Amino acid dipepetide frequency for Pararobbsia alpina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.038AlaAla: 16.038 ± 0.125	1.277AlaCys: 1.277 ± 0.031	6.271AlaAsp: 6.271 ± 0.062	6.054AlaGlu: 6.054 ± 0.068	4.155AlaPhe: 4.155 ± 0.049	10.144AlaGly: 10.144 ± 0.093	2.79AlaHis: 2.79 ± 0.043	5.887AlaIle: 5.887 ± 0.056	3.653AlaLys: 3.653 ± 0.05	13.508AlaLeu: 13.508 ± 0.115	3.218AlaMet: 3.218 ± 0.04	3.273AlaAsn: 3.273 ± 0.048	5.541AlaPro: 5.541 ± 0.062	5.044AlaGln: 5.044 ± 0.059	8.429AlaArg: 8.429 ± 0.087	7.851AlaSer: 7.851 ± 0.087	6.204AlaThr: 6.204 ± 0.062	8.424AlaVal: 8.424 ± 0.067	1.541AlaTrp: 1.541 ± 0.034	2.605AlaTyr: 2.605 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	1.164CysAla: 1.164 ± 0.024	0.116CysCys: 0.116 ± 0.008	0.506CysAsp: 0.506 ± 0.016	0.514CysGlu: 0.514 ± 0.017	0.31CysPhe: 0.31 ± 0.012	0.96CysGly: 0.96 ± 0.028	0.273CysHis: 0.273 ± 0.014	0.418CysIle: 0.418 ± 0.016	0.216CysLys: 0.216 ± 0.01	0.854CysLeu: 0.854 ± 0.025	0.204CysMet: 0.204 ± 0.011	0.25CysAsn: 0.25 ± 0.011	0.441CysPro: 0.441 ± 0.019	0.234CysGln: 0.234 ± 0.011	0.644CysArg: 0.644 ± 0.02	0.511CysSer: 0.511 ± 0.018	0.495CysThr: 0.495 ± 0.018	0.787CysVal: 0.787 ± 0.019	0.14CysTrp: 0.14 ± 0.008	0.236CysTyr: 0.236 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.147AspAla: 7.147 ± 0.076	0.473AspCys: 0.473 ± 0.018	3.054AspAsp: 3.054 ± 0.044	3.429AspGlu: 3.429 ± 0.044	1.992AspPhe: 1.992 ± 0.034	4.56AspGly: 4.56 ± 0.054	1.224AspHis: 1.224 ± 0.028	2.625AspIle: 2.625 ± 0.039	1.635AspLys: 1.635 ± 0.029	5.29AspLeu: 5.29 ± 0.058	1.157AspMet: 1.157 ± 0.026	1.376AspAsn: 1.376 ± 0.032	3.081AspPro: 3.081 ± 0.043	1.573AspGln: 1.573 ± 0.031	3.632AspArg: 3.632 ± 0.05	2.776AspSer: 2.776 ± 0.042	2.825AspThr: 2.825 ± 0.047	4.231AspVal: 4.231 ± 0.05	0.915AspTrp: 0.915 ± 0.025	1.482AspTyr: 1.482 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	6.429GluAla: 6.429 ± 0.071	0.413GluCys: 0.413 ± 0.016	2.264GluAsp: 2.264 ± 0.036	2.332GluGlu: 2.332 ± 0.041	1.838GluPhe: 1.838 ± 0.031	3.503GluGly: 3.503 ± 0.047	1.543GluHis: 1.543 ± 0.034	2.933GluIle: 2.933 ± 0.043	1.716GluLys: 1.716 ± 0.033	5.613GluLeu: 5.613 ± 0.068	1.234GluMet: 1.234 ± 0.027	1.452GluAsn: 1.452 ± 0.032	2.538GluPro: 2.538 ± 0.04	2.502GluGln: 2.502 ± 0.039	4.745GluArg: 4.745 ± 0.065	2.781GluSer: 2.781 ± 0.041	2.844GluThr: 2.844 ± 0.041	3.759GluVal: 3.759 ± 0.052	0.727GluTrp: 0.727 ± 0.018	1.18GluTyr: 1.18 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.489PheAla: 4.489 ± 0.059	0.4PheCys: 0.4 ± 0.015	2.696PheAsp: 2.696 ± 0.044	2.187PheGlu: 2.187 ± 0.037	1.382PhePhe: 1.382 ± 0.038	3.663PheGly: 3.663 ± 0.056	0.797PheHis: 0.797 ± 0.021	1.645PheIle: 1.645 ± 0.031	1.118PheLys: 1.118 ± 0.026	3.014PheLeu: 3.014 ± 0.043	0.781PheMet: 0.781 ± 0.021	1.187PheAsn: 1.187 ± 0.028	1.554PhePro: 1.554 ± 0.029	1.017PheGln: 1.017 ± 0.023	2.007PheArg: 2.007 ± 0.035	2.367PheSer: 2.367 ± 0.036	1.895PheThr: 1.895 ± 0.034	3.015PheVal: 3.015 ± 0.045	0.532PheTrp: 0.532 ± 0.018	0.937PheTyr: 0.937 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	9.017GlyAla: 9.017 ± 0.081	0.835GlyCys: 0.835 ± 0.023	4.064GlyAsp: 4.064 ± 0.052	4.322GlyGlu: 4.322 ± 0.058	3.297GlyPhe: 3.297 ± 0.043	6.921GlyGly: 6.921 ± 0.103	1.943GlyHis: 1.943 ± 0.036	4.487GlyIle: 4.487 ± 0.06	3.217GlyLys: 3.217 ± 0.052	8.206GlyLeu: 8.206 ± 0.072	2.25GlyMet: 2.25 ± 0.036	2.407GlyAsn: 2.407 ± 0.045	3.026GlyPro: 3.026 ± 0.046	2.816GlyGln: 2.816 ± 0.046	5.34GlyArg: 5.34 ± 0.059	4.874GlySer: 4.874 ± 0.068	4.851GlyThr: 4.851 ± 0.069	6.392GlyVal: 6.392 ± 0.065	1.282GlyTrp: 1.282 ± 0.027	2.318GlyTyr: 2.318 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	3.062HisAla: 3.062 ± 0.048	0.27HisCys: 0.27 ± 0.012	1.388HisAsp: 1.388 ± 0.03	1.287HisGlu: 1.287 ± 0.025	0.988HisPhe: 0.988 ± 0.024	2.15HisGly: 2.15 ± 0.032	0.679HisHis: 0.679 ± 0.02	0.968HisIle: 0.968 ± 0.022	0.571HisLys: 0.571 ± 0.018	2.183HisLeu: 2.183 ± 0.037	0.529HisMet: 0.529 ± 0.016	0.512HisAsn: 0.512 ± 0.018	1.509HisPro: 1.509 ± 0.028	0.698HisGln: 0.698 ± 0.02	1.663HisArg: 1.663 ± 0.033	1.191HisSer: 1.191 ± 0.022	1.127HisThr: 1.127 ± 0.025	1.716HisVal: 1.716 ± 0.03	0.393HisTrp: 0.393 ± 0.015	0.642HisTyr: 0.642 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.065IleAla: 7.065 ± 0.062	0.467IleCys: 0.467 ± 0.017	3.606IleAsp: 3.606 ± 0.046	3.528IleGlu: 3.528 ± 0.049	1.474IlePhe: 1.474 ± 0.031	4.955IleGly: 4.955 ± 0.061	1.005IleHis: 1.005 ± 0.023	1.747IleIle: 1.747 ± 0.034	1.473IleLys: 1.473 ± 0.028	3.618IleLeu: 3.618 ± 0.044	0.814IleMet: 0.814 ± 0.022	1.474IleAsn: 1.474 ± 0.031	2.189IlePro: 2.189 ± 0.034	1.341IleGln: 1.341 ± 0.027	2.951IleArg: 2.951 ± 0.043	2.684IleSer: 2.684 ± 0.045	2.439IleThr: 2.439 ± 0.041	4.454IleVal: 4.454 ± 0.053	0.546IleTrp: 0.546 ± 0.02	1.084IleTyr: 1.084 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.595LysAla: 3.595 ± 0.05	0.185LysCys: 0.185 ± 0.01	1.465LysAsp: 1.465 ± 0.029	1.383LysGlu: 1.383 ± 0.032	0.872LysPhe: 0.872 ± 0.024	2.198LysGly: 2.198 ± 0.035	0.702LysHis: 0.702 ± 0.02	1.696LysIle: 1.696 ± 0.037	1.181LysLys: 1.181 ± 0.033	3.325LysLeu: 3.325 ± 0.049	0.815LysMet: 0.815 ± 0.022	0.87LysAsn: 0.87 ± 0.019	1.919LysPro: 1.919 ± 0.034	1.251LysGln: 1.251 ± 0.032	2.344LysArg: 2.344 ± 0.035	1.816LysSer: 1.816 ± 0.029	1.949LysThr: 1.949 ± 0.039	2.4LysVal: 2.4 ± 0.039	0.382LysTrp: 0.382 ± 0.014	0.717LysTyr: 0.717 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.396LeuAla: 13.396 ± 0.108	1.032LeuCys: 1.032 ± 0.021	6.082LeuAsp: 6.082 ± 0.062	5.237LeuGlu: 5.237 ± 0.067	3.649LeuPhe: 3.649 ± 0.043	8.104LeuGly: 8.104 ± 0.066	2.313LeuHis: 2.313 ± 0.036	4.865LeuIle: 4.865 ± 0.055	3.365LeuLys: 3.365 ± 0.049	10.192LeuLeu: 10.192 ± 0.105	2.282LeuMet: 2.282 ± 0.036	2.907LeuAsn: 2.907 ± 0.041	5.605LeuPro: 5.605 ± 0.07	3.3LeuGln: 3.3 ± 0.044	7.049LeuArg: 7.049 ± 0.074	6.816LeuSer: 6.816 ± 0.071	5.696LeuThr: 5.696 ± 0.073	7.478LeuVal: 7.478 ± 0.067	1.125LeuTrp: 1.125 ± 0.023	2.145LeuTyr: 2.145 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.474MetAla: 2.474 ± 0.036	0.183MetCys: 0.183 ± 0.01	0.979MetAsp: 0.979 ± 0.024	0.904MetGlu: 0.904 ± 0.022	0.791MetPhe: 0.791 ± 0.022	1.534MetGly: 1.534 ± 0.031	0.528MetHis: 0.528 ± 0.016	1.162MetIle: 1.162 ± 0.024	1.021MetLys: 1.021 ± 0.023	2.707MetLeu: 2.707 ± 0.039	0.624MetMet: 0.624 ± 0.019	0.954MetAsn: 0.954 ± 0.024	1.521MetPro: 1.521 ± 0.03	0.987MetGln: 0.987 ± 0.023	1.872MetArg: 1.872 ± 0.032	1.758MetSer: 1.758 ± 0.03	1.629MetThr: 1.629 ± 0.027	1.573MetVal: 1.573 ± 0.031	0.201MetTrp: 0.201 ± 0.011	0.394MetTyr: 0.394 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.48AsnAla: 3.48 ± 0.047	0.264AsnCys: 0.264 ± 0.01	1.555AsnAsp: 1.555 ± 0.031	1.396AsnGlu: 1.396 ± 0.029	1.049AsnPhe: 1.049 ± 0.026	2.622AsnGly: 2.622 ± 0.043	0.575AsnHis: 0.575 ± 0.017	1.261AsnIle: 1.261 ± 0.026	0.729AsnLys: 0.729 ± 0.02	2.847AsnLeu: 2.847 ± 0.039	0.585AsnMet: 0.585 ± 0.018	0.807AsnAsn: 0.807 ± 0.027	1.826AsnPro: 1.826 ± 0.037	0.949AsnGln: 0.949 ± 0.022	1.865AsnArg: 1.865 ± 0.03	1.478AsnSer: 1.478 ± 0.032	1.556AsnThr: 1.556 ± 0.034	2.202AsnVal: 2.202 ± 0.036	0.436AsnTrp: 0.436 ± 0.017	0.754AsnTyr: 0.754 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	6.298ProAla: 6.298 ± 0.064	0.377ProCys: 0.377 ± 0.016	3.224ProAsp: 3.224 ± 0.047	2.948ProGlu: 2.948 ± 0.049	1.969ProPhe: 1.969 ± 0.035	4.171ProGly: 4.171 ± 0.057	1.205ProHis: 1.205 ± 0.025	2.128ProIle: 2.128 ± 0.033	1.422ProLys: 1.422 ± 0.029	5.088ProLeu: 5.088 ± 0.059	1.147ProMet: 1.147 ± 0.025	1.508ProAsn: 1.508 ± 0.029	2.586ProPro: 2.586 ± 0.048	1.742ProGln: 1.742 ± 0.029	2.946ProArg: 2.946 ± 0.044	3.17ProSer: 3.17 ± 0.047	2.744ProThr: 2.744 ± 0.041	4.335ProVal: 4.335 ± 0.054	0.649ProTrp: 0.649 ± 0.019	1.192ProTyr: 1.192 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.462GlnAla: 4.462 ± 0.055	0.283GlnCys: 0.283 ± 0.013	1.405GlnAsp: 1.405 ± 0.029	1.386GlnGlu: 1.386 ± 0.027	1.255GlnPhe: 1.255 ± 0.027	2.497GlnGly: 2.497 ± 0.038	0.915GlnHis: 0.915 ± 0.026	2.02GlnIle: 2.02 ± 0.041	1.053GlnLys: 1.053 ± 0.027	3.691GlnLeu: 3.691 ± 0.052	1.02GlnMet: 1.02 ± 0.025	0.99GlnAsn: 0.99 ± 0.024	1.875GlnPro: 1.875 ± 0.034	1.807GlnGln: 1.807 ± 0.052	2.922GlnArg: 2.922 ± 0.052	2.142GlnSer: 2.142 ± 0.037	2.078GlnThr: 2.078 ± 0.037	2.662GlnVal: 2.662 ± 0.046	0.568GlnTrp: 0.568 ± 0.017	0.908GlnTyr: 0.908 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	7.904ArgAla: 7.904 ± 0.068	0.635ArgCys: 0.635 ± 0.022	3.83ArgAsp: 3.83 ± 0.044	4.162ArgGlu: 4.162 ± 0.052	2.926ArgPhe: 2.926 ± 0.041	4.68ArgGly: 4.68 ± 0.06	1.798ArgHis: 1.798 ± 0.031	3.665ArgIle: 3.665 ± 0.048	2.217ArgLys: 2.217 ± 0.037	7.332ArgLeu: 7.332 ± 0.076	1.801ArgMet: 1.801 ± 0.029	1.849ArgAsn: 1.849 ± 0.033	3.197ArgPro: 3.197 ± 0.043	2.624ArgGln: 2.624 ± 0.039	5.405ArgArg: 5.405 ± 0.059	3.82ArgSer: 3.82 ± 0.046	3.57ArgThr: 3.57 ± 0.041	5.212ArgVal: 5.212 ± 0.055	1.082ArgTrp: 1.082 ± 0.026	1.877ArgTyr: 1.877 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	7.029SerAla: 7.029 ± 0.075	0.491SerCys: 0.491 ± 0.017	3.045SerAsp: 3.045 ± 0.045	2.882SerGlu: 2.882 ± 0.045	2.299SerPhe: 2.299 ± 0.034	5.658SerGly: 5.658 ± 0.067	1.366SerHis: 1.366 ± 0.032	3.101SerIle: 3.101 ± 0.047	1.723SerLys: 1.723 ± 0.031	6.278SerLeu: 6.278 ± 0.065	1.554SerMet: 1.554 ± 0.028	1.777SerAsn: 1.777 ± 0.035	3.098SerPro: 3.098 ± 0.044	1.983SerGln: 1.983 ± 0.035	3.975SerArg: 3.975 ± 0.052	4.005SerSer: 4.005 ± 0.06	3.474SerThr: 3.474 ± 0.057	4.493SerVal: 4.493 ± 0.054	0.756SerTrp: 0.756 ± 0.02	1.352SerTyr: 1.352 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	6.07ThrAla: 6.07 ± 0.073	0.406ThrCys: 0.406 ± 0.015	2.713ThrAsp: 2.713 ± 0.039	2.418ThrGlu: 2.418 ± 0.036	1.958ThrPhe: 1.958 ± 0.034	4.894ThrGly: 4.894 ± 0.057	1.302ThrHis: 1.302 ± 0.027	2.841ThrIle: 2.841 ± 0.042	1.278ThrLys: 1.278 ± 0.027	6.484ThrLeu: 6.484 ± 0.071	1.194ThrMet: 1.194 ± 0.027	1.366ThrAsn: 1.366 ± 0.031	3.468ThrPro: 3.468 ± 0.041	2.024ThrGln: 2.024 ± 0.044	3.632ThrArg: 3.632 ± 0.044	3.259ThrSer: 3.259 ± 0.048	3.112ThrThr: 3.112 ± 0.068	4.507ThrVal: 4.507 ± 0.056	0.632ThrTrp: 0.632 ± 0.019	1.249ThrTyr: 1.249 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	9.048ValAla: 9.048 ± 0.068	0.762ValCys: 0.762 ± 0.023	4.392ValAsp: 4.392 ± 0.044	4.183ValGlu: 4.183 ± 0.051	2.881ValPhe: 2.881 ± 0.04	5.739ValGly: 5.739 ± 0.061	1.692ValHis: 1.692 ± 0.031	3.887ValIle: 3.887 ± 0.055	2.417ValLys: 2.417 ± 0.043	8.022ValLeu: 8.022 ± 0.072	1.792ValMet: 1.792 ± 0.034	2.184ValAsn: 2.184 ± 0.039	3.971ValPro: 3.971 ± 0.051	2.488ValGln: 2.488 ± 0.036	5.143ValArg: 5.143 ± 0.05	4.864ValSer: 4.864 ± 0.056	4.411ValThr: 4.411 ± 0.049	6.261ValVal: 6.261 ± 0.073	0.924ValTrp: 0.924 ± 0.019	1.6ValTyr: 1.6 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.108TrpAla: 1.108 ± 0.021	0.148TrpCys: 0.148 ± 0.009	0.618TrpAsp: 0.618 ± 0.02	0.507TrpGlu: 0.507 ± 0.016	0.554TrpPhe: 0.554 ± 0.018	0.827TrpGly: 0.827 ± 0.021	0.388TrpHis: 0.388 ± 0.013	0.713TrpIle: 0.713 ± 0.019	0.419TrpLys: 0.419 ± 0.014	1.856TrpLeu: 1.856 ± 0.036	0.365TrpMet: 0.365 ± 0.014	0.463TrpAsn: 0.463 ± 0.018	0.648TrpPro: 0.648 ± 0.02	0.644TrpGln: 0.644 ± 0.022	1.147TrpArg: 1.147 ± 0.027	0.826TrpSer: 0.826 ± 0.019	0.716TrpThr: 0.716 ± 0.021	0.958TrpVal: 0.958 ± 0.024	0.222TrpTrp: 0.222 ± 0.01	0.317TrpTyr: 0.317 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.632TyrAla: 2.632 ± 0.042	0.257TyrCys: 0.257 ± 0.013	1.321TyrAsp: 1.321 ± 0.026	1.29TyrGlu: 1.29 ± 0.027	1.041TyrPhe: 1.041 ± 0.023	2.086TyrGly: 2.086 ± 0.037	0.49TyrHis: 0.49 ± 0.019	0.865TyrIle: 0.865 ± 0.022	0.638TyrLys: 0.638 ± 0.019	2.532TyrLeu: 2.532 ± 0.044	0.432TyrMet: 0.432 ± 0.016	0.631TyrAsn: 0.631 ± 0.019	1.254TyrPro: 1.254 ± 0.025	0.913TyrGln: 0.913 ± 0.022	1.877TyrArg: 1.877 ± 0.032	1.35TyrSer: 1.35 ± 0.031	1.187TyrThr: 1.187 ± 0.026	1.801TyrVal: 1.801 ± 0.031	0.392TyrTrp: 0.392 ± 0.014	0.663TyrTyr: 0.663 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6080 proteins (1865431 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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