Amino acid dipepetide frequency for Maize yellow dwarf virus-RMV2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.994AlaAla: 3.994 ± 1.361
0.999AlaCys: 0.999 ± 0.887
1.997AlaAsp: 1.997 ± 0.658
5.991AlaGlu: 5.991 ± 0.722
2.496AlaPhe: 2.496 ± 1.011
5.991AlaGly: 5.991 ± 1.84
0.999AlaHis: 0.999 ± 0.444
1.997AlaIle: 1.997 ± 0.646
2.496AlaLys: 2.496 ± 1.594
6.99AlaLeu: 6.99 ± 1.611
1.997AlaMet: 1.997 ± 0.958
2.496AlaAsn: 2.496 ± 1.179
2.996AlaPro: 2.996 ± 0.96
1.997AlaGln: 1.997 ± 0.498
4.993AlaArg: 4.993 ± 1.412
9.985AlaSer: 9.985 ± 2.623
5.492AlaThr: 5.492 ± 1.0
1.498AlaVal: 1.498 ± 0.704
0.499AlaTrp: 0.499 ± 0.403
2.996AlaTyr: 2.996 ± 0.942
0.0AlaXaa: 0.0 ± 0.0
Cys
0.499CysAla: 0.499 ± 0.554
0.499CysCys: 0.499 ± 0.363
0.499CysAsp: 0.499 ± 0.443
1.498CysGlu: 1.498 ± 0.512
0.499CysPhe: 0.499 ± 0.508
0.999CysGly: 0.999 ± 0.887
0.0CysHis: 0.0 ± 0.0
1.498CysIle: 1.498 ± 0.486
0.499CysLys: 0.499 ± 0.363
1.997CysLeu: 1.997 ± 0.985
0.499CysMet: 0.499 ± 0.443
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.999CysArg: 0.999 ± 0.628
1.997CysSer: 1.997 ± 0.926
1.997CysThr: 1.997 ± 0.621
2.496CysVal: 2.496 ± 1.12
0.499CysTrp: 0.499 ± 0.443
0.499CysTyr: 0.499 ± 0.363
0.0CysXaa: 0.0 ± 0.0
Asp
5.492AspAla: 5.492 ± 1.508
0.999AspCys: 0.999 ± 0.493
3.994AspAsp: 3.994 ± 1.174
2.996AspGlu: 2.996 ± 1.1
3.994AspPhe: 3.994 ± 2.885
1.997AspGly: 1.997 ± 0.675
0.499AspHis: 0.499 ± 0.403
2.496AspIle: 2.496 ± 1.302
0.499AspLys: 0.499 ± 0.403
5.492AspLeu: 5.492 ± 0.807
0.499AspMet: 0.499 ± 0.443
0.999AspAsn: 0.999 ± 0.628
2.496AspPro: 2.496 ± 1.052
1.997AspGln: 1.997 ± 1.137
1.997AspArg: 1.997 ± 1.08
4.493AspSer: 4.493 ± 1.779
0.999AspThr: 0.999 ± 0.543
2.996AspVal: 2.996 ± 0.679
0.999AspTrp: 0.999 ± 0.598
0.999AspTyr: 0.999 ± 0.725
0.0AspXaa: 0.0 ± 0.0
Glu
3.994GluAla: 3.994 ± 0.953
1.997GluCys: 1.997 ± 0.998
3.495GluAsp: 3.495 ± 2.285
3.495GluGlu: 3.495 ± 1.306
3.495GluPhe: 3.495 ± 1.75
3.994GluGly: 3.994 ± 1.352
1.997GluHis: 1.997 ± 0.802
3.495GluIle: 3.495 ± 1.066
1.997GluLys: 1.997 ± 0.912
4.493GluLeu: 4.493 ± 1.209
0.499GluMet: 0.499 ± 0.363
0.499GluAsn: 0.499 ± 0.403
2.496GluPro: 2.496 ± 1.594
1.498GluGln: 1.498 ± 0.704
0.999GluArg: 0.999 ± 0.444
4.493GluSer: 4.493 ± 0.824
3.994GluThr: 3.994 ± 0.432
3.994GluVal: 3.994 ± 1.138
1.997GluTrp: 1.997 ± 0.827
1.498GluTyr: 1.498 ± 0.873
0.0GluXaa: 0.0 ± 0.0
Phe
1.498PheAla: 1.498 ± 0.666
1.498PheCys: 1.498 ± 1.017
2.996PheAsp: 2.996 ± 0.97
1.498PheGlu: 1.498 ± 0.864
1.997PhePhe: 1.997 ± 0.97
2.496PheGly: 2.496 ± 0.796
0.999PheHis: 0.999 ± 1.016
1.997PheIle: 1.997 ± 0.766
3.495PheLys: 3.495 ± 1.082
2.996PheLeu: 2.996 ± 1.016
1.997PheMet: 1.997 ± 1.397
0.999PheAsn: 0.999 ± 0.725
0.999PhePro: 0.999 ± 1.016
2.996PheGln: 2.996 ± 0.411
1.997PheArg: 1.997 ± 0.621
1.997PheSer: 1.997 ± 1.818
2.496PheThr: 2.496 ± 1.088
1.498PheVal: 1.498 ± 0.953
0.999PheTrp: 0.999 ± 0.471
0.499PheTyr: 0.499 ± 0.363
0.0PheXaa: 0.0 ± 0.0
Gly
1.498GlyAla: 1.498 ± 0.832
1.997GlyCys: 1.997 ± 1.142
1.997GlyAsp: 1.997 ± 0.863
1.997GlyGlu: 1.997 ± 0.46
4.993GlyPhe: 4.993 ± 1.1
10.984GlyGly: 10.984 ± 2.816
0.999GlyHis: 0.999 ± 0.471
0.499GlyIle: 0.499 ± 0.554
2.496GlyLys: 2.496 ± 1.037
3.994GlyLeu: 3.994 ± 1.565
0.499GlyMet: 0.499 ± 0.403
5.492GlyAsn: 5.492 ± 1.703
2.996GlyPro: 2.996 ± 1.201
0.999GlyGln: 0.999 ± 0.807
6.49GlyArg: 6.49 ± 2.572
8.487GlySer: 8.487 ± 0.554
3.994GlyThr: 3.994 ± 1.459
3.994GlyVal: 3.994 ± 1.219
1.498GlyTrp: 1.498 ± 0.704
3.994GlyTyr: 3.994 ± 1.071
0.0GlyXaa: 0.0 ± 0.0
His
1.498HisAla: 1.498 ± 0.91
0.499HisCys: 0.499 ± 0.443
0.999HisAsp: 0.999 ± 0.543
0.999HisGlu: 0.999 ± 0.641
0.499HisPhe: 0.499 ± 0.363
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.499HisIle: 0.499 ± 0.508
1.498HisLys: 1.498 ± 0.922
2.496HisLeu: 2.496 ± 1.589
0.0HisMet: 0.0 ± 0.0
1.997HisAsn: 1.997 ± 0.621
1.498HisPro: 1.498 ± 0.795
0.999HisGln: 0.999 ± 0.781
0.499HisArg: 0.499 ± 0.363
0.999HisSer: 0.999 ± 0.581
0.999HisThr: 0.999 ± 0.734
1.997HisVal: 1.997 ± 1.06
0.499HisTrp: 0.499 ± 0.363
1.498HisTyr: 1.498 ± 0.666
0.0HisXaa: 0.0 ± 0.0
Ile
2.996IleAla: 2.996 ± 0.828
0.499IleCys: 0.499 ± 0.363
1.997IleAsp: 1.997 ± 0.627
2.996IleGlu: 2.996 ± 1.013
0.499IlePhe: 0.499 ± 0.363
1.498IleGly: 1.498 ± 0.666
0.999IleHis: 0.999 ± 0.853
1.997IleIle: 1.997 ± 0.837
1.997IleLys: 1.997 ± 0.667
3.495IleLeu: 3.495 ± 1.093
0.499IleMet: 0.499 ± 0.443
1.498IleAsn: 1.498 ± 0.823
3.495IlePro: 3.495 ± 1.066
0.0IleGln: 0.0 ± 0.0
3.495IleArg: 3.495 ± 2.125
6.49IleSer: 6.49 ± 1.437
2.996IleThr: 2.996 ± 0.826
1.498IleVal: 1.498 ± 0.795
0.0IleTrp: 0.0 ± 0.0
0.999IleTyr: 0.999 ± 0.493
0.0IleXaa: 0.0 ± 0.0
Lys
2.996LysAla: 2.996 ± 0.757
0.499LysCys: 0.499 ± 0.443
2.996LysAsp: 2.996 ± 0.668
0.999LysGlu: 0.999 ± 0.543
1.997LysPhe: 1.997 ± 0.735
4.493LysGly: 4.493 ± 1.205
0.499LysHis: 0.499 ± 0.363
3.994LysIle: 3.994 ± 1.391
0.999LysLys: 0.999 ± 0.725
3.994LysLeu: 3.994 ± 0.966
1.498LysMet: 1.498 ± 0.906
1.498LysAsn: 1.498 ± 0.704
1.997LysPro: 1.997 ± 1.06
1.997LysGln: 1.997 ± 1.086
1.498LysArg: 1.498 ± 0.494
3.994LysSer: 3.994 ± 1.419
3.495LysThr: 3.495 ± 1.551
5.492LysVal: 5.492 ± 1.882
0.499LysTrp: 0.499 ± 0.443
0.499LysTyr: 0.499 ± 0.363
0.0LysXaa: 0.0 ± 0.0
Leu
6.99LeuAla: 6.99 ± 1.013
1.997LeuCys: 1.997 ± 0.985
3.495LeuAsp: 3.495 ± 1.662
6.99LeuGlu: 6.99 ± 0.841
3.994LeuPhe: 3.994 ± 1.565
4.993LeuGly: 4.993 ± 1.648
3.994LeuHis: 3.994 ± 1.984
2.996LeuIle: 2.996 ± 1.245
2.996LeuLys: 2.996 ± 0.668
10.484LeuLeu: 10.484 ± 2.892
1.997LeuMet: 1.997 ± 0.979
2.496LeuAsn: 2.496 ± 0.887
3.495LeuPro: 3.495 ± 1.236
6.49LeuGln: 6.49 ± 1.177
6.49LeuArg: 6.49 ± 1.781
9.985LeuSer: 9.985 ± 1.074
5.991LeuThr: 5.991 ± 1.306
6.49LeuVal: 6.49 ± 2.258
0.499LeuTrp: 0.499 ± 0.443
1.997LeuTyr: 1.997 ± 1.157
0.0LeuXaa: 0.0 ± 0.0
Met
1.997MetAla: 1.997 ± 0.827
0.0MetCys: 0.0 ± 0.0
0.499MetAsp: 0.499 ± 0.6
0.499MetGlu: 0.499 ± 0.443
0.499MetPhe: 0.499 ± 0.6
1.498MetGly: 1.498 ± 0.656
0.0MetHis: 0.0 ± 0.0
0.999MetIle: 0.999 ± 0.493
0.499MetLys: 0.499 ± 0.363
1.498MetLeu: 1.498 ± 0.486
0.0MetMet: 0.0 ± 0.0
1.498MetAsn: 1.498 ± 0.823
0.499MetPro: 0.499 ± 0.6
0.499MetGln: 0.499 ± 0.363
0.999MetArg: 0.999 ± 0.471
2.496MetSer: 2.496 ± 1.427
0.999MetThr: 0.999 ± 0.543
0.999MetVal: 0.999 ± 0.444
0.0MetTrp: 0.0 ± 0.0
1.498MetTyr: 1.498 ± 0.512
0.0MetXaa: 0.0 ± 0.0
Asn
3.994AsnAla: 3.994 ± 0.953
0.0AsnCys: 0.0 ± 0.0
1.997AsnAsp: 1.997 ± 0.888
0.499AsnGlu: 0.499 ± 0.403
0.999AsnPhe: 0.999 ± 0.628
3.994AsnGly: 3.994 ± 1.019
0.0AsnHis: 0.0 ± 0.0
0.499AsnIle: 0.499 ± 0.508
4.993AsnLys: 4.993 ± 1.177
2.996AsnLeu: 2.996 ± 0.681
0.499AsnMet: 0.499 ± 0.333
3.495AsnAsn: 3.495 ± 0.941
2.996AsnPro: 2.996 ± 1.239
1.997AsnGln: 1.997 ± 0.869
3.994AsnArg: 3.994 ± 1.019
4.993AsnSer: 4.993 ± 1.219
2.996AsnThr: 2.996 ± 1.173
0.499AsnVal: 0.499 ± 0.554
0.499AsnTrp: 0.499 ± 0.363
1.498AsnTyr: 1.498 ± 1.21
0.0AsnXaa: 0.0 ± 0.0
Pro
2.996ProAla: 2.996 ± 0.985
0.0ProCys: 0.0 ± 0.0
1.498ProAsp: 1.498 ± 0.767
2.496ProGlu: 2.496 ± 0.966
0.999ProPhe: 0.999 ± 0.471
2.996ProGly: 2.996 ± 1.312
1.498ProHis: 1.498 ± 0.587
1.997ProIle: 1.997 ± 0.564
2.996ProLys: 2.996 ± 1.196
2.496ProLeu: 2.496 ± 1.122
0.0ProMet: 0.0 ± 0.0
1.498ProAsn: 1.498 ± 0.767
6.99ProPro: 6.99 ± 2.602
3.495ProGln: 3.495 ± 1.223
4.993ProArg: 4.993 ± 2.298
7.489ProSer: 7.489 ± 3.169
5.492ProThr: 5.492 ± 0.883
3.994ProVal: 3.994 ± 1.193
0.499ProTrp: 0.499 ± 0.403
1.997ProTyr: 1.997 ± 0.918
0.0ProXaa: 0.0 ± 0.0
Gln
4.993GlnAla: 4.993 ± 2.672
1.498GlnCys: 1.498 ± 0.642
1.498GlnAsp: 1.498 ± 0.486
1.498GlnGlu: 1.498 ± 0.656
0.999GlnPhe: 0.999 ± 0.444
2.496GlnGly: 2.496 ± 1.371
1.498GlnHis: 1.498 ± 0.761
1.997GlnIle: 1.997 ± 0.837
3.495GlnLys: 3.495 ± 1.384
3.495GlnLeu: 3.495 ± 1.079
0.0GlnMet: 0.0 ± 0.0
4.493GlnAsn: 4.493 ± 1.5
0.999GlnPro: 0.999 ± 0.57
2.996GlnGln: 2.996 ± 0.988
3.495GlnArg: 3.495 ± 0.991
2.496GlnSer: 2.496 ± 1.723
2.996GlnThr: 2.996 ± 1.528
1.498GlnVal: 1.498 ± 0.884
0.499GlnTrp: 0.499 ± 0.6
0.499GlnTyr: 0.499 ± 0.403
0.0GlnXaa: 0.0 ± 0.0
Arg
4.993ArgAla: 4.993 ± 1.506
0.999ArgCys: 0.999 ± 1.016
3.495ArgAsp: 3.495 ± 2.185
4.493ArgGlu: 4.493 ± 0.776
1.997ArgPhe: 1.997 ± 1.397
3.994ArgGly: 3.994 ± 1.388
1.498ArgHis: 1.498 ± 1.017
2.496ArgIle: 2.496 ± 0.492
0.999ArgLys: 0.999 ± 0.444
10.984ArgLeu: 10.984 ± 2.428
1.997ArgMet: 1.997 ± 0.571
3.994ArgAsn: 3.994 ± 1.431
5.492ArgPro: 5.492 ± 2.005
1.498ArgGln: 1.498 ± 0.656
9.486ArgArg: 9.486 ± 5.419
3.495ArgSer: 3.495 ± 1.642
1.997ArgThr: 1.997 ± 0.588
4.493ArgVal: 4.493 ± 1.821
0.499ArgTrp: 0.499 ± 0.363
1.498ArgTyr: 1.498 ± 0.864
0.0ArgXaa: 0.0 ± 0.0
Ser
4.993SerAla: 4.993 ± 1.77
1.997SerCys: 1.997 ± 1.451
4.493SerAsp: 4.493 ± 0.636
3.994SerGlu: 3.994 ± 1.804
2.496SerPhe: 2.496 ± 0.808
5.492SerGly: 5.492 ± 1.635
0.999SerHis: 0.999 ± 0.734
5.991SerIle: 5.991 ± 1.509
4.993SerLys: 4.993 ± 0.915
11.483SerLeu: 11.483 ± 1.684
0.999SerMet: 0.999 ± 0.869
4.493SerAsn: 4.493 ± 1.139
7.489SerPro: 7.489 ± 1.892
4.493SerGln: 4.493 ± 1.817
6.99SerArg: 6.99 ± 3.207
10.484SerSer: 10.484 ± 1.844
3.994SerThr: 3.994 ± 1.272
8.987SerVal: 8.987 ± 1.395
1.997SerTrp: 1.997 ± 0.888
3.495SerTyr: 3.495 ± 0.568
0.0SerXaa: 0.0 ± 0.0
Thr
2.996ThrAla: 2.996 ± 1.186
1.498ThrCys: 1.498 ± 0.486
3.994ThrAsp: 3.994 ± 1.757
3.495ThrGlu: 3.495 ± 0.787
1.997ThrPhe: 1.997 ± 1.03
5.492ThrGly: 5.492 ± 1.414
0.499ThrHis: 0.499 ± 0.6
1.997ThrIle: 1.997 ± 1.762
2.496ThrLys: 2.496 ± 0.782
5.991ThrLeu: 5.991 ± 1.211
0.999ThrMet: 0.999 ± 0.581
1.997ThrAsn: 1.997 ± 0.658
5.492ThrPro: 5.492 ± 2.428
0.999ThrGln: 0.999 ± 0.725
4.993ThrArg: 4.993 ± 1.562
5.991ThrSer: 5.991 ± 2.405
3.994ThrThr: 3.994 ± 1.624
2.996ThrVal: 2.996 ± 1.309
0.999ThrTrp: 0.999 ± 0.493
1.997ThrTyr: 1.997 ± 0.888
0.0ThrXaa: 0.0 ± 0.0
Val
7.489ValAla: 7.489 ± 1.274
0.0ValCys: 0.0 ± 0.0
1.498ValAsp: 1.498 ± 0.743
4.493ValGlu: 4.493 ± 1.535
1.997ValPhe: 1.997 ± 1.03
3.994ValGly: 3.994 ± 1.001
0.999ValHis: 0.999 ± 0.725
0.999ValIle: 0.999 ± 0.444
2.496ValLys: 2.496 ± 0.771
5.991ValLeu: 5.991 ± 1.836
0.999ValMet: 0.999 ± 0.847
2.496ValAsn: 2.496 ± 0.492
2.996ValPro: 2.996 ± 1.032
5.991ValGln: 5.991 ± 1.299
2.996ValArg: 2.996 ± 0.842
6.49ValSer: 6.49 ± 2.185
3.495ValThr: 3.495 ± 0.868
6.49ValVal: 6.49 ± 1.777
0.999ValTrp: 0.999 ± 0.769
1.997ValTyr: 1.997 ± 0.926
0.0ValXaa: 0.0 ± 0.0
Trp
1.997TrpAla: 1.997 ± 0.755
0.0TrpCys: 0.0 ± 0.0
0.999TrpAsp: 0.999 ± 0.628
0.499TrpGlu: 0.499 ± 0.363
0.0TrpPhe: 0.0 ± 0.0
0.499TrpGly: 0.499 ± 0.403
0.499TrpHis: 0.499 ± 0.403
0.499TrpIle: 0.499 ± 0.363
0.499TrpLys: 0.499 ± 0.363
1.997TrpLeu: 1.997 ± 1.015
0.999TrpMet: 0.999 ± 0.493
0.499TrpAsn: 0.499 ± 0.363
0.499TrpPro: 0.499 ± 0.363
1.498TrpGln: 1.498 ± 0.494
1.498TrpArg: 1.498 ± 0.774
2.496TrpSer: 2.496 ± 0.527
0.0TrpThr: 0.0 ± 0.0
0.499TrpVal: 0.499 ± 0.363
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.999TyrAla: 0.999 ± 0.725
0.0TyrCys: 0.0 ± 0.0
2.496TyrAsp: 2.496 ± 1.088
2.996TyrGlu: 2.996 ± 1.013
1.498TyrPhe: 1.498 ± 0.537
1.997TyrGly: 1.997 ± 0.46
1.498TyrHis: 1.498 ± 0.774
0.999TyrIle: 0.999 ± 0.444
3.495TyrLys: 3.495 ± 1.33
1.498TyrLeu: 1.498 ± 0.486
0.499TyrMet: 0.499 ± 0.403
0.999TyrAsn: 0.999 ± 0.887
0.499TyrPro: 0.499 ± 0.363
0.999TyrGln: 0.999 ± 0.581
1.498TyrArg: 1.498 ± 0.656
1.498TyrSer: 1.498 ± 0.704
2.496TyrThr: 2.496 ± 0.898
2.496TyrVal: 2.496 ± 1.371
1.498TyrTrp: 1.498 ± 0.884
0.999TyrTyr: 0.999 ± 0.807
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2004 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski