Amino acid dipepetide frequency for Circovirus-like genome DCCV-9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.03AlaAla: 3.03 ± 0.884
0.0AlaCys: 0.0 ± 0.0
6.061AlaAsp: 6.061 ± 1.167
1.515AlaGlu: 1.515 ± 1.17
0.0AlaPhe: 0.0 ± 0.0
3.03AlaGly: 3.03 ± 2.051
0.0AlaHis: 0.0 ± 0.0
3.03AlaIle: 3.03 ± 2.387
4.545AlaLys: 4.545 ± 1.844
0.0AlaLeu: 0.0 ± 0.0
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
1.515AlaPro: 1.515 ± 1.17
0.0AlaGln: 0.0 ± 0.0
7.576AlaArg: 7.576 ± 1.017
3.03AlaSer: 3.03 ± 2.339
6.061AlaThr: 6.061 ± 4.007
3.03AlaVal: 3.03 ± 0.884
3.03AlaTrp: 3.03 ± 1.898
7.576AlaTyr: 7.576 ± 4.104
0.0AlaXaa: 0.0 ± 0.0
Cys
1.515CysAla: 1.515 ± 1.17
0.0CysCys: 0.0 ± 0.0
1.515CysAsp: 1.515 ± 0.949
1.515CysGlu: 1.515 ± 0.949
1.515CysPhe: 1.515 ± 2.406
4.545CysGly: 4.545 ± 1.413
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
3.03CysLeu: 3.03 ± 0.884
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.515CysPro: 1.515 ± 0.949
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.03CysSer: 3.03 ± 2.051
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.515CysTrp: 1.515 ± 0.949
1.515CysTyr: 1.515 ± 0.949
0.0CysXaa: 0.0 ± 0.0
Asp
3.03AspAla: 3.03 ± 2.387
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
6.061AspGlu: 6.061 ± 3.796
4.545AspPhe: 4.545 ± 1.413
3.03AspGly: 3.03 ± 1.898
0.0AspHis: 0.0 ± 0.0
3.03AspIle: 3.03 ± 0.884
1.515AspLys: 1.515 ± 2.406
3.03AspLeu: 3.03 ± 1.898
3.03AspMet: 3.03 ± 1.666
1.515AspAsn: 1.515 ± 1.17
1.515AspPro: 1.515 ± 1.17
3.03AspGln: 3.03 ± 2.051
4.545AspArg: 4.545 ± 1.413
9.091AspSer: 9.091 ± 3.243
3.03AspThr: 3.03 ± 1.898
4.545AspVal: 4.545 ± 1.413
1.515AspTrp: 1.515 ± 0.949
7.576AspTyr: 7.576 ± 3.135
0.0AspXaa: 0.0 ± 0.0
Glu
1.515GluAla: 1.515 ± 0.949
0.0GluCys: 0.0 ± 0.0
4.545GluAsp: 4.545 ± 2.103
3.03GluGlu: 3.03 ± 2.051
1.515GluPhe: 1.515 ± 0.949
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
1.515GluLys: 1.515 ± 0.949
4.545GluLeu: 4.545 ± 1.622
0.0GluMet: 0.0 ± 0.0
3.03GluAsn: 3.03 ± 1.898
3.03GluPro: 3.03 ± 1.898
0.0GluGln: 0.0 ± 0.0
3.03GluArg: 3.03 ± 0.884
4.545GluSer: 4.545 ± 2.103
10.606GluThr: 10.606 ± 2.931
4.545GluVal: 4.545 ± 1.413
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.515PheAla: 1.515 ± 1.17
0.0PheCys: 0.0 ± 0.0
3.03PheAsp: 3.03 ± 1.898
0.0PheGlu: 0.0 ± 0.0
1.515PhePhe: 1.515 ± 2.406
1.515PheGly: 1.515 ± 1.17
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
4.545PheLys: 4.545 ± 1.622
1.515PheLeu: 1.515 ± 0.949
3.03PheMet: 3.03 ± 0.884
3.03PheAsn: 3.03 ± 1.898
0.0PhePro: 0.0 ± 0.0
3.03PheGln: 3.03 ± 1.898
3.03PheArg: 3.03 ± 2.051
3.03PheSer: 3.03 ± 2.051
1.515PheThr: 1.515 ± 1.17
4.545PheVal: 4.545 ± 1.622
1.515PheTrp: 1.515 ± 1.17
1.515PheTyr: 1.515 ± 1.17
0.0PheXaa: 0.0 ± 0.0
Gly
1.515GlyAla: 1.515 ± 0.949
1.515GlyCys: 1.515 ± 0.949
6.061GlyAsp: 6.061 ± 2.239
1.515GlyGlu: 1.515 ± 0.949
1.515GlyPhe: 1.515 ± 0.949
1.515GlyGly: 1.515 ± 0.949
0.0GlyHis: 0.0 ± 0.0
1.515GlyIle: 1.515 ± 1.17
6.061GlyLys: 6.061 ± 2.239
4.545GlyLeu: 4.545 ± 4.369
0.0GlyMet: 0.0 ± 0.0
3.03GlyAsn: 3.03 ± 2.339
3.03GlyPro: 3.03 ± 2.339
4.545GlyGln: 4.545 ± 1.413
4.545GlyArg: 4.545 ± 2.847
7.576GlySer: 7.576 ± 1.017
7.576GlyThr: 7.576 ± 2.772
1.515GlyVal: 1.515 ± 0.949
0.0GlyTrp: 0.0 ± 0.0
4.545GlyTyr: 4.545 ± 1.844
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.515HisCys: 1.515 ± 0.949
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.515HisPhe: 1.515 ± 0.949
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
3.03HisLeu: 3.03 ± 0.884
0.0HisMet: 0.0 ± 0.0
3.03HisAsn: 3.03 ± 2.339
1.515HisPro: 1.515 ± 0.949
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
3.03HisThr: 3.03 ± 2.387
1.515HisVal: 1.515 ± 1.17
1.515HisTrp: 1.515 ± 0.949
1.515HisTyr: 1.515 ± 0.949
0.0HisXaa: 0.0 ± 0.0
Ile
3.03IleAla: 3.03 ± 2.387
0.0IleCys: 0.0 ± 0.0
1.515IleAsp: 1.515 ± 0.949
0.0IleGlu: 0.0 ± 0.0
1.515IlePhe: 1.515 ± 2.406
7.576IleGly: 7.576 ± 3.135
0.0IleHis: 0.0 ± 0.0
3.03IleIle: 3.03 ± 0.884
3.03IleLys: 3.03 ± 2.339
7.576IleLeu: 7.576 ± 9.389
3.03IleMet: 3.03 ± 2.051
3.03IleAsn: 3.03 ± 2.339
1.515IlePro: 1.515 ± 1.17
1.515IleGln: 1.515 ± 0.949
0.0IleArg: 0.0 ± 0.0
0.0IleSer: 0.0 ± 0.0
3.03IleThr: 3.03 ± 2.387
3.03IleVal: 3.03 ± 2.051
0.0IleTrp: 0.0 ± 0.0
3.03IleTyr: 3.03 ± 1.898
0.0IleXaa: 0.0 ± 0.0
Lys
9.091LysAla: 9.091 ± 5.261
1.515LysCys: 1.515 ± 0.949
0.0LysAsp: 0.0 ± 0.0
3.03LysGlu: 3.03 ± 2.051
3.03LysPhe: 3.03 ± 2.339
6.061LysGly: 6.061 ± 1.768
1.515LysHis: 1.515 ± 0.949
3.03LysIle: 3.03 ± 0.884
6.061LysLys: 6.061 ± 3.705
3.03LysLeu: 3.03 ± 2.339
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
3.03LysPro: 3.03 ± 1.898
3.03LysGln: 3.03 ± 0.884
7.576LysArg: 7.576 ± 3.204
7.576LysSer: 7.576 ± 2.772
4.545LysThr: 4.545 ± 1.844
3.03LysVal: 3.03 ± 0.884
1.515LysTrp: 1.515 ± 0.949
4.545LysTyr: 4.545 ± 2.847
0.0LysXaa: 0.0 ± 0.0
Leu
7.576LeuAla: 7.576 ± 1.017
1.515LeuCys: 1.515 ± 1.17
7.576LeuAsp: 7.576 ± 3.507
4.545LeuGlu: 4.545 ± 1.622
3.03LeuPhe: 3.03 ± 2.051
6.061LeuGly: 6.061 ± 2.538
1.515LeuHis: 1.515 ± 1.17
6.061LeuIle: 6.061 ± 6.749
3.03LeuLys: 3.03 ± 1.898
4.545LeuLeu: 4.545 ± 1.844
4.545LeuMet: 4.545 ± 1.622
3.03LeuAsn: 3.03 ± 2.339
6.061LeuPro: 6.061 ± 4.101
0.0LeuGln: 0.0 ± 0.0
3.03LeuArg: 3.03 ± 0.884
9.091LeuSer: 9.091 ± 3.217
3.03LeuThr: 3.03 ± 1.898
4.545LeuVal: 4.545 ± 1.413
1.515LeuTrp: 1.515 ± 0.949
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.03MetAla: 3.03 ± 2.051
1.515MetCys: 1.515 ± 1.17
1.515MetAsp: 1.515 ± 0.949
1.515MetGlu: 1.515 ± 0.949
1.515MetPhe: 1.515 ± 2.406
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
3.03MetLys: 3.03 ± 0.884
6.061MetLeu: 6.061 ± 2.538
1.515MetMet: 1.515 ± 2.406
1.515MetAsn: 1.515 ± 1.17
1.515MetPro: 1.515 ± 1.17
1.515MetGln: 1.515 ± 0.949
1.515MetArg: 1.515 ± 0.949
1.515MetSer: 1.515 ± 2.406
0.0MetThr: 0.0 ± 0.0
1.515MetVal: 1.515 ± 1.17
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.515AsnAla: 1.515 ± 1.17
1.515AsnCys: 1.515 ± 1.17
1.515AsnAsp: 1.515 ± 1.17
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
1.515AsnGly: 1.515 ± 1.17
1.515AsnHis: 1.515 ± 1.17
1.515AsnIle: 1.515 ± 1.17
1.515AsnLys: 1.515 ± 0.949
0.0AsnLeu: 0.0 ± 0.0
1.515AsnMet: 1.515 ± 0.949
1.515AsnAsn: 1.515 ± 0.949
3.03AsnPro: 3.03 ± 0.884
3.03AsnGln: 3.03 ± 0.884
1.515AsnArg: 1.515 ± 0.949
0.0AsnSer: 0.0 ± 0.0
3.03AsnThr: 3.03 ± 2.339
4.545AsnVal: 4.545 ± 1.844
1.515AsnTrp: 1.515 ± 0.949
3.03AsnTyr: 3.03 ± 0.884
0.0AsnXaa: 0.0 ± 0.0
Pro
1.515ProAla: 1.515 ± 0.949
0.0ProCys: 0.0 ± 0.0
6.061ProAsp: 6.061 ± 2.538
3.03ProGlu: 3.03 ± 0.884
0.0ProPhe: 0.0 ± 0.0
3.03ProGly: 3.03 ± 0.884
1.515ProHis: 1.515 ± 0.949
0.0ProIle: 0.0 ± 0.0
4.545ProLys: 4.545 ± 1.413
1.515ProLeu: 1.515 ± 2.406
3.03ProMet: 3.03 ± 1.606
1.515ProAsn: 1.515 ± 1.17
3.03ProPro: 3.03 ± 2.387
1.515ProGln: 1.515 ± 1.17
1.515ProArg: 1.515 ± 1.17
1.515ProSer: 1.515 ± 2.406
1.515ProThr: 1.515 ± 1.17
4.545ProVal: 4.545 ± 2.847
3.03ProTrp: 3.03 ± 0.884
6.061ProTyr: 6.061 ± 1.768
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.515GlnCys: 1.515 ± 0.949
1.515GlnAsp: 1.515 ± 1.17
3.03GlnGlu: 3.03 ± 2.051
1.515GlnPhe: 1.515 ± 0.949
3.03GlnGly: 3.03 ± 0.884
0.0GlnHis: 0.0 ± 0.0
1.515GlnIle: 1.515 ± 0.949
4.545GlnLys: 4.545 ± 1.413
3.03GlnLeu: 3.03 ± 0.884
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.515GlnPro: 1.515 ± 0.949
1.515GlnGln: 1.515 ± 0.949
1.515GlnArg: 1.515 ± 0.949
3.03GlnSer: 3.03 ± 2.051
0.0GlnThr: 0.0 ± 0.0
4.545GlnVal: 4.545 ± 1.413
3.03GlnTrp: 3.03 ± 2.339
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.515ArgAla: 1.515 ± 1.17
4.545ArgCys: 4.545 ± 2.103
3.03ArgAsp: 3.03 ± 0.884
3.03ArgGlu: 3.03 ± 0.884
3.03ArgPhe: 3.03 ± 1.898
1.515ArgGly: 1.515 ± 0.949
0.0ArgHis: 0.0 ± 0.0
6.061ArgIle: 6.061 ± 1.167
1.515ArgLys: 1.515 ± 0.949
9.091ArgLeu: 9.091 ± 2.826
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
4.545ArgPro: 4.545 ± 3.509
3.03ArgGln: 3.03 ± 1.898
9.091ArgArg: 9.091 ± 2.826
6.061ArgSer: 6.061 ± 4.101
4.545ArgThr: 4.545 ± 2.103
1.515ArgVal: 1.515 ± 1.17
0.0ArgTrp: 0.0 ± 0.0
3.03ArgTyr: 3.03 ± 1.898
0.0ArgXaa: 0.0 ± 0.0
Ser
3.03SerAla: 3.03 ± 2.339
0.0SerCys: 0.0 ± 0.0
1.515SerAsp: 1.515 ± 1.17
3.03SerGlu: 3.03 ± 1.898
0.0SerPhe: 0.0 ± 0.0
7.576SerGly: 7.576 ± 3.969
3.03SerHis: 3.03 ± 0.884
7.576SerIle: 7.576 ± 6.407
6.061SerLys: 6.061 ± 1.947
9.091SerLeu: 9.091 ± 3.217
3.03SerMet: 3.03 ± 2.051
0.0SerAsn: 0.0 ± 0.0
4.545SerPro: 4.545 ± 2.103
1.515SerGln: 1.515 ± 0.949
9.091SerArg: 9.091 ± 0.283
3.03SerSer: 3.03 ± 4.812
4.545SerThr: 4.545 ± 7.217
1.515SerVal: 1.515 ± 0.949
1.515SerTrp: 1.515 ± 0.949
1.515SerTyr: 1.515 ± 1.17
0.0SerXaa: 0.0 ± 0.0
Thr
4.545ThrAla: 4.545 ± 4.369
1.515ThrCys: 1.515 ± 2.406
7.576ThrAsp: 7.576 ± 2.158
3.03ThrGlu: 3.03 ± 2.051
6.061ThrPhe: 6.061 ± 4.679
3.03ThrGly: 3.03 ± 2.339
4.545ThrHis: 4.545 ± 1.622
0.0ThrIle: 0.0 ± 0.0
9.091ThrLys: 9.091 ± 2.653
7.576ThrLeu: 7.576 ± 3.969
1.515ThrMet: 1.515 ± 1.872
3.03ThrAsn: 3.03 ± 0.884
1.515ThrPro: 1.515 ± 0.949
3.03ThrGln: 3.03 ± 2.387
1.515ThrArg: 1.515 ± 1.17
4.545ThrSer: 4.545 ± 1.413
0.0ThrThr: 0.0 ± 0.0
6.061ThrVal: 6.061 ± 1.167
3.03ThrTrp: 3.03 ± 0.884
3.03ThrTyr: 3.03 ± 0.884
0.0ThrXaa: 0.0 ± 0.0
Val
3.03ValAla: 3.03 ± 1.898
0.0ValCys: 0.0 ± 0.0
6.061ValAsp: 6.061 ± 3.796
6.061ValGlu: 6.061 ± 1.768
1.515ValPhe: 1.515 ± 0.949
1.515ValGly: 1.515 ± 0.949
3.03ValHis: 3.03 ± 0.884
1.515ValIle: 1.515 ± 2.406
7.576ValLys: 7.576 ± 2.645
4.545ValLeu: 4.545 ± 2.103
1.515ValMet: 1.515 ± 1.17
3.03ValAsn: 3.03 ± 1.898
6.061ValPro: 6.061 ± 1.768
3.03ValGln: 3.03 ± 2.339
3.03ValArg: 3.03 ± 2.051
0.0ValSer: 0.0 ± 0.0
12.121ValThr: 12.121 ± 3.537
4.545ValVal: 4.545 ± 3.509
0.0ValTrp: 0.0 ± 0.0
1.515ValTyr: 1.515 ± 0.949
0.0ValXaa: 0.0 ± 0.0
Trp
1.515TrpAla: 1.515 ± 0.949
1.515TrpCys: 1.515 ± 0.949
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
3.03TrpPhe: 3.03 ± 0.884
1.515TrpGly: 1.515 ± 1.17
1.515TrpHis: 1.515 ± 0.949
4.545TrpIle: 4.545 ± 1.413
1.515TrpLys: 1.515 ± 1.17
0.0TrpLeu: 0.0 ± 0.0
1.515TrpMet: 1.515 ± 0.949
1.515TrpAsn: 1.515 ± 0.949
1.515TrpPro: 1.515 ± 0.949
0.0TrpGln: 0.0 ± 0.0
1.515TrpArg: 1.515 ± 0.949
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
3.03TrpVal: 3.03 ± 0.884
1.515TrpTrp: 1.515 ± 1.17
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.515TyrAla: 1.515 ± 1.17
3.03TyrCys: 3.03 ± 1.898
4.545TyrAsp: 4.545 ± 1.413
1.515TyrGlu: 1.515 ± 1.17
1.515TyrPhe: 1.515 ± 0.949
6.061TyrGly: 6.061 ± 1.768
0.0TyrHis: 0.0 ± 0.0
3.03TyrIle: 3.03 ± 0.884
1.515TyrLys: 1.515 ± 1.17
4.545TyrLeu: 4.545 ± 2.847
0.0TyrMet: 0.0 ± 0.0
1.515TyrAsn: 1.515 ± 1.17
0.0TyrPro: 0.0 ± 0.0
1.515TyrGln: 1.515 ± 0.949
1.515TyrArg: 1.515 ± 1.17
4.545TyrSer: 4.545 ± 1.844
6.061TyrThr: 6.061 ± 2.239
7.576TyrVal: 7.576 ± 3.135
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (661 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski