Amino acid dipepetide frequency for Ooceraea biroi (Clonal raider ant) (Cerapachys biroi)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.748AlaAla: 5.748 ± 0.052	1.309AlaCys: 1.309 ± 0.029	3.195AlaAsp: 3.195 ± 0.027	4.156AlaGlu: 4.156 ± 0.037	2.188AlaPhe: 2.188 ± 0.02	3.629AlaGly: 3.629 ± 0.031	1.491AlaHis: 1.491 ± 0.016	3.657AlaIle: 3.657 ± 0.028	3.699AlaLys: 3.699 ± 0.03	5.832AlaLeu: 5.832 ± 0.042	1.619AlaMet: 1.619 ± 0.016	2.879AlaAsn: 2.879 ± 0.024	2.927AlaPro: 2.927 ± 0.027	2.496AlaGln: 2.496 ± 0.026	4.051AlaArg: 4.051 ± 0.029	5.347AlaSer: 5.347 ± 0.037	4.299AlaThr: 4.299 ± 0.033	4.274AlaVal: 4.274 ± 0.029	0.659AlaTrp: 0.659 ± 0.011	1.705AlaTyr: 1.705 ± 0.018	0.001AlaXaa: 0.001 ± 0.0
Cys	1.232CysAla: 1.232 ± 0.018	0.501CysCys: 0.501 ± 0.012	1.176CysAsp: 1.176 ± 0.02	1.188CysGlu: 1.188 ± 0.022	0.749CysPhe: 0.749 ± 0.014	1.349CysGly: 1.349 ± 0.035	0.535CysHis: 0.535 ± 0.011	1.205CysIle: 1.205 ± 0.027	1.162CysLys: 1.162 ± 0.018	1.824CysLeu: 1.824 ± 0.028	0.459CysMet: 0.459 ± 0.013	1.024CysAsn: 1.024 ± 0.019	1.019CysPro: 1.019 ± 0.036	0.772CysGln: 0.772 ± 0.018	1.249CysArg: 1.249 ± 0.035	1.581CysSer: 1.581 ± 0.03	1.215CysThr: 1.215 ± 0.026	1.298CysVal: 1.298 ± 0.03	0.244CysTrp: 0.244 ± 0.007	0.603CysTyr: 0.603 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	3.452AspAla: 3.452 ± 0.027	1.058AspCys: 1.058 ± 0.023	3.797AspAsp: 3.797 ± 0.038	4.19AspGlu: 4.19 ± 0.029	2.038AspPhe: 2.038 ± 0.02	3.13AspGly: 3.13 ± 0.034	1.189AspHis: 1.189 ± 0.014	3.404AspIle: 3.404 ± 0.026	3.154AspLys: 3.154 ± 0.029	4.686AspLeu: 4.686 ± 0.037	1.249AspMet: 1.249 ± 0.013	2.687AspAsn: 2.687 ± 0.025	2.361AspPro: 2.361 ± 0.035	1.647AspGln: 1.647 ± 0.019	2.957AspArg: 2.957 ± 0.032	4.192AspSer: 4.192 ± 0.031	3.045AspThr: 3.045 ± 0.023	3.782AspVal: 3.782 ± 0.026	0.624AspTrp: 0.624 ± 0.011	1.786AspTyr: 1.786 ± 0.016	0.001AspXaa: 0.001 ± 0.0
Glu	4.114GluAla: 4.114 ± 0.036	1.274GluCys: 1.274 ± 0.037	4.107GluAsp: 4.107 ± 0.031	6.34GluGlu: 6.34 ± 0.072	2.065GluPhe: 2.065 ± 0.022	3.006GluGly: 3.006 ± 0.032	1.581GluHis: 1.581 ± 0.019	3.923GluIle: 3.923 ± 0.039	4.996GluLys: 4.996 ± 0.05	5.586GluLeu: 5.586 ± 0.046	1.675GluMet: 1.675 ± 0.017	3.674GluAsn: 3.674 ± 0.028	2.394GluPro: 2.394 ± 0.025	2.747GluGln: 2.747 ± 0.026	4.415GluArg: 4.415 ± 0.037	4.648GluSer: 4.648 ± 0.038	3.846GluThr: 3.846 ± 0.035	3.617GluVal: 3.617 ± 0.03	0.687GluTrp: 0.687 ± 0.011	1.956GluTyr: 1.956 ± 0.019	0.001GluXaa: 0.001 ± 0.0
Phe	2.255PheAla: 2.255 ± 0.02	0.822PheCys: 0.822 ± 0.012	1.952PheAsp: 1.952 ± 0.019	2.05PheGlu: 2.05 ± 0.019	1.523PhePhe: 1.523 ± 0.026	2.088PheGly: 2.088 ± 0.023	1.001PheHis: 1.001 ± 0.012	2.037PheIle: 2.037 ± 0.023	1.902PheLys: 1.902 ± 0.021	3.626PheLeu: 3.626 ± 0.032	0.816PheMet: 0.816 ± 0.011	1.646PheAsn: 1.646 ± 0.018	1.666PhePro: 1.666 ± 0.018	1.395PheGln: 1.395 ± 0.016	1.915PheArg: 1.915 ± 0.019	2.793PheSer: 2.793 ± 0.021	2.103PheThr: 2.103 ± 0.02	2.435PheVal: 2.435 ± 0.02	0.451PheTrp: 0.451 ± 0.009	1.27PheTyr: 1.27 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	3.337GlyAla: 3.337 ± 0.03	1.062GlyCys: 1.062 ± 0.021	2.833GlyAsp: 2.833 ± 0.029	3.189GlyGlu: 3.189 ± 0.033	2.01GlyPhe: 2.01 ± 0.025	4.248GlyGly: 4.248 ± 0.062	1.409GlyHis: 1.409 ± 0.02	3.122GlyIle: 3.122 ± 0.026	3.326GlyLys: 3.326 ± 0.029	4.356GlyLeu: 4.356 ± 0.033	1.238GlyMet: 1.238 ± 0.017	2.643GlyAsn: 2.643 ± 0.026	2.358GlyPro: 2.358 ± 0.042	2.006GlyGln: 2.006 ± 0.023	3.344GlyArg: 3.344 ± 0.03	4.47GlySer: 4.47 ± 0.043	3.275GlyThr: 3.275 ± 0.029	3.254GlyVal: 3.254 ± 0.026	0.66GlyTrp: 0.66 ± 0.012	1.912GlyTyr: 1.912 ± 0.027	0.001GlyXaa: 0.001 ± 0.0
His	1.53HisAla: 1.53 ± 0.017	0.611HisCys: 0.611 ± 0.013	1.198HisAsp: 1.198 ± 0.016	1.462HisGlu: 1.462 ± 0.016	1.03HisPhe: 1.03 ± 0.013	1.428HisGly: 1.428 ± 0.02	1.133HisHis: 1.133 ± 0.028	1.385HisIle: 1.385 ± 0.015	1.304HisLys: 1.304 ± 0.015	2.411HisLeu: 2.411 ± 0.023	0.627HisMet: 0.627 ± 0.01	1.148HisAsn: 1.148 ± 0.015	1.387HisPro: 1.387 ± 0.017	1.132HisGln: 1.132 ± 0.016	1.721HisArg: 1.721 ± 0.018	1.967HisSer: 1.967 ± 0.02	1.47HisThr: 1.47 ± 0.092	1.71HisVal: 1.71 ± 0.018	0.294HisTrp: 0.294 ± 0.007	0.899HisTyr: 0.899 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.851IleAla: 3.851 ± 0.024	1.276IleCys: 1.276 ± 0.024	3.172IleAsp: 3.172 ± 0.023	3.56IleGlu: 3.56 ± 0.034	2.262IlePhe: 2.262 ± 0.025	2.994IleGly: 2.994 ± 0.026	1.369IleHis: 1.369 ± 0.016	3.334IleIle: 3.334 ± 0.032	3.349IleLys: 3.349 ± 0.028	5.486IleLeu: 5.486 ± 0.04	1.309IleMet: 1.309 ± 0.017	2.713IleAsn: 2.713 ± 0.024	2.74IlePro: 2.74 ± 0.023	2.139IleGln: 2.139 ± 0.019	3.047IleArg: 3.047 ± 0.021	4.402IleSer: 4.402 ± 0.032	3.352IleThr: 3.352 ± 0.028	3.696IleVal: 3.696 ± 0.026	0.581IleTrp: 0.581 ± 0.01	1.772IleTyr: 1.772 ± 0.017	0.001IleXaa: 0.001 ± 0.0
Lys	3.364LysAla: 3.364 ± 0.029	1.21LysCys: 1.21 ± 0.023	3.446LysAsp: 3.446 ± 0.03	4.673LysGlu: 4.673 ± 0.044	1.97LysPhe: 1.97 ± 0.018	2.59LysGly: 2.59 ± 0.029	1.54LysHis: 1.54 ± 0.017	3.636LysIle: 3.636 ± 0.031	4.919LysLys: 4.919 ± 0.057	5.597LysLeu: 5.597 ± 0.044	1.516LysMet: 1.516 ± 0.016	2.977LysAsn: 2.977 ± 0.024	2.742LysPro: 2.742 ± 0.038	2.57LysGln: 2.57 ± 0.025	4.148LysArg: 4.148 ± 0.033	4.467LysSer: 4.467 ± 0.037	3.447LysThr: 3.447 ± 0.028	3.345LysVal: 3.345 ± 0.026	0.676LysTrp: 0.676 ± 0.011	2.044LysTyr: 2.044 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	6.017LeuAla: 6.017 ± 0.044	1.837LeuCys: 1.837 ± 0.02	4.754LeuAsp: 4.754 ± 0.036	5.979LeuGlu: 5.979 ± 0.051	3.214LeuPhe: 3.214 ± 0.035	4.37LeuGly: 4.37 ± 0.03	2.601LeuHis: 2.601 ± 0.025	4.606LeuIle: 4.606 ± 0.038	5.645LeuLys: 5.645 ± 0.042	8.974LeuLeu: 8.974 ± 0.063	2.071LeuMet: 2.071 ± 0.02	4.107LeuAsn: 4.107 ± 0.027	4.791LeuPro: 4.791 ± 0.029	4.478LeuGln: 4.478 ± 0.037	5.737LeuArg: 5.737 ± 0.039	7.123LeuSer: 7.123 ± 0.044	5.058LeuThr: 5.058 ± 0.033	5.068LeuVal: 5.068 ± 0.037	0.987LeuTrp: 0.987 ± 0.013	2.766LeuTyr: 2.766 ± 0.024	0.003LeuXaa: 0.003 ± 0.001
Met	1.575MetAla: 1.575 ± 0.017	0.472MetCys: 0.472 ± 0.009	1.342MetAsp: 1.342 ± 0.018	1.721MetGlu: 1.721 ± 0.017	0.855MetPhe: 0.855 ± 0.012	1.115MetGly: 1.115 ± 0.015	0.609MetHis: 0.609 ± 0.009	1.3MetIle: 1.3 ± 0.018	1.553MetLys: 1.553 ± 0.018	2.146MetLeu: 2.146 ± 0.023	0.685MetMet: 0.685 ± 0.013	1.092MetAsn: 1.092 ± 0.016	1.152MetPro: 1.152 ± 0.014	1.116MetGln: 1.116 ± 0.013	1.374MetArg: 1.374 ± 0.016	1.812MetSer: 1.812 ± 0.019	1.331MetThr: 1.331 ± 0.016	1.261MetVal: 1.261 ± 0.015	0.263MetTrp: 0.263 ± 0.007	0.776MetTyr: 0.776 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.186AsnAla: 3.186 ± 0.032	0.933AsnCys: 0.933 ± 0.018	2.637AsnAsp: 2.637 ± 0.024	3.119AsnGlu: 3.119 ± 0.024	1.77AsnPhe: 1.77 ± 0.017	2.85AsnGly: 2.85 ± 0.03	1.121AsnHis: 1.121 ± 0.015	3.111AsnIle: 3.111 ± 0.028	2.8AsnLys: 2.8 ± 0.024	4.288AsnLeu: 4.288 ± 0.031	1.135AsnMet: 1.135 ± 0.014	2.846AsnAsn: 2.846 ± 0.032	2.203AsnPro: 2.203 ± 0.03	1.719AsnGln: 1.719 ± 0.019	2.527AsnArg: 2.527 ± 0.02	3.731AsnSer: 3.731 ± 0.027	2.677AsnThr: 2.677 ± 0.026	3.544AsnVal: 3.544 ± 0.026	0.493AsnTrp: 0.493 ± 0.009	1.566AsnTyr: 1.566 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	3.279ProAla: 3.279 ± 0.027	0.877ProCys: 0.877 ± 0.044	2.552ProAsp: 2.552 ± 0.022	3.121ProGlu: 3.121 ± 0.033	1.6ProPhe: 1.6 ± 0.018	2.884ProGly: 2.884 ± 0.058	1.268ProHis: 1.268 ± 0.016	2.55ProIle: 2.55 ± 0.023	2.542ProLys: 2.542 ± 0.027	4.131ProLeu: 4.131 ± 0.029	1.035ProMet: 1.035 ± 0.015	2.107ProAsn: 2.107 ± 0.025	4.143ProPro: 4.143 ± 0.067	2.021ProGln: 2.021 ± 0.028	2.954ProArg: 2.954 ± 0.029	4.326ProSer: 4.326 ± 0.043	3.11ProThr: 3.11 ± 0.031	3.196ProVal: 3.196 ± 0.03	0.492ProTrp: 0.492 ± 0.009	1.528ProTyr: 1.528 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	2.521GlnAla: 2.521 ± 0.025	0.811GlnCys: 0.811 ± 0.021	1.998GlnAsp: 1.998 ± 0.017	2.931GlnGlu: 2.931 ± 0.027	1.338GlnPhe: 1.338 ± 0.017	1.791GlnGly: 1.791 ± 0.023	1.25GlnHis: 1.25 ± 0.018	2.166GlnIle: 2.166 ± 0.02	2.482GlnLys: 2.482 ± 0.025	3.894GlnLeu: 3.894 ± 0.034	0.992GlnMet: 0.992 ± 0.016	2.046GlnAsn: 2.046 ± 0.023	2.053GlnPro: 2.053 ± 0.027	3.522GlnGln: 3.522 ± 0.083	2.756GlnArg: 2.756 ± 0.024	3.02GlnSer: 3.02 ± 0.032	2.238GlnThr: 2.238 ± 0.021	2.287GlnVal: 2.287 ± 0.021	0.473GlnTrp: 0.473 ± 0.009	1.289GlnTyr: 1.289 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	3.675ArgAla: 3.675 ± 0.028	1.24ArgCys: 1.24 ± 0.023	3.32ArgAsp: 3.32 ± 0.03	4.18ArgGlu: 4.18 ± 0.032	2.11ArgPhe: 2.11 ± 0.019	3.247ArgGly: 3.247 ± 0.032	1.716ArgHis: 1.716 ± 0.015	3.345ArgIle: 3.345 ± 0.027	4.197ArgLys: 4.197 ± 0.034	5.317ArgLeu: 5.317 ± 0.035	1.407ArgMet: 1.407 ± 0.016	3.074ArgAsn: 3.074 ± 0.023	2.727ArgPro: 2.727 ± 0.03	2.552ArgGln: 2.552 ± 0.022	5.091ArgArg: 5.091 ± 0.045	4.848ArgSer: 4.848 ± 0.048	3.271ArgThr: 3.271 ± 0.024	3.391ArgVal: 3.391 ± 0.027	0.737ArgTrp: 0.737 ± 0.011	1.99ArgTyr: 1.99 ± 0.016	0.001ArgXaa: 0.001 ± 0.0
Ser	5.069SerAla: 5.069 ± 0.036	1.515SerCys: 1.515 ± 0.029	4.275SerAsp: 4.275 ± 0.032	4.675SerGlu: 4.675 ± 0.032	2.752SerPhe: 2.752 ± 0.028	4.579SerGly: 4.579 ± 0.037	1.894SerHis: 1.894 ± 0.021	4.132SerIle: 4.132 ± 0.027	4.416SerLys: 4.416 ± 0.033	7.071SerLeu: 7.071 ± 0.04	1.792SerMet: 1.792 ± 0.022	3.905SerAsn: 3.905 ± 0.032	4.505SerPro: 4.505 ± 0.049	3.109SerGln: 3.109 ± 0.033	4.839SerArg: 4.839 ± 0.044	8.506SerSer: 8.506 ± 0.077	5.273SerThr: 5.273 ± 0.04	4.879SerVal: 4.879 ± 0.027	0.847SerTrp: 0.847 ± 0.013	2.298SerTyr: 2.298 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	4.139ThrAla: 4.139 ± 0.034	1.264ThrCys: 1.264 ± 0.027	3.014ThrAsp: 3.014 ± 0.022	3.66ThrGlu: 3.66 ± 0.035	2.148ThrPhe: 2.148 ± 0.022	3.289ThrGly: 3.289 ± 0.027	1.383ThrHis: 1.383 ± 0.093	3.381ThrIle: 3.381 ± 0.025	3.279ThrLys: 3.279 ± 0.031	5.403ThrLeu: 5.403 ± 0.032	1.432ThrMet: 1.432 ± 0.014	2.662ThrAsn: 2.662 ± 0.024	3.3ThrPro: 3.3 ± 0.034	2.106ThrGln: 2.106 ± 0.019	3.296ThrArg: 3.296 ± 0.022	5.264ThrSer: 5.264 ± 0.041	4.411ThrThr: 4.411 ± 0.056	4.0ThrVal: 4.0 ± 0.029	0.663ThrTrp: 0.663 ± 0.011	1.776ThrTyr: 1.776 ± 0.016	0.001ThrXaa: 0.001 ± 0.0
Val	4.329ValAla: 4.329 ± 0.024	1.36ValCys: 1.36 ± 0.029	3.375ValAsp: 3.375 ± 0.023	3.955ValGlu: 3.955 ± 0.035	2.267ValPhe: 2.267 ± 0.021	3.082ValGly: 3.082 ± 0.029	1.592ValHis: 1.592 ± 0.018	3.579ValIle: 3.579 ± 0.024	3.603ValLys: 3.603 ± 0.029	5.556ValLeu: 5.556 ± 0.039	1.427ValMet: 1.427 ± 0.016	2.847ValAsn: 2.847 ± 0.029	3.304ValPro: 3.304 ± 0.031	2.587ValGln: 2.587 ± 0.023	3.416ValArg: 3.416 ± 0.025	4.754ValSer: 4.754 ± 0.031	4.049ValThr: 4.049 ± 0.028	3.975ValVal: 3.975 ± 0.034	0.686ValTrp: 0.686 ± 0.011	1.898ValTyr: 1.898 ± 0.019	0.001ValXaa: 0.001 ± 0.0
Trp	0.581TrpAla: 0.581 ± 0.009	0.235TrpCys: 0.235 ± 0.006	0.587TrpAsp: 0.587 ± 0.011	0.623TrpGlu: 0.623 ± 0.012	0.438TrpPhe: 0.438 ± 0.011	0.544TrpGly: 0.544 ± 0.011	0.277TrpHis: 0.277 ± 0.007	0.711TrpIle: 0.711 ± 0.012	0.736TrpLys: 0.736 ± 0.013	1.1TrpLeu: 1.1 ± 0.015	0.309TrpMet: 0.309 ± 0.011	0.572TrpAsn: 0.572 ± 0.011	0.509TrpPro: 0.509 ± 0.008	0.494TrpGln: 0.494 ± 0.008	0.758TrpArg: 0.758 ± 0.012	0.835TrpSer: 0.835 ± 0.011	0.625TrpThr: 0.625 ± 0.009	0.532TrpVal: 0.532 ± 0.009	0.201TrpTrp: 0.201 ± 0.006	0.411TrpTyr: 0.411 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.907TyrAla: 1.907 ± 0.018	0.718TyrCys: 0.718 ± 0.012	1.699TyrAsp: 1.699 ± 0.02	1.878TyrGlu: 1.878 ± 0.019	1.416TyrPhe: 1.416 ± 0.018	1.838TyrGly: 1.838 ± 0.02	0.887TyrHis: 0.887 ± 0.012	1.82TyrIle: 1.82 ± 0.019	1.809TyrLys: 1.809 ± 0.017	2.9TyrLeu: 2.9 ± 0.023	0.752TyrMet: 0.752 ± 0.012	1.612TyrAsn: 1.612 ± 0.018	1.434TyrPro: 1.434 ± 0.018	1.25TyrGln: 1.25 ± 0.016	1.841TyrArg: 1.841 ± 0.019	2.245TyrSer: 2.245 ± 0.021	1.778TyrThr: 1.778 ± 0.019	2.098TyrVal: 2.098 ± 0.02	0.363TyrTrp: 0.363 ± 0.008	1.223TyrTyr: 1.223 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	1.04XaaXaa: 1.04 ± 0.169

Statistics based on 16497 proteins (6790250 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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