Amino acid dipepetide frequency for Paraburkholderia caballeronis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.94AlaAla: 19.94 ± 0.148	1.307AlaCys: 1.307 ± 0.023	7.476AlaAsp: 7.476 ± 0.075	5.664AlaGlu: 5.664 ± 0.06	4.511AlaPhe: 4.511 ± 0.052	11.528AlaGly: 11.528 ± 0.108	3.011AlaHis: 3.011 ± 0.041	5.736AlaIle: 5.736 ± 0.063	3.391AlaLys: 3.391 ± 0.05	14.937AlaLeu: 14.937 ± 0.121	3.151AlaMet: 3.151 ± 0.04	3.389AlaAsn: 3.389 ± 0.047	6.433AlaPro: 6.433 ± 0.073	5.614AlaGln: 5.614 ± 0.068	10.018AlaArg: 10.018 ± 0.1	7.719AlaSer: 7.719 ± 0.072	6.768AlaThr: 6.768 ± 0.072	9.01AlaVal: 9.01 ± 0.064	1.85AlaTrp: 1.85 ± 0.034	2.683AlaTyr: 2.683 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.272CysAla: 1.272 ± 0.025	0.129CysCys: 0.129 ± 0.008	0.56CysAsp: 0.56 ± 0.017	0.482CysGlu: 0.482 ± 0.016	0.309CysPhe: 0.309 ± 0.011	1.026CysGly: 1.026 ± 0.024	0.232CysHis: 0.232 ± 0.011	0.367CysIle: 0.367 ± 0.016	0.168CysLys: 0.168 ± 0.009	0.686CysLeu: 0.686 ± 0.018	0.189CysMet: 0.189 ± 0.009	0.226CysAsn: 0.226 ± 0.011	0.429CysPro: 0.429 ± 0.016	0.198CysGln: 0.198 ± 0.011	0.646CysArg: 0.646 ± 0.018	0.466CysSer: 0.466 ± 0.015	0.448CysThr: 0.448 ± 0.017	0.83CysVal: 0.83 ± 0.019	0.102CysTrp: 0.102 ± 0.008	0.216CysTyr: 0.216 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	9.535AspAla: 9.535 ± 0.101	0.466AspCys: 0.466 ± 0.015	3.897AspAsp: 3.897 ± 0.047	3.539AspGlu: 3.539 ± 0.045	1.903AspPhe: 1.903 ± 0.033	5.304AspGly: 5.304 ± 0.063	1.186AspHis: 1.186 ± 0.025	2.259AspIle: 2.259 ± 0.04	1.202AspLys: 1.202 ± 0.028	5.295AspLeu: 5.295 ± 0.056	1.071AspMet: 1.071 ± 0.025	1.296AspAsn: 1.296 ± 0.031	3.164AspPro: 3.164 ± 0.041	1.516AspGln: 1.516 ± 0.03	3.712AspArg: 3.712 ± 0.037	2.434AspSer: 2.434 ± 0.043	3.006AspThr: 3.006 ± 0.041	4.848AspVal: 4.848 ± 0.046	0.92AspTrp: 0.92 ± 0.023	1.554AspTyr: 1.554 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	5.936GluAla: 5.936 ± 0.069	0.387GluCys: 0.387 ± 0.016	1.824GluAsp: 1.824 ± 0.031	2.042GluGlu: 2.042 ± 0.041	1.668GluPhe: 1.668 ± 0.029	3.1GluGly: 3.1 ± 0.042	1.383GluHis: 1.383 ± 0.026	2.606GluIle: 2.606 ± 0.042	1.47GluLys: 1.47 ± 0.031	5.212GluLeu: 5.212 ± 0.063	1.08GluMet: 1.08 ± 0.026	1.291GluAsn: 1.291 ± 0.024	2.733GluPro: 2.733 ± 0.045	2.213GluGln: 2.213 ± 0.038	5.052GluArg: 5.052 ± 0.058	2.359GluSer: 2.359 ± 0.037	2.802GluThr: 2.802 ± 0.043	3.236GluVal: 3.236 ± 0.049	0.676GluTrp: 0.676 ± 0.019	1.06GluTyr: 1.06 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.924PheAla: 4.924 ± 0.054	0.388PheCys: 0.388 ± 0.012	2.905PheAsp: 2.905 ± 0.039	1.924PheGlu: 1.924 ± 0.033	1.37PhePhe: 1.37 ± 0.033	3.778PheGly: 3.778 ± 0.048	0.721PheHis: 0.721 ± 0.02	1.429PheIle: 1.429 ± 0.024	0.742PheLys: 0.742 ± 0.02	2.789PheLeu: 2.789 ± 0.042	0.725PheMet: 0.725 ± 0.019	1.032PheAsn: 1.032 ± 0.023	1.538PhePro: 1.538 ± 0.029	0.952PheGln: 0.952 ± 0.023	2.133PheArg: 2.133 ± 0.035	2.163PheSer: 2.163 ± 0.038	1.891PheThr: 1.891 ± 0.033	3.404PheVal: 3.404 ± 0.04	0.502PheTrp: 0.502 ± 0.017	0.9PheTyr: 0.9 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.372GlyAla: 10.372 ± 0.113	0.853GlyCys: 0.853 ± 0.021	4.495GlyAsp: 4.495 ± 0.052	4.15GlyGlu: 4.15 ± 0.055	3.489GlyPhe: 3.489 ± 0.041	7.387GlyGly: 7.387 ± 0.112	1.927GlyHis: 1.927 ± 0.033	4.307GlyIle: 4.307 ± 0.054	2.673GlyLys: 2.673 ± 0.039	8.133GlyLeu: 8.133 ± 0.066	2.033GlyMet: 2.033 ± 0.034	2.375GlyAsn: 2.375 ± 0.057	3.224GlyPro: 3.224 ± 0.044	2.675GlyGln: 2.675 ± 0.036	5.878GlyArg: 5.878 ± 0.063	4.792GlySer: 4.792 ± 0.088	4.718GlyThr: 4.718 ± 0.135	6.928GlyVal: 6.928 ± 0.067	1.389GlyTrp: 1.389 ± 0.028	2.491GlyTyr: 2.491 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	3.401HisAla: 3.401 ± 0.045	0.265HisCys: 0.265 ± 0.011	1.466HisAsp: 1.466 ± 0.028	1.146HisGlu: 1.146 ± 0.026	0.891HisPhe: 0.891 ± 0.021	2.306HisGly: 2.306 ± 0.034	0.629HisHis: 0.629 ± 0.02	0.776HisIle: 0.776 ± 0.021	0.408HisLys: 0.408 ± 0.015	2.083HisLeu: 2.083 ± 0.035	0.406HisMet: 0.406 ± 0.015	0.525HisAsn: 0.525 ± 0.015	1.494HisPro: 1.494 ± 0.024	0.604HisGln: 0.604 ± 0.018	1.658HisArg: 1.658 ± 0.03	0.98HisSer: 0.98 ± 0.025	1.061HisThr: 1.061 ± 0.024	1.739HisVal: 1.739 ± 0.029	0.402HisTrp: 0.402 ± 0.014	0.68HisTyr: 0.68 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	7.064IleAla: 7.064 ± 0.075	0.392IleCys: 0.392 ± 0.013	3.588IleAsp: 3.588 ± 0.046	3.068IleGlu: 3.068 ± 0.041	1.284IlePhe: 1.284 ± 0.027	4.779IleGly: 4.779 ± 0.06	0.838IleHis: 0.838 ± 0.023	1.298IleIle: 1.298 ± 0.035	1.024IleLys: 1.024 ± 0.024	2.981IleLeu: 2.981 ± 0.046	0.628IleMet: 0.628 ± 0.018	1.211IleAsn: 1.211 ± 0.027	1.949IlePro: 1.949 ± 0.034	1.13IleGln: 1.13 ± 0.025	2.82IleArg: 2.82 ± 0.04	2.195IleSer: 2.195 ± 0.038	2.189IleThr: 2.189 ± 0.042	4.488IleVal: 4.488 ± 0.058	0.451IleTrp: 0.451 ± 0.015	0.862IleTyr: 0.862 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.011LysAla: 3.011 ± 0.047	0.127LysCys: 0.127 ± 0.008	1.279LysAsp: 1.279 ± 0.028	1.168LysGlu: 1.168 ± 0.026	0.745LysPhe: 0.745 ± 0.022	1.828LysGly: 1.828 ± 0.032	0.558LysHis: 0.558 ± 0.017	1.313LysIle: 1.313 ± 0.027	0.993LysLys: 0.993 ± 0.033	2.917LysLeu: 2.917 ± 0.048	0.626LysMet: 0.626 ± 0.017	0.724LysAsn: 0.724 ± 0.02	1.818LysPro: 1.818 ± 0.033	1.067LysGln: 1.067 ± 0.025	2.104LysArg: 2.104 ± 0.034	1.406LysSer: 1.406 ± 0.028	1.63LysThr: 1.63 ± 0.031	1.963LysVal: 1.963 ± 0.038	0.328LysTrp: 0.328 ± 0.013	0.584LysTyr: 0.584 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	14.716LeuAla: 14.716 ± 0.107	1.008LeuCys: 1.008 ± 0.022	6.575LeuAsp: 6.575 ± 0.064	4.539LeuGlu: 4.539 ± 0.061	3.588LeuPhe: 3.588 ± 0.049	8.092LeuGly: 8.092 ± 0.08	2.304LeuHis: 2.304 ± 0.037	4.392LeuIle: 4.392 ± 0.052	3.019LeuLys: 3.019 ± 0.042	9.983LeuLeu: 9.983 ± 0.098	2.083LeuMet: 2.083 ± 0.035	2.725LeuAsn: 2.725 ± 0.044	5.904LeuPro: 5.904 ± 0.069	3.123LeuGln: 3.123 ± 0.038	7.456LeuArg: 7.456 ± 0.071	5.958LeuSer: 5.958 ± 0.074	5.55LeuThr: 5.55 ± 0.061	7.5LeuVal: 7.5 ± 0.071	1.135LeuTrp: 1.135 ± 0.025	2.257LeuTyr: 2.257 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	2.22MetAla: 2.22 ± 0.03	0.15MetCys: 0.15 ± 0.008	0.9MetAsp: 0.9 ± 0.021	0.823MetGlu: 0.823 ± 0.021	0.706MetPhe: 0.706 ± 0.02	1.383MetGly: 1.383 ± 0.031	0.511MetHis: 0.511 ± 0.018	1.055MetIle: 1.055 ± 0.023	0.896MetLys: 0.896 ± 0.021	2.506MetLeu: 2.506 ± 0.039	0.535MetMet: 0.535 ± 0.017	0.888MetAsn: 0.888 ± 0.021	1.375MetPro: 1.375 ± 0.026	0.975MetGln: 0.975 ± 0.021	1.711MetArg: 1.711 ± 0.03	1.59MetSer: 1.59 ± 0.03	1.592MetThr: 1.592 ± 0.03	1.382MetVal: 1.382 ± 0.03	0.191MetTrp: 0.191 ± 0.008	0.382MetTyr: 0.382 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.712AsnAla: 3.712 ± 0.056	0.219AsnCys: 0.219 ± 0.011	1.522AsnAsp: 1.522 ± 0.03	1.228AsnGlu: 1.228 ± 0.027	0.926AsnPhe: 0.926 ± 0.019	2.685AsnGly: 2.685 ± 0.06	0.537AsnHis: 0.537 ± 0.019	1.051AsnIle: 1.051 ± 0.026	0.521AsnLys: 0.521 ± 0.016	2.652AsnLeu: 2.652 ± 0.04	0.483AsnMet: 0.483 ± 0.018	0.769AsnAsn: 0.769 ± 0.025	1.801AsnPro: 1.801 ± 0.038	0.856AsnGln: 0.856 ± 0.02	1.847AsnArg: 1.847 ± 0.031	1.239AsnSer: 1.239 ± 0.035	1.425AsnThr: 1.425 ± 0.039	2.287AsnVal: 2.287 ± 0.039	0.388AsnTrp: 0.388 ± 0.018	0.66AsnTyr: 0.66 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	7.363ProAla: 7.363 ± 0.084	0.344ProCys: 0.344 ± 0.015	3.785ProAsp: 3.785 ± 0.05	2.745ProGlu: 2.745 ± 0.041	1.967ProPhe: 1.967 ± 0.035	4.392ProGly: 4.392 ± 0.05	1.335ProHis: 1.335 ± 0.024	1.791ProIle: 1.791 ± 0.032	1.317ProLys: 1.317 ± 0.029	5.473ProLeu: 5.473 ± 0.062	1.05ProMet: 1.05 ± 0.02	1.296ProAsn: 1.296 ± 0.026	2.798ProPro: 2.798 ± 0.052	2.023ProGln: 2.023 ± 0.035	3.2ProArg: 3.2 ± 0.044	2.829ProSer: 2.829 ± 0.038	2.56ProThr: 2.56 ± 0.05	4.546ProVal: 4.546 ± 0.052	0.7ProTrp: 0.7 ± 0.019	1.281ProTyr: 1.281 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.06GlnAla: 4.06 ± 0.052	0.271GlnCys: 0.271 ± 0.011	1.283GlnAsp: 1.283 ± 0.025	1.142GlnGlu: 1.142 ± 0.026	1.262GlnPhe: 1.262 ± 0.025	2.252GlnGly: 2.252 ± 0.036	0.92GlnHis: 0.92 ± 0.02	1.939GlnIle: 1.939 ± 0.034	1.006GlnLys: 1.006 ± 0.027	3.752GlnLeu: 3.752 ± 0.045	1.007GlnMet: 1.007 ± 0.021	0.917GlnAsn: 0.917 ± 0.023	2.208GlnPro: 2.208 ± 0.041	2.011GlnGln: 2.011 ± 0.04	3.04GlnArg: 3.04 ± 0.042	1.936GlnSer: 1.936 ± 0.035	2.081GlnThr: 2.081 ± 0.038	2.419GlnVal: 2.419 ± 0.043	0.564GlnTrp: 0.564 ± 0.02	0.929GlnTyr: 0.929 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	9.159ArgAla: 9.159 ± 0.081	0.621ArgCys: 0.621 ± 0.018	4.456ArgAsp: 4.456 ± 0.051	4.281ArgGlu: 4.281 ± 0.049	3.161ArgPhe: 3.161 ± 0.044	5.033ArgGly: 5.033 ± 0.057	2.013ArgHis: 2.013 ± 0.035	3.807ArgIle: 3.807 ± 0.05	1.761ArgLys: 1.761 ± 0.034	7.549ArgLeu: 7.549 ± 0.076	1.857ArgMet: 1.857 ± 0.031	1.884ArgAsn: 1.884 ± 0.029	3.365ArgPro: 3.365 ± 0.04	2.501ArgGln: 2.501 ± 0.036	6.194ArgArg: 6.194 ± 0.071	3.623ArgSer: 3.623 ± 0.045	3.584ArgThr: 3.584 ± 0.049	5.714ArgVal: 5.714 ± 0.061	1.102ArgTrp: 1.102 ± 0.023	2.133ArgTyr: 2.133 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.847SerAla: 6.847 ± 0.065	0.435SerCys: 0.435 ± 0.015	2.796SerAsp: 2.796 ± 0.035	2.162SerGlu: 2.162 ± 0.034	2.082SerPhe: 2.082 ± 0.035	5.503SerGly: 5.503 ± 0.098	1.174SerHis: 1.174 ± 0.024	2.59SerIle: 2.59 ± 0.041	1.315SerLys: 1.315 ± 0.027	5.665SerLeu: 5.665 ± 0.064	1.247SerMet: 1.247 ± 0.026	1.54SerAsn: 1.54 ± 0.036	2.904SerPro: 2.904 ± 0.039	1.737SerGln: 1.737 ± 0.034	3.83SerArg: 3.83 ± 0.047	3.191SerSer: 3.191 ± 0.059	3.06SerThr: 3.06 ± 0.072	4.368SerVal: 4.368 ± 0.056	0.694SerTrp: 0.694 ± 0.02	1.346SerTyr: 1.346 ± 0.028	0.0SerXaa: 0.0 ± 0.001
Thr	6.095ThrAla: 6.095 ± 0.08	0.387ThrCys: 0.387 ± 0.015	2.815ThrAsp: 2.815 ± 0.042	2.094ThrGlu: 2.094 ± 0.035	1.966ThrPhe: 1.966 ± 0.037	4.974ThrGly: 4.974 ± 0.105	1.22ThrHis: 1.22 ± 0.024	2.563ThrIle: 2.563 ± 0.046	1.182ThrLys: 1.182 ± 0.026	6.758ThrLeu: 6.758 ± 0.075	1.165ThrMet: 1.165 ± 0.024	1.384ThrAsn: 1.384 ± 0.049	3.648ThrPro: 3.648 ± 0.054	1.835ThrGln: 1.835 ± 0.028	3.661ThrArg: 3.661 ± 0.044	2.86ThrSer: 2.86 ± 0.049	3.156ThrThr: 3.156 ± 0.075	4.455ThrVal: 4.455 ± 0.065	0.721ThrTrp: 0.721 ± 0.021	1.137ThrTyr: 1.137 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	10.451ValAla: 10.451 ± 0.094	0.827ValCys: 0.827 ± 0.022	4.387ValAsp: 4.387 ± 0.052	4.258ValGlu: 4.258 ± 0.058	2.844ValPhe: 2.844 ± 0.04	5.875ValGly: 5.875 ± 0.055	1.54ValHis: 1.54 ± 0.029	3.53ValIle: 3.53 ± 0.045	2.237ValLys: 2.237 ± 0.04	8.047ValLeu: 8.047 ± 0.084	1.698ValMet: 1.698 ± 0.032	2.261ValAsn: 2.261 ± 0.044	4.07ValPro: 4.07 ± 0.049	2.464ValGln: 2.464 ± 0.037	5.488ValArg: 5.488 ± 0.064	4.712ValSer: 4.712 ± 0.06	4.556ValThr: 4.556 ± 0.054	6.618ValVal: 6.618 ± 0.066	0.975ValTrp: 0.975 ± 0.023	1.751ValTyr: 1.751 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.16TrpAla: 1.16 ± 0.024	0.155TrpCys: 0.155 ± 0.01	0.638TrpAsp: 0.638 ± 0.021	0.473TrpGlu: 0.473 ± 0.016	0.573TrpPhe: 0.573 ± 0.019	0.844TrpGly: 0.844 ± 0.025	0.381TrpHis: 0.381 ± 0.014	0.692TrpIle: 0.692 ± 0.021	0.383TrpLys: 0.383 ± 0.014	1.97TrpLeu: 1.97 ± 0.042	0.328TrpMet: 0.328 ± 0.012	0.456TrpAsn: 0.456 ± 0.015	0.673TrpPro: 0.673 ± 0.019	0.68TrpGln: 0.68 ± 0.021	1.305TrpArg: 1.305 ± 0.03	0.827TrpSer: 0.827 ± 0.022	0.741TrpThr: 0.741 ± 0.024	0.892TrpVal: 0.892 ± 0.024	0.226TrpTrp: 0.226 ± 0.011	0.314TrpTyr: 0.314 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.895TyrAla: 2.895 ± 0.04	0.249TyrCys: 0.249 ± 0.012	1.461TyrAsp: 1.461 ± 0.029	1.198TyrGlu: 1.198 ± 0.023	0.964TyrPhe: 0.964 ± 0.024	2.222TyrGly: 2.222 ± 0.036	0.502TyrHis: 0.502 ± 0.014	0.736TyrIle: 0.736 ± 0.02	0.48TyrLys: 0.48 ± 0.019	2.521TyrLeu: 2.521 ± 0.041	0.412TyrMet: 0.412 ± 0.012	0.619TyrAsn: 0.619 ± 0.02	1.268TyrPro: 1.268 ± 0.023	0.824TyrGln: 0.824 ± 0.019	2.048TyrArg: 2.048 ± 0.035	1.206TyrSer: 1.206 ± 0.03	1.259TyrThr: 1.259 ± 0.031	1.961TyrVal: 1.961 ± 0.034	0.395TyrTrp: 0.395 ± 0.013	0.639TyrTyr: 0.639 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.001	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 6189 proteins (2028450 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---