Amino acid dipepetide frequency for Serendipita vermifera MAFF 305830

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.248AlaAla: 8.248 ± 0.059	1.036AlaCys: 1.036 ± 0.013	3.558AlaAsp: 3.558 ± 0.027	4.649AlaGlu: 4.649 ± 0.038	3.132AlaPhe: 3.132 ± 0.025	5.264AlaGly: 5.264 ± 0.037	1.861AlaHis: 1.861 ± 0.017	4.555AlaIle: 4.555 ± 0.034	3.844AlaLys: 3.844 ± 0.043	7.982AlaLeu: 7.982 ± 0.044	1.855AlaMet: 1.855 ± 0.017	2.968AlaAsn: 2.968 ± 0.026	4.87AlaPro: 4.87 ± 0.043	3.099AlaGln: 3.099 ± 0.029	4.694AlaArg: 4.694 ± 0.028	7.596AlaSer: 7.596 ± 0.041	5.435AlaThr: 5.435 ± 0.037	5.03AlaVal: 5.03 ± 0.035	1.115AlaTrp: 1.115 ± 0.013	2.146AlaTyr: 2.146 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.894CysAla: 0.894 ± 0.015	0.224CysCys: 0.224 ± 0.008	0.657CysAsp: 0.657 ± 0.011	0.59CysGlu: 0.59 ± 0.01	0.493CysPhe: 0.493 ± 0.009	0.968CysGly: 0.968 ± 0.014	0.35CysHis: 0.35 ± 0.008	0.75CysIle: 0.75 ± 0.012	0.55CysLys: 0.55 ± 0.009	1.319CysLeu: 1.319 ± 0.017	0.258CysMet: 0.258 ± 0.006	0.435CysAsn: 0.435 ± 0.009	0.751CysPro: 0.751 ± 0.01	0.45CysGln: 0.45 ± 0.009	0.751CysArg: 0.751 ± 0.011	0.943CysSer: 0.943 ± 0.012	0.753CysThr: 0.753 ± 0.012	0.798CysVal: 0.798 ± 0.012	0.201CysTrp: 0.201 ± 0.005	0.322CysTyr: 0.322 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.792AspAla: 4.792 ± 0.033	0.604AspCys: 0.604 ± 0.011	3.671AspAsp: 3.671 ± 0.032	4.08AspGlu: 4.08 ± 0.034	1.888AspPhe: 1.888 ± 0.02	3.96AspGly: 3.96 ± 0.033	1.25AspHis: 1.25 ± 0.014	3.069AspIle: 3.069 ± 0.024	2.091AspLys: 2.091 ± 0.022	4.875AspLeu: 4.875 ± 0.036	1.219AspMet: 1.219 ± 0.013	1.685AspAsn: 1.685 ± 0.018	3.275AspPro: 3.275 ± 0.026	1.696AspGln: 1.696 ± 0.02	2.688AspArg: 2.688 ± 0.025	3.935AspSer: 3.935 ± 0.027	2.974AspThr: 2.974 ± 0.024	3.478AspVal: 3.478 ± 0.027	0.876AspTrp: 0.876 ± 0.012	1.407AspTyr: 1.407 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.0GluAla: 5.0 ± 0.039	0.713GluCys: 0.713 ± 0.012	3.872GluAsp: 3.872 ± 0.033	5.357GluGlu: 5.357 ± 0.05	1.835GluPhe: 1.835 ± 0.018	3.505GluGly: 3.505 ± 0.026	1.456GluHis: 1.456 ± 0.018	3.022GluIle: 3.022 ± 0.026	3.192GluLys: 3.192 ± 0.03	5.225GluLeu: 5.225 ± 0.037	1.449GluMet: 1.449 ± 0.016	2.069GluAsn: 2.069 ± 0.019	2.662GluPro: 2.662 ± 0.026	2.262GluGln: 2.262 ± 0.023	4.041GluArg: 4.041 ± 0.033	4.1GluSer: 4.1 ± 0.028	3.462GluThr: 3.462 ± 0.028	3.521GluVal: 3.521 ± 0.031	0.935GluTrp: 0.935 ± 0.013	1.667GluTyr: 1.667 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	2.79PheAla: 2.79 ± 0.025	0.529PheCys: 0.529 ± 0.008	2.131PheAsp: 2.131 ± 0.018	2.095PheGlu: 2.095 ± 0.022	1.485PhePhe: 1.485 ± 0.017	2.618PheGly: 2.618 ± 0.025	0.917PheHis: 0.917 ± 0.013	1.914PheIle: 1.914 ± 0.018	1.497PheLys: 1.497 ± 0.017	3.442PheLeu: 3.442 ± 0.027	0.744PheMet: 0.744 ± 0.011	1.316PheAsn: 1.316 ± 0.017	2.025PhePro: 2.025 ± 0.02	1.275PheGln: 1.275 ± 0.015	1.897PheArg: 1.897 ± 0.02	3.137PheSer: 3.137 ± 0.028	2.166PheThr: 2.166 ± 0.02	2.391PheVal: 2.391 ± 0.021	0.607PheTrp: 0.607 ± 0.01	0.994PheTyr: 0.994 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.012GlyAla: 5.012 ± 0.036	0.89GlyCys: 0.89 ± 0.016	3.326GlyAsp: 3.326 ± 0.031	3.489GlyGlu: 3.489 ± 0.027	2.392GlyPhe: 2.392 ± 0.023	5.576GlyGly: 5.576 ± 0.052	1.992GlyHis: 1.992 ± 0.027	3.359GlyIle: 3.359 ± 0.026	3.286GlyLys: 3.286 ± 0.027	5.428GlyLeu: 5.428 ± 0.037	1.564GlyMet: 1.564 ± 0.016	2.431GlyAsn: 2.431 ± 0.021	3.378GlyPro: 3.378 ± 0.025	2.259GlyGln: 2.259 ± 0.022	3.948GlyArg: 3.948 ± 0.028	6.063GlySer: 6.063 ± 0.049	4.301GlyThr: 4.301 ± 0.029	4.157GlyVal: 4.157 ± 0.027	1.079GlyTrp: 1.079 ± 0.013	1.84GlyTyr: 1.84 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.883HisAla: 1.883 ± 0.019	0.327HisCys: 0.327 ± 0.007	1.226HisAsp: 1.226 ± 0.016	1.289HisGlu: 1.289 ± 0.016	0.974HisPhe: 0.974 ± 0.013	1.617HisGly: 1.617 ± 0.017	0.891HisHis: 0.891 ± 0.016	1.362HisIle: 1.362 ± 0.015	0.912HisLys: 0.912 ± 0.012	2.681HisLeu: 2.681 ± 0.025	0.493HisMet: 0.493 ± 0.009	0.825HisAsn: 0.825 ± 0.013	1.99HisPro: 1.99 ± 0.026	1.027HisGln: 1.027 ± 0.014	1.538HisArg: 1.538 ± 0.016	2.144HisSer: 2.144 ± 0.021	1.541HisThr: 1.541 ± 0.02	1.509HisVal: 1.509 ± 0.016	0.377HisTrp: 0.377 ± 0.008	0.68HisTyr: 0.68 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.165IleAla: 4.165 ± 0.028	0.78IleCys: 0.78 ± 0.013	2.771IleAsp: 2.771 ± 0.024	2.892IleGlu: 2.892 ± 0.025	1.974IlePhe: 1.974 ± 0.02	3.14IleGly: 3.14 ± 0.024	1.331IleHis: 1.331 ± 0.015	2.761IleIle: 2.761 ± 0.024	2.324IleLys: 2.324 ± 0.019	5.144IleLeu: 5.144 ± 0.041	1.034IleMet: 1.034 ± 0.015	1.829IleAsn: 1.829 ± 0.018	3.382IlePro: 3.382 ± 0.024	1.99IleGln: 1.99 ± 0.018	3.244IleArg: 3.244 ± 0.027	4.381IleSer: 4.381 ± 0.031	3.053IleThr: 3.053 ± 0.026	3.455IleVal: 3.455 ± 0.029	0.926IleTrp: 0.926 ± 0.017	1.433IleTyr: 1.433 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.137LysAla: 4.137 ± 0.043	0.53LysCys: 0.53 ± 0.011	2.571LysAsp: 2.571 ± 0.02	3.324LysGlu: 3.324 ± 0.033	1.345LysPhe: 1.345 ± 0.016	2.962LysGly: 2.962 ± 0.036	1.103LysHis: 1.103 ± 0.017	2.13LysIle: 2.13 ± 0.02	2.916LysLys: 2.916 ± 0.036	4.163LysLeu: 4.163 ± 0.03	1.0LysMet: 1.0 ± 0.014	1.545LysAsn: 1.545 ± 0.016	2.602LysPro: 2.602 ± 0.026	1.803LysGln: 1.803 ± 0.018	3.484LysArg: 3.484 ± 0.028	3.344LysSer: 3.344 ± 0.027	2.728LysThr: 2.728 ± 0.028	2.764LysVal: 2.764 ± 0.025	0.706LysTrp: 0.706 ± 0.012	1.236LysTyr: 1.236 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	7.903LeuAla: 7.903 ± 0.047	1.247LeuCys: 1.247 ± 0.016	5.197LeuAsp: 5.197 ± 0.03	5.955LeuGlu: 5.955 ± 0.043	3.431LeuPhe: 3.431 ± 0.024	5.943LeuGly: 5.943 ± 0.039	2.423LeuHis: 2.423 ± 0.021	4.197LeuIle: 4.197 ± 0.03	4.591LeuLys: 4.591 ± 0.035	8.961LeuLeu: 8.961 ± 0.057	1.782LeuMet: 1.782 ± 0.015	3.269LeuAsn: 3.269 ± 0.025	5.954LeuPro: 5.954 ± 0.037	3.996LeuGln: 3.996 ± 0.032	6.072LeuArg: 6.072 ± 0.04	7.854LeuSer: 7.854 ± 0.042	5.149LeuThr: 5.149 ± 0.031	5.914LeuVal: 5.914 ± 0.036	1.358LeuTrp: 1.358 ± 0.017	2.392LeuTyr: 2.392 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.955MetAla: 1.955 ± 0.017	0.228MetCys: 0.228 ± 0.006	1.296MetAsp: 1.296 ± 0.017	1.425MetGlu: 1.425 ± 0.016	0.678MetPhe: 0.678 ± 0.009	1.366MetGly: 1.366 ± 0.018	0.533MetHis: 0.533 ± 0.009	1.035MetIle: 1.035 ± 0.012	1.036MetLys: 1.036 ± 0.014	1.79MetLeu: 1.79 ± 0.017	0.543MetMet: 0.543 ± 0.009	0.789MetAsn: 0.789 ± 0.012	1.271MetPro: 1.271 ± 0.015	0.859MetGln: 0.859 ± 0.013	1.315MetArg: 1.315 ± 0.016	1.928MetSer: 1.928 ± 0.018	1.267MetThr: 1.267 ± 0.013	1.261MetVal: 1.261 ± 0.014	0.3MetTrp: 0.3 ± 0.006	0.493MetTyr: 0.493 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.228AsnAla: 3.228 ± 0.027	0.41AsnCys: 0.41 ± 0.007	1.855AsnAsp: 1.855 ± 0.019	1.972AsnGlu: 1.972 ± 0.019	1.21AsnPhe: 1.21 ± 0.014	2.852AsnGly: 2.852 ± 0.025	0.851AsnHis: 0.851 ± 0.013	2.0AsnIle: 2.0 ± 0.021	1.427AsnLys: 1.427 ± 0.015	3.584AsnLeu: 3.584 ± 0.028	0.76AsnMet: 0.76 ± 0.012	1.508AsnAsn: 1.508 ± 0.024	2.51AsnPro: 2.51 ± 0.022	1.362AsnGln: 1.362 ± 0.015	1.954AsnArg: 1.954 ± 0.017	2.851AsnSer: 2.851 ± 0.025	2.269AsnThr: 2.269 ± 0.022	2.382AsnVal: 2.382 ± 0.022	0.54AsnTrp: 0.54 ± 0.011	0.944AsnTyr: 0.944 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.037ProAla: 5.037 ± 0.044	0.548ProCys: 0.548 ± 0.011	3.222ProAsp: 3.222 ± 0.032	3.341ProGlu: 3.341 ± 0.028	2.201ProPhe: 2.201 ± 0.021	3.73ProGly: 3.73 ± 0.031	1.497ProHis: 1.497 ± 0.017	2.941ProIle: 2.941 ± 0.023	2.574ProLys: 2.574 ± 0.026	5.527ProLeu: 5.527 ± 0.035	1.154ProMet: 1.154 ± 0.016	2.599ProAsn: 2.599 ± 0.022	5.552ProPro: 5.552 ± 0.06	2.231ProGln: 2.231 ± 0.021	3.33ProArg: 3.33 ± 0.028	6.625ProSer: 6.625 ± 0.049	4.405ProThr: 4.405 ± 0.034	3.787ProVal: 3.787 ± 0.031	0.712ProTrp: 0.712 ± 0.012	1.592ProTyr: 1.592 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.344GlnAla: 3.344 ± 0.027	0.473GlnCys: 0.473 ± 0.011	1.865GlnAsp: 1.865 ± 0.02	2.291GlnGlu: 2.291 ± 0.026	1.21GlnPhe: 1.21 ± 0.013	2.263GlnGly: 2.263 ± 0.024	1.002GlnHis: 1.002 ± 0.014	1.855GlnIle: 1.855 ± 0.019	1.746GlnLys: 1.746 ± 0.018	3.535GlnLeu: 3.535 ± 0.027	0.846GlnMet: 0.846 ± 0.013	1.471GlnAsn: 1.471 ± 0.014	2.331GlnPro: 2.331 ± 0.027	2.178GlnGln: 2.178 ± 0.042	2.61GlnArg: 2.61 ± 0.024	3.017GlnSer: 3.017 ± 0.023	2.325GlnThr: 2.325 ± 0.021	2.094GlnVal: 2.094 ± 0.021	0.586GlnTrp: 0.586 ± 0.011	1.052GlnTyr: 1.052 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.683ArgAla: 4.683 ± 0.031	0.725ArgCys: 0.725 ± 0.012	3.154ArgAsp: 3.154 ± 0.024	3.589ArgGlu: 3.589 ± 0.029	2.253ArgPhe: 2.253 ± 0.023	3.5ArgGly: 3.5 ± 0.028	1.638ArgHis: 1.638 ± 0.019	3.423ArgIle: 3.423 ± 0.03	3.297ArgLys: 3.297 ± 0.024	5.966ArgLeu: 5.966 ± 0.038	1.357ArgMet: 1.357 ± 0.017	2.267ArgAsn: 2.267 ± 0.016	3.44ArgPro: 3.44 ± 0.028	2.359ArgGln: 2.359 ± 0.024	4.919ArgArg: 4.919 ± 0.039	4.859ArgSer: 4.859 ± 0.036	3.452ArgThr: 3.452 ± 0.026	3.686ArgVal: 3.686 ± 0.027	0.943ArgTrp: 0.943 ± 0.015	1.643ArgTyr: 1.643 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.513SerAla: 6.513 ± 0.037	0.929SerCys: 0.929 ± 0.015	4.013SerAsp: 4.013 ± 0.029	4.031SerGlu: 4.031 ± 0.027	3.251SerPhe: 3.251 ± 0.028	5.794SerGly: 5.794 ± 0.044	2.172SerHis: 2.172 ± 0.021	4.484SerIle: 4.484 ± 0.026	3.717SerLys: 3.717 ± 0.034	8.15SerLeu: 8.15 ± 0.049	1.796SerMet: 1.796 ± 0.019	3.291SerAsn: 3.291 ± 0.025	6.051SerPro: 6.051 ± 0.059	3.301SerGln: 3.301 ± 0.027	5.172SerArg: 5.172 ± 0.036	9.618SerSer: 9.618 ± 0.073	6.312SerThr: 6.312 ± 0.039	4.955SerVal: 4.955 ± 0.039	1.137SerTrp: 1.137 ± 0.015	2.165SerTyr: 2.165 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	4.927ThrAla: 4.927 ± 0.035	0.778ThrCys: 0.778 ± 0.013	2.652ThrAsp: 2.652 ± 0.018	2.975ThrGlu: 2.975 ± 0.023	2.341ThrPhe: 2.341 ± 0.02	4.248ThrGly: 4.248 ± 0.033	1.392ThrHis: 1.392 ± 0.016	3.646ThrIle: 3.646 ± 0.03	2.638ThrLys: 2.638 ± 0.03	6.076ThrLeu: 6.076 ± 0.034	1.252ThrMet: 1.252 ± 0.013	2.207ThrAsn: 2.207 ± 0.019	4.633ThrPro: 4.633 ± 0.037	2.109ThrGln: 2.109 ± 0.019	3.57ThrArg: 3.57 ± 0.026	6.041ThrSer: 6.041 ± 0.04	4.62ThrThr: 4.62 ± 0.038	3.951ThrVal: 3.951 ± 0.03	0.815ThrTrp: 0.815 ± 0.013	1.692ThrTyr: 1.692 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.289ValAla: 5.289 ± 0.034	0.869ValCys: 0.869 ± 0.012	3.668ValAsp: 3.668 ± 0.023	3.763ValGlu: 3.763 ± 0.026	2.271ValPhe: 2.271 ± 0.023	3.745ValGly: 3.745 ± 0.031	1.55ValHis: 1.55 ± 0.015	3.263ValIle: 3.263 ± 0.026	2.812ValLys: 2.812 ± 0.025	5.869ValLeu: 5.869 ± 0.036	1.31ValMet: 1.31 ± 0.015	2.215ValAsn: 2.215 ± 0.02	3.723ValPro: 3.723 ± 0.029	2.316ValGln: 2.316 ± 0.018	3.363ValArg: 3.363 ± 0.027	4.97ValSer: 4.97 ± 0.033	3.747ValThr: 3.747 ± 0.024	4.295ValVal: 4.295 ± 0.03	1.065ValTrp: 1.065 ± 0.019	1.773ValTyr: 1.773 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.087TrpAla: 1.087 ± 0.014	0.221TrpCys: 0.221 ± 0.007	1.232TrpAsp: 1.232 ± 0.023	0.826TrpGlu: 0.826 ± 0.012	0.52TrpPhe: 0.52 ± 0.009	0.825TrpGly: 0.825 ± 0.013	0.33TrpHis: 0.33 ± 0.007	0.824TrpIle: 0.824 ± 0.013	0.857TrpLys: 0.857 ± 0.013	1.287TrpLeu: 1.287 ± 0.016	0.362TrpMet: 0.362 ± 0.008	0.718TrpAsn: 0.718 ± 0.012	0.648TrpPro: 0.648 ± 0.012	0.485TrpGln: 0.485 ± 0.008	0.995TrpArg: 0.995 ± 0.012	1.203TrpSer: 1.203 ± 0.014	0.959TrpThr: 0.959 ± 0.013	0.929TrpVal: 0.929 ± 0.013	0.288TrpTrp: 0.288 ± 0.007	0.402TrpTyr: 0.402 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.05TyrAla: 2.05 ± 0.018	0.395TyrCys: 0.395 ± 0.007	1.579TyrAsp: 1.579 ± 0.018	1.415TyrGlu: 1.415 ± 0.017	1.082TyrPhe: 1.082 ± 0.014	1.895TyrGly: 1.895 ± 0.021	0.747TyrHis: 0.747 ± 0.012	1.419TyrIle: 1.419 ± 0.017	1.083TyrLys: 1.083 ± 0.014	2.584TyrLeu: 2.584 ± 0.02	0.589TyrMet: 0.589 ± 0.01	1.036TyrAsn: 1.036 ± 0.014	1.558TyrPro: 1.558 ± 0.018	1.04TyrGln: 1.04 ± 0.013	1.566TyrArg: 1.566 ± 0.019	2.244TyrSer: 2.244 ± 0.025	1.646TyrThr: 1.646 ± 0.017	1.517TyrVal: 1.517 ± 0.017	0.429TyrTrp: 0.429 ± 0.01	0.876TyrTyr: 0.876 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 15021 proteins (6167058 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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