Amino acid dipepetide frequency for Xanthomonas virus CP1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.971AlaAla: 11.971 ± 1.372
0.476AlaCys: 0.476 ± 0.212
6.263AlaAsp: 6.263 ± 0.772
6.263AlaGlu: 6.263 ± 0.713
3.488AlaPhe: 3.488 ± 0.534
9.355AlaGly: 9.355 ± 1.073
2.299AlaHis: 2.299 ± 0.471
4.281AlaIle: 4.281 ± 0.719
5.391AlaLys: 5.391 ± 0.933
9.355AlaLeu: 9.355 ± 0.945
3.171AlaMet: 3.171 ± 0.666
3.726AlaAsn: 3.726 ± 0.475
3.092AlaPro: 3.092 ± 0.501
5.708AlaGln: 5.708 ± 0.897
6.58AlaArg: 6.58 ± 0.608
6.501AlaSer: 6.501 ± 0.943
7.531AlaThr: 7.531 ± 0.85
6.342AlaVal: 6.342 ± 0.614
2.061AlaTrp: 2.061 ± 0.346
3.171AlaTyr: 3.171 ± 0.556
0.0AlaXaa: 0.0 ± 0.0
Cys
0.951CysAla: 0.951 ± 0.459
0.238CysCys: 0.238 ± 0.138
0.555CysAsp: 0.555 ± 0.245
0.396CysGlu: 0.396 ± 0.186
0.238CysPhe: 0.238 ± 0.141
1.348CysGly: 1.348 ± 0.349
0.238CysHis: 0.238 ± 0.147
0.476CysIle: 0.476 ± 0.183
0.634CysLys: 0.634 ± 0.243
0.634CysLeu: 0.634 ± 0.247
0.317CysMet: 0.317 ± 0.157
0.634CysAsn: 0.634 ± 0.227
0.713CysPro: 0.713 ± 0.412
0.634CysGln: 0.634 ± 0.226
0.555CysArg: 0.555 ± 0.226
0.713CysSer: 0.713 ± 0.26
0.713CysThr: 0.713 ± 0.254
0.555CysVal: 0.555 ± 0.181
0.159CysTrp: 0.159 ± 0.105
0.476CysTyr: 0.476 ± 0.184
0.0CysXaa: 0.0 ± 0.0
Asp
5.391AspAla: 5.391 ± 0.619
0.476AspCys: 0.476 ± 0.18
1.903AspAsp: 1.903 ± 0.398
3.805AspGlu: 3.805 ± 0.53
2.061AspPhe: 2.061 ± 0.436
4.043AspGly: 4.043 ± 0.621
1.031AspHis: 1.031 ± 0.305
3.092AspIle: 3.092 ± 0.433
2.14AspLys: 2.14 ± 0.39
4.757AspLeu: 4.757 ± 0.544
0.793AspMet: 0.793 ± 0.235
1.823AspAsn: 1.823 ± 0.333
2.695AspPro: 2.695 ± 0.481
1.982AspGln: 1.982 ± 0.378
2.933AspArg: 2.933 ± 0.436
3.171AspSer: 3.171 ± 0.626
3.567AspThr: 3.567 ± 0.505
3.964AspVal: 3.964 ± 0.619
1.506AspTrp: 1.506 ± 0.398
1.823AspTyr: 1.823 ± 0.35
0.0AspXaa: 0.0 ± 0.0
Glu
5.866GluAla: 5.866 ± 0.798
0.872GluCys: 0.872 ± 0.24
2.537GluAsp: 2.537 ± 0.425
4.202GluGlu: 4.202 ± 0.668
2.22GluPhe: 2.22 ± 0.603
4.519GluGly: 4.519 ± 0.535
1.031GluHis: 1.031 ± 0.33
2.299GluIle: 2.299 ± 0.426
2.14GluLys: 2.14 ± 0.52
6.342GluLeu: 6.342 ± 0.663
1.665GluMet: 1.665 ± 0.375
2.22GluAsn: 2.22 ± 0.333
1.427GluPro: 1.427 ± 0.355
2.537GluGln: 2.537 ± 0.568
2.775GluArg: 2.775 ± 0.438
3.726GluSer: 3.726 ± 0.513
2.854GluThr: 2.854 ± 0.423
4.598GluVal: 4.598 ± 0.58
0.951GluTrp: 0.951 ± 0.381
1.348GluTyr: 1.348 ± 0.373
0.0GluXaa: 0.0 ± 0.0
Phe
2.458PheAla: 2.458 ± 0.377
0.555PheCys: 0.555 ± 0.24
2.854PheAsp: 2.854 ± 0.522
1.268PheGlu: 1.268 ± 0.383
0.872PhePhe: 0.872 ± 0.241
1.982PheGly: 1.982 ± 0.347
0.793PheHis: 0.793 ± 0.262
1.823PheIle: 1.823 ± 0.354
1.427PheLys: 1.427 ± 0.332
2.537PheLeu: 2.537 ± 0.44
0.476PheMet: 0.476 ± 0.21
1.268PheAsn: 1.268 ± 0.364
1.189PhePro: 1.189 ± 0.262
0.872PheGln: 0.872 ± 0.261
1.268PheArg: 1.268 ± 0.379
2.14PheSer: 2.14 ± 0.388
1.744PheThr: 1.744 ± 0.389
2.537PheVal: 2.537 ± 0.514
0.476PheTrp: 0.476 ± 0.163
0.793PheTyr: 0.793 ± 0.27
0.0PheXaa: 0.0 ± 0.0
Gly
7.611GlyAla: 7.611 ± 0.926
0.713GlyCys: 0.713 ± 0.425
4.44GlyAsp: 4.44 ± 0.678
5.074GlyGlu: 5.074 ± 0.658
2.378GlyPhe: 2.378 ± 0.485
7.293GlyGly: 7.293 ± 0.802
1.11GlyHis: 1.11 ± 0.328
3.488GlyIle: 3.488 ± 0.463
6.58GlyLys: 6.58 ± 0.826
6.659GlyLeu: 6.659 ± 0.691
2.14GlyMet: 2.14 ± 0.421
4.44GlyAsn: 4.44 ± 0.991
2.061GlyPro: 2.061 ± 0.411
3.488GlyGln: 3.488 ± 0.733
5.153GlyArg: 5.153 ± 0.713
5.787GlySer: 5.787 ± 0.643
4.598GlyThr: 4.598 ± 0.78
7.531GlyVal: 7.531 ± 0.749
1.11GlyTrp: 1.11 ± 0.267
3.488GlyTyr: 3.488 ± 0.604
0.0GlyXaa: 0.0 ± 0.0
His
1.189HisAla: 1.189 ± 0.271
0.634HisCys: 0.634 ± 0.231
0.634HisAsp: 0.634 ± 0.183
1.031HisGlu: 1.031 ± 0.34
0.317HisPhe: 0.317 ± 0.198
1.348HisGly: 1.348 ± 0.67
0.793HisHis: 0.793 ± 0.266
1.268HisIle: 1.268 ± 0.424
1.427HisLys: 1.427 ± 0.481
1.823HisLeu: 1.823 ± 0.478
0.713HisMet: 0.713 ± 0.243
1.031HisAsn: 1.031 ± 0.331
0.872HisPro: 0.872 ± 0.32
0.634HisGln: 0.634 ± 0.216
1.903HisArg: 1.903 ± 0.426
1.348HisSer: 1.348 ± 0.401
1.268HisThr: 1.268 ± 0.394
1.11HisVal: 1.11 ± 0.376
0.238HisTrp: 0.238 ± 0.133
0.555HisTyr: 0.555 ± 0.235
0.0HisXaa: 0.0 ± 0.0
Ile
4.598IleAla: 4.598 ± 0.614
0.396IleCys: 0.396 ± 0.164
2.616IleAsp: 2.616 ± 0.36
2.933IleGlu: 2.933 ± 0.335
0.793IlePhe: 0.793 ± 0.279
3.092IleGly: 3.092 ± 0.522
0.476IleHis: 0.476 ± 0.226
1.268IleIle: 1.268 ± 0.349
2.695IleLys: 2.695 ± 0.486
2.933IleLeu: 2.933 ± 0.576
0.396IleMet: 0.396 ± 0.163
2.061IleAsn: 2.061 ± 0.477
1.744IlePro: 1.744 ± 0.387
1.823IleGln: 1.823 ± 0.4
3.013IleArg: 3.013 ± 0.434
4.122IleSer: 4.122 ± 0.624
3.885IleThr: 3.885 ± 0.46
1.506IleVal: 1.506 ± 0.43
0.317IleTrp: 0.317 ± 0.166
1.665IleTyr: 1.665 ± 0.402
0.0IleXaa: 0.0 ± 0.0
Lys
6.025LysAla: 6.025 ± 0.551
0.634LysCys: 0.634 ± 0.41
3.092LysAsp: 3.092 ± 0.512
2.061LysGlu: 2.061 ± 0.401
1.348LysPhe: 1.348 ± 0.326
3.726LysGly: 3.726 ± 0.713
1.268LysHis: 1.268 ± 0.493
2.458LysIle: 2.458 ± 0.429
2.14LysLys: 2.14 ± 0.53
4.44LysLeu: 4.44 ± 0.576
1.268LysMet: 1.268 ± 0.27
1.665LysAsn: 1.665 ± 0.299
1.427LysPro: 1.427 ± 0.424
2.299LysGln: 2.299 ± 0.695
3.33LysArg: 3.33 ± 0.723
2.22LysSer: 2.22 ± 0.392
3.488LysThr: 3.488 ± 0.48
3.409LysVal: 3.409 ± 0.515
1.11LysTrp: 1.11 ± 0.269
2.22LysTyr: 2.22 ± 0.455
0.0LysXaa: 0.0 ± 0.0
Leu
10.544LeuAla: 10.544 ± 0.893
1.268LeuCys: 1.268 ± 0.327
4.281LeuAsp: 4.281 ± 0.4
4.44LeuGlu: 4.44 ± 0.612
1.506LeuPhe: 1.506 ± 0.35
7.293LeuGly: 7.293 ± 0.849
2.299LeuHis: 2.299 ± 0.375
2.22LeuIle: 2.22 ± 0.447
3.33LeuLys: 3.33 ± 0.48
7.769LeuLeu: 7.769 ± 1.04
1.744LeuMet: 1.744 ± 0.349
3.567LeuAsn: 3.567 ± 0.523
3.726LeuPro: 3.726 ± 0.771
4.994LeuGln: 4.994 ± 0.626
6.184LeuArg: 6.184 ± 0.655
7.214LeuSer: 7.214 ± 0.736
6.263LeuThr: 6.263 ± 0.805
4.44LeuVal: 4.44 ± 0.605
1.11LeuTrp: 1.11 ± 0.261
1.982LeuTyr: 1.982 ± 0.398
0.0LeuXaa: 0.0 ± 0.0
Met
2.537MetAla: 2.537 ± 0.441
0.159MetCys: 0.159 ± 0.124
2.22MetAsp: 2.22 ± 0.549
1.348MetGlu: 1.348 ± 0.471
0.713MetPhe: 0.713 ± 0.263
1.506MetGly: 1.506 ± 0.325
0.634MetHis: 0.634 ± 0.241
0.476MetIle: 0.476 ± 0.204
0.872MetLys: 0.872 ± 0.272
2.061MetLeu: 2.061 ± 0.37
0.159MetMet: 0.159 ± 0.117
0.555MetAsn: 0.555 ± 0.211
0.793MetPro: 0.793 ± 0.248
1.744MetGln: 1.744 ± 0.307
1.665MetArg: 1.665 ± 0.329
2.14MetSer: 2.14 ± 0.399
1.506MetThr: 1.506 ± 0.26
2.061MetVal: 2.061 ± 0.338
0.317MetTrp: 0.317 ± 0.15
0.713MetTyr: 0.713 ± 0.29
0.0MetXaa: 0.0 ± 0.0
Asn
5.391AsnAla: 5.391 ± 0.953
0.238AsnCys: 0.238 ± 0.15
1.189AsnAsp: 1.189 ± 0.42
1.427AsnGlu: 1.427 ± 0.286
1.427AsnPhe: 1.427 ± 0.388
3.488AsnGly: 3.488 ± 0.738
0.555AsnHis: 0.555 ± 0.208
2.14AsnIle: 2.14 ± 0.357
1.823AsnLys: 1.823 ± 0.355
3.25AsnLeu: 3.25 ± 0.41
1.348AsnMet: 1.348 ± 0.354
2.299AsnAsn: 2.299 ± 0.463
2.14AsnPro: 2.14 ± 0.385
1.665AsnGln: 1.665 ± 0.369
2.14AsnArg: 2.14 ± 0.464
3.33AsnSer: 3.33 ± 0.569
2.378AsnThr: 2.378 ± 0.486
2.061AsnVal: 2.061 ± 0.368
1.031AsnTrp: 1.031 ± 0.259
0.951AsnTyr: 0.951 ± 0.27
0.0AsnXaa: 0.0 ± 0.0
Pro
3.885ProAla: 3.885 ± 0.528
0.555ProCys: 0.555 ± 0.198
2.458ProAsp: 2.458 ± 0.416
3.171ProGlu: 3.171 ± 0.465
0.793ProPhe: 0.793 ± 0.231
3.488ProGly: 3.488 ± 0.571
0.476ProHis: 0.476 ± 0.167
1.348ProIle: 1.348 ± 0.31
2.378ProLys: 2.378 ± 0.506
2.933ProLeu: 2.933 ± 0.515
0.793ProMet: 0.793 ± 0.261
1.506ProAsn: 1.506 ± 0.269
1.586ProPro: 1.586 ± 0.466
1.268ProGln: 1.268 ± 0.398
1.665ProArg: 1.665 ± 0.344
2.616ProSer: 2.616 ± 0.501
2.537ProThr: 2.537 ± 0.4
3.25ProVal: 3.25 ± 0.449
0.555ProTrp: 0.555 ± 0.212
0.872ProTyr: 0.872 ± 0.285
0.0ProXaa: 0.0 ± 0.0
Gln
5.47GlnAla: 5.47 ± 0.9
0.317GlnCys: 0.317 ± 0.164
1.982GlnAsp: 1.982 ± 0.415
2.299GlnGlu: 2.299 ± 0.42
1.189GlnPhe: 1.189 ± 0.284
4.36GlnGly: 4.36 ± 0.626
0.634GlnHis: 0.634 ± 0.216
2.933GlnIle: 2.933 ± 0.603
1.031GlnLys: 1.031 ± 0.368
5.47GlnLeu: 5.47 ± 0.59
1.348GlnMet: 1.348 ± 0.341
1.427GlnAsn: 1.427 ± 0.308
1.427GlnPro: 1.427 ± 0.312
1.823GlnGln: 1.823 ± 0.449
3.488GlnArg: 3.488 ± 0.6
2.695GlnSer: 2.695 ± 0.563
1.823GlnThr: 1.823 ± 0.403
3.171GlnVal: 3.171 ± 0.62
0.476GlnTrp: 0.476 ± 0.156
1.744GlnTyr: 1.744 ± 0.373
0.0GlnXaa: 0.0 ± 0.0
Arg
5.708ArgAla: 5.708 ± 0.917
0.793ArgCys: 0.793 ± 0.304
2.616ArgAsp: 2.616 ± 0.515
4.677ArgGlu: 4.677 ± 0.681
1.348ArgPhe: 1.348 ± 0.312
3.885ArgGly: 3.885 ± 0.66
1.348ArgHis: 1.348 ± 0.373
2.933ArgIle: 2.933 ± 0.456
3.647ArgLys: 3.647 ± 0.759
5.312ArgLeu: 5.312 ± 0.709
2.061ArgMet: 2.061 ± 0.356
2.616ArgAsn: 2.616 ± 0.386
1.982ArgPro: 1.982 ± 0.412
2.299ArgGln: 2.299 ± 0.43
2.378ArgArg: 2.378 ± 0.551
3.726ArgSer: 3.726 ± 0.456
3.33ArgThr: 3.33 ± 0.521
4.915ArgVal: 4.915 ± 0.926
1.268ArgTrp: 1.268 ± 0.35
2.537ArgTyr: 2.537 ± 0.451
0.0ArgXaa: 0.0 ± 0.0
Ser
9.038SerAla: 9.038 ± 1.179
0.872SerCys: 0.872 ± 0.311
3.33SerAsp: 3.33 ± 0.479
2.22SerGlu: 2.22 ± 0.487
2.458SerPhe: 2.458 ± 0.345
7.531SerGly: 7.531 ± 0.943
0.872SerHis: 0.872 ± 0.349
3.013SerIle: 3.013 ± 0.481
3.409SerLys: 3.409 ± 0.639
6.025SerLeu: 6.025 ± 0.777
1.427SerMet: 1.427 ± 0.296
2.22SerAsn: 2.22 ± 0.596
3.25SerPro: 3.25 ± 0.502
2.854SerGln: 2.854 ± 0.458
3.092SerArg: 3.092 ± 0.69
4.36SerSer: 4.36 ± 0.962
4.836SerThr: 4.836 ± 0.61
5.629SerVal: 5.629 ± 0.582
1.11SerTrp: 1.11 ± 0.284
1.665SerTyr: 1.665 ± 0.42
0.0SerXaa: 0.0 ± 0.0
Thr
6.739ThrAla: 6.739 ± 0.809
0.555ThrCys: 0.555 ± 0.244
3.013ThrAsp: 3.013 ± 0.515
3.013ThrGlu: 3.013 ± 0.5
1.665ThrPhe: 1.665 ± 0.348
7.848ThrGly: 7.848 ± 0.904
1.11ThrHis: 1.11 ± 0.352
2.537ThrIle: 2.537 ± 0.369
3.25ThrLys: 3.25 ± 0.466
5.312ThrLeu: 5.312 ± 0.673
1.031ThrMet: 1.031 ± 0.31
2.695ThrAsn: 2.695 ± 0.354
2.616ThrPro: 2.616 ± 0.535
2.378ThrGln: 2.378 ± 0.329
3.171ThrArg: 3.171 ± 0.409
5.391ThrSer: 5.391 ± 0.794
4.122ThrThr: 4.122 ± 0.699
4.122ThrVal: 4.122 ± 0.975
0.872ThrTrp: 0.872 ± 0.296
1.506ThrTyr: 1.506 ± 0.403
0.0ThrXaa: 0.0 ± 0.0
Val
7.135ValAla: 7.135 ± 1.051
0.555ValCys: 0.555 ± 0.236
3.488ValAsp: 3.488 ± 0.433
4.36ValGlu: 4.36 ± 0.608
2.458ValPhe: 2.458 ± 0.342
5.232ValGly: 5.232 ± 0.651
2.061ValHis: 2.061 ± 0.79
2.299ValIle: 2.299 ± 0.355
3.171ValLys: 3.171 ± 0.447
4.757ValLeu: 4.757 ± 0.665
1.823ValMet: 1.823 ± 0.422
2.616ValAsn: 2.616 ± 0.426
3.25ValPro: 3.25 ± 0.497
3.964ValGln: 3.964 ± 0.6
4.281ValArg: 4.281 ± 0.628
4.519ValSer: 4.519 ± 0.68
3.885ValThr: 3.885 ± 0.622
6.025ValVal: 6.025 ± 0.817
2.061ValTrp: 2.061 ± 0.391
2.775ValTyr: 2.775 ± 0.52
0.0ValXaa: 0.0 ± 0.0
Trp
1.744TrpAla: 1.744 ± 0.306
0.476TrpCys: 0.476 ± 0.168
1.189TrpAsp: 1.189 ± 0.321
0.713TrpGlu: 0.713 ± 0.241
0.793TrpPhe: 0.793 ± 0.273
1.348TrpGly: 1.348 ± 0.252
0.317TrpHis: 0.317 ± 0.193
0.238TrpIle: 0.238 ± 0.132
0.793TrpLys: 0.793 ± 0.207
1.744TrpLeu: 1.744 ± 0.428
0.634TrpMet: 0.634 ± 0.257
0.713TrpAsn: 0.713 ± 0.193
0.713TrpPro: 0.713 ± 0.243
0.872TrpGln: 0.872 ± 0.229
1.189TrpArg: 1.189 ± 0.234
1.11TrpSer: 1.11 ± 0.28
0.872TrpThr: 0.872 ± 0.261
1.11TrpVal: 1.11 ± 0.351
0.238TrpTrp: 0.238 ± 0.124
0.555TrpTyr: 0.555 ± 0.18
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.775TyrAla: 2.775 ± 0.405
0.396TyrCys: 0.396 ± 0.206
2.299TyrAsp: 2.299 ± 0.372
1.427TyrGlu: 1.427 ± 0.296
1.268TyrPhe: 1.268 ± 0.332
2.458TyrGly: 2.458 ± 0.461
0.793TyrHis: 0.793 ± 0.277
1.744TyrIle: 1.744 ± 0.317
1.348TyrLys: 1.348 ± 0.401
2.061TyrLeu: 2.061 ± 0.419
0.793TyrMet: 0.793 ± 0.242
1.189TyrAsn: 1.189 ± 0.271
1.427TyrPro: 1.427 ± 0.399
1.268TyrGln: 1.268 ± 0.365
2.616TyrArg: 2.616 ± 0.418
2.378TyrSer: 2.378 ± 0.498
1.744TyrThr: 1.744 ± 0.43
2.378TyrVal: 2.378 ± 0.446
0.396TyrTrp: 0.396 ± 0.193
1.903TyrTyr: 1.903 ± 0.42
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 47 proteins (12615 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski