Amino acid dipepetide frequency for Tortoise microvirus 38

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.333AlaAla: 13.333 ± 1.977
0.0AlaCys: 0.0 ± 0.0
6.377AlaAsp: 6.377 ± 1.265
10.435AlaGlu: 10.435 ± 2.347
5.217AlaPhe: 5.217 ± 1.896
7.536AlaGly: 7.536 ± 1.489
2.319AlaHis: 2.319 ± 0.985
2.319AlaIle: 2.319 ± 1.251
7.536AlaLys: 7.536 ± 2.179
9.275AlaLeu: 9.275 ± 3.013
2.319AlaMet: 2.319 ± 1.259
4.058AlaAsn: 4.058 ± 2.518
5.797AlaPro: 5.797 ± 1.409
3.478AlaGln: 3.478 ± 1.782
4.638AlaArg: 4.638 ± 0.775
4.058AlaSer: 4.058 ± 2.009
6.957AlaThr: 6.957 ± 2.297
5.797AlaVal: 5.797 ± 1.956
1.739AlaTrp: 1.739 ± 1.009
1.159AlaTyr: 1.159 ± 0.91
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.159CysAsp: 1.159 ± 1.023
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.58CysGly: 0.58 ± 0.907
0.0CysHis: 0.0 ± 0.0
0.58CysIle: 0.58 ± 0.535
1.159CysLys: 1.159 ± 1.069
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.58CysPro: 0.58 ± 0.67
0.0CysGln: 0.0 ± 0.0
1.739CysArg: 1.739 ± 1.009
0.0CysSer: 0.0 ± 0.0
0.58CysThr: 0.58 ± 0.535
0.58CysVal: 0.58 ± 0.455
0.58CysTrp: 0.58 ± 0.535
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.797AspAla: 5.797 ± 3.026
0.0AspCys: 0.0 ± 0.0
3.478AspAsp: 3.478 ± 0.906
5.217AspGlu: 5.217 ± 1.131
1.739AspPhe: 1.739 ± 0.882
2.899AspGly: 2.899 ± 1.936
0.58AspHis: 0.58 ± 0.555
2.899AspIle: 2.899 ± 1.65
3.478AspLys: 3.478 ± 0.768
9.275AspLeu: 9.275 ± 1.47
1.159AspMet: 1.159 ± 1.023
1.739AspAsn: 1.739 ± 0.884
3.478AspPro: 3.478 ± 0.446
1.159AspGln: 1.159 ± 0.827
3.478AspArg: 3.478 ± 1.972
1.739AspSer: 1.739 ± 0.813
1.159AspThr: 1.159 ± 0.91
4.638AspVal: 4.638 ± 2.421
1.159AspTrp: 1.159 ± 0.692
3.478AspTyr: 3.478 ± 1.714
0.0AspXaa: 0.0 ± 0.0
Glu
7.536GluAla: 7.536 ± 5.044
0.58GluCys: 0.58 ± 0.455
1.739GluAsp: 1.739 ± 1.292
3.478GluGlu: 3.478 ± 2.351
0.0GluPhe: 0.0 ± 0.0
3.478GluGly: 3.478 ± 2.426
0.0GluHis: 0.0 ± 0.0
2.899GluIle: 2.899 ± 0.647
4.638GluLys: 4.638 ± 1.849
5.217GluLeu: 5.217 ± 1.144
2.319GluMet: 2.319 ± 1.208
3.478GluAsn: 3.478 ± 1.627
4.638GluPro: 4.638 ± 1.106
4.058GluGln: 4.058 ± 1.879
6.957GluArg: 6.957 ± 1.175
2.319GluSer: 2.319 ± 0.61
2.319GluThr: 2.319 ± 1.238
4.638GluVal: 4.638 ± 2.786
2.319GluTrp: 2.319 ± 1.32
1.159GluTyr: 1.159 ± 0.571
0.0GluXaa: 0.0 ± 0.0
Phe
4.058PheAla: 4.058 ± 2.597
1.739PheCys: 1.739 ± 1.095
4.058PheAsp: 4.058 ± 1.285
3.478PheGlu: 3.478 ± 1.523
1.159PhePhe: 1.159 ± 0.692
2.319PheGly: 2.319 ± 1.448
0.58PheHis: 0.58 ± 0.535
2.319PheIle: 2.319 ± 1.592
1.159PheLys: 1.159 ± 0.58
0.58PheLeu: 0.58 ± 0.67
0.0PheMet: 0.0 ± 0.0
2.319PheAsn: 2.319 ± 1.054
1.159PhePro: 1.159 ± 0.91
2.899PheGln: 2.899 ± 1.764
1.739PheArg: 1.739 ± 0.66
2.319PheSer: 2.319 ± 1.276
2.319PheThr: 2.319 ± 1.077
1.159PheVal: 1.159 ± 0.58
1.159PheTrp: 1.159 ± 0.854
0.58PheTyr: 0.58 ± 0.455
0.0PheXaa: 0.0 ± 0.0
Gly
5.797GlyAla: 5.797 ± 1.666
0.0GlyCys: 0.0 ± 0.0
5.797GlyAsp: 5.797 ± 1.181
6.957GlyGlu: 6.957 ± 1.447
2.319GlyPhe: 2.319 ± 1.054
8.696GlyGly: 8.696 ± 3.651
1.739GlyHis: 1.739 ± 1.105
4.058GlyIle: 4.058 ± 1.7
4.058GlyLys: 4.058 ± 1.992
4.638GlyLeu: 4.638 ± 2.095
1.739GlyMet: 1.739 ± 0.792
2.899GlyAsn: 2.899 ± 0.853
5.217GlyPro: 5.217 ± 2.529
1.159GlyGln: 1.159 ± 0.527
8.116GlyArg: 8.116 ± 1.099
2.319GlySer: 2.319 ± 0.837
3.478GlyThr: 3.478 ± 1.991
5.797GlyVal: 5.797 ± 2.951
1.159GlyTrp: 1.159 ± 0.854
0.58GlyTyr: 0.58 ± 0.455
0.0GlyXaa: 0.0 ± 0.0
His
2.899HisAla: 2.899 ± 1.142
0.0HisCys: 0.0 ± 0.0
0.58HisAsp: 0.58 ± 0.555
2.319HisGlu: 2.319 ± 1.68
2.899HisPhe: 2.899 ± 1.196
1.159HisGly: 1.159 ± 0.692
0.0HisHis: 0.0 ± 0.0
1.159HisIle: 1.159 ± 1.069
1.739HisLys: 1.739 ± 1.604
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.159HisAsn: 1.159 ± 1.091
0.0HisPro: 0.0 ± 0.0
0.58HisGln: 0.58 ± 0.67
1.159HisArg: 1.159 ± 1.111
1.739HisSer: 1.739 ± 0.926
1.159HisThr: 1.159 ± 1.091
1.739HisVal: 1.739 ± 0.583
1.739HisTrp: 1.739 ± 1.296
1.159HisTyr: 1.159 ± 0.571
0.0HisXaa: 0.0 ± 0.0
Ile
1.159IleAla: 1.159 ± 0.896
0.0IleCys: 0.0 ± 0.0
5.797IleAsp: 5.797 ± 2.207
2.319IleGlu: 2.319 ± 1.238
1.159IlePhe: 1.159 ± 0.58
3.478IleGly: 3.478 ± 1.256
1.159IleHis: 1.159 ± 0.797
1.159IleIle: 1.159 ± 0.91
1.739IleLys: 1.739 ± 0.882
1.739IleLeu: 1.739 ± 1.019
0.0IleMet: 0.0 ± 0.0
1.739IleAsn: 1.739 ± 0.583
2.899IlePro: 2.899 ± 0.591
0.58IleGln: 0.58 ± 0.535
4.058IleArg: 4.058 ± 2.213
1.159IleSer: 1.159 ± 0.58
2.319IleThr: 2.319 ± 1.181
4.058IleVal: 4.058 ± 1.45
1.739IleTrp: 1.739 ± 0.861
0.58IleTyr: 0.58 ± 0.907
0.0IleXaa: 0.0 ± 0.0
Lys
6.957LysAla: 6.957 ± 2.585
0.0LysCys: 0.0 ± 0.0
1.159LysAsp: 1.159 ± 0.527
2.319LysGlu: 2.319 ± 0.816
1.739LysPhe: 1.739 ± 0.693
2.319LysGly: 2.319 ± 1.287
1.739LysHis: 1.739 ± 1.009
1.159LysIle: 1.159 ± 0.571
4.638LysLys: 4.638 ± 2.059
3.478LysLeu: 3.478 ± 1.438
0.58LysMet: 0.58 ± 0.51
1.739LysAsn: 1.739 ± 1.009
2.899LysPro: 2.899 ± 0.647
1.159LysGln: 1.159 ± 0.653
4.638LysArg: 4.638 ± 2.237
3.478LysSer: 3.478 ± 1.126
3.478LysThr: 3.478 ± 1.133
1.739LysVal: 1.739 ± 0.882
1.159LysTrp: 1.159 ± 0.571
1.739LysTyr: 1.739 ± 0.829
0.0LysXaa: 0.0 ± 0.0
Leu
9.275LeuAla: 9.275 ± 1.447
0.0LeuCys: 0.0 ± 0.0
5.217LeuAsp: 5.217 ± 0.99
1.739LeuGlu: 1.739 ± 0.86
4.058LeuPhe: 4.058 ± 1.875
6.957LeuGly: 6.957 ± 2.175
3.478LeuHis: 3.478 ± 1.363
1.739LeuIle: 1.739 ± 1.664
4.638LeuLys: 4.638 ± 1.82
6.377LeuLeu: 6.377 ± 1.54
3.478LeuMet: 3.478 ± 1.06
4.638LeuAsn: 4.638 ± 1.512
8.116LeuPro: 8.116 ± 1.837
0.0LeuGln: 0.0 ± 0.0
8.116LeuArg: 8.116 ± 3.085
3.478LeuSer: 3.478 ± 1.804
5.797LeuThr: 5.797 ± 1.3
6.957LeuVal: 6.957 ± 2.272
0.0LeuTrp: 0.0 ± 0.0
2.899LeuTyr: 2.899 ± 1.046
0.0LeuXaa: 0.0 ± 0.0
Met
3.478MetAla: 3.478 ± 1.325
0.58MetCys: 0.58 ± 0.535
0.58MetAsp: 0.58 ± 0.535
1.159MetGlu: 1.159 ± 1.109
1.159MetPhe: 1.159 ± 1.034
1.739MetGly: 1.739 ± 1.232
0.58MetHis: 0.58 ± 0.455
0.58MetIle: 0.58 ± 0.455
0.58MetLys: 0.58 ± 0.67
0.58MetLeu: 0.58 ± 0.555
0.58MetMet: 0.58 ± 0.556
1.159MetAsn: 1.159 ± 0.91
1.739MetPro: 1.739 ± 0.906
0.58MetGln: 0.58 ± 0.455
1.739MetArg: 1.739 ± 0.86
2.319MetSer: 2.319 ± 1.151
1.739MetThr: 1.739 ± 0.884
0.58MetVal: 0.58 ± 0.907
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.058AsnAla: 4.058 ± 1.073
0.0AsnCys: 0.0 ± 0.0
2.899AsnAsp: 2.899 ± 1.785
1.739AsnGlu: 1.739 ± 0.738
0.58AsnPhe: 0.58 ± 0.455
2.899AsnGly: 2.899 ± 1.038
0.58AsnHis: 0.58 ± 0.535
2.319AsnIle: 2.319 ± 0.805
2.319AsnLys: 2.319 ± 1.82
1.739AsnLeu: 1.739 ± 0.813
0.0AsnMet: 0.0 ± 0.0
1.739AsnAsn: 1.739 ± 0.813
2.899AsnPro: 2.899 ± 0.896
0.58AsnGln: 0.58 ± 0.556
5.797AsnArg: 5.797 ± 1.762
2.899AsnSer: 2.899 ± 1.251
2.319AsnThr: 2.319 ± 0.956
3.478AsnVal: 3.478 ± 1.059
0.0AsnTrp: 0.0 ± 0.0
0.58AsnTyr: 0.58 ± 0.907
0.0AsnXaa: 0.0 ± 0.0
Pro
4.058ProAla: 4.058 ± 1.264
0.58ProCys: 0.58 ± 0.535
2.319ProAsp: 2.319 ± 1.279
4.638ProGlu: 4.638 ± 1.676
1.739ProPhe: 1.739 ± 0.693
5.797ProGly: 5.797 ± 2.222
2.319ProHis: 2.319 ± 0.61
2.899ProIle: 2.899 ± 1.734
2.899ProLys: 2.899 ± 1.277
5.797ProLeu: 5.797 ± 2.166
1.159ProMet: 1.159 ± 0.81
2.899ProAsn: 2.899 ± 0.825
5.797ProPro: 5.797 ± 2.496
4.058ProGln: 4.058 ± 0.611
3.478ProArg: 3.478 ± 0.957
2.319ProSer: 2.319 ± 1.151
2.899ProThr: 2.899 ± 0.647
6.957ProVal: 6.957 ± 2.16
1.739ProTrp: 1.739 ± 0.479
0.58ProTyr: 0.58 ± 0.535
0.0ProXaa: 0.0 ± 0.0
Gln
5.797GlnAla: 5.797 ± 1.993
0.58GlnCys: 0.58 ± 0.535
2.319GlnAsp: 2.319 ± 0.668
1.159GlnGlu: 1.159 ± 0.818
1.739GlnPhe: 1.739 ± 0.583
2.319GlnGly: 2.319 ± 1.238
2.899GlnHis: 2.899 ± 1.422
1.739GlnIle: 1.739 ± 0.882
1.159GlnLys: 1.159 ± 1.069
1.739GlnLeu: 1.739 ± 0.861
1.159GlnMet: 1.159 ± 0.692
1.159GlnAsn: 1.159 ± 0.692
1.739GlnPro: 1.739 ± 1.23
1.159GlnGln: 1.159 ± 0.654
2.319GlnArg: 2.319 ± 0.784
2.319GlnSer: 2.319 ± 0.784
2.319GlnThr: 2.319 ± 0.867
1.159GlnVal: 1.159 ± 0.827
0.58GlnTrp: 0.58 ± 0.535
0.58GlnTyr: 0.58 ± 0.455
0.0GlnXaa: 0.0 ± 0.0
Arg
7.536ArgAla: 7.536 ± 1.905
1.159ArgCys: 1.159 ± 0.818
5.217ArgAsp: 5.217 ± 1.159
8.116ArgGlu: 8.116 ± 3.676
1.739ArgPhe: 1.739 ± 1.041
2.899ArgGly: 2.899 ± 0.817
0.58ArgHis: 0.58 ± 0.455
2.899ArgIle: 2.899 ± 1.098
1.739ArgLys: 1.739 ± 0.861
9.855ArgLeu: 9.855 ± 2.734
2.899ArgMet: 2.899 ± 1.058
0.0ArgAsn: 0.0 ± 0.0
2.899ArgPro: 2.899 ± 1.575
4.638ArgGln: 4.638 ± 1.058
6.377ArgArg: 6.377 ± 1.684
6.377ArgSer: 6.377 ± 2.806
5.217ArgThr: 5.217 ± 1.505
5.797ArgVal: 5.797 ± 1.32
0.0ArgTrp: 0.0 ± 0.0
1.739ArgTyr: 1.739 ± 1.105
0.0ArgXaa: 0.0 ± 0.0
Ser
5.797SerAla: 5.797 ± 1.892
0.0SerCys: 0.0 ± 0.0
2.319SerAsp: 2.319 ± 0.868
2.319SerGlu: 2.319 ± 0.61
3.478SerPhe: 3.478 ± 1.321
4.058SerGly: 4.058 ± 1.549
0.58SerHis: 0.58 ± 0.535
2.899SerIle: 2.899 ± 1.003
2.319SerLys: 2.319 ± 1.251
4.058SerLeu: 4.058 ± 1.025
1.159SerMet: 1.159 ± 0.571
1.159SerAsn: 1.159 ± 0.91
2.319SerPro: 2.319 ± 1.812
3.478SerGln: 3.478 ± 1.212
4.058SerArg: 4.058 ± 1.601
2.899SerSer: 2.899 ± 1.417
4.638SerThr: 4.638 ± 2.302
3.478SerVal: 3.478 ± 1.851
0.0SerTrp: 0.0 ± 0.0
0.58SerTyr: 0.58 ± 0.556
0.0SerXaa: 0.0 ± 0.0
Thr
4.058ThrAla: 4.058 ± 1.552
0.0ThrCys: 0.0 ± 0.0
1.159ThrAsp: 1.159 ± 0.91
2.319ThrGlu: 2.319 ± 1.456
1.739ThrPhe: 1.739 ± 0.693
6.957ThrGly: 6.957 ± 1.848
1.739ThrHis: 1.739 ± 0.861
2.319ThrIle: 2.319 ± 1.028
1.739ThrLys: 1.739 ± 0.929
8.696ThrLeu: 8.696 ± 1.563
1.159ThrMet: 1.159 ± 0.663
1.739ThrAsn: 1.739 ± 1.397
5.217ThrPro: 5.217 ± 1.725
2.319ThrGln: 2.319 ± 0.668
4.058ThrArg: 4.058 ± 1.007
2.899ThrSer: 2.899 ± 0.938
1.739ThrThr: 1.739 ± 0.884
2.319ThrVal: 2.319 ± 1.066
1.159ThrTrp: 1.159 ± 0.58
2.319ThrTyr: 2.319 ± 0.868
0.0ThrXaa: 0.0 ± 0.0
Val
8.116ValAla: 8.116 ± 1.778
2.319ValCys: 2.319 ± 1.151
4.058ValAsp: 4.058 ± 1.504
1.739ValGlu: 1.739 ± 1.011
2.319ValPhe: 2.319 ± 0.837
8.116ValGly: 8.116 ± 1.774
1.159ValHis: 1.159 ± 1.111
1.159ValIle: 1.159 ± 0.91
0.58ValLys: 0.58 ± 0.556
8.116ValLeu: 8.116 ± 2.219
0.58ValMet: 0.58 ± 0.556
2.319ValAsn: 2.319 ± 0.816
5.217ValPro: 5.217 ± 1.728
2.899ValGln: 2.899 ± 1.142
3.478ValArg: 3.478 ± 1.767
5.217ValSer: 5.217 ± 1.806
3.478ValThr: 3.478 ± 1.288
3.478ValVal: 3.478 ± 1.64
2.319ValTrp: 2.319 ± 1.499
1.159ValTyr: 1.159 ± 0.527
0.0ValXaa: 0.0 ± 0.0
Trp
2.319TrpAla: 2.319 ± 1.009
0.0TrpCys: 0.0 ± 0.0
1.159TrpAsp: 1.159 ± 1.111
1.159TrpGlu: 1.159 ± 0.692
1.739TrpPhe: 1.739 ± 0.693
1.159TrpGly: 1.159 ± 0.827
0.0TrpHis: 0.0 ± 0.0
0.58TrpIle: 0.58 ± 0.535
0.0TrpLys: 0.0 ± 0.0
1.739TrpLeu: 1.739 ± 0.861
0.0TrpMet: 0.0 ± 0.0
1.739TrpAsn: 1.739 ± 0.861
1.159TrpPro: 1.159 ± 0.571
0.58TrpGln: 0.58 ± 0.455
1.159TrpArg: 1.159 ± 0.958
0.58TrpSer: 0.58 ± 0.556
1.159TrpThr: 1.159 ± 0.58
1.739TrpVal: 1.739 ± 1.292
0.0TrpTrp: 0.0 ± 0.0
0.58TrpTyr: 0.58 ± 0.535
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.319TyrAla: 2.319 ± 1.285
0.0TyrCys: 0.0 ± 0.0
1.159TyrAsp: 1.159 ± 0.827
1.159TyrGlu: 1.159 ± 0.91
0.58TyrPhe: 0.58 ± 0.455
1.159TyrGly: 1.159 ± 0.571
1.159TyrHis: 1.159 ± 1.091
1.159TyrIle: 1.159 ± 0.654
0.0TyrLys: 0.0 ± 0.0
4.058TyrLeu: 4.058 ± 1.798
0.58TyrMet: 0.58 ± 0.455
1.739TyrAsn: 1.739 ± 0.884
1.159TyrPro: 1.159 ± 1.111
0.58TyrGln: 0.58 ± 0.556
1.159TyrArg: 1.159 ± 0.973
1.159TyrSer: 1.159 ± 0.854
0.58TyrThr: 0.58 ± 0.535
1.739TyrVal: 1.739 ± 1.105
0.0TyrTrp: 0.0 ± 0.0
0.58TyrTyr: 0.58 ± 0.455
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1726 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski