Amino acid dipepetide frequency for Durio zibethinus (Durian)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.154AlaAla: 6.154 ± 0.023	1.254AlaCys: 1.254 ± 0.008	3.118AlaAsp: 3.118 ± 0.012	4.235AlaGlu: 4.235 ± 0.012	2.764AlaPhe: 2.764 ± 0.012	3.946AlaGly: 3.946 ± 0.015	1.267AlaHis: 1.267 ± 0.007	3.813AlaIle: 3.813 ± 0.015	3.871AlaLys: 3.871 ± 0.015	6.649AlaLeu: 6.649 ± 0.021	1.737AlaMet: 1.737 ± 0.009	2.655AlaAsn: 2.655 ± 0.012	2.663AlaPro: 2.663 ± 0.014	2.166AlaGln: 2.166 ± 0.011	3.249AlaArg: 3.249 ± 0.011	6.154AlaSer: 6.154 ± 0.017	3.545AlaThr: 3.545 ± 0.012	4.765AlaVal: 4.765 ± 0.016	0.744AlaTrp: 0.744 ± 0.006	1.764AlaTyr: 1.764 ± 0.009	0.002AlaXaa: 0.002 ± 0.0
Cys	0.967CysAla: 0.967 ± 0.007	0.541CysCys: 0.541 ± 0.005	0.888CysAsp: 0.888 ± 0.006	0.925CysGlu: 0.925 ± 0.007	0.92CysPhe: 0.92 ± 0.006	1.346CysGly: 1.346 ± 0.008	0.5CysHis: 0.5 ± 0.004	1.035CysIle: 1.035 ± 0.006	1.175CysLys: 1.175 ± 0.008	1.996CysLeu: 1.996 ± 0.009	0.457CysMet: 0.457 ± 0.004	0.898CysAsn: 0.898 ± 0.005	0.945CysPro: 0.945 ± 0.007	0.676CysGln: 0.676 ± 0.006	1.024CysArg: 1.024 ± 0.006	1.868CysSer: 1.868 ± 0.01	0.839CysThr: 0.839 ± 0.006	1.019CysVal: 1.019 ± 0.006	0.254CysTrp: 0.254 ± 0.003	0.551CysTyr: 0.551 ± 0.005	0.001CysXaa: 0.001 ± 0.0
Asp	3.473AspAla: 3.473 ± 0.012	0.985AspCys: 0.985 ± 0.006	3.554AspAsp: 3.554 ± 0.017	3.94AspGlu: 3.94 ± 0.015	2.354AspPhe: 2.354 ± 0.011	3.776AspGly: 3.776 ± 0.014	1.211AspHis: 1.211 ± 0.007	3.076AspIle: 3.076 ± 0.01	2.751AspLys: 2.751 ± 0.012	5.178AspLeu: 5.178 ± 0.015	1.303AspMet: 1.303 ± 0.006	2.189AspAsn: 2.189 ± 0.01	2.506AspPro: 2.506 ± 0.013	1.821AspGln: 1.821 ± 0.009	2.396AspArg: 2.396 ± 0.012	4.403AspSer: 4.403 ± 0.016	2.118AspThr: 2.118 ± 0.009	3.545AspVal: 3.545 ± 0.014	0.686AspTrp: 0.686 ± 0.005	1.532AspTyr: 1.532 ± 0.007	0.003AspXaa: 0.003 ± 0.0
Glu	4.721GluAla: 4.721 ± 0.016	0.933GluCys: 0.933 ± 0.006	3.967GluAsp: 3.967 ± 0.016	6.127GluGlu: 6.127 ± 0.027	2.416GluPhe: 2.416 ± 0.01	3.689GluGly: 3.689 ± 0.013	1.28GluHis: 1.28 ± 0.007	3.877GluIle: 3.877 ± 0.015	4.903GluLys: 4.903 ± 0.02	6.103GluLeu: 6.103 ± 0.022	1.753GluMet: 1.753 ± 0.009	3.357GluAsn: 3.357 ± 0.013	2.146GluPro: 2.146 ± 0.01	2.322GluGln: 2.322 ± 0.01	3.466GluArg: 3.466 ± 0.015	4.773GluSer: 4.773 ± 0.017	3.125GluThr: 3.125 ± 0.015	4.223GluVal: 4.223 ± 0.016	0.734GluTrp: 0.734 ± 0.005	1.633GluTyr: 1.633 ± 0.009	0.003GluXaa: 0.003 ± 0.0
Phe	2.487PheAla: 2.487 ± 0.012	0.938PheCys: 0.938 ± 0.006	2.342PheAsp: 2.342 ± 0.011	2.348PheGlu: 2.348 ± 0.009	1.981PhePhe: 1.981 ± 0.012	2.984PheGly: 2.984 ± 0.014	1.143PheHis: 1.143 ± 0.007	2.085PheIle: 2.085 ± 0.011	2.113PheLys: 2.113 ± 0.009	4.454PheLeu: 4.454 ± 0.017	0.945PheMet: 0.945 ± 0.006	1.813PheAsn: 1.813 ± 0.009	2.167PhePro: 2.167 ± 0.011	1.661PheGln: 1.661 ± 0.008	2.013PheArg: 2.013 ± 0.009	4.238PheSer: 4.238 ± 0.014	1.937PheThr: 1.937 ± 0.01	2.669PheVal: 2.669 ± 0.01	0.572PheTrp: 0.572 ± 0.005	1.274PheTyr: 1.274 ± 0.008	0.002PheXaa: 0.002 ± 0.0
Gly	3.746GlyAla: 3.746 ± 0.016	1.286GlyCys: 1.286 ± 0.007	3.282GlyAsp: 3.282 ± 0.013	3.633GlyGlu: 3.633 ± 0.015	3.075GlyPhe: 3.075 ± 0.012	4.876GlyGly: 4.876 ± 0.026	1.544GlyHis: 1.544 ± 0.008	3.625GlyIle: 3.625 ± 0.012	4.091GlyLys: 4.091 ± 0.012	5.894GlyLeu: 5.894 ± 0.017	1.497GlyMet: 1.497 ± 0.008	3.295GlyAsn: 3.295 ± 0.014	2.396GlyPro: 2.396 ± 0.01	2.175GlyGln: 2.175 ± 0.011	3.474GlyArg: 3.474 ± 0.014	6.217GlySer: 6.217 ± 0.02	3.166GlyThr: 3.166 ± 0.014	3.967GlyVal: 3.967 ± 0.012	0.849GlyTrp: 0.849 ± 0.006	1.969GlyTyr: 1.969 ± 0.011	0.003GlyXaa: 0.003 ± 0.0
His	1.424HisAla: 1.424 ± 0.007	0.529HisCys: 0.529 ± 0.005	1.183HisAsp: 1.183 ± 0.007	1.309HisGlu: 1.309 ± 0.007	1.074HisPhe: 1.074 ± 0.007	1.703HisGly: 1.703 ± 0.008	0.903HisHis: 0.903 ± 0.008	1.212HisIle: 1.212 ± 0.008	1.152HisLys: 1.152 ± 0.007	2.499HisLeu: 2.499 ± 0.01	0.547HisMet: 0.547 ± 0.004	0.962HisAsn: 0.962 ± 0.007	1.369HisPro: 1.369 ± 0.008	1.051HisGln: 1.051 ± 0.007	1.341HisArg: 1.341 ± 0.008	2.029HisSer: 2.029 ± 0.01	0.893HisThr: 0.893 ± 0.006	1.53HisVal: 1.53 ± 0.009	0.297HisTrp: 0.297 ± 0.003	0.705HisTyr: 0.705 ± 0.005	0.001HisXaa: 0.001 ± 0.0
Ile	3.613IleAla: 3.613 ± 0.012	1.161IleCys: 1.161 ± 0.007	2.909IleAsp: 2.909 ± 0.011	3.305IleGlu: 3.305 ± 0.012	2.329IlePhe: 2.329 ± 0.011	3.417IleGly: 3.417 ± 0.014	1.288IleHis: 1.288 ± 0.008	2.842IleIle: 2.842 ± 0.012	2.981IleLys: 2.981 ± 0.012	5.36IleLeu: 5.36 ± 0.017	1.121IleMet: 1.121 ± 0.006	2.245IleAsn: 2.245 ± 0.008	3.044IlePro: 3.044 ± 0.015	2.07IleGln: 2.07 ± 0.01	2.639IleArg: 2.639 ± 0.012	5.072IleSer: 5.072 ± 0.014	2.522IleThr: 2.522 ± 0.01	3.385IleVal: 3.385 ± 0.013	0.694IleTrp: 0.694 ± 0.005	1.493IleTyr: 1.493 ± 0.009	0.002IleXaa: 0.002 ± 0.0
Lys	4.047LysAla: 4.047 ± 0.014	0.984LysCys: 0.984 ± 0.007	3.288LysAsp: 3.288 ± 0.013	4.782LysGlu: 4.782 ± 0.021	2.244LysPhe: 2.244 ± 0.011	3.62LysGly: 3.62 ± 0.013	1.372LysHis: 1.372 ± 0.008	3.303LysIle: 3.303 ± 0.012	4.624LysLys: 4.624 ± 0.018	6.171LysLeu: 6.171 ± 0.019	1.5LysMet: 1.5 ± 0.008	2.751LysAsn: 2.751 ± 0.012	2.752LysPro: 2.752 ± 0.014	2.421LysGln: 2.421 ± 0.012	3.611LysArg: 3.611 ± 0.012	4.811LysSer: 4.811 ± 0.017	2.823LysThr: 2.823 ± 0.011	3.864LysVal: 3.864 ± 0.014	0.778LysTrp: 0.778 ± 0.005	1.599LysTyr: 1.599 ± 0.008	0.003LysXaa: 0.003 ± 0.0
Leu	6.533LeuAla: 6.533 ± 0.018	1.884LeuCys: 1.884 ± 0.01	5.241LeuAsp: 5.241 ± 0.016	6.733LeuGlu: 6.733 ± 0.024	3.877LeuPhe: 3.877 ± 0.014	5.754LeuGly: 5.754 ± 0.015	2.637LeuHis: 2.637 ± 0.01	4.646LeuIle: 4.646 ± 0.016	6.49LeuLys: 6.49 ± 0.022	10.305LeuLeu: 10.305 ± 0.031	2.139LeuMet: 2.139 ± 0.01	4.189LeuAsn: 4.189 ± 0.014	5.237LeuPro: 5.237 ± 0.016	4.668LeuGln: 4.668 ± 0.018	5.416LeuArg: 5.416 ± 0.019	9.163LeuSer: 9.163 ± 0.025	4.464LeuThr: 4.464 ± 0.017	6.278LeuVal: 6.278 ± 0.019	1.124LeuTrp: 1.124 ± 0.007	2.557LeuTyr: 2.557 ± 0.013	0.004LeuXaa: 0.004 ± 0.0
Met	2.059MetAla: 2.059 ± 0.008	0.313MetCys: 0.313 ± 0.004	1.434MetAsp: 1.434 ± 0.007	2.017MetGlu: 2.017 ± 0.009	0.818MetPhe: 0.818 ± 0.005	1.567MetGly: 1.567 ± 0.009	0.554MetHis: 0.554 ± 0.005	1.172MetIle: 1.172 ± 0.007	1.577MetLys: 1.577 ± 0.009	2.239MetLeu: 2.239 ± 0.01	0.637MetMet: 0.637 ± 0.005	1.024MetAsn: 1.024 ± 0.007	1.078MetPro: 1.078 ± 0.007	1.012MetGln: 1.012 ± 0.007	1.158MetArg: 1.158 ± 0.007	1.741MetSer: 1.741 ± 0.009	1.011MetThr: 1.011 ± 0.007	1.615MetVal: 1.615 ± 0.009	0.255MetTrp: 0.255 ± 0.003	0.545MetTyr: 0.545 ± 0.005	0.001MetXaa: 0.001 ± 0.0
Asn	2.763AsnAla: 2.763 ± 0.01	0.92AsnCys: 0.92 ± 0.007	2.186AsnAsp: 2.186 ± 0.009	2.691AsnGlu: 2.691 ± 0.012	2.05AsnPhe: 2.05 ± 0.01	3.378AsnGly: 3.378 ± 0.014	1.128AsnHis: 1.128 ± 0.007	2.557AsnIle: 2.557 ± 0.011	2.454AsnLys: 2.454 ± 0.011	5.015AsnLeu: 5.015 ± 0.023	1.133AsnMet: 1.133 ± 0.006	2.442AsnAsn: 2.442 ± 0.015	2.352AsnPro: 2.352 ± 0.01	1.89AsnGln: 1.89 ± 0.009	2.046AsnArg: 2.046 ± 0.009	4.191AsnSer: 4.191 ± 0.016	1.862AsnThr: 1.862 ± 0.009	2.802AsnVal: 2.802 ± 0.01	0.582AsnTrp: 0.582 ± 0.005	1.299AsnTyr: 1.299 ± 0.008	0.002AsnXaa: 0.002 ± 0.0
Pro	2.965ProAla: 2.965 ± 0.014	0.796ProCys: 0.796 ± 0.006	2.406ProAsp: 2.406 ± 0.01	3.104ProGlu: 3.104 ± 0.012	2.032ProPhe: 2.032 ± 0.009	2.681ProGly: 2.681 ± 0.013	1.062ProHis: 1.062 ± 0.007	2.348ProIle: 2.348 ± 0.01	2.751ProLys: 2.751 ± 0.013	4.336ProLeu: 4.336 ± 0.012	0.976ProMet: 0.976 ± 0.006	2.299ProAsn: 2.299 ± 0.01	3.664ProPro: 3.664 ± 0.038	1.881ProGln: 1.881 ± 0.011	2.31ProArg: 2.31 ± 0.01	5.228ProSer: 5.228 ± 0.019	2.556ProThr: 2.556 ± 0.012	3.066ProVal: 3.066 ± 0.011	0.585ProTrp: 0.585 ± 0.005	1.299ProTyr: 1.299 ± 0.009	0.003ProXaa: 0.003 ± 0.0
Gln	2.499GlnAla: 2.499 ± 0.011	0.62GlnCys: 0.62 ± 0.005	1.756GlnAsp: 1.756 ± 0.008	2.515GlnGlu: 2.515 ± 0.011	1.469GlnPhe: 1.469 ± 0.007	2.175GlnGly: 2.175 ± 0.01	1.002GlnHis: 1.002 ± 0.006	2.128GlnIle: 2.128 ± 0.01	2.463GlnLys: 2.463 ± 0.01	3.991GlnLeu: 3.991 ± 0.015	1.013GlnMet: 1.013 ± 0.007	1.97GlnAsn: 1.97 ± 0.01	1.835GlnPro: 1.835 ± 0.01	2.368GlnGln: 2.368 ± 0.026	2.19GlnArg: 2.19 ± 0.01	3.14GlnSer: 3.14 ± 0.012	1.777GlnThr: 1.777 ± 0.009	2.454GlnVal: 2.454 ± 0.011	0.472GlnTrp: 0.472 ± 0.005	0.969GlnTyr: 0.969 ± 0.006	0.002GlnXaa: 0.002 ± 0.0
Arg	3.134ArgAla: 3.134 ± 0.012	0.982ArgCys: 0.982 ± 0.007	2.636ArgAsp: 2.636 ± 0.012	3.34ArgGlu: 3.34 ± 0.017	2.162ArgPhe: 2.162 ± 0.009	3.055ArgGly: 3.055 ± 0.014	1.264ArgHis: 1.264 ± 0.007	2.87ArgIle: 2.87 ± 0.01	3.858ArgLys: 3.858 ± 0.014	5.034ArgLeu: 5.034 ± 0.017	1.289ArgMet: 1.289 ± 0.006	2.522ArgAsn: 2.522 ± 0.009	2.257ArgPro: 2.257 ± 0.011	1.946ArgGln: 1.946 ± 0.01	3.703ArgArg: 3.703 ± 0.018	4.344ArgSer: 4.344 ± 0.019	2.39ArgThr: 2.39 ± 0.011	3.126ArgVal: 3.126 ± 0.011	0.734ArgTrp: 0.734 ± 0.006	1.438ArgTyr: 1.438 ± 0.007	0.003ArgXaa: 0.003 ± 0.0
Ser	5.425SerAla: 5.425 ± 0.017	1.793SerCys: 1.793 ± 0.01	4.543SerAsp: 4.543 ± 0.014	5.053SerGlu: 5.053 ± 0.019	4.162SerPhe: 4.162 ± 0.015	6.117SerGly: 6.117 ± 0.02	2.073SerHis: 2.073 ± 0.009	4.721SerIle: 4.721 ± 0.014	5.148SerLys: 5.148 ± 0.016	9.206SerLeu: 9.206 ± 0.027	2.147SerMet: 2.147 ± 0.009	4.41SerAsn: 4.41 ± 0.018	4.587SerPro: 4.587 ± 0.022	3.288SerGln: 3.288 ± 0.013	4.553SerArg: 4.553 ± 0.018	11.541SerSer: 11.541 ± 0.036	4.684SerThr: 4.684 ± 0.016	5.343SerVal: 5.343 ± 0.018	1.162SerTrp: 1.162 ± 0.008	2.345SerTyr: 2.345 ± 0.011	0.003SerXaa: 0.003 ± 0.0
Thr	3.398ThrAla: 3.398 ± 0.014	0.92ThrCys: 0.92 ± 0.006	2.256ThrAsp: 2.256 ± 0.008	2.809ThrGlu: 2.809 ± 0.014	1.998ThrPhe: 1.998 ± 0.009	3.197ThrGly: 3.197 ± 0.012	0.962ThrHis: 0.962 ± 0.007	2.68ThrIle: 2.68 ± 0.012	2.638ThrLys: 2.638 ± 0.01	4.571ThrLeu: 4.571 ± 0.015	1.109ThrMet: 1.109 ± 0.006	2.04ThrAsn: 2.04 ± 0.01	2.463ThrPro: 2.463 ± 0.012	1.558ThrGln: 1.558 ± 0.008	2.248ThrArg: 2.248 ± 0.01	4.665ThrSer: 4.665 ± 0.013	2.722ThrThr: 2.722 ± 0.012	3.233ThrVal: 3.233 ± 0.013	0.589ThrTrp: 0.589 ± 0.005	1.3ThrTyr: 1.3 ± 0.007	0.002ThrXaa: 0.002 ± 0.0
Val	4.677ValAla: 4.677 ± 0.018	1.115ValCys: 1.115 ± 0.007	3.64ValAsp: 3.64 ± 0.012	4.349ValGlu: 4.349 ± 0.014	2.634ValPhe: 2.634 ± 0.012	4.037ValGly: 4.037 ± 0.013	1.494ValHis: 1.494 ± 0.008	3.361ValIle: 3.361 ± 0.012	3.874ValLys: 3.874 ± 0.016	6.295ValLeu: 6.295 ± 0.017	1.464ValMet: 1.464 ± 0.008	2.706ValAsn: 2.706 ± 0.011	3.155ValPro: 3.155 ± 0.012	2.371ValGln: 2.371 ± 0.01	3.015ValArg: 3.015 ± 0.014	5.475ValSer: 5.475 ± 0.015	3.126ValThr: 3.126 ± 0.013	4.52ValVal: 4.52 ± 0.016	0.727ValTrp: 0.727 ± 0.005	1.827ValTyr: 1.827 ± 0.009	0.003ValXaa: 0.003 ± 0.0
Trp	0.724TrpAla: 0.724 ± 0.006	0.23TrpCys: 0.23 ± 0.003	0.691TrpAsp: 0.691 ± 0.005	0.759TrpGlu: 0.759 ± 0.006	0.53TrpPhe: 0.53 ± 0.005	0.682TrpGly: 0.682 ± 0.005	0.31TrpHis: 0.31 ± 0.004	0.696TrpIle: 0.696 ± 0.005	0.927TrpLys: 0.927 ± 0.006	1.23TrpLeu: 1.23 ± 0.008	0.336TrpMet: 0.336 ± 0.004	0.68TrpAsn: 0.68 ± 0.005	0.486TrpPro: 0.486 ± 0.005	0.471TrpGln: 0.471 ± 0.004	0.811TrpArg: 0.811 ± 0.006	0.954TrpSer: 0.954 ± 0.006	0.609TrpThr: 0.609 ± 0.005	0.763TrpVal: 0.763 ± 0.005	0.227TrpTrp: 0.227 ± 0.003	0.33TrpTyr: 0.33 ± 0.004	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.705TyrAla: 1.705 ± 0.008	0.636TyrCys: 0.636 ± 0.005	1.479TyrAsp: 1.479 ± 0.009	1.573TyrGlu: 1.573 ± 0.008	1.274TyrPhe: 1.274 ± 0.008	2.059TyrGly: 2.059 ± 0.011	0.718TyrHis: 0.718 ± 0.005	1.445TyrIle: 1.445 ± 0.008	1.503TyrLys: 1.503 ± 0.01	2.808TyrLeu: 2.808 ± 0.012	0.722TyrMet: 0.722 ± 0.005	1.292TyrAsn: 1.292 ± 0.008	1.244TyrPro: 1.244 ± 0.009	0.991TyrGln: 0.991 ± 0.005	1.424TyrArg: 1.424 ± 0.007	2.294TyrSer: 2.294 ± 0.01	1.185TyrThr: 1.185 ± 0.007	1.697TyrVal: 1.697 ± 0.009	0.38TyrTrp: 0.38 ± 0.004	0.946TyrTyr: 0.946 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.003XaaGlu: 0.003 ± 0.0	0.003XaaPhe: 0.003 ± 0.0	0.003XaaGly: 0.003 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.002XaaIle: 0.002 ± 0.0	0.003XaaLys: 0.003 ± 0.0	0.004XaaLeu: 0.004 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.003XaaAsn: 0.003 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.003XaaSer: 0.003 ± 0.0	0.002XaaThr: 0.002 ± 0.0	0.003XaaVal: 0.003 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 53026 proteins (26388952 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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