Amino acid dipepetide frequency for Soonwooa buanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.285AlaAla: 4.285 ± 0.085	0.55AlaCys: 0.55 ± 0.024	3.535AlaAsp: 3.535 ± 0.059	4.178AlaGlu: 4.178 ± 0.073	3.379AlaPhe: 3.379 ± 0.056	4.335AlaGly: 4.335 ± 0.077	1.004AlaHis: 1.004 ± 0.031	4.939AlaIle: 4.939 ± 0.074	5.384AlaLys: 5.384 ± 0.086	5.981AlaLeu: 5.981 ± 0.09	1.693AlaMet: 1.693 ± 0.045	3.843AlaAsn: 3.843 ± 0.073	1.795AlaPro: 1.795 ± 0.045	2.62AlaGln: 2.62 ± 0.064	1.805AlaArg: 1.805 ± 0.042	4.156AlaSer: 4.156 ± 0.073	3.74AlaThr: 3.74 ± 0.084	4.069AlaVal: 4.069 ± 0.076	0.601AlaTrp: 0.601 ± 0.022	2.486AlaTyr: 2.486 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.423CysAla: 0.423 ± 0.023	0.092CysCys: 0.092 ± 0.01	0.363CysAsp: 0.363 ± 0.019	0.427CysGlu: 0.427 ± 0.023	0.418CysPhe: 0.418 ± 0.018	0.611CysGly: 0.611 ± 0.025	0.165CysHis: 0.165 ± 0.016	0.602CysIle: 0.602 ± 0.023	0.493CysLys: 0.493 ± 0.023	0.601CysLeu: 0.601 ± 0.025	0.142CysMet: 0.142 ± 0.012	0.342CysAsn: 0.342 ± 0.019	0.3CysPro: 0.3 ± 0.021	0.215CysGln: 0.215 ± 0.014	0.196CysArg: 0.196 ± 0.013	0.539CysSer: 0.539 ± 0.026	0.352CysThr: 0.352 ± 0.02	0.428CysVal: 0.428 ± 0.023	0.049CysTrp: 0.049 ± 0.007	0.3CysTyr: 0.3 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.732AspAla: 3.732 ± 0.064	0.394AspCys: 0.394 ± 0.022	2.976AspAsp: 2.976 ± 0.063	3.876AspGlu: 3.876 ± 0.076	4.067AspPhe: 4.067 ± 0.065	3.478AspGly: 3.478 ± 0.075	0.848AspHis: 0.848 ± 0.032	4.296AspIle: 4.296 ± 0.084	4.612AspLys: 4.612 ± 0.078	5.379AspLeu: 5.379 ± 0.081	1.194AspMet: 1.194 ± 0.035	3.384AspAsn: 3.384 ± 0.076	1.651AspPro: 1.651 ± 0.046	1.821AspGln: 1.821 ± 0.045	1.738AspArg: 1.738 ± 0.041	3.117AspSer: 3.117 ± 0.058	2.289AspThr: 2.289 ± 0.057	3.715AspVal: 3.715 ± 0.069	0.764AspTrp: 0.764 ± 0.024	2.92AspTyr: 2.92 ± 0.064	0.0AspXaa: 0.0 ± 0.0
Glu	4.329GluAla: 4.329 ± 0.089	0.304GluCys: 0.304 ± 0.017	3.485GluAsp: 3.485 ± 0.07	4.641GluGlu: 4.641 ± 0.103	3.088GluPhe: 3.088 ± 0.056	3.121GluGly: 3.121 ± 0.061	1.054GluHis: 1.054 ± 0.031	5.673GluIle: 5.673 ± 0.091	6.632GluLys: 6.632 ± 0.093	5.73GluLeu: 5.73 ± 0.095	1.638GluMet: 1.638 ± 0.042	5.038GluAsn: 5.038 ± 0.083	1.402GluPro: 1.402 ± 0.04	2.283GluGln: 2.283 ± 0.054	2.22GluArg: 2.22 ± 0.05	3.32GluSer: 3.32 ± 0.061	3.23GluThr: 3.23 ± 0.064	4.271GluVal: 4.271 ± 0.073	0.58GluTrp: 0.58 ± 0.028	2.324GluTyr: 2.324 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	3.585PheAla: 3.585 ± 0.065	0.502PheCys: 0.502 ± 0.022	3.35PheAsp: 3.35 ± 0.062	3.45PheGlu: 3.45 ± 0.061	2.943PhePhe: 2.943 ± 0.067	3.832PheGly: 3.832 ± 0.067	0.839PheHis: 0.839 ± 0.023	3.776PheIle: 3.776 ± 0.072	3.707PheLys: 3.707 ± 0.068	5.093PheLeu: 5.093 ± 0.094	1.146PheMet: 1.146 ± 0.036	3.317PheAsn: 3.317 ± 0.061	1.864PhePro: 1.864 ± 0.039	1.671PheGln: 1.671 ± 0.041	1.735PheArg: 1.735 ± 0.044	4.205PheSer: 4.205 ± 0.08	2.749PheThr: 2.749 ± 0.051	3.48PheVal: 3.48 ± 0.066	0.644PheTrp: 0.644 ± 0.027	2.401PheTyr: 2.401 ± 0.061	0.0PheXaa: 0.0 ± 0.0
Gly	3.951GlyAla: 3.951 ± 0.079	0.499GlyCys: 0.499 ± 0.025	3.148GlyAsp: 3.148 ± 0.057	3.404GlyGlu: 3.404 ± 0.064	3.602GlyPhe: 3.602 ± 0.066	4.385GlyGly: 4.385 ± 0.092	0.981GlyHis: 0.981 ± 0.028	5.043GlyIle: 5.043 ± 0.08	5.29GlyLys: 5.29 ± 0.083	5.349GlyLeu: 5.349 ± 0.08	1.532GlyMet: 1.532 ± 0.04	3.627GlyAsn: 3.627 ± 0.07	1.186GlyPro: 1.186 ± 0.036	2.062GlyGln: 2.062 ± 0.041	1.968GlyArg: 1.968 ± 0.049	3.929GlySer: 3.929 ± 0.073	3.708GlyThr: 3.708 ± 0.081	4.174GlyVal: 4.174 ± 0.081	0.699GlyTrp: 0.699 ± 0.025	2.602GlyTyr: 2.602 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	0.876HisAla: 0.876 ± 0.034	0.154HisCys: 0.154 ± 0.013	0.804HisAsp: 0.804 ± 0.031	0.896HisGlu: 0.896 ± 0.03	1.107HisPhe: 1.107 ± 0.037	0.889HisGly: 0.889 ± 0.031	0.436HisHis: 0.436 ± 0.022	1.175HisIle: 1.175 ± 0.033	1.083HisLys: 1.083 ± 0.031	1.569HisLeu: 1.569 ± 0.046	0.31HisMet: 0.31 ± 0.02	0.895HisAsn: 0.895 ± 0.031	0.81HisPro: 0.81 ± 0.029	0.752HisGln: 0.752 ± 0.028	0.618HisArg: 0.618 ± 0.028	1.02HisSer: 1.02 ± 0.036	0.784HisThr: 0.784 ± 0.027	0.753HisVal: 0.753 ± 0.032	0.226HisTrp: 0.226 ± 0.015	0.812HisTyr: 0.812 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	5.283IleAla: 5.283 ± 0.083	0.624IleCys: 0.624 ± 0.025	4.676IleAsp: 4.676 ± 0.073	5.003IleGlu: 5.003 ± 0.08	4.059IlePhe: 4.059 ± 0.073	4.891IleGly: 4.891 ± 0.079	1.189IleHis: 1.189 ± 0.037	6.042IleIle: 6.042 ± 0.098	6.227IleLys: 6.227 ± 0.088	7.44IleLeu: 7.44 ± 0.106	1.477IleMet: 1.477 ± 0.035	4.932IleAsn: 4.932 ± 0.063	3.171IlePro: 3.171 ± 0.062	2.622IleGln: 2.622 ± 0.053	2.295IleArg: 2.295 ± 0.053	5.992IleSer: 5.992 ± 0.077	4.134IleThr: 4.134 ± 0.073	4.593IleVal: 4.593 ± 0.086	0.7IleTrp: 0.7 ± 0.028	2.966IleTyr: 2.966 ± 0.058	0.0IleXaa: 0.0 ± 0.0
Lys	5.348LysAla: 5.348 ± 0.087	0.341LysCys: 0.341 ± 0.019	5.197LysAsp: 5.197 ± 0.093	5.932LysGlu: 5.932 ± 0.095	3.617LysPhe: 3.617 ± 0.067	4.221LysGly: 4.221 ± 0.069	1.333LysHis: 1.333 ± 0.039	7.289LysIle: 7.289 ± 0.088	7.522LysLys: 7.522 ± 0.102	7.211LysLeu: 7.211 ± 0.081	2.44LysMet: 2.44 ± 0.052	6.402LysAsn: 6.402 ± 0.098	2.576LysPro: 2.576 ± 0.057	2.873LysGln: 2.873 ± 0.056	2.505LysArg: 2.505 ± 0.049	5.382LysSer: 5.382 ± 0.091	5.163LysThr: 5.163 ± 0.075	5.077LysVal: 5.077 ± 0.076	0.739LysTrp: 0.739 ± 0.029	3.296LysTyr: 3.296 ± 0.067	0.0LysXaa: 0.0 ± 0.0
Leu	5.977LeuAla: 5.977 ± 0.088	0.664LeuCys: 0.664 ± 0.026	5.065LeuAsp: 5.065 ± 0.069	5.918LeuGlu: 5.918 ± 0.086	4.642LeuPhe: 4.642 ± 0.089	5.891LeuGly: 5.891 ± 0.087	1.431LeuHis: 1.431 ± 0.043	6.761LeuIle: 6.761 ± 0.119	8.337LeuLys: 8.337 ± 0.108	8.138LeuLeu: 8.138 ± 0.113	2.232LeuMet: 2.232 ± 0.052	5.644LeuAsn: 5.644 ± 0.073	3.348LeuPro: 3.348 ± 0.052	3.398LeuGln: 3.398 ± 0.059	2.948LeuArg: 2.948 ± 0.058	6.784LeuSer: 6.784 ± 0.091	4.84LeuThr: 4.84 ± 0.077	5.476LeuVal: 5.476 ± 0.084	0.778LeuTrp: 0.778 ± 0.028	3.178LeuTyr: 3.178 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	1.628MetAla: 1.628 ± 0.048	0.139MetCys: 0.139 ± 0.01	1.243MetAsp: 1.243 ± 0.035	1.389MetGlu: 1.389 ± 0.04	1.007MetPhe: 1.007 ± 0.038	1.41MetGly: 1.41 ± 0.039	0.373MetHis: 0.373 ± 0.018	1.736MetIle: 1.736 ± 0.046	2.577MetLys: 2.577 ± 0.053	2.245MetLeu: 2.245 ± 0.048	0.766MetMet: 0.766 ± 0.033	1.364MetAsn: 1.364 ± 0.036	0.945MetPro: 0.945 ± 0.032	0.874MetGln: 0.874 ± 0.028	0.829MetArg: 0.829 ± 0.029	1.594MetSer: 1.594 ± 0.038	1.305MetThr: 1.305 ± 0.041	1.247MetVal: 1.247 ± 0.033	0.177MetTrp: 0.177 ± 0.013	0.728MetTyr: 0.728 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	4.052AsnAla: 4.052 ± 0.071	0.437AsnCys: 0.437 ± 0.024	3.396AsnAsp: 3.396 ± 0.059	3.528AsnGlu: 3.528 ± 0.048	3.845AsnPhe: 3.845 ± 0.065	3.843AsnGly: 3.843 ± 0.067	1.045AsnHis: 1.045 ± 0.031	5.424AsnIle: 5.424 ± 0.074	4.576AsnLys: 4.576 ± 0.073	6.393AsnLeu: 6.393 ± 0.094	1.333AsnMet: 1.333 ± 0.038	4.162AsnAsn: 4.162 ± 0.093	2.981AsnPro: 2.981 ± 0.055	2.658AsnGln: 2.658 ± 0.05	1.996AsnArg: 1.996 ± 0.044	3.979AsnSer: 3.979 ± 0.086	3.353AsnThr: 3.353 ± 0.071	3.879AsnVal: 3.879 ± 0.066	0.815AsnTrp: 0.815 ± 0.032	3.16AsnTyr: 3.16 ± 0.068	0.0AsnXaa: 0.0 ± 0.0
Pro	2.029ProAla: 2.029 ± 0.05	0.199ProCys: 0.199 ± 0.013	1.968ProAsp: 1.968 ± 0.044	2.815ProGlu: 2.815 ± 0.058	1.73ProPhe: 1.73 ± 0.041	1.57ProGly: 1.57 ± 0.042	0.52ProHis: 0.52 ± 0.024	2.66ProIle: 2.66 ± 0.058	2.864ProLys: 2.864 ± 0.055	2.599ProLeu: 2.599 ± 0.051	0.813ProMet: 0.813 ± 0.03	2.497ProAsn: 2.497 ± 0.052	0.742ProPro: 0.742 ± 0.034	1.225ProGln: 1.225 ± 0.034	0.897ProArg: 0.897 ± 0.031	2.084ProSer: 2.084 ± 0.048	2.108ProThr: 2.108 ± 0.051	2.148ProVal: 2.148 ± 0.054	0.299ProTrp: 0.299 ± 0.018	1.362ProTyr: 1.362 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	2.144GlnAla: 2.144 ± 0.051	0.159GlnCys: 0.159 ± 0.013	1.881GlnAsp: 1.881 ± 0.042	2.259GlnGlu: 2.259 ± 0.051	1.793GlnPhe: 1.793 ± 0.04	1.706GlnGly: 1.706 ± 0.043	0.62GlnHis: 0.62 ± 0.028	2.888GlnIle: 2.888 ± 0.063	3.57GlnLys: 3.57 ± 0.073	3.48GlnLeu: 3.48 ± 0.065	0.945GlnMet: 0.945 ± 0.033	2.891GlnAsn: 2.891 ± 0.06	1.053GlnPro: 1.053 ± 0.03	1.657GlnGln: 1.657 ± 0.043	1.26GlnArg: 1.26 ± 0.038	2.176GlnSer: 2.176 ± 0.054	1.969GlnThr: 1.969 ± 0.049	2.016GlnVal: 2.016 ± 0.048	0.351GlnTrp: 0.351 ± 0.02	1.595GlnTyr: 1.595 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	1.836ArgAla: 1.836 ± 0.049	0.184ArgCys: 0.184 ± 0.013	1.661ArgAsp: 1.661 ± 0.039	2.047ArgGlu: 2.047 ± 0.052	1.758ArgPhe: 1.758 ± 0.041	1.655ArgGly: 1.655 ± 0.043	0.54ArgHis: 0.54 ± 0.024	2.748ArgIle: 2.748 ± 0.051	2.793ArgLys: 2.793 ± 0.057	2.911ArgLeu: 2.911 ± 0.056	0.882ArgMet: 0.882 ± 0.03	2.167ArgAsn: 2.167 ± 0.049	1.01ArgPro: 1.01 ± 0.035	1.166ArgGln: 1.166 ± 0.039	1.138ArgArg: 1.138 ± 0.034	1.753ArgSer: 1.753 ± 0.045	1.552ArgThr: 1.552 ± 0.036	1.827ArgVal: 1.827 ± 0.045	0.299ArgTrp: 0.299 ± 0.019	1.331ArgTyr: 1.331 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.091SerAla: 4.091 ± 0.073	0.579SerCys: 0.579 ± 0.027	3.576SerAsp: 3.576 ± 0.066	4.177SerGlu: 4.177 ± 0.072	3.996SerPhe: 3.996 ± 0.072	4.512SerGly: 4.512 ± 0.078	1.022SerHis: 1.022 ± 0.033	5.264SerIle: 5.264 ± 0.084	5.416SerLys: 5.416 ± 0.082	6.132SerLeu: 6.132 ± 0.096	1.377SerMet: 1.377 ± 0.04	3.907SerAsn: 3.907 ± 0.079	2.18SerPro: 2.18 ± 0.048	2.478SerGln: 2.478 ± 0.049	1.92SerArg: 1.92 ± 0.046	4.307SerSer: 4.307 ± 0.092	3.629SerThr: 3.629 ± 0.068	3.991SerVal: 3.991 ± 0.052	0.678SerTrp: 0.678 ± 0.029	2.688SerTyr: 2.688 ± 0.06	0.0SerXaa: 0.0 ± 0.0
Thr	3.616ThrAla: 3.616 ± 0.068	0.339ThrCys: 0.339 ± 0.019	3.13ThrAsp: 3.13 ± 0.06	3.527ThrGlu: 3.527 ± 0.065	2.68ThrPhe: 2.68 ± 0.061	3.65ThrGly: 3.65 ± 0.078	0.83ThrHis: 0.83 ± 0.03	4.063ThrIle: 4.063 ± 0.067	4.372ThrLys: 4.372 ± 0.069	4.755ThrLeu: 4.755 ± 0.069	1.072ThrMet: 1.072 ± 0.027	3.257ThrAsn: 3.257 ± 0.074	2.342ThrPro: 2.342 ± 0.051	1.924ThrGln: 1.924 ± 0.047	1.486ThrArg: 1.486 ± 0.037	3.869ThrSer: 3.869 ± 0.074	3.567ThrThr: 3.567 ± 0.078	3.166ThrVal: 3.166 ± 0.073	0.603ThrTrp: 0.603 ± 0.025	2.297ThrTyr: 2.297 ± 0.055	0.0ThrXaa: 0.0 ± 0.0
Val	4.205ValAla: 4.205 ± 0.071	0.471ValCys: 0.471 ± 0.023	3.641ValAsp: 3.641 ± 0.072	3.929ValGlu: 3.929 ± 0.069	3.307ValPhe: 3.307 ± 0.063	4.015ValGly: 4.015 ± 0.073	0.834ValHis: 0.834 ± 0.034	4.436ValIle: 4.436 ± 0.078	4.941ValLys: 4.941 ± 0.068	5.656ValLeu: 5.656 ± 0.074	1.491ValMet: 1.491 ± 0.038	3.709ValAsn: 3.709 ± 0.07	2.065ValPro: 2.065 ± 0.052	1.779ValGln: 1.779 ± 0.046	1.846ValArg: 1.846 ± 0.044	4.341ValSer: 4.341 ± 0.068	3.318ValThr: 3.318 ± 0.059	4.074ValVal: 4.074 ± 0.083	0.575ValTrp: 0.575 ± 0.023	2.451ValTyr: 2.451 ± 0.058	0.0ValXaa: 0.0 ± 0.0
Trp	0.603TrpAla: 0.603 ± 0.027	0.084TrpCys: 0.084 ± 0.01	0.611TrpAsp: 0.611 ± 0.028	0.655TrpGlu: 0.655 ± 0.028	0.54TrpPhe: 0.54 ± 0.023	0.616TrpGly: 0.616 ± 0.032	0.177TrpHis: 0.177 ± 0.013	0.783TrpIle: 0.783 ± 0.028	0.904TrpLys: 0.904 ± 0.03	0.919TrpLeu: 0.919 ± 0.033	0.319TrpMet: 0.319 ± 0.021	0.724TrpAsn: 0.724 ± 0.028	0.195TrpPro: 0.195 ± 0.017	0.427TrpGln: 0.427 ± 0.021	0.33TrpArg: 0.33 ± 0.02	0.636TrpSer: 0.636 ± 0.024	0.614TrpThr: 0.614 ± 0.029	0.564TrpVal: 0.564 ± 0.023	0.126TrpTrp: 0.126 ± 0.012	0.401TrpTyr: 0.401 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.385TyrAla: 2.385 ± 0.048	0.344TyrCys: 0.344 ± 0.021	2.547TyrAsp: 2.547 ± 0.054	2.311TyrGlu: 2.311 ± 0.051	2.711TyrPhe: 2.711 ± 0.059	2.508TyrGly: 2.508 ± 0.054	0.727TyrHis: 0.727 ± 0.028	2.721TyrIle: 2.721 ± 0.058	3.164TyrLys: 3.164 ± 0.063	3.866TyrLeu: 3.866 ± 0.075	0.773TyrMet: 0.773 ± 0.029	2.754TyrAsn: 2.754 ± 0.068	1.513TyrPro: 1.513 ± 0.037	1.91TyrGln: 1.91 ± 0.052	1.529TyrArg: 1.529 ± 0.041	2.736TyrSer: 2.736 ± 0.059	2.138TyrThr: 2.138 ± 0.053	2.134TyrVal: 2.134 ± 0.051	0.526TyrTrp: 0.526 ± 0.024	2.009TyrTyr: 2.009 ± 0.061	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3053 proteins (992948 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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