Amino acid dipepetide frequency for Alkalicaulis satelles

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.606AlaAla: 22.606 ± 0.249	1.474AlaCys: 1.474 ± 0.047	8.17AlaAsp: 8.17 ± 0.106	8.492AlaGlu: 8.492 ± 0.12	5.264AlaPhe: 5.264 ± 0.09	14.278AlaGly: 14.278 ± 0.166	2.807AlaHis: 2.807 ± 0.068	5.668AlaIle: 5.668 ± 0.078	2.763AlaLys: 2.763 ± 0.08	17.821AlaLeu: 17.821 ± 0.205	3.769AlaMet: 3.769 ± 0.07	2.529AlaAsn: 2.529 ± 0.054	8.43AlaPro: 8.43 ± 0.131	4.528AlaGln: 4.528 ± 0.076	14.004AlaArg: 14.004 ± 0.174	7.262AlaSer: 7.262 ± 0.097	3.884AlaThr: 3.884 ± 0.066	9.483AlaVal: 9.483 ± 0.119	1.986AlaTrp: 1.986 ± 0.054	2.776AlaTyr: 2.776 ± 0.062	0.0AlaXaa: 0.0 ± 0.0
Cys	1.324CysAla: 1.324 ± 0.043	0.068CysCys: 0.068 ± 0.01	0.518CysAsp: 0.518 ± 0.023	0.507CysGlu: 0.507 ± 0.027	0.252CysPhe: 0.252 ± 0.019	0.822CysGly: 0.822 ± 0.032	0.164CysHis: 0.164 ± 0.014	0.269CysIle: 0.269 ± 0.019	0.146CysLys: 0.146 ± 0.013	0.729CysLeu: 0.729 ± 0.029	0.117CysMet: 0.117 ± 0.012	0.179CysAsn: 0.179 ± 0.014	0.448CysPro: 0.448 ± 0.023	0.234CysGln: 0.234 ± 0.017	0.529CysArg: 0.529 ± 0.026	0.353CysSer: 0.353 ± 0.022	0.345CysThr: 0.345 ± 0.021	0.617CysVal: 0.617 ± 0.026	0.097CysTrp: 0.097 ± 0.012	0.131CysTyr: 0.131 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.946AspAla: 8.946 ± 0.117	0.418AspCys: 0.418 ± 0.024	3.176AspAsp: 3.176 ± 0.073	3.813AspGlu: 3.813 ± 0.076	2.204AspPhe: 2.204 ± 0.055	5.865AspGly: 5.865 ± 0.09	1.278AspHis: 1.278 ± 0.04	2.793AspIle: 2.793 ± 0.05	1.253AspLys: 1.253 ± 0.044	5.996AspLeu: 5.996 ± 0.095	1.52AspMet: 1.52 ± 0.04	1.163AspAsn: 1.163 ± 0.039	4.165AspPro: 4.165 ± 0.073	1.74AspGln: 1.74 ± 0.04	4.254AspArg: 4.254 ± 0.082	2.299AspSer: 2.299 ± 0.049	2.408AspThr: 2.408 ± 0.053	4.127AspVal: 4.127 ± 0.071	1.137AspTrp: 1.137 ± 0.039	1.478AspTyr: 1.478 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	10.989GluAla: 10.989 ± 0.141	0.299GluCys: 0.299 ± 0.02	3.687GluAsp: 3.687 ± 0.073	3.136GluGlu: 3.136 ± 0.066	1.638GluPhe: 1.638 ± 0.048	5.23GluGly: 5.23 ± 0.082	1.163GluHis: 1.163 ± 0.039	3.189GluIle: 3.189 ± 0.067	1.303GluLys: 1.303 ± 0.041	5.26GluLeu: 5.26 ± 0.08	1.394GluMet: 1.394 ± 0.045	1.247GluAsn: 1.247 ± 0.041	3.267GluPro: 3.267 ± 0.08	1.865GluGln: 1.865 ± 0.044	5.962GluArg: 5.962 ± 0.103	2.394GluSer: 2.394 ± 0.056	4.157GluThr: 4.157 ± 0.072	3.321GluVal: 3.321 ± 0.075	0.633GluTrp: 0.633 ± 0.028	0.965GluTyr: 0.965 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	5.141PheAla: 5.141 ± 0.086	0.312PheCys: 0.312 ± 0.019	2.818PheAsp: 2.818 ± 0.067	2.651PheGlu: 2.651 ± 0.054	1.39PhePhe: 1.39 ± 0.045	3.27PheGly: 3.27 ± 0.072	0.727PheHis: 0.727 ± 0.031	1.716PheIle: 1.716 ± 0.048	0.798PheLys: 0.798 ± 0.034	3.092PheLeu: 3.092 ± 0.065	0.818PheMet: 0.818 ± 0.028	1.086PheAsn: 1.086 ± 0.043	1.449PhePro: 1.449 ± 0.038	0.941PheGln: 0.941 ± 0.033	2.074PheArg: 2.074 ± 0.047	2.079PheSer: 2.079 ± 0.049	2.077PheThr: 2.077 ± 0.045	2.365PheVal: 2.365 ± 0.053	0.529PheTrp: 0.529 ± 0.029	0.822PheTyr: 0.822 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	13.577GlyAla: 13.577 ± 0.179	0.737GlyCys: 0.737 ± 0.03	4.651GlyAsp: 4.651 ± 0.08	6.213GlyGlu: 6.213 ± 0.091	3.782GlyPhe: 3.782 ± 0.078	8.023GlyGly: 8.023 ± 0.109	1.788GlyHis: 1.788 ± 0.052	2.799GlyIle: 2.799 ± 0.076	2.216GlyLys: 2.216 ± 0.056	9.644GlyLeu: 9.644 ± 0.123	2.132GlyMet: 2.132 ± 0.052	1.392GlyAsn: 1.392 ± 0.052	4.487GlyPro: 4.487 ± 0.085	3.06GlyGln: 3.06 ± 0.066	7.002GlyArg: 7.002 ± 0.099	3.981GlySer: 3.981 ± 0.068	2.93GlyThr: 2.93 ± 0.056	7.343GlyVal: 7.343 ± 0.092	1.637GlyTrp: 1.637 ± 0.049	2.098GlyTyr: 2.098 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.775HisAla: 2.775 ± 0.069	0.199HisCys: 0.199 ± 0.014	1.292HisAsp: 1.292 ± 0.041	1.193HisGlu: 1.193 ± 0.041	0.762HisPhe: 0.762 ± 0.032	1.924HisGly: 1.924 ± 0.049	0.535HisHis: 0.535 ± 0.028	0.847HisIle: 0.847 ± 0.034	0.433HisLys: 0.433 ± 0.021	1.851HisLeu: 1.851 ± 0.052	0.431HisMet: 0.431 ± 0.023	0.43HisAsn: 0.43 ± 0.023	1.318HisPro: 1.318 ± 0.037	0.584HisGln: 0.584 ± 0.027	1.222HisArg: 1.222 ± 0.039	0.764HisSer: 0.764 ± 0.033	0.779HisThr: 0.779 ± 0.031	1.52HisVal: 1.52 ± 0.049	0.304HisTrp: 0.304 ± 0.02	0.516HisTyr: 0.516 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.51IleAla: 7.51 ± 0.105	0.407IleCys: 0.407 ± 0.022	3.074IleAsp: 3.074 ± 0.058	3.458IleGlu: 3.458 ± 0.067	1.359IlePhe: 1.359 ± 0.043	4.0IleGly: 4.0 ± 0.079	0.9IleHis: 0.9 ± 0.033	2.025IleIle: 2.025 ± 0.056	1.057IleLys: 1.057 ± 0.043	3.917IleLeu: 3.917 ± 0.078	0.851IleMet: 0.851 ± 0.032	1.254IleAsn: 1.254 ± 0.041	1.91IlePro: 1.91 ± 0.046	1.057IleGln: 1.057 ± 0.038	2.973IleArg: 2.973 ± 0.058	2.459IleSer: 2.459 ± 0.054	2.694IleThr: 2.694 ± 0.064	3.15IleVal: 3.15 ± 0.066	0.567IleTrp: 0.567 ± 0.027	0.915IleTyr: 0.915 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.679LysAla: 3.679 ± 0.089	0.093LysCys: 0.093 ± 0.011	1.352LysAsp: 1.352 ± 0.043	1.046LysGlu: 1.046 ± 0.038	0.615LysPhe: 0.615 ± 0.029	1.993LysGly: 1.993 ± 0.058	0.389LysHis: 0.389 ± 0.022	1.074LysIle: 1.074 ± 0.039	0.872LysLys: 0.872 ± 0.047	2.246LysLeu: 2.246 ± 0.066	0.489LysMet: 0.489 ± 0.025	0.509LysAsn: 0.509 ± 0.027	1.576LysPro: 1.576 ± 0.048	0.57LysGln: 0.57 ± 0.03	1.979LysArg: 1.979 ± 0.052	1.313LysSer: 1.313 ± 0.046	1.529LysThr: 1.529 ± 0.047	1.445LysVal: 1.445 ± 0.046	0.21LysTrp: 0.21 ± 0.016	0.377LysTyr: 0.377 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	15.533LeuAla: 15.533 ± 0.206	0.76LeuCys: 0.76 ± 0.028	6.834LeuAsp: 6.834 ± 0.102	6.253LeuGlu: 6.253 ± 0.089	3.417LeuPhe: 3.417 ± 0.069	7.981LeuGly: 7.981 ± 0.124	1.908LeuHis: 1.908 ± 0.05	5.79LeuIle: 5.79 ± 0.087	3.233LeuLys: 3.233 ± 0.085	7.689LeuLeu: 7.689 ± 0.124	2.65LeuMet: 2.65 ± 0.063	2.481LeuAsn: 2.481 ± 0.055	4.981LeuPro: 4.981 ± 0.081	2.517LeuGln: 2.517 ± 0.056	6.929LeuArg: 6.929 ± 0.105	6.289LeuSer: 6.289 ± 0.084	5.9LeuThr: 5.9 ± 0.091	6.343LeuVal: 6.343 ± 0.099	1.164LeuTrp: 1.164 ± 0.044	2.036LeuTyr: 2.036 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	3.678MetAla: 3.678 ± 0.069	0.14MetCys: 0.14 ± 0.013	1.316MetAsp: 1.316 ± 0.035	1.262MetGlu: 1.262 ± 0.037	0.595MetPhe: 0.595 ± 0.025	1.886MetGly: 1.886 ± 0.048	0.401MetHis: 0.401 ± 0.024	1.348MetIle: 1.348 ± 0.041	0.823MetLys: 0.823 ± 0.034	2.108MetLeu: 2.108 ± 0.055	0.58MetMet: 0.58 ± 0.028	0.665MetAsn: 0.665 ± 0.026	1.102MetPro: 1.102 ± 0.039	0.648MetGln: 0.648 ± 0.028	1.957MetArg: 1.957 ± 0.049	1.674MetSer: 1.674 ± 0.048	1.892MetThr: 1.892 ± 0.048	1.392MetVal: 1.392 ± 0.04	0.196MetTrp: 0.196 ± 0.014	0.252MetTyr: 0.252 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.155AsnAla: 3.155 ± 0.062	0.171AsnCys: 0.171 ± 0.014	1.108AsnAsp: 1.108 ± 0.038	1.059AsnGlu: 1.059 ± 0.04	0.839AsnPhe: 0.839 ± 0.038	1.769AsnGly: 1.769 ± 0.05	0.41AsnHis: 0.41 ± 0.021	1.059AsnIle: 1.059 ± 0.041	0.453AsnLys: 0.453 ± 0.022	2.215AsnLeu: 2.215 ± 0.053	0.503AsnMet: 0.503 ± 0.023	0.605AsnAsn: 0.605 ± 0.032	1.653AsnPro: 1.653 ± 0.049	0.628AsnGln: 0.628 ± 0.028	1.603AsnArg: 1.603 ± 0.044	0.865AsnSer: 0.865 ± 0.039	1.138AsnThr: 1.138 ± 0.041	1.474AsnVal: 1.474 ± 0.049	0.331AsnTrp: 0.331 ± 0.019	0.533AsnTyr: 0.533 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	7.673ProAla: 7.673 ± 0.115	0.378ProCys: 0.378 ± 0.023	4.702ProAsp: 4.702 ± 0.091	4.157ProGlu: 4.157 ± 0.078	1.943ProPhe: 1.943 ± 0.049	6.046ProGly: 6.046 ± 0.097	1.061ProHis: 1.061 ± 0.037	1.616ProIle: 1.616 ± 0.049	1.07ProLys: 1.07 ± 0.035	4.522ProLeu: 4.522 ± 0.079	1.11ProMet: 1.11 ± 0.038	1.059ProAsn: 1.059 ± 0.044	2.648ProPro: 2.648 ± 0.079	1.541ProGln: 1.541 ± 0.043	3.39ProArg: 3.39 ± 0.063	2.676ProSer: 2.676 ± 0.059	1.497ProThr: 1.497 ± 0.044	4.668ProVal: 4.668 ± 0.073	0.782ProTrp: 0.782 ± 0.031	1.066ProTyr: 1.066 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	4.741GlnAla: 4.741 ± 0.087	0.199GlnCys: 0.199 ± 0.016	1.577GlnAsp: 1.577 ± 0.046	1.358GlnGlu: 1.358 ± 0.043	0.958GlnPhe: 0.958 ± 0.037	2.561GlnGly: 2.561 ± 0.057	0.484GlnHis: 0.484 ± 0.024	1.54GlnIle: 1.54 ± 0.044	0.566GlnLys: 0.566 ± 0.03	2.685GlnLeu: 2.685 ± 0.064	0.754GlnMet: 0.754 ± 0.03	0.614GlnAsn: 0.614 ± 0.028	1.537GlnPro: 1.537 ± 0.048	0.777GlnGln: 0.777 ± 0.035	2.569GlnArg: 2.569 ± 0.058	1.679GlnSer: 1.679 ± 0.049	1.734GlnThr: 1.734 ± 0.048	2.042GlnVal: 2.042 ± 0.052	0.378GlnTrp: 0.378 ± 0.021	0.523GlnTyr: 0.523 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	11.806ArgAla: 11.806 ± 0.155	0.52ArgCys: 0.52 ± 0.024	4.372ArgAsp: 4.372 ± 0.08	4.969ArgGlu: 4.969 ± 0.094	3.408ArgPhe: 3.408 ± 0.059	5.332ArgGly: 5.332 ± 0.083	1.693ArgHis: 1.693 ± 0.056	3.86ArgIle: 3.86 ± 0.068	1.957ArgLys: 1.957 ± 0.053	9.455ArgLeu: 9.455 ± 0.12	1.932ArgMet: 1.932 ± 0.054	1.587ArgAsn: 1.587 ± 0.046	4.223ArgPro: 4.223 ± 0.085	2.684ArgGln: 2.684 ± 0.063	6.386ArgArg: 6.386 ± 0.109	3.592ArgSer: 3.592 ± 0.071	3.833ArgThr: 3.833 ± 0.064	5.171ArgVal: 5.171 ± 0.08	1.24ArgTrp: 1.24 ± 0.04	1.805ArgTyr: 1.805 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	7.285SerAla: 7.285 ± 0.099	0.33SerCys: 0.33 ± 0.023	3.082SerAsp: 3.082 ± 0.066	2.979SerGlu: 2.979 ± 0.069	1.811SerPhe: 1.811 ± 0.048	5.68SerGly: 5.68 ± 0.09	0.952SerHis: 0.952 ± 0.032	2.04SerIle: 2.04 ± 0.051	1.066SerLys: 1.066 ± 0.041	4.875SerLeu: 4.875 ± 0.087	1.225SerMet: 1.225 ± 0.04	1.03SerAsn: 1.03 ± 0.037	2.746SerPro: 2.746 ± 0.05	1.607SerGln: 1.607 ± 0.049	3.656SerArg: 3.656 ± 0.072	2.269SerSer: 2.269 ± 0.055	1.963SerThr: 1.963 ± 0.05	3.758SerVal: 3.758 ± 0.075	0.84SerTrp: 0.84 ± 0.033	0.994SerTyr: 0.994 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	6.213ThrAla: 6.213 ± 0.089	0.352ThrCys: 0.352 ± 0.024	2.446ThrAsp: 2.446 ± 0.058	2.243ThrGlu: 2.243 ± 0.049	1.465ThrPhe: 1.465 ± 0.048	5.648ThrGly: 5.648 ± 0.091	0.934ThrHis: 0.934 ± 0.034	1.965ThrIle: 1.965 ± 0.052	0.792ThrLys: 0.792 ± 0.029	5.596ThrLeu: 5.596 ± 0.077	0.787ThrMet: 0.787 ± 0.028	0.999ThrAsn: 0.999 ± 0.037	3.342ThrPro: 3.342 ± 0.063	1.256ThrGln: 1.256 ± 0.038	3.855ThrArg: 3.855 ± 0.071	2.048ThrSer: 2.048 ± 0.047	1.89ThrThr: 1.89 ± 0.051	3.436ThrVal: 3.436 ± 0.068	0.533ThrTrp: 0.533 ± 0.026	0.92ThrTyr: 0.92 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	6.999ValAla: 6.999 ± 0.096	0.658ValCys: 0.658 ± 0.029	3.742ValAsp: 3.742 ± 0.074	4.385ValGlu: 4.385 ± 0.082	3.102ValPhe: 3.102 ± 0.056	4.192ValGly: 4.192 ± 0.083	1.4ValHis: 1.4 ± 0.041	4.41ValIle: 4.41 ± 0.074	1.791ValLys: 1.791 ± 0.046	7.23ValLeu: 7.23 ± 0.106	2.062ValMet: 2.062 ± 0.05	1.885ValAsn: 1.885 ± 0.058	2.637ValPro: 2.637 ± 0.052	1.941ValGln: 1.941 ± 0.054	6.106ValArg: 6.106 ± 0.096	4.404ValSer: 4.404 ± 0.082	4.278ValThr: 4.278 ± 0.083	4.499ValVal: 4.499 ± 0.082	1.169ValTrp: 1.169 ± 0.043	1.477ValTyr: 1.477 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.539TrpAla: 1.539 ± 0.044	0.125TrpCys: 0.125 ± 0.013	0.703TrpAsp: 0.703 ± 0.033	0.613TrpGlu: 0.613 ± 0.031	0.558TrpPhe: 0.558 ± 0.025	0.945TrpGly: 0.945 ± 0.035	0.259TrpHis: 0.259 ± 0.016	0.697TrpIle: 0.697 ± 0.029	0.29TrpLys: 0.29 ± 0.019	1.78TrpLeu: 1.78 ± 0.054	0.397TrpMet: 0.397 ± 0.02	0.368TrpAsn: 0.368 ± 0.022	0.754TrpPro: 0.754 ± 0.03	0.379TrpGln: 0.379 ± 0.021	1.826TrpArg: 1.826 ± 0.045	0.865TrpSer: 0.865 ± 0.032	0.928TrpThr: 0.928 ± 0.035	0.803TrpVal: 0.803 ± 0.031	0.198TrpTrp: 0.198 ± 0.016	0.24TrpTyr: 0.24 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.828TyrAla: 2.828 ± 0.061	0.207TyrCys: 0.207 ± 0.016	1.414TyrAsp: 1.414 ± 0.043	1.314TyrGlu: 1.314 ± 0.04	0.792TyrPhe: 0.792 ± 0.025	2.043TyrGly: 2.043 ± 0.051	0.426TyrHis: 0.426 ± 0.021	0.832TyrIle: 0.832 ± 0.026	0.474TyrLys: 0.474 ± 0.025	1.977TyrLeu: 1.977 ± 0.054	0.392TyrMet: 0.392 ± 0.025	0.488TyrAsn: 0.488 ± 0.025	0.933TyrPro: 0.933 ± 0.03	0.722TyrGln: 0.722 ± 0.03	1.549TyrArg: 1.549 ± 0.047	0.919TyrSer: 0.919 ± 0.036	0.863TyrThr: 0.863 ± 0.035	1.411TyrVal: 1.411 ± 0.037	0.336TyrTrp: 0.336 ± 0.02	0.468TyrTyr: 0.468 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2694 proteins (872582 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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