Amino acid dipepetide frequency for Sinobaca qinghaiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.261AlaAla: 9.261 ± 0.131
0.663AlaCys: 0.663 ± 0.027
4.485AlaAsp: 4.485 ± 0.064
6.628AlaGlu: 6.628 ± 0.109
3.875AlaPhe: 3.875 ± 0.077
7.342AlaGly: 7.342 ± 0.1
1.488AlaHis: 1.488 ± 0.04
4.784AlaIle: 4.784 ± 0.075
3.787AlaLys: 3.787 ± 0.072
8.176AlaLeu: 8.176 ± 0.101
2.343AlaMet: 2.343 ± 0.053
2.188AlaAsn: 2.188 ± 0.044
2.609AlaPro: 2.609 ± 0.056
2.226AlaGln: 2.226 ± 0.052
3.069AlaArg: 3.069 ± 0.062
5.299AlaSer: 5.299 ± 0.082
2.833AlaThr: 2.833 ± 0.053
7.619AlaVal: 7.619 ± 0.097
0.754AlaTrp: 0.754 ± 0.025
2.583AlaTyr: 2.583 ± 0.048
0.0AlaXaa: 0.0 ± 0.0
Cys
0.43CysAla: 0.43 ± 0.021
0.079CysCys: 0.079 ± 0.009
0.363CysAsp: 0.363 ± 0.022
0.386CysGlu: 0.386 ± 0.022
0.304CysPhe: 0.304 ± 0.018
0.639CysGly: 0.639 ± 0.025
0.181CysHis: 0.181 ± 0.014
0.453CysIle: 0.453 ± 0.022
0.224CysLys: 0.224 ± 0.017
0.618CysLeu: 0.618 ± 0.026
0.162CysMet: 0.162 ± 0.014
0.198CysAsn: 0.198 ± 0.014
0.332CysPro: 0.332 ± 0.022
0.187CysGln: 0.187 ± 0.013
0.42CysArg: 0.42 ± 0.023
0.474CysSer: 0.474 ± 0.021
0.406CysThr: 0.406 ± 0.02
0.332CysVal: 0.332 ± 0.017
0.06CysTrp: 0.06 ± 0.008
0.221CysTyr: 0.221 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
3.608AspAla: 3.608 ± 0.06
0.301AspCys: 0.301 ± 0.018
2.402AspAsp: 2.402 ± 0.062
4.269AspGlu: 4.269 ± 0.077
2.121AspPhe: 2.121 ± 0.049
3.339AspGly: 3.339 ± 0.056
1.284AspHis: 1.284 ± 0.04
4.34AspIle: 4.34 ± 0.062
2.987AspLys: 2.987 ± 0.059
4.66AspLeu: 4.66 ± 0.07
1.633AspMet: 1.633 ± 0.038
1.845AspAsn: 1.845 ± 0.039
2.208AspPro: 2.208 ± 0.044
1.883AspGln: 1.883 ± 0.05
2.45AspArg: 2.45 ± 0.045
2.732AspSer: 2.732 ± 0.058
2.862AspThr: 2.862 ± 0.052
3.817AspVal: 3.817 ± 0.063
0.66AspTrp: 0.66 ± 0.027
2.106AspTyr: 2.106 ± 0.054
0.0AspXaa: 0.0 ± 0.0
Glu
7.443GluAla: 7.443 ± 0.105
0.367GluCys: 0.367 ± 0.021
4.6GluAsp: 4.6 ± 0.086
9.487GluGlu: 9.487 ± 0.171
2.267GluPhe: 2.267 ± 0.048
5.026GluGly: 5.026 ± 0.082
1.718GluHis: 1.718 ± 0.047
4.782GluIle: 4.782 ± 0.079
6.666GluLys: 6.666 ± 0.097
6.968GluLeu: 6.968 ± 0.092
2.515GluMet: 2.515 ± 0.053
3.705GluAsn: 3.705 ± 0.071
2.357GluPro: 2.357 ± 0.062
3.889GluGln: 3.889 ± 0.077
3.712GluArg: 3.712 ± 0.07
4.185GluSer: 4.185 ± 0.078
4.779GluThr: 4.779 ± 0.086
4.892GluVal: 4.892 ± 0.078
1.099GluTrp: 1.099 ± 0.034
2.272GluTyr: 2.272 ± 0.055
0.0GluXaa: 0.0 ± 0.0
Phe
3.237PheAla: 3.237 ± 0.065
0.304PheCys: 0.304 ± 0.017
2.22PheAsp: 2.22 ± 0.046
2.704PheGlu: 2.704 ± 0.051
2.321PhePhe: 2.321 ± 0.058
3.158PheGly: 3.158 ± 0.074
0.983PheHis: 0.983 ± 0.03
3.555PheIle: 3.555 ± 0.074
1.882PheLys: 1.882 ± 0.039
4.41PheLeu: 4.41 ± 0.081
1.193PheMet: 1.193 ± 0.037
1.5PheAsn: 1.5 ± 0.043
1.786PhePro: 1.786 ± 0.044
1.672PheGln: 1.672 ± 0.04
1.527PheArg: 1.527 ± 0.038
3.213PheSer: 3.213 ± 0.068
2.666PheThr: 2.666 ± 0.055
2.786PheVal: 2.786 ± 0.061
0.496PheTrp: 0.496 ± 0.024
1.549PheTyr: 1.549 ± 0.041
0.0PheXaa: 0.0 ± 0.0
Gly
5.816GlyAla: 5.816 ± 0.095
0.553GlyCys: 0.553 ± 0.027
3.202GlyAsp: 3.202 ± 0.055
5.037GlyGlu: 5.037 ± 0.081
3.402GlyPhe: 3.402 ± 0.064
5.464GlyGly: 5.464 ± 0.083
1.438GlyHis: 1.438 ± 0.039
5.813GlyIle: 5.813 ± 0.093
4.011GlyLys: 4.011 ± 0.074
6.739GlyLeu: 6.739 ± 0.102
2.422GlyMet: 2.422 ± 0.053
2.343GlyAsn: 2.343 ± 0.052
1.976GlyPro: 1.976 ± 0.048
1.997GlyGln: 1.997 ± 0.046
3.467GlyArg: 3.467 ± 0.07
4.86GlySer: 4.86 ± 0.066
4.421GlyThr: 4.421 ± 0.073
5.054GlyVal: 5.054 ± 0.068
0.897GlyTrp: 0.897 ± 0.034
2.59GlyTyr: 2.59 ± 0.054
0.0GlyXaa: 0.0 ± 0.0
His
1.604HisAla: 1.604 ± 0.043
0.176HisCys: 0.176 ± 0.013
0.96HisAsp: 0.96 ± 0.033
1.433HisGlu: 1.433 ± 0.045
1.067HisPhe: 1.067 ± 0.03
1.543HisGly: 1.543 ± 0.039
0.733HisHis: 0.733 ± 0.029
1.561HisIle: 1.561 ± 0.047
0.958HisLys: 0.958 ± 0.031
2.117HisLeu: 2.117 ± 0.047
0.606HisMet: 0.606 ± 0.025
0.75HisAsn: 0.75 ± 0.025
1.197HisPro: 1.197 ± 0.04
0.881HisGln: 0.881 ± 0.031
0.973HisArg: 0.973 ± 0.027
1.348HisSer: 1.348 ± 0.037
1.238HisThr: 1.238 ± 0.035
1.523HisVal: 1.523 ± 0.046
0.225HisTrp: 0.225 ± 0.015
0.864HisTyr: 0.864 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
5.888IleAla: 5.888 ± 0.096
0.538IleCys: 0.538 ± 0.025
3.947IleAsp: 3.947 ± 0.067
5.419IleGlu: 5.419 ± 0.073
2.852IlePhe: 2.852 ± 0.07
5.646IleGly: 5.646 ± 0.089
1.603IleHis: 1.603 ± 0.045
5.245IleIle: 5.245 ± 0.09
3.72IleLys: 3.72 ± 0.075
6.273IleLeu: 6.273 ± 0.102
1.746IleMet: 1.746 ± 0.039
2.802IleAsn: 2.802 ± 0.063
3.077IlePro: 3.077 ± 0.057
2.55IleGln: 2.55 ± 0.051
2.984IleArg: 2.984 ± 0.054
4.523IleSer: 4.523 ± 0.074
4.243IleThr: 4.243 ± 0.069
5.001IleVal: 5.001 ± 0.08
0.654IleTrp: 0.654 ± 0.027
2.163IleTyr: 2.163 ± 0.054
0.0IleXaa: 0.0 ± 0.0
Lys
4.776LysAla: 4.776 ± 0.065
0.232LysCys: 0.232 ± 0.014
3.353LysAsp: 3.353 ± 0.065
6.89LysGlu: 6.89 ± 0.114
1.19LysPhe: 1.19 ± 0.036
3.851LysGly: 3.851 ± 0.063
1.256LysHis: 1.256 ± 0.036
3.349LysIle: 3.349 ± 0.064
5.459LysLys: 5.459 ± 0.086
4.409LysLeu: 4.409 ± 0.076
1.966LysMet: 1.966 ± 0.053
2.719LysAsn: 2.719 ± 0.061
2.067LysPro: 2.067 ± 0.048
3.039LysGln: 3.039 ± 0.063
3.069LysArg: 3.069 ± 0.054
2.982LysSer: 2.982 ± 0.063
3.327LysThr: 3.327 ± 0.064
3.599LysVal: 3.599 ± 0.068
0.726LysTrp: 0.726 ± 0.029
1.649LysTyr: 1.649 ± 0.045
0.0LysXaa: 0.0 ± 0.0
Leu
7.746LeuAla: 7.746 ± 0.088
0.644LeuCys: 0.644 ± 0.025
4.698LeuAsp: 4.698 ± 0.07
7.103LeuGlu: 7.103 ± 0.088
4.794LeuPhe: 4.794 ± 0.103
6.244LeuGly: 6.244 ± 0.097
2.182LeuHis: 2.182 ± 0.051
6.4LeuIle: 6.4 ± 0.104
5.386LeuLys: 5.386 ± 0.087
9.917LeuLeu: 9.917 ± 0.146
2.503LeuMet: 2.503 ± 0.05
3.409LeuAsn: 3.409 ± 0.062
4.169LeuPro: 4.169 ± 0.07
3.937LeuGln: 3.937 ± 0.068
3.656LeuArg: 3.656 ± 0.069
6.414LeuSer: 6.414 ± 0.079
5.4LeuThr: 5.4 ± 0.077
5.682LeuVal: 5.682 ± 0.095
0.836LeuTrp: 0.836 ± 0.028
3.08LeuTyr: 3.08 ± 0.066
0.0LeuXaa: 0.0 ± 0.0
Met
2.531MetAla: 2.531 ± 0.049
0.124MetCys: 0.124 ± 0.01
1.708MetAsp: 1.708 ± 0.047
2.486MetGlu: 2.486 ± 0.054
1.057MetPhe: 1.057 ± 0.039
1.9MetGly: 1.9 ± 0.05
0.565MetHis: 0.565 ± 0.023
2.146MetIle: 2.146 ± 0.05
2.39MetLys: 2.39 ± 0.049
2.724MetLeu: 2.724 ± 0.058
0.936MetMet: 0.936 ± 0.036
1.672MetAsn: 1.672 ± 0.037
1.154MetPro: 1.154 ± 0.039
1.126MetGln: 1.126 ± 0.036
1.081MetArg: 1.081 ± 0.033
1.636MetSer: 1.636 ± 0.039
1.802MetThr: 1.802 ± 0.041
1.682MetVal: 1.682 ± 0.037
0.21MetTrp: 0.21 ± 0.016
0.806MetTyr: 0.806 ± 0.026
0.0MetXaa: 0.0 ± 0.0
Asn
2.689AsnAla: 2.689 ± 0.047
0.224AsnCys: 0.224 ± 0.016
1.967AsnAsp: 1.967 ± 0.05
3.204AsnGlu: 3.204 ± 0.066
1.24AsnPhe: 1.24 ± 0.04
2.811AsnGly: 2.811 ± 0.057
0.825AsnHis: 0.825 ± 0.032
2.971AsnIle: 2.971 ± 0.058
2.462AsnLys: 2.462 ± 0.061
2.943AsnLeu: 2.943 ± 0.066
1.167AsnMet: 1.167 ± 0.038
1.705AsnAsn: 1.705 ± 0.048
1.798AsnPro: 1.798 ± 0.047
1.553AsnGln: 1.553 ± 0.037
1.842AsnArg: 1.842 ± 0.043
1.898AsnSer: 1.898 ± 0.048
2.16AsnThr: 2.16 ± 0.05
2.714AsnVal: 2.714 ± 0.058
0.447AsnTrp: 0.447 ± 0.021
1.155AsnTyr: 1.155 ± 0.035
0.0AsnXaa: 0.0 ± 0.0
Pro
3.401ProAla: 3.401 ± 0.061
0.222ProCys: 0.222 ± 0.014
2.393ProAsp: 2.393 ± 0.049
3.817ProGlu: 3.817 ± 0.067
1.937ProPhe: 1.937 ± 0.045
2.904ProGly: 2.904 ± 0.062
0.835ProHis: 0.835 ± 0.029
2.422ProIle: 2.422 ± 0.052
1.789ProLys: 1.789 ± 0.043
3.694ProLeu: 3.694 ± 0.065
0.94ProMet: 0.94 ± 0.031
1.247ProAsn: 1.247 ± 0.039
1.201ProPro: 1.201 ± 0.038
1.057ProGln: 1.057 ± 0.03
1.151ProArg: 1.151 ± 0.03
2.464ProSer: 2.464 ± 0.048
1.538ProThr: 1.538 ± 0.036
3.292ProVal: 3.292 ± 0.058
0.378ProTrp: 0.378 ± 0.02
1.341ProTyr: 1.341 ± 0.037
0.0ProXaa: 0.0 ± 0.0
Gln
3.449GlnAla: 3.449 ± 0.067
0.171GlnCys: 0.171 ± 0.014
1.598GlnAsp: 1.598 ± 0.036
3.513GlnGlu: 3.513 ± 0.072
1.323GlnPhe: 1.323 ± 0.035
2.285GlnGly: 2.285 ± 0.049
0.82GlnHis: 0.82 ± 0.026
2.272GlnIle: 2.272 ± 0.051
2.585GlnLys: 2.585 ± 0.054
3.557GlnLeu: 3.557 ± 0.066
1.251GlnMet: 1.251 ± 0.037
1.361GlnAsn: 1.361 ± 0.038
1.299GlnPro: 1.299 ± 0.041
1.886GlnGln: 1.886 ± 0.052
1.622GlnArg: 1.622 ± 0.043
2.197GlnSer: 2.197 ± 0.043
2.147GlnThr: 2.147 ± 0.047
2.268GlnVal: 2.268 ± 0.054
0.463GlnTrp: 0.463 ± 0.022
1.112GlnTyr: 1.112 ± 0.037
0.0GlnXaa: 0.0 ± 0.0
Arg
2.849ArgAla: 2.849 ± 0.056
0.247ArgCys: 0.247 ± 0.017
2.135ArgAsp: 2.135 ± 0.055
3.59ArgGlu: 3.59 ± 0.066
1.927ArgPhe: 1.927 ± 0.046
2.549ArgGly: 2.549 ± 0.052
0.932ArgHis: 0.932 ± 0.03
3.018ArgIle: 3.018 ± 0.052
2.988ArgLys: 2.988 ± 0.057
4.276ArgLeu: 4.276 ± 0.064
1.466ArgMet: 1.466 ± 0.04
1.57ArgAsn: 1.57 ± 0.041
1.533ArgPro: 1.533 ± 0.04
1.697ArgGln: 1.697 ± 0.043
2.412ArgArg: 2.412 ± 0.046
2.69ArgSer: 2.69 ± 0.05
2.396ArgThr: 2.396 ± 0.05
2.634ArgVal: 2.634 ± 0.058
0.441ArgTrp: 0.441 ± 0.021
1.581ArgTyr: 1.581 ± 0.04
0.0ArgXaa: 0.0 ± 0.0
Ser
4.702SerAla: 4.702 ± 0.067
0.384SerCys: 0.384 ± 0.017
2.812SerAsp: 2.812 ± 0.053
4.164SerGlu: 4.164 ± 0.072
3.398SerPhe: 3.398 ± 0.061
5.014SerGly: 5.014 ± 0.074
1.291SerHis: 1.291 ± 0.034
4.939SerIle: 4.939 ± 0.076
3.05SerLys: 3.05 ± 0.061
6.23SerLeu: 6.23 ± 0.091
2.029SerMet: 2.029 ± 0.041
2.069SerAsn: 2.069 ± 0.052
2.361SerPro: 2.361 ± 0.052
1.882SerGln: 1.882 ± 0.043
2.953SerArg: 2.953 ± 0.048
4.694SerSer: 4.694 ± 0.095
3.18SerThr: 3.18 ± 0.064
4.235SerVal: 4.235 ± 0.07
0.692SerTrp: 0.692 ± 0.028
2.353SerTyr: 2.353 ± 0.056
0.0SerXaa: 0.0 ± 0.0
Thr
5.172ThrAla: 5.172 ± 0.077
0.355ThrCys: 0.355 ± 0.021
2.789ThrAsp: 2.789 ± 0.052
4.104ThrGlu: 4.104 ± 0.079
2.63ThrPhe: 2.63 ± 0.056
4.667ThrGly: 4.667 ± 0.067
1.05ThrHis: 1.05 ± 0.029
4.236ThrIle: 4.236 ± 0.071
2.925ThrLys: 2.925 ± 0.052
5.025ThrLeu: 5.025 ± 0.067
1.554ThrMet: 1.554 ± 0.042
2.124ThrAsn: 2.124 ± 0.046
2.277ThrPro: 2.277 ± 0.045
1.348ThrGln: 1.348 ± 0.036
1.918ThrArg: 1.918 ± 0.045
3.413ThrSer: 3.413 ± 0.053
2.881ThrThr: 2.881 ± 0.058
4.082ThrVal: 4.082 ± 0.061
0.558ThrTrp: 0.558 ± 0.023
1.91ThrTyr: 1.91 ± 0.045
0.0ThrXaa: 0.0 ± 0.0
Val
4.438ValAla: 4.438 ± 0.078
0.55ValCys: 0.55 ± 0.024
3.542ValAsp: 3.542 ± 0.061
5.134ValGlu: 5.134 ± 0.076
3.29ValPhe: 3.29 ± 0.062
4.097ValGly: 4.097 ± 0.077
1.544ValHis: 1.544 ± 0.036
5.392ValIle: 5.392 ± 0.089
3.936ValLys: 3.936 ± 0.063
7.124ValLeu: 7.124 ± 0.087
2.01ValMet: 2.01 ± 0.044
2.728ValAsn: 2.728 ± 0.056
2.919ValPro: 2.919 ± 0.064
2.542ValGln: 2.542 ± 0.048
2.683ValArg: 2.683 ± 0.056
4.671ValSer: 4.671 ± 0.072
4.232ValThr: 4.232 ± 0.062
4.761ValVal: 4.761 ± 0.083
0.694ValTrp: 0.694 ± 0.027
2.356ValTyr: 2.356 ± 0.047
0.0ValXaa: 0.0 ± 0.0
Trp
0.638TrpAla: 0.638 ± 0.026
0.07TrpCys: 0.07 ± 0.008
0.498TrpAsp: 0.498 ± 0.024
0.852TrpGlu: 0.852 ± 0.03
0.478TrpPhe: 0.478 ± 0.026
0.68TrpGly: 0.68 ± 0.028
0.233TrpHis: 0.233 ± 0.015
0.857TrpIle: 0.857 ± 0.029
0.9TrpLys: 0.9 ± 0.032
1.143TrpLeu: 1.143 ± 0.034
0.404TrpMet: 0.404 ± 0.021
0.565TrpAsn: 0.565 ± 0.028
0.333TrpPro: 0.333 ± 0.019
0.409TrpGln: 0.409 ± 0.02
0.399TrpArg: 0.399 ± 0.022
0.655TrpSer: 0.655 ± 0.025
0.573TrpThr: 0.573 ± 0.026
0.603TrpVal: 0.603 ± 0.026
0.137TrpTrp: 0.137 ± 0.014
0.347TrpTyr: 0.347 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.333TyrAla: 2.333 ± 0.048
0.268TyrCys: 0.268 ± 0.015
1.836TyrAsp: 1.836 ± 0.042
2.511TyrGlu: 2.511 ± 0.053
1.687TyrPhe: 1.687 ± 0.042
2.344TyrGly: 2.344 ± 0.045
0.796TyrHis: 0.796 ± 0.03
2.339TyrIle: 2.339 ± 0.047
1.802TyrLys: 1.802 ± 0.048
3.195TyrLeu: 3.195 ± 0.054
0.89TyrMet: 0.89 ± 0.031
1.273TyrAsn: 1.273 ± 0.037
1.371TyrPro: 1.371 ± 0.031
1.418TyrGln: 1.418 ± 0.04
1.542TyrArg: 1.542 ± 0.041
2.083TyrSer: 2.083 ± 0.046
1.937TyrThr: 1.937 ± 0.042
2.066TyrVal: 2.066 ± 0.051
0.346TyrTrp: 0.346 ± 0.02
1.338TyrTyr: 1.338 ± 0.039
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3379 proteins (996966 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski