Amino acid dipepetide frequency for Pan troglodytes polyomavirus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.923AlaAla: 4.923 ± 0.741
0.0AlaCys: 0.0 ± 0.0
4.308AlaAsp: 4.308 ± 1.615
1.231AlaGlu: 1.231 ± 0.583
2.462AlaPhe: 2.462 ± 0.371
2.462AlaGly: 2.462 ± 0.371
0.615AlaHis: 0.615 ± 0.375
4.923AlaIle: 4.923 ± 0.716
3.692AlaLys: 3.692 ± 1.966
6.769AlaLeu: 6.769 ± 1.358
0.0AlaMet: 0.0 ± 0.0
3.077AlaAsn: 3.077 ± 0.896
0.615AlaPro: 0.615 ± 0.584
3.077AlaGln: 3.077 ± 1.675
4.308AlaArg: 4.308 ± 2.288
4.923AlaSer: 4.923 ± 1.945
4.308AlaThr: 4.308 ± 1.88
5.538AlaVal: 5.538 ± 1.096
0.615AlaTrp: 0.615 ± 0.375
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.462CysAla: 2.462 ± 1.011
0.0CysCys: 0.0 ± 0.0
1.231CysAsp: 1.231 ± 0.751
1.231CysGlu: 1.231 ± 0.751
1.231CysPhe: 1.231 ± 1.359
1.231CysGly: 1.231 ± 0.506
0.615CysHis: 0.615 ± 0.679
0.615CysIle: 0.615 ± 0.679
3.692CysLys: 3.692 ± 1.129
3.077CysLeu: 3.077 ± 1.382
0.615CysMet: 0.615 ± 0.679
1.231CysAsn: 1.231 ± 0.751
1.231CysPro: 1.231 ± 0.506
0.615CysGln: 0.615 ± 0.375
0.0CysArg: 0.0 ± 0.0
2.462CysSer: 2.462 ± 1.011
1.846CysThr: 1.846 ± 0.672
0.615CysVal: 0.615 ± 0.679
0.0CysTrp: 0.0 ± 0.0
1.846CysTyr: 1.846 ± 0.667
0.0CysXaa: 0.0 ± 0.0
Asp
1.846AspAla: 1.846 ± 1.142
0.0AspCys: 0.0 ± 0.0
2.462AspAsp: 2.462 ± 0.964
4.308AspGlu: 4.308 ± 0.39
3.077AspPhe: 3.077 ± 1.877
4.308AspGly: 4.308 ± 1.396
0.615AspHis: 0.615 ± 0.375
5.538AspIle: 5.538 ± 1.133
6.154AspLys: 6.154 ± 0.901
4.308AspLeu: 4.308 ± 1.883
2.462AspMet: 2.462 ± 1.083
3.692AspAsn: 3.692 ± 1.254
3.692AspPro: 3.692 ± 0.668
1.231AspGln: 1.231 ± 0.506
1.231AspArg: 1.231 ± 0.583
3.692AspSer: 3.692 ± 1.653
0.615AspThr: 0.615 ± 0.674
2.462AspVal: 2.462 ± 0.371
1.846AspTrp: 1.846 ± 1.503
1.846AspTyr: 1.846 ± 0.712
0.0AspXaa: 0.0 ± 0.0
Glu
6.154GluAla: 6.154 ± 2.495
1.846GluCys: 1.846 ± 0.788
4.308GluAsp: 4.308 ± 0.914
5.538GluGlu: 5.538 ± 1.514
1.846GluPhe: 1.846 ± 0.712
4.308GluGly: 4.308 ± 1.768
0.615GluHis: 0.615 ± 0.679
1.846GluIle: 1.846 ± 0.672
6.154GluLys: 6.154 ± 2.763
8.0GluLeu: 8.0 ± 2.114
1.846GluMet: 1.846 ± 0.788
4.308GluAsn: 4.308 ± 1.768
1.846GluPro: 1.846 ± 1.026
2.462GluGln: 2.462 ± 0.745
1.231GluArg: 1.231 ± 0.751
5.538GluSer: 5.538 ± 1.133
1.846GluThr: 1.846 ± 1.203
4.308GluVal: 4.308 ± 1.721
0.615GluTrp: 0.615 ± 0.375
2.462GluTyr: 2.462 ± 0.745
0.0GluXaa: 0.0 ± 0.0
Phe
1.846PheAla: 1.846 ± 1.126
1.846PheCys: 1.846 ± 0.788
2.462PheAsp: 2.462 ± 1.266
2.462PheGlu: 2.462 ± 1.502
1.231PhePhe: 1.231 ± 0.506
1.231PheGly: 1.231 ± 1.169
1.846PheHis: 1.846 ± 0.712
2.462PheIle: 2.462 ± 1.248
3.692PheLys: 3.692 ± 1.725
3.077PheLeu: 3.077 ± 0.671
1.846PheMet: 1.846 ± 1.258
3.077PheAsn: 3.077 ± 0.97
3.692PhePro: 3.692 ± 1.154
1.846PheGln: 1.846 ± 1.203
0.615PheArg: 0.615 ± 0.375
5.538PheSer: 5.538 ± 0.913
3.077PheThr: 3.077 ± 1.129
1.846PheVal: 1.846 ± 1.126
0.0PheTrp: 0.0 ± 0.0
1.231PheTyr: 1.231 ± 0.583
0.0PheXaa: 0.0 ± 0.0
Gly
1.846GlyAla: 1.846 ± 1.203
0.615GlyCys: 0.615 ± 0.375
3.077GlyAsp: 3.077 ± 0.92
4.923GlyGlu: 4.923 ± 1.226
2.462GlyPhe: 2.462 ± 1.659
5.538GlyGly: 5.538 ± 1.644
0.615GlyHis: 0.615 ± 0.674
3.077GlyIle: 3.077 ± 1.103
1.846GlyLys: 1.846 ± 1.126
7.385GlyLeu: 7.385 ± 1.949
1.231GlyMet: 1.231 ± 0.583
2.462GlyAsn: 2.462 ± 1.06
4.923GlyPro: 4.923 ± 1.125
3.692GlyGln: 3.692 ± 0.668
1.231GlyArg: 1.231 ± 0.583
2.462GlySer: 2.462 ± 0.858
2.462GlyThr: 2.462 ± 0.858
5.538GlyVal: 5.538 ± 2.611
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.846HisAla: 1.846 ± 1.203
0.0HisCys: 0.0 ± 0.0
0.615HisAsp: 0.615 ± 0.375
0.615HisGlu: 0.615 ± 0.375
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
5.538HisLys: 5.538 ± 3.123
1.231HisLeu: 1.231 ± 1.359
1.846HisMet: 1.846 ± 0.672
0.0HisAsn: 0.0 ± 0.0
1.846HisPro: 1.846 ± 0.768
1.231HisGln: 1.231 ± 0.733
0.615HisArg: 0.615 ± 0.375
1.846HisSer: 1.846 ± 0.443
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.231HisTyr: 1.231 ± 0.751
0.0HisXaa: 0.0 ± 0.0
Ile
3.692IleAla: 3.692 ± 0.369
1.846IleCys: 1.846 ± 0.672
2.462IleAsp: 2.462 ± 0.613
4.308IleGlu: 4.308 ± 0.39
1.846IlePhe: 1.846 ± 0.788
1.846IleGly: 1.846 ± 1.203
0.0IleHis: 0.0 ± 0.0
2.462IleIle: 2.462 ± 1.861
2.462IleLys: 2.462 ± 0.663
6.769IleLeu: 6.769 ± 1.387
1.231IleMet: 1.231 ± 0.633
1.231IleAsn: 1.231 ± 0.733
2.462IlePro: 2.462 ± 1.023
0.0IleGln: 0.0 ± 0.0
1.846IleArg: 1.846 ± 0.672
3.077IleSer: 3.077 ± 0.6
4.308IleThr: 4.308 ± 1.425
5.538IleVal: 5.538 ± 1.0
2.462IleTrp: 2.462 ± 1.491
1.231IleTyr: 1.231 ± 0.751
0.0IleXaa: 0.0 ± 0.0
Lys
3.692LysAla: 3.692 ± 1.517
3.692LysCys: 3.692 ± 2.045
1.846LysAsp: 1.846 ± 1.126
6.769LysGlu: 6.769 ± 1.732
0.0LysPhe: 0.0 ± 0.0
4.923LysGly: 4.923 ± 1.433
1.846LysHis: 1.846 ± 0.712
4.308LysIle: 4.308 ± 1.454
8.0LysLys: 8.0 ± 0.484
1.846LysLeu: 1.846 ± 0.672
3.692LysMet: 3.692 ± 1.194
2.462LysAsn: 2.462 ± 1.011
2.462LysPro: 2.462 ± 0.964
4.308LysGln: 4.308 ± 1.396
6.769LysArg: 6.769 ± 1.529
2.462LysSer: 2.462 ± 1.06
4.308LysThr: 4.308 ± 1.619
3.077LysVal: 3.077 ± 1.382
0.0LysTrp: 0.0 ± 0.0
4.923LysTyr: 4.923 ± 1.216
0.0LysXaa: 0.0 ± 0.0
Leu
3.692LeuAla: 3.692 ± 2.571
1.846LeuCys: 1.846 ± 0.672
8.615LeuAsp: 8.615 ± 1.779
7.385LeuGlu: 7.385 ± 0.737
6.154LeuPhe: 6.154 ± 1.2
4.308LeuGly: 4.308 ± 2.34
2.462LeuHis: 2.462 ± 1.266
6.769LeuIle: 6.769 ± 1.4
3.077LeuLys: 3.077 ± 1.382
8.0LeuLeu: 8.0 ± 2.122
3.077LeuMet: 3.077 ± 0.846
4.308LeuAsn: 4.308 ± 1.396
6.769LeuPro: 6.769 ± 0.365
4.923LeuGln: 4.923 ± 1.788
1.846LeuArg: 1.846 ± 0.667
3.692LeuSer: 3.692 ± 0.836
4.923LeuThr: 4.923 ± 2.73
3.692LeuVal: 3.692 ± 1.154
2.462LeuTrp: 2.462 ± 1.266
3.077LeuTyr: 3.077 ± 0.339
0.0LeuXaa: 0.0 ± 0.0
Met
2.462MetAla: 2.462 ± 0.978
1.231MetCys: 1.231 ± 0.633
3.077MetAsp: 3.077 ± 1.38
2.462MetGlu: 2.462 ± 0.663
1.231MetPhe: 1.231 ± 0.506
1.231MetGly: 1.231 ± 0.733
0.0MetHis: 0.0 ± 0.0
0.615MetIle: 0.615 ± 0.375
3.077MetLys: 3.077 ± 1.162
3.077MetLeu: 3.077 ± 1.182
0.615MetMet: 0.615 ± 0.512
2.462MetAsn: 2.462 ± 0.964
0.615MetPro: 0.615 ± 0.584
0.0MetGln: 0.0 ± 0.0
4.923MetArg: 4.923 ± 2.369
0.615MetSer: 0.615 ± 0.584
1.231MetThr: 1.231 ± 0.506
0.0MetVal: 0.0 ± 0.0
0.615MetTrp: 0.615 ± 0.584
0.615MetTyr: 0.615 ± 0.674
0.0MetXaa: 0.0 ± 0.0
Asn
4.923AsnAla: 4.923 ± 0.472
1.231AsnCys: 1.231 ± 0.751
1.846AsnAsp: 1.846 ± 1.126
4.308AsnGlu: 4.308 ± 1.396
2.462AsnPhe: 2.462 ± 1.06
1.231AsnGly: 1.231 ± 0.733
0.0AsnHis: 0.0 ± 0.0
1.846AsnIle: 1.846 ± 0.672
3.077AsnLys: 3.077 ± 1.877
3.692AsnLeu: 3.692 ± 1.643
2.462AsnMet: 2.462 ± 1.327
1.846AsnAsn: 1.846 ± 0.672
1.846AsnPro: 1.846 ± 1.142
2.462AsnGln: 2.462 ± 1.466
1.846AsnArg: 1.846 ± 0.768
1.846AsnSer: 1.846 ± 1.026
3.692AsnThr: 3.692 ± 1.335
4.308AsnVal: 4.308 ± 1.133
0.615AsnTrp: 0.615 ± 0.375
3.692AsnTyr: 3.692 ± 1.194
0.0AsnXaa: 0.0 ± 0.0
Pro
3.692ProAla: 3.692 ± 0.598
2.462ProCys: 2.462 ± 1.011
5.538ProAsp: 5.538 ± 1.526
1.846ProGlu: 1.846 ± 1.126
1.846ProPhe: 1.846 ± 0.788
3.692ProGly: 3.692 ± 1.495
1.231ProHis: 1.231 ± 0.506
1.846ProIle: 1.846 ± 0.672
4.308ProLys: 4.308 ± 1.615
5.538ProLeu: 5.538 ± 0.837
0.615ProMet: 0.615 ± 0.584
0.0ProAsn: 0.0 ± 0.0
5.538ProPro: 5.538 ± 2.017
1.231ProGln: 1.231 ± 0.751
1.231ProArg: 1.231 ± 1.169
4.308ProSer: 4.308 ± 1.15
3.692ProThr: 3.692 ± 0.836
4.923ProVal: 4.923 ± 1.633
0.615ProTrp: 0.615 ± 0.674
0.615ProTyr: 0.615 ± 0.584
0.0ProXaa: 0.0 ± 0.0
Gln
2.462GlnAla: 2.462 ± 0.978
0.615GlnCys: 0.615 ± 0.375
1.231GlnAsp: 1.231 ± 0.583
0.0GlnGlu: 0.0 ± 0.0
5.538GlnPhe: 5.538 ± 1.682
1.231GlnGly: 1.231 ± 0.506
1.231GlnHis: 1.231 ± 0.633
3.077GlnIle: 3.077 ± 1.247
2.462GlnLys: 2.462 ± 1.023
1.846GlnLeu: 1.846 ± 1.203
1.846GlnMet: 1.846 ± 0.862
1.846GlnAsn: 1.846 ± 0.667
1.231GlnPro: 1.231 ± 0.506
3.077GlnGln: 3.077 ± 1.38
1.231GlnArg: 1.231 ± 0.583
2.462GlnSer: 2.462 ± 1.166
3.692GlnThr: 3.692 ± 0.598
3.077GlnVal: 3.077 ± 1.566
0.0GlnTrp: 0.0 ± 0.0
1.846GlnTyr: 1.846 ± 0.443
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
1.231ArgCys: 1.231 ± 0.633
4.308ArgAsp: 4.308 ± 1.29
0.615ArgGlu: 0.615 ± 0.375
3.077ArgPhe: 3.077 ± 0.846
3.077ArgGly: 3.077 ± 0.671
0.615ArgHis: 0.615 ± 0.375
2.462ArgIle: 2.462 ± 0.613
2.462ArgLys: 2.462 ± 1.592
4.308ArgLeu: 4.308 ± 1.464
0.615ArgMet: 0.615 ± 0.584
3.692ArgAsn: 3.692 ± 1.37
0.615ArgPro: 0.615 ± 0.375
2.462ArgGln: 2.462 ± 2.126
6.769ArgArg: 6.769 ± 1.79
0.615ArgSer: 0.615 ± 0.375
1.231ArgThr: 1.231 ± 0.506
4.308ArgVal: 4.308 ± 2.011
0.615ArgTrp: 0.615 ± 0.674
2.462ArgTyr: 2.462 ± 1.466
0.0ArgXaa: 0.0 ± 0.0
Ser
4.923SerAla: 4.923 ± 1.125
3.692SerCys: 3.692 ± 0.995
3.077SerAsp: 3.077 ± 1.129
3.077SerGlu: 3.077 ± 0.896
5.538SerPhe: 5.538 ± 2.269
4.923SerGly: 4.923 ± 2.3
0.615SerHis: 0.615 ± 0.375
3.692SerIle: 3.692 ± 0.887
4.308SerLys: 4.308 ± 2.003
6.769SerLeu: 6.769 ± 2.079
0.615SerMet: 0.615 ± 0.375
2.462SerAsn: 2.462 ± 1.166
1.846SerPro: 1.846 ± 0.672
1.846SerGln: 1.846 ± 1.126
0.615SerArg: 0.615 ± 0.375
9.231SerSer: 9.231 ± 1.968
6.154SerThr: 6.154 ± 2.284
3.692SerVal: 3.692 ± 2.563
0.0SerTrp: 0.0 ± 0.0
3.077SerTyr: 3.077 ± 0.855
0.0SerXaa: 0.0 ± 0.0
Thr
3.077ThrAla: 3.077 ± 1.675
2.462ThrCys: 2.462 ± 0.964
3.077ThrAsp: 3.077 ± 2.21
5.538ThrGlu: 5.538 ± 1.096
1.231ThrPhe: 1.231 ± 0.633
3.077ThrGly: 3.077 ± 1.152
0.615ThrHis: 0.615 ± 0.674
0.615ThrIle: 0.615 ± 0.584
1.846ThrLys: 1.846 ± 1.026
4.923ThrLeu: 4.923 ± 0.478
0.615ThrMet: 0.615 ± 0.375
3.077ThrAsn: 3.077 ± 1.4
8.0ThrPro: 8.0 ± 0.855
1.231ThrGln: 1.231 ± 0.751
1.846ThrArg: 1.846 ± 0.443
6.769ThrSer: 6.769 ± 1.127
4.923ThrThr: 4.923 ± 1.716
4.923ThrVal: 4.923 ± 2.219
0.615ThrTrp: 0.615 ± 0.674
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.462ValAla: 2.462 ± 1.083
1.231ValCys: 1.231 ± 0.633
0.615ValAsp: 0.615 ± 0.674
6.769ValGlu: 6.769 ± 3.564
2.462ValPhe: 2.462 ± 1.327
2.462ValGly: 2.462 ± 1.659
2.462ValHis: 2.462 ± 0.613
3.692ValIle: 3.692 ± 2.571
3.692ValLys: 3.692 ± 1.344
6.769ValLeu: 6.769 ± 2.017
1.846ValMet: 1.846 ± 0.382
4.923ValAsn: 4.923 ± 1.49
2.462ValPro: 2.462 ± 1.659
2.462ValGln: 2.462 ± 1.299
3.077ValArg: 3.077 ± 0.92
4.308ValSer: 4.308 ± 0.726
4.923ValThr: 4.923 ± 2.384
4.923ValVal: 4.923 ± 1.584
0.0ValTrp: 0.0 ± 0.0
2.462ValTyr: 2.462 ± 0.613
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.615TrpAsp: 0.615 ± 0.674
1.846TrpGlu: 1.846 ± 0.959
0.0TrpPhe: 0.0 ± 0.0
0.615TrpGly: 0.615 ± 0.679
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.231TrpLys: 1.231 ± 0.633
0.0TrpLeu: 0.0 ± 0.0
0.615TrpMet: 0.615 ± 0.674
0.615TrpAsn: 0.615 ± 0.375
0.0TrpPro: 0.0 ± 0.0
1.231TrpGln: 1.231 ± 0.633
0.615TrpArg: 0.615 ± 0.674
1.231TrpSer: 1.231 ± 0.733
0.0TrpThr: 0.0 ± 0.0
0.615TrpVal: 0.615 ± 0.674
1.231TrpTrp: 1.231 ± 0.633
2.462TrpTyr: 2.462 ± 1.06
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.846TyrAla: 1.846 ± 1.203
0.0TyrCys: 0.0 ± 0.0
0.615TyrAsp: 0.615 ± 0.674
1.846TyrGlu: 1.846 ± 0.672
1.231TyrPhe: 1.231 ± 1.169
3.692TyrGly: 3.692 ± 1.008
2.462TyrHis: 2.462 ± 1.248
1.231TyrIle: 1.231 ± 0.583
0.615TyrLys: 0.615 ± 0.674
3.692TyrLeu: 3.692 ± 1.154
1.846TyrMet: 1.846 ± 1.126
2.462TyrAsn: 2.462 ± 1.023
3.077TyrPro: 3.077 ± 0.97
1.231TyrGln: 1.231 ± 0.583
3.692TyrArg: 3.692 ± 1.495
3.077TyrSer: 3.077 ± 0.6
1.231TyrThr: 1.231 ± 0.506
0.615TyrVal: 0.615 ± 0.674
0.615TyrTrp: 0.615 ± 0.375
1.231TyrTyr: 1.231 ± 1.348
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1626 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski