Amino acid dipepetide frequency for Pantoea wallisii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.036AlaAla: 12.036 ± 0.157	1.088AlaCys: 1.088 ± 0.031	5.33AlaAsp: 5.33 ± 0.07	6.111AlaGlu: 6.111 ± 0.086	3.768AlaPhe: 3.768 ± 0.06	8.453AlaGly: 8.453 ± 0.109	2.15AlaHis: 2.15 ± 0.049	6.041AlaIle: 6.041 ± 0.075	3.499AlaLys: 3.499 ± 0.066	13.695AlaLeu: 13.695 ± 0.131	3.162AlaMet: 3.162 ± 0.051	2.878AlaAsn: 2.878 ± 0.058	3.992AlaPro: 3.992 ± 0.055	5.447AlaGln: 5.447 ± 0.078	6.369AlaArg: 6.369 ± 0.081	6.061AlaSer: 6.061 ± 0.075	4.944AlaThr: 4.944 ± 0.075	7.129AlaVal: 7.129 ± 0.09	1.779AlaTrp: 1.779 ± 0.042	1.986AlaTyr: 1.986 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.931CysAla: 0.931 ± 0.031	0.17CysCys: 0.17 ± 0.013	0.544CysAsp: 0.544 ± 0.023	0.559CysGlu: 0.559 ± 0.022	0.394CysPhe: 0.394 ± 0.019	1.036CysGly: 1.036 ± 0.032	0.317CysHis: 0.317 ± 0.02	0.501CysIle: 0.501 ± 0.023	0.263CysLys: 0.263 ± 0.014	0.959CysLeu: 0.959 ± 0.025	0.209CysMet: 0.209 ± 0.013	0.288CysAsn: 0.288 ± 0.016	0.43CysPro: 0.43 ± 0.019	0.478CysGln: 0.478 ± 0.02	0.561CysArg: 0.561 ± 0.024	0.621CysSer: 0.621 ± 0.023	0.417CysThr: 0.417 ± 0.019	0.677CysVal: 0.677 ± 0.024	0.168CysTrp: 0.168 ± 0.012	0.288CysTyr: 0.288 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.74AspAla: 5.74 ± 0.077	0.453AspCys: 0.453 ± 0.02	3.026AspAsp: 3.026 ± 0.059	3.358AspGlu: 3.358 ± 0.055	2.157AspPhe: 2.157 ± 0.047	3.678AspGly: 3.678 ± 0.065	1.106AspHis: 1.106 ± 0.034	3.151AspIle: 3.151 ± 0.054	2.189AspLys: 2.189 ± 0.051	4.748AspLeu: 4.748 ± 0.069	1.282AspMet: 1.282 ± 0.034	2.051AspAsn: 2.051 ± 0.047	2.129AspPro: 2.129 ± 0.044	1.77AspGln: 1.77 ± 0.039	3.132AspArg: 3.132 ± 0.053	2.727AspSer: 2.727 ± 0.052	2.336AspThr: 2.336 ± 0.048	3.894AspVal: 3.894 ± 0.059	0.801AspTrp: 0.801 ± 0.025	1.848AspTyr: 1.848 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	5.756GluAla: 5.756 ± 0.082	0.379GluCys: 0.379 ± 0.019	2.139GluAsp: 2.139 ± 0.051	3.156GluGlu: 3.156 ± 0.072	1.657GluPhe: 1.657 ± 0.042	3.41GluGly: 3.41 ± 0.053	1.305GluHis: 1.305 ± 0.037	3.176GluIle: 3.176 ± 0.052	2.8GluLys: 2.8 ± 0.066	5.507GluLeu: 5.507 ± 0.079	1.682GluMet: 1.682 ± 0.038	2.08GluAsn: 2.08 ± 0.043	2.015GluPro: 2.015 ± 0.047	3.504GluGln: 3.504 ± 0.051	3.5GluArg: 3.5 ± 0.058	2.906GluSer: 2.906 ± 0.054	2.841GluThr: 2.841 ± 0.057	3.633GluVal: 3.633 ± 0.064	0.752GluTrp: 0.752 ± 0.024	1.273GluTyr: 1.273 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.879PheAla: 3.879 ± 0.056	0.523PheCys: 0.523 ± 0.022	2.28PheAsp: 2.28 ± 0.044	1.649PheGlu: 1.649 ± 0.041	1.58PhePhe: 1.58 ± 0.046	3.184PheGly: 3.184 ± 0.057	0.81PheHis: 0.81 ± 0.028	2.414PheIle: 2.414 ± 0.044	1.14PheLys: 1.14 ± 0.029	3.347PheLeu: 3.347 ± 0.061	0.997PheMet: 0.997 ± 0.029	1.643PheAsn: 1.643 ± 0.037	1.534PhePro: 1.534 ± 0.037	1.185PheGln: 1.185 ± 0.032	1.967PheArg: 1.967 ± 0.044	3.044PheSer: 3.044 ± 0.056	2.419PheThr: 2.419 ± 0.048	2.454PheVal: 2.454 ± 0.056	0.631PheTrp: 0.631 ± 0.025	1.109PheTyr: 1.109 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	6.741GlyAla: 6.741 ± 0.103	0.95GlyCys: 0.95 ± 0.029	3.775GlyAsp: 3.775 ± 0.065	4.482GlyGlu: 4.482 ± 0.064	3.36GlyPhe: 3.36 ± 0.057	5.41GlyGly: 5.41 ± 0.095	1.667GlyHis: 1.667 ± 0.038	4.796GlyIle: 4.796 ± 0.068	3.651GlyLys: 3.651 ± 0.059	7.584GlyLeu: 7.584 ± 0.094	2.383GlyMet: 2.383 ± 0.053	2.727GlyAsn: 2.727 ± 0.056	2.108GlyPro: 2.108 ± 0.041	2.972GlyGln: 2.972 ± 0.056	4.019GlyArg: 4.019 ± 0.067	4.448GlySer: 4.448 ± 0.083	3.759GlyThr: 3.759 ± 0.069	5.753GlyVal: 5.753 ± 0.081	1.365GlyTrp: 1.365 ± 0.036	2.575GlyTyr: 2.575 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.321HisAla: 2.321 ± 0.046	0.342HisCys: 0.342 ± 0.018	1.245HisAsp: 1.245 ± 0.033	1.106HisGlu: 1.106 ± 0.037	1.143HisPhe: 1.143 ± 0.029	1.776HisGly: 1.776 ± 0.049	0.803HisHis: 0.803 ± 0.028	1.243HisIle: 1.243 ± 0.034	0.737HisLys: 0.737 ± 0.026	2.366HisLeu: 2.366 ± 0.045	0.529HisMet: 0.529 ± 0.022	0.831HisAsn: 0.831 ± 0.028	1.434HisPro: 1.434 ± 0.04	1.364HisGln: 1.364 ± 0.037	1.31HisArg: 1.31 ± 0.035	1.369HisSer: 1.369 ± 0.033	1.137HisThr: 1.137 ± 0.031	1.288HisVal: 1.288 ± 0.034	0.476HisTrp: 0.476 ± 0.018	0.941HisTyr: 0.941 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.685IleAla: 6.685 ± 0.078	0.604IleCys: 0.604 ± 0.024	3.5IleAsp: 3.5 ± 0.06	3.088IleGlu: 3.088 ± 0.056	1.875IlePhe: 1.875 ± 0.044	4.692IleGly: 4.692 ± 0.07	1.096IleHis: 1.096 ± 0.03	2.989IleIle: 2.989 ± 0.052	2.035IleLys: 2.035 ± 0.046	4.616IleLeu: 4.616 ± 0.062	1.187IleMet: 1.187 ± 0.031	2.456IleAsn: 2.456 ± 0.055	2.397IlePro: 2.397 ± 0.046	1.766IleGln: 1.766 ± 0.033	2.929IleArg: 2.929 ± 0.046	3.615IleSer: 3.615 ± 0.054	3.468IleThr: 3.468 ± 0.059	3.886IleVal: 3.886 ± 0.063	0.687IleTrp: 0.687 ± 0.028	1.391IleTyr: 1.391 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	3.949LysAla: 3.949 ± 0.074	0.203LysCys: 0.203 ± 0.014	1.694LysAsp: 1.694 ± 0.042	2.03LysGlu: 2.03 ± 0.058	0.965LysPhe: 0.965 ± 0.03	2.739LysGly: 2.739 ± 0.056	0.788LysHis: 0.788 ± 0.027	2.043LysIle: 2.043 ± 0.047	1.815LysLys: 1.815 ± 0.047	3.858LysLeu: 3.858 ± 0.066	1.086LysMet: 1.086 ± 0.029	1.397LysAsn: 1.397 ± 0.038	2.03LysPro: 2.03 ± 0.045	1.911LysGln: 1.911 ± 0.044	2.42LysArg: 2.42 ± 0.043	2.144LysSer: 2.144 ± 0.043	2.19LysThr: 2.19 ± 0.048	2.684LysVal: 2.684 ± 0.058	0.418LysTrp: 0.418 ± 0.021	0.936LysTyr: 0.936 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	12.642LeuAla: 12.642 ± 0.124	1.235LeuCys: 1.235 ± 0.034	5.469LeuAsp: 5.469 ± 0.069	5.203LeuGlu: 5.203 ± 0.077	4.354LeuPhe: 4.354 ± 0.069	7.387LeuGly: 7.387 ± 0.096	2.524LeuHis: 2.524 ± 0.051	5.91LeuIle: 5.91 ± 0.074	4.138LeuLys: 4.138 ± 0.057	12.995LeuLeu: 12.995 ± 0.173	3.102LeuMet: 3.102 ± 0.043	4.181LeuAsn: 4.181 ± 0.065	5.931LeuPro: 5.931 ± 0.077	5.164LeuGln: 5.164 ± 0.087	6.658LeuArg: 6.658 ± 0.09	7.587LeuSer: 7.587 ± 0.08	6.432LeuThr: 6.432 ± 0.072	7.205LeuVal: 7.205 ± 0.093	1.476LeuTrp: 1.476 ± 0.037	2.528LeuTyr: 2.528 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.983MetAla: 2.983 ± 0.053	0.187MetCys: 0.187 ± 0.012	1.145MetAsp: 1.145 ± 0.028	1.122MetGlu: 1.122 ± 0.033	0.836MetPhe: 0.836 ± 0.026	1.789MetGly: 1.789 ± 0.042	0.577MetHis: 0.577 ± 0.022	1.441MetIle: 1.441 ± 0.032	1.354MetLys: 1.354 ± 0.039	3.231MetLeu: 3.231 ± 0.055	0.872MetMet: 0.872 ± 0.03	0.992MetAsn: 0.992 ± 0.029	1.35MetPro: 1.35 ± 0.034	1.321MetGln: 1.321 ± 0.034	1.577MetArg: 1.577 ± 0.039	1.858MetSer: 1.858 ± 0.036	1.741MetThr: 1.741 ± 0.038	1.863MetVal: 1.863 ± 0.043	0.27MetTrp: 0.27 ± 0.014	0.446MetTyr: 0.446 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.574AsnAla: 3.574 ± 0.059	0.305AsnCys: 0.305 ± 0.016	1.884AsnAsp: 1.884 ± 0.045	1.701AsnGlu: 1.701 ± 0.041	1.287AsnPhe: 1.287 ± 0.036	2.901AsnGly: 2.901 ± 0.058	0.808AsnHis: 0.808 ± 0.029	2.021AsnIle: 2.021 ± 0.049	1.325AsnLys: 1.325 ± 0.04	3.478AsnLeu: 3.478 ± 0.059	0.831AsnMet: 0.831 ± 0.026	1.363AsnAsn: 1.363 ± 0.037	2.03AsnPro: 2.03 ± 0.041	1.641AsnGln: 1.641 ± 0.038	2.018AsnArg: 2.018 ± 0.037	1.948AsnSer: 1.948 ± 0.054	1.742AsnThr: 1.742 ± 0.044	2.416AsnVal: 2.416 ± 0.044	0.573AsnTrp: 0.573 ± 0.028	1.006AsnTyr: 1.006 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	5.266ProAla: 5.266 ± 0.079	0.352ProCys: 0.352 ± 0.018	2.818ProAsp: 2.818 ± 0.049	3.074ProGlu: 3.074 ± 0.05	1.783ProPhe: 1.783 ± 0.044	3.664ProGly: 3.664 ± 0.053	1.176ProHis: 1.176 ± 0.033	1.774ProIle: 1.774 ± 0.043	1.315ProLys: 1.315 ± 0.039	5.363ProLeu: 5.363 ± 0.075	1.113ProMet: 1.113 ± 0.03	1.206ProAsn: 1.206 ± 0.032	1.738ProPro: 1.738 ± 0.039	2.643ProGln: 2.643 ± 0.051	2.083ProArg: 2.083 ± 0.05	1.951ProSer: 1.951 ± 0.039	1.908ProThr: 1.908 ± 0.046	3.872ProVal: 3.872 ± 0.065	0.747ProTrp: 0.747 ± 0.03	1.133ProTyr: 1.133 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.487GlnAla: 5.487 ± 0.087	0.364GlnCys: 0.364 ± 0.02	2.013GlnAsp: 2.013 ± 0.042	2.068GlnGlu: 2.068 ± 0.045	1.541GlnPhe: 1.541 ± 0.038	3.302GlnGly: 3.302 ± 0.06	1.598GlnHis: 1.598 ± 0.042	2.222GlnIle: 2.222 ± 0.038	1.618GlnLys: 1.618 ± 0.045	5.953GlnLeu: 5.953 ± 0.096	1.272GlnMet: 1.272 ± 0.034	1.388GlnAsn: 1.388 ± 0.037	2.813GlnPro: 2.813 ± 0.058	4.621GlnGln: 4.621 ± 0.094	3.868GlnArg: 3.868 ± 0.07	2.454GlnSer: 2.454 ± 0.048	2.213GlnThr: 2.213 ± 0.041	3.201GlnVal: 3.201 ± 0.052	0.716GlnTrp: 0.716 ± 0.028	1.138GlnTyr: 1.138 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	5.488ArgAla: 5.488 ± 0.067	0.56ArgCys: 0.56 ± 0.021	3.296ArgAsp: 3.296 ± 0.057	3.816ArgGlu: 3.816 ± 0.07	2.677ArgPhe: 2.677 ± 0.049	3.571ArgGly: 3.571 ± 0.061	1.745ArgHis: 1.745 ± 0.043	3.434ArgIle: 3.434 ± 0.055	2.152ArgLys: 2.152 ± 0.041	6.778ArgLeu: 6.778 ± 0.092	1.616ArgMet: 1.616 ± 0.037	2.037ArgAsn: 2.037 ± 0.047	2.29ArgPro: 2.29 ± 0.05	3.412ArgGln: 3.412 ± 0.064	3.697ArgArg: 3.697 ± 0.063	3.011ArgSer: 3.011 ± 0.051	2.575ArgThr: 2.575 ± 0.051	4.116ArgVal: 4.116 ± 0.064	1.107ArgTrp: 1.107 ± 0.031	2.203ArgTyr: 2.203 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.361SerAla: 6.361 ± 0.096	0.503SerCys: 0.503 ± 0.02	3.214SerAsp: 3.214 ± 0.06	3.192SerGlu: 3.192 ± 0.053	2.234SerPhe: 2.234 ± 0.042	5.532SerGly: 5.532 ± 0.077	1.446SerHis: 1.446 ± 0.034	2.727SerIle: 2.727 ± 0.054	1.878SerLys: 1.878 ± 0.045	6.748SerLeu: 6.748 ± 0.083	1.48SerMet: 1.48 ± 0.034	1.862SerAsn: 1.862 ± 0.041	2.527SerPro: 2.527 ± 0.046	2.61SerGln: 2.61 ± 0.055	3.423SerArg: 3.423 ± 0.052	3.454SerSer: 3.454 ± 0.065	2.834SerThr: 2.834 ± 0.054	4.263SerVal: 4.263 ± 0.061	1.104SerTrp: 1.104 ± 0.033	1.568SerTyr: 1.568 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	5.019ThrAla: 5.019 ± 0.073	0.394ThrCys: 0.394 ± 0.02	2.458ThrAsp: 2.458 ± 0.045	2.407ThrGlu: 2.407 ± 0.053	1.967ThrPhe: 1.967 ± 0.047	4.367ThrGly: 4.367 ± 0.07	1.276ThrHis: 1.276 ± 0.034	2.511ThrIle: 2.511 ± 0.053	1.325ThrLys: 1.325 ± 0.035	7.968ThrLeu: 7.968 ± 0.09	1.017ThrMet: 1.017 ± 0.029	1.398ThrAsn: 1.398 ± 0.043	3.167ThrPro: 3.167 ± 0.055	2.319ThrGln: 2.319 ± 0.047	3.192ThrArg: 3.192 ± 0.054	2.825ThrSer: 2.825 ± 0.056	2.722ThrThr: 2.722 ± 0.054	3.727ThrVal: 3.727 ± 0.065	0.749ThrTrp: 0.749 ± 0.027	1.099ThrTyr: 1.099 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.529ValAla: 7.529 ± 0.082	0.679ValCys: 0.679 ± 0.025	3.558ValAsp: 3.558 ± 0.061	3.688ValGlu: 3.688 ± 0.065	2.46ValPhe: 2.46 ± 0.052	4.627ValGly: 4.627 ± 0.072	1.322ValHis: 1.322 ± 0.032	4.563ValIle: 4.563 ± 0.063	2.847ValLys: 2.847 ± 0.053	7.561ValLeu: 7.561 ± 0.088	2.211ValMet: 2.211 ± 0.05	2.697ValAsn: 2.697 ± 0.051	3.027ValPro: 3.027 ± 0.057	2.637ValGln: 2.637 ± 0.052	3.86ValArg: 3.86 ± 0.052	4.533ValSer: 4.533 ± 0.058	4.354ValThr: 4.354 ± 0.064	5.309ValVal: 5.309 ± 0.084	0.923ValTrp: 0.923 ± 0.03	1.593ValTyr: 1.593 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.019TrpAla: 1.019 ± 0.032	0.181TrpCys: 0.181 ± 0.013	0.663TrpAsp: 0.663 ± 0.024	0.551TrpGlu: 0.551 ± 0.023	0.684TrpPhe: 0.684 ± 0.026	0.858TrpGly: 0.858 ± 0.031	0.532TrpHis: 0.532 ± 0.023	0.772TrpIle: 0.772 ± 0.027	0.428TrpLys: 0.428 ± 0.021	2.469TrpLeu: 2.469 ± 0.055	0.402TrpMet: 0.402 ± 0.017	0.466TrpAsn: 0.466 ± 0.022	0.724TrpPro: 0.724 ± 0.026	1.458TrpGln: 1.458 ± 0.04	1.146TrpArg: 1.146 ± 0.037	0.878TrpSer: 0.878 ± 0.028	0.578TrpThr: 0.578 ± 0.021	0.914TrpVal: 0.914 ± 0.033	0.253TrpTrp: 0.253 ± 0.016	0.431TrpTyr: 0.431 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.514TyrAla: 2.514 ± 0.042	0.339TyrCys: 0.339 ± 0.02	1.523TyrAsp: 1.523 ± 0.041	1.11TyrGlu: 1.11 ± 0.029	1.067TyrPhe: 1.067 ± 0.026	2.148TyrGly: 2.148 ± 0.05	0.714TyrHis: 0.714 ± 0.023	1.237TyrIle: 1.237 ± 0.035	0.789TyrLys: 0.789 ± 0.027	2.898TyrLeu: 2.898 ± 0.053	0.523TyrMet: 0.523 ± 0.024	0.91TyrAsn: 0.91 ± 0.034	1.312TyrPro: 1.312 ± 0.035	1.629TyrGln: 1.629 ± 0.035	1.853TyrArg: 1.853 ± 0.04	1.525TyrSer: 1.525 ± 0.044	1.297TyrThr: 1.297 ± 0.035	1.694TyrVal: 1.694 ± 0.04	0.412TyrTrp: 0.412 ± 0.022	0.808TyrTyr: 0.808 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3765 proteins (1157890 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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