Amino acid dipepetide frequency for Grapevine virus G

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.241AlaAla: 3.241 ± 2.308
1.621AlaCys: 1.621 ± 0.822
3.241AlaAsp: 3.241 ± 1.089
3.241AlaGlu: 3.241 ± 0.549
2.836AlaPhe: 2.836 ± 0.865
3.241AlaGly: 3.241 ± 1.136
2.431AlaHis: 2.431 ± 1.234
2.836AlaIle: 2.836 ± 2.181
6.888AlaLys: 6.888 ± 2.415
7.699AlaLeu: 7.699 ± 2.038
0.81AlaMet: 0.81 ± 0.411
2.836AlaAsn: 2.836 ± 1.113
1.621AlaPro: 1.621 ± 0.822
2.431AlaGln: 2.431 ± 2.179
1.621AlaArg: 1.621 ± 0.822
6.888AlaSer: 6.888 ± 1.956
2.836AlaThr: 2.836 ± 0.821
2.431AlaVal: 2.431 ± 0.431
0.405AlaTrp: 0.405 ± 0.206
2.836AlaTyr: 2.836 ± 0.684
0.0AlaXaa: 0.0 ± 0.0
Cys
1.621CysAla: 1.621 ± 0.806
0.81CysCys: 0.81 ± 0.411
0.405CysAsp: 0.405 ± 0.206
1.216CysGlu: 1.216 ± 1.534
1.216CysPhe: 1.216 ± 0.617
2.836CysGly: 2.836 ± 0.918
0.405CysHis: 0.405 ± 0.206
0.81CysIle: 0.81 ± 0.411
1.621CysLys: 1.621 ± 1.482
2.836CysLeu: 2.836 ± 0.808
0.0CysMet: 0.0 ± 0.0
1.216CysAsn: 1.216 ± 0.617
0.81CysPro: 0.81 ± 0.695
0.0CysGln: 0.0 ± 0.0
1.216CysArg: 1.216 ± 0.49
0.405CysSer: 0.405 ± 0.206
0.405CysThr: 0.405 ± 0.206
1.216CysVal: 1.216 ± 0.951
0.0CysTrp: 0.0 ± 0.0
1.621CysTyr: 1.621 ± 1.812
0.0CysXaa: 0.0 ± 0.0
Asp
4.052AspAla: 4.052 ± 0.994
0.0AspCys: 0.0 ± 0.0
3.241AspAsp: 3.241 ± 0.708
5.267AspGlu: 5.267 ± 1.071
4.052AspPhe: 4.052 ± 2.143
6.078AspGly: 6.078 ± 2.188
1.621AspHis: 1.621 ± 0.822
2.026AspIle: 2.026 ± 1.035
2.431AspLys: 2.431 ± 1.563
7.293AspLeu: 7.293 ± 1.052
1.216AspMet: 1.216 ± 0.617
0.81AspAsn: 0.81 ± 0.411
4.052AspPro: 4.052 ± 1.314
1.216AspGln: 1.216 ± 0.617
2.836AspArg: 2.836 ± 0.723
2.431AspSer: 2.431 ± 0.857
1.621AspThr: 1.621 ± 1.042
2.836AspVal: 2.836 ± 1.505
1.216AspTrp: 1.216 ± 0.539
2.431AspTyr: 2.431 ± 1.234
0.0AspXaa: 0.0 ± 0.0
Glu
5.673GluAla: 5.673 ± 1.696
0.81GluCys: 0.81 ± 0.411
4.457GluAsp: 4.457 ± 1.053
5.673GluGlu: 5.673 ± 0.935
3.647GluPhe: 3.647 ± 1.851
5.673GluGly: 5.673 ± 1.192
1.621GluHis: 1.621 ± 0.822
4.862GluIle: 4.862 ± 2.055
5.673GluLys: 5.673 ± 0.987
6.078GluLeu: 6.078 ± 1.674
1.621GluMet: 1.621 ± 0.822
2.026GluAsn: 2.026 ± 0.638
2.431GluPro: 2.431 ± 1.894
2.026GluGln: 2.026 ± 1.028
3.647GluArg: 3.647 ± 1.353
5.267GluSer: 5.267 ± 1.479
4.457GluThr: 4.457 ± 1.039
4.052GluVal: 4.052 ± 0.869
0.405GluTrp: 0.405 ± 0.206
2.431GluTyr: 2.431 ± 1.234
0.0GluXaa: 0.0 ± 0.0
Phe
3.647PheAla: 3.647 ± 1.27
1.621PheCys: 1.621 ± 1.042
3.241PheAsp: 3.241 ± 0.683
3.241PheGlu: 3.241 ± 0.549
2.431PhePhe: 2.431 ± 1.234
2.836PheGly: 2.836 ± 0.857
0.405PheHis: 0.405 ± 0.206
2.836PheIle: 2.836 ± 1.439
3.241PheLys: 3.241 ± 1.084
6.078PheLeu: 6.078 ± 2.171
2.836PheMet: 2.836 ± 2.675
0.81PheAsn: 0.81 ± 0.411
1.621PhePro: 1.621 ± 0.806
0.405PheGln: 0.405 ± 0.206
3.241PheArg: 3.241 ± 0.769
4.457PheSer: 4.457 ± 2.795
3.647PheThr: 3.647 ± 1.353
1.621PheVal: 1.621 ± 0.822
0.0PheTrp: 0.0 ± 0.0
0.405PheTyr: 0.405 ± 0.206
0.0PheXaa: 0.0 ± 0.0
Gly
3.647GlyAla: 3.647 ± 0.876
1.216GlyCys: 1.216 ± 0.951
3.241GlyAsp: 3.241 ± 0.708
6.078GlyGlu: 6.078 ± 1.466
3.241GlyPhe: 3.241 ± 0.9
3.647GlyGly: 3.647 ± 0.838
0.81GlyHis: 0.81 ± 0.411
4.862GlyIle: 4.862 ± 1.107
2.026GlyLys: 2.026 ± 0.657
7.699GlyLeu: 7.699 ± 1.433
0.81GlyMet: 0.81 ± 0.393
2.836GlyAsn: 2.836 ± 2.239
4.052GlyPro: 4.052 ± 0.863
2.026GlyGln: 2.026 ± 1.201
2.026GlyArg: 2.026 ± 0.505
4.457GlySer: 4.457 ± 2.594
4.862GlyThr: 4.862 ± 1.193
4.457GlyVal: 4.457 ± 2.141
0.81GlyTrp: 0.81 ± 0.411
3.241GlyTyr: 3.241 ± 1.036
0.0GlyXaa: 0.0 ± 0.0
His
2.026HisAla: 2.026 ± 0.738
0.405HisCys: 0.405 ± 0.206
1.621HisAsp: 1.621 ± 0.822
0.405HisGlu: 0.405 ± 0.206
1.621HisPhe: 1.621 ± 0.542
0.81HisGly: 0.81 ± 0.521
1.216HisHis: 1.216 ± 0.648
4.052HisIle: 4.052 ± 1.529
0.81HisLys: 0.81 ± 0.623
2.836HisLeu: 2.836 ± 1.005
1.621HisMet: 1.621 ± 0.822
1.216HisAsn: 1.216 ± 0.564
2.026HisPro: 2.026 ± 0.505
0.81HisGln: 0.81 ± 0.631
1.216HisArg: 1.216 ± 1.479
2.431HisSer: 2.431 ± 0.857
0.0HisThr: 0.0 ± 0.0
1.216HisVal: 1.216 ± 0.617
0.0HisTrp: 0.0 ± 0.0
1.216HisTyr: 1.216 ± 0.564
0.0HisXaa: 0.0 ± 0.0
Ile
2.026IleAla: 2.026 ± 0.738
1.216IleCys: 1.216 ± 0.49
4.052IleAsp: 4.052 ± 1.981
4.052IleGlu: 4.052 ± 1.406
2.836IlePhe: 2.836 ± 0.449
5.267IleGly: 5.267 ± 0.922
1.621IleHis: 1.621 ± 0.663
4.457IleIle: 4.457 ± 0.523
6.078IleLys: 6.078 ± 0.89
5.267IleLeu: 5.267 ± 1.089
1.216IleMet: 1.216 ± 0.49
1.621IleAsn: 1.621 ± 0.937
2.431IlePro: 2.431 ± 0.857
0.405IleGln: 0.405 ± 0.206
4.052IleArg: 4.052 ± 1.611
6.888IleSer: 6.888 ± 1.224
1.216IleThr: 1.216 ± 0.539
2.836IleVal: 2.836 ± 0.449
0.405IleTrp: 0.405 ± 0.206
2.431IleTyr: 2.431 ± 0.595
0.0IleXaa: 0.0 ± 0.0
Lys
5.267LysAla: 5.267 ± 1.313
2.836LysCys: 2.836 ± 1.222
4.052LysAsp: 4.052 ± 0.901
7.293LysGlu: 7.293 ± 1.041
1.216LysPhe: 1.216 ± 0.617
3.647LysGly: 3.647 ± 1.693
2.836LysHis: 2.836 ± 0.449
5.673LysIle: 5.673 ± 0.581
4.862LysLys: 4.862 ± 1.167
6.888LysLeu: 6.888 ± 1.587
2.431LysMet: 2.431 ± 0.431
3.647LysAsn: 3.647 ± 0.801
1.216LysPro: 1.216 ± 0.617
1.216LysGln: 1.216 ± 0.617
4.862LysArg: 4.862 ± 1.381
4.862LysSer: 4.862 ± 2.808
1.216LysThr: 1.216 ± 0.49
3.647LysVal: 3.647 ± 2.022
0.0LysTrp: 0.0 ± 0.0
1.621LysTyr: 1.621 ± 0.527
0.0LysXaa: 0.0 ± 0.0
Leu
5.673LeuAla: 5.673 ± 1.642
2.431LeuCys: 2.431 ± 0.809
7.699LeuAsp: 7.699 ± 1.954
6.483LeuGlu: 6.483 ± 1.403
4.457LeuPhe: 4.457 ± 0.969
9.724LeuGly: 9.724 ± 2.419
3.647LeuHis: 3.647 ± 1.289
3.647LeuIle: 3.647 ± 0.594
10.94LeuLys: 10.94 ± 2.53
8.509LeuLeu: 8.509 ± 2.266
2.836LeuMet: 2.836 ± 1.295
3.647LeuAsn: 3.647 ± 1.133
2.431LeuPro: 2.431 ± 1.234
2.836LeuGln: 2.836 ± 0.621
6.483LeuArg: 6.483 ± 0.88
10.13LeuSer: 10.13 ± 2.178
4.052LeuThr: 4.052 ± 1.014
7.293LeuVal: 7.293 ± 2.577
0.0LeuTrp: 0.0 ± 0.0
2.431LeuTyr: 2.431 ± 1.234
0.0LeuXaa: 0.0 ± 0.0
Met
2.026MetAla: 2.026 ± 1.028
0.81MetCys: 0.81 ± 1.501
2.026MetAsp: 2.026 ± 2.367
2.431MetGlu: 2.431 ± 0.595
1.621MetPhe: 1.621 ± 0.639
2.431MetGly: 2.431 ± 0.98
1.216MetHis: 1.216 ± 1.419
2.431MetIle: 2.431 ± 0.765
1.621MetLys: 1.621 ± 0.822
3.241MetLeu: 3.241 ± 1.163
0.405MetMet: 0.405 ± 0.795
0.405MetAsn: 0.405 ± 0.795
0.81MetPro: 0.81 ± 0.623
1.216MetGln: 1.216 ± 1.128
1.621MetArg: 1.621 ± 0.568
0.81MetSer: 0.81 ± 0.411
1.216MetThr: 1.216 ± 0.564
0.81MetVal: 0.81 ± 0.411
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.216AsnAla: 1.216 ± 0.539
0.81AsnCys: 0.81 ± 0.695
0.405AsnAsp: 0.405 ± 0.622
2.026AsnGlu: 2.026 ± 0.641
0.405AsnPhe: 0.405 ± 0.206
1.621AsnGly: 1.621 ± 0.542
2.431AsnHis: 2.431 ± 0.8
3.241AsnIle: 3.241 ± 2.052
2.026AsnLys: 2.026 ± 2.026
7.293AsnLeu: 7.293 ± 2.465
0.81AsnMet: 0.81 ± 0.411
1.621AsnAsn: 1.621 ± 0.663
2.026AsnPro: 2.026 ± 0.641
1.621AsnGln: 1.621 ± 0.822
1.621AsnArg: 1.621 ± 0.527
1.621AsnSer: 1.621 ± 0.568
1.621AsnThr: 1.621 ± 0.822
4.457AsnVal: 4.457 ± 1.187
0.0AsnTrp: 0.0 ± 0.0
3.241AsnTyr: 3.241 ± 1.387
0.0AsnXaa: 0.0 ± 0.0
Pro
2.836ProAla: 2.836 ± 1.86
0.0ProCys: 0.0 ± 0.0
2.431ProAsp: 2.431 ± 1.071
4.457ProGlu: 4.457 ± 1.448
1.621ProPhe: 1.621 ± 0.639
2.026ProGly: 2.026 ± 1.028
0.81ProHis: 0.81 ± 0.695
1.621ProIle: 1.621 ± 0.822
2.026ProLys: 2.026 ± 0.657
3.647ProLeu: 3.647 ± 0.801
0.81ProMet: 0.81 ± 0.631
0.81ProAsn: 0.81 ± 0.411
1.621ProPro: 1.621 ± 0.568
1.621ProGln: 1.621 ± 0.568
1.621ProArg: 1.621 ± 0.822
2.836ProSer: 2.836 ± 0.449
2.026ProThr: 2.026 ± 0.738
2.431ProVal: 2.431 ± 0.765
0.405ProTrp: 0.405 ± 0.206
2.026ProTyr: 2.026 ± 1.028
0.0ProXaa: 0.0 ± 0.0
Gln
1.216GlnAla: 1.216 ± 0.49
1.621GlnCys: 1.621 ± 0.822
1.216GlnAsp: 1.216 ± 0.49
1.216GlnGlu: 1.216 ± 0.617
0.81GlnPhe: 0.81 ± 0.411
1.621GlnGly: 1.621 ± 0.663
0.81GlnHis: 0.81 ± 0.411
1.216GlnIle: 1.216 ± 0.617
2.026GlnLys: 2.026 ± 1.028
2.431GlnLeu: 2.431 ± 0.712
1.621GlnMet: 1.621 ± 0.639
0.405GlnAsn: 0.405 ± 0.206
1.621GlnPro: 1.621 ± 0.663
0.0GlnGln: 0.0 ± 0.0
2.431GlnArg: 2.431 ± 2.335
1.621GlnSer: 1.621 ± 0.963
0.405GlnThr: 0.405 ± 0.206
3.241GlnVal: 3.241 ± 1.719
0.405GlnTrp: 0.405 ± 0.206
0.81GlnTyr: 0.81 ± 0.521
0.0GlnXaa: 0.0 ± 0.0
Arg
4.862ArgAla: 4.862 ± 1.604
0.81ArgCys: 0.81 ± 0.985
1.621ArgAsp: 1.621 ± 0.822
2.026ArgGlu: 2.026 ± 0.657
3.647ArgPhe: 3.647 ± 1.363
2.026ArgGly: 2.026 ± 1.482
0.0ArgHis: 0.0 ± 0.0
2.026ArgIle: 2.026 ± 0.638
3.241ArgLys: 3.241 ± 1.084
6.888ArgLeu: 6.888 ± 1.812
2.026ArgMet: 2.026 ± 0.864
4.052ArgAsn: 4.052 ± 0.994
0.81ArgPro: 0.81 ± 0.411
0.81ArgGln: 0.81 ± 0.631
2.836ArgArg: 2.836 ± 0.821
4.457ArgSer: 4.457 ± 0.82
2.836ArgThr: 2.836 ± 0.749
4.862ArgVal: 4.862 ± 0.493
0.405ArgTrp: 0.405 ± 0.206
2.836ArgTyr: 2.836 ± 1.764
0.0ArgXaa: 0.0 ± 0.0
Ser
5.267SerAla: 5.267 ± 1.389
1.216SerCys: 1.216 ± 0.648
6.078SerAsp: 6.078 ± 1.326
6.078SerGlu: 6.078 ± 0.898
4.052SerPhe: 4.052 ± 0.574
4.457SerGly: 4.457 ± 2.51
2.431SerHis: 2.431 ± 0.809
4.052SerIle: 4.052 ± 0.55
6.483SerLys: 6.483 ± 1.426
4.457SerLeu: 4.457 ± 1.587
0.405SerMet: 0.405 ± 0.206
5.267SerAsn: 5.267 ± 1.651
1.621SerPro: 1.621 ± 0.937
2.836SerGln: 2.836 ± 0.865
4.862SerArg: 4.862 ± 0.691
7.699SerSer: 7.699 ± 0.978
4.457SerThr: 4.457 ± 1.039
4.862SerVal: 4.862 ± 3.461
0.0SerTrp: 0.0 ± 0.0
2.431SerTyr: 2.431 ± 0.857
0.0SerXaa: 0.0 ± 0.0
Thr
2.026ThrAla: 2.026 ± 1.028
0.81ThrCys: 0.81 ± 0.623
2.026ThrAsp: 2.026 ± 1.335
2.431ThrGlu: 2.431 ± 0.8
3.241ThrPhe: 3.241 ± 1.645
2.431ThrGly: 2.431 ± 1.234
0.81ThrHis: 0.81 ± 0.411
3.647ThrIle: 3.647 ± 0.801
2.026ThrLys: 2.026 ± 0.99
6.888ThrLeu: 6.888 ± 1.85
1.621ThrMet: 1.621 ± 1.292
1.621ThrAsn: 1.621 ± 0.568
1.216ThrPro: 1.216 ± 0.951
1.216ThrGln: 1.216 ± 0.648
3.647ThrArg: 3.647 ± 2.058
1.216ThrSer: 1.216 ± 1.095
1.216ThrThr: 1.216 ± 0.49
2.836ThrVal: 2.836 ± 0.981
0.405ThrTrp: 0.405 ± 0.206
1.216ThrTyr: 1.216 ± 0.539
0.0ThrXaa: 0.0 ± 0.0
Val
3.241ValAla: 3.241 ± 2.479
1.216ValCys: 1.216 ± 2.263
4.052ValAsp: 4.052 ± 1.314
5.673ValGlu: 5.673 ± 1.234
3.241ValPhe: 3.241 ± 1.278
3.241ValGly: 3.241 ± 1.084
1.216ValHis: 1.216 ± 0.617
4.052ValIle: 4.052 ± 0.994
3.241ValLys: 3.241 ± 1.089
5.267ValLeu: 5.267 ± 1.459
2.836ValMet: 2.836 ± 3.299
2.836ValAsn: 2.836 ± 0.621
2.026ValPro: 2.026 ± 1.028
2.026ValGln: 2.026 ± 0.638
2.431ValArg: 2.431 ± 1.206
6.078ValSer: 6.078 ± 1.835
2.026ValThr: 2.026 ± 1.674
5.673ValVal: 5.673 ± 1.783
0.0ValTrp: 0.0 ± 0.0
2.431ValTyr: 2.431 ± 0.98
0.0ValXaa: 0.0 ± 0.0
Trp
0.81TrpAla: 0.81 ± 0.411
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.405TrpPhe: 0.405 ± 0.206
0.405TrpGly: 0.405 ± 0.206
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.405TrpLys: 0.405 ± 0.754
0.405TrpLeu: 0.405 ± 0.206
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.216TrpPro: 1.216 ± 0.617
0.0TrpGln: 0.0 ± 0.0
0.405TrpArg: 0.405 ± 0.206
0.81TrpSer: 0.81 ± 0.411
0.405TrpThr: 0.405 ± 0.206
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.621TyrAla: 1.621 ± 0.822
0.405TyrCys: 0.405 ± 0.206
1.621TyrAsp: 1.621 ± 0.568
3.241TyrGlu: 3.241 ± 0.689
2.431TyrPhe: 2.431 ± 1.234
2.026TyrGly: 2.026 ± 0.591
1.216TyrHis: 1.216 ± 0.564
2.026TyrIle: 2.026 ± 0.657
1.621TyrLys: 1.621 ± 0.937
3.647TyrLeu: 3.647 ± 1.546
0.81TyrMet: 0.81 ± 0.411
2.431TyrAsn: 2.431 ± 1.431
2.026TyrPro: 2.026 ± 1.035
2.026TyrGln: 2.026 ± 0.657
0.405TyrArg: 0.405 ± 0.206
3.647TyrSer: 3.647 ± 1.346
2.026TyrThr: 2.026 ± 0.641
2.026TyrVal: 2.026 ± 0.692
0.405TyrTrp: 0.405 ± 0.206
0.81TyrTyr: 0.81 ± 0.411
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2469 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski