Amino acid dipepetide frequency for Beauveria bassiana D1-5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.26AlaAla: 12.26 ± 0.084	1.149AlaCys: 1.149 ± 0.016	5.109AlaAsp: 5.109 ± 0.029	5.612AlaGlu: 5.612 ± 0.045	3.3AlaPhe: 3.3 ± 0.026	6.843AlaGly: 6.843 ± 0.043	2.034AlaHis: 2.034 ± 0.019	4.556AlaIle: 4.556 ± 0.037	4.3AlaLys: 4.3 ± 0.033	9.067AlaLeu: 9.067 ± 0.051	2.289AlaMet: 2.289 ± 0.023	3.162AlaAsn: 3.162 ± 0.025	5.048AlaPro: 5.048 ± 0.043	3.901AlaGln: 3.901 ± 0.035	5.673AlaArg: 5.673 ± 0.036	7.622AlaSer: 7.622 ± 0.041	5.814AlaThr: 5.814 ± 0.035	6.373AlaVal: 6.373 ± 0.04	1.326AlaTrp: 1.326 ± 0.016	2.169AlaTyr: 2.169 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.058CysAla: 1.058 ± 0.015	0.231CysCys: 0.231 ± 0.008	0.664CysAsp: 0.664 ± 0.012	0.597CysGlu: 0.597 ± 0.01	0.514CysPhe: 0.514 ± 0.009	0.972CysGly: 0.972 ± 0.016	0.324CysHis: 0.324 ± 0.008	0.651CysIle: 0.651 ± 0.012	0.493CysLys: 0.493 ± 0.01	1.205CysLeu: 1.205 ± 0.015	0.259CysMet: 0.259 ± 0.006	0.414CysAsn: 0.414 ± 0.01	0.64CysPro: 0.64 ± 0.012	0.453CysGln: 0.453 ± 0.01	0.788CysArg: 0.788 ± 0.012	0.86CysSer: 0.86 ± 0.013	0.657CysThr: 0.657 ± 0.012	0.779CysVal: 0.779 ± 0.014	0.19CysTrp: 0.19 ± 0.006	0.33CysTyr: 0.33 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.699AspAla: 5.699 ± 0.035	0.669AspCys: 0.669 ± 0.012	4.619AspAsp: 4.619 ± 0.051	4.499AspGlu: 4.499 ± 0.042	2.179AspPhe: 2.179 ± 0.02	4.48AspGly: 4.48 ± 0.031	1.179AspHis: 1.179 ± 0.016	2.925AspIle: 2.925 ± 0.024	2.639AspLys: 2.639 ± 0.027	4.79AspLeu: 4.79 ± 0.031	1.394AspMet: 1.394 ± 0.015	1.972AspAsn: 1.972 ± 0.019	2.873AspPro: 2.873 ± 0.022	1.779AspGln: 1.779 ± 0.018	3.039AspArg: 3.039 ± 0.03	3.921AspSer: 3.921 ± 0.028	2.884AspThr: 2.884 ± 0.022	3.818AspVal: 3.818 ± 0.028	0.872AspTrp: 0.872 ± 0.011	1.618AspTyr: 1.618 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.764GluAla: 5.764 ± 0.039	0.581GluCys: 0.581 ± 0.011	3.7GluAsp: 3.7 ± 0.036	4.756GluGlu: 4.756 ± 0.066	1.856GluPhe: 1.856 ± 0.018	3.356GluGly: 3.356 ± 0.027	1.416GluHis: 1.416 ± 0.016	2.755GluIle: 2.755 ± 0.024	3.277GluLys: 3.277 ± 0.036	5.274GluLeu: 5.274 ± 0.034	1.481GluMet: 1.481 ± 0.017	2.105GluAsn: 2.105 ± 0.021	2.717GluPro: 2.717 ± 0.038	2.751GluGln: 2.751 ± 0.03	3.763GluArg: 3.763 ± 0.029	3.867GluSer: 3.867 ± 0.029	3.342GluThr: 3.342 ± 0.024	3.307GluVal: 3.307 ± 0.027	0.807GluTrp: 0.807 ± 0.012	1.542GluTyr: 1.542 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.383PheAla: 3.383 ± 0.026	0.549PheCys: 0.549 ± 0.01	2.339PheAsp: 2.339 ± 0.02	1.957PheGlu: 1.957 ± 0.016	1.57PhePhe: 1.57 ± 0.018	2.894PheGly: 2.894 ± 0.026	0.85PheHis: 0.85 ± 0.012	1.784PheIle: 1.784 ± 0.019	1.391PheLys: 1.391 ± 0.016	3.279PheLeu: 3.279 ± 0.03	0.8PheMet: 0.8 ± 0.01	1.396PheAsn: 1.396 ± 0.017	1.744PhePro: 1.744 ± 0.018	1.316PheGln: 1.316 ± 0.016	1.924PheArg: 1.924 ± 0.019	2.897PheSer: 2.897 ± 0.026	2.109PheThr: 2.109 ± 0.022	2.384PheVal: 2.384 ± 0.023	0.622PheTrp: 0.622 ± 0.011	1.08PheTyr: 1.08 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	6.138GlyAla: 6.138 ± 0.039	0.883GlyCys: 0.883 ± 0.014	3.865GlyAsp: 3.865 ± 0.03	3.725GlyGlu: 3.725 ± 0.026	2.806GlyPhe: 2.806 ± 0.025	6.27GlyGly: 6.27 ± 0.06	1.759GlyHis: 1.759 ± 0.02	3.652GlyIle: 3.652 ± 0.027	3.527GlyLys: 3.527 ± 0.026	6.27GlyLeu: 6.27 ± 0.039	1.677GlyMet: 1.677 ± 0.018	2.643GlyAsn: 2.643 ± 0.032	3.091GlyPro: 3.091 ± 0.027	2.795GlyGln: 2.795 ± 0.026	4.332GlyArg: 4.332 ± 0.033	5.564GlySer: 5.564 ± 0.054	3.873GlyThr: 3.873 ± 0.034	4.582GlyVal: 4.582 ± 0.04	1.173GlyTrp: 1.173 ± 0.014	2.139GlyTyr: 2.139 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.105HisAla: 2.105 ± 0.021	0.344HisCys: 0.344 ± 0.008	1.405HisAsp: 1.405 ± 0.017	1.266HisGlu: 1.266 ± 0.016	0.923HisPhe: 0.923 ± 0.014	1.889HisGly: 1.889 ± 0.021	0.938HisHis: 0.938 ± 0.014	1.186HisIle: 1.186 ± 0.015	0.888HisLys: 0.888 ± 0.013	2.265HisLeu: 2.265 ± 0.021	0.526HisMet: 0.526 ± 0.01	0.845HisAsn: 0.845 ± 0.012	1.488HisPro: 1.488 ± 0.017	1.084HisGln: 1.084 ± 0.019	1.619HisArg: 1.619 ± 0.018	1.698HisSer: 1.698 ± 0.018	1.207HisThr: 1.207 ± 0.016	1.506HisVal: 1.506 ± 0.016	0.353HisTrp: 0.353 ± 0.008	0.701HisTyr: 0.701 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.604IleAla: 4.604 ± 0.035	0.69IleCys: 0.69 ± 0.011	2.892IleAsp: 2.892 ± 0.025	2.735IleGlu: 2.735 ± 0.026	1.848IlePhe: 1.848 ± 0.023	3.334IleGly: 3.334 ± 0.025	1.133IleHis: 1.133 ± 0.012	2.426IleIle: 2.426 ± 0.027	2.112IleLys: 2.112 ± 0.018	4.336IleLeu: 4.336 ± 0.034	1.038IleMet: 1.038 ± 0.015	1.795IleAsn: 1.795 ± 0.017	2.657IlePro: 2.657 ± 0.023	1.772IleGln: 1.772 ± 0.017	2.696IleArg: 2.696 ± 0.024	3.508IleSer: 3.508 ± 0.031	2.757IleThr: 2.757 ± 0.028	3.223IleVal: 3.223 ± 0.028	0.656IleTrp: 0.656 ± 0.01	1.291IleTyr: 1.291 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.291LysAla: 4.291 ± 0.035	0.442LysCys: 0.442 ± 0.01	2.593LysAsp: 2.593 ± 0.024	2.917LysGlu: 2.917 ± 0.031	1.363LysPhe: 1.363 ± 0.016	2.769LysGly: 2.769 ± 0.024	1.078LysHis: 1.078 ± 0.014	2.103LysIle: 2.103 ± 0.024	3.076LysLys: 3.076 ± 0.058	4.16LysLeu: 4.16 ± 0.029	1.06LysMet: 1.06 ± 0.014	1.648LysAsn: 1.648 ± 0.017	2.569LysPro: 2.569 ± 0.027	1.971LysGln: 1.971 ± 0.021	3.178LysArg: 3.178 ± 0.027	3.192LysSer: 3.192 ± 0.029	2.84LysThr: 2.84 ± 0.023	2.705LysVal: 2.705 ± 0.025	0.604LysTrp: 0.604 ± 0.011	1.24LysTyr: 1.24 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	9.191LeuAla: 9.191 ± 0.049	1.238LeuCys: 1.238 ± 0.016	5.326LeuAsp: 5.326 ± 0.034	5.233LeuGlu: 5.233 ± 0.041	3.446LeuPhe: 3.446 ± 0.026	6.186LeuGly: 6.186 ± 0.043	2.284LeuHis: 2.284 ± 0.023	3.994LeuIle: 3.994 ± 0.031	3.956LeuLys: 3.956 ± 0.034	8.933LeuLeu: 8.933 ± 0.062	1.93LeuMet: 1.93 ± 0.019	3.108LeuAsn: 3.108 ± 0.028	5.549LeuPro: 5.549 ± 0.033	4.0LeuGln: 4.0 ± 0.029	6.046LeuArg: 6.046 ± 0.037	7.049LeuSer: 7.049 ± 0.039	4.951LeuThr: 4.951 ± 0.037	5.857LeuVal: 5.857 ± 0.036	1.225LeuTrp: 1.225 ± 0.014	2.297LeuTyr: 2.297 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.497MetAla: 2.497 ± 0.021	0.246MetCys: 0.246 ± 0.007	1.246MetAsp: 1.246 ± 0.017	1.207MetGlu: 1.207 ± 0.015	0.72MetPhe: 0.72 ± 0.012	1.514MetGly: 1.514 ± 0.019	0.534MetHis: 0.534 ± 0.011	0.988MetIle: 0.988 ± 0.013	0.987MetLys: 0.987 ± 0.012	2.158MetLeu: 2.158 ± 0.02	0.658MetMet: 0.658 ± 0.011	0.773MetAsn: 0.773 ± 0.013	1.384MetPro: 1.384 ± 0.017	0.984MetGln: 0.984 ± 0.016	1.388MetArg: 1.388 ± 0.017	1.813MetSer: 1.813 ± 0.019	1.423MetThr: 1.423 ± 0.015	1.384MetVal: 1.384 ± 0.014	0.254MetTrp: 0.254 ± 0.007	0.538MetTyr: 0.538 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.281AsnAla: 3.281 ± 0.024	0.413AsnCys: 0.413 ± 0.009	1.988AsnAsp: 1.988 ± 0.021	1.861AsnGlu: 1.861 ± 0.02	1.28AsnPhe: 1.28 ± 0.017	2.976AsnGly: 2.976 ± 0.032	0.85AsnHis: 0.85 ± 0.014	1.926AsnIle: 1.926 ± 0.017	1.551AsnLys: 1.551 ± 0.019	3.142AsnLeu: 3.142 ± 0.024	0.87AsnMet: 0.87 ± 0.012	1.499AsnAsn: 1.499 ± 0.023	2.128AsnPro: 2.128 ± 0.022	1.301AsnGln: 1.301 ± 0.018	1.902AsnArg: 1.902 ± 0.016	2.498AsnSer: 2.498 ± 0.022	2.016AsnThr: 2.016 ± 0.021	2.32AsnVal: 2.32 ± 0.024	0.538AsnTrp: 0.538 ± 0.01	1.018AsnTyr: 1.018 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.683ProAla: 5.683 ± 0.044	0.533ProCys: 0.533 ± 0.011	3.198ProAsp: 3.198 ± 0.023	3.554ProGlu: 3.554 ± 0.031	1.932ProPhe: 1.932 ± 0.019	3.908ProGly: 3.908 ± 0.035	1.276ProHis: 1.276 ± 0.014	2.244ProIle: 2.244 ± 0.023	2.354ProLys: 2.354 ± 0.024	4.762ProLeu: 4.762 ± 0.034	1.091ProMet: 1.091 ± 0.015	1.891ProAsn: 1.891 ± 0.02	4.575ProPro: 4.575 ± 0.069	2.405ProGln: 2.405 ± 0.027	3.328ProArg: 3.328 ± 0.031	4.961ProSer: 4.961 ± 0.042	3.459ProThr: 3.459 ± 0.038	3.632ProVal: 3.632 ± 0.029	0.714ProTrp: 0.714 ± 0.011	1.327ProTyr: 1.327 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.879GlnAla: 3.879 ± 0.035	0.43GlnCys: 0.43 ± 0.009	2.164GlnAsp: 2.164 ± 0.023	2.25GlnGlu: 2.25 ± 0.021	1.305GlnPhe: 1.305 ± 0.015	2.573GlnGly: 2.573 ± 0.024	1.247GlnHis: 1.247 ± 0.018	1.882GlnIle: 1.882 ± 0.017	1.905GlnLys: 1.905 ± 0.019	3.902GlnLeu: 3.902 ± 0.032	0.96GlnMet: 0.96 ± 0.013	1.462GlnAsn: 1.462 ± 0.016	2.567GlnPro: 2.567 ± 0.031	3.04GlnGln: 3.04 ± 0.06	2.98GlnArg: 2.98 ± 0.024	2.975GlnSer: 2.975 ± 0.029	2.3GlnThr: 2.3 ± 0.021	2.413GlnVal: 2.413 ± 0.022	0.568GlnTrp: 0.568 ± 0.01	1.116GlnTyr: 1.116 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.314ArgAla: 5.314 ± 0.033	0.76ArgCys: 0.76 ± 0.013	3.605ArgAsp: 3.605 ± 0.036	3.654ArgGlu: 3.654 ± 0.028	2.238ArgPhe: 2.238 ± 0.021	3.984ArgGly: 3.984 ± 0.03	1.759ArgHis: 1.759 ± 0.02	2.917ArgIle: 2.917 ± 0.022	3.054ArgLys: 3.054 ± 0.028	5.887ArgLeu: 5.887 ± 0.04	1.342ArgMet: 1.342 ± 0.015	2.203ArgAsn: 2.203 ± 0.022	3.444ArgPro: 3.444 ± 0.031	2.945ArgGln: 2.945 ± 0.024	5.378ArgArg: 5.378 ± 0.046	4.435ArgSer: 4.435 ± 0.037	3.112ArgThr: 3.112 ± 0.021	3.542ArgVal: 3.542 ± 0.027	0.935ArgTrp: 0.935 ± 0.014	1.697ArgTyr: 1.697 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	7.026SerAla: 7.026 ± 0.043	0.81SerCys: 0.81 ± 0.013	4.012SerAsp: 4.012 ± 0.028	3.706SerGlu: 3.706 ± 0.027	2.79SerPhe: 2.79 ± 0.024	5.515SerGly: 5.515 ± 0.052	1.843SerHis: 1.843 ± 0.023	3.597SerIle: 3.597 ± 0.027	3.341SerLys: 3.341 ± 0.032	6.967SerLeu: 6.967 ± 0.044	1.657SerMet: 1.657 ± 0.02	2.664SerAsn: 2.664 ± 0.023	4.769SerPro: 4.769 ± 0.044	3.092SerGln: 3.092 ± 0.03	4.81SerArg: 4.81 ± 0.039	7.852SerSer: 7.852 ± 0.08	4.915SerThr: 4.915 ± 0.052	4.538SerVal: 4.538 ± 0.028	1.074SerTrp: 1.074 ± 0.015	1.866SerTyr: 1.866 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.674ThrAla: 5.674 ± 0.037	0.685ThrCys: 0.685 ± 0.011	2.823ThrAsp: 2.823 ± 0.024	2.981ThrGlu: 2.981 ± 0.022	2.111ThrPhe: 2.111 ± 0.019	4.16ThrGly: 4.16 ± 0.045	1.243ThrHis: 1.243 ± 0.016	2.874ThrIle: 2.874 ± 0.026	2.381ThrLys: 2.381 ± 0.021	5.479ThrLeu: 5.479 ± 0.03	1.219ThrMet: 1.219 ± 0.012	1.924ThrAsn: 1.924 ± 0.017	4.046ThrPro: 4.046 ± 0.037	2.082ThrGln: 2.082 ± 0.021	3.196ThrArg: 3.196 ± 0.022	4.718ThrSer: 4.718 ± 0.041	4.214ThrThr: 4.214 ± 0.046	3.837ThrVal: 3.837 ± 0.038	0.809ThrTrp: 0.809 ± 0.012	1.412ThrTyr: 1.412 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	6.315ValAla: 6.315 ± 0.036	0.851ValCys: 0.851 ± 0.013	3.851ValAsp: 3.851 ± 0.029	3.785ValGlu: 3.785 ± 0.027	2.451ValPhe: 2.451 ± 0.023	4.209ValGly: 4.209 ± 0.031	1.391ValHis: 1.391 ± 0.014	3.041ValIle: 3.041 ± 0.026	2.792ValLys: 2.792 ± 0.024	5.896ValLeu: 5.896 ± 0.043	1.464ValMet: 1.464 ± 0.019	2.226ValAsn: 2.226 ± 0.02	3.566ValPro: 3.566 ± 0.038	2.434ValGln: 2.434 ± 0.024	3.582ValArg: 3.582 ± 0.029	4.556ValSer: 4.556 ± 0.026	3.641ValThr: 3.641 ± 0.036	4.667ValVal: 4.667 ± 0.033	0.884ValTrp: 0.884 ± 0.013	1.699ValTyr: 1.699 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.171TrpAla: 1.171 ± 0.015	0.186TrpCys: 0.186 ± 0.006	0.833TrpAsp: 0.833 ± 0.013	0.747TrpGlu: 0.747 ± 0.011	0.536TrpPhe: 0.536 ± 0.008	0.894TrpGly: 0.894 ± 0.013	0.381TrpHis: 0.381 ± 0.009	0.701TrpIle: 0.701 ± 0.01	0.696TrpLys: 0.696 ± 0.012	1.515TrpLeu: 1.515 ± 0.015	0.362TrpMet: 0.362 ± 0.007	0.576TrpAsn: 0.576 ± 0.011	0.643TrpPro: 0.643 ± 0.01	0.692TrpGln: 0.692 ± 0.012	0.983TrpArg: 0.983 ± 0.013	0.996TrpSer: 0.996 ± 0.013	0.84TrpThr: 0.84 ± 0.013	0.857TrpVal: 0.857 ± 0.011	0.265TrpTrp: 0.265 ± 0.006	0.416TrpTyr: 0.416 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.277TyrAla: 2.277 ± 0.025	0.388TyrCys: 0.388 ± 0.009	1.615TyrAsp: 1.615 ± 0.017	1.372TyrGlu: 1.372 ± 0.014	1.101TyrPhe: 1.101 ± 0.014	2.04TyrGly: 2.04 ± 0.024	0.715TyrHis: 0.715 ± 0.011	1.304TyrIle: 1.304 ± 0.016	1.076TyrLys: 1.076 ± 0.015	2.51TyrLeu: 2.51 ± 0.022	0.62TyrMet: 0.62 ± 0.012	1.05TyrAsn: 1.05 ± 0.016	1.329TyrPro: 1.329 ± 0.016	1.124TyrGln: 1.124 ± 0.013	1.6TyrArg: 1.6 ± 0.016	1.862TyrSer: 1.862 ± 0.021	1.514TyrThr: 1.514 ± 0.019	1.575TyrVal: 1.575 ± 0.017	0.422TyrTrp: 0.422 ± 0.01	0.88TyrTyr: 0.88 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11860 proteins (5904528 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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