Amino acid dipepetide frequency for Albimonas donghaensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	26.081AlaAla: 26.081 ± 0.267	1.258AlaCys: 1.258 ± 0.034	8.173AlaAsp: 8.173 ± 0.095	10.512AlaGlu: 10.512 ± 0.113	4.709AlaPhe: 4.709 ± 0.063	14.585AlaGly: 14.585 ± 0.162	2.501AlaHis: 2.501 ± 0.046	5.6AlaIle: 5.6 ± 0.07	3.029AlaLys: 3.029 ± 0.054	17.156AlaLeu: 17.156 ± 0.17	4.358AlaMet: 4.358 ± 0.068	2.305AlaAsn: 2.305 ± 0.044	10.275AlaPro: 10.275 ± 0.13	3.997AlaGln: 3.997 ± 0.062	12.786AlaArg: 12.786 ± 0.146	6.644AlaSer: 6.644 ± 0.076	6.102AlaThr: 6.102 ± 0.089	9.316AlaVal: 9.316 ± 0.095	2.163AlaTrp: 2.163 ± 0.04	2.397AlaTyr: 2.397 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.302CysAla: 1.302 ± 0.031	0.098CysCys: 0.098 ± 0.009	0.54CysAsp: 0.54 ± 0.02	0.423CysGlu: 0.423 ± 0.018	0.32CysPhe: 0.32 ± 0.015	0.959CysGly: 0.959 ± 0.028	0.199CysHis: 0.199 ± 0.013	0.307CysIle: 0.307 ± 0.016	0.152CysLys: 0.152 ± 0.01	0.798CysLeu: 0.798 ± 0.025	0.159CysMet: 0.159 ± 0.012	0.152CysAsn: 0.152 ± 0.011	0.449CysPro: 0.449 ± 0.017	0.161CysGln: 0.161 ± 0.01	0.545CysArg: 0.545 ± 0.019	0.355CysSer: 0.355 ± 0.015	0.351CysThr: 0.351 ± 0.017	0.625CysVal: 0.625 ± 0.021	0.116CysTrp: 0.116 ± 0.01	0.16CysTyr: 0.16 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	9.406AspAla: 9.406 ± 0.112	0.468AspCys: 0.468 ± 0.02	3.344AspAsp: 3.344 ± 0.088	3.191AspGlu: 3.191 ± 0.052	2.295AspPhe: 2.295 ± 0.045	6.132AspGly: 6.132 ± 0.146	1.2AspHis: 1.2 ± 0.033	2.331AspIle: 2.331 ± 0.047	1.153AspLys: 1.153 ± 0.031	6.33AspLeu: 6.33 ± 0.083	1.522AspMet: 1.522 ± 0.036	0.945AspAsn: 0.945 ± 0.035	4.623AspPro: 4.623 ± 0.072	1.4AspGln: 1.4 ± 0.038	4.868AspArg: 4.868 ± 0.072	1.817AspSer: 1.817 ± 0.048	2.084AspThr: 2.084 ± 0.047	3.968AspVal: 3.968 ± 0.061	1.187AspTrp: 1.187 ± 0.035	1.339AspTyr: 1.339 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	10.825GluAla: 10.825 ± 0.118	0.305GluCys: 0.305 ± 0.016	3.44GluAsp: 3.44 ± 0.06	3.177GluGlu: 3.177 ± 0.065	1.683GluPhe: 1.683 ± 0.029	5.737GluGly: 5.737 ± 0.073	0.957GluHis: 0.957 ± 0.027	3.54GluIle: 3.54 ± 0.052	1.609GluLys: 1.609 ± 0.037	4.905GluLeu: 4.905 ± 0.063	1.585GluMet: 1.585 ± 0.033	1.258GluAsn: 1.258 ± 0.031	2.953GluPro: 2.953 ± 0.054	1.446GluGln: 1.446 ± 0.037	4.527GluArg: 4.527 ± 0.073	2.176GluSer: 2.176 ± 0.041	4.383GluThr: 4.383 ± 0.058	3.974GluVal: 3.974 ± 0.065	0.692GluTrp: 0.692 ± 0.023	0.822GluTyr: 0.822 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	5.162PheAla: 5.162 ± 0.076	0.377PheCys: 0.377 ± 0.017	2.631PheAsp: 2.631 ± 0.057	2.187PheGlu: 2.187 ± 0.042	1.189PhePhe: 1.189 ± 0.032	3.791PheGly: 3.791 ± 0.054	0.702PheHis: 0.702 ± 0.022	1.175PheIle: 1.175 ± 0.029	0.706PheLys: 0.706 ± 0.025	3.133PheLeu: 3.133 ± 0.053	0.742PheMet: 0.742 ± 0.023	0.785PheAsn: 0.785 ± 0.024	1.567PhePro: 1.567 ± 0.034	0.836PheGln: 0.836 ± 0.023	2.336PheArg: 2.336 ± 0.044	1.894PheSer: 1.894 ± 0.037	1.531PheThr: 1.531 ± 0.034	2.479PheVal: 2.479 ± 0.048	0.518PheTrp: 0.518 ± 0.02	0.68PheTyr: 0.68 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	14.65GlyAla: 14.65 ± 0.149	0.844GlyCys: 0.844 ± 0.028	5.424GlyAsp: 5.424 ± 0.122	5.653GlyGlu: 5.653 ± 0.074	3.797GlyPhe: 3.797 ± 0.055	10.309GlyGly: 10.309 ± 0.274	1.71GlyHis: 1.71 ± 0.041	3.646GlyIle: 3.646 ± 0.06	2.46GlyLys: 2.46 ± 0.046	10.477GlyLeu: 10.477 ± 0.112	2.835GlyMet: 2.835 ± 0.052	1.456GlyAsn: 1.456 ± 0.038	5.184GlyPro: 5.184 ± 0.071	2.404GlyGln: 2.404 ± 0.058	7.755GlyArg: 7.755 ± 0.092	4.123GlySer: 4.123 ± 0.081	3.854GlyThr: 3.854 ± 0.062	7.252GlyVal: 7.252 ± 0.081	1.703GlyTrp: 1.703 ± 0.037	2.089GlyTyr: 2.089 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	2.635HisAla: 2.635 ± 0.048	0.21HisCys: 0.21 ± 0.013	1.24HisAsp: 1.24 ± 0.036	0.9HisGlu: 0.9 ± 0.021	0.684HisPhe: 0.684 ± 0.022	1.942HisGly: 1.942 ± 0.04	0.456HisHis: 0.456 ± 0.02	0.648HisIle: 0.648 ± 0.023	0.321HisLys: 0.321 ± 0.015	1.717HisLeu: 1.717 ± 0.038	0.466HisMet: 0.466 ± 0.021	0.315HisAsn: 0.315 ± 0.015	1.407HisPro: 1.407 ± 0.035	0.389HisGln: 0.389 ± 0.014	1.243HisArg: 1.243 ± 0.034	0.728HisSer: 0.728 ± 0.024	0.629HisThr: 0.629 ± 0.024	1.366HisVal: 1.366 ± 0.031	0.275HisTrp: 0.275 ± 0.015	0.42HisTyr: 0.42 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.505IleAla: 6.505 ± 0.078	0.507IleCys: 0.507 ± 0.018	2.853IleAsp: 2.853 ± 0.05	3.052IleGlu: 3.052 ± 0.046	1.443IlePhe: 1.443 ± 0.037	4.498IleGly: 4.498 ± 0.065	0.79IleHis: 0.79 ± 0.022	1.324IleIle: 1.324 ± 0.037	0.894IleLys: 0.894 ± 0.026	3.873IleLeu: 3.873 ± 0.055	0.782IleMet: 0.782 ± 0.025	1.02IleAsn: 1.02 ± 0.028	2.251IlePro: 2.251 ± 0.044	0.847IleGln: 0.847 ± 0.027	3.114IleArg: 3.114 ± 0.044	2.323IleSer: 2.323 ± 0.046	2.028IleThr: 2.028 ± 0.044	3.073IleVal: 3.073 ± 0.051	0.57IleTrp: 0.57 ± 0.022	0.838IleTyr: 0.838 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.209LysAla: 3.209 ± 0.057	0.121LysCys: 0.121 ± 0.009	1.189LysAsp: 1.189 ± 0.035	1.011LysGlu: 1.011 ± 0.033	0.676LysPhe: 0.676 ± 0.025	2.118LysGly: 2.118 ± 0.044	0.358LysHis: 0.358 ± 0.018	1.139LysIle: 1.139 ± 0.032	0.746LysLys: 0.746 ± 0.031	2.327LysLeu: 2.327 ± 0.043	0.593LysMet: 0.593 ± 0.023	0.488LysAsn: 0.488 ± 0.023	1.357LysPro: 1.357 ± 0.034	0.478LysGln: 0.478 ± 0.018	1.687LysArg: 1.687 ± 0.042	1.198LysSer: 1.198 ± 0.032	1.365LysThr: 1.365 ± 0.036	1.777LysVal: 1.777 ± 0.046	0.254LysTrp: 0.254 ± 0.014	0.419LysTyr: 0.419 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	16.165LeuAla: 16.165 ± 0.162	0.895LeuCys: 0.895 ± 0.029	6.444LeuAsp: 6.444 ± 0.076	5.44LeuGlu: 5.44 ± 0.078	3.124LeuPhe: 3.124 ± 0.062	9.165LeuGly: 9.165 ± 0.086	1.812LeuHis: 1.812 ± 0.039	4.542LeuIle: 4.542 ± 0.072	2.378LeuLys: 2.378 ± 0.051	8.506LeuLeu: 8.506 ± 0.114	2.396LeuMet: 2.396 ± 0.045	2.107LeuAsn: 2.107 ± 0.041	5.623LeuPro: 5.623 ± 0.069	1.944LeuGln: 1.944 ± 0.039	8.044LeuArg: 8.044 ± 0.099	5.872LeuSer: 5.872 ± 0.072	5.692LeuThr: 5.692 ± 0.075	6.697LeuVal: 6.697 ± 0.073	1.224LeuTrp: 1.224 ± 0.033	1.638LeuTyr: 1.638 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	3.596MetAla: 3.596 ± 0.056	0.18MetCys: 0.18 ± 0.011	1.289MetAsp: 1.289 ± 0.033	1.352MetGlu: 1.352 ± 0.036	0.756MetPhe: 0.756 ± 0.021	2.222MetGly: 2.222 ± 0.045	0.384MetHis: 0.384 ± 0.015	1.348MetIle: 1.348 ± 0.027	0.749MetLys: 0.749 ± 0.024	2.462MetLeu: 2.462 ± 0.045	0.649MetMet: 0.649 ± 0.026	0.651MetAsn: 0.651 ± 0.022	1.358MetPro: 1.358 ± 0.034	0.672MetGln: 0.672 ± 0.021	2.058MetArg: 2.058 ± 0.046	1.641MetSer: 1.641 ± 0.031	2.225MetThr: 2.225 ± 0.041	1.669MetVal: 1.669 ± 0.034	0.239MetTrp: 0.239 ± 0.014	0.255MetTyr: 0.255 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.736AsnAla: 2.736 ± 0.049	0.178AsnCys: 0.178 ± 0.012	1.048AsnAsp: 1.048 ± 0.036	0.842AsnGlu: 0.842 ± 0.026	0.701AsnPhe: 0.701 ± 0.02	1.926AsnGly: 1.926 ± 0.057	0.364AsnHis: 0.364 ± 0.016	0.908AsnIle: 0.908 ± 0.03	0.397AsnLys: 0.397 ± 0.016	2.014AsnLeu: 2.014 ± 0.033	0.522AsnMet: 0.522 ± 0.021	0.443AsnAsn: 0.443 ± 0.021	1.565AsnPro: 1.565 ± 0.036	0.491AsnGln: 0.491 ± 0.016	1.364AsnArg: 1.364 ± 0.035	0.801AsnSer: 0.801 ± 0.028	0.858AsnThr: 0.858 ± 0.028	1.399AsnVal: 1.399 ± 0.034	0.301AsnTrp: 0.301 ± 0.015	0.455AsnTyr: 0.455 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	9.135ProAla: 9.135 ± 0.115	0.373ProCys: 0.373 ± 0.016	4.631ProAsp: 4.631 ± 0.068	4.963ProGlu: 4.963 ± 0.071	1.887ProPhe: 1.887 ± 0.038	6.25ProGly: 6.25 ± 0.063	1.042ProHis: 1.042 ± 0.024	2.044ProIle: 2.044 ± 0.051	1.221ProLys: 1.221 ± 0.034	5.13ProLeu: 5.13 ± 0.069	1.366ProMet: 1.366 ± 0.034	1.084ProAsn: 1.084 ± 0.027	3.596ProPro: 3.596 ± 0.078	1.334ProGln: 1.334 ± 0.031	4.102ProArg: 4.102 ± 0.077	2.852ProSer: 2.852 ± 0.048	2.528ProThr: 2.528 ± 0.041	4.255ProVal: 4.255 ± 0.049	0.807ProTrp: 0.807 ± 0.026	1.039ProTyr: 1.039 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.737GlnAla: 3.737 ± 0.052	0.157GlnCys: 0.157 ± 0.01	1.187GlnAsp: 1.187 ± 0.036	1.141GlnGlu: 1.141 ± 0.031	0.779GlnPhe: 0.779 ± 0.023	2.351GlnGly: 2.351 ± 0.046	0.373GlnHis: 0.373 ± 0.017	1.191GlnIle: 1.191 ± 0.031	0.589GlnLys: 0.589 ± 0.023	2.0GlnLeu: 2.0 ± 0.041	0.639GlnMet: 0.639 ± 0.022	0.475GlnAsn: 0.475 ± 0.019	1.259GlnPro: 1.259 ± 0.028	0.622GlnGln: 0.622 ± 0.026	1.793GlnArg: 1.793 ± 0.037	1.273GlnSer: 1.273 ± 0.036	1.266GlnThr: 1.266 ± 0.034	1.998GlnVal: 1.998 ± 0.038	0.284GlnTrp: 0.284 ± 0.014	0.38GlnTyr: 0.38 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	11.735ArgAla: 11.735 ± 0.126	0.511ArgCys: 0.511 ± 0.019	4.687ArgAsp: 4.687 ± 0.065	4.448ArgGlu: 4.448 ± 0.061	2.954ArgPhe: 2.954 ± 0.046	6.127ArgGly: 6.127 ± 0.086	1.53ArgHis: 1.53 ± 0.036	3.982ArgIle: 3.982 ± 0.051	1.804ArgLys: 1.804 ± 0.04	8.755ArgLeu: 8.755 ± 0.106	2.234ArgMet: 2.234 ± 0.042	1.494ArgAsn: 1.494 ± 0.033	4.77ArgPro: 4.77 ± 0.074	1.812ArgGln: 1.812 ± 0.035	7.084ArgArg: 7.084 ± 0.104	3.17ArgSer: 3.17 ± 0.053	3.119ArgThr: 3.119 ± 0.055	5.071ArgVal: 5.071 ± 0.065	1.064ArgTrp: 1.064 ± 0.032	1.423ArgTyr: 1.423 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.5SerAla: 6.5 ± 0.078	0.351SerCys: 0.351 ± 0.016	2.805SerAsp: 2.805 ± 0.066	2.532SerGlu: 2.532 ± 0.046	1.817SerPhe: 1.817 ± 0.039	5.609SerGly: 5.609 ± 0.08	0.88SerHis: 0.88 ± 0.028	2.059SerIle: 2.059 ± 0.048	0.999SerLys: 0.999 ± 0.03	4.611SerLeu: 4.611 ± 0.06	1.149SerMet: 1.149 ± 0.028	0.953SerAsn: 0.953 ± 0.028	2.896SerPro: 2.896 ± 0.052	1.158SerGln: 1.158 ± 0.027	3.473SerArg: 3.473 ± 0.051	2.294SerSer: 2.294 ± 0.049	2.065SerThr: 2.065 ± 0.04	3.48SerVal: 3.48 ± 0.06	0.654SerTrp: 0.654 ± 0.024	0.933SerTyr: 0.933 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	6.316ThrAla: 6.316 ± 0.073	0.389ThrCys: 0.389 ± 0.016	2.642ThrAsp: 2.642 ± 0.049	2.73ThrGlu: 2.73 ± 0.05	1.652ThrPhe: 1.652 ± 0.036	5.308ThrGly: 5.308 ± 0.075	0.909ThrHis: 0.909 ± 0.025	1.82ThrIle: 1.82 ± 0.046	0.764ThrLys: 0.764 ± 0.028	5.681ThrLeu: 5.681 ± 0.076	1.001ThrMet: 1.001 ± 0.028	0.909ThrAsn: 0.909 ± 0.029	3.622ThrPro: 3.622 ± 0.059	1.087ThrGln: 1.087 ± 0.031	3.611ThrArg: 3.611 ± 0.058	2.24ThrSer: 2.24 ± 0.043	2.162ThrThr: 2.162 ± 0.044	3.735ThrVal: 3.735 ± 0.073	0.665ThrTrp: 0.665 ± 0.021	0.951ThrTyr: 0.951 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	10.002ValAla: 10.002 ± 0.1	0.665ValCys: 0.665 ± 0.022	3.968ValAsp: 3.968 ± 0.058	4.645ValGlu: 4.645 ± 0.063	2.694ValPhe: 2.694 ± 0.047	5.597ValGly: 5.597 ± 0.081	1.205ValHis: 1.205 ± 0.034	3.723ValIle: 3.723 ± 0.054	1.718ValLys: 1.718 ± 0.04	6.385ValLeu: 6.385 ± 0.068	1.95ValMet: 1.95 ± 0.042	1.687ValAsn: 1.687 ± 0.044	3.16ValPro: 3.16 ± 0.047	1.576ValGln: 1.576 ± 0.035	4.561ValArg: 4.561 ± 0.061	4.145ValSer: 4.145 ± 0.069	4.194ValThr: 4.194 ± 0.086	5.279ValVal: 5.279 ± 0.076	0.989ValTrp: 0.989 ± 0.029	1.373ValTyr: 1.373 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.647TrpAla: 1.647 ± 0.038	0.119TrpCys: 0.119 ± 0.008	0.742TrpAsp: 0.742 ± 0.025	0.715TrpGlu: 0.715 ± 0.025	0.563TrpPhe: 0.563 ± 0.021	1.118TrpGly: 1.118 ± 0.031	0.24TrpHis: 0.24 ± 0.013	0.64TrpIle: 0.64 ± 0.021	0.427TrpLys: 0.427 ± 0.017	1.672TrpLeu: 1.672 ± 0.035	0.398TrpMet: 0.398 ± 0.019	0.37TrpAsn: 0.37 ± 0.017	0.79TrpPro: 0.79 ± 0.024	0.347TrpGln: 0.347 ± 0.016	1.445TrpArg: 1.445 ± 0.034	0.823TrpSer: 0.823 ± 0.026	0.937TrpThr: 0.937 ± 0.025	0.778TrpVal: 0.778 ± 0.024	0.231TrpTrp: 0.231 ± 0.012	0.239TrpTyr: 0.239 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.601TyrAla: 2.601 ± 0.045	0.163TyrCys: 0.163 ± 0.011	1.324TyrAsp: 1.324 ± 0.035	1.079TyrGlu: 1.079 ± 0.039	0.698TyrPhe: 0.698 ± 0.024	1.88TyrGly: 1.88 ± 0.037	0.379TyrHis: 0.379 ± 0.017	0.618TyrIle: 0.618 ± 0.02	0.394TyrLys: 0.394 ± 0.018	1.777TyrLeu: 1.777 ± 0.041	0.41TyrMet: 0.41 ± 0.017	0.416TyrAsn: 0.416 ± 0.017	0.93TyrPro: 0.93 ± 0.026	0.496TyrGln: 0.496 ± 0.02	1.376TyrArg: 1.376 ± 0.034	0.852TyrSer: 0.852 ± 0.026	0.823TyrThr: 0.823 ± 0.034	1.324TyrVal: 1.324 ± 0.03	0.309TyrTrp: 0.309 ± 0.015	0.453TyrTyr: 0.453 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4253 proteins (1441178 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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