4.417LeuGlu: 4.417 ± 0.546
4.038LeuPhe: 4.038 ± 0.747
3.407LeuGly: 3.407 ± 1.013
1.893LeuHis: 1.893 ± 0.543
4.796LeuIle: 4.796 ± 0.908
4.038LeuLys: 4.038 ± 0.89
9.97LeuLeu: 9.97 ± 1.101
3.155LeuMet: 3.155 ± 0.394
6.815LeuAsn: 6.815 ± 0.875
4.796LeuPro: 4.796 ± 0.838
3.281LeuGln: 3.281 ± 0.76
7.698LeuArg: 7.698 ± 0.974
8.329LeuSer: 8.329 ± 0.632
6.941LeuThr: 6.941 ± 0.671
4.165LeuVal: 4.165 ± 0.663
0.505LeuTrp: 0.505 ± 0.269
3.029LeuTyr: 3.029 ± 0.611
0.0LeuXaa: 0.0 ± 0.0
Met
3.281MetAla: 3.281 ± 0.36
0.252MetCys: 0.252 ± 0.192
2.019MetAsp: 2.019 ± 0.327
1.514MetGlu: 1.514 ± 0.426
0.757MetPhe: 0.757 ± 0.282
1.388MetGly: 1.388 ± 0.446
0.757MetHis: 0.757 ± 0.302
1.514MetIle: 1.514 ± 0.377
1.641MetLys: 1.641 ± 0.498
2.776MetLeu: 2.776 ± 0.828
1.388MetMet: 1.388 ± 0.221
2.272MetAsn: 2.272 ± 0.745
1.767MetPro: 1.767 ± 0.734
1.641MetGln: 1.641 ± 0.415
2.524MetArg: 2.524 ± 0.522
2.398MetSer: 2.398 ± 0.506
2.272MetThr: 2.272 ± 0.627
1.641MetVal: 1.641 ± 0.514
0.0MetTrp: 0.0 ± 0.0
1.514MetTyr: 1.514 ± 0.454
0.0MetXaa: 0.0 ± 0.0
Asn
5.427AsnAla: 5.427 ± 0.465
0.757AsnCys: 0.757 ± 0.23
3.786AsnAsp: 3.786 ± 1.065
5.174AsnGlu: 5.174 ± 0.872
2.903AsnPhe: 2.903 ± 0.561
3.155AsnGly: 3.155 ± 0.509
0.631AsnHis: 0.631 ± 0.427
4.291AsnIle: 4.291 ± 0.991
2.524AsnLys: 2.524 ± 0.628
3.786AsnLeu: 3.786 ± 0.57
1.388AsnMet: 1.388 ± 0.315
2.903AsnAsn: 2.903 ± 0.653
2.019AsnPro: 2.019 ± 0.623
2.272AsnGln: 2.272 ± 0.597
2.65AsnArg: 2.65 ± 0.847
4.669AsnSer: 4.669 ± 0.586
4.669AsnThr: 4.669 ± 0.998
4.796AsnVal: 4.796 ± 0.88
0.126AsnTrp: 0.126 ± 0.106
2.65AsnTyr: 2.65 ± 0.534
0.0AsnXaa: 0.0 ± 0.0
Pro
2.776ProAla: 2.776 ± 0.414
0.631ProCys: 0.631 ± 0.207
1.893ProAsp: 1.893 ± 0.603
2.272ProGlu: 2.272 ± 0.454
1.767ProPhe: 1.767 ± 0.677
1.388ProGly: 1.388 ± 0.425
0.631ProHis: 0.631 ± 0.255
3.155ProIle: 3.155 ± 0.517
1.641ProLys: 1.641 ± 0.553
3.407ProLeu: 3.407 ± 0.586
1.262ProMet: 1.262 ± 0.387
2.65ProAsn: 2.65 ± 0.723
1.767ProPro: 1.767 ± 0.542
1.01ProGln: 1.01 ± 0.371
2.272ProArg: 2.272 ± 0.458
2.65ProSer: 2.65 ± 0.541
2.65ProThr: 2.65 ± 0.513
2.65ProVal: 2.65 ± 0.788
0.505ProTrp: 0.505 ± 0.179
1.388ProTyr: 1.388 ± 0.307
0.0ProXaa: 0.0 ± 0.0
Gln
1.893GlnAla: 1.893 ± 0.652
0.379GlnCys: 0.379 ± 0.182
2.398GlnAsp: 2.398 ± 0.679
2.019GlnGlu: 2.019 ± 0.415
1.514GlnPhe: 1.514 ± 0.518
1.01GlnGly: 1.01 ± 0.32
1.641GlnHis: 1.641 ± 0.493
2.272GlnIle: 2.272 ± 0.555
2.145GlnLys: 2.145 ± 0.424
3.912GlnLeu: 3.912 ± 0.537
0.883GlnMet: 0.883 ± 0.355
2.398GlnAsn: 2.398 ± 0.498
1.893GlnPro: 1.893 ± 0.369
1.641GlnGln: 1.641 ± 0.397
2.272GlnArg: 2.272 ± 0.335
3.912GlnSer: 3.912 ± 0.655
2.398GlnThr: 2.398 ± 0.53
2.019GlnVal: 2.019 ± 0.399
0.126GlnTrp: 0.126 ± 0.116
2.776GlnTyr: 2.776 ± 0.606
0.0GlnXaa: 0.0 ± 0.0
Arg
4.291ArgAla: 4.291 ± 0.598
0.379ArgCys: 0.379 ± 0.186
3.534ArgAsp: 3.534 ± 0.432
4.165ArgGlu: 4.165 ± 0.719
2.145ArgPhe: 2.145 ± 0.502
2.903ArgGly: 2.903 ± 0.556
1.893ArgHis: 1.893 ± 0.52
5.553ArgIle: 5.553 ± 0.92
2.776ArgLys: 2.776 ± 0.643
6.436ArgLeu: 6.436 ± 0.776
1.641ArgMet: 1.641 ± 0.237
4.291ArgAsn: 4.291 ± 0.694
2.272ArgPro: 2.272 ± 0.392
2.272ArgGln: 2.272 ± 0.662
2.776ArgArg: 2.776 ± 0.528
3.407ArgSer: 3.407 ± 0.73
3.029ArgThr: 3.029 ± 0.731
4.796ArgVal: 4.796 ± 0.589
0.126ArgTrp: 0.126 ± 0.092
2.776ArgTyr: 2.776 ± 0.431
0.0ArgXaa: 0.0 ± 0.0
Ser
5.048SerAla: 5.048 ± 0.717
0.883SerCys: 0.883 ± 0.259
4.922SerAsp: 4.922 ± 0.79
4.291SerGlu: 4.291 ± 0.561
3.155SerPhe: 3.155 ± 0.761
4.417SerGly: 4.417 ± 0.699
1.136SerHis: 1.136 ± 0.282
4.669SerIle: 4.669 ± 0.813
3.786SerLys: 3.786 ± 0.794
4.922SerLeu: 4.922 ± 0.718
2.903SerMet: 2.903 ± 0.604
4.038SerAsn: 4.038 ± 0.552
2.903SerPro: 2.903 ± 0.561
2.903SerGln: 2.903 ± 0.742
4.165SerArg: 4.165 ± 0.544
5.427SerSer: 5.427 ± 0.972
3.534SerThr: 3.534 ± 0.448
5.048SerVal: 5.048 ± 0.666
0.757SerTrp: 0.757 ± 0.23
2.65SerTyr: 2.65 ± 0.668
0.0SerXaa: 0.0 ± 0.0
Thr
4.417ThrAla: 4.417 ± 0.8
0.631ThrCys: 0.631 ± 0.288
3.534ThrAsp: 3.534 ± 0.635
3.029ThrGlu: 3.029 ± 0.696
2.524ThrPhe: 2.524 ± 0.632
2.272ThrGly: 2.272 ± 0.342
1.01ThrHis: 1.01 ± 0.302
4.543ThrIle: 4.543 ± 0.915
3.029ThrLys: 3.029 ± 0.791
7.698ThrLeu: 7.698 ± 1.217
1.641ThrMet: 1.641 ± 0.307
4.417ThrAsn: 4.417 ± 0.503
2.145ThrPro: 2.145 ± 0.287
2.903ThrGln: 2.903 ± 0.423
3.029ThrArg: 3.029 ± 0.498
6.058ThrSer: 6.058 ± 1.131
4.417ThrThr: 4.417 ± 0.656
3.534ThrVal: 3.534 ± 0.605
0.379ThrTrp: 0.379 ± 0.143
3.281ThrTyr: 3.281 ± 0.547
0.0ThrXaa: 0.0 ± 0.0
Val
4.796ValAla: 4.796 ± 1.244
0.757ValCys: 0.757 ± 0.299
3.534ValAsp: 3.534 ± 0.716
4.796ValGlu: 4.796 ± 0.627
2.903ValPhe: 2.903 ± 0.826
3.281ValGly: 3.281 ± 0.53
2.524ValHis: 2.524 ± 0.582
3.786ValIle: 3.786 ± 0.703
2.903ValLys: 2.903 ± 0.774
4.796ValLeu: 4.796 ± 0.583
2.398ValMet: 2.398 ± 0.418
4.922ValAsn: 4.922 ± 0.679
2.524ValPro: 2.524 ± 0.512
3.155ValGln: 3.155 ± 0.508
4.922ValArg: 4.922 ± 0.645
4.165ValSer: 4.165 ± 0.732
5.3ValThr: 5.3 ± 0.791
5.931ValVal: 5.931 ± 1.71
0.883ValTrp: 0.883 ± 0.221
2.398ValTyr: 2.398 ± 0.554
0.0ValXaa: 0.0 ± 0.0
Trp
0.379TrpAla: 0.379 ± 0.18
0.126TrpCys: 0.126 ± 0.108
0.252TrpAsp: 0.252 ± 0.168
0.379TrpGlu: 0.379 ± 0.18
0.252TrpPhe: 0.252 ± 0.177
0.126TrpGly: 0.126 ± 0.106
0.126TrpHis: 0.126 ± 0.116
0.505TrpIle: 0.505 ± 0.169
0.631TrpLys: 0.631 ± 0.203
1.388TrpLeu: 1.388 ± 0.348
0.126TrpMet: 0.126 ± 0.138
0.757TrpAsn: 0.757 ± 0.247
0.126TrpPro: 0.126 ± 0.092
0.379TrpGln: 0.379 ± 0.143
0.505TrpArg: 0.505 ± 0.256
0.883TrpSer: 0.883 ± 0.217
0.252TrpThr: 0.252 ± 0.121
0.126TrpVal: 0.126 ± 0.139
0.126TrpTrp: 0.126 ± 0.143
0.379TrpTyr: 0.379 ± 0.297
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.912TyrAla: 3.912 ± 0.753
0.883TyrCys: 0.883 ± 0.399
2.524TyrAsp: 2.524 ± 0.5
3.155TyrGlu: 3.155 ± 0.451
1.01TyrPhe: 1.01 ± 0.344
1.893TyrGly: 1.893 ± 0.344
0.631TyrHis: 0.631 ± 0.199
2.65TyrIle: 2.65 ± 0.54
1.767TyrLys: 1.767 ± 0.469
3.281TyrLeu: 3.281 ± 0.655
0.631TyrMet: 0.631 ± 0.313
3.407TyrAsn: 3.407 ± 0.542
2.019TyrPro: 2.019 ± 0.438
1.136TyrGln: 1.136 ± 0.423
2.65TyrArg: 2.65 ± 0.606
2.398TyrSer: 2.398 ± 0.385
4.038TyrThr: 4.038 ± 0.733
3.407TyrVal: 3.407 ± 0.921
0.126TyrTrp: 0.126 ± 0.106
1.767TyrTyr: 1.767 ± 0.496
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (7925 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski