Amino acid dipepetide frequency for Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.923AlaAla: 6.923 ± 2.313
1.117AlaCys: 1.117 ± 0.489
5.36AlaAsp: 5.36 ± 0.467
3.796AlaGlu: 3.796 ± 0.915
2.68AlaPhe: 2.68 ± 0.957
5.36AlaGly: 5.36 ± 1.826
1.563AlaHis: 1.563 ± 0.554
2.456AlaIle: 2.456 ± 0.555
2.903AlaLys: 2.903 ± 0.876
5.583AlaLeu: 5.583 ± 1.863
2.456AlaMet: 2.456 ± 0.795
4.243AlaAsn: 4.243 ± 1.232
2.903AlaPro: 2.903 ± 0.68
2.456AlaGln: 2.456 ± 0.584
3.573AlaArg: 3.573 ± 0.943
4.466AlaSer: 4.466 ± 0.859
3.35AlaThr: 3.35 ± 0.88
5.136AlaVal: 5.136 ± 0.88
0.893AlaTrp: 0.893 ± 0.57
2.68AlaTyr: 2.68 ± 0.636
0.0AlaXaa: 0.0 ± 0.0
Cys
1.117CysAla: 1.117 ± 0.562
0.67CysCys: 0.67 ± 0.837
1.787CysAsp: 1.787 ± 1.193
1.34CysGlu: 1.34 ± 0.634
1.34CysPhe: 1.34 ± 0.751
2.68CysGly: 2.68 ± 1.048
0.67CysHis: 0.67 ± 0.499
0.223CysIle: 0.223 ± 0.37
0.67CysLys: 0.67 ± 0.389
2.01CysLeu: 2.01 ± 0.797
0.67CysMet: 0.67 ± 0.358
1.117CysAsn: 1.117 ± 0.392
0.223CysPro: 0.223 ± 0.143
0.67CysGln: 0.67 ± 0.463
1.563CysArg: 1.563 ± 0.823
0.893CysSer: 0.893 ± 0.831
0.893CysThr: 0.893 ± 0.76
2.68CysVal: 2.68 ± 1.049
0.223CysTrp: 0.223 ± 0.336
1.563CysTyr: 1.563 ± 0.842
0.0CysXaa: 0.0 ± 0.0
Asp
3.35AspAla: 3.35 ± 0.987
1.34AspCys: 1.34 ± 0.727
5.136AspAsp: 5.136 ± 0.953
2.68AspGlu: 2.68 ± 0.689
3.126AspPhe: 3.126 ± 1.175
3.796AspGly: 3.796 ± 1.121
0.67AspHis: 0.67 ± 0.637
3.796AspIle: 3.796 ± 1.344
2.68AspLys: 2.68 ± 0.87
5.36AspLeu: 5.36 ± 0.818
2.456AspMet: 2.456 ± 0.46
4.913AspAsn: 4.913 ± 1.452
2.903AspPro: 2.903 ± 0.58
0.67AspGln: 0.67 ± 0.409
2.903AspArg: 2.903 ± 1.266
5.36AspSer: 5.36 ± 0.832
2.903AspThr: 2.903 ± 0.931
7.369AspVal: 7.369 ± 1.915
2.233AspTrp: 2.233 ± 0.938
2.233AspTyr: 2.233 ± 0.564
0.0AspXaa: 0.0 ± 0.0
Glu
2.903GluAla: 2.903 ± 0.983
1.34GluCys: 1.34 ± 0.54
2.68GluAsp: 2.68 ± 1.246
2.233GluGlu: 2.233 ± 0.802
4.02GluPhe: 4.02 ± 0.971
3.35GluGly: 3.35 ± 0.759
1.34GluHis: 1.34 ± 0.624
1.34GluIle: 1.34 ± 0.551
3.35GluLys: 3.35 ± 1.577
6.253GluLeu: 6.253 ± 0.977
0.447GluMet: 0.447 ± 0.285
1.563GluAsn: 1.563 ± 0.527
0.893GluPro: 0.893 ± 0.57
1.563GluGln: 1.563 ± 0.581
3.35GluArg: 3.35 ± 1.027
4.913GluSer: 4.913 ± 0.656
1.787GluThr: 1.787 ± 0.381
5.36GluVal: 5.36 ± 0.82
0.223GluTrp: 0.223 ± 0.235
1.563GluTyr: 1.563 ± 0.843
0.0GluXaa: 0.0 ± 0.0
Phe
3.126PheAla: 3.126 ± 0.777
2.233PheCys: 2.233 ± 0.704
2.233PheAsp: 2.233 ± 0.588
2.903PheGlu: 2.903 ± 0.901
1.34PhePhe: 1.34 ± 0.586
2.68PheGly: 2.68 ± 1.047
1.117PheHis: 1.117 ± 0.518
2.233PheIle: 2.233 ± 1.157
1.563PheLys: 1.563 ± 0.61
2.903PheLeu: 2.903 ± 0.774
2.233PheMet: 2.233 ± 0.602
2.233PheAsn: 2.233 ± 1.302
2.01PhePro: 2.01 ± 0.434
0.893PheGln: 0.893 ± 0.386
3.573PheArg: 3.573 ± 1.428
3.573PheSer: 3.573 ± 1.2
2.233PheThr: 2.233 ± 0.925
4.02PheVal: 4.02 ± 0.693
0.893PheTrp: 0.893 ± 0.515
1.563PheTyr: 1.563 ± 0.444
0.0PheXaa: 0.0 ± 0.0
Gly
5.136GlyAla: 5.136 ± 1.234
2.01GlyCys: 2.01 ± 1.045
4.243GlyAsp: 4.243 ± 1.188
3.126GlyGlu: 3.126 ± 0.65
2.233GlyPhe: 2.233 ± 0.764
4.913GlyGly: 4.913 ± 2.273
2.01GlyHis: 2.01 ± 0.695
2.903GlyIle: 2.903 ± 0.673
4.69GlyLys: 4.69 ± 1.903
4.466GlyLeu: 4.466 ± 2.176
2.456GlyMet: 2.456 ± 0.554
2.903GlyAsn: 2.903 ± 0.891
2.01GlyPro: 2.01 ± 0.398
2.01GlyGln: 2.01 ± 0.473
3.126GlyArg: 3.126 ± 1.29
5.36GlySer: 5.36 ± 1.218
2.233GlyThr: 2.233 ± 0.509
7.369GlyVal: 7.369 ± 1.35
1.787GlyTrp: 1.787 ± 0.977
2.01GlyTyr: 2.01 ± 0.66
0.0GlyXaa: 0.0 ± 0.0
His
1.563HisAla: 1.563 ± 0.654
0.67HisCys: 0.67 ± 0.569
1.787HisAsp: 1.787 ± 1.075
0.67HisGlu: 0.67 ± 0.29
1.787HisPhe: 1.787 ± 0.589
1.34HisGly: 1.34 ± 0.646
0.893HisHis: 0.893 ± 0.467
1.563HisIle: 1.563 ± 0.406
0.893HisLys: 0.893 ± 0.546
1.787HisLeu: 1.787 ± 0.742
1.34HisMet: 1.34 ± 0.439
0.893HisAsn: 0.893 ± 0.995
0.893HisPro: 0.893 ± 0.417
0.447HisGln: 0.447 ± 0.316
1.787HisArg: 1.787 ± 0.82
1.34HisSer: 1.34 ± 0.623
1.117HisThr: 1.117 ± 0.366
1.787HisVal: 1.787 ± 0.867
0.0HisTrp: 0.0 ± 0.0
1.117HisTyr: 1.117 ± 0.562
0.0HisXaa: 0.0 ± 0.0
Ile
2.456IleAla: 2.456 ± 0.947
1.787IleCys: 1.787 ± 1.06
2.01IleAsp: 2.01 ± 0.893
2.903IleGlu: 2.903 ± 0.646
1.117IlePhe: 1.117 ± 0.507
2.233IleGly: 2.233 ± 0.766
0.67IleHis: 0.67 ± 0.409
2.233IleIle: 2.233 ± 0.603
3.796IleLys: 3.796 ± 0.558
4.243IleLeu: 4.243 ± 1.258
1.787IleMet: 1.787 ± 0.768
2.456IleAsn: 2.456 ± 0.655
1.34IlePro: 1.34 ± 0.582
0.893IleGln: 0.893 ± 0.472
1.787IleArg: 1.787 ± 0.485
2.903IleSer: 2.903 ± 1.34
2.01IleThr: 2.01 ± 0.736
3.573IleVal: 3.573 ± 1.549
0.0IleTrp: 0.0 ± 0.0
1.787IleTyr: 1.787 ± 1.265
0.0IleXaa: 0.0 ± 0.0
Lys
3.573LysAla: 3.573 ± 0.8
0.67LysCys: 0.67 ± 0.706
2.68LysAsp: 2.68 ± 0.583
3.35LysGlu: 3.35 ± 0.749
2.903LysPhe: 2.903 ± 0.639
2.903LysGly: 2.903 ± 1.161
2.01LysHis: 2.01 ± 0.832
2.233LysIle: 2.233 ± 0.993
3.126LysLys: 3.126 ± 1.325
5.806LysLeu: 5.806 ± 1.21
1.34LysMet: 1.34 ± 0.84
2.01LysAsn: 2.01 ± 1.134
1.34LysPro: 1.34 ± 0.654
1.563LysGln: 1.563 ± 0.482
2.903LysArg: 2.903 ± 0.766
2.903LysSer: 2.903 ± 1.443
3.573LysThr: 3.573 ± 0.764
3.35LysVal: 3.35 ± 0.879
0.223LysTrp: 0.223 ± 0.307
2.456LysTyr: 2.456 ± 0.857
0.0LysXaa: 0.0 ± 0.0
Leu
6.699LeuAla: 6.699 ± 2.515
2.233LeuCys: 2.233 ± 1.942
5.583LeuAsp: 5.583 ± 1.379
5.136LeuGlu: 5.136 ± 1.294
3.796LeuPhe: 3.796 ± 1.13
4.466LeuGly: 4.466 ± 0.945
2.233LeuHis: 2.233 ± 0.804
3.796LeuIle: 3.796 ± 0.524
5.36LeuLys: 5.36 ± 1.526
9.379LeuLeu: 9.379 ± 1.062
2.456LeuMet: 2.456 ± 0.877
4.466LeuAsn: 4.466 ± 1.585
4.913LeuPro: 4.913 ± 0.618
2.01LeuGln: 2.01 ± 0.686
5.36LeuArg: 5.36 ± 1.341
7.146LeuSer: 7.146 ± 1.787
5.36LeuThr: 5.36 ± 1.046
7.816LeuVal: 7.816 ± 1.804
1.563LeuTrp: 1.563 ± 0.54
2.68LeuTyr: 2.68 ± 0.984
0.0LeuXaa: 0.0 ± 0.0
Met
2.233MetAla: 2.233 ± 0.581
0.447MetCys: 0.447 ± 0.283
1.787MetAsp: 1.787 ± 0.47
0.893MetGlu: 0.893 ± 0.57
0.893MetPhe: 0.893 ± 0.386
1.34MetGly: 1.34 ± 0.546
0.223MetHis: 0.223 ± 0.143
0.893MetIle: 0.893 ± 0.442
0.893MetLys: 0.893 ± 0.443
2.903MetLeu: 2.903 ± 0.513
0.67MetMet: 0.67 ± 0.428
0.893MetAsn: 0.893 ± 0.57
1.34MetPro: 1.34 ± 0.463
0.67MetGln: 0.67 ± 0.361
0.893MetArg: 0.893 ± 0.329
4.466MetSer: 4.466 ± 0.97
2.233MetThr: 2.233 ± 1.945
3.573MetVal: 3.573 ± 0.99
0.447MetTrp: 0.447 ± 0.442
1.117MetTyr: 1.117 ± 0.408
0.0MetXaa: 0.0 ± 0.0
Asn
2.903AsnAla: 2.903 ± 0.488
1.34AsnCys: 1.34 ± 0.526
3.126AsnAsp: 3.126 ± 1.292
2.233AsnGlu: 2.233 ± 0.624
2.68AsnPhe: 2.68 ± 0.822
3.573AsnGly: 3.573 ± 1.091
1.787AsnHis: 1.787 ± 0.606
3.126AsnIle: 3.126 ± 0.732
2.456AsnLys: 2.456 ± 0.772
5.36AsnLeu: 5.36 ± 1.005
1.34AsnMet: 1.34 ± 0.576
2.68AsnAsn: 2.68 ± 1.196
1.787AsnPro: 1.787 ± 0.565
0.67AsnGln: 0.67 ± 0.428
1.117AsnArg: 1.117 ± 0.38
3.573AsnSer: 3.573 ± 1.378
2.456AsnThr: 2.456 ± 1.003
5.136AsnVal: 5.136 ± 1.303
0.0AsnTrp: 0.0 ± 0.0
1.34AsnTyr: 1.34 ± 0.617
0.0AsnXaa: 0.0 ± 0.0
Pro
2.456ProAla: 2.456 ± 0.742
0.447ProCys: 0.447 ± 0.555
2.233ProAsp: 2.233 ± 0.511
2.903ProGlu: 2.903 ± 0.645
2.233ProPhe: 2.233 ± 0.858
2.68ProGly: 2.68 ± 0.895
0.447ProHis: 0.447 ± 0.2
3.796ProIle: 3.796 ± 1.51
0.67ProLys: 0.67 ± 0.499
2.903ProLeu: 2.903 ± 0.759
0.893ProMet: 0.893 ± 0.368
2.01ProAsn: 2.01 ± 0.683
2.903ProPro: 2.903 ± 1.542
0.67ProGln: 0.67 ± 0.381
1.117ProArg: 1.117 ± 0.727
2.68ProSer: 2.68 ± 0.857
1.34ProThr: 1.34 ± 0.455
4.02ProVal: 4.02 ± 1.013
0.447ProTrp: 0.447 ± 0.442
1.787ProTyr: 1.787 ± 0.787
0.0ProXaa: 0.0 ± 0.0
Gln
1.787GlnAla: 1.787 ± 0.517
0.67GlnCys: 0.67 ± 0.409
0.893GlnAsp: 0.893 ± 0.417
1.787GlnGlu: 1.787 ± 0.559
1.34GlnPhe: 1.34 ± 0.613
2.01GlnGly: 2.01 ± 0.524
0.0GlnHis: 0.0 ± 0.0
0.893GlnIle: 0.893 ± 0.57
1.787GlnLys: 1.787 ± 0.633
2.456GlnLeu: 2.456 ± 0.587
0.893GlnMet: 0.893 ± 0.556
0.893GlnAsn: 0.893 ± 0.713
0.447GlnPro: 0.447 ± 0.2
0.893GlnGln: 0.893 ± 0.657
2.01GlnArg: 2.01 ± 0.762
2.233GlnSer: 2.233 ± 0.606
2.01GlnThr: 2.01 ± 0.524
2.01GlnVal: 2.01 ± 0.66
0.447GlnTrp: 0.447 ± 0.285
0.223GlnTyr: 0.223 ± 0.143
0.223GlnXaa: 0.223 ± 0.235
Arg
4.243ArgAla: 4.243 ± 1.692
0.447ArgCys: 0.447 ± 0.246
4.02ArgAsp: 4.02 ± 0.911
4.02ArgGlu: 4.02 ± 0.986
3.573ArgPhe: 3.573 ± 1.415
3.126ArgGly: 3.126 ± 0.779
1.34ArgHis: 1.34 ± 0.474
1.787ArgIle: 1.787 ± 0.405
1.787ArgLys: 1.787 ± 0.544
5.583ArgLeu: 5.583 ± 1.157
1.563ArgMet: 1.563 ± 0.57
3.126ArgAsn: 3.126 ± 1.314
1.563ArgPro: 1.563 ± 0.626
1.117ArgGln: 1.117 ± 0.596
3.126ArgArg: 3.126 ± 1.214
3.573ArgSer: 3.573 ± 1.109
2.68ArgThr: 2.68 ± 0.886
5.583ArgVal: 5.583 ± 1.527
1.787ArgTrp: 1.787 ± 0.709
2.01ArgTyr: 2.01 ± 0.686
0.0ArgXaa: 0.0 ± 0.0
Ser
6.029SerAla: 6.029 ± 1.346
1.563SerCys: 1.563 ± 0.465
6.253SerAsp: 6.253 ± 1.151
2.903SerGlu: 2.903 ± 0.674
3.35SerPhe: 3.35 ± 1.379
6.253SerGly: 6.253 ± 2.453
1.34SerHis: 1.34 ± 0.967
3.573SerIle: 3.573 ± 1.003
4.02SerLys: 4.02 ± 1.125
6.253SerLeu: 6.253 ± 1.354
1.787SerMet: 1.787 ± 0.612
4.02SerAsn: 4.02 ± 0.9
3.796SerPro: 3.796 ± 0.993
1.787SerGln: 1.787 ± 0.794
5.806SerArg: 5.806 ± 0.869
8.263SerSer: 8.263 ± 0.896
4.69SerThr: 4.69 ± 0.551
6.923SerVal: 6.923 ± 0.838
1.563SerTrp: 1.563 ± 0.971
1.117SerTyr: 1.117 ± 0.461
0.0SerXaa: 0.0 ± 0.0
Thr
3.126ThrAla: 3.126 ± 1.209
0.67ThrCys: 0.67 ± 0.34
3.573ThrAsp: 3.573 ± 1.499
1.34ThrGlu: 1.34 ± 0.589
2.233ThrPhe: 2.233 ± 0.809
3.796ThrGly: 3.796 ± 1.259
1.787ThrHis: 1.787 ± 1.368
1.787ThrIle: 1.787 ± 0.922
3.35ThrLys: 3.35 ± 0.904
6.699ThrLeu: 6.699 ± 0.909
1.34ThrMet: 1.34 ± 0.634
2.233ThrAsn: 2.233 ± 1.221
2.01ThrPro: 2.01 ± 0.6
1.34ThrGln: 1.34 ± 0.654
4.02ThrArg: 4.02 ± 1.296
2.68ThrSer: 2.68 ± 0.71
2.233ThrThr: 2.233 ± 1.832
4.02ThrVal: 4.02 ± 1.394
1.117ThrTrp: 1.117 ± 0.408
0.893ThrTyr: 0.893 ± 0.324
0.0ThrXaa: 0.0 ± 0.0
Val
6.923ValAla: 6.923 ± 1.532
2.01ValCys: 2.01 ± 1.239
6.699ValAsp: 6.699 ± 1.885
4.466ValGlu: 4.466 ± 1.205
3.126ValPhe: 3.126 ± 1.096
7.816ValGly: 7.816 ± 1.376
2.01ValHis: 2.01 ± 0.697
2.01ValIle: 2.01 ± 0.928
4.466ValLys: 4.466 ± 1.643
8.709ValLeu: 8.709 ± 1.304
1.117ValMet: 1.117 ± 0.562
4.02ValAsn: 4.02 ± 1.043
4.243ValPro: 4.243 ± 1.205
2.68ValGln: 2.68 ± 0.541
5.136ValArg: 5.136 ± 0.618
11.389ValSer: 11.389 ± 2.172
3.573ValThr: 3.573 ± 0.651
7.816ValVal: 7.816 ± 1.68
0.893ValTrp: 0.893 ± 0.741
3.126ValTyr: 3.126 ± 1.528
0.0ValXaa: 0.0 ± 0.0
Trp
0.893TrpAla: 0.893 ± 0.368
0.447TrpCys: 0.447 ± 0.548
0.223TrpAsp: 0.223 ± 0.143
0.67TrpGlu: 0.67 ± 0.428
0.447TrpPhe: 0.447 ± 0.507
0.67TrpGly: 0.67 ± 0.315
0.0TrpHis: 0.0 ± 0.0
0.447TrpIle: 0.447 ± 0.246
1.34TrpLys: 1.34 ± 0.542
1.563TrpLeu: 1.563 ± 0.757
0.0TrpMet: 0.0 ± 0.0
0.447TrpAsn: 0.447 ± 0.408
0.0TrpPro: 0.0 ± 0.0
1.34TrpGln: 1.34 ± 0.511
1.117TrpArg: 1.117 ± 0.504
1.563TrpSer: 1.563 ± 0.452
2.01TrpThr: 2.01 ± 1.367
1.563TrpVal: 1.563 ± 1.074
0.0TrpTrp: 0.0 ± 0.0
0.223TrpTyr: 0.223 ± 0.143
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.456TyrAla: 2.456 ± 0.889
0.893TyrCys: 0.893 ± 0.472
3.573TyrAsp: 3.573 ± 0.785
1.117TyrGlu: 1.117 ± 0.366
1.34TyrPhe: 1.34 ± 0.632
2.01TyrGly: 2.01 ± 1.195
1.563TyrHis: 1.563 ± 0.697
0.893TyrIle: 0.893 ± 0.488
1.117TyrLys: 1.117 ± 0.595
2.233TyrLeu: 2.233 ± 0.87
1.34TyrMet: 1.34 ± 0.575
1.563TyrAsn: 1.563 ± 0.665
1.117TyrPro: 1.117 ± 0.564
1.563TyrGln: 1.563 ± 0.998
1.787TyrArg: 1.787 ± 0.664
2.01TyrSer: 2.01 ± 0.465
1.563TyrThr: 1.563 ± 0.916
3.126TyrVal: 3.126 ± 0.846
0.223TyrTrp: 0.223 ± 0.143
0.67TyrTyr: 0.67 ± 0.358
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.223XaaGln: 0.223 ± 0.235
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (4479 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski