Amino acid dipepetide frequency for Cattle blood-associated gemycircularvirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.311AlaAla: 1.311 ± 0.794
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
5.242AlaGlu: 5.242 ± 1.348
3.932AlaPhe: 3.932 ± 1.273
2.621AlaGly: 2.621 ± 1.587
1.311AlaHis: 1.311 ± 0.794
0.0AlaIle: 0.0 ± 0.0
1.311AlaLys: 1.311 ± 0.794
2.621AlaLeu: 2.621 ± 0.239
1.311AlaMet: 1.311 ± 0.624
3.932AlaAsn: 3.932 ± 0.554
1.311AlaPro: 1.311 ± 0.794
3.932AlaGln: 3.932 ± 1.273
5.242AlaArg: 5.242 ± 4.132
3.932AlaSer: 3.932 ± 2.381
2.621AlaThr: 2.621 ± 1.587
3.932AlaVal: 3.932 ± 0.554
1.311AlaTrp: 1.311 ± 0.794
2.621AlaTyr: 2.621 ± 0.239
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.311CysCys: 1.311 ± 0.794
1.311CysAsp: 1.311 ± 1.033
1.311CysGlu: 1.311 ± 1.033
2.621CysPhe: 2.621 ± 0.239
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.311CysIle: 1.311 ± 0.794
2.621CysLys: 2.621 ± 0.239
0.0CysLeu: 0.0 ± 0.0
1.311CysMet: 1.311 ± 0.794
3.932CysAsn: 3.932 ± 1.273
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.311CysSer: 1.311 ± 0.794
2.621CysThr: 2.621 ± 0.239
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.311CysTyr: 1.311 ± 0.794
0.0CysXaa: 0.0 ± 0.0
Asp
2.621AspAla: 2.621 ± 0.239
2.621AspCys: 2.621 ± 2.066
1.311AspAsp: 1.311 ± 1.033
2.621AspGlu: 2.621 ± 0.239
0.0AspPhe: 0.0 ± 0.0
1.311AspGly: 1.311 ± 1.033
0.0AspHis: 0.0 ± 0.0
5.242AspIle: 5.242 ± 0.479
3.932AspLys: 3.932 ± 3.099
3.932AspLeu: 3.932 ± 0.554
1.311AspMet: 1.311 ± 1.033
3.932AspAsn: 3.932 ± 0.554
1.311AspPro: 1.311 ± 1.033
1.311AspGln: 1.311 ± 0.794
1.311AspArg: 1.311 ± 1.033
0.0AspSer: 0.0 ± 0.0
6.553AspThr: 6.553 ± 0.315
1.311AspVal: 1.311 ± 0.794
2.621AspTrp: 2.621 ± 2.066
3.932AspTyr: 3.932 ± 0.554
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
1.311GluCys: 1.311 ± 0.794
3.932GluAsp: 3.932 ± 3.099
3.932GluGlu: 3.932 ± 3.099
2.621GluPhe: 2.621 ± 2.066
1.311GluGly: 1.311 ± 0.794
0.0GluHis: 0.0 ± 0.0
5.242GluIle: 5.242 ± 1.348
9.174GluLys: 9.174 ± 1.751
1.311GluLeu: 1.311 ± 1.033
0.0GluMet: 0.0 ± 0.0
3.932GluAsn: 3.932 ± 3.099
2.621GluPro: 2.621 ± 2.066
2.621GluGln: 2.621 ± 1.587
1.311GluArg: 1.311 ± 1.033
1.311GluSer: 1.311 ± 1.033
2.621GluThr: 2.621 ± 0.239
2.621GluVal: 2.621 ± 0.239
1.311GluTrp: 1.311 ± 1.033
2.621GluTyr: 2.621 ± 2.066
0.0GluXaa: 0.0 ± 0.0
Phe
1.311PheAla: 1.311 ± 0.794
2.621PheCys: 2.621 ± 0.239
5.242PheAsp: 5.242 ± 4.132
7.864PheGlu: 7.864 ± 0.718
2.621PhePhe: 2.621 ± 2.066
2.621PheGly: 2.621 ± 0.239
1.311PheHis: 1.311 ± 1.033
2.621PheIle: 2.621 ± 1.587
1.311PheLys: 1.311 ± 0.794
2.621PheLeu: 2.621 ± 0.239
1.311PheMet: 1.311 ± 0.794
10.485PheAsn: 10.485 ± 2.784
1.311PhePro: 1.311 ± 0.794
1.311PheGln: 1.311 ± 1.033
1.311PheArg: 1.311 ± 1.033
1.311PheSer: 1.311 ± 0.794
3.932PheThr: 3.932 ± 1.273
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.621GlyAla: 2.621 ± 0.239
0.0GlyCys: 0.0 ± 0.0
1.311GlyAsp: 1.311 ± 0.794
1.311GlyGlu: 1.311 ± 1.033
2.621GlyPhe: 2.621 ± 1.587
2.621GlyGly: 2.621 ± 1.587
1.311GlyHis: 1.311 ± 1.033
3.932GlyIle: 3.932 ± 0.554
7.864GlyLys: 7.864 ± 0.718
5.242GlyLeu: 5.242 ± 2.306
1.311GlyMet: 1.311 ± 0.794
1.311GlyAsn: 1.311 ± 0.794
3.932GlyPro: 3.932 ± 0.554
1.311GlyGln: 1.311 ± 0.794
2.621GlyArg: 2.621 ± 0.239
3.932GlySer: 3.932 ± 2.381
3.932GlyThr: 3.932 ± 0.554
2.621GlyVal: 2.621 ± 1.587
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.311HisAsp: 1.311 ± 0.794
1.311HisGlu: 1.311 ± 1.033
1.311HisPhe: 1.311 ± 1.033
0.0HisGly: 0.0 ± 0.0
2.621HisHis: 2.621 ± 1.587
1.311HisIle: 1.311 ± 1.033
1.311HisLys: 1.311 ± 0.794
1.311HisLeu: 1.311 ± 0.794
1.311HisMet: 1.311 ± 1.033
0.0HisAsn: 0.0 ± 0.0
2.621HisPro: 2.621 ± 2.066
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.311HisThr: 1.311 ± 0.794
3.932HisVal: 3.932 ± 0.554
0.0HisTrp: 0.0 ± 0.0
1.311HisTyr: 1.311 ± 1.033
0.0HisXaa: 0.0 ± 0.0
Ile
3.932IleAla: 3.932 ± 0.554
0.0IleCys: 0.0 ± 0.0
1.311IleAsp: 1.311 ± 1.033
1.311IleGlu: 1.311 ± 1.033
2.621IlePhe: 2.621 ± 0.239
5.242IleGly: 5.242 ± 0.479
0.0IleHis: 0.0 ± 0.0
2.621IleIle: 2.621 ± 0.239
3.932IleLys: 3.932 ± 0.554
3.932IleLeu: 3.932 ± 0.554
2.621IleMet: 2.621 ± 0.239
1.311IleAsn: 1.311 ± 0.794
2.621IlePro: 2.621 ± 2.066
2.621IleGln: 2.621 ± 0.239
5.242IleArg: 5.242 ± 0.479
6.553IleSer: 6.553 ± 2.142
5.242IleThr: 5.242 ± 3.175
2.621IleVal: 2.621 ± 1.587
2.621IleTrp: 2.621 ± 0.239
6.553IleTyr: 6.553 ± 0.315
0.0IleXaa: 0.0 ± 0.0
Lys
2.621LysAla: 2.621 ± 0.239
3.932LysCys: 3.932 ± 0.554
3.932LysAsp: 3.932 ± 0.554
5.242LysGlu: 5.242 ± 4.132
3.932LysPhe: 3.932 ± 2.381
2.621LysGly: 2.621 ± 0.239
3.932LysHis: 3.932 ± 0.554
7.864LysIle: 7.864 ± 2.935
3.932LysLys: 3.932 ± 2.381
5.242LysLeu: 5.242 ± 2.306
1.311LysMet: 1.311 ± 0.794
3.932LysAsn: 3.932 ± 1.273
2.621LysPro: 2.621 ± 0.239
1.311LysGln: 1.311 ± 1.033
5.242LysArg: 5.242 ± 1.348
1.311LysSer: 1.311 ± 1.033
2.621LysThr: 2.621 ± 0.239
3.932LysVal: 3.932 ± 0.554
2.621LysTrp: 2.621 ± 0.239
7.864LysTyr: 7.864 ± 2.545
0.0LysXaa: 0.0 ± 0.0
Leu
3.932LeuAla: 3.932 ± 1.273
0.0LeuCys: 0.0 ± 0.0
5.242LeuAsp: 5.242 ± 2.306
1.311LeuGlu: 1.311 ± 1.033
5.242LeuPhe: 5.242 ± 0.479
2.621LeuGly: 2.621 ± 0.239
0.0LeuHis: 0.0 ± 0.0
2.621LeuIle: 2.621 ± 2.066
1.311LeuLys: 1.311 ± 0.794
1.311LeuLeu: 1.311 ± 1.033
0.0LeuMet: 0.0 ± 0.0
2.621LeuAsn: 2.621 ± 2.066
3.932LeuPro: 3.932 ± 2.381
0.0LeuGln: 0.0 ± 0.0
10.485LeuArg: 10.485 ± 2.784
1.311LeuSer: 1.311 ± 0.794
7.864LeuThr: 7.864 ± 1.109
6.553LeuVal: 6.553 ± 3.968
2.621LeuTrp: 2.621 ± 0.239
5.242LeuTyr: 5.242 ± 2.306
0.0LeuXaa: 0.0 ± 0.0
Met
2.621MetAla: 2.621 ± 0.239
0.0MetCys: 0.0 ± 0.0
1.311MetAsp: 1.311 ± 1.033
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
6.553MetIle: 6.553 ± 0.315
1.311MetLys: 1.311 ± 0.794
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.311MetPro: 1.311 ± 0.794
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.311MetSer: 1.311 ± 1.033
1.311MetThr: 1.311 ± 0.794
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.311MetTyr: 1.311 ± 1.033
0.0MetXaa: 0.0 ± 0.0
Asn
1.311AsnAla: 1.311 ± 0.794
2.621AsnCys: 2.621 ± 0.239
1.311AsnAsp: 1.311 ± 1.033
2.621AsnGlu: 2.621 ± 0.239
3.932AsnPhe: 3.932 ± 1.273
1.311AsnGly: 1.311 ± 1.033
1.311AsnHis: 1.311 ± 1.033
0.0AsnIle: 0.0 ± 0.0
3.932AsnLys: 3.932 ± 1.273
10.485AsnLeu: 10.485 ± 2.696
2.621AsnMet: 2.621 ± 0.239
7.864AsnAsn: 7.864 ± 1.109
5.242AsnPro: 5.242 ± 3.175
1.311AsnGln: 1.311 ± 0.794
6.553AsnArg: 6.553 ± 3.968
3.932AsnSer: 3.932 ± 1.273
1.311AsnThr: 1.311 ± 0.794
6.553AsnVal: 6.553 ± 1.512
1.311AsnTrp: 1.311 ± 1.033
3.932AsnTyr: 3.932 ± 0.554
0.0AsnXaa: 0.0 ± 0.0
Pro
6.553ProAla: 6.553 ± 3.968
0.0ProCys: 0.0 ± 0.0
2.621ProAsp: 2.621 ± 0.239
2.621ProGlu: 2.621 ± 1.587
2.621ProPhe: 2.621 ± 0.239
2.621ProGly: 2.621 ± 1.587
1.311ProHis: 1.311 ± 1.033
2.621ProIle: 2.621 ± 0.239
2.621ProLys: 2.621 ± 0.239
3.932ProLeu: 3.932 ± 1.273
0.0ProMet: 0.0 ± 0.0
2.621ProAsn: 2.621 ± 1.587
1.311ProPro: 1.311 ± 0.794
2.621ProGln: 2.621 ± 2.066
1.311ProArg: 1.311 ± 0.794
5.242ProSer: 5.242 ± 4.132
5.242ProThr: 5.242 ± 3.175
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
2.621ProTyr: 2.621 ± 2.066
0.0ProXaa: 0.0 ± 0.0
Gln
3.932GlnAla: 3.932 ± 1.273
0.0GlnCys: 0.0 ± 0.0
1.311GlnAsp: 1.311 ± 0.794
0.0GlnGlu: 0.0 ± 0.0
3.932GlnPhe: 3.932 ± 1.273
2.621GlnGly: 2.621 ± 1.587
0.0GlnHis: 0.0 ± 0.0
2.621GlnIle: 2.621 ± 0.239
5.242GlnLys: 5.242 ± 0.479
3.932GlnLeu: 3.932 ± 1.273
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.311GlnPro: 1.311 ± 0.794
1.311GlnGln: 1.311 ± 0.794
1.311GlnArg: 1.311 ± 0.794
2.621GlnSer: 2.621 ± 1.587
1.311GlnThr: 1.311 ± 0.794
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.932ArgAla: 3.932 ± 0.554
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
1.311ArgGlu: 1.311 ± 1.033
2.621ArgPhe: 2.621 ± 0.239
2.621ArgGly: 2.621 ± 2.066
1.311ArgHis: 1.311 ± 1.033
5.242ArgIle: 5.242 ± 1.348
7.864ArgLys: 7.864 ± 1.109
5.242ArgLeu: 5.242 ± 1.348
0.0ArgMet: 0.0 ± 0.0
3.932ArgAsn: 3.932 ± 0.554
5.242ArgPro: 5.242 ± 0.479
5.242ArgGln: 5.242 ± 1.348
6.553ArgArg: 6.553 ± 3.968
6.553ArgSer: 6.553 ± 0.315
3.932ArgThr: 3.932 ± 0.554
2.621ArgVal: 2.621 ± 2.066
0.0ArgTrp: 0.0 ± 0.0
5.242ArgTyr: 5.242 ± 0.479
0.0ArgXaa: 0.0 ± 0.0
Ser
5.242SerAla: 5.242 ± 1.348
1.311SerCys: 1.311 ± 0.794
0.0SerAsp: 0.0 ± 0.0
0.0SerGlu: 0.0 ± 0.0
1.311SerPhe: 1.311 ± 0.794
0.0SerGly: 0.0 ± 0.0
1.311SerHis: 1.311 ± 0.794
1.311SerIle: 1.311 ± 1.033
3.932SerLys: 3.932 ± 0.554
2.621SerLeu: 2.621 ± 0.239
0.0SerMet: 0.0 ± 0.0
5.242SerAsn: 5.242 ± 1.348
0.0SerPro: 0.0 ± 0.0
3.932SerGln: 3.932 ± 0.554
7.864SerArg: 7.864 ± 2.935
6.553SerSer: 6.553 ± 2.142
7.864SerThr: 7.864 ± 0.718
6.553SerVal: 6.553 ± 0.315
3.932SerTrp: 3.932 ± 1.273
1.311SerTyr: 1.311 ± 1.033
0.0SerXaa: 0.0 ± 0.0
Thr
1.311ThrAla: 1.311 ± 0.794
2.621ThrCys: 2.621 ± 0.239
7.864ThrAsp: 7.864 ± 2.935
3.932ThrGlu: 3.932 ± 3.099
1.311ThrPhe: 1.311 ± 0.794
5.242ThrGly: 5.242 ± 2.306
1.311ThrHis: 1.311 ± 0.794
1.311ThrIle: 1.311 ± 0.794
3.932ThrLys: 3.932 ± 3.099
3.932ThrLeu: 3.932 ± 0.554
0.0ThrMet: 0.0 ± 0.0
5.242ThrAsn: 5.242 ± 3.175
5.242ThrPro: 5.242 ± 3.175
2.621ThrGln: 2.621 ± 1.587
5.242ThrArg: 5.242 ± 1.348
5.242ThrSer: 5.242 ± 3.175
7.864ThrThr: 7.864 ± 4.762
6.553ThrVal: 6.553 ± 0.315
1.311ThrTrp: 1.311 ± 0.794
2.621ThrTyr: 2.621 ± 0.239
0.0ThrXaa: 0.0 ± 0.0
Val
2.621ValAla: 2.621 ± 1.587
1.311ValCys: 1.311 ± 0.794
2.621ValAsp: 2.621 ± 0.239
3.932ValGlu: 3.932 ± 1.273
1.311ValPhe: 1.311 ± 1.033
7.864ValGly: 7.864 ± 4.762
1.311ValHis: 1.311 ± 0.794
1.311ValIle: 1.311 ± 0.794
6.553ValLys: 6.553 ± 2.142
0.0ValLeu: 0.0 ± 0.0
1.311ValMet: 1.311 ± 1.033
3.932ValAsn: 3.932 ± 0.554
1.311ValPro: 1.311 ± 1.033
0.0ValGln: 0.0 ± 0.0
6.553ValArg: 6.553 ± 0.315
2.621ValSer: 2.621 ± 1.587
2.621ValThr: 2.621 ± 2.066
3.932ValVal: 3.932 ± 2.381
0.0ValTrp: 0.0 ± 0.0
7.864ValTyr: 7.864 ± 1.109
0.0ValXaa: 0.0 ± 0.0
Trp
1.311TrpAla: 1.311 ± 1.033
0.0TrpCys: 0.0 ± 0.0
1.311TrpAsp: 1.311 ± 1.033
1.311TrpGlu: 1.311 ± 1.033
0.0TrpPhe: 0.0 ± 0.0
2.621TrpGly: 2.621 ± 0.239
1.311TrpHis: 1.311 ± 1.033
1.311TrpIle: 1.311 ± 1.033
2.621TrpLys: 2.621 ± 0.239
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.311TrpAsn: 1.311 ± 0.794
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
2.621TrpThr: 2.621 ± 1.587
2.621TrpVal: 2.621 ± 0.239
0.0TrpTrp: 0.0 ± 0.0
2.621TrpTyr: 2.621 ± 0.239
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.311TyrAla: 1.311 ± 1.033
1.311TyrCys: 1.311 ± 1.033
3.932TyrAsp: 3.932 ± 0.554
2.621TyrGlu: 2.621 ± 0.239
6.553TyrPhe: 6.553 ± 3.339
3.932TyrGly: 3.932 ± 2.381
1.311TyrHis: 1.311 ± 1.033
7.864TyrIle: 7.864 ± 0.718
1.311TyrLys: 1.311 ± 1.033
6.553TyrLeu: 6.553 ± 3.339
0.0TyrMet: 0.0 ± 0.706
3.932TyrAsn: 3.932 ± 2.381
5.242TyrPro: 5.242 ± 2.306
0.0TyrGln: 0.0 ± 0.0
1.311TyrArg: 1.311 ± 1.033
5.242TyrSer: 5.242 ± 2.306
1.311TyrThr: 1.311 ± 0.794
2.621TyrVal: 2.621 ± 1.587
1.311TyrTrp: 1.311 ± 0.794
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (764 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski