Amino acid dipepetide frequency for Youngimonas vesicularis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.88AlaAla: 15.88 ± 0.185	1.058AlaCys: 1.058 ± 0.035	7.035AlaAsp: 7.035 ± 0.101	8.157AlaGlu: 8.157 ± 0.091	4.242AlaPhe: 4.242 ± 0.07	10.257AlaGly: 10.257 ± 0.111	2.354AlaHis: 2.354 ± 0.047	5.798AlaIle: 5.798 ± 0.072	4.291AlaLys: 4.291 ± 0.07	13.59AlaLeu: 13.59 ± 0.125	3.752AlaMet: 3.752 ± 0.061	2.819AlaAsn: 2.819 ± 0.051	5.576AlaPro: 5.576 ± 0.086	4.907AlaGln: 4.907 ± 0.063	8.494AlaArg: 8.494 ± 0.087	5.436AlaSer: 5.436 ± 0.071	5.741AlaThr: 5.741 ± 0.074	8.078AlaVal: 8.078 ± 0.095	1.42AlaTrp: 1.42 ± 0.035	2.594AlaTyr: 2.594 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.036CysAla: 1.036 ± 0.029	0.107CysCys: 0.107 ± 0.01	0.613CysAsp: 0.613 ± 0.022	0.414CysGlu: 0.414 ± 0.02	0.342CysPhe: 0.342 ± 0.018	0.933CysGly: 0.933 ± 0.032	0.284CysHis: 0.284 ± 0.018	0.39CysIle: 0.39 ± 0.02	0.253CysLys: 0.253 ± 0.014	0.839CysLeu: 0.839 ± 0.028	0.2CysMet: 0.2 ± 0.014	0.24CysAsn: 0.24 ± 0.014	0.552CysPro: 0.552 ± 0.025	0.246CysGln: 0.246 ± 0.016	0.552CysArg: 0.552 ± 0.023	0.461CysSer: 0.461 ± 0.021	0.435CysThr: 0.435 ± 0.02	0.622CysVal: 0.622 ± 0.026	0.101CysTrp: 0.101 ± 0.01	0.211CysTyr: 0.211 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.029AspAla: 7.029 ± 0.083	0.541AspCys: 0.541 ± 0.021	3.313AspAsp: 3.313 ± 0.075	3.549AspGlu: 3.549 ± 0.059	2.275AspPhe: 2.275 ± 0.042	5.627AspGly: 5.627 ± 0.085	1.33AspHis: 1.33 ± 0.037	3.005AspIle: 3.005 ± 0.056	1.876AspLys: 1.876 ± 0.041	6.347AspLeu: 6.347 ± 0.079	1.782AspMet: 1.782 ± 0.038	1.288AspAsn: 1.288 ± 0.034	3.468AspPro: 3.468 ± 0.061	2.136AspGln: 2.136 ± 0.045	4.018AspArg: 4.018 ± 0.068	2.196AspSer: 2.196 ± 0.046	3.164AspThr: 3.164 ± 0.08	4.162AspVal: 4.162 ± 0.061	1.193AspTrp: 1.193 ± 0.033	1.612AspTyr: 1.612 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.753GluAla: 7.753 ± 0.095	0.391GluCys: 0.391 ± 0.021	3.221GluAsp: 3.221 ± 0.062	3.329GluGlu: 3.329 ± 0.059	1.886GluPhe: 1.886 ± 0.046	4.839GluGly: 4.839 ± 0.071	1.119GluHis: 1.119 ± 0.033	3.512GluIle: 3.512 ± 0.058	2.307GluLys: 2.307 ± 0.047	5.271GluLeu: 5.271 ± 0.074	1.861GluMet: 1.861 ± 0.045	1.787GluAsn: 1.787 ± 0.038	2.47GluPro: 2.47 ± 0.062	2.057GluGln: 2.057 ± 0.042	4.102GluArg: 4.102 ± 0.067	1.93GluSer: 1.93 ± 0.045	3.654GluThr: 3.654 ± 0.05	4.281GluVal: 4.281 ± 0.062	0.735GluTrp: 0.735 ± 0.027	1.154GluTyr: 1.154 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.409PheAla: 4.409 ± 0.064	0.416PheCys: 0.416 ± 0.019	2.755PheAsp: 2.755 ± 0.047	2.059PheGlu: 2.059 ± 0.048	1.437PhePhe: 1.437 ± 0.044	3.634PheGly: 3.634 ± 0.062	0.771PheHis: 0.771 ± 0.029	1.555PheIle: 1.555 ± 0.042	0.979PheLys: 0.979 ± 0.032	3.467PheLeu: 3.467 ± 0.067	0.906PheMet: 0.906 ± 0.029	1.103PheAsn: 1.103 ± 0.033	1.544PhePro: 1.544 ± 0.037	1.125PheGln: 1.125 ± 0.034	2.192PheArg: 2.192 ± 0.045	2.061PheSer: 2.061 ± 0.048	2.107PheThr: 2.107 ± 0.044	2.713PheVal: 2.713 ± 0.049	0.55PheTrp: 0.55 ± 0.019	0.899PheTyr: 0.899 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.951GlyAla: 9.951 ± 0.116	0.827GlyCys: 0.827 ± 0.029	4.825GlyAsp: 4.825 ± 0.094	4.53GlyGlu: 4.53 ± 0.072	3.641GlyPhe: 3.641 ± 0.062	7.624GlyGly: 7.624 ± 0.141	1.989GlyHis: 1.989 ± 0.041	4.526GlyIle: 4.526 ± 0.065	3.506GlyLys: 3.506 ± 0.067	9.367GlyLeu: 9.367 ± 0.119	2.807GlyMet: 2.807 ± 0.05	2.344GlyAsn: 2.344 ± 0.069	3.609GlyPro: 3.609 ± 0.068	3.476GlyGln: 3.476 ± 0.062	5.433GlyArg: 5.433 ± 0.086	4.092GlySer: 4.092 ± 0.065	4.626GlyThr: 4.626 ± 0.073	6.649GlyVal: 6.649 ± 0.072	1.474GlyTrp: 1.474 ± 0.034	2.378GlyTyr: 2.378 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.346HisAla: 2.346 ± 0.053	0.236HisCys: 0.236 ± 0.014	1.246HisAsp: 1.246 ± 0.029	1.052HisGlu: 1.052 ± 0.028	0.867HisPhe: 0.867 ± 0.026	1.961HisGly: 1.961 ± 0.046	0.588HisHis: 0.588 ± 0.023	0.961HisIle: 0.961 ± 0.034	0.603HisLys: 0.603 ± 0.022	2.199HisLeu: 2.199 ± 0.046	0.578HisMet: 0.578 ± 0.021	0.503HisAsn: 0.503 ± 0.017	1.404HisPro: 1.404 ± 0.036	0.624HisGln: 0.624 ± 0.023	1.327HisArg: 1.327 ± 0.036	0.94HisSer: 0.94 ± 0.028	0.923HisThr: 0.923 ± 0.029	1.546HisVal: 1.546 ± 0.038	0.35HisTrp: 0.35 ± 0.018	0.575HisTyr: 0.575 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.835IleAla: 6.835 ± 0.078	0.617IleCys: 0.617 ± 0.022	3.255IleAsp: 3.255 ± 0.053	3.437IleGlu: 3.437 ± 0.059	1.72IlePhe: 1.72 ± 0.04	4.778IleGly: 4.778 ± 0.065	0.985IleHis: 0.985 ± 0.029	2.146IleIle: 2.146 ± 0.046	1.479IleLys: 1.479 ± 0.039	4.858IleLeu: 4.858 ± 0.069	1.082IleMet: 1.082 ± 0.036	1.367IleAsn: 1.367 ± 0.034	2.504IlePro: 2.504 ± 0.044	1.417IleGln: 1.417 ± 0.033	3.341IleArg: 3.341 ± 0.053	2.982IleSer: 2.982 ± 0.057	2.922IleThr: 2.922 ± 0.053	3.795IleVal: 3.795 ± 0.075	0.75IleTrp: 0.75 ± 0.029	1.239IleTyr: 1.239 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.176LysAla: 4.176 ± 0.069	0.199LysCys: 0.199 ± 0.015	1.894LysAsp: 1.894 ± 0.048	1.672LysGlu: 1.672 ± 0.044	1.02LysPhe: 1.02 ± 0.037	3.023LysGly: 3.023 ± 0.048	0.657LysHis: 0.657 ± 0.024	1.86LysIle: 1.86 ± 0.045	1.394LysLys: 1.394 ± 0.045	3.388LysLeu: 3.388 ± 0.06	1.078LysMet: 1.078 ± 0.026	0.888LysAsn: 0.888 ± 0.031	2.04LysPro: 2.04 ± 0.051	1.048LysGln: 1.048 ± 0.031	2.42LysArg: 2.42 ± 0.047	1.957LysSer: 1.957 ± 0.043	2.086LysThr: 2.086 ± 0.047	2.482LysVal: 2.482 ± 0.051	0.422LysTrp: 0.422 ± 0.022	0.765LysTyr: 0.765 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	12.756LeuAla: 12.756 ± 0.132	0.908LeuCys: 0.908 ± 0.026	6.065LeuAsp: 6.065 ± 0.094	5.463LeuGlu: 5.463 ± 0.068	3.457LeuPhe: 3.457 ± 0.071	8.462LeuGly: 8.462 ± 0.109	1.995LeuHis: 1.995 ± 0.045	5.354LeuIle: 5.354 ± 0.089	3.527LeuLys: 3.527 ± 0.056	9.034LeuLeu: 9.034 ± 0.121	2.766LeuMet: 2.766 ± 0.045	2.9LeuAsn: 2.9 ± 0.045	5.652LeuPro: 5.652 ± 0.073	2.819LeuGln: 2.819 ± 0.05	6.926LeuArg: 6.926 ± 0.089	6.795LeuSer: 6.795 ± 0.077	6.293LeuThr: 6.293 ± 0.078	6.747LeuVal: 6.747 ± 0.09	1.31LeuTrp: 1.31 ± 0.042	1.998LeuTyr: 1.998 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	3.559MetAla: 3.559 ± 0.064	0.198MetCys: 0.198 ± 0.014	1.535MetAsp: 1.535 ± 0.035	1.407MetGlu: 1.407 ± 0.033	0.878MetPhe: 0.878 ± 0.031	2.508MetGly: 2.508 ± 0.055	0.542MetHis: 0.542 ± 0.022	1.581MetIle: 1.581 ± 0.04	1.177MetLys: 1.177 ± 0.034	2.692MetLeu: 2.692 ± 0.043	0.889MetMet: 0.889 ± 0.029	0.837MetAsn: 0.837 ± 0.028	1.584MetPro: 1.584 ± 0.034	1.107MetGln: 1.107 ± 0.028	1.952MetArg: 1.952 ± 0.045	1.804MetSer: 1.804 ± 0.04	2.161MetThr: 2.161 ± 0.04	1.844MetVal: 1.844 ± 0.042	0.275MetTrp: 0.275 ± 0.015	0.403MetTyr: 0.403 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.226AsnAla: 3.226 ± 0.056	0.303AsnCys: 0.303 ± 0.018	1.64AsnAsp: 1.64 ± 0.084	1.231AsnGlu: 1.231 ± 0.031	0.973AsnPhe: 0.973 ± 0.034	2.655AsnGly: 2.655 ± 0.056	0.497AsnHis: 0.497 ± 0.018	1.394AsnIle: 1.394 ± 0.039	0.815AsnLys: 0.815 ± 0.025	2.538AsnLeu: 2.538 ± 0.04	0.744AsnMet: 0.744 ± 0.029	0.686AsnAsn: 0.686 ± 0.023	1.916AsnPro: 1.916 ± 0.037	0.704AsnGln: 0.704 ± 0.024	1.796AsnArg: 1.796 ± 0.037	1.25AsnSer: 1.25 ± 0.033	1.344AsnThr: 1.344 ± 0.037	1.909AsnVal: 1.909 ± 0.043	0.414AsnTrp: 0.414 ± 0.021	0.673AsnTyr: 0.673 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.795ProAla: 5.795 ± 0.083	0.354ProCys: 0.354 ± 0.018	3.868ProAsp: 3.868 ± 0.062	4.055ProGlu: 4.055 ± 0.061	1.893ProPhe: 1.893 ± 0.04	4.431ProGly: 4.431 ± 0.064	1.065ProHis: 1.065 ± 0.032	2.316ProIle: 2.316 ± 0.047	1.832ProLys: 1.832 ± 0.043	4.642ProLeu: 4.642 ± 0.07	1.348ProMet: 1.348 ± 0.031	1.37ProAsn: 1.37 ± 0.032	2.064ProPro: 2.064 ± 0.049	1.874ProGln: 1.874 ± 0.041	2.707ProArg: 2.707 ± 0.049	2.47ProSer: 2.47 ± 0.04	2.354ProThr: 2.354 ± 0.044	4.311ProVal: 4.311 ± 0.072	0.626ProTrp: 0.626 ± 0.024	1.185ProTyr: 1.185 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.484GlnAla: 4.484 ± 0.063	0.212GlnCys: 0.212 ± 0.013	1.873GlnAsp: 1.873 ± 0.037	1.585GlnGlu: 1.585 ± 0.044	1.12GlnPhe: 1.12 ± 0.032	2.81GlnGly: 2.81 ± 0.051	0.676GlnHis: 0.676 ± 0.027	2.26GlnIle: 2.26 ± 0.05	1.231GlnLys: 1.231 ± 0.032	3.102GlnLeu: 3.102 ± 0.056	1.278GlnMet: 1.278 ± 0.038	0.949GlnAsn: 0.949 ± 0.028	1.793GlnPro: 1.793 ± 0.044	1.226GlnGln: 1.226 ± 0.037	2.211GlnArg: 2.211 ± 0.049	1.692GlnSer: 1.692 ± 0.038	1.987GlnThr: 1.987 ± 0.045	2.663GlnVal: 2.663 ± 0.048	0.411GlnTrp: 0.411 ± 0.019	0.639GlnTyr: 0.639 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	7.906ArgAla: 7.906 ± 0.09	0.48ArgCys: 0.48 ± 0.021	4.076ArgAsp: 4.076 ± 0.058	3.723ArgGlu: 3.723 ± 0.065	2.639ArgPhe: 2.639 ± 0.053	4.512ArgGly: 4.512 ± 0.062	1.501ArgHis: 1.501 ± 0.039	3.774ArgIle: 3.774 ± 0.058	2.453ArgLys: 2.453 ± 0.047	7.153ArgLeu: 7.153 ± 0.091	2.011ArgMet: 2.011 ± 0.042	1.842ArgAsn: 1.842 ± 0.042	3.224ArgPro: 3.224 ± 0.064	2.33ArgGln: 2.33 ± 0.052	4.548ArgArg: 4.548 ± 0.073	3.031ArgSer: 3.031 ± 0.057	3.022ArgThr: 3.022 ± 0.047	4.615ArgVal: 4.615 ± 0.068	0.937ArgTrp: 0.937 ± 0.032	1.508ArgTyr: 1.508 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.618SerAla: 5.618 ± 0.088	0.449SerCys: 0.449 ± 0.022	3.217SerAsp: 3.217 ± 0.059	2.745SerGlu: 2.745 ± 0.052	2.097SerPhe: 2.097 ± 0.043	5.337SerGly: 5.337 ± 0.069	1.049SerHis: 1.049 ± 0.034	2.443SerIle: 2.443 ± 0.044	1.558SerLys: 1.558 ± 0.037	5.089SerLeu: 5.089 ± 0.074	1.361SerMet: 1.361 ± 0.033	1.337SerAsn: 1.337 ± 0.036	2.406SerPro: 2.406 ± 0.044	1.566SerGln: 1.566 ± 0.037	3.067SerArg: 3.067 ± 0.054	2.43SerSer: 2.43 ± 0.053	2.442SerThr: 2.442 ± 0.045	3.847SerVal: 3.847 ± 0.068	0.732SerTrp: 0.732 ± 0.028	1.268SerTyr: 1.268 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.063ThrAla: 6.063 ± 0.075	0.498ThrCys: 0.498 ± 0.025	3.11ThrAsp: 3.11 ± 0.058	2.961ThrGlu: 2.961 ± 0.053	1.95ThrPhe: 1.95 ± 0.038	5.55ThrGly: 5.55 ± 0.073	1.19ThrHis: 1.19 ± 0.036	2.649ThrIle: 2.649 ± 0.054	1.565ThrLys: 1.565 ± 0.04	6.056ThrLeu: 6.056 ± 0.084	1.263ThrMet: 1.263 ± 0.036	1.33ThrAsn: 1.33 ± 0.034	3.425ThrPro: 3.425 ± 0.063	1.843ThrGln: 1.843 ± 0.036	3.619ThrArg: 3.619 ± 0.057	2.56ThrSer: 2.56 ± 0.052	2.704ThrThr: 2.704 ± 0.056	4.206ThrVal: 4.206 ± 0.066	0.672ThrTrp: 0.672 ± 0.026	1.313ThrTyr: 1.313 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	8.617ValAla: 8.617 ± 0.103	0.667ValCys: 0.667 ± 0.025	3.939ValAsp: 3.939 ± 0.055	4.354ValGlu: 4.354 ± 0.063	2.795ValPhe: 2.795 ± 0.052	5.339ValGly: 5.339 ± 0.07	1.33ValHis: 1.33 ± 0.038	4.398ValIle: 4.398 ± 0.068	2.463ValLys: 2.463 ± 0.051	7.653ValLeu: 7.653 ± 0.1	2.246ValMet: 2.246 ± 0.053	2.081ValAsn: 2.081 ± 0.04	3.542ValPro: 3.542 ± 0.06	2.379ValGln: 2.379 ± 0.043	4.05ValArg: 4.05 ± 0.057	4.085ValSer: 4.085 ± 0.065	4.657ValThr: 4.657 ± 0.079	5.655ValVal: 5.655 ± 0.08	0.974ValTrp: 0.974 ± 0.034	1.515ValTyr: 1.515 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.417TrpAla: 1.417 ± 0.036	0.126TrpCys: 0.126 ± 0.01	0.802TrpAsp: 0.802 ± 0.024	0.646TrpGlu: 0.646 ± 0.024	0.545TrpPhe: 0.545 ± 0.024	1.115TrpGly: 1.115 ± 0.038	0.347TrpHis: 0.347 ± 0.016	0.65TrpIle: 0.65 ± 0.025	0.503TrpLys: 0.503 ± 0.022	1.624TrpLeu: 1.624 ± 0.041	0.449TrpMet: 0.449 ± 0.02	0.414TrpAsn: 0.414 ± 0.021	0.707TrpPro: 0.707 ± 0.024	0.61TrpGln: 0.61 ± 0.024	1.028TrpArg: 1.028 ± 0.034	0.728TrpSer: 0.728 ± 0.024	0.777TrpThr: 0.777 ± 0.025	0.966TrpVal: 0.966 ± 0.036	0.193TrpTrp: 0.193 ± 0.013	0.275TrpTyr: 0.275 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.624TyrAla: 2.624 ± 0.053	0.241TyrCys: 0.241 ± 0.014	1.63TyrAsp: 1.63 ± 0.039	1.293TyrGlu: 1.293 ± 0.033	0.907TyrPhe: 0.907 ± 0.029	2.279TyrGly: 2.279 ± 0.049	0.561TyrHis: 0.561 ± 0.021	0.936TyrIle: 0.936 ± 0.029	0.658TyrLys: 0.658 ± 0.025	2.316TyrLeu: 2.316 ± 0.047	0.532TyrMet: 0.532 ± 0.022	0.624TyrAsn: 0.624 ± 0.022	1.08TyrPro: 1.08 ± 0.031	0.707TyrGln: 0.707 ± 0.023	1.501TyrArg: 1.501 ± 0.036	1.158TyrSer: 1.158 ± 0.032	1.13TyrThr: 1.13 ± 0.032	1.647TyrVal: 1.647 ± 0.035	0.381TyrTrp: 0.381 ± 0.017	0.591TyrTyr: 0.591 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3652 proteins (1143577 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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