Amino acid dipepetide frequency for Klebsiella phage ST405-OXA48phi1.2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.556AlaAla: 10.556 ± 0.935
0.655AlaCys: 0.655 ± 0.269
6.301AlaAsp: 6.301 ± 0.768
5.319AlaGlu: 5.319 ± 0.856
3.028AlaPhe: 3.028 ± 0.493
8.592AlaGly: 8.592 ± 0.823
1.227AlaHis: 1.227 ± 0.32
6.71AlaIle: 6.71 ± 1.029
5.483AlaLys: 5.483 ± 0.638
8.511AlaLeu: 8.511 ± 0.873
3.437AlaMet: 3.437 ± 0.571
4.255AlaAsn: 4.255 ± 0.696
2.537AlaPro: 2.537 ± 0.317
3.437AlaGln: 3.437 ± 0.45
4.337AlaArg: 4.337 ± 0.587
6.383AlaSer: 6.383 ± 0.655
5.974AlaThr: 5.974 ± 0.74
6.628AlaVal: 6.628 ± 0.702
1.637AlaTrp: 1.637 ± 0.323
2.619AlaTyr: 2.619 ± 0.518
0.0AlaXaa: 0.0 ± 0.0
Cys
1.227CysAla: 1.227 ± 0.274
0.164CysCys: 0.164 ± 0.094
0.409CysAsp: 0.409 ± 0.206
0.491CysGlu: 0.491 ± 0.192
0.245CysPhe: 0.245 ± 0.136
1.064CysGly: 1.064 ± 0.272
0.327CysHis: 0.327 ± 0.149
1.064CysIle: 1.064 ± 0.34
0.327CysLys: 0.327 ± 0.141
0.9CysLeu: 0.9 ± 0.352
0.245CysMet: 0.245 ± 0.121
0.327CysAsn: 0.327 ± 0.152
0.573CysPro: 0.573 ± 0.247
0.327CysGln: 0.327 ± 0.209
1.064CysArg: 1.064 ± 0.399
0.818CysSer: 0.818 ± 0.282
0.491CysThr: 0.491 ± 0.277
0.245CysVal: 0.245 ± 0.13
0.409CysTrp: 0.409 ± 0.18
0.245CysTyr: 0.245 ± 0.15
0.0CysXaa: 0.0 ± 0.0
Asp
6.628AspAla: 6.628 ± 0.781
0.9AspCys: 0.9 ± 0.305
3.764AspAsp: 3.764 ± 0.492
4.173AspGlu: 4.173 ± 0.541
2.209AspPhe: 2.209 ± 0.386
4.664AspGly: 4.664 ± 0.621
0.573AspHis: 0.573 ± 0.194
3.846AspIle: 3.846 ± 0.44
3.437AspLys: 3.437 ± 0.478
4.746AspLeu: 4.746 ± 0.589
0.9AspMet: 0.9 ± 0.278
2.537AspAsn: 2.537 ± 0.404
2.128AspPro: 2.128 ± 0.438
2.455AspGln: 2.455 ± 0.522
2.619AspArg: 2.619 ± 0.42
4.092AspSer: 4.092 ± 0.509
3.519AspThr: 3.519 ± 0.57
4.746AspVal: 4.746 ± 0.547
1.309AspTrp: 1.309 ± 0.394
1.555AspTyr: 1.555 ± 0.305
0.0AspXaa: 0.0 ± 0.0
Glu
5.237GluAla: 5.237 ± 0.883
0.573GluCys: 0.573 ± 0.202
2.864GluAsp: 2.864 ± 0.471
3.846GluGlu: 3.846 ± 0.781
2.537GluPhe: 2.537 ± 0.523
4.337GluGly: 4.337 ± 0.587
0.736GluHis: 0.736 ± 0.26
3.601GluIle: 3.601 ± 0.494
2.782GluLys: 2.782 ± 0.532
5.155GluLeu: 5.155 ± 0.576
2.291GluMet: 2.291 ± 0.403
2.7GluAsn: 2.7 ± 0.401
2.291GluPro: 2.291 ± 0.453
2.046GluGln: 2.046 ± 0.469
4.255GluArg: 4.255 ± 0.62
4.092GluSer: 4.092 ± 0.66
3.028GluThr: 3.028 ± 0.497
3.273GluVal: 3.273 ± 0.473
1.146GluTrp: 1.146 ± 0.309
0.9GluTyr: 0.9 ± 0.266
0.0GluXaa: 0.0 ± 0.0
Phe
2.782PheAla: 2.782 ± 0.627
0.573PheCys: 0.573 ± 0.216
2.864PheAsp: 2.864 ± 0.518
1.637PheGlu: 1.637 ± 0.341
1.309PhePhe: 1.309 ± 0.262
2.128PheGly: 2.128 ± 0.414
0.409PheHis: 0.409 ± 0.199
1.8PheIle: 1.8 ± 0.412
1.718PheLys: 1.718 ± 0.385
2.782PheLeu: 2.782 ± 0.484
0.655PheMet: 0.655 ± 0.206
1.964PheAsn: 1.964 ± 0.398
1.391PhePro: 1.391 ± 0.318
0.9PheGln: 0.9 ± 0.241
2.128PheArg: 2.128 ± 0.298
2.619PheSer: 2.619 ± 0.36
1.882PheThr: 1.882 ± 0.357
2.537PheVal: 2.537 ± 0.492
1.391PheTrp: 1.391 ± 0.349
1.064PheTyr: 1.064 ± 0.231
0.0PheXaa: 0.0 ± 0.0
Gly
7.201GlyAla: 7.201 ± 0.829
0.736GlyCys: 0.736 ± 0.235
5.483GlyAsp: 5.483 ± 0.775
4.092GlyGlu: 4.092 ± 0.509
3.191GlyPhe: 3.191 ± 0.486
5.728GlyGly: 5.728 ± 0.769
0.982GlyHis: 0.982 ± 0.285
5.319GlyIle: 5.319 ± 0.618
4.91GlyLys: 4.91 ± 0.705
6.056GlyLeu: 6.056 ± 0.734
2.373GlyMet: 2.373 ± 0.466
3.764GlyAsn: 3.764 ± 0.595
2.455GlyPro: 2.455 ± 0.388
2.455GlyGln: 2.455 ± 0.436
4.173GlyArg: 4.173 ± 0.509
4.419GlySer: 4.419 ± 0.658
4.746GlyThr: 4.746 ± 0.685
5.974GlyVal: 5.974 ± 0.64
1.309GlyTrp: 1.309 ± 0.313
2.946GlyTyr: 2.946 ± 0.57
0.0GlyXaa: 0.0 ± 0.0
His
1.8HisAla: 1.8 ± 0.374
0.491HisCys: 0.491 ± 0.202
0.9HisAsp: 0.9 ± 0.277
1.064HisGlu: 1.064 ± 0.286
0.491HisPhe: 0.491 ± 0.203
1.637HisGly: 1.637 ± 0.303
0.491HisHis: 0.491 ± 0.215
0.818HisIle: 0.818 ± 0.22
0.573HisLys: 0.573 ± 0.198
1.555HisLeu: 1.555 ± 0.356
0.409HisMet: 0.409 ± 0.157
0.409HisAsn: 0.409 ± 0.193
0.655HisPro: 0.655 ± 0.218
0.164HisGln: 0.164 ± 0.101
0.9HisArg: 0.9 ± 0.246
0.655HisSer: 0.655 ± 0.24
0.736HisThr: 0.736 ± 0.26
0.982HisVal: 0.982 ± 0.3
0.245HisTrp: 0.245 ± 0.152
0.573HisTyr: 0.573 ± 0.205
0.0HisXaa: 0.0 ± 0.0
Ile
4.419IleAla: 4.419 ± 0.643
1.064IleCys: 1.064 ± 0.383
3.028IleAsp: 3.028 ± 0.418
3.601IleGlu: 3.601 ± 0.59
2.373IlePhe: 2.373 ± 0.43
5.319IleGly: 5.319 ± 0.676
0.736IleHis: 0.736 ± 0.264
2.7IleIle: 2.7 ± 0.366
3.11IleLys: 3.11 ± 0.397
2.864IleLeu: 2.864 ± 0.47
1.882IleMet: 1.882 ± 0.352
3.601IleAsn: 3.601 ± 0.591
3.519IlePro: 3.519 ± 0.496
3.11IleGln: 3.11 ± 0.561
4.01IleArg: 4.01 ± 0.454
4.828IleSer: 4.828 ± 0.54
4.583IleThr: 4.583 ± 0.562
3.028IleVal: 3.028 ± 0.444
0.573IleTrp: 0.573 ± 0.265
1.309IleTyr: 1.309 ± 0.328
0.0IleXaa: 0.0 ± 0.0
Lys
5.646LysAla: 5.646 ± 0.735
0.736LysCys: 0.736 ± 0.265
2.537LysAsp: 2.537 ± 0.443
3.191LysGlu: 3.191 ± 0.52
1.473LysPhe: 1.473 ± 0.301
2.946LysGly: 2.946 ± 0.429
1.064LysHis: 1.064 ± 0.329
3.764LysIle: 3.764 ± 0.62
2.537LysLys: 2.537 ± 0.396
3.846LysLeu: 3.846 ± 0.454
1.391LysMet: 1.391 ± 0.392
2.455LysAsn: 2.455 ± 0.389
2.373LysPro: 2.373 ± 0.453
1.473LysGln: 1.473 ± 0.376
3.11LysArg: 3.11 ± 0.494
3.355LysSer: 3.355 ± 0.527
3.928LysThr: 3.928 ± 0.609
2.7LysVal: 2.7 ± 0.464
0.736LysTrp: 0.736 ± 0.243
1.473LysTyr: 1.473 ± 0.269
0.0LysXaa: 0.0 ± 0.0
Leu
8.511LeuAla: 8.511 ± 0.717
0.573LeuCys: 0.573 ± 0.191
4.337LeuAsp: 4.337 ± 0.529
4.255LeuGlu: 4.255 ± 0.578
2.291LeuPhe: 2.291 ± 0.402
5.319LeuGly: 5.319 ± 0.609
1.473LeuHis: 1.473 ± 0.312
5.155LeuIle: 5.155 ± 0.705
5.155LeuLys: 5.155 ± 0.6
6.628LeuLeu: 6.628 ± 0.694
1.8LeuMet: 1.8 ± 0.417
4.255LeuAsn: 4.255 ± 0.616
3.273LeuPro: 3.273 ± 0.469
2.619LeuGln: 2.619 ± 0.462
4.91LeuArg: 4.91 ± 0.721
6.383LeuSer: 6.383 ± 0.539
4.583LeuThr: 4.583 ± 0.618
5.074LeuVal: 5.074 ± 0.693
1.146LeuTrp: 1.146 ± 0.358
2.455LeuTyr: 2.455 ± 0.468
0.0LeuXaa: 0.0 ± 0.0
Met
3.437MetAla: 3.437 ± 0.592
0.245MetCys: 0.245 ± 0.129
1.064MetAsp: 1.064 ± 0.27
1.146MetGlu: 1.146 ± 0.254
0.982MetPhe: 0.982 ± 0.31
1.227MetGly: 1.227 ± 0.288
0.327MetHis: 0.327 ± 0.158
1.637MetIle: 1.637 ± 0.357
1.637MetLys: 1.637 ± 0.397
1.718MetLeu: 1.718 ± 0.435
0.491MetMet: 0.491 ± 0.188
1.473MetAsn: 1.473 ± 0.361
1.555MetPro: 1.555 ± 0.381
0.818MetGln: 0.818 ± 0.225
1.227MetArg: 1.227 ± 0.301
2.209MetSer: 2.209 ± 0.483
1.555MetThr: 1.555 ± 0.358
1.391MetVal: 1.391 ± 0.328
0.082MetTrp: 0.082 ± 0.084
0.655MetTyr: 0.655 ± 0.238
0.0MetXaa: 0.0 ± 0.0
Asn
3.682AsnAla: 3.682 ± 0.547
0.573AsnCys: 0.573 ± 0.203
2.455AsnAsp: 2.455 ± 0.453
1.8AsnGlu: 1.8 ± 0.435
1.718AsnPhe: 1.718 ± 0.316
5.074AsnGly: 5.074 ± 0.731
0.982AsnHis: 0.982 ± 0.273
2.373AsnIle: 2.373 ± 0.397
1.391AsnLys: 1.391 ± 0.404
3.764AsnLeu: 3.764 ± 0.467
1.391AsnMet: 1.391 ± 0.344
2.619AsnAsn: 2.619 ± 0.408
2.455AsnPro: 2.455 ± 0.391
2.537AsnGln: 2.537 ± 0.383
1.718AsnArg: 1.718 ± 0.325
3.028AsnSer: 3.028 ± 0.585
3.519AsnThr: 3.519 ± 0.49
3.11AsnVal: 3.11 ± 0.678
0.9AsnTrp: 0.9 ± 0.281
1.882AsnTyr: 1.882 ± 0.359
0.0AsnXaa: 0.0 ± 0.0
Pro
4.01ProAla: 4.01 ± 0.513
0.164ProCys: 0.164 ± 0.114
3.928ProAsp: 3.928 ± 0.467
3.682ProGlu: 3.682 ± 0.513
1.146ProPhe: 1.146 ± 0.284
2.619ProGly: 2.619 ± 0.554
0.9ProHis: 0.9 ± 0.269
2.209ProIle: 2.209 ± 0.373
1.637ProLys: 1.637 ± 0.39
3.11ProLeu: 3.11 ± 0.64
0.818ProMet: 0.818 ± 0.275
1.882ProAsn: 1.882 ± 0.454
1.718ProPro: 1.718 ± 0.457
1.964ProGln: 1.964 ± 0.408
1.637ProArg: 1.637 ± 0.352
1.882ProSer: 1.882 ± 0.346
1.964ProThr: 1.964 ± 0.345
4.255ProVal: 4.255 ± 0.726
0.245ProTrp: 0.245 ± 0.127
1.146ProTyr: 1.146 ± 0.234
0.0ProXaa: 0.0 ± 0.0
Gln
4.173GlnAla: 4.173 ± 0.606
0.327GlnCys: 0.327 ± 0.214
1.227GlnAsp: 1.227 ± 0.365
2.209GlnGlu: 2.209 ± 0.496
1.146GlnPhe: 1.146 ± 0.31
2.209GlnGly: 2.209 ± 0.519
1.146GlnHis: 1.146 ± 0.286
1.964GlnIle: 1.964 ± 0.286
1.8GlnLys: 1.8 ± 0.332
4.01GlnLeu: 4.01 ± 0.503
0.655GlnMet: 0.655 ± 0.196
1.718GlnAsn: 1.718 ± 0.311
1.473GlnPro: 1.473 ± 0.333
1.882GlnGln: 1.882 ± 0.354
1.718GlnArg: 1.718 ± 0.425
3.764GlnSer: 3.764 ± 0.482
2.291GlnThr: 2.291 ± 0.397
2.128GlnVal: 2.128 ± 0.462
0.982GlnTrp: 0.982 ± 0.34
1.882GlnTyr: 1.882 ± 0.324
0.0GlnXaa: 0.0 ± 0.0
Arg
4.337ArgAla: 4.337 ± 0.582
0.655ArgCys: 0.655 ± 0.204
3.764ArgAsp: 3.764 ± 0.515
3.437ArgGlu: 3.437 ± 0.535
2.619ArgPhe: 2.619 ± 0.471
3.11ArgGly: 3.11 ± 0.444
1.227ArgHis: 1.227 ± 0.324
3.519ArgIle: 3.519 ± 0.612
3.519ArgLys: 3.519 ± 0.755
4.828ArgLeu: 4.828 ± 0.705
1.555ArgMet: 1.555 ± 0.314
1.8ArgAsn: 1.8 ± 0.368
2.373ArgPro: 2.373 ± 0.41
3.028ArgGln: 3.028 ± 0.534
3.519ArgArg: 3.519 ± 0.642
3.928ArgSer: 3.928 ± 0.543
2.455ArgThr: 2.455 ± 0.416
4.092ArgVal: 4.092 ± 0.545
1.718ArgTrp: 1.718 ± 0.415
1.227ArgTyr: 1.227 ± 0.253
0.0ArgXaa: 0.0 ± 0.0
Ser
7.61SerAla: 7.61 ± 0.886
0.9SerCys: 0.9 ± 0.24
3.682SerAsp: 3.682 ± 0.534
4.746SerGlu: 4.746 ± 0.676
2.046SerPhe: 2.046 ± 0.423
6.792SerGly: 6.792 ± 0.935
1.146SerHis: 1.146 ± 0.379
3.273SerIle: 3.273 ± 0.449
3.764SerLys: 3.764 ± 0.521
6.628SerLeu: 6.628 ± 0.759
1.227SerMet: 1.227 ± 0.318
3.028SerAsn: 3.028 ± 0.458
3.028SerPro: 3.028 ± 0.538
2.291SerGln: 2.291 ± 0.402
4.337SerArg: 4.337 ± 0.641
4.173SerSer: 4.173 ± 0.608
4.092SerThr: 4.092 ± 0.616
4.583SerVal: 4.583 ± 0.805
0.736SerTrp: 0.736 ± 0.2
1.391SerTyr: 1.391 ± 0.417
0.0SerXaa: 0.0 ± 0.0
Thr
5.728ThrAla: 5.728 ± 0.656
0.491ThrCys: 0.491 ± 0.187
4.255ThrAsp: 4.255 ± 0.648
2.946ThrGlu: 2.946 ± 0.486
2.046ThrPhe: 2.046 ± 0.393
6.547ThrGly: 6.547 ± 0.982
0.409ThrHis: 0.409 ± 0.173
3.028ThrIle: 3.028 ± 0.598
2.455ThrLys: 2.455 ± 0.448
4.501ThrLeu: 4.501 ± 0.608
0.9ThrMet: 0.9 ± 0.276
2.864ThrAsn: 2.864 ± 0.526
3.355ThrPro: 3.355 ± 0.529
2.455ThrGln: 2.455 ± 0.588
2.373ThrArg: 2.373 ± 0.452
3.601ThrSer: 3.601 ± 0.576
3.519ThrThr: 3.519 ± 0.738
5.81ThrVal: 5.81 ± 0.938
1.555ThrTrp: 1.555 ± 0.292
1.718ThrTyr: 1.718 ± 0.392
0.0ThrXaa: 0.0 ± 0.0
Val
6.547ValAla: 6.547 ± 1.016
0.491ValCys: 0.491 ± 0.2
4.828ValAsp: 4.828 ± 0.664
3.928ValGlu: 3.928 ± 0.596
1.637ValPhe: 1.637 ± 0.455
4.91ValGly: 4.91 ± 0.588
0.655ValHis: 0.655 ± 0.225
4.501ValIle: 4.501 ± 0.627
2.619ValLys: 2.619 ± 0.396
5.155ValLeu: 5.155 ± 0.587
1.146ValMet: 1.146 ± 0.308
3.519ValAsn: 3.519 ± 0.707
2.373ValPro: 2.373 ± 0.489
2.209ValGln: 2.209 ± 0.479
4.337ValArg: 4.337 ± 0.596
5.401ValSer: 5.401 ± 0.751
5.565ValThr: 5.565 ± 0.892
3.928ValVal: 3.928 ± 0.875
1.227ValTrp: 1.227 ± 0.261
2.7ValTyr: 2.7 ± 0.531
0.0ValXaa: 0.0 ± 0.0
Trp
1.882TrpAla: 1.882 ± 0.394
0.327TrpCys: 0.327 ± 0.144
0.9TrpAsp: 0.9 ± 0.266
1.227TrpGlu: 1.227 ± 0.34
0.818TrpPhe: 0.818 ± 0.245
0.982TrpGly: 0.982 ± 0.255
0.164TrpHis: 0.164 ± 0.094
1.064TrpIle: 1.064 ± 0.286
0.9TrpLys: 0.9 ± 0.223
1.555TrpLeu: 1.555 ± 0.385
0.736TrpMet: 0.736 ± 0.251
0.818TrpAsn: 0.818 ± 0.231
0.327TrpPro: 0.327 ± 0.19
0.818TrpGln: 0.818 ± 0.225
1.146TrpArg: 1.146 ± 0.329
1.555TrpSer: 1.555 ± 0.354
0.655TrpThr: 0.655 ± 0.238
1.309TrpVal: 1.309 ± 0.338
0.655TrpTrp: 0.655 ± 0.201
0.655TrpTyr: 0.655 ± 0.248
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.291TyrAla: 2.291 ± 0.514
0.327TyrCys: 0.327 ± 0.158
2.209TyrAsp: 2.209 ± 0.506
0.9TyrGlu: 0.9 ± 0.271
1.227TyrPhe: 1.227 ± 0.286
3.11TyrGly: 3.11 ± 0.555
0.573TyrHis: 0.573 ± 0.209
1.309TyrIle: 1.309 ± 0.306
0.982TyrLys: 0.982 ± 0.264
1.882TyrLeu: 1.882 ± 0.418
0.491TyrMet: 0.491 ± 0.171
0.982TyrAsn: 0.982 ± 0.301
1.064TyrPro: 1.064 ± 0.279
1.718TyrGln: 1.718 ± 0.413
3.191TyrArg: 3.191 ± 0.397
2.291TyrSer: 2.291 ± 0.45
1.473TyrThr: 1.473 ± 0.26
1.882TyrVal: 1.882 ± 0.541
0.491TyrTrp: 0.491 ± 0.186
1.146TyrTyr: 1.146 ± 0.346
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 66 proteins (12221 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski