Amino acid dipepetide frequency for Human fecal virus Jorvi4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.754AlaAla: 4.754 ± 2.876
0.0AlaCys: 0.0 ± 0.0
6.339AlaAsp: 6.339 ± 0.062
3.17AlaGlu: 3.17 ± 1.979
3.17AlaPhe: 3.17 ± 1.979
3.17AlaGly: 3.17 ± 1.917
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
7.924AlaLys: 7.924 ± 2.845
1.585AlaLeu: 1.585 ± 0.959
0.0AlaMet: 0.0 ± 0.787
4.754AlaAsn: 4.754 ± 0.928
1.585AlaPro: 1.585 ± 0.99
4.754AlaGln: 4.754 ± 1.02
4.754AlaArg: 4.754 ± 0.928
0.0AlaSer: 0.0 ± 0.0
6.339AlaThr: 6.339 ± 0.062
3.17AlaVal: 3.17 ± 1.917
0.0AlaTrp: 0.0 ± 0.0
4.754AlaTyr: 4.754 ± 0.928
0.0AlaXaa: 0.0 ± 0.0
Cys
3.17CysAla: 3.17 ± 0.031
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
3.17CysGlu: 3.17 ± 1.917
1.585CysPhe: 1.585 ± 0.99
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
3.17CysIle: 3.17 ± 1.979
1.585CysLys: 1.585 ± 0.959
1.585CysLeu: 1.585 ± 0.959
1.585CysMet: 1.585 ± 0.99
0.0CysAsn: 0.0 ± 0.0
1.585CysPro: 1.585 ± 0.99
0.0CysGln: 0.0 ± 0.0
1.585CysArg: 1.585 ± 0.959
0.0CysSer: 0.0 ± 0.0
3.17CysThr: 3.17 ± 1.979
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.17AspAla: 3.17 ± 0.031
0.0AspCys: 0.0 ± 0.0
3.17AspAsp: 3.17 ± 0.031
3.17AspGlu: 3.17 ± 1.979
3.17AspPhe: 3.17 ± 1.917
1.585AspGly: 1.585 ± 0.99
3.17AspHis: 3.17 ± 0.031
0.0AspIle: 0.0 ± 0.0
0.0AspLys: 0.0 ± 0.0
3.17AspLeu: 3.17 ± 0.031
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
7.924AspPro: 7.924 ± 2.845
3.17AspGln: 3.17 ± 1.979
1.585AspArg: 1.585 ± 0.99
0.0AspSer: 0.0 ± 0.0
4.754AspThr: 4.754 ± 2.969
1.585AspVal: 1.585 ± 0.99
3.17AspTrp: 3.17 ± 1.979
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.585GluAla: 1.585 ± 0.959
0.0GluCys: 0.0 ± 0.0
1.585GluAsp: 1.585 ± 0.99
3.17GluGlu: 3.17 ± 1.979
3.17GluPhe: 3.17 ± 0.031
3.17GluGly: 3.17 ± 1.979
3.17GluHis: 3.17 ± 1.979
1.585GluIle: 1.585 ± 0.99
4.754GluLys: 4.754 ± 1.02
4.754GluLeu: 4.754 ± 2.969
3.17GluMet: 3.17 ± 1.612
1.585GluAsn: 1.585 ± 0.959
1.585GluPro: 1.585 ± 0.99
3.17GluGln: 3.17 ± 1.979
3.17GluArg: 3.17 ± 1.979
4.754GluSer: 4.754 ± 1.02
4.754GluThr: 4.754 ± 2.876
0.0GluVal: 0.0 ± 0.0
1.585GluTrp: 1.585 ± 0.99
3.17GluTyr: 3.17 ± 0.031
0.0GluXaa: 0.0 ± 0.0
Phe
1.585PheAla: 1.585 ± 0.959
0.0PheCys: 0.0 ± 0.0
3.17PheAsp: 3.17 ± 1.979
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
1.585PheGly: 1.585 ± 0.959
1.585PheHis: 1.585 ± 0.959
3.17PheIle: 3.17 ± 0.031
4.754PheLys: 4.754 ± 2.876
1.585PheLeu: 1.585 ± 0.99
1.585PheMet: 1.585 ± 0.959
0.0PheAsn: 0.0 ± 0.0
3.17PhePro: 3.17 ± 1.979
0.0PheGln: 0.0 ± 0.0
3.17PheArg: 3.17 ± 0.031
1.585PheSer: 1.585 ± 0.959
6.339PheThr: 6.339 ± 0.062
3.17PheVal: 3.17 ± 0.031
0.0PheTrp: 0.0 ± 0.0
3.17PheTyr: 3.17 ± 0.031
0.0PheXaa: 0.0 ± 0.0
Gly
6.339GlyAla: 6.339 ± 1.887
0.0GlyCys: 0.0 ± 0.0
0.0GlyAsp: 0.0 ± 0.0
6.339GlyGlu: 6.339 ± 2.01
4.754GlyPhe: 4.754 ± 1.02
4.754GlyGly: 4.754 ± 0.928
1.585GlyHis: 1.585 ± 0.99
3.17GlyIle: 3.17 ± 0.031
7.924GlyLys: 7.924 ± 0.897
7.924GlyLeu: 7.924 ± 2.845
1.585GlyMet: 1.585 ± 0.959
4.754GlyAsn: 4.754 ± 0.928
6.339GlyPro: 6.339 ± 0.062
1.585GlyGln: 1.585 ± 0.99
6.339GlyArg: 6.339 ± 0.062
6.339GlySer: 6.339 ± 1.887
0.0GlyThr: 0.0 ± 0.0
1.585GlyVal: 1.585 ± 0.99
1.585GlyTrp: 1.585 ± 0.959
6.339GlyTyr: 6.339 ± 0.062
0.0GlyXaa: 0.0 ± 0.0
His
3.17HisAla: 3.17 ± 0.031
3.17HisCys: 3.17 ± 0.031
1.585HisAsp: 1.585 ± 0.99
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.585HisGly: 1.585 ± 0.99
0.0HisHis: 0.0 ± 0.0
3.17HisIle: 3.17 ± 1.979
0.0HisLys: 0.0 ± 0.0
1.585HisLeu: 1.585 ± 0.959
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
6.339HisPro: 6.339 ± 0.062
1.585HisGln: 1.585 ± 0.959
0.0HisArg: 0.0 ± 0.0
1.585HisSer: 1.585 ± 0.99
1.585HisThr: 1.585 ± 0.959
1.585HisVal: 1.585 ± 0.99
0.0HisTrp: 0.0 ± 0.0
1.585HisTyr: 1.585 ± 0.959
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.585IleCys: 1.585 ± 0.99
3.17IleAsp: 3.17 ± 1.979
3.17IleGlu: 3.17 ± 0.031
6.339IlePhe: 6.339 ± 2.01
6.339IleGly: 6.339 ± 1.887
1.585IleHis: 1.585 ± 0.99
1.585IleIle: 1.585 ± 0.99
4.754IleLys: 4.754 ± 1.02
3.17IleLeu: 3.17 ± 0.031
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
4.754IleGln: 4.754 ± 1.02
1.585IleArg: 1.585 ± 0.99
3.17IleSer: 3.17 ± 1.917
4.754IleThr: 4.754 ± 1.02
3.17IleVal: 3.17 ± 0.031
1.585IleTrp: 1.585 ± 0.99
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.585LysAla: 1.585 ± 0.99
1.585LysCys: 1.585 ± 0.959
3.17LysAsp: 3.17 ± 1.979
0.0LysGlu: 0.0 ± 0.0
3.17LysPhe: 3.17 ± 0.031
7.924LysGly: 7.924 ± 1.051
0.0LysHis: 0.0 ± 0.0
3.17LysIle: 3.17 ± 1.917
1.585LysLys: 1.585 ± 0.959
3.17LysLeu: 3.17 ± 1.979
1.585LysMet: 1.585 ± 0.959
4.754LysAsn: 4.754 ± 0.928
4.754LysPro: 4.754 ± 0.928
1.585LysGln: 1.585 ± 0.959
6.339LysArg: 6.339 ± 1.887
7.924LysSer: 7.924 ± 4.794
6.339LysThr: 6.339 ± 1.887
1.585LysVal: 1.585 ± 0.959
1.585LysTrp: 1.585 ± 0.959
3.17LysTyr: 3.17 ± 0.031
0.0LysXaa: 0.0 ± 0.0
Leu
1.585LeuAla: 1.585 ± 0.959
4.754LeuCys: 4.754 ± 2.969
1.585LeuAsp: 1.585 ± 0.99
1.585LeuGlu: 1.585 ± 0.99
1.585LeuPhe: 1.585 ± 0.959
9.509LeuGly: 9.509 ± 2.041
1.585LeuHis: 1.585 ± 0.99
7.924LeuIle: 7.924 ± 0.897
0.0LeuLys: 0.0 ± 0.0
4.754LeuLeu: 4.754 ± 0.928
1.585LeuMet: 1.585 ± 0.959
3.17LeuAsn: 3.17 ± 1.917
3.17LeuPro: 3.17 ± 1.917
4.754LeuGln: 4.754 ± 1.02
3.17LeuArg: 3.17 ± 0.031
4.754LeuSer: 4.754 ± 0.928
3.17LeuThr: 3.17 ± 0.031
4.754LeuVal: 4.754 ± 1.02
1.585LeuTrp: 1.585 ± 0.959
4.754LeuTyr: 4.754 ± 1.02
0.0LeuXaa: 0.0 ± 0.0
Met
4.754MetAla: 4.754 ± 1.02
0.0MetCys: 0.0 ± 0.0
1.585MetAsp: 1.585 ± 0.959
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
6.339MetGly: 6.339 ± 3.835
1.585MetHis: 1.585 ± 0.99
0.0MetIle: 0.0 ± 0.0
1.585MetLys: 1.585 ± 0.959
1.585MetLeu: 1.585 ± 0.99
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
3.17MetGln: 3.17 ± 1.979
1.585MetArg: 1.585 ± 0.99
3.17MetSer: 3.17 ± 0.031
1.585MetThr: 1.585 ± 0.959
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.585MetTyr: 1.585 ± 0.959
0.0MetXaa: 0.0 ± 0.0
Asn
3.17AsnAla: 3.17 ± 1.917
0.0AsnCys: 0.0 ± 0.0
1.585AsnAsp: 1.585 ± 0.99
4.754AsnGlu: 4.754 ± 2.876
1.585AsnPhe: 1.585 ± 0.959
1.585AsnGly: 1.585 ± 0.99
0.0AsnHis: 0.0 ± 0.0
3.17AsnIle: 3.17 ± 1.979
3.17AsnLys: 3.17 ± 0.031
1.585AsnLeu: 1.585 ± 0.99
1.585AsnMet: 1.585 ± 0.959
1.585AsnAsn: 1.585 ± 0.959
1.585AsnPro: 1.585 ± 0.959
0.0AsnGln: 0.0 ± 0.0
4.754AsnArg: 4.754 ± 1.02
0.0AsnSer: 0.0 ± 0.0
3.17AsnThr: 3.17 ± 0.031
1.585AsnVal: 1.585 ± 0.959
3.17AsnTrp: 3.17 ± 0.031
3.17AsnTyr: 3.17 ± 1.917
0.0AsnXaa: 0.0 ± 0.0
Pro
3.17ProAla: 3.17 ± 0.031
0.0ProCys: 0.0 ± 0.0
1.585ProAsp: 1.585 ± 0.959
3.17ProGlu: 3.17 ± 1.979
0.0ProPhe: 0.0 ± 0.0
4.754ProGly: 4.754 ± 0.928
4.754ProHis: 4.754 ± 0.928
1.585ProIle: 1.585 ± 0.99
1.585ProLys: 1.585 ± 0.959
1.585ProLeu: 1.585 ± 0.959
1.585ProMet: 1.585 ± 0.99
1.585ProAsn: 1.585 ± 0.99
1.585ProPro: 1.585 ± 0.99
1.585ProGln: 1.585 ± 0.99
3.17ProArg: 3.17 ± 0.031
3.17ProSer: 3.17 ± 0.031
4.754ProThr: 4.754 ± 1.02
7.924ProVal: 7.924 ± 2.845
0.0ProTrp: 0.0 ± 0.0
1.585ProTyr: 1.585 ± 0.959
0.0ProXaa: 0.0 ± 0.0
Gln
3.17GlnAla: 3.17 ± 0.031
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.754GlnGlu: 4.754 ± 2.969
0.0GlnPhe: 0.0 ± 0.0
3.17GlnGly: 3.17 ± 1.979
0.0GlnHis: 0.0 ± 0.0
1.585GlnIle: 1.585 ± 0.99
1.585GlnLys: 1.585 ± 0.99
4.754GlnLeu: 4.754 ± 1.02
0.0GlnMet: 0.0 ± 0.0
4.754GlnAsn: 4.754 ± 0.928
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
3.17GlnArg: 3.17 ± 0.031
3.17GlnSer: 3.17 ± 0.031
0.0GlnThr: 0.0 ± 0.0
3.17GlnVal: 3.17 ± 1.979
3.17GlnTrp: 3.17 ± 0.031
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.17ArgAla: 3.17 ± 0.031
1.585ArgCys: 1.585 ± 0.99
1.585ArgAsp: 1.585 ± 0.99
4.754ArgGlu: 4.754 ± 2.969
4.754ArgPhe: 4.754 ± 0.928
3.17ArgGly: 3.17 ± 1.917
3.17ArgHis: 3.17 ± 0.031
4.754ArgIle: 4.754 ± 1.02
6.339ArgLys: 6.339 ± 1.887
6.339ArgLeu: 6.339 ± 2.01
1.585ArgMet: 1.585 ± 0.959
0.0ArgAsn: 0.0 ± 0.0
1.585ArgPro: 1.585 ± 0.99
0.0ArgGln: 0.0 ± 0.0
6.339ArgArg: 6.339 ± 3.835
6.339ArgSer: 6.339 ± 2.01
6.339ArgThr: 6.339 ± 2.01
6.339ArgVal: 6.339 ± 0.062
1.585ArgTrp: 1.585 ± 0.99
9.509ArgTyr: 9.509 ± 1.856
0.0ArgXaa: 0.0 ± 0.0
Ser
4.754SerAla: 4.754 ± 1.02
1.585SerCys: 1.585 ± 0.959
4.754SerAsp: 4.754 ± 0.928
0.0SerGlu: 0.0 ± 0.0
4.754SerPhe: 4.754 ± 2.876
6.339SerGly: 6.339 ± 1.887
0.0SerHis: 0.0 ± 0.0
4.754SerIle: 4.754 ± 1.02
3.17SerLys: 3.17 ± 1.917
4.754SerLeu: 4.754 ± 2.876
3.17SerMet: 3.17 ± 1.979
4.754SerAsn: 4.754 ± 0.928
0.0SerPro: 0.0 ± 0.0
1.585SerGln: 1.585 ± 0.959
7.924SerArg: 7.924 ± 3.0
4.754SerSer: 4.754 ± 0.928
0.0SerThr: 0.0 ± 0.0
1.585SerVal: 1.585 ± 0.99
0.0SerTrp: 0.0 ± 0.0
1.585SerTyr: 1.585 ± 0.959
0.0SerXaa: 0.0 ± 0.0
Thr
4.754ThrAla: 4.754 ± 2.876
3.17ThrCys: 3.17 ± 1.917
3.17ThrAsp: 3.17 ± 0.031
4.754ThrGlu: 4.754 ± 1.02
0.0ThrPhe: 0.0 ± 0.0
6.339ThrGly: 6.339 ± 0.062
1.585ThrHis: 1.585 ± 0.99
4.754ThrIle: 4.754 ± 0.928
6.339ThrLys: 6.339 ± 2.01
4.754ThrLeu: 4.754 ± 0.928
4.754ThrMet: 4.754 ± 0.928
3.17ThrAsn: 3.17 ± 1.979
1.585ThrPro: 1.585 ± 0.959
1.585ThrGln: 1.585 ± 0.959
4.754ThrArg: 4.754 ± 1.02
4.754ThrSer: 4.754 ± 0.928
3.17ThrThr: 3.17 ± 0.031
1.585ThrVal: 1.585 ± 0.959
0.0ThrTrp: 0.0 ± 0.0
3.17ThrTyr: 3.17 ± 1.979
0.0ThrXaa: 0.0 ± 0.0
Val
1.585ValAla: 1.585 ± 0.959
1.585ValCys: 1.585 ± 0.99
3.17ValAsp: 3.17 ± 1.917
4.754ValGlu: 4.754 ± 1.02
0.0ValPhe: 0.0 ± 0.0
1.585ValGly: 1.585 ± 0.99
3.17ValHis: 3.17 ± 1.917
0.0ValIle: 0.0 ± 0.0
4.754ValLys: 4.754 ± 0.928
6.339ValLeu: 6.339 ± 2.01
0.0ValMet: 0.0 ± 0.0
1.585ValAsn: 1.585 ± 0.99
1.585ValPro: 1.585 ± 0.99
0.0ValGln: 0.0 ± 0.0
4.754ValArg: 4.754 ± 1.02
0.0ValSer: 0.0 ± 0.0
3.17ValThr: 3.17 ± 1.917
1.585ValVal: 1.585 ± 0.99
3.17ValTrp: 3.17 ± 1.917
3.17ValTyr: 3.17 ± 0.031
0.0ValXaa: 0.0 ± 0.0
Trp
1.585TrpAla: 1.585 ± 0.99
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.585TrpGlu: 1.585 ± 0.99
0.0TrpPhe: 0.0 ± 0.0
3.17TrpGly: 3.17 ± 0.031
0.0TrpHis: 0.0 ± 0.0
1.585TrpIle: 1.585 ± 0.99
0.0TrpLys: 0.0 ± 0.0
3.17TrpLeu: 3.17 ± 1.917
1.585TrpMet: 1.585 ± 0.959
3.17TrpAsn: 3.17 ± 0.031
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.585TrpArg: 1.585 ± 0.959
1.585TrpSer: 1.585 ± 0.99
1.585TrpThr: 1.585 ± 0.959
0.0TrpVal: 0.0 ± 0.0
1.585TrpTrp: 1.585 ± 0.99
1.585TrpTyr: 1.585 ± 0.99
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.754TyrAla: 4.754 ± 1.02
3.17TyrCys: 3.17 ± 0.031
1.585TyrAsp: 1.585 ± 0.99
1.585TyrGlu: 1.585 ± 0.99
1.585TyrPhe: 1.585 ± 0.959
3.17TyrGly: 3.17 ± 1.917
1.585TyrHis: 1.585 ± 0.959
1.585TyrIle: 1.585 ± 0.959
3.17TyrLys: 3.17 ± 1.917
1.585TyrLeu: 1.585 ± 0.99
1.585TyrMet: 1.585 ± 0.99
1.585TyrAsn: 1.585 ± 0.959
4.754TyrPro: 4.754 ± 0.928
3.17TyrGln: 3.17 ± 1.979
9.509TyrArg: 9.509 ± 0.093
3.17TyrSer: 3.17 ± 0.031
3.17TyrThr: 3.17 ± 1.917
1.585TyrVal: 1.585 ± 0.959
0.0TyrTrp: 0.0 ± 0.0
3.17TyrTyr: 3.17 ± 0.031
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (632 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski