Strongylocentrotus purpuratus (Purple sea urchin)
Average proteome isoelectric point is 6.29
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 34423 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A7M7NH22|A0A7M7NH22_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
MM1 pKa = 7.7 LGQKK5 pKa = 7.61 VHH7 pKa = 7.11 PFRR10 pKa = 11.84 ASHH13 pKa = 6.78 PPRR16 pKa = 11.84 TLLHH20 pKa = 5.36 QVQDD24 pKa = 3.33 KK25 pKa = 10.41 TDD27 pKa = 3.4 AFKK30 pKa = 10.49 MISKK34 pKa = 8.73 TLGLSGPHH42 pKa = 6.36 PVLPKK47 pKa = 10.65 DD48 pKa = 3.53 NQTVFQKK55 pKa = 11.04 DD56 pKa = 3.83 HH57 pKa = 7.53 LSMINQKK64 pKa = 9.63 CQNPCEE70 pKa = 4.42 PNPCLNQGACSGSIGNTTFTCVCTAGFSGQNCGTDD105 pKa = 3.05 RR106 pKa = 11.84 ASNDD110 pKa = 2.9 APQFVYY116 pKa = 9.5 TQDD119 pKa = 3.31 PTLKK123 pKa = 8.77 VTEE126 pKa = 4.39 GQSPSIVVFTLNATDD141 pKa = 4.36 PDD143 pKa = 4.37 GDD145 pKa = 4.52 LIIYY149 pKa = 10.18 DD150 pKa = 4.71 LFDD153 pKa = 4.43 DD154 pKa = 4.58 AARR157 pKa = 11.84 SIFAINQFTGQLYY170 pKa = 10.33 ASPGLDD176 pKa = 3.17 YY177 pKa = 11.5 EE178 pKa = 4.38 MLGNQVIITVSVTDD192 pKa = 5.17 GINDD196 pKa = 3.9 PVPQTIYY203 pKa = 10.99 VQITDD208 pKa = 3.95 VNDD211 pKa = 3.36 IAPTFTNLPNITYY224 pKa = 9.59 VFEE227 pKa = 4.14 NATIGSEE234 pKa = 4.54 LYY236 pKa = 10.28 QVITTDD242 pKa = 2.78 EE243 pKa = 4.05 DD244 pKa = 3.76 TFYY247 pKa = 11.36 GGFVTYY253 pKa = 10.45 SILLVTPSNPGSAPNNYY270 pKa = 9.31 FSIGEE275 pKa = 4.02 TDD277 pKa = 5.05 GIIQLATSLNYY288 pKa = 10.3 EE289 pKa = 4.65 EE290 pKa = 4.22 IQQYY294 pKa = 9.18 FVTVVARR301 pKa = 11.84 DD302 pKa = 3.66 YY303 pKa = 10.7 GTGDD307 pKa = 3.3 TSLSSTATLTVSVLDD322 pKa = 3.86 IQDD325 pKa = 3.76 TNPVFLNIPYY335 pKa = 10.38 DD336 pKa = 3.61 VTIPEE341 pKa = 4.34 TLPVGSTVQTIRR353 pKa = 11.84 ATDD356 pKa = 3.79 PDD358 pKa = 4.57 TNNGNIITYY367 pKa = 9.81 NLVVSDD373 pKa = 3.66 SQGYY377 pKa = 7.92 FVIDD381 pKa = 3.34 QTTGIITVNSQMDD394 pKa = 3.76 RR395 pKa = 11.84 DD396 pKa = 4.23 NPVLPATYY404 pKa = 9.28 PLIVSAVEE412 pKa = 4.02 TSSGGVSFAQVSFNVTVSPANDD434 pKa = 3.56 EE435 pKa = 4.46 PPSFDD440 pKa = 3.37 QNSYY444 pKa = 9.93 SASIPEE450 pKa = 4.11 SASINSQLPITITVDD465 pKa = 3.48 DD466 pKa = 5.07 GDD468 pKa = 5.72 LITDD472 pKa = 3.61 STVTVSLQNGNSVPFRR488 pKa = 11.84 VSPTQVVGSGTIDD501 pKa = 3.19 ILITQPLDD509 pKa = 3.33 FEE511 pKa = 5.75 NNQQYY516 pKa = 8.34 TLQLQAVDD524 pKa = 5.25 GDD526 pKa = 4.44 GQDD529 pKa = 3.84 LAPLMVTVTDD539 pKa = 3.91 VNDD542 pKa = 3.6 NNPVFINRR550 pKa = 11.84 PIDD553 pKa = 3.73 NIYY556 pKa = 10.33 RR557 pKa = 11.84 GSINEE562 pKa = 3.81 NDD564 pKa = 3.4 QTGTFIVQVSTTDD577 pKa = 3.35 ADD579 pKa = 3.94 SGSNAAVTYY588 pKa = 10.16 SIISGNINNVFTINPTSGAITNTQILGPNTPQTYY622 pKa = 8.14 TLSVRR627 pKa = 11.84 ATNPTPGVAPATGTSTSTVIITVNDD652 pKa = 3.7 VNDD655 pKa = 3.74 SPPRR659 pKa = 11.84 FSDD662 pKa = 3.09 NEE664 pKa = 3.96 YY665 pKa = 9.53 TVFINEE671 pKa = 4.02 AAQVGTTVTRR681 pKa = 11.84 ITATDD686 pKa = 3.3 EE687 pKa = 4.94 DD688 pKa = 4.37 IPEE691 pKa = 4.48 GDD693 pKa = 3.55 RR694 pKa = 11.84 LTYY697 pKa = 10.24 IITAGNQGGHH707 pKa = 5.11 FQINPVSGDD716 pKa = 3.43 VTLLRR721 pKa = 11.84 QLDD724 pKa = 3.91 RR725 pKa = 11.84 EE726 pKa = 4.58 LEE728 pKa = 4.28 SQHH731 pKa = 6.24 NLTIRR736 pKa = 11.84 ATDD739 pKa = 3.17 QGAPPQSATTTLKK752 pKa = 11.1 VIVLDD757 pKa = 4.43 FNDD760 pKa = 5.53 NAPQWNPQSYY770 pKa = 10.37 VDD772 pKa = 4.93 SILEE776 pKa = 3.97 NVPVNTFVLQVVATDD791 pKa = 3.71 NDD793 pKa = 3.33 QGTNADD799 pKa = 4.11 LSFTINNANNVPFVIDD815 pKa = 3.51 DD816 pKa = 3.41 QGNIRR821 pKa = 11.84 TSGPLNRR828 pKa = 11.84 EE829 pKa = 3.63 TVPQYY834 pKa = 11.46 NFLVTVLDD842 pKa = 3.93 NGSPQQAGNPPATITINILDD862 pKa = 4.34 VNDD865 pKa = 4.14 EE866 pKa = 4.33 PPVLDD871 pKa = 3.7 RR872 pKa = 11.84 NAYY875 pKa = 9.02 EE876 pKa = 4.16 FTGSEE881 pKa = 3.95 DD882 pKa = 3.48 VNFNTFVGQVTATDD896 pKa = 4.17 PDD898 pKa = 3.64 LSGTLTYY905 pKa = 10.47 TFVPADD911 pKa = 3.59 PDD913 pKa = 3.7 FNYY916 pKa = 10.03 ISGTIRR922 pKa = 11.84 TNTQLDD928 pKa = 3.66 ANQQQVYY935 pKa = 9.32 QMTVFASDD943 pKa = 3.92 GVQNSQSAPVTINVLDD959 pKa = 4.37 VNTQAPFFGLGTYY972 pKa = 9.46 VKK974 pKa = 9.96 SLPEE978 pKa = 4.34 DD979 pKa = 3.56 SPFQTLVVDD988 pKa = 5.97 LNATDD993 pKa = 4.61 PDD995 pKa = 3.69 NGNIGLIIYY1004 pKa = 9.89 SFEE1007 pKa = 4.2 SLSRR1011 pKa = 11.84 TQGPFTVEE1019 pKa = 4.29 PYY1021 pKa = 10.13 TGVIDD1026 pKa = 4.05 ISTTAGLDD1034 pKa = 3.15 RR1035 pKa = 11.84 EE1036 pKa = 4.56 TQDD1039 pKa = 3.48 EE1040 pKa = 4.61 YY1041 pKa = 11.5 TMIVIAVDD1049 pKa = 3.78 QPVSGQPMTGTATVSVIVTDD1069 pKa = 4.06 VNDD1072 pKa = 3.54 NAPTFRR1078 pKa = 11.84 DD1079 pKa = 3.02 ISYY1082 pKa = 9.62 EE1083 pKa = 3.77 KK1084 pKa = 10.65 SIFEE1088 pKa = 3.9 NHH1090 pKa = 6.87 PLGSNILTVQADD1102 pKa = 3.95 DD1103 pKa = 4.93 LDD1105 pKa = 5.33 LGVNAVVLYY1114 pKa = 10.2 RR1115 pKa = 11.84 IISGNNNNLFNVDD1128 pKa = 3.01 GQGNINLGNTPLDD1141 pKa = 3.69 RR1142 pKa = 11.84 EE1143 pKa = 4.25 MQDD1146 pKa = 2.97 QYY1148 pKa = 11.93 FLIVQAYY1155 pKa = 9.95 NSDD1158 pKa = 3.49 LSVGTNEE1165 pKa = 4.2 APVIIIILDD1174 pKa = 3.64 INDD1177 pKa = 3.6 VTPLFQQQNYY1187 pKa = 8.34 YY1188 pKa = 10.64 RR1189 pKa = 11.84 PDD1191 pKa = 3.31 LSEE1194 pKa = 4.47 NSPSGTPVLQVFAQDD1209 pKa = 3.32 QDD1211 pKa = 3.66 LDD1213 pKa = 4.03 LAGDD1217 pKa = 3.68 VQYY1220 pKa = 11.76 SLIGNPNFLTINSDD1234 pKa = 3.38 TGVISVNGPIADD1246 pKa = 3.96 LSGSRR1251 pKa = 11.84 NFTMTVRR1258 pKa = 11.84 ATDD1261 pKa = 3.26 QASPFLRR1268 pKa = 11.84 GMATVTVTVVDD1279 pKa = 3.94 DD1280 pKa = 3.99 TVTIPIFTLSRR1291 pKa = 11.84 YY1292 pKa = 7.59 PATVNEE1298 pKa = 4.55 NVNADD1303 pKa = 3.81 TPVTRR1308 pKa = 11.84 VSATLNGNPAGITYY1322 pKa = 10.3 AIDD1325 pKa = 3.91 PNASPAVLEE1334 pKa = 3.92 IFKK1337 pKa = 10.42 IEE1339 pKa = 4.34 EE1340 pKa = 4.15 NTGHH1344 pKa = 6.55 ITTEE1348 pKa = 3.94 GAIDD1352 pKa = 3.74 RR1353 pKa = 11.84 EE1354 pKa = 4.39 VEE1356 pKa = 3.79 DD1357 pKa = 5.81 FYY1359 pKa = 11.73 AFTVFAYY1366 pKa = 10.31 HH1367 pKa = 7.12 EE1368 pKa = 4.88 DD1369 pKa = 3.67 SVAPGSTSVWVNILDD1384 pKa = 4.24 EE1385 pKa = 4.63 NDD1387 pKa = 3.71 NPPEE1391 pKa = 4.68 FITVPPSPVSVQEE1404 pKa = 4.02 NTGGNVPVGVFRR1416 pKa = 11.84 ATDD1419 pKa = 3.51 PDD1421 pKa = 3.64 AGINAQMTFTISGAGSNFFNVFQTAYY1447 pKa = 9.74 GGGTIVVTSPLDD1459 pKa = 3.35 RR1460 pKa = 11.84 EE1461 pKa = 4.23 RR1462 pKa = 11.84 QDD1464 pKa = 4.54 FYY1466 pKa = 11.6 QLTVTATDD1474 pKa = 3.52 GGNPSLSSSFPLNITVTDD1492 pKa = 3.68 VNDD1495 pKa = 4.05 NYY1497 pKa = 10.63 PIWTRR1502 pKa = 11.84 NVYY1505 pKa = 9.99 EE1506 pKa = 4.4 GSINEE1511 pKa = 4.26 NNFTSNPIITVMVNDD1526 pKa = 4.9 LDD1528 pKa = 4.79 LPSSNNFEE1536 pKa = 4.18 YY1537 pKa = 10.7 SIIAGDD1543 pKa = 3.67 PMGMFEE1549 pKa = 4.51 INSNGEE1555 pKa = 3.85 ITVSSLLDD1563 pKa = 3.33 RR1564 pKa = 11.84 EE1565 pKa = 4.27 QQEE1568 pKa = 4.95 TYY1570 pKa = 10.8 QLTIEE1575 pKa = 5.87 LIDD1578 pKa = 3.74 QTNSPPARR1586 pKa = 11.84 TTTLAIITVGDD1597 pKa = 3.98 EE1598 pKa = 4.21 NDD1600 pKa = 3.27 NTPIFDD1606 pKa = 3.6 EE1607 pKa = 4.3 TVIRR1611 pKa = 11.84 VDD1613 pKa = 3.42 VTEE1616 pKa = 5.22 GPSSQNIPVYY1626 pKa = 10.12 MLTANDD1632 pKa = 3.58 IDD1634 pKa = 4.39 LGLNRR1639 pKa = 11.84 DD1640 pKa = 3.59 IIYY1643 pKa = 10.39 AIGSQQPQSHH1653 pKa = 5.44 FQINIVTGMISTTTALDD1670 pKa = 3.17 WEE1672 pKa = 4.9 TISEE1676 pKa = 4.21 YY1677 pKa = 10.68 TLIVTATDD1685 pKa = 3.42 QSPTEE1690 pKa = 4.22 PRR1692 pKa = 11.84 TGTATVIVSVNDD1704 pKa = 3.61 INDD1707 pKa = 4.17 GAPMFVRR1714 pKa = 11.84 DD1715 pKa = 3.58 VYY1717 pKa = 11.18 GPYY1720 pKa = 10.27 SVVEE1724 pKa = 4.25 EE1725 pKa = 4.37 VSNSYY1730 pKa = 10.32 IDD1732 pKa = 4.12 SFQATDD1738 pKa = 3.52 TDD1740 pKa = 3.39 QGQAGTVTYY1749 pKa = 10.09 HH1750 pKa = 7.34 VIGQYY1755 pKa = 11.27 SNLFFIQPQTGVLTIRR1771 pKa = 11.84 PDD1773 pKa = 3.02 RR1774 pKa = 11.84 ALNYY1778 pKa = 7.52 EE1779 pKa = 4.59 TITQFNITVVAMDD1792 pKa = 3.97 MGNPVLSSSTVVGINVININDD1813 pKa = 3.69 HH1814 pKa = 5.2 TPIFEE1819 pKa = 4.95 GIPYY1823 pKa = 9.35 TITLSKK1829 pKa = 10.56 NISAGSLAYY1838 pKa = 9.81 VVRR1841 pKa = 11.84 ATDD1844 pKa = 3.52 DD1845 pKa = 3.44 DD1846 pKa = 4.44 AGIFGEE1852 pKa = 4.31 VRR1854 pKa = 11.84 YY1855 pKa = 10.21 QITDD1859 pKa = 3.2 GNTDD1863 pKa = 3.55 NIFRR1867 pKa = 11.84 IDD1869 pKa = 3.48 QTTGEE1874 pKa = 4.39 VFVQGLLEE1882 pKa = 4.34 TGTYY1886 pKa = 9.88 RR1887 pKa = 11.84 LVVEE1891 pKa = 5.15 ARR1893 pKa = 11.84 DD1894 pKa = 3.89 TPGDD1898 pKa = 3.73 IPSSRR1903 pKa = 11.84 ASSTTLTIVVTDD1915 pKa = 3.93 IGDD1918 pKa = 4.21 FAPTFPGSSLFTGNVFEE1935 pKa = 4.81 NSPVGQPITMIPPIRR1950 pKa = 11.84 AINSDD1955 pKa = 2.9 ATGQLVYY1962 pKa = 10.31 TITGPDD1968 pKa = 3.27 SQTFMINQLSAGIQVNGPLDD1988 pKa = 4.18 RR1989 pKa = 11.84 EE1990 pKa = 4.3 TKK1992 pKa = 10.24 DD1993 pKa = 3.48 FYY1995 pKa = 10.66 EE1996 pKa = 4.26 FRR1998 pKa = 11.84 VIVTDD2003 pKa = 3.55 SMGMTAEE2010 pKa = 4.29 GTVHH2014 pKa = 7.1 INVLDD2019 pKa = 4.08 VNDD2022 pKa = 4.69 FAPAFNDD2029 pKa = 3.14 SVYY2032 pKa = 11.21 NFTIPEE2038 pKa = 4.04 NSPGGYY2044 pKa = 9.5 YY2045 pKa = 10.43 VGGVTAYY2052 pKa = 10.53 DD2053 pKa = 3.75 LDD2055 pKa = 4.47 GDD2057 pKa = 4.02 NVNFFIQTGGEE2068 pKa = 4.05 DD2069 pKa = 3.25 KK2070 pKa = 10.97 FDD2072 pKa = 3.35 IGGTSEE2078 pKa = 4.79 TITVTPGAVLDD2089 pKa = 4.11 RR2090 pKa = 11.84 EE2091 pKa = 4.3 EE2092 pKa = 4.48 KK2093 pKa = 10.35 PFYY2096 pKa = 9.72 TLTVMVSDD2104 pKa = 4.84 LRR2106 pKa = 11.84 NPPLSGTATVYY2117 pKa = 10.82 INLIDD2122 pKa = 4.86 INDD2125 pKa = 3.98 SPPKK2129 pKa = 9.32 FTASFLDD2136 pKa = 3.83 QIISIPEE2143 pKa = 3.89 DD2144 pKa = 3.68 TPGNTLVTAVTATDD2158 pKa = 4.45 DD2159 pKa = 4.7 DD2160 pKa = 4.76 LNSNINYY2167 pKa = 9.69 RR2168 pKa = 11.84 IVSVSVYY2175 pKa = 10.95 DD2176 pKa = 4.08 EE2177 pKa = 5.22 DD2178 pKa = 5.79 DD2179 pKa = 3.46 VDD2181 pKa = 3.38 ITSFFDD2187 pKa = 3.25 YY2188 pKa = 9.53 RR2189 pKa = 11.84 TVFSLNPTNGNITLTSPVDD2208 pKa = 3.47 RR2209 pKa = 11.84 EE2210 pKa = 4.19 VTEE2213 pKa = 4.25 KK2214 pKa = 10.71 FVFSISARR2222 pKa = 11.84 DD2223 pKa = 3.72 LNSQNPIFGTSQEE2236 pKa = 4.17 NAQVTILITDD2246 pKa = 3.35 INDD2249 pKa = 3.11 NHH2251 pKa = 7.25 PAFQPPGTTFILRR2264 pKa = 11.84 QLPEE2268 pKa = 4.11 SFGAGSPIPGNLLALDD2284 pKa = 4.68 PDD2286 pKa = 4.07 LGLNGKK2292 pKa = 8.61 VMYY2295 pKa = 10.36 IIQDD2299 pKa = 3.49 PSGVPVTIDD2308 pKa = 3.16 QNTGQLTLLVTVDD2321 pKa = 4.84 RR2322 pKa = 11.84 EE2323 pKa = 4.02 QQPWVNLTVLAVDD2336 pKa = 4.28 KK2337 pKa = 8.22 GTPSLNTSIPVYY2349 pKa = 10.91 LEE2351 pKa = 4.72 IIDD2354 pKa = 5.01 NNDD2357 pKa = 3.06 NNPVFGAQSHH2367 pKa = 5.77 TPTIIEE2373 pKa = 4.33 SAPIGAFVFNVNATDD2388 pKa = 3.87 ADD2390 pKa = 4.06 SGGSGQVTYY2399 pKa = 11.29 SLIGGDD2405 pKa = 4.0 GKK2407 pKa = 9.91 FTINQDD2413 pKa = 3.11 TGVITLLQQVDD2424 pKa = 4.22 KK2425 pKa = 9.36 EE2426 pKa = 4.69 TQSQHH2431 pKa = 4.85 MLTVFARR2438 pKa = 11.84 DD2439 pKa = 3.57 NPGDD2443 pKa = 4.05 SEE2445 pKa = 4.41 DD2446 pKa = 3.92 SRR2448 pKa = 11.84 TGSTTVIVNVLDD2460 pKa = 4.35 ANEE2463 pKa = 4.23 FPPVVTQPIFTINEE2477 pKa = 3.87 GGIGGEE2483 pKa = 3.89 VVGIIEE2489 pKa = 5.56 AYY2491 pKa = 10.59 DD2492 pKa = 4.05 PDD2494 pKa = 6.17 DD2495 pKa = 5.41 PDD2497 pKa = 5.59 DD2498 pKa = 4.9 PNQSLYY2504 pKa = 10.59 YY2505 pKa = 10.16 VVVSSQPEE2513 pKa = 3.98 VGSTLFIINNVTGEE2527 pKa = 4.23 IITTGPLDD2535 pKa = 4.18 RR2536 pKa = 11.84 DD2537 pKa = 4.01 SGLHH2541 pKa = 5.88 PARR2544 pKa = 11.84 VDD2546 pKa = 3.48 LDD2548 pKa = 4.5 LIVYY2552 pKa = 10.51 DD2553 pKa = 5.29 DD2554 pKa = 4.57 GNPNLGTPTTAIIYY2568 pKa = 10.58 INDD2571 pKa = 3.86 LNDD2574 pKa = 3.24 NQPIFDD2580 pKa = 4.03 RR2581 pKa = 11.84 PLYY2584 pKa = 10.59 DD2585 pKa = 3.28 VTVVEE2590 pKa = 4.75 GQYY2593 pKa = 10.65 NDD2595 pKa = 4.66 PIITVVANDD2604 pKa = 3.93 PDD2606 pKa = 3.79 QNSNLRR2612 pKa = 11.84 YY2613 pKa = 9.87 KK2614 pKa = 10.52 ILGGNLNNTFVLVDD2628 pKa = 3.72 GGLIPVKK2635 pKa = 10.19 PLDD2638 pKa = 3.89 FEE2640 pKa = 4.7 TFTNYY2645 pKa = 10.82 NLTVVVTDD2653 pKa = 4.15 DD2654 pKa = 3.34 SGNRR2658 pKa = 11.84 DD2659 pKa = 3.26 TTYY2662 pKa = 11.16 VAVTVTDD2669 pKa = 4.48 ANDD2672 pKa = 3.62 HH2673 pKa = 6.31 NPTFVPDD2680 pKa = 4.56 LYY2682 pKa = 11.2 SLSVTEE2688 pKa = 4.7 NEE2690 pKa = 4.32 PPGTQVGVVMTIDD2703 pKa = 4.22 GDD2705 pKa = 4.1 TLPEE2709 pKa = 4.08 YY2710 pKa = 10.66 TDD2712 pKa = 3.65 IIYY2715 pKa = 9.01 TILTGNGLRR2724 pKa = 11.84 NFTINSTTGIINTATILDD2742 pKa = 3.83 RR2743 pKa = 11.84 EE2744 pKa = 4.39 KK2745 pKa = 10.06 TSEE2748 pKa = 4.08 YY2749 pKa = 10.62 VLTIGAEE2756 pKa = 4.11 NPVGGTTGTATVSIIVRR2773 pKa = 11.84 DD2774 pKa = 4.05 VNDD2777 pKa = 3.35 NTPTFEE2783 pKa = 4.33 EE2784 pKa = 4.1 NPYY2787 pKa = 10.08 TSTVTTNTLLVDD2799 pKa = 3.49 VHH2801 pKa = 8.14 ANDD2804 pKa = 4.41 PDD2806 pKa = 3.56 EE2807 pKa = 4.78 GGNGIVIYY2815 pKa = 9.83 EE2816 pKa = 4.0 IVSGNEE2822 pKa = 3.8 DD2823 pKa = 3.23 NRR2825 pKa = 11.84 FTIDD2829 pKa = 2.99 NRR2831 pKa = 11.84 TGVITLVNPLEE2842 pKa = 4.32 SQLIRR2847 pKa = 11.84 NYY2849 pKa = 8.04 TLVVIGHH2856 pKa = 6.93 DD2857 pKa = 3.48 LGNPRR2862 pKa = 11.84 LQSNTTVDD2870 pKa = 3.81 LRR2872 pKa = 11.84 INYY2875 pKa = 9.5 LGLNAPPSFVRR2886 pKa = 11.84 PNQGSTVFITEE2897 pKa = 4.01 NNPLGLLIINAFAVDD2912 pKa = 4.48 DD2913 pKa = 4.18 DD2914 pKa = 4.34 VGANGVVDD2922 pKa = 5.05 YY2923 pKa = 11.33 SILPNFDD2930 pKa = 3.62 YY2931 pKa = 11.32 SDD2933 pKa = 3.69 FTIDD2937 pKa = 4.36 PVTGDD2942 pKa = 2.97 ITILVSADD2950 pKa = 3.75 RR2951 pKa = 11.84 EE2952 pKa = 4.42 IKK2954 pKa = 10.37 DD2955 pKa = 3.68 SYY2957 pKa = 10.02 TLTVVATDD2965 pKa = 3.52 RR2966 pKa = 11.84 GDD2968 pKa = 3.97 PNLSTSSTFVIRR2980 pKa = 11.84 VLDD2983 pKa = 4.19 EE2984 pKa = 4.95 NDD2986 pKa = 4.14 DD2987 pKa = 3.78 NPAFPRR2993 pKa = 11.84 PDD2995 pKa = 3.11 GMNNPIVLNLNVFEE3009 pKa = 4.61 NANISDD3015 pKa = 4.02 LVGTVDD3021 pKa = 4.37 GAIDD3025 pKa = 4.57 LDD3027 pKa = 4.29 LGVNGQIFYY3036 pKa = 10.27 HH3037 pKa = 6.82 IVDD3040 pKa = 3.96 STVGGIFVINSTTGVVTVNGTLDD3063 pKa = 3.46 RR3064 pKa = 11.84 EE3065 pKa = 4.68 DD3066 pKa = 3.85 IGVHH3070 pKa = 5.75 TIYY3073 pKa = 10.64 ILATNDD3079 pKa = 2.65 ATYY3082 pKa = 11.35 NRR3084 pKa = 11.84 TGPYY3088 pKa = 10.05 NVLDD3092 pKa = 4.58 NISLKK3097 pKa = 8.86 EE3098 pKa = 4.02 VKK3100 pKa = 8.72 ITLLDD3105 pKa = 3.65 INDD3108 pKa = 3.91 NEE3110 pKa = 4.38 FTSTVKK3116 pKa = 10.28 SAYY3119 pKa = 10.35 ACMFDD3124 pKa = 4.97 NPCQNEE3130 pKa = 4.93 GICMEE3135 pKa = 5.34 DD3136 pKa = 3.4 EE3137 pKa = 4.82 DD3138 pKa = 5.13 NPGDD3142 pKa = 4.06 VKK3144 pKa = 10.97 CEE3146 pKa = 4.01 CPDD3149 pKa = 3.29 EE3150 pKa = 4.45 YY3151 pKa = 11.48 GGLYY3155 pKa = 10.38 CEE3157 pKa = 4.25 EE3158 pKa = 5.08 SIPNACMFDD3167 pKa = 3.65 NPCQNEE3173 pKa = 4.72 GTCMDD3178 pKa = 5.32 DD3179 pKa = 3.43 EE3180 pKa = 5.31 DD3181 pKa = 4.67 NPGNVKK3187 pKa = 9.8 CVCLDD3192 pKa = 3.78 GYY3194 pKa = 11.31 SGLDD3198 pKa = 3.47 CGEE3201 pKa = 3.65 ATPRR3205 pKa = 11.84 YY3206 pKa = 9.33 NLNILIAALAGLAVFMSLVSLIMICAKK3233 pKa = 10.15 ARR3235 pKa = 11.84 KK3236 pKa = 7.36 TSSARR3241 pKa = 11.84 NEE3243 pKa = 4.2 LNVSDD3248 pKa = 3.97 SCQRR3252 pKa = 11.84 PPQSVNNQPDD3262 pKa = 3.58 LEE3264 pKa = 4.5 AVANEE3269 pKa = 4.04 PNVPNGPMRR3278 pKa = 11.84 EE3279 pKa = 4.1 NTDD3282 pKa = 3.15 MANRR3286 pKa = 11.84 PLPSLPDD3293 pKa = 3.21 QPGAIVHH3300 pKa = 7.16 DD3301 pKa = 4.32 YY3302 pKa = 9.59 ATTLRR3307 pKa = 11.84 PLMRR3311 pKa = 11.84 QRR3313 pKa = 11.84 SNHH3316 pKa = 5.26 SFVV3319 pKa = 3.29
Molecular weight: 358.59 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 3.682
IPC2_protein 3.706
IPC_protein 3.77
Toseland 3.528
ProMoST 3.935
Dawson 3.77
Bjellqvist 3.923
Wikipedia 3.706
Rodwell 3.592
Grimsley 3.439
Solomon 3.77
Lehninger 3.732
Nozaki 3.872
DTASelect 4.151
Thurlkill 3.579
EMBOSS 3.719
Sillero 3.897
Patrickios 1.583
IPC_peptide 3.757
IPC2_peptide 3.872
IPC2.peptide.svr19 3.801
Protein with the highest isoelectric point:
>tr|A0A7M7RH65|A0A7M7RH65_STRPU Methyltransferase-like protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
MM1 pKa = 7.54 PASPQKK7 pKa = 10.26 RR8 pKa = 11.84 AASPRR13 pKa = 11.84 RR14 pKa = 11.84 SPKK17 pKa = 9.72 KK18 pKa = 10.34 SPRR21 pKa = 11.84 KK22 pKa = 9.49 SPKK25 pKa = 8.72 KK26 pKa = 9.86 SPRR29 pKa = 11.84 KK30 pKa = 9.3 RR31 pKa = 11.84 SASPRR36 pKa = 11.84 RR37 pKa = 11.84 RR38 pKa = 11.84 RR39 pKa = 11.84 RR40 pKa = 11.84 SNARR44 pKa = 11.84 AATHH48 pKa = 6.22 PPVLEE53 pKa = 4.44 MIRR56 pKa = 11.84 AAITAMKK63 pKa = 9.21 EE64 pKa = 3.82 RR65 pKa = 11.84 RR66 pKa = 11.84 GSSVSKK72 pKa = 9.47 IKK74 pKa = 10.74 SYY76 pKa = 10.5 IAANYY81 pKa = 8.17 RR82 pKa = 11.84 VNMANLQPHH91 pKa = 6.61 IRR93 pKa = 11.84 RR94 pKa = 11.84 ALRR97 pKa = 11.84 SGVTSGALKK106 pKa = 10.4 QVTGTGATGRR116 pKa = 11.84 FRR118 pKa = 11.84 VGVVPRR124 pKa = 11.84 PKK126 pKa = 10.21 KK127 pKa = 10.12 ARR129 pKa = 11.84 KK130 pKa = 7.4 TSAAAAAKK138 pKa = 9.47 KK139 pKa = 9.84 QRR141 pKa = 11.84 ARR143 pKa = 11.84 ARR145 pKa = 11.84 AVAKK149 pKa = 9.88 RR150 pKa = 11.84 AKK152 pKa = 9.91 AAARR156 pKa = 11.84 RR157 pKa = 11.84 KK158 pKa = 9.39 AAAAKK163 pKa = 10.09 KK164 pKa = 9.92 KK165 pKa = 9.38 ATAAKK170 pKa = 9.81 RR171 pKa = 11.84 KK172 pKa = 9.03 AARR175 pKa = 11.84 KK176 pKa = 7.8 AKK178 pKa = 9.93 KK179 pKa = 9.61 VRR181 pKa = 11.84 RR182 pKa = 11.84 PKK184 pKa = 10.07 KK185 pKa = 9.13 AAPKK189 pKa = 9.77 RR190 pKa = 11.84 RR191 pKa = 11.84 PAAKK195 pKa = 9.87 KK196 pKa = 9.48 AAKK199 pKa = 9.96 KK200 pKa = 8.61 STKK203 pKa = 9.93 KK204 pKa = 10.5 SPKK207 pKa = 8.6 KK208 pKa = 10.02 AKK210 pKa = 9.9 KK211 pKa = 9.18 AVKK214 pKa = 9.68 RR215 pKa = 11.84 RR216 pKa = 11.84 PAAKK220 pKa = 8.61 KK221 pKa = 7.75 TRR223 pKa = 11.84 RR224 pKa = 11.84 SPRR227 pKa = 11.84 KK228 pKa = 7.84 SAKK231 pKa = 9.48 ARR233 pKa = 11.84 RR234 pKa = 11.84 RR235 pKa = 11.84 SPRR238 pKa = 11.84 KK239 pKa = 9.3 AKK241 pKa = 10.29 KK242 pKa = 9.91
Molecular weight: 26.6 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 9.507
IPC2_protein 11.301
IPC_protein 12.735
Toseland 12.91
ProMoST 13.393
Dawson 12.91
Bjellqvist 12.896
Wikipedia 13.378
Rodwell 12.735
Grimsley 12.954
Solomon 13.393
Lehninger 13.305
Nozaki 12.91
DTASelect 12.896
Thurlkill 12.91
EMBOSS 13.408
Sillero 12.91
Patrickios 12.442
IPC_peptide 13.408
IPC2_peptide 12.384
IPC2.peptide.svr19 9.108
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
26461
7962
34423
23911872
33
24046
694.6
77.16
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
6.353 ± 0.012
2.317 ± 0.025
6.12 ± 0.012
6.685 ± 0.021
3.504 ± 0.01
6.631 ± 0.025
2.4 ± 0.01
4.976 ± 0.01
5.487 ± 0.023
8.151 ± 0.025
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.408 ± 0.008
4.472 ± 0.013
5.483 ± 0.017
4.429 ± 0.017
5.237 ± 0.016
8.595 ± 0.019
6.627 ± 0.041
6.305 ± 0.015
1.047 ± 0.005
2.77 ± 0.01
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here