Amino acid dipepetide frequency for Aegilops tauschii subsp. strangulata (Goatgrass)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.15AlaAla: 10.15 ± 0.022	1.493AlaCys: 1.493 ± 0.005	4.075AlaAsp: 4.075 ± 0.007	4.767AlaGlu: 4.767 ± 0.01	2.794AlaPhe: 2.794 ± 0.007	5.818AlaGly: 5.818 ± 0.011	1.736AlaHis: 1.736 ± 0.005	3.619AlaIle: 3.619 ± 0.007	3.838AlaLys: 3.838 ± 0.007	7.586AlaLeu: 7.586 ± 0.012	2.146AlaMet: 2.146 ± 0.006	2.621AlaAsn: 2.621 ± 0.006	4.392AlaPro: 4.392 ± 0.011	2.49AlaGln: 2.49 ± 0.006	4.803AlaArg: 4.803 ± 0.01	6.884AlaSer: 6.884 ± 0.012	4.291AlaThr: 4.291 ± 0.009	5.945AlaVal: 5.945 ± 0.011	0.912AlaTrp: 0.912 ± 0.004	1.961AlaTyr: 1.961 ± 0.005	0.0AlaXaa: 0.0 ± 0.0
Cys	1.307CysAla: 1.307 ± 0.005	0.598CysCys: 0.598 ± 0.004	0.891CysAsp: 0.891 ± 0.004	0.861CysGlu: 0.861 ± 0.003	0.88CysPhe: 0.88 ± 0.004	1.415CysGly: 1.415 ± 0.005	0.536CysHis: 0.536 ± 0.003	1.037CysIle: 1.037 ± 0.004	1.018CysLys: 1.018 ± 0.004	1.95CysLeu: 1.95 ± 0.006	0.483CysMet: 0.483 ± 0.002	0.734CysAsn: 0.734 ± 0.003	1.034CysPro: 1.034 ± 0.005	0.642CysGln: 0.642 ± 0.003	1.266CysArg: 1.266 ± 0.005	1.945CysSer: 1.945 ± 0.006	1.0CysThr: 1.0 ± 0.003	1.153CysVal: 1.153 ± 0.004	0.273CysTrp: 0.273 ± 0.002	0.563CysTyr: 0.563 ± 0.003	0.0CysXaa: 0.0 ± 0.0
Asp	4.45AspAla: 4.45 ± 0.009	0.947AspCys: 0.947 ± 0.004	3.821AspAsp: 3.821 ± 0.01	3.828AspGlu: 3.828 ± 0.009	2.096AspPhe: 2.096 ± 0.006	4.34AspGly: 4.34 ± 0.009	1.282AspHis: 1.282 ± 0.004	2.934AspIle: 2.934 ± 0.007	2.642AspLys: 2.642 ± 0.006	5.04AspLeu: 5.04 ± 0.01	1.447AspMet: 1.447 ± 0.005	1.92AspAsn: 1.92 ± 0.005	2.738AspPro: 2.738 ± 0.005	1.709AspGln: 1.709 ± 0.006	2.67AspArg: 2.67 ± 0.007	3.814AspSer: 3.814 ± 0.01	2.392AspThr: 2.392 ± 0.007	3.787AspVal: 3.787 ± 0.008	0.711AspTrp: 0.711 ± 0.003	1.468AspTyr: 1.468 ± 0.005	0.0AspXaa: 0.0 ± 0.0
Glu	5.086GluAla: 5.086 ± 0.01	0.91GluCys: 0.91 ± 0.004	3.733GluAsp: 3.733 ± 0.009	5.436GluGlu: 5.436 ± 0.014	2.081GluPhe: 2.081 ± 0.005	3.697GluGly: 3.697 ± 0.008	1.448GluHis: 1.448 ± 0.004	3.13GluIle: 3.13 ± 0.007	3.925GluLys: 3.925 ± 0.01	5.912GluLeu: 5.912 ± 0.011	1.648GluMet: 1.648 ± 0.005	2.426GluAsn: 2.426 ± 0.007	2.339GluPro: 2.339 ± 0.007	2.318GluGln: 2.318 ± 0.006	3.452GluArg: 3.452 ± 0.008	3.975GluSer: 3.975 ± 0.01	2.722GluThr: 2.722 ± 0.007	4.119GluVal: 4.119 ± 0.008	0.721GluTrp: 0.721 ± 0.003	1.581GluTyr: 1.581 ± 0.005	0.0GluXaa: 0.0 ± 0.0
Phe	2.705PheAla: 2.705 ± 0.006	0.862PheCys: 0.862 ± 0.004	2.168PheAsp: 2.168 ± 0.006	1.955PheGlu: 1.955 ± 0.006	1.759PhePhe: 1.759 ± 0.005	2.855PheGly: 2.855 ± 0.007	1.021PheHis: 1.021 ± 0.004	1.774PheIle: 1.774 ± 0.005	1.643PheLys: 1.643 ± 0.005	4.027PheLeu: 4.027 ± 0.008	0.883PheMet: 0.883 ± 0.004	1.367PheAsn: 1.367 ± 0.005	1.944PhePro: 1.944 ± 0.006	1.371PheGln: 1.371 ± 0.005	2.085PheArg: 2.085 ± 0.006	3.45PheSer: 3.45 ± 0.007	1.819PheThr: 1.819 ± 0.005	2.639PheVal: 2.639 ± 0.006	0.545PheTrp: 0.545 ± 0.003	1.131PheTyr: 1.131 ± 0.005	0.0PheXaa: 0.0 ± 0.0
Gly	5.488GlyAla: 5.488 ± 0.012	1.377GlyCys: 1.377 ± 0.005	3.783GlyAsp: 3.783 ± 0.009	3.768GlyGlu: 3.768 ± 0.007	2.791GlyPhe: 2.791 ± 0.006	6.23GlyGly: 6.23 ± 0.016	1.773GlyHis: 1.773 ± 0.005	3.237GlyIle: 3.237 ± 0.006	3.7GlyLys: 3.7 ± 0.008	6.007GlyLeu: 6.007 ± 0.011	1.682GlyMet: 1.682 ± 0.005	2.714GlyAsn: 2.714 ± 0.007	2.746GlyPro: 2.746 ± 0.007	2.322GlyGln: 2.322 ± 0.006	4.482GlyArg: 4.482 ± 0.009	5.979GlySer: 5.979 ± 0.009	3.539GlyThr: 3.539 ± 0.008	4.438GlyVal: 4.438 ± 0.009	0.938GlyTrp: 0.938 ± 0.004	2.04GlyTyr: 2.04 ± 0.006	0.0GlyXaa: 0.0 ± 0.0
His	1.901HisAla: 1.901 ± 0.004	0.557HisCys: 0.557 ± 0.003	1.314HisAsp: 1.314 ± 0.004	1.312HisGlu: 1.312 ± 0.005	0.994HisPhe: 0.994 ± 0.004	2.059HisGly: 2.059 ± 0.006	0.986HisHis: 0.986 ± 0.005	1.237HisIle: 1.237 ± 0.004	1.08HisLys: 1.08 ± 0.005	2.677HisLeu: 2.677 ± 0.007	0.601HisMet: 0.601 ± 0.003	0.879HisAsn: 0.879 ± 0.003	1.564HisPro: 1.564 ± 0.006	1.028HisGln: 1.028 ± 0.004	1.689HisArg: 1.689 ± 0.005	1.863HisSer: 1.863 ± 0.005	1.112HisThr: 1.112 ± 0.005	1.724HisVal: 1.724 ± 0.005	0.317HisTrp: 0.317 ± 0.002	0.677HisTyr: 0.677 ± 0.003	0.0HisXaa: 0.0 ± 0.0
Ile	3.551IleAla: 3.551 ± 0.007	1.082IleCys: 1.082 ± 0.004	2.618IleAsp: 2.618 ± 0.006	2.631IleGlu: 2.631 ± 0.007	1.982IlePhe: 1.982 ± 0.007	3.074IleGly: 3.074 ± 0.008	1.225IleHis: 1.225 ± 0.004	2.488IleIle: 2.488 ± 0.006	2.445IleLys: 2.445 ± 0.006	4.805IleLeu: 4.805 ± 0.01	1.073IleMet: 1.073 ± 0.004	1.789IleAsn: 1.789 ± 0.005	2.557IlePro: 2.557 ± 0.008	1.78IleGln: 1.78 ± 0.005	2.493IleArg: 2.493 ± 0.006	4.176IleSer: 4.176 ± 0.009	2.428IleThr: 2.428 ± 0.006	3.191IleVal: 3.191 ± 0.007	0.649IleTrp: 0.649 ± 0.003	1.384IleTyr: 1.384 ± 0.005	0.0IleXaa: 0.0 ± 0.0
Lys	3.898LysAla: 3.898 ± 0.009	0.885LysCys: 0.885 ± 0.004	2.96LysAsp: 2.96 ± 0.007	3.899LysGlu: 3.899 ± 0.009	1.773LysPhe: 1.773 ± 0.005	3.233LysGly: 3.233 ± 0.007	1.302LysHis: 1.302 ± 0.005	2.766LysIle: 2.766 ± 0.006	3.695LysLys: 3.695 ± 0.01	5.217LysLeu: 5.217 ± 0.011	1.319LysMet: 1.319 ± 0.005	2.057LysAsn: 2.057 ± 0.005	2.396LysPro: 2.396 ± 0.007	2.096LysGln: 2.096 ± 0.006	3.22LysArg: 3.22 ± 0.008	3.713LysSer: 3.713 ± 0.008	2.422LysThr: 2.422 ± 0.006	3.516LysVal: 3.516 ± 0.007	0.64LysTrp: 0.64 ± 0.003	1.488LysTyr: 1.488 ± 0.004	0.0LysXaa: 0.0 ± 0.0
Leu	7.711LeuAla: 7.711 ± 0.011	2.003LeuCys: 2.003 ± 0.005	5.218LeuAsp: 5.218 ± 0.008	5.989LeuGlu: 5.989 ± 0.012	3.625LeuPhe: 3.625 ± 0.008	5.945LeuGly: 5.945 ± 0.011	2.875LeuHis: 2.875 ± 0.007	3.985LeuIle: 3.985 ± 0.009	5.274LeuLys: 5.274 ± 0.01	10.672LeuLeu: 10.672 ± 0.017	2.078LeuMet: 2.078 ± 0.005	3.283LeuAsn: 3.283 ± 0.009	5.782LeuPro: 5.782 ± 0.01	4.377LeuGln: 4.377 ± 0.01	6.204LeuArg: 6.204 ± 0.01	8.105LeuSer: 8.105 ± 0.015	4.399LeuThr: 4.399 ± 0.009	6.582LeuVal: 6.582 ± 0.012	1.163LeuTrp: 1.163 ± 0.004	2.467LeuTyr: 2.467 ± 0.006	0.001LeuXaa: 0.001 ± 0.0
Met	2.222MetAla: 2.222 ± 0.006	0.381MetCys: 0.381 ± 0.002	1.489MetAsp: 1.489 ± 0.005	1.792MetGlu: 1.792 ± 0.005	0.848MetPhe: 0.848 ± 0.004	1.489MetGly: 1.489 ± 0.005	0.64MetHis: 0.64 ± 0.003	1.083MetIle: 1.083 ± 0.004	1.4MetLys: 1.4 ± 0.004	2.415MetLeu: 2.415 ± 0.006	0.672MetMet: 0.672 ± 0.003	0.889MetAsn: 0.889 ± 0.004	1.244MetPro: 1.244 ± 0.005	1.002MetGln: 1.002 ± 0.004	1.319MetArg: 1.319 ± 0.004	1.808MetSer: 1.808 ± 0.005	1.103MetThr: 1.103 ± 0.004	1.684MetVal: 1.684 ± 0.005	0.29MetTrp: 0.29 ± 0.002	0.631MetTyr: 0.631 ± 0.004	0.0MetXaa: 0.0 ± 0.0
Asn	2.596AsnAla: 2.596 ± 0.006	0.744AsnCys: 0.744 ± 0.003	1.815AsnAsp: 1.815 ± 0.005	1.977AsnGlu: 1.977 ± 0.005	1.509AsnPhe: 1.509 ± 0.004	2.799AsnGly: 2.799 ± 0.007	0.946AsnHis: 0.946 ± 0.004	2.18AsnIle: 2.18 ± 0.006	1.95AsnLys: 1.95 ± 0.006	3.852AsnLeu: 3.852 ± 0.011	1.01AsnMet: 1.01 ± 0.004	1.705AsnAsn: 1.705 ± 0.006	1.937AsnPro: 1.937 ± 0.005	1.411AsnGln: 1.411 ± 0.006	1.789AsnArg: 1.789 ± 0.005	3.005AsnSer: 3.005 ± 0.008	1.814AsnThr: 1.814 ± 0.005	2.396AsnVal: 2.396 ± 0.007	0.477AsnTrp: 0.477 ± 0.003	1.068AsnTyr: 1.068 ± 0.004	0.0AsnXaa: 0.0 ± 0.0
Pro	4.775ProAla: 4.775 ± 0.01	0.926ProCys: 0.926 ± 0.004	2.755ProAsp: 2.755 ± 0.007	3.281ProGlu: 3.281 ± 0.007	1.905ProPhe: 1.905 ± 0.006	3.367ProGly: 3.367 ± 0.007	1.303ProHis: 1.303 ± 0.005	1.982ProIle: 1.982 ± 0.005	2.396ProLys: 2.396 ± 0.006	4.597ProLeu: 4.597 ± 0.009	1.088ProMet: 1.088 ± 0.005	1.924ProAsn: 1.924 ± 0.005	4.811ProPro: 4.811 ± 0.017	1.867ProGln: 1.867 ± 0.006	3.364ProArg: 3.364 ± 0.009	5.368ProSer: 5.368 ± 0.011	2.788ProThr: 2.788 ± 0.006	3.44ProVal: 3.44 ± 0.006	0.674ProTrp: 0.674 ± 0.003	1.294ProTyr: 1.294 ± 0.004	0.0ProXaa: 0.0 ± 0.0
Gln	2.732GlnAla: 2.732 ± 0.007	0.628GlnCys: 0.628 ± 0.003	1.775GlnAsp: 1.775 ± 0.005	2.413GlnGlu: 2.413 ± 0.008	1.308GlnPhe: 1.308 ± 0.005	2.332GlnGly: 2.332 ± 0.006	1.06GlnHis: 1.06 ± 0.005	1.794GlnIle: 1.794 ± 0.005	2.062GlnLys: 2.062 ± 0.006	3.724GlnLeu: 3.724 ± 0.007	0.947GlnMet: 0.947 ± 0.004	1.458GlnAsn: 1.458 ± 0.005	1.929GlnPro: 1.929 ± 0.007	2.187GlnGln: 2.187 ± 0.012	2.33GlnArg: 2.33 ± 0.007	2.692GlnSer: 2.692 ± 0.007	1.616GlnThr: 1.616 ± 0.005	2.427GlnVal: 2.427 ± 0.005	0.459GlnTrp: 0.459 ± 0.003	0.973GlnTyr: 0.973 ± 0.004	0.0GlnXaa: 0.0 ± 0.0
Arg	4.63ArgAla: 4.63 ± 0.009	1.24ArgCys: 1.24 ± 0.005	2.958ArgAsp: 2.958 ± 0.008	3.392ArgGlu: 3.392 ± 0.009	2.203ArgPhe: 2.203 ± 0.005	3.969ArgGly: 3.969 ± 0.009	1.613ArgHis: 1.613 ± 0.005	2.686ArgIle: 2.686 ± 0.006	3.416ArgLys: 3.416 ± 0.009	5.832ArgLeu: 5.832 ± 0.011	1.418ArgMet: 1.418 ± 0.005	2.19ArgAsn: 2.19 ± 0.005	3.301ArgPro: 3.301 ± 0.01	2.135ArgGln: 2.135 ± 0.007	5.641ArgArg: 5.641 ± 0.015	4.907ArgSer: 4.907 ± 0.01	2.777ArgThr: 2.777 ± 0.007	3.622ArgVal: 3.622 ± 0.008	0.913ArgTrp: 0.913 ± 0.004	1.618ArgTyr: 1.618 ± 0.005	0.0ArgXaa: 0.0 ± 0.0
Ser	6.369SerAla: 6.369 ± 0.01	1.775SerCys: 1.775 ± 0.006	4.178SerAsp: 4.178 ± 0.009	4.324SerGlu: 4.324 ± 0.01	3.42SerPhe: 3.42 ± 0.007	5.884SerGly: 5.884 ± 0.011	1.899SerHis: 1.899 ± 0.006	3.86SerIle: 3.86 ± 0.008	4.099SerLys: 4.099 ± 0.01	8.064SerLeu: 8.064 ± 0.013	2.028SerMet: 2.028 ± 0.006	3.155SerAsn: 3.155 ± 0.008	4.81SerPro: 4.81 ± 0.012	2.738SerGln: 2.738 ± 0.007	4.81SerArg: 4.81 ± 0.011	9.819SerSer: 9.819 ± 0.019	4.653SerThr: 4.653 ± 0.01	5.145SerVal: 5.145 ± 0.009	1.157SerTrp: 1.157 ± 0.005	2.184SerTyr: 2.184 ± 0.006	0.0SerXaa: 0.0 ± 0.0
Thr	4.054ThrAla: 4.054 ± 0.008	0.987ThrCys: 0.987 ± 0.004	2.414ThrAsp: 2.414 ± 0.006	2.79ThrGlu: 2.79 ± 0.008	1.831ThrPhe: 1.831 ± 0.005	3.523ThrGly: 3.523 ± 0.008	1.077ThrHis: 1.077 ± 0.004	2.473ThrIle: 2.473 ± 0.005	2.418ThrLys: 2.418 ± 0.006	4.514ThrLeu: 4.514 ± 0.009	1.245ThrMet: 1.245 ± 0.004	1.836ThrAsn: 1.836 ± 0.005	2.835ThrPro: 2.835 ± 0.008	1.478ThrGln: 1.478 ± 0.005	2.636ThrArg: 2.636 ± 0.006	4.502ThrSer: 4.502 ± 0.009	2.909ThrThr: 2.909 ± 0.008	3.546ThrVal: 3.546 ± 0.007	0.635ThrTrp: 0.635 ± 0.004	1.373ThrTyr: 1.373 ± 0.004	0.0ThrXaa: 0.0 ± 0.0
Val	5.841ValAla: 5.841 ± 0.01	1.295ValCys: 1.295 ± 0.004	3.906ValAsp: 3.906 ± 0.007	4.101ValGlu: 4.101 ± 0.008	2.51ValPhe: 2.51 ± 0.006	4.262ValGly: 4.262 ± 0.009	1.764ValHis: 1.764 ± 0.005	3.115ValIle: 3.115 ± 0.007	3.378ValLys: 3.378 ± 0.008	6.786ValLeu: 6.786 ± 0.011	1.541ValMet: 1.541 ± 0.005	2.297ValAsn: 2.297 ± 0.006	3.719ValPro: 3.719 ± 0.008	2.468ValGln: 2.468 ± 0.006	3.725ValArg: 3.725 ± 0.007	5.212ValSer: 5.212 ± 0.009	3.301ValThr: 3.301 ± 0.008	5.126ValVal: 5.126 ± 0.011	0.807ValTrp: 0.807 ± 0.003	1.875ValTyr: 1.875 ± 0.006	0.0ValXaa: 0.0 ± 0.0
Trp	0.914TrpAla: 0.914 ± 0.004	0.268TrpCys: 0.268 ± 0.002	0.697TrpAsp: 0.697 ± 0.004	0.732TrpGlu: 0.732 ± 0.003	0.508TrpPhe: 0.508 ± 0.003	0.718TrpGly: 0.718 ± 0.004	0.338TrpHis: 0.338 ± 0.002	0.641TrpIle: 0.641 ± 0.003	0.786TrpLys: 0.786 ± 0.003	1.251TrpLeu: 1.251 ± 0.004	0.354TrpMet: 0.354 ± 0.002	0.581TrpAsn: 0.581 ± 0.003	0.593TrpPro: 0.593 ± 0.003	0.479TrpGln: 0.479 ± 0.003	0.976TrpArg: 0.976 ± 0.004	1.028TrpSer: 1.028 ± 0.004	0.669TrpThr: 0.669 ± 0.003	0.787TrpVal: 0.787 ± 0.004	0.247TrpTrp: 0.247 ± 0.002	0.35TrpTyr: 0.35 ± 0.003	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.94TyrAla: 1.94 ± 0.005	0.628TyrCys: 0.628 ± 0.003	1.471TyrAsp: 1.471 ± 0.005	1.41TyrGlu: 1.41 ± 0.005	1.187TyrPhe: 1.187 ± 0.004	2.027TyrGly: 2.027 ± 0.006	0.744TyrHis: 0.744 ± 0.004	1.403TyrIle: 1.403 ± 0.004	1.328TyrLys: 1.328 ± 0.004	2.81TyrLeu: 2.81 ± 0.007	0.734TyrMet: 0.734 ± 0.003	1.153TyrAsn: 1.153 ± 0.005	1.234TyrPro: 1.234 ± 0.005	0.947TyrGln: 0.947 ± 0.004	1.508TyrArg: 1.508 ± 0.004	2.126TyrSer: 2.126 ± 0.006	1.321TyrThr: 1.321 ± 0.004	1.763TyrVal: 1.763 ± 0.005	0.392TyrTrp: 0.392 ± 0.003	0.926TyrTyr: 0.926 ± 0.005	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.075XaaXaa: 0.075 ± 0.01

Statistics based on 214162 proteins (72665765 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---