Amino acid dipepetide frequency for Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.516AlaAla: 8.516 ± 0.05
1.09AlaCys: 1.09 ± 0.015
4.216AlaAsp: 4.216 ± 0.027
5.167AlaGlu: 5.167 ± 0.035
3.165AlaPhe: 3.165 ± 0.024
5.66AlaGly: 5.66 ± 0.034
1.699AlaHis: 1.699 ± 0.018
4.497AlaIle: 4.497 ± 0.029
4.249AlaLys: 4.249 ± 0.025
7.539AlaLeu: 7.539 ± 0.039
2.038AlaMet: 2.038 ± 0.016
2.958AlaAsn: 2.958 ± 0.02
4.585AlaPro: 4.585 ± 0.039
3.321AlaGln: 3.321 ± 0.023
4.614AlaArg: 4.614 ± 0.03
6.879AlaSer: 6.879 ± 0.034
5.22AlaThr: 5.22 ± 0.033
5.343AlaVal: 5.343 ± 0.029
1.219AlaTrp: 1.219 ± 0.012
2.185AlaTyr: 2.185 ± 0.019
0.0AlaXaa: 0.0 ± 0.0
Cys
0.923CysAla: 0.923 ± 0.014
0.246CysCys: 0.246 ± 0.007
0.693CysAsp: 0.693 ± 0.012
0.635CysGlu: 0.635 ± 0.012
0.561CysPhe: 0.561 ± 0.009
0.95CysGly: 0.95 ± 0.014
0.35CysHis: 0.35 ± 0.007
0.743CysIle: 0.743 ± 0.01
0.586CysLys: 0.586 ± 0.012
1.252CysLeu: 1.252 ± 0.014
0.292CysMet: 0.292 ± 0.006
0.478CysAsn: 0.478 ± 0.008
0.658CysPro: 0.658 ± 0.011
0.49CysGln: 0.49 ± 0.008
0.772CysArg: 0.772 ± 0.012
0.93CysSer: 0.93 ± 0.012
0.73CysThr: 0.73 ± 0.01
0.809CysVal: 0.809 ± 0.013
0.231CysTrp: 0.231 ± 0.006
0.407CysTyr: 0.407 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
4.723AspAla: 4.723 ± 0.027
0.675AspCys: 0.675 ± 0.011
4.393AspAsp: 4.393 ± 0.035
4.612AspGlu: 4.612 ± 0.032
2.315AspPhe: 2.315 ± 0.019
4.212AspGly: 4.212 ± 0.028
1.285AspHis: 1.285 ± 0.015
3.279AspIle: 3.279 ± 0.023
2.791AspLys: 2.791 ± 0.023
5.102AspLeu: 5.102 ± 0.032
1.382AspMet: 1.382 ± 0.015
2.044AspAsn: 2.044 ± 0.018
3.282AspPro: 3.282 ± 0.024
1.987AspGln: 1.987 ± 0.018
2.997AspArg: 2.997 ± 0.026
4.103AspSer: 4.103 ± 0.031
3.033AspThr: 3.033 ± 0.024
3.723AspVal: 3.723 ± 0.023
0.965AspTrp: 0.965 ± 0.012
1.701AspTyr: 1.701 ± 0.017
0.0AspXaa: 0.0 ± 0.0
Glu
5.603GluAla: 5.603 ± 0.041
0.638GluCys: 0.638 ± 0.01
4.287GluAsp: 4.287 ± 0.033
5.349GluGlu: 5.349 ± 0.047
2.021GluPhe: 2.021 ± 0.017
3.735GluGly: 3.735 ± 0.025
1.416GluHis: 1.416 ± 0.016
3.11GluIle: 3.11 ± 0.023
3.778GluLys: 3.778 ± 0.027
5.249GluLeu: 5.249 ± 0.034
1.477GluMet: 1.477 ± 0.016
2.362GluAsn: 2.362 ± 0.018
2.972GluPro: 2.972 ± 0.035
2.445GluGln: 2.445 ± 0.02
3.739GluArg: 3.739 ± 0.027
4.298GluSer: 4.298 ± 0.03
3.75GluThr: 3.75 ± 0.031
3.694GluVal: 3.694 ± 0.025
0.936GluTrp: 0.936 ± 0.013
1.703GluTyr: 1.703 ± 0.016
0.0GluXaa: 0.0 ± 0.0
Phe
3.04PheAla: 3.04 ± 0.026
0.595PheCys: 0.595 ± 0.01
2.349PheAsp: 2.349 ± 0.019
2.24PheGlu: 2.24 ± 0.019
1.679PhePhe: 1.679 ± 0.019
2.908PheGly: 2.908 ± 0.026
0.909PheHis: 0.909 ± 0.012
1.975PheIle: 1.975 ± 0.02
1.665PheLys: 1.665 ± 0.015
3.459PheLeu: 3.459 ± 0.023
0.835PheMet: 0.835 ± 0.011
1.547PheAsn: 1.547 ± 0.016
1.911PhePro: 1.911 ± 0.018
1.422PheGln: 1.422 ± 0.015
1.923PheArg: 1.923 ± 0.018
2.962PheSer: 2.962 ± 0.023
2.205PheThr: 2.205 ± 0.019
2.417PheVal: 2.417 ± 0.02
0.685PheTrp: 0.685 ± 0.01
1.138PheTyr: 1.138 ± 0.013
0.0PheXaa: 0.0 ± 0.0
Gly
5.216GlyAla: 5.216 ± 0.033
0.941GlyCys: 0.941 ± 0.013
3.814GlyAsp: 3.814 ± 0.026
3.586GlyGlu: 3.586 ± 0.026
2.927GlyPhe: 2.927 ± 0.02
5.482GlyGly: 5.482 ± 0.05
1.731GlyHis: 1.731 ± 0.017
3.719GlyIle: 3.719 ± 0.025
3.552GlyLys: 3.552 ± 0.028
6.14GlyLeu: 6.14 ± 0.035
1.625GlyMet: 1.625 ± 0.017
2.695GlyAsn: 2.695 ± 0.023
3.255GlyPro: 3.255 ± 0.026
2.625GlyGln: 2.625 ± 0.023
4.008GlyArg: 4.008 ± 0.026
5.682GlySer: 5.682 ± 0.034
4.039GlyThr: 4.039 ± 0.031
4.279GlyVal: 4.279 ± 0.028
1.213GlyTrp: 1.213 ± 0.015
2.202GlyTyr: 2.202 ± 0.019
0.0GlyXaa: 0.0 ± 0.0
His
1.762HisAla: 1.762 ± 0.016
0.335HisCys: 0.335 ± 0.007
1.397HisAsp: 1.397 ± 0.016
1.374HisGlu: 1.374 ± 0.014
0.936HisPhe: 0.936 ± 0.01
1.775HisGly: 1.775 ± 0.02
0.814HisHis: 0.814 ± 0.014
1.253HisIle: 1.253 ± 0.013
1.005HisLys: 1.005 ± 0.013
2.194HisLeu: 2.194 ± 0.02
0.522HisMet: 0.522 ± 0.01
0.85HisAsn: 0.85 ± 0.011
1.545HisPro: 1.545 ± 0.018
0.985HisGln: 0.985 ± 0.013
1.456HisArg: 1.456 ± 0.017
1.705HisSer: 1.705 ± 0.014
1.175HisThr: 1.175 ± 0.013
1.433HisVal: 1.433 ± 0.015
0.367HisTrp: 0.367 ± 0.008
0.72HisTyr: 0.72 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.291IleAla: 4.291 ± 0.029
0.791IleCys: 0.791 ± 0.012
3.073IleAsp: 3.073 ± 0.023
3.08IleGlu: 3.08 ± 0.02
2.059IlePhe: 2.059 ± 0.019
3.399IleGly: 3.399 ± 0.028
1.226IleHis: 1.226 ± 0.013
2.748IleIle: 2.748 ± 0.026
2.448IleLys: 2.448 ± 0.02
4.629IleLeu: 4.629 ± 0.03
1.127IleMet: 1.127 ± 0.013
1.958IleAsn: 1.958 ± 0.016
3.062IlePro: 3.062 ± 0.024
1.967IleGln: 1.967 ± 0.017
2.842IleArg: 2.842 ± 0.022
3.934IleSer: 3.934 ± 0.02
3.005IleThr: 3.005 ± 0.024
3.308IleVal: 3.308 ± 0.024
0.805IleTrp: 0.805 ± 0.013
1.459IleTyr: 1.459 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.474LysAla: 4.474 ± 0.032
0.549LysCys: 0.549 ± 0.013
3.195LysAsp: 3.195 ± 0.026
3.472LysGlu: 3.472 ± 0.027
1.567LysPhe: 1.567 ± 0.018
3.179LysGly: 3.179 ± 0.025
1.213LysHis: 1.213 ± 0.015
2.402LysIle: 2.402 ± 0.022
3.501LysLys: 3.501 ± 0.037
4.3LysLeu: 4.3 ± 0.03
1.077LysMet: 1.077 ± 0.015
1.948LysAsn: 1.948 ± 0.017
2.895LysPro: 2.895 ± 0.027
1.939LysGln: 1.939 ± 0.017
3.339LysArg: 3.339 ± 0.025
3.616LysSer: 3.616 ± 0.025
3.117LysThr: 3.117 ± 0.023
3.015LysVal: 3.015 ± 0.024
0.78LysTrp: 0.78 ± 0.011
1.477LysTyr: 1.477 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
7.657LeuAla: 7.657 ± 0.037
1.202LeuCys: 1.202 ± 0.014
5.2LeuAsp: 5.2 ± 0.033
5.532LeuGlu: 5.532 ± 0.035
3.311LeuPhe: 3.311 ± 0.026
5.953LeuGly: 5.953 ± 0.033
2.096LeuHis: 2.096 ± 0.019
4.129LeuIle: 4.129 ± 0.03
4.401LeuLys: 4.401 ± 0.031
7.979LeuLeu: 7.979 ± 0.051
1.887LeuMet: 1.887 ± 0.017
3.221LeuAsn: 3.221 ± 0.024
5.193LeuPro: 5.193 ± 0.033
3.703LeuGln: 3.703 ± 0.028
5.49LeuArg: 5.49 ± 0.034
7.034LeuSer: 7.034 ± 0.037
4.784LeuThr: 4.784 ± 0.026
5.407LeuVal: 5.407 ± 0.032
1.263LeuTrp: 1.263 ± 0.015
2.325LeuTyr: 2.325 ± 0.019
0.0LeuXaa: 0.0 ± 0.0
Met
2.374MetAla: 2.374 ± 0.019
0.262MetCys: 0.262 ± 0.006
1.273MetAsp: 1.273 ± 0.014
1.305MetGlu: 1.305 ± 0.014
0.813MetPhe: 0.813 ± 0.012
1.524MetGly: 1.524 ± 0.015
0.491MetHis: 0.491 ± 0.009
1.113MetIle: 1.113 ± 0.014
1.093MetLys: 1.093 ± 0.013
1.885MetLeu: 1.885 ± 0.016
0.642MetMet: 0.642 ± 0.01
0.86MetAsn: 0.86 ± 0.014
1.34MetPro: 1.34 ± 0.015
0.848MetGln: 0.848 ± 0.012
1.241MetArg: 1.241 ± 0.015
2.013MetSer: 2.013 ± 0.019
1.383MetThr: 1.383 ± 0.015
1.381MetVal: 1.381 ± 0.015
0.27MetTrp: 0.27 ± 0.007
0.544MetTyr: 0.544 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
3.064AsnAla: 3.064 ± 0.023
0.48AsnCys: 0.48 ± 0.009
2.12AsnAsp: 2.12 ± 0.02
2.15AsnGlu: 2.15 ± 0.018
1.417AsnPhe: 1.417 ± 0.014
3.064AsnGly: 3.064 ± 0.03
0.871AsnHis: 0.871 ± 0.012
2.161AsnIle: 2.161 ± 0.017
1.814AsnLys: 1.814 ± 0.016
3.329AsnLeu: 3.329 ± 0.023
0.937AsnMet: 0.937 ± 0.014
1.612AsnAsn: 1.612 ± 0.021
2.418AsnPro: 2.418 ± 0.019
1.387AsnGln: 1.387 ± 0.016
1.966AsnArg: 1.966 ± 0.017
2.785AsnSer: 2.785 ± 0.021
2.24AsnThr: 2.24 ± 0.02
2.333AsnVal: 2.333 ± 0.019
0.628AsnTrp: 0.628 ± 0.011
1.102AsnTyr: 1.102 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
4.849ProAla: 4.849 ± 0.04
0.55ProCys: 0.55 ± 0.01
3.305ProAsp: 3.305 ± 0.023
4.035ProGlu: 4.035 ± 0.03
2.041ProPhe: 2.041 ± 0.018
3.916ProGly: 3.916 ± 0.035
1.237ProHis: 1.237 ± 0.014
2.537ProIle: 2.537 ± 0.021
2.8ProLys: 2.8 ± 0.025
4.437ProLeu: 4.437 ± 0.026
1.122ProMet: 1.122 ± 0.015
2.176ProAsn: 2.176 ± 0.02
4.405ProPro: 4.405 ± 0.051
2.43ProGln: 2.43 ± 0.027
3.229ProArg: 3.229 ± 0.025
5.441ProSer: 5.441 ± 0.039
3.743ProThr: 3.743 ± 0.029
3.572ProVal: 3.572 ± 0.027
0.79ProTrp: 0.79 ± 0.011
1.493ProTyr: 1.493 ± 0.019
0.0ProXaa: 0.0 ± 0.0
Gln
3.476GlnAla: 3.476 ± 0.024
0.453GlnCys: 0.453 ± 0.009
2.263GlnAsp: 2.263 ± 0.017
2.484GlnGlu: 2.484 ± 0.02
1.303GlnPhe: 1.303 ± 0.014
2.58GlnGly: 2.58 ± 0.023
1.043GlnHis: 1.043 ± 0.015
1.88GlnIle: 1.88 ± 0.02
2.008GlnLys: 2.008 ± 0.017
3.422GlnLeu: 3.422 ± 0.024
0.901GlnMet: 0.901 ± 0.014
1.57GlnAsn: 1.57 ± 0.019
2.494GlnPro: 2.494 ± 0.027
2.315GlnGln: 2.315 ± 0.037
2.544GlnArg: 2.544 ± 0.02
2.923GlnSer: 2.923 ± 0.02
2.251GlnThr: 2.251 ± 0.018
2.272GlnVal: 2.272 ± 0.018
0.624GlnTrp: 0.624 ± 0.009
1.173GlnTyr: 1.173 ± 0.014
0.0GlnXaa: 0.0 ± 0.0
Arg
4.372ArgAla: 4.372 ± 0.023
0.716ArgCys: 0.716 ± 0.011
3.409ArgAsp: 3.409 ± 0.024
3.62ArgGlu: 3.62 ± 0.028
2.142ArgPhe: 2.142 ± 0.02
3.611ArgGly: 3.611 ± 0.028
1.548ArgHis: 1.548 ± 0.016
2.863ArgIle: 2.863 ± 0.022
3.325ArgLys: 3.325 ± 0.025
5.292ArgLeu: 5.292 ± 0.033
1.306ArgMet: 1.306 ± 0.014
2.251ArgAsn: 2.251 ± 0.019
3.319ArgPro: 3.319 ± 0.027
2.575ArgGln: 2.575 ± 0.023
4.781ArgArg: 4.781 ± 0.04
4.455ArgSer: 4.455 ± 0.034
3.133ArgThr: 3.133 ± 0.024
3.329ArgVal: 3.329 ± 0.027
0.965ArgTrp: 0.965 ± 0.01
1.67ArgTyr: 1.67 ± 0.016
0.0ArgXaa: 0.0 ± 0.0
Ser
6.166SerAla: 6.166 ± 0.033
0.926SerCys: 0.926 ± 0.011
4.292SerAsp: 4.292 ± 0.034
4.191SerGlu: 4.191 ± 0.031
3.012SerPhe: 3.012 ± 0.023
5.434SerGly: 5.434 ± 0.035
1.891SerHis: 1.891 ± 0.019
4.1SerIle: 4.1 ± 0.026
3.835SerLys: 3.835 ± 0.029
6.91SerLeu: 6.91 ± 0.04
1.808SerMet: 1.808 ± 0.017
2.966SerAsn: 2.966 ± 0.026
5.043SerPro: 5.043 ± 0.04
3.26SerGln: 3.26 ± 0.022
4.743SerArg: 4.743 ± 0.032
7.909SerSer: 7.909 ± 0.058
5.196SerThr: 5.196 ± 0.031
4.472SerVal: 4.472 ± 0.028
1.223SerTrp: 1.223 ± 0.014
2.119SerTyr: 2.119 ± 0.018
0.0SerXaa: 0.0 ± 0.0
Thr
5.108ThrAla: 5.108 ± 0.029
0.794ThrCys: 0.794 ± 0.013
2.907ThrAsp: 2.907 ± 0.025
3.305ThrGlu: 3.305 ± 0.026
2.254ThrPhe: 2.254 ± 0.021
4.177ThrGly: 4.177 ± 0.027
1.239ThrHis: 1.239 ± 0.013
3.244ThrIle: 3.244 ± 0.028
2.92ThrLys: 2.92 ± 0.021
5.084ThrLeu: 5.084 ± 0.024
1.2ThrMet: 1.2 ± 0.011
2.19ThrAsn: 2.19 ± 0.019
4.069ThrPro: 4.069 ± 0.038
2.142ThrGln: 2.142 ± 0.017
3.093ThrArg: 3.093 ± 0.024
5.107ThrSer: 5.107 ± 0.041
4.234ThrThr: 4.234 ± 0.05
3.795ThrVal: 3.795 ± 0.03
0.92ThrTrp: 0.92 ± 0.012
1.669ThrTyr: 1.669 ± 0.016
0.0ThrXaa: 0.0 ± 0.0
Val
5.179ValAla: 5.179 ± 0.028
0.835ValCys: 0.835 ± 0.013
3.742ValAsp: 3.742 ± 0.027
3.937ValGlu: 3.937 ± 0.028
2.534ValPhe: 2.534 ± 0.022
3.993ValGly: 3.993 ± 0.025
1.39ValHis: 1.39 ± 0.016
3.172ValIle: 3.172 ± 0.02
3.135ValLys: 3.135 ± 0.022
5.504ValLeu: 5.504 ± 0.028
1.391ValMet: 1.391 ± 0.014
2.3ValAsn: 2.3 ± 0.019
3.521ValPro: 3.521 ± 0.027
2.399ValGln: 2.399 ± 0.02
3.252ValArg: 3.252 ± 0.024
4.59ValSer: 4.59 ± 0.026
3.647ValThr: 3.647 ± 0.03
4.331ValVal: 4.331 ± 0.03
0.894ValTrp: 0.894 ± 0.013
1.793ValTyr: 1.793 ± 0.019
0.0ValXaa: 0.0 ± 0.0
Trp
1.205TrpAla: 1.205 ± 0.014
0.22TrpCys: 0.22 ± 0.006
0.945TrpAsp: 0.945 ± 0.013
0.877TrpGlu: 0.877 ± 0.013
0.591TrpPhe: 0.591 ± 0.009
1.022TrpGly: 1.022 ± 0.011
0.39TrpHis: 0.39 ± 0.007
0.84TrpIle: 0.84 ± 0.013
0.892TrpLys: 0.892 ± 0.013
1.432TrpLeu: 1.432 ± 0.014
0.409TrpMet: 0.409 ± 0.008
0.684TrpAsn: 0.684 ± 0.011
0.674TrpPro: 0.674 ± 0.012
0.626TrpGln: 0.626 ± 0.01
0.992TrpArg: 0.992 ± 0.013
1.112TrpSer: 1.112 ± 0.012
0.962TrpThr: 0.962 ± 0.013
0.946TrpVal: 0.946 ± 0.015
0.303TrpTrp: 0.303 ± 0.007
0.472TrpTyr: 0.472 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.162TyrAla: 2.162 ± 0.018
0.439TyrCys: 0.439 ± 0.009
1.729TyrAsp: 1.729 ± 0.018
1.612TyrGlu: 1.612 ± 0.016
1.215TyrPhe: 1.215 ± 0.014
2.158TyrGly: 2.158 ± 0.021
0.763TyrHis: 0.763 ± 0.012
1.444TyrIle: 1.444 ± 0.015
1.256TyrLys: 1.256 ± 0.014
2.628TyrLeu: 2.628 ± 0.024
0.678TyrMet: 0.678 ± 0.011
1.208TyrAsn: 1.208 ± 0.015
1.471TyrPro: 1.471 ± 0.017
1.111TyrGln: 1.111 ± 0.014
1.662TyrArg: 1.662 ± 0.016
2.019TyrSer: 2.019 ± 0.019
1.604TyrThr: 1.604 ± 0.017
1.678TyrVal: 1.678 ± 0.017
0.514TyrTrp: 0.514 ± 0.009
0.963TyrTyr: 0.963 ± 0.013
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.005XaaXaa: 0.005 ± 0.005
Statistics based on 16646 proteins (6886139 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski