Amino acid dipepetide frequency for Pantoea phage vB_PagP-SK1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.358AlaAla: 11.358 ± 1.203
0.434AlaCys: 0.434 ± 0.195
5.462AlaAsp: 5.462 ± 0.783
5.809AlaGlu: 5.809 ± 0.693
3.988AlaPhe: 3.988 ± 0.559
8.93AlaGly: 8.93 ± 0.899
1.734AlaHis: 1.734 ± 0.379
4.508AlaIle: 4.508 ± 0.794
7.456AlaLys: 7.456 ± 0.815
8.497AlaLeu: 8.497 ± 0.965
3.815AlaMet: 3.815 ± 0.775
3.728AlaAsn: 3.728 ± 0.506
3.468AlaPro: 3.468 ± 0.649
5.636AlaGln: 5.636 ± 1.086
5.202AlaArg: 5.202 ± 0.857
6.503AlaSer: 6.503 ± 0.933
4.682AlaThr: 4.682 ± 0.681
6.242AlaVal: 6.242 ± 0.665
1.561AlaTrp: 1.561 ± 0.437
3.555AlaTyr: 3.555 ± 0.629
0.0AlaXaa: 0.0 ± 0.0
Cys
0.954CysAla: 0.954 ± 0.397
0.0CysCys: 0.0 ± 0.0
0.607CysAsp: 0.607 ± 0.316
0.52CysGlu: 0.52 ± 0.176
0.434CysPhe: 0.434 ± 0.245
0.347CysGly: 0.347 ± 0.195
0.173CysHis: 0.173 ± 0.116
0.347CysIle: 0.347 ± 0.179
0.26CysLys: 0.26 ± 0.173
0.434CysLeu: 0.434 ± 0.224
0.173CysMet: 0.173 ± 0.099
0.434CysAsn: 0.434 ± 0.289
0.434CysPro: 0.434 ± 0.225
0.347CysGln: 0.347 ± 0.177
0.694CysArg: 0.694 ± 0.317
0.607CysSer: 0.607 ± 0.312
0.173CysThr: 0.173 ± 0.118
0.607CysVal: 0.607 ± 0.173
0.087CysTrp: 0.087 ± 0.097
0.434CysTyr: 0.434 ± 0.251
0.0CysXaa: 0.0 ± 0.0
Asp
5.896AspAla: 5.896 ± 0.765
0.347AspCys: 0.347 ± 0.162
4.335AspAsp: 4.335 ± 0.728
4.248AspGlu: 4.248 ± 0.579
2.948AspPhe: 2.948 ± 0.411
6.936AspGly: 6.936 ± 0.808
1.127AspHis: 1.127 ± 0.307
3.035AspIle: 3.035 ± 0.455
3.988AspLys: 3.988 ± 0.633
4.075AspLeu: 4.075 ± 0.653
1.821AspMet: 1.821 ± 0.389
2.254AspAsn: 2.254 ± 0.41
3.208AspPro: 3.208 ± 0.623
2.948AspGln: 2.948 ± 0.504
2.514AspArg: 2.514 ± 0.338
4.248AspSer: 4.248 ± 0.578
4.248AspThr: 4.248 ± 0.417
4.075AspVal: 4.075 ± 0.729
0.78AspTrp: 0.78 ± 0.253
2.861AspTyr: 2.861 ± 0.52
0.0AspXaa: 0.0 ± 0.0
Glu
6.849GluAla: 6.849 ± 0.882
0.694GluCys: 0.694 ± 0.258
3.815GluAsp: 3.815 ± 0.514
5.115GluGlu: 5.115 ± 0.705
2.774GluPhe: 2.774 ± 0.583
5.375GluGly: 5.375 ± 0.697
1.387GluHis: 1.387 ± 0.546
3.468GluIle: 3.468 ± 0.585
2.948GluLys: 2.948 ± 0.533
4.595GluLeu: 4.595 ± 0.649
2.601GluMet: 2.601 ± 0.462
2.428GluAsn: 2.428 ± 0.402
1.561GluPro: 1.561 ± 0.383
3.381GluGln: 3.381 ± 0.545
3.728GluArg: 3.728 ± 0.523
4.075GluSer: 4.075 ± 0.49
3.641GluThr: 3.641 ± 0.433
4.335GluVal: 4.335 ± 0.607
0.867GluTrp: 0.867 ± 0.176
2.254GluTyr: 2.254 ± 0.513
0.0GluXaa: 0.0 ± 0.0
Phe
3.902PheAla: 3.902 ± 0.501
0.26PheCys: 0.26 ± 0.202
3.208PheAsp: 3.208 ± 0.7
1.734PheGlu: 1.734 ± 0.615
1.127PhePhe: 1.127 ± 0.306
3.815PheGly: 3.815 ± 0.458
0.607PheHis: 0.607 ± 0.288
1.127PheIle: 1.127 ± 0.391
2.774PheLys: 2.774 ± 0.523
3.641PheLeu: 3.641 ± 0.536
1.214PheMet: 1.214 ± 0.274
2.601PheAsn: 2.601 ± 0.582
1.301PhePro: 1.301 ± 0.42
1.127PheGln: 1.127 ± 0.412
1.907PheArg: 1.907 ± 0.342
2.081PheSer: 2.081 ± 0.48
1.821PheThr: 1.821 ± 0.381
2.168PheVal: 2.168 ± 0.552
0.26PheTrp: 0.26 ± 0.156
0.954PheTyr: 0.954 ± 0.305
0.0PheXaa: 0.0 ± 0.0
Gly
9.19GlyAla: 9.19 ± 1.098
0.52GlyCys: 0.52 ± 0.226
5.982GlyAsp: 5.982 ± 0.901
5.722GlyGlu: 5.722 ± 0.655
3.555GlyPhe: 3.555 ± 0.693
5.896GlyGly: 5.896 ± 0.543
1.04GlyHis: 1.04 ± 0.296
5.202GlyIle: 5.202 ± 0.753
5.722GlyLys: 5.722 ± 0.582
6.936GlyLeu: 6.936 ± 0.932
2.168GlyMet: 2.168 ± 0.479
2.601GlyAsn: 2.601 ± 0.5
1.387GlyPro: 1.387 ± 0.338
3.468GlyGln: 3.468 ± 0.556
4.682GlyArg: 4.682 ± 0.591
4.855GlySer: 4.855 ± 0.652
3.381GlyThr: 3.381 ± 0.629
4.595GlyVal: 4.595 ± 0.489
1.387GlyTrp: 1.387 ± 0.473
2.428GlyTyr: 2.428 ± 0.556
0.0GlyXaa: 0.0 ± 0.0
His
1.474HisAla: 1.474 ± 0.316
0.347HisCys: 0.347 ± 0.213
1.04HisAsp: 1.04 ± 0.279
1.214HisGlu: 1.214 ± 0.372
1.04HisPhe: 1.04 ± 0.301
1.474HisGly: 1.474 ± 0.381
0.347HisHis: 0.347 ± 0.149
0.867HisIle: 0.867 ± 0.277
1.127HisLys: 1.127 ± 0.252
1.647HisLeu: 1.647 ± 0.341
0.78HisMet: 0.78 ± 0.186
0.347HisAsn: 0.347 ± 0.167
0.694HisPro: 0.694 ± 0.194
0.087HisGln: 0.087 ± 0.104
0.434HisArg: 0.434 ± 0.208
1.04HisSer: 1.04 ± 0.374
1.301HisThr: 1.301 ± 0.334
1.214HisVal: 1.214 ± 0.369
0.52HisTrp: 0.52 ± 0.13
0.434HisTyr: 0.434 ± 0.186
0.0HisXaa: 0.0 ± 0.0
Ile
3.988IleAla: 3.988 ± 0.518
0.26IleCys: 0.26 ± 0.15
3.641IleAsp: 3.641 ± 0.507
2.774IleGlu: 2.774 ± 0.618
0.694IlePhe: 0.694 ± 0.273
4.248IleGly: 4.248 ± 0.503
0.954IleHis: 0.954 ± 0.318
2.254IleIle: 2.254 ± 0.577
3.902IleLys: 3.902 ± 0.501
3.902IleLeu: 3.902 ± 0.583
1.301IleMet: 1.301 ± 0.279
2.514IleAsn: 2.514 ± 0.601
2.774IlePro: 2.774 ± 0.466
2.428IleGln: 2.428 ± 0.478
3.035IleArg: 3.035 ± 0.407
2.861IleSer: 2.861 ± 0.525
2.168IleThr: 2.168 ± 0.326
2.948IleVal: 2.948 ± 0.403
0.694IleTrp: 0.694 ± 0.244
1.561IleTyr: 1.561 ± 0.336
0.0IleXaa: 0.0 ± 0.0
Lys
8.15LysAla: 8.15 ± 1.109
0.434LysCys: 0.434 ± 0.192
4.162LysAsp: 4.162 ± 0.707
3.815LysGlu: 3.815 ± 0.552
2.688LysPhe: 2.688 ± 0.604
4.769LysGly: 4.769 ± 0.732
1.474LysHis: 1.474 ± 0.352
2.254LysIle: 2.254 ± 0.483
3.381LysLys: 3.381 ± 0.606
5.115LysLeu: 5.115 ± 0.692
2.081LysMet: 2.081 ± 0.487
1.647LysAsn: 1.647 ± 0.333
2.948LysPro: 2.948 ± 0.54
2.601LysGln: 2.601 ± 0.388
3.902LysArg: 3.902 ± 0.58
2.774LysSer: 2.774 ± 0.368
3.121LysThr: 3.121 ± 0.426
4.769LysVal: 4.769 ± 0.79
0.694LysTrp: 0.694 ± 0.277
2.341LysTyr: 2.341 ± 0.358
0.0LysXaa: 0.0 ± 0.0
Leu
6.936LeuAla: 6.936 ± 0.708
0.434LeuCys: 0.434 ± 0.191
5.115LeuAsp: 5.115 ± 0.635
6.589LeuGlu: 6.589 ± 1.052
1.907LeuPhe: 1.907 ± 0.487
4.769LeuGly: 4.769 ± 0.57
0.954LeuHis: 0.954 ± 0.321
3.988LeuIle: 3.988 ± 0.505
6.589LeuLys: 6.589 ± 0.791
5.375LeuLeu: 5.375 ± 0.722
1.821LeuMet: 1.821 ± 0.388
4.075LeuAsn: 4.075 ± 0.568
2.948LeuPro: 2.948 ± 0.534
3.728LeuGln: 3.728 ± 0.551
5.029LeuArg: 5.029 ± 0.619
4.769LeuSer: 4.769 ± 0.616
5.202LeuThr: 5.202 ± 0.838
4.508LeuVal: 4.508 ± 0.793
1.301LeuTrp: 1.301 ± 0.397
1.734LeuTyr: 1.734 ± 0.361
0.0LeuXaa: 0.0 ± 0.0
Met
3.815MetAla: 3.815 ± 0.471
0.173MetCys: 0.173 ± 0.099
1.907MetAsp: 1.907 ± 0.399
1.561MetGlu: 1.561 ± 0.41
1.301MetPhe: 1.301 ± 0.301
1.474MetGly: 1.474 ± 0.368
0.434MetHis: 0.434 ± 0.202
1.127MetIle: 1.127 ± 0.339
1.474MetLys: 1.474 ± 0.358
3.035MetLeu: 3.035 ± 0.515
0.954MetMet: 0.954 ± 0.297
1.474MetAsn: 1.474 ± 0.349
1.214MetPro: 1.214 ± 0.298
1.647MetGln: 1.647 ± 0.359
1.214MetArg: 1.214 ± 0.257
1.561MetSer: 1.561 ± 0.348
1.821MetThr: 1.821 ± 0.506
2.168MetVal: 2.168 ± 0.425
0.0MetTrp: 0.0 ± 0.0
0.26MetTyr: 0.26 ± 0.134
0.0MetXaa: 0.0 ± 0.0
Asn
3.988AsnAla: 3.988 ± 0.543
0.434AsnCys: 0.434 ± 0.177
3.035AsnAsp: 3.035 ± 0.356
2.774AsnGlu: 2.774 ± 0.54
1.647AsnPhe: 1.647 ± 0.283
3.728AsnGly: 3.728 ± 0.622
0.694AsnHis: 0.694 ± 0.314
2.514AsnIle: 2.514 ± 0.443
2.341AsnLys: 2.341 ± 0.578
3.035AsnLeu: 3.035 ± 0.597
1.214AsnMet: 1.214 ± 0.308
1.647AsnAsn: 1.647 ± 0.346
2.168AsnPro: 2.168 ± 0.313
1.647AsnGln: 1.647 ± 0.309
2.514AsnArg: 2.514 ± 0.658
2.254AsnSer: 2.254 ± 0.423
2.341AsnThr: 2.341 ± 0.53
2.688AsnVal: 2.688 ± 0.414
0.434AsnTrp: 0.434 ± 0.187
1.734AsnTyr: 1.734 ± 0.492
0.0AsnXaa: 0.0 ± 0.0
Pro
4.162ProAla: 4.162 ± 0.409
0.347ProCys: 0.347 ± 0.2
2.774ProAsp: 2.774 ± 0.421
3.035ProGlu: 3.035 ± 0.558
2.168ProPhe: 2.168 ± 0.466
1.821ProGly: 1.821 ± 0.401
0.434ProHis: 0.434 ± 0.185
1.214ProIle: 1.214 ± 0.246
1.994ProLys: 1.994 ± 0.602
2.601ProLeu: 2.601 ± 0.407
0.694ProMet: 0.694 ± 0.252
2.081ProAsn: 2.081 ± 0.408
1.127ProPro: 1.127 ± 0.33
1.821ProGln: 1.821 ± 0.337
1.127ProArg: 1.127 ± 0.285
2.341ProSer: 2.341 ± 0.504
2.601ProThr: 2.601 ± 0.468
2.514ProVal: 2.514 ± 0.48
0.694ProTrp: 0.694 ± 0.164
1.214ProTyr: 1.214 ± 0.398
0.0ProXaa: 0.0 ± 0.0
Gln
5.289GlnAla: 5.289 ± 0.838
0.694GlnCys: 0.694 ± 0.303
2.774GlnAsp: 2.774 ± 0.481
3.121GlnGlu: 3.121 ± 0.452
1.561GlnPhe: 1.561 ± 0.388
3.381GlnGly: 3.381 ± 0.534
0.52GlnHis: 0.52 ± 0.22
2.341GlnIle: 2.341 ± 0.344
2.341GlnLys: 2.341 ± 0.392
4.162GlnLeu: 4.162 ± 0.71
1.301GlnMet: 1.301 ± 0.383
2.081GlnAsn: 2.081 ± 0.412
1.474GlnPro: 1.474 ± 0.35
2.341GlnGln: 2.341 ± 0.435
2.601GlnArg: 2.601 ± 0.582
2.254GlnSer: 2.254 ± 0.462
1.474GlnThr: 1.474 ± 0.356
3.208GlnVal: 3.208 ± 0.492
0.694GlnTrp: 0.694 ± 0.282
1.214GlnTyr: 1.214 ± 0.393
0.0GlnXaa: 0.0 ± 0.0
Arg
5.375ArgAla: 5.375 ± 0.799
0.694ArgCys: 0.694 ± 0.297
3.121ArgAsp: 3.121 ± 0.591
3.728ArgGlu: 3.728 ± 0.7
2.081ArgPhe: 2.081 ± 0.54
4.422ArgGly: 4.422 ± 0.466
1.04ArgHis: 1.04 ± 0.236
2.254ArgIle: 2.254 ± 0.496
3.641ArgLys: 3.641 ± 0.666
4.422ArgLeu: 4.422 ± 0.621
1.214ArgMet: 1.214 ± 0.266
2.514ArgAsn: 2.514 ± 0.56
1.647ArgPro: 1.647 ± 0.453
2.601ArgGln: 2.601 ± 0.524
2.254ArgArg: 2.254 ± 0.462
3.121ArgSer: 3.121 ± 0.5
3.035ArgThr: 3.035 ± 0.374
4.162ArgVal: 4.162 ± 0.538
0.694ArgTrp: 0.694 ± 0.238
1.734ArgTyr: 1.734 ± 0.579
0.0ArgXaa: 0.0 ± 0.0
Ser
6.156SerAla: 6.156 ± 0.458
0.434SerCys: 0.434 ± 0.185
3.728SerAsp: 3.728 ± 0.71
3.381SerGlu: 3.381 ± 0.51
2.341SerPhe: 2.341 ± 0.365
5.462SerGly: 5.462 ± 0.856
1.214SerHis: 1.214 ± 0.327
3.641SerIle: 3.641 ± 0.924
2.948SerLys: 2.948 ± 0.465
3.295SerLeu: 3.295 ± 0.352
1.214SerMet: 1.214 ± 0.4
2.168SerAsn: 2.168 ± 0.417
2.081SerPro: 2.081 ± 0.345
1.994SerGln: 1.994 ± 0.398
3.035SerArg: 3.035 ± 0.418
2.774SerSer: 2.774 ± 0.533
3.555SerThr: 3.555 ± 0.715
3.902SerVal: 3.902 ± 0.481
1.04SerTrp: 1.04 ± 0.264
2.774SerTyr: 2.774 ± 0.424
0.0SerXaa: 0.0 ± 0.0
Thr
5.115ThrAla: 5.115 ± 0.776
0.52ThrCys: 0.52 ± 0.251
4.075ThrAsp: 4.075 ± 0.647
3.728ThrGlu: 3.728 ± 0.407
2.081ThrPhe: 2.081 ± 0.372
4.942ThrGly: 4.942 ± 0.482
1.214ThrHis: 1.214 ± 0.295
2.948ThrIle: 2.948 ± 0.478
3.641ThrLys: 3.641 ± 0.602
4.769ThrLeu: 4.769 ± 0.832
0.867ThrMet: 0.867 ± 0.278
2.601ThrAsn: 2.601 ± 0.505
2.514ThrPro: 2.514 ± 0.361
2.341ThrGln: 2.341 ± 0.538
2.948ThrArg: 2.948 ± 0.489
3.035ThrSer: 3.035 ± 0.697
2.774ThrThr: 2.774 ± 0.624
3.641ThrVal: 3.641 ± 0.549
0.78ThrTrp: 0.78 ± 0.257
1.127ThrTyr: 1.127 ± 0.27
0.0ThrXaa: 0.0 ± 0.0
Val
6.156ValAla: 6.156 ± 0.638
0.434ValCys: 0.434 ± 0.181
3.728ValAsp: 3.728 ± 0.471
4.595ValGlu: 4.595 ± 0.713
1.994ValPhe: 1.994 ± 0.767
4.942ValGly: 4.942 ± 0.948
1.214ValHis: 1.214 ± 0.335
3.641ValIle: 3.641 ± 0.556
3.815ValLys: 3.815 ± 0.547
5.115ValLeu: 5.115 ± 0.654
1.994ValMet: 1.994 ± 0.427
3.295ValAsn: 3.295 ± 0.499
2.601ValPro: 2.601 ± 0.563
2.601ValGln: 2.601 ± 0.432
3.815ValArg: 3.815 ± 0.474
3.815ValSer: 3.815 ± 0.486
4.595ValThr: 4.595 ± 0.675
5.289ValVal: 5.289 ± 0.622
1.04ValTrp: 1.04 ± 0.229
1.821ValTyr: 1.821 ± 0.508
0.0ValXaa: 0.0 ± 0.0
Trp
0.867TrpAla: 0.867 ± 0.253
0.434TrpCys: 0.434 ± 0.187
0.867TrpAsp: 0.867 ± 0.34
0.52TrpGlu: 0.52 ± 0.237
0.694TrpPhe: 0.694 ± 0.196
0.867TrpGly: 0.867 ± 0.297
0.434TrpHis: 0.434 ± 0.176
0.52TrpIle: 0.52 ± 0.242
1.214TrpLys: 1.214 ± 0.369
1.127TrpLeu: 1.127 ± 0.313
0.26TrpMet: 0.26 ± 0.128
1.127TrpAsn: 1.127 ± 0.272
0.087TrpPro: 0.087 ± 0.093
0.694TrpGln: 0.694 ± 0.191
0.867TrpArg: 0.867 ± 0.28
0.954TrpSer: 0.954 ± 0.361
0.867TrpThr: 0.867 ± 0.297
1.561TrpVal: 1.561 ± 0.691
0.26TrpTrp: 0.26 ± 0.192
0.173TrpTyr: 0.173 ± 0.116
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.948TyrAla: 2.948 ± 0.435
0.173TyrCys: 0.173 ± 0.138
2.514TyrAsp: 2.514 ± 0.63
1.907TyrGlu: 1.907 ± 0.426
0.607TyrPhe: 0.607 ± 0.22
3.121TyrGly: 3.121 ± 0.556
0.434TyrHis: 0.434 ± 0.228
1.647TyrIle: 1.647 ± 0.4
1.647TyrLys: 1.647 ± 0.3
1.994TyrLeu: 1.994 ± 0.47
1.04TyrMet: 1.04 ± 0.217
1.214TyrAsn: 1.214 ± 0.276
1.127TyrPro: 1.127 ± 0.345
1.387TyrGln: 1.387 ± 0.291
2.254TyrArg: 2.254 ± 0.354
1.214TyrSer: 1.214 ± 0.434
2.861TyrThr: 2.861 ± 0.636
1.907TyrVal: 1.907 ± 0.48
0.607TyrTrp: 0.607 ± 0.205
0.954TyrTyr: 0.954 ± 0.333
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 42 proteins (11535 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski