Amino acid dipepetide frequency for Changjiang tombus-like virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.776AlaAla: 7.776 ± 3.766
0.0AlaCys: 0.0 ± 0.0
3.11AlaAsp: 3.11 ± 0.419
3.888AlaGlu: 3.888 ± 2.243
3.11AlaPhe: 3.11 ± 1.795
8.554AlaGly: 8.554 ± 1.942
1.555AlaHis: 1.555 ± 0.897
3.888AlaIle: 3.888 ± 0.868
3.11AlaLys: 3.11 ± 0.419
6.998AlaLeu: 6.998 ± 1.287
0.778AlaMet: 0.778 ± 0.258
5.443AlaAsn: 5.443 ± 0.39
1.555AlaPro: 1.555 ± 0.897
2.333AlaGln: 2.333 ± 2.78
2.333AlaArg: 2.333 ± 1.346
5.443AlaSer: 5.443 ± 3.736
7.776AlaThr: 7.776 ± 1.015
5.443AlaVal: 5.443 ± 3.736
0.778AlaTrp: 0.778 ± 0.449
2.333AlaTyr: 2.333 ± 0.029
0.778AlaXaa: 0.778 ± 0.449
Cys
2.333CysAla: 2.333 ± 1.346
0.778CysCys: 0.778 ± 0.449
1.555CysAsp: 1.555 ± 1.853
3.11CysGlu: 3.11 ± 1.795
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
2.333CysHis: 2.333 ± 0.029
0.778CysIle: 0.778 ± 0.449
1.555CysLys: 1.555 ± 0.897
2.333CysLeu: 2.333 ± 1.346
0.0CysMet: 0.0 ± 0.0
0.778CysAsn: 0.778 ± 0.449
0.778CysPro: 0.778 ± 0.449
0.778CysGln: 0.778 ± 0.449
0.778CysArg: 0.778 ± 0.449
0.778CysSer: 0.778 ± 0.449
1.555CysThr: 1.555 ± 0.478
1.555CysVal: 1.555 ± 0.897
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.333AspAla: 2.333 ± 1.346
1.555AspCys: 1.555 ± 0.897
0.778AspAsp: 0.778 ± 0.449
3.11AspGlu: 3.11 ± 0.419
3.11AspPhe: 3.11 ± 0.419
3.888AspGly: 3.888 ± 0.507
0.0AspHis: 0.0 ± 0.0
3.11AspIle: 3.11 ± 0.419
0.0AspLys: 0.0 ± 0.0
3.888AspLeu: 3.888 ± 0.868
2.333AspMet: 2.333 ± 1.346
3.11AspAsn: 3.11 ± 1.795
6.221AspPro: 6.221 ± 2.214
2.333AspGln: 2.333 ± 0.029
3.11AspArg: 3.11 ± 1.795
0.778AspSer: 0.778 ± 0.449
0.778AspThr: 0.778 ± 0.449
3.888AspVal: 3.888 ± 2.243
0.0AspTrp: 0.0 ± 0.0
0.778AspTyr: 0.778 ± 0.927
0.0AspXaa: 0.0 ± 0.0
Glu
2.333GluAla: 2.333 ± 0.029
3.11GluCys: 3.11 ± 0.419
3.11GluAsp: 3.11 ± 1.795
2.333GluGlu: 2.333 ± 1.346
3.888GluPhe: 3.888 ± 1.883
2.333GluGly: 2.333 ± 0.029
3.11GluHis: 3.11 ± 1.795
3.888GluIle: 3.888 ± 0.868
2.333GluLys: 2.333 ± 1.346
7.776GluLeu: 7.776 ± 1.015
2.333GluMet: 2.333 ± 0.029
2.333GluAsn: 2.333 ± 2.78
4.666GluPro: 4.666 ± 2.692
1.555GluGln: 1.555 ± 0.897
2.333GluArg: 2.333 ± 1.346
2.333GluSer: 2.333 ± 1.346
0.0GluThr: 0.0 ± 0.0
6.221GluVal: 6.221 ± 2.214
3.888GluTrp: 3.888 ± 0.868
1.555GluTyr: 1.555 ± 1.853
0.0GluXaa: 0.0 ± 0.0
Phe
2.333PheAla: 2.333 ± 1.405
2.333PheCys: 2.333 ± 0.029
0.778PheAsp: 0.778 ± 0.449
1.555PheGlu: 1.555 ± 0.897
0.778PhePhe: 0.778 ± 0.449
2.333PheGly: 2.333 ± 1.346
0.778PheHis: 0.778 ± 0.927
0.778PheIle: 0.778 ± 0.449
2.333PheLys: 2.333 ± 1.346
2.333PheLeu: 2.333 ± 1.346
0.0PheMet: 0.0 ± 0.0
0.778PheAsn: 0.778 ± 0.927
1.555PhePro: 1.555 ± 1.853
1.555PheGln: 1.555 ± 0.478
1.555PheArg: 1.555 ± 0.897
1.555PheSer: 1.555 ± 0.897
3.888PheThr: 3.888 ± 1.883
3.888PheVal: 3.888 ± 0.868
0.0PheTrp: 0.0 ± 0.0
0.778PheTyr: 0.778 ± 0.449
0.0PheXaa: 0.0 ± 0.0
Gly
5.443GlyAla: 5.443 ± 2.361
2.333GlyCys: 2.333 ± 1.346
5.443GlyAsp: 5.443 ± 0.39
6.998GlyGlu: 6.998 ± 0.088
4.666GlyPhe: 4.666 ± 0.059
7.776GlyGly: 7.776 ± 3.766
0.0GlyHis: 0.0 ± 0.0
4.666GlyIle: 4.666 ± 1.434
2.333GlyLys: 2.333 ± 0.029
10.109GlyLeu: 10.109 ± 1.706
3.888GlyMet: 3.888 ± 1.883
3.11GlyAsn: 3.11 ± 0.956
3.11GlyPro: 3.11 ± 0.956
2.333GlyGln: 2.333 ± 1.405
6.998GlyArg: 6.998 ± 1.287
5.443GlySer: 5.443 ± 6.487
3.11GlyThr: 3.11 ± 2.331
8.554GlyVal: 8.554 ± 2.184
0.0GlyTrp: 0.0 ± 0.0
0.778GlyTyr: 0.778 ± 0.449
0.0GlyXaa: 0.0 ± 0.0
His
0.778HisAla: 0.778 ± 0.449
0.0HisCys: 0.0 ± 0.0
2.333HisAsp: 2.333 ± 1.346
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.333HisGly: 2.333 ± 1.346
0.778HisHis: 0.778 ± 0.449
0.0HisIle: 0.0 ± 0.0
2.333HisLys: 2.333 ± 1.405
0.778HisLeu: 0.778 ± 0.449
0.0HisMet: 0.0 ± 0.0
0.778HisAsn: 0.778 ± 0.449
3.11HisPro: 3.11 ± 0.419
1.555HisGln: 1.555 ± 0.897
3.11HisArg: 3.11 ± 1.795
1.555HisSer: 1.555 ± 0.478
0.778HisThr: 0.778 ± 0.449
2.333HisVal: 2.333 ± 1.346
0.0HisTrp: 0.0 ± 0.0
1.555HisTyr: 1.555 ± 0.478
0.0HisXaa: 0.0 ± 0.0
Ile
4.666IleAla: 4.666 ± 0.059
0.0IleCys: 0.0 ± 0.0
0.778IleAsp: 0.778 ± 0.927
5.443IleGlu: 5.443 ± 0.39
0.0IlePhe: 0.0 ± 0.0
6.221IleGly: 6.221 ± 0.838
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
2.333IleLys: 2.333 ± 0.029
0.778IleLeu: 0.778 ± 0.927
1.555IleMet: 1.555 ± 0.897
1.555IleAsn: 1.555 ± 0.897
0.778IlePro: 0.778 ± 0.449
1.555IleGln: 1.555 ± 0.897
2.333IleArg: 2.333 ± 0.029
3.888IleSer: 3.888 ± 0.507
3.888IleThr: 3.888 ± 3.258
0.0IleVal: 0.0 ± 0.0
0.778IleTrp: 0.778 ± 0.927
1.555IleTyr: 1.555 ± 0.897
0.0IleXaa: 0.0 ± 0.0
Lys
5.443LysAla: 5.443 ± 0.39
0.778LysCys: 0.778 ± 0.449
3.11LysAsp: 3.11 ± 1.795
3.11LysGlu: 3.11 ± 0.956
0.778LysPhe: 0.778 ± 0.449
2.333LysGly: 2.333 ± 1.346
1.555LysHis: 1.555 ± 0.897
0.778LysIle: 0.778 ± 0.927
7.776LysLys: 7.776 ± 3.766
4.666LysLeu: 4.666 ± 1.317
3.11LysMet: 3.11 ± 0.419
1.555LysAsn: 1.555 ± 0.478
3.11LysPro: 3.11 ± 0.419
0.778LysGln: 0.778 ± 0.449
1.555LysArg: 1.555 ± 0.897
1.555LysSer: 1.555 ± 0.478
3.11LysThr: 3.11 ± 0.419
2.333LysVal: 2.333 ± 0.029
1.555LysTrp: 1.555 ± 0.897
2.333LysTyr: 2.333 ± 1.405
0.0LysXaa: 0.0 ± 0.0
Leu
6.998LeuAla: 6.998 ± 2.662
3.11LeuCys: 3.11 ± 1.795
3.888LeuAsp: 3.888 ± 0.868
6.998LeuGlu: 6.998 ± 2.662
0.778LeuPhe: 0.778 ± 0.449
9.331LeuGly: 9.331 ± 5.619
1.555LeuHis: 1.555 ± 0.478
0.0LeuIle: 0.0 ± 0.0
3.11LeuLys: 3.11 ± 0.419
11.664LeuLeu: 11.664 ± 3.979
3.11LeuMet: 3.11 ± 0.327
3.888LeuAsn: 3.888 ± 0.507
2.333LeuPro: 2.333 ± 0.029
2.333LeuGln: 2.333 ± 1.346
10.886LeuArg: 10.886 ± 0.596
6.998LeuSer: 6.998 ± 0.088
7.776LeuThr: 7.776 ± 5.141
2.333LeuVal: 2.333 ± 1.346
0.778LeuTrp: 0.778 ± 0.449
1.555LeuTyr: 1.555 ± 0.478
0.0LeuXaa: 0.0 ± 0.0
Met
0.778MetAla: 0.778 ± 0.449
0.0MetCys: 0.0 ± 0.0
1.555MetAsp: 1.555 ± 0.897
1.555MetGlu: 1.555 ± 0.897
1.555MetPhe: 1.555 ± 0.478
1.555MetGly: 1.555 ± 0.897
2.333MetHis: 2.333 ± 0.029
0.778MetIle: 0.778 ± 0.927
1.555MetLys: 1.555 ± 0.478
0.778MetLeu: 0.778 ± 0.449
0.778MetMet: 0.778 ± 0.927
1.555MetAsn: 1.555 ± 0.478
0.778MetPro: 0.778 ± 0.927
1.555MetGln: 1.555 ± 0.478
0.0MetArg: 0.0 ± 0.0
3.11MetSer: 3.11 ± 1.795
1.555MetThr: 1.555 ± 0.478
3.888MetVal: 3.888 ± 0.507
0.778MetTrp: 0.778 ± 0.449
1.555MetTyr: 1.555 ± 0.478
0.0MetXaa: 0.0 ± 0.0
Asn
3.888AsnAla: 3.888 ± 0.507
0.778AsnCys: 0.778 ± 0.449
1.555AsnAsp: 1.555 ± 0.478
1.555AsnGlu: 1.555 ± 0.478
0.778AsnPhe: 0.778 ± 0.927
0.778AsnGly: 0.778 ± 0.449
0.0AsnHis: 0.0 ± 0.0
3.11AsnIle: 3.11 ± 1.795
2.333AsnLys: 2.333 ± 0.029
3.11AsnLeu: 3.11 ± 0.956
0.778AsnMet: 0.778 ± 0.927
1.555AsnAsn: 1.555 ± 0.897
4.666AsnPro: 4.666 ± 2.81
1.555AsnGln: 1.555 ± 0.478
4.666AsnArg: 4.666 ± 2.692
1.555AsnSer: 1.555 ± 1.853
4.666AsnThr: 4.666 ± 1.434
3.888AsnVal: 3.888 ± 0.868
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.333ProAla: 2.333 ± 1.405
1.555ProCys: 1.555 ± 0.478
3.888ProAsp: 3.888 ± 2.243
0.778ProGlu: 0.778 ± 0.449
0.778ProPhe: 0.778 ± 0.927
5.443ProGly: 5.443 ± 0.986
0.778ProHis: 0.778 ± 0.449
2.333ProIle: 2.333 ± 0.029
3.888ProLys: 3.888 ± 0.507
2.333ProLeu: 2.333 ± 0.029
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
4.666ProPro: 4.666 ± 0.059
0.0ProGln: 0.0 ± 0.0
3.888ProArg: 3.888 ± 2.243
3.888ProSer: 3.888 ± 0.868
5.443ProThr: 5.443 ± 1.765
7.776ProVal: 7.776 ± 1.736
1.555ProTrp: 1.555 ± 0.478
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.555GlnAla: 1.555 ± 0.478
0.778GlnCys: 0.778 ± 0.449
0.778GlnAsp: 0.778 ± 0.449
0.778GlnGlu: 0.778 ± 0.449
0.778GlnPhe: 0.778 ± 0.449
2.333GlnGly: 2.333 ± 2.78
0.778GlnHis: 0.778 ± 0.449
2.333GlnIle: 2.333 ± 0.029
3.11GlnLys: 3.11 ± 0.419
1.555GlnLeu: 1.555 ± 0.897
1.555GlnMet: 1.555 ± 0.897
0.778GlnAsn: 0.778 ± 0.927
3.11GlnPro: 3.11 ± 1.795
2.333GlnGln: 2.333 ± 0.029
0.778GlnArg: 0.778 ± 0.449
0.0GlnSer: 0.0 ± 0.0
2.333GlnThr: 2.333 ± 2.78
1.555GlnVal: 1.555 ± 0.897
0.0GlnTrp: 0.0 ± 0.0
2.333GlnTyr: 2.333 ± 1.405
0.0GlnXaa: 0.0 ± 0.0
Arg
7.776ArgAla: 7.776 ± 1.736
1.555ArgCys: 1.555 ± 0.897
3.11ArgAsp: 3.11 ± 1.795
5.443ArgGlu: 5.443 ± 3.141
3.11ArgPhe: 3.11 ± 1.795
4.666ArgGly: 4.666 ± 0.059
2.333ArgHis: 2.333 ± 0.029
4.666ArgIle: 4.666 ± 0.059
3.11ArgLys: 3.11 ± 1.795
7.776ArgLeu: 7.776 ± 4.486
2.333ArgMet: 2.333 ± 1.346
3.11ArgAsn: 3.11 ± 1.795
3.11ArgPro: 3.11 ± 0.419
1.555ArgGln: 1.555 ± 0.478
6.221ArgArg: 6.221 ± 3.589
3.888ArgSer: 3.888 ± 0.868
2.333ArgThr: 2.333 ± 1.405
3.11ArgVal: 3.11 ± 0.419
0.778ArgTrp: 0.778 ± 0.927
1.555ArgTyr: 1.555 ± 0.478
0.0ArgXaa: 0.0 ± 0.0
Ser
5.443SerAla: 5.443 ± 0.986
0.778SerCys: 0.778 ± 0.449
2.333SerAsp: 2.333 ± 1.346
5.443SerGlu: 5.443 ± 2.361
0.778SerPhe: 0.778 ± 0.449
7.776SerGly: 7.776 ± 1.015
1.555SerHis: 1.555 ± 0.897
3.11SerIle: 3.11 ± 0.419
2.333SerLys: 2.333 ± 0.029
5.443SerLeu: 5.443 ± 3.736
0.778SerMet: 0.778 ± 0.927
5.443SerAsn: 5.443 ± 0.986
0.778SerPro: 0.778 ± 0.449
0.778SerGln: 0.778 ± 0.927
1.555SerArg: 1.555 ± 0.478
2.333SerSer: 2.333 ± 1.405
3.888SerThr: 3.888 ± 1.883
6.221SerVal: 6.221 ± 3.288
0.778SerTrp: 0.778 ± 0.449
1.555SerTyr: 1.555 ± 1.853
0.0SerXaa: 0.0 ± 0.0
Thr
3.11ThrAla: 3.11 ± 0.956
0.0ThrCys: 0.0 ± 0.0
2.333ThrAsp: 2.333 ± 1.346
3.888ThrGlu: 3.888 ± 1.883
3.888ThrPhe: 3.888 ± 0.507
10.886ThrGly: 10.886 ± 4.722
2.333ThrHis: 2.333 ± 1.346
3.888ThrIle: 3.888 ± 3.258
0.778ThrLys: 0.778 ± 0.449
8.554ThrLeu: 8.554 ± 3.317
0.0ThrMet: 0.0 ± 0.0
0.778ThrAsn: 0.778 ± 0.927
0.778ThrPro: 0.778 ± 0.449
1.555ThrGln: 1.555 ± 0.897
3.11ThrArg: 3.11 ± 0.419
3.888ThrSer: 3.888 ± 4.634
4.666ThrThr: 4.666 ± 5.56
8.554ThrVal: 8.554 ± 3.317
0.0ThrTrp: 0.0 ± 0.0
1.555ThrTyr: 1.555 ± 0.478
0.0ThrXaa: 0.0 ± 0.0
Val
10.109ValAla: 10.109 ± 2.42
0.0ValCys: 0.0 ± 0.0
3.888ValAsp: 3.888 ± 2.243
3.11ValGlu: 3.11 ± 0.419
2.333ValPhe: 2.333 ± 0.029
6.998ValGly: 6.998 ± 0.088
2.333ValHis: 2.333 ± 1.346
0.0ValIle: 0.0 ± 0.0
5.443ValLys: 5.443 ± 0.39
6.221ValLeu: 6.221 ± 3.288
3.888ValMet: 3.888 ± 0.507
1.555ValAsn: 1.555 ± 0.478
5.443ValPro: 5.443 ± 0.39
1.555ValGln: 1.555 ± 0.478
8.554ValArg: 8.554 ± 2.184
3.888ValSer: 3.888 ± 0.507
5.443ValThr: 5.443 ± 0.986
10.886ValVal: 10.886 ± 0.596
0.778ValTrp: 0.778 ± 0.449
3.888ValTyr: 3.888 ± 2.243
0.0ValXaa: 0.0 ± 0.0
Trp
0.778TrpAla: 0.778 ± 0.927
1.555TrpCys: 1.555 ± 0.478
0.0TrpAsp: 0.0 ± 0.0
1.555TrpGlu: 1.555 ± 0.897
0.778TrpPhe: 0.778 ± 0.449
0.778TrpGly: 0.778 ± 0.449
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.778TrpLys: 0.778 ± 0.449
1.555TrpLeu: 1.555 ± 1.853
0.0TrpMet: 0.0 ± 0.0
0.778TrpAsn: 0.778 ± 0.927
0.778TrpPro: 0.778 ± 0.449
0.778TrpGln: 0.778 ± 0.449
0.778TrpArg: 0.778 ± 0.449
0.778TrpSer: 0.778 ± 0.449
1.555TrpThr: 1.555 ± 0.897
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.555TyrAla: 1.555 ± 0.897
0.778TyrCys: 0.778 ± 0.449
0.778TyrAsp: 0.778 ± 0.927
0.778TyrGlu: 0.778 ± 0.927
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.778TyrLys: 0.778 ± 0.449
0.778TyrLeu: 0.778 ± 0.449
0.0TyrMet: 0.0 ± 0.0
2.333TyrAsn: 2.333 ± 0.029
0.0TyrPro: 0.0 ± 0.0
0.778TyrGln: 0.778 ± 0.449
6.998TyrArg: 6.998 ± 0.088
5.443TyrSer: 5.443 ± 2.361
0.0TyrThr: 0.0 ± 0.0
3.888TyrVal: 3.888 ± 3.258
0.778TyrTrp: 0.778 ± 0.927
1.555TyrTyr: 1.555 ± 0.897
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.778XaaGly: 0.778 ± 0.449
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1287 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski