Amino acid dipepetide frequency for Dragonfly larvae associated circular virus-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.323AlaAla: 4.323 ± 0.513
2.882AlaCys: 2.882 ± 1.752
1.441AlaAsp: 1.441 ± 1.239
2.882AlaGlu: 2.882 ± 0.363
1.441AlaPhe: 1.441 ± 0.876
5.764AlaGly: 5.764 ± 1.39
0.0AlaHis: 0.0 ± 0.0
4.323AlaIle: 4.323 ± 1.601
4.323AlaLys: 4.323 ± 0.513
7.205AlaLeu: 7.205 ± 0.151
1.441AlaMet: 1.441 ± 1.239
5.764AlaAsn: 5.764 ± 1.39
5.764AlaPro: 5.764 ± 1.39
2.882AlaGln: 2.882 ± 2.478
0.0AlaArg: 0.0 ± 0.0
4.323AlaSer: 4.323 ± 2.628
2.882AlaThr: 2.882 ± 1.752
2.882AlaVal: 2.882 ± 1.752
1.441AlaTrp: 1.441 ± 0.876
4.323AlaTyr: 4.323 ± 0.513
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.882CysAsp: 2.882 ± 1.752
0.0CysGlu: 0.0 ± 0.0
2.882CysPhe: 2.882 ± 0.363
1.441CysGly: 1.441 ± 1.239
1.441CysHis: 1.441 ± 1.239
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.441CysAsn: 1.441 ± 0.876
0.0CysPro: 0.0 ± 0.0
1.441CysGln: 1.441 ± 0.876
0.0CysArg: 0.0 ± 0.0
1.441CysSer: 1.441 ± 1.239
0.0CysThr: 0.0 ± 0.0
4.323CysVal: 4.323 ± 1.601
0.0CysTrp: 0.0 ± 0.0
4.323CysTyr: 4.323 ± 1.601
0.0CysXaa: 0.0 ± 0.0
Asp
2.882AspAla: 2.882 ± 0.363
1.441AspCys: 1.441 ± 1.239
0.0AspAsp: 0.0 ± 0.0
4.323AspGlu: 4.323 ± 1.601
2.882AspPhe: 2.882 ± 0.363
0.0AspGly: 0.0 ± 0.0
2.882AspHis: 2.882 ± 0.363
2.882AspIle: 2.882 ± 0.363
1.441AspLys: 1.441 ± 0.876
4.323AspLeu: 4.323 ± 1.601
0.0AspMet: 0.0 ± 0.0
1.441AspAsn: 1.441 ± 0.876
1.441AspPro: 1.441 ± 1.239
0.0AspGln: 0.0 ± 0.0
2.882AspArg: 2.882 ± 0.363
2.882AspSer: 2.882 ± 1.752
5.764AspThr: 5.764 ± 0.725
0.0AspVal: 0.0 ± 0.0
2.882AspTrp: 2.882 ± 0.363
4.323AspTyr: 4.323 ± 1.601
0.0AspXaa: 0.0 ± 0.0
Glu
1.441GluAla: 1.441 ± 1.239
0.0GluCys: 0.0 ± 0.0
2.882GluAsp: 2.882 ± 0.363
0.0GluGlu: 0.0 ± 0.0
5.764GluPhe: 5.764 ± 0.725
1.441GluGly: 1.441 ± 0.876
0.0GluHis: 0.0 ± 0.0
1.441GluIle: 1.441 ± 1.239
1.441GluLys: 1.441 ± 0.876
5.764GluLeu: 5.764 ± 4.955
1.441GluMet: 1.441 ± 0.876
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
4.323GluGln: 4.323 ± 0.513
2.882GluArg: 2.882 ± 0.363
7.205GluSer: 7.205 ± 0.151
1.441GluThr: 1.441 ± 1.239
2.882GluVal: 2.882 ± 0.363
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.882PheAla: 2.882 ± 1.752
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
4.323PheGlu: 4.323 ± 0.513
0.0PhePhe: 0.0 ± 0.0
5.764PheGly: 5.764 ± 0.725
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.441PheLys: 1.441 ± 0.876
2.882PheLeu: 2.882 ± 1.752
0.0PheMet: 0.0 ± 0.0
2.882PheAsn: 2.882 ± 1.752
1.441PhePro: 1.441 ± 0.876
1.441PheGln: 1.441 ± 0.876
1.441PheArg: 1.441 ± 1.239
1.441PheSer: 1.441 ± 0.876
2.882PheThr: 2.882 ± 2.478
0.0PheVal: 0.0 ± 0.0
5.764PheTrp: 5.764 ± 4.955
1.441PheTyr: 1.441 ± 0.876
0.0PheXaa: 0.0 ± 0.0
Gly
7.205GlyAla: 7.205 ± 2.266
2.882GlyCys: 2.882 ± 0.363
2.882GlyAsp: 2.882 ± 0.363
1.441GlyGlu: 1.441 ± 1.239
0.0GlyPhe: 0.0 ± 0.0
2.882GlyGly: 2.882 ± 1.752
2.882GlyHis: 2.882 ± 1.752
4.323GlyIle: 4.323 ± 1.601
1.441GlyLys: 1.441 ± 1.239
4.323GlyLeu: 4.323 ± 2.628
1.441GlyMet: 1.441 ± 0.876
1.441GlyAsn: 1.441 ± 0.876
1.441GlyPro: 1.441 ± 1.239
2.882GlyGln: 2.882 ± 2.478
1.441GlyArg: 1.441 ± 0.876
8.646GlySer: 8.646 ± 1.088
10.086GlyThr: 10.086 ± 4.018
4.323GlyVal: 4.323 ± 2.628
0.0GlyTrp: 0.0 ± 0.0
5.764GlyTyr: 5.764 ± 0.725
0.0GlyXaa: 0.0 ± 0.0
His
1.441HisAla: 1.441 ± 1.239
1.441HisCys: 1.441 ± 1.239
0.0HisAsp: 0.0 ± 0.0
1.441HisGlu: 1.441 ± 1.239
0.0HisPhe: 0.0 ± 0.0
1.441HisGly: 1.441 ± 0.876
1.441HisHis: 1.441 ± 1.239
2.882HisIle: 2.882 ± 1.752
0.0HisLys: 0.0 ± 0.0
2.882HisLeu: 2.882 ± 0.363
0.0HisMet: 0.0 ± 0.0
2.882HisAsn: 2.882 ± 1.752
4.323HisPro: 4.323 ± 0.513
0.0HisGln: 0.0 ± 0.0
1.441HisArg: 1.441 ± 1.239
0.0HisSer: 0.0 ± 0.0
1.441HisThr: 1.441 ± 0.876
2.882HisVal: 2.882 ± 0.363
1.441HisTrp: 1.441 ± 1.239
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.764IleAla: 5.764 ± 3.504
1.441IleCys: 1.441 ± 0.876
4.323IleAsp: 4.323 ± 1.601
1.441IleGlu: 1.441 ± 0.876
1.441IlePhe: 1.441 ± 1.239
4.323IleGly: 4.323 ± 2.628
1.441IleHis: 1.441 ± 0.876
1.441IleIle: 1.441 ± 0.876
4.323IleLys: 4.323 ± 0.513
1.441IleLeu: 1.441 ± 1.239
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
5.764IlePro: 5.764 ± 0.725
0.0IleGln: 0.0 ± 0.0
4.323IleArg: 4.323 ± 3.716
8.646IleSer: 8.646 ± 1.027
2.882IleThr: 2.882 ± 0.363
4.323IleVal: 4.323 ± 0.513
0.0IleTrp: 0.0 ± 0.0
2.882IleTyr: 2.882 ± 1.752
0.0IleXaa: 0.0 ± 0.0
Lys
1.441LysAla: 1.441 ± 1.239
0.0LysCys: 0.0 ± 0.0
4.323LysAsp: 4.323 ± 0.513
2.882LysGlu: 2.882 ± 0.363
2.882LysPhe: 2.882 ± 2.478
4.323LysGly: 4.323 ± 0.513
2.882LysHis: 2.882 ± 1.752
7.205LysIle: 7.205 ± 4.381
5.764LysLys: 5.764 ± 3.504
1.441LysLeu: 1.441 ± 0.876
0.0LysMet: 0.0 ± 0.0
2.882LysAsn: 2.882 ± 1.752
5.764LysPro: 5.764 ± 1.39
0.0LysGln: 0.0 ± 0.0
4.323LysArg: 4.323 ± 2.628
5.764LysSer: 5.764 ± 4.955
2.882LysThr: 2.882 ± 1.752
1.441LysVal: 1.441 ± 0.876
0.0LysTrp: 0.0 ± 0.0
1.441LysTyr: 1.441 ± 0.876
0.0LysXaa: 0.0 ± 0.0
Leu
2.882LeuAla: 2.882 ± 2.478
1.441LeuCys: 1.441 ± 1.239
5.764LeuAsp: 5.764 ± 2.84
2.882LeuGlu: 2.882 ± 2.478
1.441LeuPhe: 1.441 ± 0.876
1.441LeuGly: 1.441 ± 0.876
1.441LeuHis: 1.441 ± 1.239
2.882LeuIle: 2.882 ± 0.363
2.882LeuLys: 2.882 ± 1.752
7.205LeuLeu: 7.205 ± 1.964
0.0LeuMet: 0.0 ± 0.0
2.882LeuAsn: 2.882 ± 1.752
7.205LeuPro: 7.205 ± 0.151
2.882LeuGln: 2.882 ± 0.363
7.205LeuArg: 7.205 ± 1.964
12.968LeuSer: 12.968 ± 2.689
4.323LeuThr: 4.323 ± 1.601
4.323LeuVal: 4.323 ± 0.513
0.0LeuTrp: 0.0 ± 0.0
2.882LeuTyr: 2.882 ± 1.752
0.0LeuXaa: 0.0 ± 0.0
Met
4.323MetAla: 4.323 ± 2.628
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.441MetGlu: 1.441 ± 1.239
0.0MetPhe: 0.0 ± 0.0
1.441MetGly: 1.441 ± 0.876
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.882MetLeu: 2.882 ± 0.363
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.441MetPro: 1.441 ± 1.239
1.441MetGln: 1.441 ± 0.876
0.0MetArg: 0.0 ± 0.0
1.441MetSer: 1.441 ± 1.239
1.441MetThr: 1.441 ± 0.876
1.441MetVal: 1.441 ± 0.876
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.441AsnAla: 1.441 ± 0.876
1.441AsnCys: 1.441 ± 1.239
1.441AsnAsp: 1.441 ± 0.876
1.441AsnGlu: 1.441 ± 0.876
1.441AsnPhe: 1.441 ± 0.876
1.441AsnGly: 1.441 ± 0.876
0.0AsnHis: 0.0 ± 0.0
4.323AsnIle: 4.323 ± 2.628
2.882AsnLys: 2.882 ± 1.752
2.882AsnLeu: 2.882 ± 0.363
1.441AsnMet: 1.441 ± 0.876
1.441AsnAsn: 1.441 ± 0.876
1.441AsnPro: 1.441 ± 0.876
4.323AsnGln: 4.323 ± 2.628
1.441AsnArg: 1.441 ± 0.876
5.764AsnSer: 5.764 ± 1.39
5.764AsnThr: 5.764 ± 3.504
4.323AsnVal: 4.323 ± 0.513
0.0AsnTrp: 0.0 ± 0.0
1.441AsnTyr: 1.441 ± 0.876
0.0AsnXaa: 0.0 ± 0.0
Pro
8.646ProAla: 8.646 ± 1.027
1.441ProCys: 1.441 ± 1.239
5.764ProAsp: 5.764 ± 0.725
1.441ProGlu: 1.441 ± 0.876
0.0ProPhe: 0.0 ± 0.0
2.882ProGly: 2.882 ± 2.478
1.441ProHis: 1.441 ± 1.239
4.323ProIle: 4.323 ± 0.513
2.882ProLys: 2.882 ± 1.752
4.323ProLeu: 4.323 ± 0.513
1.441ProMet: 1.441 ± 0.567
1.441ProAsn: 1.441 ± 0.876
1.441ProPro: 1.441 ± 1.239
1.441ProGln: 1.441 ± 1.239
1.441ProArg: 1.441 ± 1.239
0.0ProSer: 0.0 ± 0.0
1.441ProThr: 1.441 ± 1.239
1.441ProVal: 1.441 ± 0.876
1.441ProTrp: 1.441 ± 0.876
2.882ProTyr: 2.882 ± 0.363
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.441GlnCys: 1.441 ± 1.239
1.441GlnAsp: 1.441 ± 1.239
0.0GlnGlu: 0.0 ± 0.0
5.764GlnPhe: 5.764 ± 1.39
5.764GlnGly: 5.764 ± 1.39
2.882GlnHis: 2.882 ± 2.478
4.323GlnIle: 4.323 ± 1.601
0.0GlnLys: 0.0 ± 0.0
0.0GlnLeu: 0.0 ± 0.0
1.441GlnMet: 1.441 ± 0.876
1.441GlnAsn: 1.441 ± 0.876
0.0GlnPro: 0.0 ± 0.0
1.441GlnGln: 1.441 ± 1.239
0.0GlnArg: 0.0 ± 0.0
2.882GlnSer: 2.882 ± 0.363
2.882GlnThr: 2.882 ± 1.752
1.441GlnVal: 1.441 ± 1.239
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.441ArgAla: 1.441 ± 1.239
0.0ArgCys: 0.0 ± 0.0
2.882ArgAsp: 2.882 ± 1.752
4.323ArgGlu: 4.323 ± 0.513
1.441ArgPhe: 1.441 ± 0.876
4.323ArgGly: 4.323 ± 3.716
0.0ArgHis: 0.0 ± 0.0
1.441ArgIle: 1.441 ± 1.239
2.882ArgLys: 2.882 ± 1.752
7.205ArgLeu: 7.205 ± 0.151
0.0ArgMet: 0.0 ± 0.0
1.441ArgAsn: 1.441 ± 1.239
0.0ArgPro: 0.0 ± 0.0
1.441ArgGln: 1.441 ± 1.239
4.323ArgArg: 4.323 ± 3.716
5.764ArgSer: 5.764 ± 2.84
5.764ArgThr: 5.764 ± 2.84
5.764ArgVal: 5.764 ± 2.84
1.441ArgTrp: 1.441 ± 1.239
2.882ArgTyr: 2.882 ± 0.363
0.0ArgXaa: 0.0 ± 0.0
Ser
7.205SerAla: 7.205 ± 0.151
1.441SerCys: 1.441 ± 0.876
2.882SerAsp: 2.882 ± 0.363
2.882SerGlu: 2.882 ± 0.363
0.0SerPhe: 0.0 ± 0.0
5.764SerGly: 5.764 ± 0.725
4.323SerHis: 4.323 ± 1.601
2.882SerIle: 2.882 ± 1.752
4.323SerLys: 4.323 ± 0.513
5.764SerLeu: 5.764 ± 4.955
1.441SerMet: 1.441 ± 1.239
7.205SerAsn: 7.205 ± 0.151
2.882SerPro: 2.882 ± 0.363
4.323SerGln: 4.323 ± 0.513
7.205SerArg: 7.205 ± 4.079
10.086SerSer: 10.086 ± 0.212
8.646SerThr: 8.646 ± 1.027
11.527SerVal: 11.527 ± 1.451
1.441SerTrp: 1.441 ± 0.876
7.205SerTyr: 7.205 ± 2.266
0.0SerXaa: 0.0 ± 0.0
Thr
7.205ThrAla: 7.205 ± 2.266
0.0ThrCys: 0.0 ± 0.0
1.441ThrAsp: 1.441 ± 0.876
4.323ThrGlu: 4.323 ± 0.513
1.441ThrPhe: 1.441 ± 0.876
7.205ThrGly: 7.205 ± 0.151
0.0ThrHis: 0.0 ± 0.0
4.323ThrIle: 4.323 ± 0.513
7.205ThrLys: 7.205 ± 4.079
2.882ThrLeu: 2.882 ± 0.363
1.441ThrMet: 1.441 ± 0.876
4.323ThrAsn: 4.323 ± 2.628
1.441ThrPro: 1.441 ± 1.239
0.0ThrGln: 0.0 ± 0.0
5.764ThrArg: 5.764 ± 0.725
10.086ThrSer: 10.086 ± 0.212
4.323ThrThr: 4.323 ± 2.628
4.323ThrVal: 4.323 ± 2.628
0.0ThrTrp: 0.0 ± 0.0
1.441ThrTyr: 1.441 ± 0.876
0.0ThrXaa: 0.0 ± 0.0
Val
4.323ValAla: 4.323 ± 0.513
2.882ValCys: 2.882 ± 1.752
4.323ValAsp: 4.323 ± 3.716
0.0ValGlu: 0.0 ± 0.0
4.323ValPhe: 4.323 ± 0.513
5.764ValGly: 5.764 ± 3.504
2.882ValHis: 2.882 ± 1.752
1.441ValIle: 1.441 ± 1.239
2.882ValLys: 2.882 ± 0.363
4.323ValLeu: 4.323 ± 0.513
1.441ValMet: 1.441 ± 0.656
2.882ValAsn: 2.882 ± 1.752
2.882ValPro: 2.882 ± 0.363
0.0ValGln: 0.0 ± 0.0
4.323ValArg: 4.323 ± 1.601
4.323ValSer: 4.323 ± 0.513
2.882ValThr: 2.882 ± 0.363
5.764ValVal: 5.764 ± 1.39
5.764ValTrp: 5.764 ± 2.84
2.882ValTyr: 2.882 ± 1.752
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.441TrpCys: 1.441 ± 1.239
0.0TrpAsp: 0.0 ± 0.0
1.441TrpGlu: 1.441 ± 1.239
2.882TrpPhe: 2.882 ± 0.363
1.441TrpGly: 1.441 ± 1.239
0.0TrpHis: 0.0 ± 0.0
1.441TrpIle: 1.441 ± 1.239
5.764TrpLys: 5.764 ± 1.39
2.882TrpLeu: 2.882 ± 0.363
1.441TrpMet: 1.441 ± 1.239
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.441TrpGln: 1.441 ± 1.239
0.0TrpArg: 0.0 ± 0.0
1.441TrpSer: 1.441 ± 1.239
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.441TrpTyr: 1.441 ± 1.239
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.441TyrAla: 1.441 ± 0.876
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
1.441TyrGlu: 1.441 ± 1.239
0.0TyrPhe: 0.0 ± 0.0
2.882TyrGly: 2.882 ± 1.752
1.441TyrHis: 1.441 ± 0.876
4.323TyrIle: 4.323 ± 2.628
5.764TyrLys: 5.764 ± 1.39
4.323TyrLeu: 4.323 ± 1.601
1.441TyrMet: 1.441 ± 0.876
4.323TyrAsn: 4.323 ± 2.628
4.323TyrPro: 4.323 ± 1.601
1.441TyrGln: 1.441 ± 0.876
4.323TyrArg: 4.323 ± 1.601
4.323TyrSer: 4.323 ± 0.513
1.441TyrThr: 1.441 ± 0.876
2.882TyrVal: 2.882 ± 0.363
1.441TyrTrp: 1.441 ± 1.239
2.882TyrTyr: 2.882 ± 0.363
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (695 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski