Amino acid dipepetide frequency for Salicibibacter kimchii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.604AlaAla: 6.604 ± 0.099	0.7AlaCys: 0.7 ± 0.03	4.356AlaAsp: 4.356 ± 0.078	5.64AlaGlu: 5.64 ± 0.08	3.619AlaPhe: 3.619 ± 0.066	6.042AlaGly: 6.042 ± 0.093	1.668AlaHis: 1.668 ± 0.043	5.72AlaIle: 5.72 ± 0.083	3.945AlaLys: 3.945 ± 0.066	8.195AlaLeu: 8.195 ± 0.098	2.44AlaMet: 2.44 ± 0.05	3.033AlaAsn: 3.033 ± 0.054	2.572AlaPro: 2.572 ± 0.058	2.429AlaGln: 2.429 ± 0.051	3.403AlaArg: 3.403 ± 0.066	4.557AlaSer: 4.557 ± 0.079	4.149AlaThr: 4.149 ± 0.066	5.865AlaVal: 5.865 ± 0.081	0.76AlaTrp: 0.76 ± 0.03	2.708AlaTyr: 2.708 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.449CysAla: 0.449 ± 0.021	0.085CysCys: 0.085 ± 0.01	0.349CysAsp: 0.349 ± 0.018	0.447CysGlu: 0.447 ± 0.022	0.309CysPhe: 0.309 ± 0.018	0.645CysGly: 0.645 ± 0.028	0.188CysHis: 0.188 ± 0.016	0.429CysIle: 0.429 ± 0.02	0.263CysLys: 0.263 ± 0.015	0.59CysLeu: 0.59 ± 0.026	0.168CysMet: 0.168 ± 0.012	0.246CysAsn: 0.246 ± 0.017	0.327CysPro: 0.327 ± 0.021	0.24CysGln: 0.24 ± 0.017	0.335CysArg: 0.335 ± 0.018	0.433CysSer: 0.433 ± 0.022	0.35CysThr: 0.35 ± 0.019	0.386CysVal: 0.386 ± 0.021	0.063CysTrp: 0.063 ± 0.008	0.208CysTyr: 0.208 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.388AspAla: 4.388 ± 0.064	0.301AspCys: 0.301 ± 0.018	3.703AspAsp: 3.703 ± 0.084	5.671AspGlu: 5.671 ± 0.112	2.373AspPhe: 2.373 ± 0.051	4.109AspGly: 4.109 ± 0.073	1.591AspHis: 1.591 ± 0.046	4.259AspIle: 4.259 ± 0.071	2.449AspLys: 2.449 ± 0.052	5.221AspLeu: 5.221 ± 0.066	1.76AspMet: 1.76 ± 0.038	1.866AspAsn: 1.866 ± 0.046	2.495AspPro: 2.495 ± 0.058	2.252AspGln: 2.252 ± 0.057	2.907AspArg: 2.907 ± 0.056	2.433AspSer: 2.433 ± 0.052	2.932AspThr: 2.932 ± 0.061	4.936AspVal: 4.936 ± 0.069	0.697AspTrp: 0.697 ± 0.028	2.148AspTyr: 2.148 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	6.986GluAla: 6.986 ± 0.095	0.338GluCys: 0.338 ± 0.021	5.134GluAsp: 5.134 ± 0.114	8.831GluGlu: 8.831 ± 0.142	2.054GluPhe: 2.054 ± 0.048	5.442GluGly: 5.442 ± 0.086	1.801GluHis: 1.801 ± 0.046	4.872GluIle: 4.872 ± 0.073	5.587GluLys: 5.587 ± 0.082	6.447GluLeu: 6.447 ± 0.098	2.697GluMet: 2.697 ± 0.068	3.937GluAsn: 3.937 ± 0.062	2.482GluPro: 2.482 ± 0.051	3.902GluGln: 3.902 ± 0.073	4.521GluArg: 4.521 ± 0.079	3.723GluSer: 3.723 ± 0.062	4.733GluThr: 4.733 ± 0.083	5.421GluVal: 5.421 ± 0.08	0.957GluTrp: 0.957 ± 0.028	1.977GluTyr: 1.977 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.222PheAla: 3.222 ± 0.065	0.282PheCys: 0.282 ± 0.017	2.395PheAsp: 2.395 ± 0.053	2.573PheGlu: 2.573 ± 0.052	2.164PhePhe: 2.164 ± 0.051	3.266PheGly: 3.266 ± 0.067	1.048PheHis: 1.048 ± 0.032	3.26PheIle: 3.26 ± 0.069	1.614PheLys: 1.614 ± 0.042	4.223PheLeu: 4.223 ± 0.075	1.219PheMet: 1.219 ± 0.035	1.499PheAsn: 1.499 ± 0.04	1.698PhePro: 1.698 ± 0.041	1.646PheGln: 1.646 ± 0.044	1.713PheArg: 1.713 ± 0.046	2.972PheSer: 2.972 ± 0.055	2.49PheThr: 2.49 ± 0.054	2.989PheVal: 2.989 ± 0.054	0.442PheTrp: 0.442 ± 0.024	1.49PheTyr: 1.49 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	5.687GlyAla: 5.687 ± 0.092	0.547GlyCys: 0.547 ± 0.025	4.0GlyAsp: 4.0 ± 0.066	5.568GlyGlu: 5.568 ± 0.094	3.306GlyPhe: 3.306 ± 0.061	5.349GlyGly: 5.349 ± 0.093	1.624GlyHis: 1.624 ± 0.048	5.353GlyIle: 5.353 ± 0.093	4.188GlyLys: 4.188 ± 0.072	6.638GlyLeu: 6.638 ± 0.096	2.46GlyMet: 2.46 ± 0.056	2.728GlyAsn: 2.728 ± 0.05	2.072GlyPro: 2.072 ± 0.05	2.342GlyGln: 2.342 ± 0.048	3.169GlyArg: 3.169 ± 0.066	4.294GlySer: 4.294 ± 0.069	4.25GlyThr: 4.25 ± 0.075	5.4GlyVal: 5.4 ± 0.085	0.852GlyTrp: 0.852 ± 0.032	2.702GlyTyr: 2.702 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.689HisAla: 1.689 ± 0.044	0.193HisCys: 0.193 ± 0.016	1.303HisAsp: 1.303 ± 0.039	1.773HisGlu: 1.773 ± 0.043	1.039HisPhe: 1.039 ± 0.035	1.667HisGly: 1.667 ± 0.038	0.771HisHis: 0.771 ± 0.033	1.459HisIle: 1.459 ± 0.036	0.879HisLys: 0.879 ± 0.028	2.337HisLeu: 2.337 ± 0.059	0.658HisMet: 0.658 ± 0.027	0.681HisAsn: 0.681 ± 0.031	1.301HisPro: 1.301 ± 0.036	0.886HisGln: 0.886 ± 0.033	1.233HisArg: 1.233 ± 0.037	1.251HisSer: 1.251 ± 0.031	1.205HisThr: 1.205 ± 0.034	1.765HisVal: 1.765 ± 0.048	0.329HisTrp: 0.329 ± 0.019	0.954HisTyr: 0.954 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.923IleAla: 5.923 ± 0.079	0.491IleCys: 0.491 ± 0.022	4.336IleAsp: 4.336 ± 0.059	5.102IleGlu: 5.102 ± 0.071	2.885IlePhe: 2.885 ± 0.068	5.645IleGly: 5.645 ± 0.088	1.617IleHis: 1.617 ± 0.042	4.761IleIle: 4.761 ± 0.1	2.94IleLys: 2.94 ± 0.057	5.948IleLeu: 5.948 ± 0.091	1.736IleMet: 1.736 ± 0.039	2.725IleAsn: 2.725 ± 0.054	3.035IlePro: 3.035 ± 0.058	2.463IleGln: 2.463 ± 0.052	3.188IleArg: 3.188 ± 0.061	4.154IleSer: 4.154 ± 0.079	3.851IleThr: 3.851 ± 0.063	5.169IleVal: 5.169 ± 0.074	0.577IleTrp: 0.577 ± 0.026	2.051IleTyr: 2.051 ± 0.046	0.0IleXaa: 0.0 ± 0.0
Lys	4.071LysAla: 4.071 ± 0.064	0.243LysCys: 0.243 ± 0.018	2.942LysAsp: 2.942 ± 0.057	5.365LysGlu: 5.365 ± 0.085	1.191LysPhe: 1.191 ± 0.034	3.605LysGly: 3.605 ± 0.071	1.25LysHis: 1.25 ± 0.044	3.212LysIle: 3.212 ± 0.062	4.287LysLys: 4.287 ± 0.083	3.952LysLeu: 3.952 ± 0.064	1.703LysMet: 1.703 ± 0.041	2.529LysAsn: 2.529 ± 0.056	1.838LysPro: 1.838 ± 0.045	2.518LysGln: 2.518 ± 0.053	3.223LysArg: 3.223 ± 0.06	2.487LysSer: 2.487 ± 0.054	3.198LysThr: 3.198 ± 0.06	3.226LysVal: 3.226 ± 0.069	0.628LysTrp: 0.628 ± 0.02	1.422LysTyr: 1.422 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	7.525LeuAla: 7.525 ± 0.105	0.598LeuCys: 0.598 ± 0.024	5.165LeuAsp: 5.165 ± 0.074	6.895LeuGlu: 6.895 ± 0.086	4.492LeuPhe: 4.492 ± 0.09	6.517LeuGly: 6.517 ± 0.088	2.148LeuHis: 2.148 ± 0.048	6.129LeuIle: 6.129 ± 0.085	4.779LeuLys: 4.779 ± 0.083	9.376LeuLeu: 9.376 ± 0.143	2.555LeuMet: 2.555 ± 0.054	3.733LeuAsn: 3.733 ± 0.071	4.212LeuPro: 4.212 ± 0.077	3.929LeuGln: 3.929 ± 0.067	4.15LeuArg: 4.15 ± 0.077	6.173LeuSer: 6.173 ± 0.079	5.233LeuThr: 5.233 ± 0.068	5.988LeuVal: 5.988 ± 0.09	0.807LeuTrp: 0.807 ± 0.031	2.884LeuTyr: 2.884 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.451MetAla: 2.451 ± 0.052	0.154MetCys: 0.154 ± 0.014	1.863MetAsp: 1.863 ± 0.045	2.473MetGlu: 2.473 ± 0.057	1.141MetPhe: 1.141 ± 0.035	1.971MetGly: 1.971 ± 0.051	0.579MetHis: 0.579 ± 0.025	2.253MetIle: 2.253 ± 0.05	1.99MetLys: 1.99 ± 0.046	2.778MetLeu: 2.778 ± 0.057	0.958MetMet: 0.958 ± 0.033	1.53MetAsn: 1.53 ± 0.041	1.175MetPro: 1.175 ± 0.033	1.167MetGln: 1.167 ± 0.034	1.295MetArg: 1.295 ± 0.035	1.798MetSer: 1.798 ± 0.044	1.915MetThr: 1.915 ± 0.047	1.915MetVal: 1.915 ± 0.049	0.189MetTrp: 0.189 ± 0.013	0.787MetTyr: 0.787 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.985AsnAla: 2.985 ± 0.053	0.257AsnCys: 0.257 ± 0.016	2.536AsnAsp: 2.536 ± 0.053	3.657AsnGlu: 3.657 ± 0.068	1.409AsnPhe: 1.409 ± 0.043	2.966AsnGly: 2.966 ± 0.06	1.075AsnHis: 1.075 ± 0.035	2.911AsnIle: 2.911 ± 0.062	1.927AsnLys: 1.927 ± 0.049	3.061AsnLeu: 3.061 ± 0.061	1.185AsnMet: 1.185 ± 0.038	1.595AsnAsn: 1.595 ± 0.052	1.844AsnPro: 1.844 ± 0.039	1.664AsnGln: 1.664 ± 0.045	2.109AsnArg: 2.109 ± 0.05	1.609AsnSer: 1.609 ± 0.042	1.926AsnThr: 1.926 ± 0.046	3.374AsnVal: 3.374 ± 0.058	0.457AsnTrp: 0.457 ± 0.023	1.326AsnTyr: 1.326 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	2.756ProAla: 2.756 ± 0.057	0.212ProCys: 0.212 ± 0.016	2.528ProAsp: 2.528 ± 0.057	3.536ProGlu: 3.536 ± 0.063	1.949ProPhe: 1.949 ± 0.043	2.767ProGly: 2.767 ± 0.055	0.857ProHis: 0.857 ± 0.031	2.552ProIle: 2.552 ± 0.047	1.823ProLys: 1.823 ± 0.048	3.719ProLeu: 3.719 ± 0.057	1.069ProMet: 1.069 ± 0.036	1.466ProAsn: 1.466 ± 0.038	1.349ProPro: 1.349 ± 0.041	1.158ProGln: 1.158 ± 0.027	1.47ProArg: 1.47 ± 0.043	2.504ProSer: 2.504 ± 0.052	1.994ProThr: 1.994 ± 0.042	3.045ProVal: 3.045 ± 0.057	0.411ProTrp: 0.411 ± 0.02	1.449ProTyr: 1.449 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.286GlnAla: 3.286 ± 0.066	0.21GlnCys: 0.21 ± 0.015	1.805GlnAsp: 1.805 ± 0.044	3.186GlnGlu: 3.186 ± 0.061	1.461GlnPhe: 1.461 ± 0.037	2.463GlnGly: 2.463 ± 0.049	0.846GlnHis: 0.846 ± 0.031	2.114GlnIle: 2.114 ± 0.044	2.233GlnLys: 2.233 ± 0.05	3.879GlnLeu: 3.879 ± 0.073	1.409GlnMet: 1.409 ± 0.04	1.484GlnAsn: 1.484 ± 0.045	1.406GlnPro: 1.406 ± 0.034	1.996GlnGln: 1.996 ± 0.065	1.951GlnArg: 1.951 ± 0.054	2.27GlnSer: 2.27 ± 0.053	2.29GlnThr: 2.29 ± 0.051	2.418GlnVal: 2.418 ± 0.044	0.478GlnTrp: 0.478 ± 0.022	1.142GlnTyr: 1.142 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	3.257ArgAla: 3.257 ± 0.074	0.335ArgCys: 0.335 ± 0.021	2.523ArgAsp: 2.523 ± 0.054	4.076ArgGlu: 4.076 ± 0.073	2.164ArgPhe: 2.164 ± 0.042	2.794ArgGly: 2.794 ± 0.059	1.079ArgHis: 1.079 ± 0.035	3.027ArgIle: 3.027 ± 0.056	3.183ArgLys: 3.183 ± 0.065	4.782ArgLeu: 4.782 ± 0.078	1.619ArgMet: 1.619 ± 0.044	1.875ArgAsn: 1.875 ± 0.048	1.631ArgPro: 1.631 ± 0.044	1.914ArgGln: 1.914 ± 0.047	2.54ArgArg: 2.54 ± 0.059	2.734ArgSer: 2.734 ± 0.052	2.479ArgThr: 2.479 ± 0.055	2.987ArgVal: 2.987 ± 0.065	0.574ArgTrp: 0.574 ± 0.025	1.737ArgTyr: 1.737 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	4.134SerAla: 4.134 ± 0.078	0.354SerCys: 0.354 ± 0.02	3.311SerAsp: 3.311 ± 0.062	4.229SerGlu: 4.229 ± 0.07	2.872SerPhe: 2.872 ± 0.052	4.662SerGly: 4.662 ± 0.066	1.254SerHis: 1.254 ± 0.035	4.132SerIle: 4.132 ± 0.07	2.753SerLys: 2.753 ± 0.055	5.75SerLeu: 5.75 ± 0.084	1.903SerMet: 1.903 ± 0.045	2.176SerAsn: 2.176 ± 0.048	2.159SerPro: 2.159 ± 0.048	1.864SerGln: 1.864 ± 0.048	2.569SerArg: 2.569 ± 0.051	3.435SerSer: 3.435 ± 0.062	2.943SerThr: 2.943 ± 0.053	4.021SerVal: 4.021 ± 0.068	0.556SerTrp: 0.556 ± 0.026	1.965SerTyr: 1.965 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.487ThrAla: 4.487 ± 0.072	0.352ThrCys: 0.352 ± 0.02	3.144ThrAsp: 3.144 ± 0.057	3.967ThrGlu: 3.967 ± 0.071	2.737ThrPhe: 2.737 ± 0.053	4.447ThrGly: 4.447 ± 0.071	1.193ThrHis: 1.193 ± 0.031	4.145ThrIle: 4.145 ± 0.067	2.566ThrLys: 2.566 ± 0.057	5.478ThrLeu: 5.478 ± 0.081	1.627ThrMet: 1.627 ± 0.035	2.138ThrAsn: 2.138 ± 0.051	2.405ThrPro: 2.405 ± 0.058	1.485ThrGln: 1.485 ± 0.039	2.23ThrArg: 2.23 ± 0.053	3.258ThrSer: 3.258 ± 0.059	3.166ThrThr: 3.166 ± 0.066	4.388ThrVal: 4.388 ± 0.064	0.601ThrTrp: 0.601 ± 0.023	1.927ThrTyr: 1.927 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	5.541ValAla: 5.541 ± 0.086	0.54ValCys: 0.54 ± 0.023	4.433ValAsp: 4.433 ± 0.075	5.274ValGlu: 5.274 ± 0.076	3.019ValPhe: 3.019 ± 0.057	4.9ValGly: 4.9 ± 0.084	1.683ValHis: 1.683 ± 0.043	5.271ValIle: 5.271 ± 0.082	3.418ValLys: 3.418 ± 0.058	6.696ValLeu: 6.696 ± 0.099	2.011ValMet: 2.011 ± 0.045	2.992ValAsn: 2.992 ± 0.053	2.915ValPro: 2.915 ± 0.053	2.664ValGln: 2.664 ± 0.052	3.126ValArg: 3.126 ± 0.066	4.613ValSer: 4.613 ± 0.071	4.321ValThr: 4.321 ± 0.068	5.197ValVal: 5.197 ± 0.093	0.642ValTrp: 0.642 ± 0.027	2.19ValTyr: 2.19 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.693TrpAla: 0.693 ± 0.03	0.073TrpCys: 0.073 ± 0.008	0.583TrpAsp: 0.583 ± 0.028	0.8TrpGlu: 0.8 ± 0.032	0.487TrpPhe: 0.487 ± 0.022	0.714TrpGly: 0.714 ± 0.031	0.25TrpHis: 0.25 ± 0.017	0.743TrpIle: 0.743 ± 0.03	0.61TrpLys: 0.61 ± 0.024	1.232TrpLeu: 1.232 ± 0.039	0.388TrpMet: 0.388 ± 0.022	0.426TrpAsn: 0.426 ± 0.019	0.3TrpPro: 0.3 ± 0.017	0.442TrpGln: 0.442 ± 0.022	0.47TrpArg: 0.47 ± 0.025	0.608TrpSer: 0.608 ± 0.027	0.575TrpThr: 0.575 ± 0.022	0.661TrpVal: 0.661 ± 0.025	0.126TrpTrp: 0.126 ± 0.011	0.302TrpTyr: 0.302 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.271TyrAla: 2.271 ± 0.049	0.244TyrCys: 0.244 ± 0.016	2.083TyrAsp: 2.083 ± 0.053	2.78TyrGlu: 2.78 ± 0.061	1.532TyrPhe: 1.532 ± 0.041	2.561TyrGly: 2.561 ± 0.059	0.849TyrHis: 0.849 ± 0.029	1.995TyrIle: 1.995 ± 0.049	1.455TyrLys: 1.455 ± 0.044	2.984TyrLeu: 2.984 ± 0.056	0.816TyrMet: 0.816 ± 0.023	1.216TyrAsn: 1.216 ± 0.034	1.4TyrPro: 1.4 ± 0.035	1.366TyrGln: 1.366 ± 0.044	1.71TyrArg: 1.71 ± 0.041	1.734TyrSer: 1.734 ± 0.04	1.74TyrThr: 1.74 ± 0.039	2.295TyrVal: 2.295 ± 0.044	0.338TyrTrp: 0.338 ± 0.017	1.281TyrTyr: 1.281 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3509 proteins (988862 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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