Amino acid dipepetide frequency for Hubei tombus-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.172AlaAla: 4.172 ± 1.935
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
2.782AlaGlu: 2.782 ± 2.665
5.563AlaPhe: 5.563 ± 3.267
2.782AlaGly: 2.782 ± 2.665
4.172AlaHis: 4.172 ± 1.935
4.172AlaIle: 4.172 ± 0.128
2.782AlaLys: 2.782 ± 1.46
4.172AlaLeu: 4.172 ± 0.128
0.0AlaMet: 0.0 ± 0.0
1.391AlaAsn: 1.391 ± 1.332
1.391AlaPro: 1.391 ± 0.73
1.391AlaGln: 1.391 ± 0.73
2.782AlaArg: 2.782 ± 0.602
6.954AlaSer: 6.954 ± 1.588
6.954AlaThr: 6.954 ± 0.475
1.391AlaVal: 1.391 ± 1.332
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
4.172CysAsp: 4.172 ± 2.19
2.782CysGlu: 2.782 ± 1.46
2.782CysPhe: 2.782 ± 1.46
1.391CysGly: 1.391 ± 0.73
0.0CysHis: 0.0 ± 0.0
1.391CysIle: 1.391 ± 0.73
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
2.782CysMet: 2.782 ± 1.46
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.391CysGln: 1.391 ± 0.73
2.782CysArg: 2.782 ± 0.602
4.172CysSer: 4.172 ± 0.128
1.391CysThr: 1.391 ± 1.332
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.172AspAla: 4.172 ± 0.128
5.563AspCys: 5.563 ± 0.858
2.782AspAsp: 2.782 ± 0.602
6.954AspGlu: 6.954 ± 0.475
1.391AspPhe: 1.391 ± 0.73
2.782AspGly: 2.782 ± 0.602
0.0AspHis: 0.0 ± 0.0
4.172AspIle: 4.172 ± 0.128
2.782AspLys: 2.782 ± 1.46
1.391AspLeu: 1.391 ± 1.332
0.0AspMet: 0.0 ± 0.0
5.563AspAsn: 5.563 ± 0.858
0.0AspPro: 0.0 ± 0.0
0.0AspGln: 0.0 ± 0.0
1.391AspArg: 1.391 ± 1.332
4.172AspSer: 4.172 ± 2.19
2.782AspThr: 2.782 ± 1.46
1.391AspVal: 1.391 ± 1.332
1.391AspTrp: 1.391 ± 0.73
1.391AspTyr: 1.391 ± 0.73
0.0AspXaa: 0.0 ± 0.0
Glu
4.172GluAla: 4.172 ± 0.128
1.391GluCys: 1.391 ± 0.73
0.0GluAsp: 0.0 ± 0.0
5.563GluGlu: 5.563 ± 0.858
1.391GluPhe: 1.391 ± 0.73
0.0GluGly: 0.0 ± 0.0
2.782GluHis: 2.782 ± 1.46
4.172GluIle: 4.172 ± 0.128
4.172GluLys: 4.172 ± 0.128
6.954GluLeu: 6.954 ± 0.475
2.782GluMet: 2.782 ± 0.602
2.782GluAsn: 2.782 ± 0.602
4.172GluPro: 4.172 ± 3.997
4.172GluGln: 4.172 ± 0.128
2.782GluArg: 2.782 ± 0.602
1.391GluSer: 1.391 ± 1.332
4.172GluThr: 4.172 ± 0.128
2.782GluVal: 2.782 ± 1.46
1.391GluTrp: 1.391 ± 1.332
1.391GluTyr: 1.391 ± 1.332
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
5.563PheAsp: 5.563 ± 1.205
2.782PheGlu: 2.782 ± 0.602
1.391PhePhe: 1.391 ± 0.73
0.0PheGly: 0.0 ± 0.0
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
5.563PheLys: 5.563 ± 1.205
4.172PheLeu: 4.172 ± 0.128
0.0PheMet: 0.0 ± 0.0
1.391PheAsn: 1.391 ± 0.73
1.391PhePro: 1.391 ± 0.73
2.782PheGln: 2.782 ± 0.602
1.391PheArg: 1.391 ± 0.73
0.0PheSer: 0.0 ± 0.0
2.782PheThr: 2.782 ± 1.46
4.172PheVal: 4.172 ± 0.128
0.0PheTrp: 0.0 ± 0.0
1.391PheTyr: 1.391 ± 0.73
0.0PheXaa: 0.0 ± 0.0
Gly
1.391GlyAla: 1.391 ± 0.73
1.391GlyCys: 1.391 ± 0.73
2.782GlyAsp: 2.782 ± 1.46
1.391GlyGlu: 1.391 ± 1.332
1.391GlyPhe: 1.391 ± 0.73
2.782GlyGly: 2.782 ± 2.665
1.391GlyHis: 1.391 ± 1.332
0.0GlyIle: 0.0 ± 0.0
1.391GlyLys: 1.391 ± 0.73
1.391GlyLeu: 1.391 ± 0.73
0.0GlyMet: 0.0 ± 0.0
1.391GlyAsn: 1.391 ± 1.332
1.391GlyPro: 1.391 ± 1.332
1.391GlyGln: 1.391 ± 1.332
2.782GlyArg: 2.782 ± 1.46
2.782GlySer: 2.782 ± 2.665
1.391GlyThr: 1.391 ± 0.73
1.391GlyVal: 1.391 ± 0.73
2.782GlyTrp: 2.782 ± 1.46
5.563GlyTyr: 5.563 ± 3.267
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.391HisCys: 1.391 ± 0.73
2.782HisAsp: 2.782 ± 0.602
1.391HisGlu: 1.391 ± 0.73
1.391HisPhe: 1.391 ± 1.332
0.0HisGly: 0.0 ± 0.0
2.782HisHis: 2.782 ± 0.602
2.782HisIle: 2.782 ± 2.665
0.0HisLys: 0.0 ± 0.0
2.782HisLeu: 2.782 ± 0.602
2.782HisMet: 2.782 ± 1.099
1.391HisAsn: 1.391 ± 0.73
0.0HisPro: 0.0 ± 0.0
4.172HisGln: 4.172 ± 0.128
4.172HisArg: 4.172 ± 2.19
0.0HisSer: 0.0 ± 0.0
1.391HisThr: 1.391 ± 0.73
1.391HisVal: 1.391 ± 0.73
1.391HisTrp: 1.391 ± 0.73
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.172IleAla: 4.172 ± 1.935
1.391IleCys: 1.391 ± 0.73
5.563IleAsp: 5.563 ± 0.858
2.782IleGlu: 2.782 ± 1.46
1.391IlePhe: 1.391 ± 0.73
1.391IleGly: 1.391 ± 1.332
2.782IleHis: 2.782 ± 1.46
2.782IleIle: 2.782 ± 0.602
4.172IleLys: 4.172 ± 2.19
5.563IleLeu: 5.563 ± 2.92
2.782IleMet: 2.782 ± 1.46
0.0IleAsn: 0.0 ± 0.0
4.172IlePro: 4.172 ± 3.997
2.782IleGln: 2.782 ± 1.46
0.0IleArg: 0.0 ± 0.0
5.563IleSer: 5.563 ± 0.858
5.563IleThr: 5.563 ± 0.858
1.391IleVal: 1.391 ± 0.73
0.0IleTrp: 0.0 ± 0.0
2.782IleTyr: 2.782 ± 0.602
0.0IleXaa: 0.0 ± 0.0
Lys
5.563LysAla: 5.563 ± 0.858
4.172LysCys: 4.172 ± 2.19
1.391LysAsp: 1.391 ± 1.332
0.0LysGlu: 0.0 ± 0.0
1.391LysPhe: 1.391 ± 1.332
2.782LysGly: 2.782 ± 0.602
4.172LysHis: 4.172 ± 0.128
2.782LysIle: 2.782 ± 1.46
1.391LysLys: 1.391 ± 0.73
4.172LysLeu: 4.172 ± 0.128
1.391LysMet: 1.391 ± 0.73
1.391LysAsn: 1.391 ± 1.332
9.736LysPro: 9.736 ± 1.077
4.172LysGln: 4.172 ± 0.128
2.782LysArg: 2.782 ± 1.46
1.391LysSer: 1.391 ± 0.73
6.954LysThr: 6.954 ± 3.65
4.172LysVal: 4.172 ± 2.19
1.391LysTrp: 1.391 ± 1.332
4.172LysTyr: 4.172 ± 2.19
0.0LysXaa: 0.0 ± 0.0
Leu
5.563LeuAla: 5.563 ± 5.33
1.391LeuCys: 1.391 ± 0.73
6.954LeuAsp: 6.954 ± 1.588
5.563LeuGlu: 5.563 ± 0.858
0.0LeuPhe: 0.0 ± 0.0
2.782LeuGly: 2.782 ± 0.602
1.391LeuHis: 1.391 ± 0.73
4.172LeuIle: 4.172 ± 0.128
12.517LeuLys: 12.517 ± 2.446
11.127LeuLeu: 11.127 ± 2.41
4.172LeuMet: 4.172 ± 0.128
6.954LeuAsn: 6.954 ± 0.475
2.782LeuPro: 2.782 ± 0.602
4.172LeuGln: 4.172 ± 1.935
9.736LeuArg: 9.736 ± 0.985
6.954LeuSer: 6.954 ± 0.475
2.782LeuThr: 2.782 ± 1.46
2.782LeuVal: 2.782 ± 1.46
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.391MetAla: 1.391 ± 0.73
1.391MetCys: 1.391 ± 1.332
1.391MetAsp: 1.391 ± 1.332
2.782MetGlu: 2.782 ± 2.665
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.782MetIle: 2.782 ± 0.602
0.0MetLys: 0.0 ± 0.0
4.172MetLeu: 4.172 ± 0.128
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.782MetPro: 2.782 ± 1.46
1.391MetGln: 1.391 ± 0.73
2.782MetArg: 2.782 ± 1.46
1.391MetSer: 1.391 ± 0.73
1.391MetThr: 1.391 ± 0.73
4.172MetVal: 4.172 ± 0.128
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
2.782AsnAsp: 2.782 ± 0.602
1.391AsnGlu: 1.391 ± 1.332
0.0AsnPhe: 0.0 ± 0.0
2.782AsnGly: 2.782 ± 0.602
0.0AsnHis: 0.0 ± 0.0
2.782AsnIle: 2.782 ± 0.602
4.172AsnLys: 4.172 ± 1.935
1.391AsnLeu: 1.391 ± 0.73
1.391AsnMet: 1.391 ± 2.068
1.391AsnAsn: 1.391 ± 0.73
1.391AsnPro: 1.391 ± 0.73
1.391AsnGln: 1.391 ± 1.332
4.172AsnArg: 4.172 ± 2.19
4.172AsnSer: 4.172 ± 1.935
2.782AsnThr: 2.782 ± 1.46
2.782AsnVal: 2.782 ± 0.602
1.391AsnTrp: 1.391 ± 0.73
2.782AsnTyr: 2.782 ± 1.46
0.0AsnXaa: 0.0 ± 0.0
Pro
1.391ProAla: 1.391 ± 1.332
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
2.782ProGlu: 2.782 ± 0.602
0.0ProPhe: 0.0 ± 0.0
2.782ProGly: 2.782 ± 0.602
1.391ProHis: 1.391 ± 0.73
6.954ProIle: 6.954 ± 1.588
1.391ProLys: 1.391 ± 1.332
4.172ProLeu: 4.172 ± 1.935
1.391ProMet: 1.391 ± 0.73
2.782ProAsn: 2.782 ± 1.46
0.0ProPro: 0.0 ± 0.0
4.172ProGln: 4.172 ± 2.19
4.172ProArg: 4.172 ± 0.128
5.563ProSer: 5.563 ± 3.267
6.954ProThr: 6.954 ± 2.537
4.172ProVal: 4.172 ± 3.997
2.782ProTrp: 2.782 ± 1.46
1.391ProTyr: 1.391 ± 1.332
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.391GlnCys: 1.391 ± 0.73
1.391GlnAsp: 1.391 ± 0.73
1.391GlnGlu: 1.391 ± 1.332
0.0GlnPhe: 0.0 ± 0.0
1.391GlnGly: 1.391 ± 0.73
5.563GlnHis: 5.563 ± 1.205
2.782GlnIle: 2.782 ± 1.46
2.782GlnLys: 2.782 ± 1.46
8.345GlnLeu: 8.345 ± 0.255
2.782GlnMet: 2.782 ± 1.46
2.782GlnAsn: 2.782 ± 2.665
2.782GlnPro: 2.782 ± 0.602
5.563GlnGln: 5.563 ± 1.205
1.391GlnArg: 1.391 ± 0.73
1.391GlnSer: 1.391 ± 0.73
4.172GlnThr: 4.172 ± 1.935
8.345GlnVal: 8.345 ± 1.807
1.391GlnTrp: 1.391 ± 0.73
4.172GlnTyr: 4.172 ± 0.128
0.0GlnXaa: 0.0 ± 0.0
Arg
6.954ArgAla: 6.954 ± 3.65
0.0ArgCys: 0.0 ± 0.0
4.172ArgAsp: 4.172 ± 0.128
1.391ArgGlu: 1.391 ± 0.73
1.391ArgPhe: 1.391 ± 1.332
2.782ArgGly: 2.782 ± 0.602
2.782ArgHis: 2.782 ± 0.602
2.782ArgIle: 2.782 ± 1.46
2.782ArgLys: 2.782 ± 0.602
6.954ArgLeu: 6.954 ± 0.475
1.391ArgMet: 1.391 ± 0.73
4.172ArgAsn: 4.172 ± 2.19
2.782ArgPro: 2.782 ± 0.602
5.563ArgGln: 5.563 ± 1.205
2.782ArgArg: 2.782 ± 0.602
5.563ArgSer: 5.563 ± 0.858
2.782ArgThr: 2.782 ± 0.602
2.782ArgVal: 2.782 ± 0.602
0.0ArgTrp: 0.0 ± 0.0
5.563ArgTyr: 5.563 ± 2.92
0.0ArgXaa: 0.0 ± 0.0
Ser
5.563SerAla: 5.563 ± 3.267
0.0SerCys: 0.0 ± 0.0
1.391SerAsp: 1.391 ± 0.73
2.782SerGlu: 2.782 ± 0.602
8.345SerPhe: 8.345 ± 4.38
2.782SerGly: 2.782 ± 1.46
0.0SerHis: 0.0 ± 0.0
4.172SerIle: 4.172 ± 2.19
4.172SerLys: 4.172 ± 2.19
6.954SerLeu: 6.954 ± 1.588
1.391SerMet: 1.391 ± 1.332
0.0SerAsn: 0.0 ± 0.0
1.391SerPro: 1.391 ± 0.73
6.954SerGln: 6.954 ± 0.475
5.563SerArg: 5.563 ± 3.267
6.954SerSer: 6.954 ± 4.6
4.172SerThr: 4.172 ± 0.128
2.782SerVal: 2.782 ± 2.665
1.391SerTrp: 1.391 ± 1.332
2.782SerTyr: 2.782 ± 0.602
0.0SerXaa: 0.0 ± 0.0
Thr
4.172ThrAla: 4.172 ± 0.128
1.391ThrCys: 1.391 ± 0.73
1.391ThrAsp: 1.391 ± 0.73
4.172ThrGlu: 4.172 ± 1.935
2.782ThrPhe: 2.782 ± 2.665
4.172ThrGly: 4.172 ± 2.19
1.391ThrHis: 1.391 ± 0.73
1.391ThrIle: 1.391 ± 0.73
5.563ThrLys: 5.563 ± 1.205
6.954ThrLeu: 6.954 ± 0.475
0.0ThrMet: 0.0 ± 0.0
1.391ThrAsn: 1.391 ± 0.73
9.736ThrPro: 9.736 ± 0.985
2.782ThrGln: 2.782 ± 0.602
8.345ThrArg: 8.345 ± 0.255
5.563ThrSer: 5.563 ± 0.858
4.172ThrThr: 4.172 ± 2.19
1.391ThrVal: 1.391 ± 0.73
0.0ThrTrp: 0.0 ± 0.0
4.172ThrTyr: 4.172 ± 0.128
0.0ThrXaa: 0.0 ± 0.0
Val
1.391ValAla: 1.391 ± 1.332
2.782ValCys: 2.782 ± 0.602
2.782ValAsp: 2.782 ± 1.46
4.172ValGlu: 4.172 ± 0.128
1.391ValPhe: 1.391 ± 0.73
1.391ValGly: 1.391 ± 0.73
0.0ValHis: 0.0 ± 0.0
2.782ValIle: 2.782 ± 1.46
1.391ValLys: 1.391 ± 0.73
5.563ValLeu: 5.563 ± 1.205
1.391ValMet: 1.391 ± 1.332
4.172ValAsn: 4.172 ± 3.997
5.563ValPro: 5.563 ± 1.205
1.391ValGln: 1.391 ± 1.332
4.172ValArg: 4.172 ± 2.19
2.782ValSer: 2.782 ± 1.46
2.782ValThr: 2.782 ± 2.665
0.0ValVal: 0.0 ± 0.0
0.0ValTrp: 0.0 ± 0.0
1.391ValTyr: 1.391 ± 0.73
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.391TrpAsp: 1.391 ± 0.73
1.391TrpGlu: 1.391 ± 0.73
1.391TrpPhe: 1.391 ± 0.73
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.391TrpIle: 1.391 ± 1.332
4.172TrpLys: 4.172 ± 0.128
1.391TrpLeu: 1.391 ± 0.73
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.391TrpGln: 1.391 ± 0.73
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
2.782TrpThr: 2.782 ± 0.602
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.391TrpTyr: 1.391 ± 0.73
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.782TyrAla: 2.782 ± 2.665
1.391TyrCys: 1.391 ± 0.73
1.391TyrAsp: 1.391 ± 1.332
4.172TyrGlu: 4.172 ± 2.19
1.391TyrPhe: 1.391 ± 0.73
1.391TyrGly: 1.391 ± 1.332
1.391TyrHis: 1.391 ± 0.73
2.782TyrIle: 2.782 ± 1.46
4.172TyrLys: 4.172 ± 2.19
4.172TyrLeu: 4.172 ± 0.128
0.0TyrMet: 0.0 ± 0.0
1.391TyrAsn: 1.391 ± 0.73
2.782TyrPro: 2.782 ± 0.602
2.782TyrGln: 2.782 ± 1.46
1.391TyrArg: 1.391 ± 1.332
2.782TyrSer: 2.782 ± 0.602
2.782TyrThr: 2.782 ± 0.602
0.0TyrVal: 0.0 ± 0.0
1.391TyrTrp: 1.391 ± 0.73
5.563TyrTyr: 5.563 ± 0.858
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (720 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski