Amino acid dipepetide frequency for Arumowot virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.147AlaAla: 3.147 ± 2.283
1.311AlaCys: 1.311 ± 0.469
1.836AlaAsp: 1.836 ± 0.752
2.098AlaGlu: 2.098 ± 0.516
0.787AlaPhe: 0.787 ± 0.415
2.36AlaGly: 2.36 ± 1.575
1.049AlaHis: 1.049 ± 0.913
4.983AlaIle: 4.983 ± 1.458
2.098AlaLys: 2.098 ± 1.177
8.655AlaLeu: 8.655 ± 3.48
1.311AlaMet: 1.311 ± 0.973
1.574AlaAsn: 1.574 ± 0.531
1.049AlaPro: 1.049 ± 0.626
1.049AlaGln: 1.049 ± 1.151
3.147AlaArg: 3.147 ± 1.175
5.507AlaSer: 5.507 ± 1.451
3.147AlaThr: 3.147 ± 0.625
1.836AlaVal: 1.836 ± 1.088
0.525AlaTrp: 0.525 ± 0.177
1.836AlaTyr: 1.836 ± 0.598
0.0AlaXaa: 0.0 ± 0.0
Cys
0.525CysAla: 0.525 ± 0.527
0.262CysCys: 0.262 ± 0.171
2.098CysAsp: 2.098 ± 0.707
1.049CysGlu: 1.049 ± 0.569
3.147CysPhe: 3.147 ± 1.267
0.787CysGly: 0.787 ± 0.791
1.574CysHis: 1.574 ± 1.196
0.525CysIle: 0.525 ± 0.177
3.409CysLys: 3.409 ± 1.049
2.098CysLeu: 2.098 ± 1.346
0.525CysMet: 0.525 ± 0.342
0.525CysAsn: 0.525 ± 0.342
0.787CysPro: 0.787 ± 0.415
2.098CysGln: 2.098 ± 0.995
0.787CysArg: 0.787 ± 0.513
2.885CysSer: 2.885 ± 1.411
1.574CysThr: 1.574 ± 0.578
1.311CysVal: 1.311 ± 1.214
0.262CysTrp: 0.262 ± 0.264
1.049CysTyr: 1.049 ± 0.354
0.0CysXaa: 0.0 ± 0.0
Asp
3.934AspAla: 3.934 ± 2.882
1.049AspCys: 1.049 ± 0.673
6.294AspAsp: 6.294 ± 2.517
3.672AspGlu: 3.672 ± 1.065
2.885AspPhe: 2.885 ± 1.713
1.049AspGly: 1.049 ± 0.361
1.049AspHis: 1.049 ± 0.354
2.885AspIle: 2.885 ± 1.122
2.885AspLys: 2.885 ± 0.415
6.819AspLeu: 6.819 ± 2.685
1.311AspMet: 1.311 ± 0.714
3.409AspAsn: 3.409 ± 0.527
3.672AspPro: 3.672 ± 0.852
2.098AspGln: 2.098 ± 1.015
1.574AspArg: 1.574 ± 0.828
3.672AspSer: 3.672 ± 1.819
3.409AspThr: 3.409 ± 0.774
2.885AspVal: 2.885 ± 0.656
1.311AspTrp: 1.311 ± 0.517
1.311AspTyr: 1.311 ± 0.581
0.0AspXaa: 0.0 ± 0.0
Glu
2.885GluAla: 2.885 ± 0.903
2.623GluCys: 2.623 ± 0.884
3.672GluAsp: 3.672 ± 1.012
6.557GluGlu: 6.557 ± 1.722
4.196GluPhe: 4.196 ± 1.284
4.983GluGly: 4.983 ± 1.007
0.525GluHis: 0.525 ± 0.177
5.245GluIle: 5.245 ± 1.329
2.623GluLys: 2.623 ± 0.738
4.983GluLeu: 4.983 ± 2.117
1.574GluMet: 1.574 ± 1.026
1.836GluAsn: 1.836 ± 0.815
1.311GluPro: 1.311 ± 0.409
1.049GluGln: 1.049 ± 0.673
3.147GluArg: 3.147 ± 1.094
3.934GluSer: 3.934 ± 1.02
3.672GluThr: 3.672 ± 1.305
4.196GluVal: 4.196 ± 1.168
1.049GluTrp: 1.049 ± 0.673
2.623GluTyr: 2.623 ± 0.8
0.0GluXaa: 0.0 ± 0.0
Phe
2.098PheAla: 2.098 ± 0.411
1.836PheCys: 1.836 ± 1.086
2.36PheAsp: 2.36 ± 1.285
2.36PheGlu: 2.36 ± 1.746
2.098PhePhe: 2.098 ± 0.685
2.36PheGly: 2.36 ± 0.344
1.049PheHis: 1.049 ± 0.354
1.836PheIle: 1.836 ± 0.318
2.098PheLys: 2.098 ± 0.721
3.147PheLeu: 3.147 ± 1.122
0.525PheMet: 0.525 ± 0.342
1.836PheAsn: 1.836 ± 0.357
2.098PhePro: 2.098 ± 0.873
2.36PheGln: 2.36 ± 0.347
3.672PheArg: 3.672 ± 0.698
4.458PheSer: 4.458 ± 2.133
1.836PheThr: 1.836 ± 0.847
3.409PheVal: 3.409 ± 1.526
0.525PheTrp: 0.525 ± 0.177
0.787PheTyr: 0.787 ± 0.513
0.0PheXaa: 0.0 ± 0.0
Gly
3.147GlyAla: 3.147 ± 1.363
1.049GlyCys: 1.049 ± 0.354
2.36GlyAsp: 2.36 ± 1.336
3.672GlyGlu: 3.672 ± 1.07
2.885GlyPhe: 2.885 ± 0.425
4.196GlyGly: 4.196 ± 1.014
1.311GlyHis: 1.311 ± 0.855
6.557GlyIle: 6.557 ± 1.108
4.721GlyLys: 4.721 ± 0.501
4.983GlyLeu: 4.983 ± 1.382
2.885GlyMet: 2.885 ± 1.177
1.574GlyAsn: 1.574 ± 1.022
3.147GlyPro: 3.147 ± 0.92
0.787GlyGln: 0.787 ± 0.415
3.147GlyArg: 3.147 ± 0.679
7.868GlySer: 7.868 ± 2.35
2.623GlyThr: 2.623 ± 0.884
2.885GlyVal: 2.885 ± 0.875
0.525GlyTrp: 0.525 ± 0.342
1.311GlyTyr: 1.311 ± 0.517
0.0GlyXaa: 0.0 ± 0.0
His
0.262HisAla: 0.262 ± 0.264
0.787HisCys: 0.787 ± 0.415
1.574HisAsp: 1.574 ± 0.803
0.525HisGlu: 0.525 ± 0.342
1.311HisPhe: 1.311 ± 0.581
2.098HisGly: 2.098 ± 0.707
0.262HisHis: 0.262 ± 0.171
2.36HisIle: 2.36 ± 0.875
0.525HisLys: 0.525 ± 0.527
1.049HisLeu: 1.049 ± 0.354
0.0HisMet: 0.0 ± 0.0
0.787HisAsn: 0.787 ± 0.576
1.049HisPro: 1.049 ± 0.354
1.311HisGln: 1.311 ± 0.369
1.311HisArg: 1.311 ± 0.517
2.098HisSer: 2.098 ± 0.977
1.049HisThr: 1.049 ± 0.354
0.787HisVal: 0.787 ± 0.227
0.0HisTrp: 0.0 ± 0.0
0.525HisTyr: 0.525 ± 0.177
0.0HisXaa: 0.0 ± 0.0
Ile
2.623IleAla: 2.623 ± 0.819
1.574IleCys: 1.574 ± 0.531
4.983IleAsp: 4.983 ± 1.318
3.934IleGlu: 3.934 ± 0.613
1.836IlePhe: 1.836 ± 0.575
3.409IleGly: 3.409 ± 0.537
1.311IleHis: 1.311 ± 0.381
4.458IleIle: 4.458 ± 0.622
4.721IleLys: 4.721 ± 0.84
5.77IleLeu: 5.77 ± 0.623
1.311IleMet: 1.311 ± 0.469
2.36IleAsn: 2.36 ± 0.344
2.623IlePro: 2.623 ± 2.367
2.36IleGln: 2.36 ± 0.702
5.507IleArg: 5.507 ± 1.836
4.983IleSer: 4.983 ± 1.977
4.983IleThr: 4.983 ± 0.956
3.934IleVal: 3.934 ± 1.284
1.049IleTrp: 1.049 ± 0.361
2.885IleTyr: 2.885 ± 0.802
0.0IleXaa: 0.0 ± 0.0
Lys
3.672LysAla: 3.672 ± 0.551
2.623LysCys: 2.623 ± 0.407
2.885LysAsp: 2.885 ± 0.819
3.409LysGlu: 3.409 ± 0.717
1.049LysPhe: 1.049 ± 0.361
3.409LysGly: 3.409 ± 1.169
0.787LysHis: 0.787 ± 0.227
4.721LysIle: 4.721 ± 1.097
4.721LysLys: 4.721 ± 0.812
7.606LysLeu: 7.606 ± 1.297
1.574LysMet: 1.574 ± 1.022
2.623LysAsn: 2.623 ± 0.738
3.934LysPro: 3.934 ± 1.744
2.098LysGln: 2.098 ± 0.516
3.672LysArg: 3.672 ± 0.646
3.934LysSer: 3.934 ± 0.613
4.458LysThr: 4.458 ± 1.432
4.721LysVal: 4.721 ± 1.514
1.311LysTrp: 1.311 ± 0.517
2.885LysTyr: 2.885 ± 1.364
0.0LysXaa: 0.0 ± 0.0
Leu
4.458LeuAla: 4.458 ± 0.695
1.836LeuCys: 1.836 ± 0.945
4.721LeuAsp: 4.721 ± 2.027
6.819LeuGlu: 6.819 ± 0.727
4.196LeuPhe: 4.196 ± 1.47
5.77LeuGly: 5.77 ± 1.484
2.098LeuHis: 2.098 ± 0.721
7.606LeuIle: 7.606 ± 2.121
8.13LeuLys: 8.13 ± 1.673
5.507LeuLeu: 5.507 ± 1.088
2.623LeuMet: 2.623 ± 0.51
2.623LeuAsn: 2.623 ± 0.407
2.885LeuPro: 2.885 ± 0.492
3.934LeuGln: 3.934 ± 2.085
5.77LeuArg: 5.77 ± 2.426
11.539LeuSer: 11.539 ± 1.87
4.721LeuThr: 4.721 ± 0.429
4.196LeuVal: 4.196 ± 1.168
1.049LeuTrp: 1.049 ± 0.537
3.934LeuTyr: 3.934 ± 0.719
0.0LeuXaa: 0.0 ± 0.0
Met
1.049MetAla: 1.049 ± 0.374
0.262MetCys: 0.262 ± 0.171
2.885MetAsp: 2.885 ± 1.589
1.836MetGlu: 1.836 ± 0.945
1.049MetPhe: 1.049 ± 0.374
1.836MetGly: 1.836 ± 1.343
1.049MetHis: 1.049 ± 0.454
2.098MetIle: 2.098 ± 0.629
1.311MetLys: 1.311 ± 0.445
1.049MetLeu: 1.049 ± 0.684
1.574MetMet: 1.574 ± 1.552
1.311MetAsn: 1.311 ± 0.714
0.525MetPro: 0.525 ± 0.487
0.787MetGln: 0.787 ± 0.227
0.262MetArg: 0.262 ± 0.171
1.836MetSer: 1.836 ± 0.844
2.098MetThr: 2.098 ± 0.365
1.836MetVal: 1.836 ± 0.533
0.262MetTrp: 0.262 ± 0.171
0.262MetTyr: 0.262 ± 0.171
0.0MetXaa: 0.0 ± 0.0
Asn
2.098AsnAla: 2.098 ± 0.38
1.311AsnCys: 1.311 ± 0.934
1.311AsnAsp: 1.311 ± 0.517
1.311AsnGlu: 1.311 ± 0.517
2.36AsnPhe: 2.36 ± 0.867
3.934AsnGly: 3.934 ± 1.241
1.049AsnHis: 1.049 ± 0.361
1.836AsnIle: 1.836 ± 0.533
2.098AsnLys: 2.098 ± 0.909
5.507AsnLeu: 5.507 ± 1.704
0.787AsnMet: 0.787 ± 0.513
1.836AsnAsn: 1.836 ± 0.597
2.623AsnPro: 2.623 ± 0.371
1.574AsnGln: 1.574 ± 0.531
2.098AsnArg: 2.098 ± 0.715
2.36AsnSer: 2.36 ± 0.484
1.836AsnThr: 1.836 ± 0.752
3.147AsnVal: 3.147 ± 0.907
0.525AsnTrp: 0.525 ± 0.575
1.836AsnTyr: 1.836 ± 1.755
0.0AsnXaa: 0.0 ± 0.0
Pro
1.574ProAla: 1.574 ± 1.197
0.0ProCys: 0.0 ± 0.0
1.574ProAsp: 1.574 ± 0.68
4.196ProGlu: 4.196 ± 2.191
0.787ProPhe: 0.787 ± 0.415
3.147ProGly: 3.147 ± 1.618
0.525ProHis: 0.525 ± 0.177
2.36ProIle: 2.36 ± 0.551
1.311ProLys: 1.311 ± 0.369
3.409ProLeu: 3.409 ± 1.347
0.525ProMet: 0.525 ± 0.487
2.098ProAsn: 2.098 ± 0.685
0.787ProPro: 0.787 ± 0.522
2.36ProGln: 2.36 ± 0.702
2.36ProArg: 2.36 ± 0.903
5.507ProSer: 5.507 ± 1.598
2.623ProThr: 2.623 ± 0.928
3.409ProVal: 3.409 ± 0.731
1.049ProTrp: 1.049 ± 0.843
1.049ProTyr: 1.049 ± 0.374
0.0ProXaa: 0.0 ± 0.0
Gln
2.623GlnAla: 2.623 ± 2.068
1.049GlnCys: 1.049 ± 0.673
1.574GlnAsp: 1.574 ± 0.454
2.623GlnGlu: 2.623 ± 0.388
0.525GlnPhe: 0.525 ± 0.487
1.574GlnGly: 1.574 ± 0.68
0.787GlnHis: 0.787 ± 0.513
3.147GlnIle: 3.147 ± 0.699
3.934GlnLys: 3.934 ± 0.684
1.574GlnLeu: 1.574 ± 0.457
0.787GlnMet: 0.787 ± 0.227
1.311GlnAsn: 1.311 ± 0.581
1.574GlnPro: 1.574 ± 0.499
1.574GlnGln: 1.574 ± 0.578
0.262GlnArg: 0.262 ± 0.171
4.196GlnSer: 4.196 ± 1.767
2.36GlnThr: 2.36 ± 0.344
2.098GlnVal: 2.098 ± 0.995
0.262GlnTrp: 0.262 ± 0.53
1.574GlnTyr: 1.574 ± 0.83
0.0GlnXaa: 0.0 ± 0.0
Arg
3.147ArgAla: 3.147 ± 1.527
1.049ArgCys: 1.049 ± 0.877
4.196ArgAsp: 4.196 ± 1.21
4.458ArgGlu: 4.458 ± 1.457
1.574ArgPhe: 1.574 ± 0.803
3.672ArgGly: 3.672 ± 0.764
1.049ArgHis: 1.049 ± 1.055
2.623ArgIle: 2.623 ± 1.034
2.623ArgLys: 2.623 ± 0.664
4.196ArgLeu: 4.196 ± 1.207
1.049ArgMet: 1.049 ± 0.626
2.36ArgAsn: 2.36 ± 0.681
2.098ArgPro: 2.098 ± 0.721
1.311ArgGln: 1.311 ± 1.284
1.311ArgArg: 1.311 ± 0.517
5.245ArgSer: 5.245 ± 0.455
2.098ArgThr: 2.098 ± 0.721
3.409ArgVal: 3.409 ± 1.088
0.787ArgTrp: 0.787 ± 0.501
1.049ArgTyr: 1.049 ± 0.684
0.0ArgXaa: 0.0 ± 0.0
Ser
4.721SerAla: 4.721 ± 0.555
3.934SerCys: 3.934 ± 3.242
3.934SerAsp: 3.934 ± 1.143
5.507SerGlu: 5.507 ± 0.441
6.557SerPhe: 6.557 ± 0.67
5.77SerGly: 5.77 ± 1.554
1.574SerHis: 1.574 ± 0.499
5.245SerIle: 5.245 ± 0.945
7.343SerLys: 7.343 ± 1.549
10.49SerLeu: 10.49 ± 0.487
2.098SerMet: 2.098 ± 0.411
4.458SerAsn: 4.458 ± 0.626
4.458SerPro: 4.458 ± 0.724
2.36SerGln: 2.36 ± 0.681
3.934SerArg: 3.934 ± 1.409
9.966SerSer: 9.966 ± 0.267
4.196SerThr: 4.196 ± 2.322
5.77SerVal: 5.77 ± 1.382
1.836SerTrp: 1.836 ± 0.452
2.098SerTyr: 2.098 ± 1.315
0.0SerXaa: 0.0 ± 0.0
Thr
2.36ThrAla: 2.36 ± 0.735
1.311ThrCys: 1.311 ± 0.934
2.623ThrAsp: 2.623 ± 0.8
3.672ThrGlu: 3.672 ± 1.069
1.311ThrPhe: 1.311 ± 0.469
3.934ThrGly: 3.934 ± 0.505
0.525ThrHis: 0.525 ± 0.177
3.934ThrIle: 3.934 ± 1.45
3.934ThrLys: 3.934 ± 0.847
6.819ThrLeu: 6.819 ± 0.918
1.311ThrMet: 1.311 ± 1.506
2.098ThrAsn: 2.098 ± 1.015
3.934ThrPro: 3.934 ± 1.052
2.623ThrGln: 2.623 ± 0.677
2.623ThrArg: 2.623 ± 0.653
6.032ThrSer: 6.032 ± 1.325
4.196ThrThr: 4.196 ± 0.933
3.147ThrVal: 3.147 ± 0.577
0.0ThrTrp: 0.0 ± 0.0
1.836ThrTyr: 1.836 ± 0.533
0.0ThrXaa: 0.0 ± 0.0
Val
3.672ValAla: 3.672 ± 1.272
2.098ValCys: 2.098 ± 0.665
4.196ValAsp: 4.196 ± 0.098
2.623ValGlu: 2.623 ± 1.353
2.36ValPhe: 2.36 ± 0.875
3.934ValGly: 3.934 ± 0.989
1.049ValHis: 1.049 ± 0.354
1.836ValIle: 1.836 ± 1.196
4.196ValLys: 4.196 ± 1.234
5.77ValLeu: 5.77 ± 1.112
3.147ValMet: 3.147 ± 0.735
3.409ValAsn: 3.409 ± 1.023
0.525ValPro: 0.525 ± 0.342
2.623ValGln: 2.623 ± 0.455
2.885ValArg: 2.885 ± 0.936
6.032ValSer: 6.032 ± 1.287
3.934ValThr: 3.934 ± 0.101
5.507ValVal: 5.507 ± 0.906
0.787ValTrp: 0.787 ± 0.513
0.787ValTyr: 0.787 ± 0.501
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.787TrpCys: 0.787 ± 0.513
0.787TrpAsp: 0.787 ± 0.501
0.787TrpGlu: 0.787 ± 0.227
0.525TrpPhe: 0.525 ± 0.177
1.049TrpGly: 1.049 ± 0.957
0.0TrpHis: 0.0 ± 0.0
0.525TrpIle: 0.525 ± 0.342
0.787TrpLys: 0.787 ± 0.739
1.836TrpLeu: 1.836 ± 0.533
0.0TrpMet: 0.0 ± 0.0
0.787TrpAsn: 0.787 ± 0.227
0.525TrpPro: 0.525 ± 0.487
0.0TrpGln: 0.0 ± 0.0
0.787TrpArg: 0.787 ± 0.501
0.525TrpSer: 0.525 ± 0.342
1.836TrpThr: 1.836 ± 0.815
1.311TrpVal: 1.311 ± 0.517
0.262TrpTrp: 0.262 ± 0.171
0.262TrpTyr: 0.262 ± 0.171
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.311TyrAla: 1.311 ± 0.469
0.525TyrCys: 0.525 ± 0.177
1.311TyrAsp: 1.311 ± 0.409
1.574TyrGlu: 1.574 ± 0.324
1.311TyrPhe: 1.311 ± 0.855
2.36TyrGly: 2.36 ± 0.681
1.049TyrHis: 1.049 ± 0.684
1.836TyrIle: 1.836 ± 0.575
2.623TyrLys: 2.623 ± 0.388
3.147TyrLeu: 3.147 ± 0.787
0.262TyrMet: 0.262 ± 0.171
2.623TyrAsn: 2.623 ± 0.928
1.049TyrPro: 1.049 ± 0.823
1.049TyrGln: 1.049 ± 0.537
1.049TyrArg: 1.049 ± 0.354
3.672TyrSer: 3.672 ± 0.551
1.574TyrThr: 1.574 ± 0.454
1.574TyrVal: 1.574 ± 0.578
0.0TyrTrp: 0.0 ± 0.0
1.311TyrTyr: 1.311 ± 0.369
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3814 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski