Amino acid dipepetide frequency for Fusarium graminearum hypovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.928AlaAla: 5.928 ± 0.098
1.546AlaCys: 1.546 ± 1.774
4.124AlaAsp: 4.124 ± 1.762
5.155AlaGlu: 5.155 ± 2.202
3.866AlaPhe: 3.866 ± 3.217
4.381AlaGly: 4.381 ± 1.872
2.32AlaHis: 2.32 ± 0.991
4.381AlaIle: 4.381 ± 1.872
4.124AlaLys: 4.124 ± 3.107
6.443AlaLeu: 6.443 ± 2.116
1.546AlaMet: 1.546 ± 0.661
3.608AlaAsn: 3.608 ± 1.541
3.608AlaPro: 3.608 ± 3.327
2.835AlaGln: 2.835 ± 1.211
5.928AlaArg: 5.928 ± 2.532
2.577AlaSer: 2.577 ± 1.101
5.155AlaThr: 5.155 ± 2.202
3.093AlaVal: 3.093 ± 3.547
2.062AlaTrp: 2.062 ± 1.553
2.835AlaTyr: 2.835 ± 1.211
0.0AlaXaa: 0.0 ± 0.0
Cys
1.546CysAla: 1.546 ± 0.661
0.0CysCys: 0.0 ± 0.0
0.515CysAsp: 0.515 ± 0.22
1.289CysGlu: 1.289 ± 1.884
0.258CysPhe: 0.258 ± 0.11
0.773CysGly: 0.773 ± 2.104
0.0CysHis: 0.0 ± 0.0
0.773CysIle: 0.773 ± 2.104
1.031CysLys: 1.031 ± 0.44
1.031CysLeu: 1.031 ± 0.44
0.0CysMet: 0.0 ± 0.0
0.515CysAsn: 0.515 ± 0.22
1.031CysPro: 1.031 ± 0.44
0.515CysGln: 0.515 ± 0.22
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.258CysThr: 0.258 ± 0.11
0.773CysVal: 0.773 ± 0.33
1.289CysTrp: 1.289 ± 1.884
0.258CysTyr: 0.258 ± 0.11
0.0CysXaa: 0.0 ± 0.0
Asp
4.381AspAla: 4.381 ± 2.997
0.515AspCys: 0.515 ± 0.22
6.186AspAsp: 6.186 ± 0.208
3.093AspGlu: 3.093 ± 1.113
2.32AspPhe: 2.32 ± 1.443
3.351AspGly: 3.351 ± 1.003
1.289AspHis: 1.289 ± 0.551
2.835AspIle: 2.835 ± 1.211
2.062AspLys: 2.062 ± 0.881
4.124AspLeu: 4.124 ± 0.673
1.289AspMet: 1.289 ± 0.551
2.062AspAsn: 2.062 ± 0.881
3.608AspPro: 3.608 ± 0.893
1.289AspGln: 1.289 ± 0.551
1.804AspArg: 1.804 ± 0.771
2.577AspSer: 2.577 ± 1.101
3.866AspThr: 3.866 ± 0.783
4.897AspVal: 4.897 ± 0.342
1.031AspTrp: 1.031 ± 0.44
2.577AspTyr: 2.577 ± 1.333
0.0AspXaa: 0.0 ± 0.0
Glu
4.639GluAla: 4.639 ± 0.452
0.515GluCys: 0.515 ± 2.214
2.577GluAsp: 2.577 ± 1.101
3.608GluGlu: 3.608 ± 1.541
2.32GluPhe: 2.32 ± 0.991
4.639GluGly: 4.639 ± 2.887
1.546GluHis: 1.546 ± 0.661
5.155GluIle: 5.155 ± 0.232
3.351GluLys: 3.351 ± 1.431
3.351GluLeu: 3.351 ± 1.003
1.804GluMet: 1.804 ± 0.771
1.804GluAsn: 1.804 ± 0.771
2.835GluPro: 2.835 ± 1.211
2.577GluGln: 2.577 ± 1.101
5.155GluArg: 5.155 ± 2.666
2.577GluSer: 2.577 ± 1.101
2.835GluThr: 2.835 ± 3.657
3.866GluVal: 3.866 ± 1.652
1.289GluTrp: 1.289 ± 1.884
1.289GluTyr: 1.289 ± 1.884
0.0GluXaa: 0.0 ± 0.0
Phe
4.124PheAla: 4.124 ± 1.762
0.515PheCys: 0.515 ± 0.22
2.062PheAsp: 2.062 ± 3.988
1.804PheGlu: 1.804 ± 1.664
2.577PhePhe: 2.577 ± 1.101
3.608PheGly: 3.608 ± 0.893
1.289PheHis: 1.289 ± 0.551
3.608PheIle: 3.608 ± 1.541
3.608PheLys: 3.608 ± 1.541
3.608PheLeu: 3.608 ± 3.327
0.515PheMet: 0.515 ± 0.22
1.289PheAsn: 1.289 ± 0.551
2.32PhePro: 2.32 ± 0.991
2.062PheGln: 2.062 ± 0.881
2.062PheArg: 2.062 ± 1.553
3.351PheSer: 3.351 ± 1.003
4.897PheThr: 4.897 ± 2.776
1.546PheVal: 1.546 ± 0.661
0.773PheTrp: 0.773 ± 0.33
1.546PheTyr: 1.546 ± 0.661
0.0PheXaa: 0.0 ± 0.0
Gly
4.124GlyAla: 4.124 ± 1.762
0.773GlyCys: 0.773 ± 0.33
3.866GlyAsp: 3.866 ± 0.783
1.804GlyGlu: 1.804 ± 0.771
4.639GlyPhe: 4.639 ± 1.982
3.093GlyGly: 3.093 ± 1.321
3.866GlyHis: 3.866 ± 0.783
2.577GlyIle: 2.577 ± 1.101
6.443GlyLys: 6.443 ± 4.55
3.608GlyLeu: 3.608 ± 1.541
2.32GlyMet: 2.32 ± 0.201
2.577GlyAsn: 2.577 ± 1.333
3.608GlyPro: 3.608 ± 1.541
1.289GlyGln: 1.289 ± 0.551
3.608GlyArg: 3.608 ± 0.893
3.351GlySer: 3.351 ± 1.431
2.577GlyThr: 2.577 ± 3.767
2.32GlyVal: 2.32 ± 1.443
0.515GlyTrp: 0.515 ± 0.22
2.577GlyTyr: 2.577 ± 1.333
0.0GlyXaa: 0.0 ± 0.0
His
1.289HisAla: 1.289 ± 1.884
0.515HisCys: 0.515 ± 4.648
1.289HisAsp: 1.289 ± 0.551
2.32HisGlu: 2.32 ± 0.991
1.546HisPhe: 1.546 ± 0.661
1.031HisGly: 1.031 ± 1.994
1.289HisHis: 1.289 ± 1.884
1.546HisIle: 1.546 ± 1.774
1.289HisLys: 1.289 ± 0.551
2.835HisLeu: 2.835 ± 1.211
1.031HisMet: 1.031 ± 0.44
0.773HisAsn: 0.773 ± 0.33
1.031HisPro: 1.031 ± 0.44
0.515HisGln: 0.515 ± 0.22
1.546HisArg: 1.546 ± 0.661
4.124HisSer: 4.124 ± 1.762
2.062HisThr: 2.062 ± 0.881
2.835HisVal: 2.835 ± 1.223
0.773HisTrp: 0.773 ± 0.33
2.062HisTyr: 2.062 ± 0.881
0.0HisXaa: 0.0 ± 0.0
Ile
3.866IleAla: 3.866 ± 3.217
0.773IleCys: 0.773 ± 0.33
4.639IleAsp: 4.639 ± 0.452
2.577IleGlu: 2.577 ± 1.101
1.289IlePhe: 1.289 ± 1.884
2.32IleGly: 2.32 ± 0.991
1.031IleHis: 1.031 ± 0.44
1.546IleIle: 1.546 ± 1.774
3.608IleLys: 3.608 ± 1.541
4.124IleLeu: 4.124 ± 1.762
0.773IleMet: 0.773 ± 0.33
3.351IleAsn: 3.351 ± 1.431
3.351IlePro: 3.351 ± 1.431
2.062IleGln: 2.062 ± 0.881
3.866IleArg: 3.866 ± 0.783
3.351IleSer: 3.351 ± 1.003
4.639IleThr: 4.639 ± 1.982
3.351IleVal: 3.351 ± 1.431
1.804IleTrp: 1.804 ± 0.771
2.062IleTyr: 2.062 ± 0.881
0.0IleXaa: 0.0 ± 0.0
Lys
3.093LysAla: 3.093 ± 3.547
1.031LysCys: 1.031 ± 0.44
2.062LysAsp: 2.062 ± 0.881
3.351LysGlu: 3.351 ± 1.003
3.351LysPhe: 3.351 ± 1.003
3.866LysGly: 3.866 ± 1.652
1.804LysHis: 1.804 ± 0.771
3.093LysIle: 3.093 ± 1.113
2.835LysLys: 2.835 ± 1.223
4.124LysLeu: 4.124 ± 1.762
1.804LysMet: 1.804 ± 0.771
3.866LysAsn: 3.866 ± 1.652
3.093LysPro: 3.093 ± 1.321
2.062LysGln: 2.062 ± 0.881
4.897LysArg: 4.897 ± 2.776
5.928LysSer: 5.928 ± 4.77
2.577LysThr: 2.577 ± 1.101
2.577LysVal: 2.577 ± 1.101
0.0LysTrp: 0.0 ± 0.0
2.835LysTyr: 2.835 ± 1.211
0.0LysXaa: 0.0 ± 0.0
Leu
7.732LeuAla: 7.732 ± 3.303
0.773LeuCys: 0.773 ± 0.33
5.412LeuAsp: 5.412 ± 0.122
5.67LeuGlu: 5.67 ± 0.012
2.835LeuPhe: 2.835 ± 1.223
7.216LeuGly: 7.216 ± 1.786
2.32LeuHis: 2.32 ± 3.878
4.381LeuIle: 4.381 ± 1.872
5.412LeuLys: 5.412 ± 2.556
7.216LeuLeu: 7.216 ± 1.786
1.546LeuMet: 1.546 ± 0.661
2.32LeuAsn: 2.32 ± 0.991
3.093LeuPro: 3.093 ± 1.321
2.577LeuGln: 2.577 ± 1.333
3.866LeuArg: 3.866 ± 0.783
7.474LeuSer: 7.474 ± 1.675
3.093LeuThr: 3.093 ± 1.321
3.608LeuVal: 3.608 ± 3.327
3.351LeuTrp: 3.351 ± 1.431
3.866LeuTyr: 3.866 ± 0.783
0.0LeuXaa: 0.0 ± 0.0
Met
2.577MetAla: 2.577 ± 1.101
0.258MetCys: 0.258 ± 0.11
1.804MetAsp: 1.804 ± 1.664
1.804MetGlu: 1.804 ± 1.664
1.546MetPhe: 1.546 ± 0.661
1.289MetGly: 1.289 ± 0.551
0.773MetHis: 0.773 ± 0.33
1.289MetIle: 1.289 ± 0.551
1.031MetLys: 1.031 ± 0.44
1.804MetLeu: 1.804 ± 0.771
1.546MetMet: 1.546 ± 0.661
1.546MetAsn: 1.546 ± 0.661
2.062MetPro: 2.062 ± 0.881
1.031MetGln: 1.031 ± 0.44
2.32MetArg: 2.32 ± 0.991
1.546MetSer: 1.546 ± 0.661
1.804MetThr: 1.804 ± 0.771
1.289MetVal: 1.289 ± 1.884
1.289MetTrp: 1.289 ± 0.551
0.515MetTyr: 0.515 ± 0.22
0.0MetXaa: 0.0 ± 0.0
Asn
1.804AsnAla: 1.804 ± 1.664
0.773AsnCys: 0.773 ± 0.33
1.546AsnAsp: 1.546 ± 0.661
2.835AsnGlu: 2.835 ± 1.211
2.577AsnPhe: 2.577 ± 1.101
1.804AsnGly: 1.804 ± 1.664
0.773AsnHis: 0.773 ± 0.33
4.124AsnIle: 4.124 ± 1.762
3.093AsnLys: 3.093 ± 3.547
2.062AsnLeu: 2.062 ± 0.881
1.804AsnMet: 1.804 ± 0.771
2.32AsnAsn: 2.32 ± 0.991
2.835AsnPro: 2.835 ± 1.211
2.835AsnGln: 2.835 ± 1.211
2.32AsnArg: 2.32 ± 0.991
1.804AsnSer: 1.804 ± 0.771
2.32AsnThr: 2.32 ± 0.991
2.32AsnVal: 2.32 ± 0.991
0.258AsnTrp: 0.258 ± 0.11
1.289AsnTyr: 1.289 ± 0.551
0.0AsnXaa: 0.0 ± 0.0
Pro
4.124ProAla: 4.124 ± 0.673
0.258ProCys: 0.258 ± 0.11
3.866ProAsp: 3.866 ± 0.783
2.835ProGlu: 2.835 ± 1.211
1.804ProPhe: 1.804 ± 0.771
3.093ProGly: 3.093 ± 1.321
1.546ProHis: 1.546 ± 0.661
1.804ProIle: 1.804 ± 0.771
4.124ProLys: 4.124 ± 0.673
4.897ProLeu: 4.897 ± 2.092
1.031ProMet: 1.031 ± 1.994
1.804ProAsn: 1.804 ± 0.771
2.062ProPro: 2.062 ± 1.553
1.546ProGln: 1.546 ± 0.661
3.608ProArg: 3.608 ± 1.541
3.608ProSer: 3.608 ± 1.541
4.124ProThr: 4.124 ± 0.673
3.608ProVal: 3.608 ± 1.541
1.546ProTrp: 1.546 ± 0.661
3.093ProTyr: 3.093 ± 1.321
0.0ProXaa: 0.0 ± 0.0
Gln
2.32GlnAla: 2.32 ± 0.991
0.515GlnCys: 0.515 ± 0.22
1.289GlnAsp: 1.289 ± 0.551
0.773GlnGlu: 0.773 ± 0.33
1.289GlnPhe: 1.289 ± 0.551
2.32GlnGly: 2.32 ± 0.991
1.031GlnHis: 1.031 ± 0.44
0.773GlnIle: 0.773 ± 0.33
1.546GlnLys: 1.546 ± 0.661
3.351GlnLeu: 3.351 ± 5.871
2.32GlnMet: 2.32 ± 0.991
1.289GlnAsn: 1.289 ± 0.551
1.546GlnPro: 1.546 ± 0.661
1.289GlnGln: 1.289 ± 0.551
2.062GlnArg: 2.062 ± 0.881
2.062GlnSer: 2.062 ± 0.881
2.577GlnThr: 2.577 ± 1.101
2.577GlnVal: 2.577 ± 1.101
0.773GlnTrp: 0.773 ± 0.33
0.773GlnTyr: 0.773 ± 0.33
0.0GlnXaa: 0.0 ± 0.0
Arg
3.608ArgAla: 3.608 ± 1.541
0.258ArgCys: 0.258 ± 0.11
2.062ArgAsp: 2.062 ± 0.881
3.351ArgGlu: 3.351 ± 1.003
2.835ArgPhe: 2.835 ± 1.211
2.32ArgGly: 2.32 ± 1.443
3.093ArgHis: 3.093 ± 3.547
3.351ArgIle: 3.351 ± 1.003
3.608ArgLys: 3.608 ± 1.541
6.443ArgLeu: 6.443 ± 0.318
1.804ArgMet: 1.804 ± 0.771
3.093ArgAsn: 3.093 ± 1.113
5.155ArgPro: 5.155 ± 2.202
1.546ArgGln: 1.546 ± 1.774
6.959ArgArg: 6.959 ± 1.896
3.866ArgSer: 3.866 ± 3.217
4.124ArgThr: 4.124 ± 1.762
4.639ArgVal: 4.639 ± 1.982
0.258ArgTrp: 0.258 ± 0.11
2.32ArgTyr: 2.32 ± 1.443
0.0ArgXaa: 0.0 ± 0.0
Ser
5.155SerAla: 5.155 ± 2.202
1.031SerCys: 1.031 ± 0.44
2.835SerAsp: 2.835 ± 1.211
4.897SerGlu: 4.897 ± 5.211
3.608SerPhe: 3.608 ± 1.541
4.381SerGly: 4.381 ± 0.562
0.773SerHis: 0.773 ± 0.33
3.866SerIle: 3.866 ± 1.652
3.351SerLys: 3.351 ± 1.431
6.443SerLeu: 6.443 ± 2.116
1.289SerMet: 1.289 ± 1.884
2.062SerAsn: 2.062 ± 0.881
3.608SerPro: 3.608 ± 1.541
1.546SerGln: 1.546 ± 0.661
3.093SerArg: 3.093 ± 1.113
4.639SerSer: 4.639 ± 1.982
4.381SerThr: 4.381 ± 0.562
4.639SerVal: 4.639 ± 1.982
2.062SerTrp: 2.062 ± 0.881
2.32SerTyr: 2.32 ± 1.443
0.0SerXaa: 0.0 ± 0.0
Thr
4.381ThrAla: 4.381 ± 1.872
0.515ThrCys: 0.515 ± 0.22
2.32ThrAsp: 2.32 ± 0.991
4.124ThrGlu: 4.124 ± 3.107
3.608ThrPhe: 3.608 ± 5.761
3.351ThrGly: 3.351 ± 1.003
2.32ThrHis: 2.32 ± 0.991
3.866ThrIle: 3.866 ± 0.783
2.32ThrLys: 2.32 ± 0.991
4.897ThrLeu: 4.897 ± 0.342
2.062ThrMet: 2.062 ± 0.881
2.835ThrAsn: 2.835 ± 1.211
4.124ThrPro: 4.124 ± 0.673
1.804ThrGln: 1.804 ± 1.664
4.897ThrArg: 4.897 ± 2.092
3.351ThrSer: 3.351 ± 1.003
2.32ThrThr: 2.32 ± 1.443
2.062ThrVal: 2.062 ± 0.881
0.258ThrTrp: 0.258 ± 0.11
2.577ThrTyr: 2.577 ± 1.101
0.0ThrXaa: 0.0 ± 0.0
Val
5.67ValAla: 5.67 ± 2.446
0.773ValCys: 0.773 ± 0.33
3.093ValAsp: 3.093 ± 1.321
3.608ValGlu: 3.608 ± 1.541
2.835ValPhe: 2.835 ± 1.223
2.835ValGly: 2.835 ± 1.211
2.062ValHis: 2.062 ± 0.881
2.577ValIle: 2.577 ± 1.101
1.804ValLys: 1.804 ± 0.771
7.474ValLeu: 7.474 ± 3.193
2.062ValMet: 2.062 ± 0.881
1.546ValAsn: 1.546 ± 4.208
4.381ValPro: 4.381 ± 0.562
1.804ValGln: 1.804 ± 0.771
3.093ValArg: 3.093 ± 1.113
5.155ValSer: 5.155 ± 2.202
2.062ValThr: 2.062 ± 1.553
6.186ValVal: 6.186 ± 0.208
0.773ValTrp: 0.773 ± 2.104
1.031ValTyr: 1.031 ± 0.44
0.0ValXaa: 0.0 ± 0.0
Trp
1.031TrpAla: 1.031 ± 0.44
0.258TrpCys: 0.258 ± 0.11
1.289TrpAsp: 1.289 ± 1.884
0.773TrpGlu: 0.773 ± 0.33
1.031TrpPhe: 1.031 ± 0.44
1.289TrpGly: 1.289 ± 0.551
0.258TrpHis: 0.258 ± 0.11
1.289TrpIle: 1.289 ± 0.551
1.031TrpLys: 1.031 ± 0.44
2.32TrpLeu: 2.32 ± 1.443
0.773TrpMet: 0.773 ± 0.33
1.031TrpAsn: 1.031 ± 0.44
0.258TrpPro: 0.258 ± 0.11
0.258TrpGln: 0.258 ± 0.11
1.546TrpArg: 1.546 ± 1.774
1.804TrpSer: 1.804 ± 0.771
1.031TrpThr: 1.031 ± 1.994
2.062TrpVal: 2.062 ± 0.881
0.258TrpTrp: 0.258 ± 0.11
1.031TrpTyr: 1.031 ± 0.44
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.124TyrAla: 4.124 ± 1.762
0.258TyrCys: 0.258 ± 0.11
2.32TyrAsp: 2.32 ± 3.878
2.062TyrGlu: 2.062 ± 0.881
1.031TyrPhe: 1.031 ± 0.44
2.835TyrGly: 2.835 ± 1.211
2.32TyrHis: 2.32 ± 1.443
1.546TyrIle: 1.546 ± 0.661
2.577TyrLys: 2.577 ± 1.101
3.608TyrLeu: 3.608 ± 3.327
1.546TyrMet: 1.546 ± 0.619
1.804TyrAsn: 1.804 ± 0.771
0.773TyrPro: 0.773 ± 0.33
1.031TyrGln: 1.031 ± 0.44
2.062TyrArg: 2.062 ± 0.881
2.835TyrSer: 2.835 ± 1.211
1.289TyrThr: 1.289 ± 0.551
2.577TyrVal: 2.577 ± 1.333
0.258TyrTrp: 0.258 ± 0.11
0.515TyrTyr: 0.515 ± 0.22
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3881 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski