Amino acid dipepetide frequency for Georgenia soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.468AlaAla: 22.468 ± 0.255	0.808AlaCys: 0.808 ± 0.028	8.516AlaAsp: 8.516 ± 0.098	9.095AlaGlu: 9.095 ± 0.127	3.275AlaPhe: 3.275 ± 0.053	14.509AlaGly: 14.509 ± 0.127	2.584AlaHis: 2.584 ± 0.048	3.637AlaIle: 3.637 ± 0.065	2.001AlaLys: 2.001 ± 0.048	14.17AlaLeu: 14.17 ± 0.135	2.749AlaMet: 2.749 ± 0.045	1.913AlaAsn: 1.913 ± 0.039	7.483AlaPro: 7.483 ± 0.12	3.729AlaGln: 3.729 ± 0.066	11.012AlaArg: 11.012 ± 0.119	6.149AlaSer: 6.149 ± 0.074	7.991AlaThr: 7.991 ± 0.098	13.769AlaVal: 13.769 ± 0.134	1.959AlaTrp: 1.959 ± 0.042	2.234AlaTyr: 2.234 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.704CysAla: 0.704 ± 0.023	0.059CysCys: 0.059 ± 0.007	0.311CysAsp: 0.311 ± 0.016	0.315CysGlu: 0.315 ± 0.014	0.164CysPhe: 0.164 ± 0.013	0.66CysGly: 0.66 ± 0.027	0.132CysHis: 0.132 ± 0.01	0.156CysIle: 0.156 ± 0.013	0.06CysLys: 0.06 ± 0.007	0.5CysLeu: 0.5 ± 0.019	0.083CysMet: 0.083 ± 0.008	0.094CysAsn: 0.094 ± 0.009	0.353CysPro: 0.353 ± 0.019	0.117CysGln: 0.117 ± 0.01	0.392CysArg: 0.392 ± 0.02	0.302CysSer: 0.302 ± 0.015	0.375CysThr: 0.375 ± 0.018	0.441CysVal: 0.441 ± 0.02	0.083CysTrp: 0.083 ± 0.008	0.11CysTyr: 0.11 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	8.408AspAla: 8.408 ± 0.096	0.236AspCys: 0.236 ± 0.015	4.166AspAsp: 4.166 ± 0.082	4.101AspGlu: 4.101 ± 0.061	1.378AspPhe: 1.378 ± 0.04	6.769AspGly: 6.769 ± 0.08	1.405AspHis: 1.405 ± 0.034	1.713AspIle: 1.713 ± 0.04	0.837AspLys: 0.837 ± 0.029	6.644AspLeu: 6.644 ± 0.068	0.789AspMet: 0.789 ± 0.026	0.842AspAsn: 0.842 ± 0.026	4.402AspPro: 4.402 ± 0.061	1.556AspGln: 1.556 ± 0.042	4.575AspArg: 4.575 ± 0.065	2.134AspSer: 2.134 ± 0.037	2.623AspThr: 2.623 ± 0.048	6.572AspVal: 6.572 ± 0.081	0.786AspTrp: 0.786 ± 0.032	1.092AspTyr: 1.092 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	7.713GluAla: 7.713 ± 0.1	0.238GluCys: 0.238 ± 0.013	3.272GluAsp: 3.272 ± 0.063	4.105GluGlu: 4.105 ± 0.074	1.228GluPhe: 1.228 ± 0.035	4.352GluGly: 4.352 ± 0.067	1.81GluHis: 1.81 ± 0.037	2.393GluIle: 2.393 ± 0.049	1.262GluLys: 1.262 ± 0.039	6.884GluLeu: 6.884 ± 0.087	1.0GluMet: 1.0 ± 0.03	1.175GluAsn: 1.175 ± 0.035	3.544GluPro: 3.544 ± 0.06	2.31GluGln: 2.31 ± 0.051	5.54GluArg: 5.54 ± 0.09	2.451GluSer: 2.451 ± 0.041	2.961GluThr: 2.961 ± 0.047	5.468GluVal: 5.468 ± 0.064	0.723GluTrp: 0.723 ± 0.024	0.98GluTyr: 0.98 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.306PheAla: 3.306 ± 0.058	0.175PheCys: 0.175 ± 0.011	1.792PheAsp: 1.792 ± 0.046	1.42PheGlu: 1.42 ± 0.036	0.874PhePhe: 0.874 ± 0.03	2.68PheGly: 2.68 ± 0.052	0.506PheHis: 0.506 ± 0.022	0.721PheIle: 0.721 ± 0.027	0.342PheLys: 0.342 ± 0.016	2.518PheLeu: 2.518 ± 0.049	0.403PheMet: 0.403 ± 0.019	0.486PheAsn: 0.486 ± 0.022	1.276PhePro: 1.276 ± 0.034	0.601PheGln: 0.601 ± 0.02	1.568PheArg: 1.568 ± 0.033	1.475PheSer: 1.475 ± 0.038	1.829PheThr: 1.829 ± 0.035	2.521PheVal: 2.521 ± 0.047	0.388PheTrp: 0.388 ± 0.018	0.586PheTyr: 0.586 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	12.409GlyAla: 12.409 ± 0.125	0.583GlyCys: 0.583 ± 0.024	5.031GlyAsp: 5.031 ± 0.075	5.524GlyGlu: 5.524 ± 0.08	2.615GlyPhe: 2.615 ± 0.045	8.65GlyGly: 8.65 ± 0.106	2.099GlyHis: 2.099 ± 0.04	3.416GlyIle: 3.416 ± 0.06	1.863GlyLys: 1.863 ± 0.042	9.303GlyLeu: 9.303 ± 0.112	2.115GlyMet: 2.115 ± 0.041	1.569GlyAsn: 1.569 ± 0.04	5.282GlyPro: 5.282 ± 0.072	2.766GlyGln: 2.766 ± 0.059	7.821GlyArg: 7.821 ± 0.085	5.2GlySer: 5.2 ± 0.079	6.656GlyThr: 6.656 ± 0.078	8.427GlyVal: 8.427 ± 0.072	1.704GlyTrp: 1.704 ± 0.039	2.129GlyTyr: 2.129 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.592HisAla: 2.592 ± 0.043	0.131HisCys: 0.131 ± 0.011	1.504HisAsp: 1.504 ± 0.042	1.3HisGlu: 1.3 ± 0.033	0.454HisPhe: 0.454 ± 0.019	2.267HisGly: 2.267 ± 0.043	0.667HisHis: 0.667 ± 0.027	0.512HisIle: 0.512 ± 0.019	0.272HisLys: 0.272 ± 0.013	2.517HisLeu: 2.517 ± 0.048	0.302HisMet: 0.302 ± 0.016	0.342HisAsn: 0.342 ± 0.016	1.54HisPro: 1.54 ± 0.039	0.529HisGln: 0.529 ± 0.023	1.795HisArg: 1.795 ± 0.042	0.833HisSer: 0.833 ± 0.029	1.036HisThr: 1.036 ± 0.029	2.046HisVal: 2.046 ± 0.042	0.275HisTrp: 0.275 ± 0.016	0.411HisTyr: 0.411 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	4.344IleAla: 4.344 ± 0.071	0.196IleCys: 0.196 ± 0.013	2.273IleAsp: 2.273 ± 0.047	1.851IleGlu: 1.851 ± 0.044	0.953IlePhe: 0.953 ± 0.034	3.251IleGly: 3.251 ± 0.062	0.532IleHis: 0.532 ± 0.02	1.02IleIle: 1.02 ± 0.035	0.55IleLys: 0.55 ± 0.024	2.69IleLeu: 2.69 ± 0.053	0.49IleMet: 0.49 ± 0.021	0.652IleAsn: 0.652 ± 0.024	1.573IlePro: 1.573 ± 0.043	0.651IleGln: 0.651 ± 0.024	1.855IleArg: 1.855 ± 0.035	1.712IleSer: 1.712 ± 0.041	2.046IleThr: 2.046 ± 0.043	3.192IleVal: 3.192 ± 0.06	0.343IleTrp: 0.343 ± 0.014	0.618IleTyr: 0.618 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	1.956LysAla: 1.956 ± 0.047	0.063LysCys: 0.063 ± 0.008	1.018LysAsp: 1.018 ± 0.031	0.946LysGlu: 0.946 ± 0.028	0.393LysPhe: 0.393 ± 0.018	1.295LysGly: 1.295 ± 0.035	0.354LysHis: 0.354 ± 0.017	0.753LysIle: 0.753 ± 0.024	0.55LysLys: 0.55 ± 0.027	1.415LysLeu: 1.415 ± 0.039	0.334LysMet: 0.334 ± 0.014	0.419LysAsn: 0.419 ± 0.022	0.802LysPro: 0.802 ± 0.031	0.521LysGln: 0.521 ± 0.023	1.027LysArg: 1.027 ± 0.033	0.766LysSer: 0.766 ± 0.026	0.875LysThr: 0.875 ± 0.027	1.68LysVal: 1.68 ± 0.043	0.178LysTrp: 0.178 ± 0.011	0.346LysTyr: 0.346 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	15.942LeuAla: 15.942 ± 0.157	0.569LeuCys: 0.569 ± 0.025	6.793LeuAsp: 6.793 ± 0.085	5.455LeuGlu: 5.455 ± 0.083	2.283LeuPhe: 2.283 ± 0.048	9.979LeuGly: 9.979 ± 0.113	1.989LeuHis: 1.989 ± 0.045	2.668LeuIle: 2.668 ± 0.058	1.349LeuLys: 1.349 ± 0.037	10.867LeuLeu: 10.867 ± 0.136	1.599LeuMet: 1.599 ± 0.039	1.538LeuAsn: 1.538 ± 0.035	6.085LeuPro: 6.085 ± 0.07	2.341LeuGln: 2.341 ± 0.044	8.18LeuArg: 8.18 ± 0.103	5.05LeuSer: 5.05 ± 0.06	6.702LeuThr: 6.702 ± 0.081	10.493LeuVal: 10.493 ± 0.098	1.191LeuTrp: 1.191 ± 0.038	1.574LeuTyr: 1.574 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.301MetAla: 2.301 ± 0.046	0.105MetCys: 0.105 ± 0.01	0.884MetAsp: 0.884 ± 0.028	0.716MetGlu: 0.716 ± 0.021	0.469MetPhe: 0.469 ± 0.022	1.42MetGly: 1.42 ± 0.035	0.322MetHis: 0.322 ± 0.016	0.663MetIle: 0.663 ± 0.025	0.335MetLys: 0.335 ± 0.017	1.812MetLeu: 1.812 ± 0.043	0.277MetMet: 0.277 ± 0.015	0.412MetAsn: 0.412 ± 0.02	1.059MetPro: 1.059 ± 0.032	0.407MetGln: 0.407 ± 0.017	1.409MetArg: 1.409 ± 0.032	1.475MetSer: 1.475 ± 0.032	1.712MetThr: 1.712 ± 0.036	1.599MetVal: 1.599 ± 0.036	0.218MetTrp: 0.218 ± 0.015	0.295MetTyr: 0.295 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	1.98AsnAla: 1.98 ± 0.044	0.09AsnCys: 0.09 ± 0.009	0.972AsnAsp: 0.972 ± 0.026	0.798AsnGlu: 0.798 ± 0.027	0.522AsnPhe: 0.522 ± 0.024	1.582AsnGly: 1.582 ± 0.041	0.403AsnHis: 0.403 ± 0.018	0.639AsnIle: 0.639 ± 0.027	0.3AsnLys: 0.3 ± 0.018	1.859AsnLeu: 1.859 ± 0.043	0.288AsnMet: 0.288 ± 0.015	0.376AsnAsn: 0.376 ± 0.017	1.33AsnPro: 1.33 ± 0.036	0.497AsnGln: 0.497 ± 0.02	1.164AsnArg: 1.164 ± 0.034	0.729AsnSer: 0.729 ± 0.024	0.938AsnThr: 0.938 ± 0.03	1.588AsnVal: 1.588 ± 0.04	0.222AsnTrp: 0.222 ± 0.013	0.367AsnTyr: 0.367 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	9.041ProAla: 9.041 ± 0.122	0.216ProCys: 0.216 ± 0.014	4.453ProAsp: 4.453 ± 0.062	4.293ProGlu: 4.293 ± 0.06	1.504ProPhe: 1.504 ± 0.035	6.629ProGly: 6.629 ± 0.086	1.2ProHis: 1.2 ± 0.033	1.293ProIle: 1.293 ± 0.034	0.751ProLys: 0.751 ± 0.027	4.876ProLeu: 4.876 ± 0.061	0.988ProMet: 0.988 ± 0.026	0.842ProAsn: 0.842 ± 0.028	3.093ProPro: 3.093 ± 0.055	1.525ProGln: 1.525 ± 0.04	3.962ProArg: 3.962 ± 0.064	3.093ProSer: 3.093 ± 0.057	3.636ProThr: 3.636 ± 0.054	5.872ProVal: 5.872 ± 0.085	0.932ProTrp: 0.932 ± 0.028	1.148ProTyr: 1.148 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	3.548GlnAla: 3.548 ± 0.067	0.114GlnCys: 0.114 ± 0.01	1.399GlnAsp: 1.399 ± 0.038	1.458GlnGlu: 1.458 ± 0.033	0.633GlnPhe: 0.633 ± 0.027	2.108GlnGly: 2.108 ± 0.042	0.635GlnHis: 0.635 ± 0.022	1.12GlnIle: 1.12 ± 0.031	0.419GlnLys: 0.419 ± 0.02	3.018GlnLeu: 3.018 ± 0.058	0.536GlnMet: 0.536 ± 0.021	0.515GlnAsn: 0.515 ± 0.021	1.565GlnPro: 1.565 ± 0.041	1.066GlnGln: 1.066 ± 0.032	2.332GlnArg: 2.332 ± 0.049	1.074GlnSer: 1.074 ± 0.027	1.298GlnThr: 1.298 ± 0.04	2.903GlnVal: 2.903 ± 0.056	0.371GlnTrp: 0.371 ± 0.019	0.536GlnTyr: 0.536 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	10.427ArgAla: 10.427 ± 0.122	0.419ArgCys: 0.419 ± 0.019	4.166ArgAsp: 4.166 ± 0.062	4.834ArgGlu: 4.834 ± 0.073	1.991ArgPhe: 1.991 ± 0.042	5.866ArgGly: 5.866 ± 0.08	1.899ArgHis: 1.899 ± 0.045	2.629ArgIle: 2.629 ± 0.047	1.285ArgLys: 1.285 ± 0.039	8.016ArgLeu: 8.016 ± 0.1	1.718ArgMet: 1.718 ± 0.036	1.191ArgAsn: 1.191 ± 0.031	5.072ArgPro: 5.072 ± 0.08	2.187ArgGln: 2.187 ± 0.053	8.346ArgArg: 8.346 ± 0.105	4.23ArgSer: 4.23 ± 0.06	5.41ArgThr: 5.41 ± 0.069	6.37ArgVal: 6.37 ± 0.078	1.457ArgTrp: 1.457 ± 0.039	1.673ArgTyr: 1.673 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.75SerAla: 6.75 ± 0.075	0.269SerCys: 0.269 ± 0.016	2.603SerAsp: 2.603 ± 0.045	2.435SerGlu: 2.435 ± 0.05	1.547SerPhe: 1.547 ± 0.039	5.427SerGly: 5.427 ± 0.065	0.935SerHis: 0.935 ± 0.026	1.477SerIle: 1.477 ± 0.039	0.735SerLys: 0.735 ± 0.028	4.777SerLeu: 4.777 ± 0.065	1.048SerMet: 1.048 ± 0.034	0.844SerAsn: 0.844 ± 0.028	3.077SerPro: 3.077 ± 0.05	1.223SerGln: 1.223 ± 0.036	3.678SerArg: 3.678 ± 0.06	2.908SerSer: 2.908 ± 0.054	3.321SerThr: 3.321 ± 0.06	4.46SerVal: 4.46 ± 0.063	0.917SerTrp: 0.917 ± 0.026	1.094SerTyr: 1.094 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	8.574ThrAla: 8.574 ± 0.09	0.346ThrCys: 0.346 ± 0.016	3.709ThrAsp: 3.709 ± 0.056	3.256ThrGlu: 3.256 ± 0.058	1.919ThrPhe: 1.919 ± 0.044	6.478ThrGly: 6.478 ± 0.069	1.137ThrHis: 1.137 ± 0.027	1.992ThrIle: 1.992 ± 0.042	0.963ThrLys: 0.963 ± 0.028	5.832ThrLeu: 5.832 ± 0.076	1.029ThrMet: 1.029 ± 0.029	1.058ThrAsn: 1.058 ± 0.03	4.006ThrPro: 4.006 ± 0.055	1.41ThrGln: 1.41 ± 0.036	3.921ThrArg: 3.921 ± 0.059	3.426ThrSer: 3.426 ± 0.054	4.475ThrThr: 4.475 ± 0.074	6.392ThrVal: 6.392 ± 0.09	0.998ThrTrp: 0.998 ± 0.027	1.276ThrTyr: 1.276 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	13.575ValAla: 13.575 ± 0.117	0.574ValCys: 0.574 ± 0.019	6.1ValAsp: 6.1 ± 0.065	5.718ValGlu: 5.718 ± 0.068	2.221ValPhe: 2.221 ± 0.051	8.219ValGly: 8.219 ± 0.088	2.02ValHis: 2.02 ± 0.049	3.027ValIle: 3.027 ± 0.055	1.302ValLys: 1.302 ± 0.035	11.197ValLeu: 11.197 ± 0.112	1.602ValMet: 1.602 ± 0.033	1.664ValAsn: 1.664 ± 0.041	6.023ValPro: 6.023 ± 0.073	2.216ValGln: 2.216 ± 0.04	7.692ValArg: 7.692 ± 0.093	4.694ValSer: 4.694 ± 0.061	6.283ValThr: 6.283 ± 0.076	11.473ValVal: 11.473 ± 0.117	1.152ValTrp: 1.152 ± 0.028	1.538ValTyr: 1.538 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.681TrpAla: 1.681 ± 0.038	0.1TrpCys: 0.1 ± 0.009	0.801TrpAsp: 0.801 ± 0.027	0.709TrpGlu: 0.709 ± 0.026	0.493TrpPhe: 0.493 ± 0.019	1.054TrpGly: 1.054 ± 0.032	0.355TrpHis: 0.355 ± 0.018	0.484TrpIle: 0.484 ± 0.021	0.247TrpLys: 0.247 ± 0.015	1.654TrpLeu: 1.654 ± 0.041	0.279TrpMet: 0.279 ± 0.017	0.343TrpAsn: 0.343 ± 0.017	0.763TrpPro: 0.763 ± 0.023	0.49TrpGln: 0.49 ± 0.02	1.302TrpArg: 1.302 ± 0.033	0.909TrpSer: 0.909 ± 0.03	0.936TrpThr: 0.936 ± 0.031	1.265TrpVal: 1.265 ± 0.035	0.392TrpTrp: 0.392 ± 0.018	0.307TrpTyr: 0.307 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.333TyrAla: 2.333 ± 0.046	0.118TyrCys: 0.118 ± 0.009	1.265TyrAsp: 1.265 ± 0.035	1.079TyrGlu: 1.079 ± 0.034	0.55TyrPhe: 0.55 ± 0.022	1.968TyrGly: 1.968 ± 0.049	0.342TyrHis: 0.342 ± 0.018	0.48TyrIle: 0.48 ± 0.019	0.269TyrLys: 0.269 ± 0.016	2.098TyrLeu: 2.098 ± 0.041	0.261TyrMet: 0.261 ± 0.015	0.369TyrAsn: 0.369 ± 0.018	1.02TyrPro: 1.02 ± 0.03	0.503TyrGln: 0.503 ± 0.026	1.613TyrArg: 1.613 ± 0.039	0.914TyrSer: 0.914 ± 0.029	1.094TyrThr: 1.094 ± 0.032	1.759TyrVal: 1.759 ± 0.036	0.28TyrTrp: 0.28 ± 0.016	0.426TyrTyr: 0.426 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3768 proteins (1259096 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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