Amino acid dipepetide frequency for Pararhizobium polonicum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.86AlaAla: 15.86 ± 0.118	0.945AlaCys: 0.945 ± 0.028	6.857AlaAsp: 6.857 ± 0.063	7.0AlaGlu: 7.0 ± 0.081	4.711AlaPhe: 4.711 ± 0.059	10.569AlaGly: 10.569 ± 0.081	2.072AlaHis: 2.072 ± 0.035	7.028AlaIle: 7.028 ± 0.072	4.409AlaLys: 4.409 ± 0.063	12.6AlaLeu: 12.6 ± 0.087	3.426AlaMet: 3.426 ± 0.049	3.078AlaAsn: 3.078 ± 0.043	4.525AlaPro: 4.525 ± 0.058	3.582AlaGln: 3.582 ± 0.047	7.453AlaArg: 7.453 ± 0.074	6.51AlaSer: 6.51 ± 0.062	5.916AlaThr: 5.916 ± 0.068	8.66AlaVal: 8.66 ± 0.078	1.32AlaTrp: 1.32 ± 0.03	2.577AlaTyr: 2.577 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.852CysAla: 0.852 ± 0.022	0.093CysCys: 0.093 ± 0.007	0.497CysAsp: 0.497 ± 0.014	0.402CysGlu: 0.402 ± 0.016	0.305CysPhe: 0.305 ± 0.013	0.901CysGly: 0.901 ± 0.026	0.211CysHis: 0.211 ± 0.012	0.423CysIle: 0.423 ± 0.015	0.194CysLys: 0.194 ± 0.011	0.799CysLeu: 0.799 ± 0.022	0.159CysMet: 0.159 ± 0.008	0.194CysAsn: 0.194 ± 0.009	0.359CysPro: 0.359 ± 0.014	0.217CysGln: 0.217 ± 0.01	0.51CysArg: 0.51 ± 0.017	0.427CysSer: 0.427 ± 0.013	0.393CysThr: 0.393 ± 0.017	0.583CysVal: 0.583 ± 0.019	0.103CysTrp: 0.103 ± 0.007	0.206CysTyr: 0.206 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.577AspAla: 6.577 ± 0.07	0.475AspCys: 0.475 ± 0.016	3.064AspAsp: 3.064 ± 0.051	3.279AspGlu: 3.279 ± 0.047	2.446AspPhe: 2.446 ± 0.039	5.188AspGly: 5.188 ± 0.056	1.281AspHis: 1.281 ± 0.027	3.66AspIle: 3.66 ± 0.046	1.901AspLys: 1.901 ± 0.036	5.764AspLeu: 5.764 ± 0.052	1.472AspMet: 1.472 ± 0.032	1.537AspAsn: 1.537 ± 0.028	3.228AspPro: 3.228 ± 0.047	1.636AspGln: 1.636 ± 0.031	4.01AspArg: 4.01 ± 0.047	2.168AspSer: 2.168 ± 0.041	2.814AspThr: 2.814 ± 0.049	4.199AspVal: 4.199 ± 0.052	0.929AspTrp: 0.929 ± 0.023	1.522AspTyr: 1.522 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	6.888GluAla: 6.888 ± 0.06	0.326GluCys: 0.326 ± 0.013	2.695GluAsp: 2.695 ± 0.038	3.138GluGlu: 3.138 ± 0.051	1.861GluPhe: 1.861 ± 0.032	4.031GluGly: 4.031 ± 0.047	1.123GluHis: 1.123 ± 0.023	3.783GluIle: 3.783 ± 0.049	2.688GluLys: 2.688 ± 0.046	4.999GluLeu: 4.999 ± 0.063	1.564GluMet: 1.564 ± 0.032	1.926GluAsn: 1.926 ± 0.038	2.579GluPro: 2.579 ± 0.04	2.025GluGln: 2.025 ± 0.034	4.291GluArg: 4.291 ± 0.053	2.34GluSer: 2.34 ± 0.041	3.897GluThr: 3.897 ± 0.055	3.362GluVal: 3.362 ± 0.044	0.66GluTrp: 0.66 ± 0.02	1.029GluTyr: 1.029 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.676PheAla: 4.676 ± 0.054	0.383PheCys: 0.383 ± 0.013	2.738PheAsp: 2.738 ± 0.041	2.258PheGlu: 2.258 ± 0.036	1.65PhePhe: 1.65 ± 0.037	3.935PheGly: 3.935 ± 0.048	0.768PheHis: 0.768 ± 0.02	2.081PheIle: 2.081 ± 0.038	1.231PheLys: 1.231 ± 0.026	3.712PheLeu: 3.712 ± 0.051	0.906PheMet: 0.906 ± 0.023	1.216PheAsn: 1.216 ± 0.027	1.68PhePro: 1.68 ± 0.028	1.143PheGln: 1.143 ± 0.026	2.238PheArg: 2.238 ± 0.034	2.686PheSer: 2.686 ± 0.041	2.044PheThr: 2.044 ± 0.033	2.961PheVal: 2.961 ± 0.045	0.573PheTrp: 0.573 ± 0.018	1.008PheTyr: 1.008 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	8.616GlyAla: 8.616 ± 0.079	0.787GlyCys: 0.787 ± 0.019	4.266GlyAsp: 4.266 ± 0.059	4.6GlyGlu: 4.6 ± 0.049	3.806GlyPhe: 3.806 ± 0.053	7.008GlyGly: 7.008 ± 0.083	1.842GlyHis: 1.842 ± 0.034	5.372GlyIle: 5.372 ± 0.057	3.906GlyLys: 3.906 ± 0.052	8.938GlyLeu: 8.938 ± 0.073	2.394GlyMet: 2.394 ± 0.038	2.501GlyAsn: 2.501 ± 0.052	3.159GlyPro: 3.159 ± 0.042	2.804GlyGln: 2.804 ± 0.04	5.548GlyArg: 5.548 ± 0.066	4.752GlySer: 4.752 ± 0.058	4.78GlyThr: 4.78 ± 0.065	5.861GlyVal: 5.861 ± 0.063	1.253GlyTrp: 1.253 ± 0.029	2.457GlyTyr: 2.457 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.242HisAla: 2.242 ± 0.037	0.217HisCys: 0.217 ± 0.011	1.249HisAsp: 1.249 ± 0.027	1.009HisGlu: 1.009 ± 0.025	0.915HisPhe: 0.915 ± 0.022	1.879HisGly: 1.879 ± 0.036	0.58HisHis: 0.58 ± 0.023	1.069HisIle: 1.069 ± 0.025	0.523HisLys: 0.523 ± 0.017	1.984HisLeu: 1.984 ± 0.032	0.532HisMet: 0.532 ± 0.019	0.477HisAsn: 0.477 ± 0.018	1.295HisPro: 1.295 ± 0.028	0.616HisGln: 0.616 ± 0.021	1.316HisArg: 1.316 ± 0.027	0.947HisSer: 0.947 ± 0.024	0.815HisThr: 0.815 ± 0.023	1.462HisVal: 1.462 ± 0.033	0.283HisTrp: 0.283 ± 0.013	0.537HisTyr: 0.537 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	8.124IleAla: 8.124 ± 0.073	0.556IleCys: 0.556 ± 0.018	4.062IleAsp: 4.062 ± 0.046	3.762IleGlu: 3.762 ± 0.053	2.051IlePhe: 2.051 ± 0.04	5.678IleGly: 5.678 ± 0.059	1.033IleHis: 1.033 ± 0.023	2.931IleIle: 2.931 ± 0.041	1.705IleLys: 1.705 ± 0.037	5.292IleLeu: 5.292 ± 0.06	1.182IleMet: 1.182 ± 0.029	1.671IleAsn: 1.671 ± 0.031	2.594IlePro: 2.594 ± 0.036	1.303IleGln: 1.303 ± 0.026	3.523IleArg: 3.523 ± 0.04	3.477IleSer: 3.477 ± 0.046	3.037IleThr: 3.037 ± 0.038	4.796IleVal: 4.796 ± 0.05	0.666IleTrp: 0.666 ± 0.02	1.318IleTyr: 1.318 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.871LysAla: 4.871 ± 0.06	0.146LysCys: 0.146 ± 0.009	2.052LysAsp: 2.052 ± 0.043	1.761LysGlu: 1.761 ± 0.04	1.02LysPhe: 1.02 ± 0.023	2.977LysGly: 2.977 ± 0.042	0.641LysHis: 0.641 ± 0.021	2.126LysIle: 2.126 ± 0.039	1.517LysLys: 1.517 ± 0.032	3.63LysLeu: 3.63 ± 0.052	0.93LysMet: 0.93 ± 0.028	1.071LysAsn: 1.071 ± 0.027	2.342LysPro: 2.342 ± 0.042	1.192LysGln: 1.192 ± 0.027	2.448LysArg: 2.448 ± 0.037	2.238LysSer: 2.238 ± 0.036	2.525LysThr: 2.525 ± 0.045	2.609LysVal: 2.609 ± 0.038	0.405LysTrp: 0.405 ± 0.015	0.703LysTyr: 0.703 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	12.507LeuAla: 12.507 ± 0.102	0.861LeuCys: 0.861 ± 0.021	5.878LeuAsp: 5.878 ± 0.066	5.23LeuGlu: 5.23 ± 0.056	3.916LeuPhe: 3.916 ± 0.057	8.077LeuGly: 8.077 ± 0.073	1.763LeuHis: 1.763 ± 0.032	5.519LeuIle: 5.519 ± 0.063	4.268LeuLys: 4.268 ± 0.054	9.376LeuLeu: 9.376 ± 0.094	2.45LeuMet: 2.45 ± 0.037	2.761LeuAsn: 2.761 ± 0.039	5.292LeuPro: 5.292 ± 0.062	2.896LeuGln: 2.896 ± 0.041	5.895LeuArg: 5.895 ± 0.071	7.279LeuSer: 7.279 ± 0.071	5.765LeuThr: 5.765 ± 0.053	7.26LeuVal: 7.26 ± 0.065	1.095LeuTrp: 1.095 ± 0.027	2.168LeuTyr: 2.168 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.125MetAla: 3.125 ± 0.042	0.145MetCys: 0.145 ± 0.009	1.2MetAsp: 1.2 ± 0.024	1.214MetGlu: 1.214 ± 0.023	0.764MetPhe: 0.764 ± 0.022	1.779MetGly: 1.779 ± 0.032	0.43MetHis: 0.43 ± 0.015	1.588MetIle: 1.588 ± 0.03	1.17MetLys: 1.17 ± 0.024	2.614MetLeu: 2.614 ± 0.045	0.737MetMet: 0.737 ± 0.019	0.868MetAsn: 0.868 ± 0.022	1.509MetPro: 1.509 ± 0.034	0.884MetGln: 0.884 ± 0.022	1.774MetArg: 1.774 ± 0.034	1.773MetSer: 1.773 ± 0.03	2.137MetThr: 2.137 ± 0.035	1.772MetVal: 1.772 ± 0.031	0.196MetTrp: 0.196 ± 0.009	0.333MetTyr: 0.333 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.343AsnAla: 3.343 ± 0.044	0.233AsnCys: 0.233 ± 0.014	1.591AsnAsp: 1.591 ± 0.042	1.354AsnGlu: 1.354 ± 0.027	1.093AsnPhe: 1.093 ± 0.03	2.751AsnGly: 2.751 ± 0.042	0.563AsnHis: 0.563 ± 0.017	1.668AsnIle: 1.668 ± 0.029	0.788AsnLys: 0.788 ± 0.023	2.819AsnLeu: 2.819 ± 0.041	0.721AsnMet: 0.721 ± 0.021	0.783AsnAsn: 0.783 ± 0.024	1.91AsnPro: 1.91 ± 0.033	0.822AsnGln: 0.822 ± 0.024	1.938AsnArg: 1.938 ± 0.034	1.426AsnSer: 1.426 ± 0.03	1.471AsnThr: 1.471 ± 0.033	2.084AsnVal: 2.084 ± 0.037	0.435AsnTrp: 0.435 ± 0.016	0.725AsnTyr: 0.725 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.648ProAla: 5.648 ± 0.064	0.272ProCys: 0.272 ± 0.013	3.458ProAsp: 3.458 ± 0.044	3.414ProGlu: 3.414 ± 0.049	2.056ProPhe: 2.056 ± 0.034	4.106ProGly: 4.106 ± 0.058	1.037ProHis: 1.037 ± 0.025	2.353ProIle: 2.353 ± 0.039	1.771ProLys: 1.771 ± 0.035	4.793ProLeu: 4.793 ± 0.058	1.168ProMet: 1.168 ± 0.022	1.302ProAsn: 1.302 ± 0.031	2.013ProPro: 2.013 ± 0.035	1.689ProGln: 1.689 ± 0.036	2.346ProArg: 2.346 ± 0.036	2.697ProSer: 2.697 ± 0.037	2.219ProThr: 2.219 ± 0.038	4.286ProVal: 4.286 ± 0.057	0.61ProTrp: 0.61 ± 0.019	1.219ProTyr: 1.219 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.92GlnAla: 3.92 ± 0.051	0.173GlnCys: 0.173 ± 0.011	1.501GlnAsp: 1.501 ± 0.035	1.489GlnGlu: 1.489 ± 0.027	1.117GlnPhe: 1.117 ± 0.024	2.206GlnGly: 2.206 ± 0.035	0.595GlnHis: 0.595 ± 0.018	1.966GlnIle: 1.966 ± 0.035	1.272GlnLys: 1.272 ± 0.029	2.907GlnLeu: 2.907 ± 0.044	0.956GlnMet: 0.956 ± 0.022	0.927GlnAsn: 0.927 ± 0.021	1.717GlnPro: 1.717 ± 0.032	1.309GlnGln: 1.309 ± 0.033	2.197GlnArg: 2.197 ± 0.04	1.949GlnSer: 1.949 ± 0.032	1.872GlnThr: 1.872 ± 0.037	2.025GlnVal: 2.025 ± 0.031	0.395GlnTrp: 0.395 ± 0.014	0.633GlnTyr: 0.633 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	6.586ArgAla: 6.586 ± 0.062	0.413ArgCys: 0.413 ± 0.016	3.86ArgAsp: 3.86 ± 0.047	3.6ArgGlu: 3.6 ± 0.048	2.809ArgPhe: 2.809 ± 0.04	4.211ArgGly: 4.211 ± 0.051	1.609ArgHis: 1.609 ± 0.025	4.096ArgIle: 4.096 ± 0.052	2.517ArgLys: 2.517 ± 0.043	6.899ArgLeu: 6.899 ± 0.083	1.837ArgMet: 1.837 ± 0.03	2.007ArgAsn: 2.007 ± 0.032	2.97ArgPro: 2.97 ± 0.042	2.538ArgGln: 2.538 ± 0.044	4.694ArgArg: 4.694 ± 0.066	3.555ArgSer: 3.555 ± 0.047	3.277ArgThr: 3.277 ± 0.042	4.13ArgVal: 4.13 ± 0.05	0.846ArgTrp: 0.846 ± 0.021	1.624ArgTyr: 1.624 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	6.391SerAla: 6.391 ± 0.067	0.398SerCys: 0.398 ± 0.015	3.139SerAsp: 3.139 ± 0.049	2.93SerGlu: 2.93 ± 0.045	2.549SerPhe: 2.549 ± 0.043	5.954SerGly: 5.954 ± 0.066	1.194SerHis: 1.194 ± 0.026	3.329SerIle: 3.329 ± 0.049	1.862SerLys: 1.862 ± 0.037	5.939SerLeu: 5.939 ± 0.071	1.462SerMet: 1.462 ± 0.031	1.56SerAsn: 1.56 ± 0.029	2.753SerPro: 2.753 ± 0.042	1.747SerGln: 1.747 ± 0.035	3.65SerArg: 3.65 ± 0.045	3.338SerSer: 3.338 ± 0.044	2.923SerThr: 2.923 ± 0.043	4.328SerVal: 4.328 ± 0.053	0.79SerTrp: 0.79 ± 0.021	1.393SerTyr: 1.393 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	6.59ThrAla: 6.59 ± 0.066	0.412ThrCys: 0.412 ± 0.015	2.994ThrAsp: 2.994 ± 0.041	2.746ThrGlu: 2.746 ± 0.04	2.242ThrPhe: 2.242 ± 0.038	5.326ThrGly: 5.326 ± 0.052	1.041ThrHis: 1.041 ± 0.026	3.486ThrIle: 3.486 ± 0.043	1.685ThrLys: 1.685 ± 0.035	5.935ThrLeu: 5.935 ± 0.063	1.339ThrMet: 1.339 ± 0.026	1.359ThrAsn: 1.359 ± 0.029	3.073ThrPro: 3.073 ± 0.042	1.467ThrGln: 1.467 ± 0.033	3.132ThrArg: 3.132 ± 0.043	3.035ThrSer: 3.035 ± 0.044	2.881ThrThr: 2.881 ± 0.047	4.765ThrVal: 4.765 ± 0.051	0.61ThrTrp: 0.61 ± 0.019	1.241ThrTyr: 1.241 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	8.608ValAla: 8.608 ± 0.082	0.616ValCys: 0.616 ± 0.019	3.89ValAsp: 3.89 ± 0.047	4.273ValGlu: 4.273 ± 0.048	3.023ValPhe: 3.023 ± 0.042	5.081ValGly: 5.081 ± 0.061	1.384ValHis: 1.384 ± 0.029	4.493ValIle: 4.493 ± 0.058	2.58ValLys: 2.58 ± 0.044	7.396ValLeu: 7.396 ± 0.067	1.95ValMet: 1.95 ± 0.03	2.132ValAsn: 2.132 ± 0.038	3.639ValPro: 3.639 ± 0.041	1.932ValGln: 1.932 ± 0.039	4.468ValArg: 4.468 ± 0.054	4.929ValSer: 4.929 ± 0.057	4.727ValThr: 4.727 ± 0.046	5.572ValVal: 5.572 ± 0.07	0.844ValTrp: 0.844 ± 0.024	1.555ValTyr: 1.555 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.162TrpAla: 1.162 ± 0.026	0.129TrpCys: 0.129 ± 0.01	0.628TrpAsp: 0.628 ± 0.021	0.53TrpGlu: 0.53 ± 0.018	0.536TrpPhe: 0.536 ± 0.02	0.821TrpGly: 0.821 ± 0.023	0.302TrpHis: 0.302 ± 0.014	0.668TrpIle: 0.668 ± 0.021	0.501TrpLys: 0.501 ± 0.018	1.535TrpLeu: 1.535 ± 0.031	0.34TrpMet: 0.34 ± 0.014	0.485TrpAsn: 0.485 ± 0.014	0.65TrpPro: 0.65 ± 0.018	0.572TrpGln: 0.572 ± 0.018	0.895TrpArg: 0.895 ± 0.023	0.831TrpSer: 0.831 ± 0.022	0.706TrpThr: 0.706 ± 0.021	0.743TrpVal: 0.743 ± 0.02	0.211TrpTrp: 0.211 ± 0.012	0.305TrpTyr: 0.305 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.513TyrAla: 2.513 ± 0.039	0.248TyrCys: 0.248 ± 0.012	1.528TyrAsp: 1.528 ± 0.03	1.217TyrGlu: 1.217 ± 0.027	1.017TyrPhe: 1.017 ± 0.025	2.172TyrGly: 2.172 ± 0.036	0.479TyrHis: 0.479 ± 0.015	1.124TyrIle: 1.124 ± 0.025	0.716TyrLys: 0.716 ± 0.021	2.324TyrLeu: 2.324 ± 0.038	0.49TyrMet: 0.49 ± 0.018	0.66TyrAsn: 0.66 ± 0.019	1.171TyrPro: 1.171 ± 0.026	0.752TyrGln: 0.752 ± 0.02	1.75TyrArg: 1.75 ± 0.03	1.271TyrSer: 1.271 ± 0.028	1.16TyrThr: 1.16 ± 0.023	1.634TyrVal: 1.634 ± 0.03	0.327TyrTrp: 0.327 ± 0.014	0.637TyrTyr: 0.637 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5658 proteins (1784372 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---