Penicillium italicum (Blue mold)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium

Average proteome isoelectric point is 6.41

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9993 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0A2LEZ8|A0A0A2LEZ8_PENIT Ribosomal protein L5 OS=Penicillium italicum OX=40296 GN=PITC_010380 PE=3 SV=1
MM1 pKa = 8.17PYY3 pKa = 9.38PYY5 pKa = 9.63HH6 pKa = 6.89HH7 pKa = 6.94SRR9 pKa = 11.84VLVGIFFGVSFWDD22 pKa = 4.12LFWDD26 pKa = 4.91LFWDD30 pKa = 4.75LFWDD34 pKa = 4.75LFWDD38 pKa = 4.75LFWDD42 pKa = 4.75LFWDD46 pKa = 4.75LFWDD50 pKa = 4.75LFWDD54 pKa = 4.75LFWDD58 pKa = 4.75LFWDD62 pKa = 4.75LFWDD66 pKa = 4.75LFWDD70 pKa = 4.75LFWDD74 pKa = 4.29LFWDD78 pKa = 4.03LFYY81 pKa = 11.59YY82 pKa = 10.07FLINQKK88 pKa = 9.6KK89 pKa = 9.36VKK91 pKa = 10.38ASLIPYY97 pKa = 9.3IDD99 pKa = 3.69YY100 pKa = 11.24

Molecular weight: 13.24 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0A2LH46|A0A0A2LH46_PENIT HAD-superfamily hydrolase subfamily IA variant 3 OS=Penicillium italicum OX=40296 GN=PITC_039880 PE=4 SV=1
MM1 pKa = 7.9RR2 pKa = 11.84LFCGRR7 pKa = 11.84PRR9 pKa = 11.84KK10 pKa = 9.15PRR12 pKa = 11.84PLRR15 pKa = 11.84QIIYY19 pKa = 10.56SSTCEE24 pKa = 3.45MWVYY28 pKa = 10.26VHH30 pKa = 6.74LVPFSFRR37 pKa = 11.84PHH39 pKa = 4.29MMKK42 pKa = 10.29RR43 pKa = 11.84HH44 pKa = 6.12KK45 pKa = 9.32KK46 pKa = 8.49TSICPSQLAGEE57 pKa = 4.45DD58 pKa = 4.09DD59 pKa = 4.65KK60 pKa = 11.78LSCLINSRR68 pKa = 11.84ISTLLQCSFSTRR80 pKa = 11.84RR81 pKa = 3.34

Molecular weight: 9.57 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9993

0

9993

4757581

29

7287

476.1

52.73

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.385 ± 0.022

1.171 ± 0.007

5.686 ± 0.017

6.256 ± 0.028

3.799 ± 0.016

6.691 ± 0.024

2.426 ± 0.011

5.051 ± 0.015

4.742 ± 0.019

8.979 ± 0.027

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.216 ± 0.009

3.751 ± 0.013

6.095 ± 0.027

4.064 ± 0.019

5.975 ± 0.024

8.443 ± 0.026

5.993 ± 0.021

6.111 ± 0.02

1.437 ± 0.009

2.726 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski