Amino acid dipepetide frequency for Lettuce infectious yellows virus (isolate United States/92) (LIYV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.511AlaAla: 1.511 ± 0.675
0.604AlaCys: 0.604 ± 0.187
2.568AlaAsp: 2.568 ± 0.753
1.964AlaGlu: 1.964 ± 0.42
0.906AlaPhe: 0.906 ± 0.238
2.568AlaGly: 2.568 ± 0.554
0.0AlaHis: 0.0 ± 0.0
3.022AlaIle: 3.022 ± 0.475
5.439AlaLys: 5.439 ± 0.67
4.079AlaLeu: 4.079 ± 0.71
1.209AlaMet: 1.209 ± 0.566
2.266AlaAsn: 2.266 ± 0.491
0.604AlaPro: 0.604 ± 0.304
1.209AlaGln: 1.209 ± 0.431
2.266AlaArg: 2.266 ± 0.496
2.417AlaSer: 2.417 ± 0.73
2.115AlaThr: 2.115 ± 0.364
3.626AlaVal: 3.626 ± 0.482
0.302AlaTrp: 0.302 ± 0.114
1.964AlaTyr: 1.964 ± 0.427
0.0AlaXaa: 0.0 ± 0.0
Cys
0.755CysAla: 0.755 ± 0.239
0.151CysCys: 0.151 ± 0.116
1.36CysAsp: 1.36 ± 0.503
0.906CysGlu: 0.906 ± 0.396
1.662CysPhe: 1.662 ± 0.279
1.058CysGly: 1.058 ± 0.374
0.302CysHis: 0.302 ± 0.114
1.511CysIle: 1.511 ± 0.261
1.511CysLys: 1.511 ± 0.353
1.964CysLeu: 1.964 ± 0.433
0.302CysMet: 0.302 ± 0.183
2.266CysAsn: 2.266 ± 0.346
0.302CysPro: 0.302 ± 0.114
0.302CysGln: 0.302 ± 0.114
1.511CysArg: 1.511 ± 0.372
1.209CysSer: 1.209 ± 0.293
1.36CysThr: 1.36 ± 0.429
0.906CysVal: 0.906 ± 0.42
0.302CysTrp: 0.302 ± 0.114
1.662CysTyr: 1.662 ± 0.285
0.0CysXaa: 0.0 ± 0.0
Asp
2.115AspAla: 2.115 ± 0.433
1.36AspCys: 1.36 ± 0.29
4.079AspAsp: 4.079 ± 0.571
3.626AspGlu: 3.626 ± 0.901
5.741AspPhe: 5.741 ± 0.443
2.568AspGly: 2.568 ± 0.357
0.604AspHis: 0.604 ± 0.254
5.59AspIle: 5.59 ± 0.702
4.986AspLys: 4.986 ± 1.435
6.496AspLeu: 6.496 ± 0.667
1.209AspMet: 1.209 ± 0.42
4.683AspAsn: 4.683 ± 0.378
1.36AspPro: 1.36 ± 0.354
1.511AspGln: 1.511 ± 0.2
3.626AspArg: 3.626 ± 0.443
5.137AspSer: 5.137 ± 1.093
3.777AspThr: 3.777 ± 0.769
4.23AspVal: 4.23 ± 0.563
0.453AspTrp: 0.453 ± 0.134
3.022AspTyr: 3.022 ± 0.879
0.0AspXaa: 0.0 ± 0.0
Glu
2.871GluAla: 2.871 ± 0.354
1.662GluCys: 1.662 ± 0.144
4.986GluAsp: 4.986 ± 0.77
2.417GluGlu: 2.417 ± 0.288
3.777GluPhe: 3.777 ± 0.503
2.417GluGly: 2.417 ± 0.615
0.453GluHis: 0.453 ± 0.188
4.835GluIle: 4.835 ± 0.488
5.137GluLys: 5.137 ± 0.798
4.532GluLeu: 4.532 ± 0.596
2.115GluMet: 2.115 ± 0.328
2.115GluAsn: 2.115 ± 0.523
0.755GluPro: 0.755 ± 0.292
1.662GluGln: 1.662 ± 0.317
3.324GluArg: 3.324 ± 0.414
3.324GluSer: 3.324 ± 0.509
2.871GluThr: 2.871 ± 0.286
4.381GluVal: 4.381 ± 0.956
1.662GluTrp: 1.662 ± 0.398
2.266GluTyr: 2.266 ± 0.443
0.0GluXaa: 0.0 ± 0.0
Phe
2.719PheAla: 2.719 ± 0.285
1.058PheCys: 1.058 ± 0.36
2.417PheAsp: 2.417 ± 0.439
2.719PheGlu: 2.719 ± 0.675
1.662PhePhe: 1.662 ± 0.255
2.568PheGly: 2.568 ± 0.552
0.302PheHis: 0.302 ± 0.396
4.532PheIle: 4.532 ± 0.601
5.288PheLys: 5.288 ± 0.722
4.381PheLeu: 4.381 ± 0.565
1.511PheMet: 1.511 ± 0.473
3.928PheAsn: 3.928 ± 0.36
1.813PhePro: 1.813 ± 0.755
1.209PheGln: 1.209 ± 0.374
2.871PheArg: 2.871 ± 0.582
6.345PheSer: 6.345 ± 1.531
2.417PheThr: 2.417 ± 0.581
3.324PheVal: 3.324 ± 0.403
0.151PheTrp: 0.151 ± 0.198
2.115PheTyr: 2.115 ± 0.364
0.0PheXaa: 0.0 ± 0.0
Gly
1.209GlyAla: 1.209 ± 0.328
1.662GlyCys: 1.662 ± 0.31
3.626GlyAsp: 3.626 ± 0.55
2.719GlyGlu: 2.719 ± 0.376
2.719GlyPhe: 2.719 ± 0.803
4.532GlyGly: 4.532 ± 0.876
0.906GlyHis: 0.906 ± 0.342
3.173GlyIle: 3.173 ± 0.496
4.986GlyLys: 4.986 ± 0.775
2.568GlyLeu: 2.568 ± 0.613
1.058GlyMet: 1.058 ± 0.427
2.719GlyAsn: 2.719 ± 0.686
0.0GlyPro: 0.0 ± 0.0
0.453GlyGln: 0.453 ± 0.155
1.662GlyArg: 1.662 ± 0.473
4.23GlySer: 4.23 ± 0.592
1.511GlyThr: 1.511 ± 0.304
3.777GlyVal: 3.777 ± 0.596
0.453GlyTrp: 0.453 ± 0.148
1.662GlyTyr: 1.662 ± 0.263
0.0GlyXaa: 0.0 ± 0.0
His
0.604HisAla: 0.604 ± 0.228
0.906HisCys: 0.906 ± 0.345
0.453HisAsp: 0.453 ± 0.437
0.604HisGlu: 0.604 ± 0.206
1.511HisPhe: 1.511 ± 0.476
1.209HisGly: 1.209 ± 0.311
0.302HisHis: 0.302 ± 0.114
1.511HisIle: 1.511 ± 0.569
0.755HisLys: 0.755 ± 0.203
0.755HisLeu: 0.755 ± 0.301
0.0HisMet: 0.0 ± 0.0
1.209HisAsn: 1.209 ± 0.214
1.511HisPro: 1.511 ± 0.195
0.302HisGln: 0.302 ± 0.339
0.453HisArg: 0.453 ± 0.348
1.058HisSer: 1.058 ± 0.306
1.511HisThr: 1.511 ± 0.212
0.906HisVal: 0.906 ± 0.241
0.302HisTrp: 0.302 ± 0.114
2.266HisTyr: 2.266 ± 0.455
0.0HisXaa: 0.0 ± 0.0
Ile
2.871IleAla: 2.871 ± 0.363
1.813IleCys: 1.813 ± 0.449
6.648IleAsp: 6.648 ± 1.003
5.741IleGlu: 5.741 ± 0.491
4.079IlePhe: 4.079 ± 0.426
1.813IleGly: 1.813 ± 0.611
0.755IleHis: 0.755 ± 0.301
7.101IleIle: 7.101 ± 0.988
6.496IleLys: 6.496 ± 0.664
5.892IleLeu: 5.892 ± 0.574
1.662IleMet: 1.662 ± 0.358
6.043IleAsn: 6.043 ± 1.31
4.079IlePro: 4.079 ± 0.99
1.964IleGln: 1.964 ± 0.428
3.928IleArg: 3.928 ± 0.327
5.288IleSer: 5.288 ± 1.154
3.324IleThr: 3.324 ± 0.617
4.683IleVal: 4.683 ± 1.278
0.302IleTrp: 0.302 ± 0.114
3.022IleTyr: 3.022 ± 0.49
0.0IleXaa: 0.0 ± 0.0
Lys
3.324LysAla: 3.324 ± 0.604
1.209LysCys: 1.209 ± 0.235
4.986LysAsp: 4.986 ± 0.741
6.496LysGlu: 6.496 ± 0.869
4.986LysPhe: 4.986 ± 0.492
3.324LysGly: 3.324 ± 0.771
1.058LysHis: 1.058 ± 0.39
6.345LysIle: 6.345 ± 1.078
5.439LysLys: 5.439 ± 0.572
8.309LysLeu: 8.309 ± 0.516
3.173LysMet: 3.173 ± 0.571
4.532LysAsn: 4.532 ± 0.677
3.777LysPro: 3.777 ± 0.781
2.417LysGln: 2.417 ± 0.625
3.324LysArg: 3.324 ± 0.488
6.345LysSer: 6.345 ± 0.832
5.892LysThr: 5.892 ± 0.756
4.23LysVal: 4.23 ± 0.548
0.755LysTrp: 0.755 ± 0.196
5.288LysTyr: 5.288 ± 0.649
0.0LysXaa: 0.0 ± 0.0
Leu
3.928LeuAla: 3.928 ± 1.324
1.36LeuCys: 1.36 ± 0.397
6.799LeuAsp: 6.799 ± 0.969
6.043LeuGlu: 6.043 ± 0.559
3.475LeuPhe: 3.475 ± 0.347
3.626LeuGly: 3.626 ± 0.584
2.115LeuHis: 2.115 ± 0.375
5.741LeuIle: 5.741 ± 0.966
9.82LeuLys: 9.82 ± 0.76
6.799LeuLeu: 6.799 ± 1.138
2.266LeuMet: 2.266 ± 0.388
6.799LeuAsn: 6.799 ± 1.018
1.662LeuPro: 1.662 ± 0.496
1.662LeuGln: 1.662 ± 0.257
4.381LeuArg: 4.381 ± 0.378
8.309LeuSer: 8.309 ± 0.369
5.892LeuThr: 5.892 ± 0.612
3.626LeuVal: 3.626 ± 0.752
0.755LeuTrp: 0.755 ± 0.18
3.626LeuTyr: 3.626 ± 0.707
0.0LeuXaa: 0.0 ± 0.0
Met
0.906MetAla: 0.906 ± 0.296
0.0MetCys: 0.0 ± 0.0
1.36MetAsp: 1.36 ± 0.464
0.906MetGlu: 0.906 ± 0.333
0.604MetPhe: 0.604 ± 0.328
0.604MetGly: 0.604 ± 0.216
0.604MetHis: 0.604 ± 0.228
1.209MetIle: 1.209 ± 0.318
0.302MetLys: 0.302 ± 0.192
2.115MetLeu: 2.115 ± 0.376
0.906MetMet: 0.906 ± 0.259
1.813MetAsn: 1.813 ± 0.518
0.453MetPro: 0.453 ± 0.134
0.906MetGln: 0.906 ± 0.376
1.36MetArg: 1.36 ± 0.725
2.417MetSer: 2.417 ± 0.495
1.511MetThr: 1.511 ± 0.395
1.964MetVal: 1.964 ± 0.272
0.0MetTrp: 0.0 ± 0.0
0.906MetTyr: 0.906 ± 0.237
0.0MetXaa: 0.0 ± 0.0
Asn
3.626AsnAla: 3.626 ± 0.377
0.755AsnCys: 0.755 ± 0.202
4.835AsnAsp: 4.835 ± 1.399
2.417AsnGlu: 2.417 ± 0.376
4.532AsnPhe: 4.532 ± 0.621
2.417AsnGly: 2.417 ± 0.517
1.209AsnHis: 1.209 ± 0.274
7.705AsnIle: 7.705 ± 1.157
5.741AsnLys: 5.741 ± 0.888
8.007AsnLeu: 8.007 ± 0.913
0.0AsnMet: 0.0 ± 0.0
5.439AsnAsn: 5.439 ± 1.298
1.662AsnPro: 1.662 ± 0.29
1.209AsnGln: 1.209 ± 0.275
3.173AsnArg: 3.173 ± 0.518
4.381AsnSer: 4.381 ± 0.779
3.928AsnThr: 3.928 ± 0.551
3.475AsnVal: 3.475 ± 0.562
0.302AsnTrp: 0.302 ± 0.114
2.568AsnTyr: 2.568 ± 0.867
0.0AsnXaa: 0.0 ± 0.0
Pro
1.964ProAla: 1.964 ± 0.359
0.453ProCys: 0.453 ± 0.263
1.209ProAsp: 1.209 ± 0.262
2.266ProGlu: 2.266 ± 0.286
1.36ProPhe: 1.36 ± 0.151
1.813ProGly: 1.813 ± 0.439
1.058ProHis: 1.058 ± 0.263
2.266ProIle: 2.266 ± 0.535
2.266ProLys: 2.266 ± 0.414
1.813ProLeu: 1.813 ± 0.338
0.604ProMet: 0.604 ± 0.209
1.662ProAsn: 1.662 ± 0.51
1.511ProPro: 1.511 ± 0.326
0.453ProGln: 0.453 ± 0.491
0.906ProArg: 0.906 ± 0.182
1.209ProSer: 1.209 ± 0.275
1.662ProThr: 1.662 ± 0.276
2.115ProVal: 2.115 ± 0.463
0.604ProTrp: 0.604 ± 0.228
2.115ProTyr: 2.115 ± 0.536
0.0ProXaa: 0.0 ± 0.0
Gln
0.604GlnAla: 0.604 ± 0.52
0.755GlnCys: 0.755 ± 0.228
2.266GlnAsp: 2.266 ± 0.275
1.058GlnGlu: 1.058 ± 0.515
1.058GlnPhe: 1.058 ± 0.287
1.511GlnGly: 1.511 ± 0.452
0.453GlnHis: 0.453 ± 0.366
1.209GlnIle: 1.209 ± 0.299
0.604GlnLys: 0.604 ± 0.228
2.115GlnLeu: 2.115 ± 0.611
0.453GlnMet: 0.453 ± 0.188
1.058GlnAsn: 1.058 ± 0.33
0.755GlnPro: 0.755 ± 0.296
0.302GlnGln: 0.302 ± 0.179
3.173GlnArg: 3.173 ± 0.622
2.115GlnSer: 2.115 ± 0.503
1.813GlnThr: 1.813 ± 0.447
1.36GlnVal: 1.36 ± 0.347
0.0GlnTrp: 0.0 ± 0.0
0.906GlnTyr: 0.906 ± 0.247
0.0GlnXaa: 0.0 ± 0.0
Arg
3.324ArgAla: 3.324 ± 1.144
1.662ArgCys: 1.662 ± 0.461
4.079ArgAsp: 4.079 ± 0.486
2.871ArgGlu: 2.871 ± 0.692
2.266ArgPhe: 2.266 ± 0.459
1.36ArgGly: 1.36 ± 0.377
1.511ArgHis: 1.511 ± 0.235
3.324ArgIle: 3.324 ± 0.31
3.173ArgLys: 3.173 ± 0.601
5.892ArgLeu: 5.892 ± 0.782
1.058ArgMet: 1.058 ± 0.273
3.475ArgAsn: 3.475 ± 0.977
1.813ArgPro: 1.813 ± 0.402
0.906ArgGln: 0.906 ± 0.24
2.115ArgArg: 2.115 ± 0.495
5.439ArgSer: 5.439 ± 0.683
0.755ArgThr: 0.755 ± 0.295
3.626ArgVal: 3.626 ± 0.483
1.058ArgTrp: 1.058 ± 0.252
1.813ArgTyr: 1.813 ± 0.192
0.0ArgXaa: 0.0 ± 0.0
Ser
2.871SerAla: 2.871 ± 0.605
1.511SerCys: 1.511 ± 0.569
4.532SerAsp: 4.532 ± 0.462
3.777SerGlu: 3.777 ± 0.913
3.475SerPhe: 3.475 ± 1.014
2.719SerGly: 2.719 ± 0.779
2.115SerHis: 2.115 ± 0.386
6.194SerIle: 6.194 ± 0.458
8.309SerLys: 8.309 ± 0.71
6.194SerLeu: 6.194 ± 0.701
1.511SerMet: 1.511 ± 0.349
5.137SerAsn: 5.137 ± 0.559
2.266SerPro: 2.266 ± 0.512
1.813SerGln: 1.813 ± 0.248
4.683SerArg: 4.683 ± 0.413
5.137SerSer: 5.137 ± 0.546
3.324SerThr: 3.324 ± 0.693
5.892SerVal: 5.892 ± 0.959
0.906SerTrp: 0.906 ± 0.182
4.532SerTyr: 4.532 ± 0.584
0.0SerXaa: 0.0 ± 0.0
Thr
0.906ThrAla: 0.906 ± 0.397
1.511ThrCys: 1.511 ± 0.225
2.871ThrAsp: 2.871 ± 0.837
2.266ThrGlu: 2.266 ± 0.385
3.022ThrPhe: 3.022 ± 0.759
3.475ThrGly: 3.475 ± 0.49
2.115ThrHis: 2.115 ± 0.32
3.928ThrIle: 3.928 ± 0.503
5.137ThrLys: 5.137 ± 0.524
6.648ThrLeu: 6.648 ± 0.861
0.302ThrMet: 0.302 ± 0.288
3.626ThrAsn: 3.626 ± 0.49
1.662ThrPro: 1.662 ± 0.268
2.115ThrGln: 2.115 ± 0.338
2.266ThrArg: 2.266 ± 0.619
3.324ThrSer: 3.324 ± 0.966
3.475ThrThr: 3.475 ± 0.425
2.871ThrVal: 2.871 ± 0.505
0.302ThrTrp: 0.302 ± 0.232
3.022ThrTyr: 3.022 ± 0.665
0.0ThrXaa: 0.0 ± 0.0
Val
2.115ValAla: 2.115 ± 0.492
1.209ValCys: 1.209 ± 0.308
2.719ValAsp: 2.719 ± 0.646
5.59ValGlu: 5.59 ± 0.46
2.568ValPhe: 2.568 ± 0.644
3.777ValGly: 3.777 ± 0.787
0.604ValHis: 0.604 ± 0.228
3.626ValIle: 3.626 ± 0.691
6.043ValLys: 6.043 ± 0.848
4.23ValLeu: 4.23 ± 0.433
0.755ValMet: 0.755 ± 0.198
5.439ValAsn: 5.439 ± 0.658
1.36ValPro: 1.36 ± 0.403
1.662ValGln: 1.662 ± 0.357
3.475ValArg: 3.475 ± 0.585
6.043ValSer: 6.043 ± 1.165
4.079ValThr: 4.079 ± 0.658
5.137ValVal: 5.137 ± 0.256
0.453ValTrp: 0.453 ± 0.198
2.719ValTyr: 2.719 ± 0.777
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.302TrpCys: 0.302 ± 0.316
0.302TrpAsp: 0.302 ± 0.114
0.302TrpGlu: 0.302 ± 0.114
1.36TrpPhe: 1.36 ± 0.389
0.302TrpGly: 0.302 ± 0.114
0.151TrpHis: 0.151 ± 0.185
0.604TrpIle: 0.604 ± 0.164
0.604TrpLys: 0.604 ± 0.2
1.058TrpLeu: 1.058 ± 0.33
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.151TrpPro: 0.151 ± 0.175
0.0TrpGln: 0.0 ± 0.0
1.209TrpArg: 1.209 ± 0.456
0.302TrpSer: 0.302 ± 0.114
1.209TrpThr: 1.209 ± 0.33
1.058TrpVal: 1.058 ± 0.238
0.302TrpTrp: 0.302 ± 0.114
0.453TrpTyr: 0.453 ± 0.198
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.417TyrAla: 2.417 ± 0.29
1.36TyrCys: 1.36 ± 0.222
4.079TyrAsp: 4.079 ± 0.714
2.871TyrGlu: 2.871 ± 0.615
2.568TyrPhe: 2.568 ± 0.48
1.964TyrGly: 1.964 ± 0.284
1.511TyrHis: 1.511 ± 0.43
4.23TyrIle: 4.23 ± 0.51
3.173TyrLys: 3.173 ± 0.459
4.835TyrLeu: 4.835 ± 1.086
0.604TyrMet: 0.604 ± 0.452
3.173TyrAsn: 3.173 ± 0.49
1.813TyrPro: 1.813 ± 0.432
1.511TyrGln: 1.511 ± 0.485
1.813TyrArg: 1.813 ± 0.231
2.871TyrSer: 2.871 ± 0.393
2.417TyrThr: 2.417 ± 0.33
2.417TyrVal: 2.417 ± 0.577
0.302TyrTrp: 0.302 ± 0.114
2.266TyrTyr: 2.266 ± 0.495
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (6620 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski