Amino acid dipepetide frequency for Wuhan sharpbelly bornavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.612AlaAla: 5.612 ± 1.474
2.311AlaCys: 2.311 ± 0.925
3.632AlaAsp: 3.632 ± 0.906
4.952AlaGlu: 4.952 ± 0.899
1.321AlaPhe: 1.321 ± 0.755
3.962AlaGly: 3.962 ± 1.752
1.321AlaHis: 1.321 ± 0.364
3.632AlaIle: 3.632 ± 1.557
2.641AlaLys: 2.641 ± 0.661
8.914AlaLeu: 8.914 ± 1.715
0.99AlaMet: 0.99 ± 0.998
2.641AlaAsn: 2.641 ± 1.443
2.971AlaPro: 2.971 ± 1.414
1.651AlaGln: 1.651 ± 0.704
0.99AlaArg: 0.99 ± 0.593
4.292AlaSer: 4.292 ± 1.779
3.632AlaThr: 3.632 ± 1.279
5.612AlaVal: 5.612 ± 2.392
0.99AlaTrp: 0.99 ± 0.857
2.641AlaTyr: 2.641 ± 0.536
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.66CysCys: 0.66 ± 0.378
1.651CysAsp: 1.651 ± 1.445
0.33CysGlu: 0.33 ± 0.189
1.321CysPhe: 1.321 ± 0.364
1.651CysGly: 1.651 ± 0.726
0.99CysHis: 0.99 ± 0.567
1.321CysIle: 1.321 ± 0.801
0.99CysLys: 0.99 ± 0.374
3.962CysLeu: 3.962 ± 1.512
0.99CysMet: 0.99 ± 0.374
0.66CysAsn: 0.66 ± 0.378
0.99CysPro: 0.99 ± 0.567
0.33CysGln: 0.33 ± 0.189
0.0CysArg: 0.0 ± 0.0
0.99CysSer: 0.99 ± 0.815
2.311CysThr: 2.311 ± 1.552
0.99CysVal: 0.99 ± 0.567
0.66CysTrp: 0.66 ± 0.378
0.66CysTyr: 0.66 ± 0.918
0.0CysXaa: 0.0 ± 0.0
Asp
2.641AspAla: 2.641 ± 2.389
0.99AspCys: 0.99 ± 0.815
1.321AspAsp: 1.321 ± 0.988
3.632AspGlu: 3.632 ± 1.357
2.641AspPhe: 2.641 ± 1.735
0.66AspGly: 0.66 ± 0.378
0.99AspHis: 0.99 ± 0.567
3.301AspIle: 3.301 ± 1.432
2.971AspLys: 2.971 ± 1.109
3.962AspLeu: 3.962 ± 1.288
1.651AspMet: 1.651 ± 0.726
0.66AspAsn: 0.66 ± 0.378
3.632AspPro: 3.632 ± 1.462
3.301AspGln: 3.301 ± 0.898
1.981AspArg: 1.981 ± 0.687
4.292AspSer: 4.292 ± 1.528
3.962AspThr: 3.962 ± 1.259
1.321AspVal: 1.321 ± 0.713
0.66AspTrp: 0.66 ± 0.378
2.971AspTyr: 2.971 ± 0.667
0.0AspXaa: 0.0 ± 0.0
Glu
4.622GluAla: 4.622 ± 2.716
0.66GluCys: 0.66 ± 0.374
1.981GluAsp: 1.981 ± 0.973
7.263GluGlu: 7.263 ± 3.437
0.66GluPhe: 0.66 ± 0.774
2.641GluGly: 2.641 ± 0.763
0.99GluHis: 0.99 ± 0.853
3.962GluIle: 3.962 ± 0.746
2.971GluLys: 2.971 ± 1.099
4.292GluLeu: 4.292 ± 0.942
0.66GluMet: 0.66 ± 0.385
1.321GluAsn: 1.321 ± 0.364
2.641GluPro: 2.641 ± 1.617
3.962GluGln: 3.962 ± 0.632
1.981GluArg: 1.981 ± 1.154
4.952GluSer: 4.952 ± 1.013
2.311GluThr: 2.311 ± 0.668
2.971GluVal: 2.971 ± 1.281
0.33GluTrp: 0.33 ± 0.854
2.641GluTyr: 2.641 ± 1.147
0.0GluXaa: 0.0 ± 0.0
Phe
0.99PheAla: 0.99 ± 0.734
0.66PheCys: 0.66 ± 0.374
1.651PheAsp: 1.651 ± 0.723
1.321PheGlu: 1.321 ± 0.802
1.981PhePhe: 1.981 ± 1.133
1.321PheGly: 1.321 ± 0.516
1.321PheHis: 1.321 ± 1.593
1.981PheIle: 1.981 ± 0.748
2.311PheLys: 2.311 ± 1.15
1.651PheLeu: 1.651 ± 0.596
0.66PheMet: 0.66 ± 1.184
0.99PheAsn: 0.99 ± 0.734
1.651PhePro: 1.651 ± 1.037
2.641PheGln: 2.641 ± 1.076
1.651PheArg: 1.651 ± 0.643
3.301PheSer: 3.301 ± 1.09
3.301PheThr: 3.301 ± 1.889
1.981PheVal: 1.981 ± 0.493
0.0PheTrp: 0.0 ± 0.0
0.99PheTyr: 0.99 ± 0.374
0.0PheXaa: 0.0 ± 0.0
Gly
3.962GlyAla: 3.962 ± 1.128
2.641GlyCys: 2.641 ± 0.799
3.301GlyAsp: 3.301 ± 1.003
3.301GlyGlu: 3.301 ± 1.093
0.33GlyPhe: 0.33 ± 0.189
5.282GlyGly: 5.282 ± 2.814
0.33GlyHis: 0.33 ± 0.406
2.641GlyIle: 2.641 ± 1.136
2.641GlyLys: 2.641 ± 1.857
6.273GlyLeu: 6.273 ± 2.189
1.651GlyMet: 1.651 ± 0.39
1.321GlyAsn: 1.321 ± 0.496
2.311GlyPro: 2.311 ± 1.434
3.632GlyGln: 3.632 ± 1.452
3.301GlyArg: 3.301 ± 1.125
6.603GlySer: 6.603 ± 1.485
3.632GlyThr: 3.632 ± 1.016
3.962GlyVal: 3.962 ± 0.891
0.0GlyTrp: 0.0 ± 0.0
1.981GlyTyr: 1.981 ± 0.625
0.0GlyXaa: 0.0 ± 0.0
His
1.981HisAla: 1.981 ± 0.625
0.0HisCys: 0.0 ± 0.0
0.99HisAsp: 0.99 ± 0.45
0.33HisGlu: 0.33 ± 0.459
1.321HisPhe: 1.321 ± 0.747
1.981HisGly: 1.981 ± 0.756
0.66HisHis: 0.66 ± 0.378
2.641HisIle: 2.641 ± 0.487
0.66HisLys: 0.66 ± 0.74
2.311HisLeu: 2.311 ± 0.668
0.33HisMet: 0.33 ± 0.189
1.981HisAsn: 1.981 ± 0.879
1.321HisPro: 1.321 ± 0.801
1.651HisGln: 1.651 ± 0.749
1.651HisArg: 1.651 ± 0.973
2.311HisSer: 2.311 ± 1.063
1.981HisThr: 1.981 ± 0.859
3.301HisVal: 3.301 ± 1.494
0.66HisTrp: 0.66 ± 0.378
0.99HisTyr: 0.99 ± 0.815
0.0HisXaa: 0.0 ± 0.0
Ile
3.301IleAla: 3.301 ± 1.477
0.99IleCys: 0.99 ± 0.815
2.311IleAsp: 2.311 ± 0.783
3.301IleGlu: 3.301 ± 1.177
1.321IlePhe: 1.321 ± 0.755
2.971IleGly: 2.971 ± 1.047
1.321IleHis: 1.321 ± 0.588
4.292IleIle: 4.292 ± 1.419
3.962IleLys: 3.962 ± 1.835
5.612IleLeu: 5.612 ± 1.07
1.321IleMet: 1.321 ± 0.755
2.311IleAsn: 2.311 ± 0.794
2.311IlePro: 2.311 ± 0.666
1.651IleGln: 1.651 ± 0.816
2.641IleArg: 2.641 ± 1.006
5.282IleSer: 5.282 ± 1.282
4.952IleThr: 4.952 ± 1.107
4.622IleVal: 4.622 ± 0.557
0.33IleTrp: 0.33 ± 0.459
0.99IleTyr: 0.99 ± 0.815
0.0IleXaa: 0.0 ± 0.0
Lys
3.962LysAla: 3.962 ± 1.147
0.66LysCys: 0.66 ± 0.385
3.301LysAsp: 3.301 ± 1.083
3.632LysGlu: 3.632 ± 0.909
2.971LysPhe: 2.971 ± 0.621
3.301LysGly: 3.301 ± 1.167
1.651LysHis: 1.651 ± 0.596
1.981LysIle: 1.981 ± 1.241
1.981LysLys: 1.981 ± 0.755
5.943LysLeu: 5.943 ± 1.276
1.651LysMet: 1.651 ± 0.923
0.33LysAsn: 0.33 ± 0.189
1.651LysPro: 1.651 ± 0.738
1.981LysGln: 1.981 ± 0.985
3.632LysArg: 3.632 ± 1.51
4.622LysSer: 4.622 ± 1.6
2.641LysThr: 2.641 ± 1.052
3.301LysVal: 3.301 ± 1.01
0.0LysTrp: 0.0 ± 0.0
3.962LysTyr: 3.962 ± 1.263
0.0LysXaa: 0.0 ± 0.0
Leu
4.952LeuAla: 4.952 ± 1.444
1.651LeuCys: 1.651 ± 0.596
6.933LeuAsp: 6.933 ± 2.478
5.282LeuGlu: 5.282 ± 1.301
0.99LeuPhe: 0.99 ± 0.374
4.292LeuGly: 4.292 ± 1.555
3.301LeuHis: 3.301 ± 0.68
5.943LeuIle: 5.943 ± 1.33
7.593LeuLys: 7.593 ± 0.929
12.545LeuLeu: 12.545 ± 1.359
1.981LeuMet: 1.981 ± 0.875
1.651LeuAsn: 1.651 ± 0.619
7.923LeuPro: 7.923 ± 0.47
2.971LeuGln: 2.971 ± 1.898
6.603LeuArg: 6.603 ± 1.229
11.885LeuSer: 11.885 ± 3.703
6.273LeuThr: 6.273 ± 1.47
7.593LeuVal: 7.593 ± 2.096
0.99LeuTrp: 0.99 ± 0.567
4.292LeuTyr: 4.292 ± 0.812
0.0LeuXaa: 0.0 ± 0.0
Met
1.981MetAla: 1.981 ± 0.947
0.0MetCys: 0.0 ± 0.0
0.99MetAsp: 0.99 ± 0.45
1.321MetGlu: 1.321 ± 0.755
1.981MetPhe: 1.981 ± 0.493
0.66MetGly: 0.66 ± 0.378
0.33MetHis: 0.33 ± 0.854
1.321MetIle: 1.321 ± 0.77
1.981MetLys: 1.981 ± 2.165
1.981MetLeu: 1.981 ± 1.133
0.66MetMet: 0.66 ± 0.595
0.99MetAsn: 0.99 ± 0.567
1.321MetPro: 1.321 ± 0.46
0.66MetGln: 0.66 ± 0.374
1.651MetArg: 1.651 ± 0.726
1.651MetSer: 1.651 ± 1.174
2.311MetThr: 2.311 ± 0.637
0.66MetVal: 0.66 ± 0.595
0.33MetTrp: 0.33 ± 0.189
1.321MetTyr: 1.321 ± 1.082
0.0MetXaa: 0.0 ± 0.0
Asn
3.962AsnAla: 3.962 ± 0.915
0.33AsnCys: 0.33 ± 0.189
0.66AsnAsp: 0.66 ± 0.918
2.311AsnGlu: 2.311 ± 1.014
0.66AsnPhe: 0.66 ± 0.385
0.99AsnGly: 0.99 ± 0.815
1.321AsnHis: 1.321 ± 0.46
2.311AsnIle: 2.311 ± 0.925
1.321AsnLys: 1.321 ± 1.307
2.641AsnLeu: 2.641 ± 0.928
0.66AsnMet: 0.66 ± 0.378
0.66AsnAsn: 0.66 ± 1.309
1.321AsnPro: 1.321 ± 0.649
1.651AsnGln: 1.651 ± 1.382
0.99AsnArg: 0.99 ± 1.217
0.66AsnSer: 0.66 ± 0.555
2.311AsnThr: 2.311 ± 1.322
1.651AsnVal: 1.651 ± 0.643
0.0AsnTrp: 0.0 ± 0.0
0.99AsnTyr: 0.99 ± 0.567
0.0AsnXaa: 0.0 ± 0.0
Pro
3.301ProAla: 3.301 ± 0.901
1.651ProCys: 1.651 ± 0.596
1.981ProAsp: 1.981 ± 0.451
2.641ProGlu: 2.641 ± 1.04
1.651ProPhe: 1.651 ± 0.738
4.952ProGly: 4.952 ± 2.12
2.311ProHis: 2.311 ± 1.883
2.971ProIle: 2.971 ± 0.866
2.311ProLys: 2.311 ± 0.753
6.603ProLeu: 6.603 ± 1.239
0.66ProMet: 0.66 ± 0.816
1.651ProAsn: 1.651 ± 0.816
5.612ProPro: 5.612 ± 2.677
0.99ProGln: 0.99 ± 0.68
2.641ProArg: 2.641 ± 0.798
4.622ProSer: 4.622 ± 2.216
3.962ProThr: 3.962 ± 1.763
4.622ProVal: 4.622 ± 1.517
0.66ProTrp: 0.66 ± 0.374
0.99ProTyr: 0.99 ± 0.374
0.0ProXaa: 0.0 ± 0.0
Gln
2.971GlnAla: 2.971 ± 0.731
1.321GlnCys: 1.321 ± 0.755
2.971GlnAsp: 2.971 ± 1.737
2.971GlnGlu: 2.971 ± 1.518
2.641GlnPhe: 2.641 ± 1.485
4.622GlnGly: 4.622 ± 1.49
0.66GlnHis: 0.66 ± 0.774
1.981GlnIle: 1.981 ± 1.154
0.99GlnLys: 0.99 ± 0.567
2.971GlnLeu: 2.971 ± 0.933
0.99GlnMet: 0.99 ± 1.237
0.66GlnAsn: 0.66 ± 0.555
1.651GlnPro: 1.651 ± 0.494
1.651GlnGln: 1.651 ± 0.674
1.981GlnArg: 1.981 ± 0.748
2.971GlnSer: 2.971 ± 1.036
2.311GlnThr: 2.311 ± 1.229
3.962GlnVal: 3.962 ± 0.865
0.0GlnTrp: 0.0 ± 0.0
1.981GlnTyr: 1.981 ± 1.906
0.0GlnXaa: 0.0 ± 0.0
Arg
1.321ArgAla: 1.321 ± 0.516
0.99ArgCys: 0.99 ± 0.821
2.641ArgAsp: 2.641 ± 1.338
1.321ArgGlu: 1.321 ± 0.606
1.651ArgPhe: 1.651 ± 0.726
2.971ArgGly: 2.971 ± 0.933
1.981ArgHis: 1.981 ± 0.755
1.981ArgIle: 1.981 ± 0.894
1.651ArgLys: 1.651 ± 0.555
8.584ArgLeu: 8.584 ± 2.281
2.641ArgMet: 2.641 ± 1.122
2.311ArgAsn: 2.311 ± 1.01
2.641ArgPro: 2.641 ± 0.536
1.321ArgGln: 1.321 ± 0.491
3.962ArgArg: 3.962 ± 0.49
4.952ArgSer: 4.952 ± 1.166
3.301ArgThr: 3.301 ± 1.177
3.962ArgVal: 3.962 ± 1.435
0.99ArgTrp: 0.99 ± 0.567
0.66ArgTyr: 0.66 ± 0.374
0.0ArgXaa: 0.0 ± 0.0
Ser
3.632SerAla: 3.632 ± 1.181
2.641SerCys: 2.641 ± 1.101
4.622SerAsp: 4.622 ± 0.779
1.981SerGlu: 1.981 ± 1.154
2.641SerPhe: 2.641 ± 0.799
5.943SerGly: 5.943 ± 2.487
3.632SerHis: 3.632 ± 1.308
5.282SerIle: 5.282 ± 1.638
4.292SerLys: 4.292 ± 0.843
9.244SerLeu: 9.244 ± 1.551
2.641SerMet: 2.641 ± 0.707
2.311SerAsn: 2.311 ± 0.925
5.282SerPro: 5.282 ± 0.789
3.301SerGln: 3.301 ± 0.857
5.612SerArg: 5.612 ± 2.347
9.244SerSer: 9.244 ± 1.815
6.603SerThr: 6.603 ± 2.382
5.282SerVal: 5.282 ± 1.271
0.99SerTrp: 0.99 ± 0.815
0.99SerTyr: 0.99 ± 0.374
0.0SerXaa: 0.0 ± 0.0
Thr
4.622ThrAla: 4.622 ± 0.724
1.321ThrCys: 1.321 ± 0.801
2.971ThrAsp: 2.971 ± 0.933
3.301ThrGlu: 3.301 ± 0.726
2.971ThrPhe: 2.971 ± 0.566
3.301ThrGly: 3.301 ± 1.463
3.301ThrHis: 3.301 ± 0.746
3.632ThrIle: 3.632 ± 1.801
4.622ThrLys: 4.622 ± 1.308
6.603ThrLeu: 6.603 ± 1.878
1.321ThrMet: 1.321 ± 0.755
1.321ThrAsn: 1.321 ± 0.46
3.632ThrPro: 3.632 ± 0.785
1.651ThrGln: 1.651 ± 0.813
5.282ThrArg: 5.282 ± 1.025
5.943ThrSer: 5.943 ± 1.809
7.593ThrThr: 7.593 ± 4.625
5.943ThrVal: 5.943 ± 1.317
1.321ThrTrp: 1.321 ± 0.755
1.321ThrTyr: 1.321 ± 0.713
0.0ThrXaa: 0.0 ± 0.0
Val
7.923ValAla: 7.923 ± 1.917
0.33ValCys: 0.33 ± 0.459
2.971ValAsp: 2.971 ± 1.219
2.311ValGlu: 2.311 ± 1.063
1.981ValPhe: 1.981 ± 1.12
5.282ValGly: 5.282 ± 1.019
1.321ValHis: 1.321 ± 0.755
2.641ValIle: 2.641 ± 0.928
5.612ValLys: 5.612 ± 1.618
6.933ValLeu: 6.933 ± 0.832
1.321ValMet: 1.321 ± 0.364
2.311ValAsn: 2.311 ± 1.187
3.632ValPro: 3.632 ± 1.359
4.622ValGln: 4.622 ± 0.969
3.632ValArg: 3.632 ± 0.857
3.962ValSer: 3.962 ± 0.855
5.282ValThr: 5.282 ± 1.792
4.952ValVal: 4.952 ± 1.497
0.66ValTrp: 0.66 ± 0.955
2.971ValTyr: 2.971 ± 0.967
0.0ValXaa: 0.0 ± 0.0
Trp
1.321TrpAla: 1.321 ± 0.755
0.33TrpCys: 0.33 ± 0.189
0.0TrpAsp: 0.0 ± 0.0
0.66TrpGlu: 0.66 ± 0.774
0.0TrpPhe: 0.0 ± 0.0
0.99TrpGly: 0.99 ± 0.815
0.33TrpHis: 0.33 ± 0.406
0.33TrpIle: 0.33 ± 0.189
0.66TrpLys: 0.66 ± 0.374
0.66TrpLeu: 0.66 ± 0.385
0.99TrpMet: 0.99 ± 0.734
0.0TrpAsn: 0.0 ± 0.0
0.99TrpPro: 0.99 ± 0.567
0.0TrpGln: 0.0 ± 0.0
0.33TrpArg: 0.33 ± 0.459
0.33TrpSer: 0.33 ± 0.459
1.321TrpThr: 1.321 ± 0.747
0.66TrpVal: 0.66 ± 0.378
0.66TrpTrp: 0.66 ± 0.918
0.33TrpTyr: 0.33 ± 0.189
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.651TyrAla: 1.651 ± 0.726
1.321TyrCys: 1.321 ± 0.801
0.66TyrAsp: 0.66 ± 0.374
1.651TyrGlu: 1.651 ± 0.643
1.321TyrPhe: 1.321 ± 0.46
1.321TyrGly: 1.321 ± 0.755
0.99TyrHis: 0.99 ± 0.821
1.651TyrIle: 1.651 ± 0.491
0.99TyrLys: 0.99 ± 0.815
3.962TyrLeu: 3.962 ± 1.288
0.33TyrMet: 0.33 ± 0.189
1.321TyrAsn: 1.321 ± 0.649
3.632TyrPro: 3.632 ± 1.508
2.311TyrGln: 2.311 ± 0.637
1.321TyrArg: 1.321 ± 0.743
3.301TyrSer: 3.301 ± 0.531
1.981TyrThr: 1.981 ± 1.264
3.301TyrVal: 3.301 ± 1.912
0.66TyrTrp: 0.66 ± 0.374
1.651TyrTyr: 1.651 ± 0.797
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3030 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski